EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
ACC	chr22	40021789	Missense_Mutation	novel	A427T	0.23
BLCA	chr22	40019269	Silent	rs141929176	D197D	0.16
BLCA	chr22	40019257	Silent	NA	Y193Y	0.23
BLCA	chr22	40021820	Missense_Mutation	rs775584186	R437H	0.36
BLCA	chr22	40019991	Silent	NA	V254V	0.66
BLCA	chr22	40019310	Missense_Mutation	novel	L211P	0.24
BLCA	chr22	40021883	Missense_Mutation	NA	S458N	0.16
BRCA	chr22	40021315	Missense_Mutation	novel	D269Y	0.14
BRCA	chr22	40029534	Missense_Mutation	NA	S491Y	0.39
BRCA	chr22	40021457	Missense_Mutation	NA	S316F	0.41
BRCA	chr22	40044952	3'Flank	novel		0.4
BRCA	chr22	40019270	Missense_Mutation	NA	E198K	0.38
CESC	chr22	40019269	Silent	rs141929176	D197D	0.49
CESC	chr22	40019175	Missense_Mutation	rs762810344	A166D	0.35
CESC	chr22	40021813	Missense_Mutation	rs567145342	A435T	0.33
CESC	chr22	40019269	Silent	rs141929176	D197D	0.28
CESC	chr22	39995465	Silent	novel	P141P	0.24
CESC	chr22	40044913	3'Flank	novel		0.33
CESC	chr22	40019270	Nonsense_Mutation	novel	E198*	0.37
COAD	chr22	40021490	Missense_Mutation	novel	Y327F	0.21
COAD	chr22	40021639	Missense_Mutation	novel	D377Y	0.18
COAD	chr22	40021667	Missense_Mutation	novel	P386H	0.15
COAD	chr22	40021595	Missense_Mutation	novel	A362V	0.35
COAD	chr22	40021337	Missense_Mutation	novel	L276R	0.1
ESCA	chr22	40021665	Frame_Shift_Ins	novel	*V388Rfs79**	0.3
ESCA	chr22	40021721	Frame_Shift_Ins	novel	*H406Afs8**	0.38
ESCA	chr22	39995297	Silent	novel	G85G	0.5
GBM	chr22	40021575	Silent	rs573958791	P355P	0.28
GBM	chr22	40019205	Frame_Shift_Del	novel	*D176Vfs26**	0.07
GBM	chr22	40021566	Silent	rs763939183	G352G	0.5
HNSC	chr22	40021465	Frame_Shift_Del	novel	*R320Gfs33**	0.24
HNSC	chr22	40021671	Silent	rs776961253	P387P	0.24
KIRC	chr22	40021852	Frame_Shift_Del	novel	*K448Rfs23**	0.19
LGG	chr22	40021582	Nonsense_Mutation	novel	Q358*	0.22
LUAD	chr22	40021375	Missense_Mutation	rs761040921	R289W	0.07
LUAD	chr22	40021506	Silent	novel	G332G	0.26
LUAD	chr22	40021507	Missense_Mutation	novel	C333S	0.25
LUAD	chr22	40029579	3'UTR	novel		0.5
LUAD	chr22	40021315	Missense_Mutation	novel	D269Y	0.92
LUAD	chr22	40019198	Missense_Mutation	novel	D174N	0.19
LUAD	chr22	40021815	Frame_Shift_Ins	novel	*R436Efs31**	0.2
LUAD	chr22	40019321	Missense_Mutation	novel	D215Y	0.86
LUAD	chr22	40021812	Silent	NA	P434P	0.38
LUAD	chr22	40019239	Missense_Mutation	novel	K187N	0.09
LUAD	chr22	40019914	Missense_Mutation	novel	V229F	0.29
LUSC	chr22	40029648	3'UTR	novel		1
LUSC	chr22	40021923	Frame_Shift_Del	novel	*K473Rfs26**	0.14
LUSC	chr22	40019195	Missense_Mutation	novel	T173A	0.19
LUSC	chr22	40019243	Silent	NA	R189R	0.36
LUSC	chr22	40021593	Silent	NA	G361G	0.42
LUSC	chr22	40021707	Missense_Mutation	NA	K399N	0.43
PRAD	chr22	40021436	Missense_Mutation	novel	R309M	0.06
PRAD	chr22	40021334	Missense_Mutation	novel	L275P	0.08
SARC	chr22	39995369	Silent	novel	P109P	0.4
SARC	chr22	40021547	Missense_Mutation	rs201378321	R346Q	0.33
SARC	chr22	40021722	Silent	novel	V404V	0.25
SARC	chr22	40021800	Silent	novel	G430G	0.51
SKCM	chr22	40021839	Silent	NA	F443F	0.39
SKCM	chr22	40019244	Missense_Mutation	rs373369149	R189Q	0.27
SKCM	chr22	40019931	Silent	rs142043340	P234P	0.45
SKCM	chr22	40021680	Silent	novel	P390P	0.98
SKCM	chr22	40021684	Missense_Mutation	NA	P392S	0.21
SKCM	chr22	40019999	Missense_Mutation	NA	G257E	0.27
SKCM	chr22	40019290	Missense_Mutation	NA	F204L	0.64
SKCM	chr22	40021369	Missense_Mutation	NA	E287K	0.92
SKCM	chr22	40021612	Missense_Mutation	rs746620839	A368T	0.9
SKCM	chr22	40021394	Missense_Mutation	novel	S295F	0.28
SKCM	chr22	40021502	Missense_Mutation	NA	S331L	0.42
SKCM	chr22	40021809	Silent	novel	A433A	0.37
SKCM	chr22	40021530	Missense_Mutation	NA	M340I	0.31
SKCM	chr22	40019277	Missense_Mutation	novel	G200E	0.36
SKCM	chr22	40021502	Missense_Mutation	NA	S331L	0.06
SKCM	chr22	40021685	Missense_Mutation	novel	P392R	0.24
SKCM	chr22	40021686	Silent	novel	P392P	0.24
SKCM	chr22	40021330	Silent	NA	L274L	0.36
SKCM	chr22	40021324	Missense_Mutation	NA	L272F	0.35
SKCM	chr22	40021707	Silent	rs780982282	K399K	0.23
SKCM	chr22	40021755	Silent	NA	S415S	0.35
SKCM	chr22	40019267	Missense_Mutation	NA	D197N	0.2
SKCM	chr22	40019899	Missense_Mutation	rs141068393	R224C	0.14
SKCM	chr22	40019266	Silent	novel	L196L	0.3
SKCM	chr22	40021783	Missense_Mutation	NA	G425R	0.21
SKCM	chr22	40029515	Splice_Site	NA	X485_splice	0.23
SKCM	chr22	40021432	Missense_Mutation	novel	G308S	0.31
SKCM	chr22	40021433	Missense_Mutation	novel	G308D	0.31
SKCM	chr22	40021800	Silent	novel	G430G	0.45
SKCM	chr22	40029561	Missense_Mutation	novel	S500F	0.75
STAD	chr22	40021546	Missense_Mutation	rs145428025	R346W	0.15
STAD	chr22	40021541	Missense_Mutation	NA	A344V	0.3
STAD	chr22	40021665	Frame_Shift_Ins	novel	*V388Rfs79**	0.16
STAD	chr22	40021796	Frame_Shift_Del	NA	*E431Rfs40**	0.26
STAD	chr22	40021813	Missense_Mutation	rs567145342	A435T	0.31
STAD	chr22	40021879	Missense_Mutation	rs778728277	A457T	0.22
STAD	chr22	40021468	Nonsense_Mutation	novel	R320*	0.36
STAD	chr22	40021650	Silent	rs551543842	T380T	0.21
STAD	chr22	40019240	Missense_Mutation	rs754481227	R188C	0.25
STAD	chr22	40021950	Silent	NA	S480S	0.18
STAD	chr22	40021796	Frame_Shift_Del	NA	*E431Rfs40**	0.35
STAD	chr22	40021835	Missense_Mutation	NA	L442H	0.24
STAD	chr22	40021463	Missense_Mutation	novel	V318A	0.06
STAD	chr22	40019893	Missense_Mutation	rs531840891	R222C	0.16
THCA	chr22	40021405	Missense_Mutation	NA	D299N	0.09
THYM	chr22	40029796	3'UTR	novel		0.15
UCEC	chr22	40021594	Missense_Mutation	rs758495757	A362T	0.51
UCEC	chr22	40029753	3'UTR	novel		0.32
UCEC	chr22	40021772	Missense_Mutation	rs141861984	R421Q	0.27
UCEC	chr22	40019175	Missense_Mutation	novel	A166V	0.32
UCEC	chr22	40021388	Missense_Mutation	NA	A293V	0.24
UCEC	chr22	40021922	Missense_Mutation	rs781508185	T471M	0.43
UCEC	chr22	40019328	Missense_Mutation	NA	R217Q	0.4
UCEC	chr22	40021772	Missense_Mutation	rs141861984	R421Q	0.29
UCEC	chr22	40029894	3'UTR	novel		0.39
UCEC	chr22	40029793	3'UTR	novel		0.36
UCEC	chr22	40029857	3'UTR	novel		0.42
UCEC	chr22	40019917	Missense_Mutation	rs758127931	G230S	0.26
UCEC	chr22	40021368	Silent	rs115837035	T286T	0.41
UCEC	chr22	40019900	Missense_Mutation	rs536050162	R224H	0.31
UCEC	chr22	40021468	Nonsense_Mutation	novel	R320*	0.69
UCEC	chr22	40021339	Missense_Mutation	novel	T277A	0.29
UCEC	chr22	40021593	Silent	NA	G361G	0.09
UCEC	chr22	40029797	3'UTR	rs529508588		0.47
UCEC	chr22	40044942	3'Flank	novel		0.56
UCEC	chr22	39995435	Silent	novel	G131G	0.27
UCEC	chr22	40019209	Silent	novel	I177I	0.23
UCEC	chr22	40021333	Missense_Mutation	novel	L275F	0.31

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
PCPG	DEL	0.3333	0.044123
THCA	DEL	0.1563	0.046486
THYM	DEL	0.0732	0.063154

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0054	Kaplan-Meier Survival Analysis
SKCM	0.012	Kaplan-Meier Survival Analysis
KIRP	0.001	Kaplan-Meier Survival Analysis
COAD	0.04	Kaplan-Meier Survival Analysis
PAAD	0.0013	Kaplan-Meier Survival Analysis
BLCA	0.049	Kaplan-Meier Survival Analysis
READ	0.003	Kaplan-Meier Survival Analysis
LAML	0.00043	Kaplan-Meier Survival Analysis
KICH	0.049	Kaplan-Meier Survival Analysis
GBM	0.00037	Kaplan-Meier Survival Analysis
LUAD	0.011	Kaplan-Meier Survival Analysis
UVM	0.04	Kaplan-Meier Survival Analysis

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Description

Ensembl ID: ENSG00000133477 (Gene tree)
Gene ID: 113828
Gene Symbol: FAM83F
Alias: -
Full Name: family with sequence similarity 83 member F
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 48,581 bases
Position: chr22:39,994,949-40,043,529
Accession: 25148
RBP type: canonical RBP
Summary: FAM83F (Family With Sequence Similarity 83 Member F) is a Protein Coding gene. An important paralog of this gene is FAM83G.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000330432	FAM83	PF07894.12	3.7e-108	1	1
ENSP00000476600	FAM83	PF07894.12	1.2e-54	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000473717	FAM83F-202	1917	-	ENSP00000476600	332 (aa)	-	Q8NEG4
ENST00000488874	FAM83F-203	561	-	-	- (aa)	-	-
ENST00000333407	FAM83F-201	15561	-	ENSP00000330432	500 (aa)	-	Q8NEG4

Gene Model

Click here to download ENSG00000133477's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000133477	Prostatic Neoplasms	4E-7	23065704
ENSG00000133477	Prostatic Neoplasms	4E-6	23065704

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000133477	rs11704416	22	40040969	C	Prostate cancer	23065704	[0.96-1.15]	1.05	EFO_0001663
ENSG00000133477	rs11704416	22	40040969	C	Prostate cancer	23065704	[1.02-1.10]	1.06	EFO_0001663

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000133477's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000133477	FAM83F	100	78.466	ENSAMEG00000011020	FAM83F	99	82.670	Ailuropoda_melanoleuca
ENSG00000133477	FAM83F	98	57.485	ENSAPLG00000009665	FAM83F	98	57.285	Anas_platyrhynchos
ENSG00000133477	FAM83F	100	55.094	ENSACAG00000007387	FAM83F	100	54.631	Anolis_carolinensis
ENSG00000133477	FAM83F	100	84.615	ENSANAG00000027381	FAM83F	100	87.377	Aotus_nancymaae
ENSG00000133477	FAM83F	100	80.157	ENSBTAG00000014247	FAM83F	100	82.122	Bos_taurus
ENSG00000133477	FAM83F	100	86.588	ENSCJAG00000002721	FAM83F	100	86.785	Callithrix_jacchus
ENSG00000133477	FAM83F	100	81.416	ENSCAFG00000001288	FAM83F	100	81.766	Canis_familiaris
ENSG00000133477	FAM83F	99	80.671	ENSCAFG00020002339	FAM83F	98	81.460	Canis_lupus_dingo
ENSG00000133477	FAM83F	100	81.065	ENSCHIG00000026060	FAM83F	100	81.854	Capra_hircus
ENSG00000133477	FAM83F	99	85.772	ENSTSYG00000028609	FAM83F	100	85.772	Carlito_syrichta
ENSG00000133477	FAM83F	100	75.811	ENSCAPG00000004680	FAM83F	100	78.250	Cavia_aperea
ENSG00000133477	FAM83F	100	78.698	ENSCPOG00000014133	FAM83F	100	78.698	Cavia_porcellus
ENSG00000133477	FAM83F	100	86.982	ENSCCAG00000026740	FAM83F	100	88.166	Cebus_capucinus
ENSG00000133477	FAM83F	100	96.208	ENSCATG00000035519	FAM83F	100	96.208	Cercocebus_atys
ENSG00000133477	FAM83F	100	80.512	ENSCLAG00000016721	FAM83F	100	80.512	Chinchilla_lanigera
ENSG00000133477	FAM83F	100	96.407	ENSCSAG00000006058	FAM83F	100	96.407	Chlorocebus_sabaeus
ENSG00000133477	FAM83F	95	82.353	ENSCHOG00000010532	FAM83F	99	83.575	Choloepus_hoffmanni
ENSG00000133477	FAM83F	100	55.664	ENSCPBG00000022941	FAM83F	100	56.055	Chrysemys_picta_bellii
ENSG00000133477	FAM83F	100	95.195	ENSCANG00000030851	FAM83F	100	95.585	Colobus_angolensis_palliatus
ENSG00000133477	FAM83F	100	80.318	ENSCGRG00001018899	Fam83f	100	79.722	Cricetulus_griseus_chok1gshd
ENSG00000133477	FAM83F	100	77.313	ENSCGRG00000016702	Fam83f	100	79.365	Cricetulus_griseus_crigri
ENSG00000133477	FAM83F	100	80.792	ENSDNOG00000046641	FAM83F	100	82.178	Dasypus_novemcinctus
ENSG00000133477	FAM83F	97	77.439	ENSDORG00000013192	Fam83f	97	79.341	Dipodomys_ordii
ENSG00000133477	FAM83F	100	69.231	ENSETEG00000016860	FAM83F	100	72.088	Echinops_telfairi
ENSG00000133477	FAM83F	98	85.944	ENSEASG00005005338	FAM83F	97	86.207	Equus_asinus_asinus
ENSG00000133477	FAM83F	100	84.676	ENSECAG00000009129	FAM83F	100	86.051	Equus_caballus
ENSG00000133477	FAM83F	85	70.526	ENSEEUG00000001255	-	100	70.526	Erinaceus_europaeus
ENSG00000133477	FAM83F	100	80.236	ENSFCAG00000013509	FAM83F	100	81.323	Felis_catus
ENSG00000133477	FAM83F	100	56.000	ENSFALG00000012211	FAM83F	100	56.274	Ficedula_albicollis
ENSG00000133477	FAM83F	100	77.581	ENSFDAG00000006165	FAM83F	100	78.779	Fukomys_damarensis
ENSG00000133477	FAM83F	100	54.943	ENSGALG00000045936	FAM83F	81	54.459	Gallus_gallus
ENSG00000133477	FAM83F	99	55.814	ENSGAGG00000007869	FAM83F	100	57.344	Gopherus_agassizii
ENSG00000133477	FAM83F	100	99.002	ENSGGOG00000006871	FAM83F	100	99.002	Gorilla_gorilla
ENSG00000133477	FAM83F	100	81.262	ENSHGLG00000017812	FAM83F	100	81.854	Heterocephalus_glaber_female
ENSG00000133477	FAM83F	100	79.056	ENSHGLG00100004088	FAM83F	99	81.328	Heterocephalus_glaber_male
ENSG00000133477	FAM83F	95	73.846	ENSSTOG00000023057	FAM83F	85	77.665	Ictidomys_tridecemlineatus
ENSG00000133477	FAM83F	100	81.765	ENSJJAG00000011999	Fam83f	100	81.373	Jaculus_jaculus
ENSG00000133477	FAM83F	61	47.937	ENSLACG00000011004	FAM83F	100	47.678	Latimeria_chalumnae
ENSG00000133477	FAM83F	86	80.974	ENSLAFG00000016675	FAM83F	99	82.093	Loxodonta_africana
ENSG00000133477	FAM83F	100	96.208	ENSMFAG00000002020	FAM83F	100	96.208	Macaca_fascicularis
ENSG00000133477	FAM83F	100	96.407	ENSMMUG00000017166	FAM83F	100	96.407	Macaca_mulatta
ENSG00000133477	FAM83F	100	96.008	ENSMNEG00000033076	FAM83F	100	96.008	Macaca_nemestrina
ENSG00000133477	FAM83F	100	95.495	ENSMLEG00000034781	FAM83F	100	96.296	Mandrillus_leucophaeus
ENSG00000133477	FAM83F	99	55.859	ENSMGAG00000012348	FAM83F	99	55.556	Meleagris_gallopavo
ENSG00000133477	FAM83F	100	79.447	ENSMAUG00000015744	Fam83f	100	78.656	Mesocricetus_auratus
ENSG00000133477	FAM83F	100	84.024	ENSMICG00000016129	FAM83F	100	84.024	Microcebus_murinus
ENSG00000133477	FAM83F	100	77.137	ENSMOCG00000003997	Fam83f	100	77.183	Microtus_ochrogaster
ENSG00000133477	FAM83F	100	62.931	ENSMODG00000008966	-	99	62.396	Monodelphis_domestica
ENSG00000133477	FAM83F	100	79.167	MGP_CAROLIEiJ_G0020042	Fam83f	100	78.770	Mus_caroli
ENSG00000133477	FAM83F	100	79.563	ENSMUSG00000022408	Fam83f	100	79.167	Mus_musculus
ENSG00000133477	FAM83F	100	79.365	MGP_PahariEiJ_G0020044	Fam83f	100	78.770	Mus_pahari
ENSG00000133477	FAM83F	100	79.563	MGP_SPRETEiJ_G0020940	Fam83f	100	79.167	Mus_spretus
ENSG00000133477	FAM83F	98	80.242	ENSMLUG00000015534	FAM83F	99	80.242	Myotis_lucifugus
ENSG00000133477	FAM83F	100	82.937	ENSNGAG00000020952	Fam83f	100	82.937	Nannospalax_galili
ENSG00000133477	FAM83F	100	97.006	ENSNLEG00000015307	FAM83F	100	97.006	Nomascus_leucogenys
ENSG00000133477	FAM83F	92	67.419	ENSMEUG00000004881	-	97	67.937	Notamacropus_eugenii
ENSG00000133477	FAM83F	55	74.825	ENSOPRG00000000702	-	55	79.720	Ochotona_princeps
ENSG00000133477	FAM83F	100	79.051	ENSODEG00000012376	FAM83F	100	79.051	Octodon_degus
ENSG00000133477	FAM83F	99	74.631	ENSOCUG00000014060	FAM83F	99	75.556	Oryctolagus_cuniculus
ENSG00000133477	FAM83F	100	85.119	ENSOGAG00000030522	FAM83F	100	85.119	Otolemur_garnettii
ENSG00000133477	FAM83F	100	75.595	ENSOARG00000017179	FAM83F	93	78.765	Ovis_aries
ENSG00000133477	FAM83F	100	98.498	ENSPPAG00000027631	FAM83F	100	98.871	Pan_paniscus
ENSG00000133477	FAM83F	100	81.409	ENSPPRG00000021618	FAM83F	100	82.387	Panthera_pardus
ENSG00000133477	FAM83F	100	72.566	ENSPTIG00000021999	FAM83F	79	75.490	Panthera_tigris_altaica
ENSG00000133477	FAM83F	100	99.401	ENSPTRG00000014405	FAM83F	100	99.401	Pan_troglodytes
ENSG00000133477	FAM83F	100	95.609	ENSPANG00000016392	FAM83F	100	95.609	Papio_anubis
ENSG00000133477	FAM83F	81	46.939	ENSPSIG00000010230	FAM83F	100	47.619	Pelodiscus_sinensis
ENSG00000133477	FAM83F	100	77.579	ENSPEMG00000010602	Fam83f	100	77.976	Peromyscus_maniculatus_bairdii
ENSG00000133477	FAM83F	100	67.761	ENSPCIG00000020369	FAM83F	100	66.988	Phascolarctos_cinereus
ENSG00000133477	FAM83F	100	96.407	ENSPPYG00000011847	FAM83F	100	96.407	Pongo_abelii
ENSG00000133477	FAM83F	82	87.162	ENSPCAG00000008047	FAM83F	82	87.162	Procavia_capensis
ENSG00000133477	FAM83F	100	86.982	ENSPCOG00000016351	FAM83F	100	86.785	Propithecus_coquereli
ENSG00000133477	FAM83F	100	81.139	ENSPVAG00000004972	FAM83F	100	82.515	Pteropus_vampyrus
ENSG00000133477	FAM83F	100	79.365	ENSRNOG00000018330	Fam83f	100	79.167	Rattus_norvegicus
ENSG00000133477	FAM83F	100	96.008	ENSRBIG00000028821	FAM83F	100	96.008	Rhinopithecus_bieti
ENSG00000133477	FAM83F	100	96.008	ENSRROG00000031286	FAM83F	100	96.008	Rhinopithecus_roxellana
ENSG00000133477	FAM83F	100	83.036	ENSSBOG00000024462	FAM83F	100	86.441	Saimiri_boliviensis_boliviensis
ENSG00000133477	FAM83F	99	62.388	ENSSHAG00000011148	-	100	63.265	Sarcophilus_harrisii
ENSG00000133477	FAM83F	100	57.946	ENSSPUG00000010758	FAM83F	100	58.221	Sphenodon_punctatus
ENSG00000133477	FAM83F	99	79.297	ENSSSCG00000000079	FAM83F	99	80.078	Sus_scrofa
ENSG00000133477	FAM83F	93	59.831	ENSTGUG00000010169	FAM83F	100	59.916	Taeniopygia_guttata
ENSG00000133477	FAM83F	100	80.276	ENSTBEG00000005578	FAM83F	100	80.276	Tupaia_belangeri
ENSG00000133477	FAM83F	99	67.066	ENSTTRG00000011451	-	99	68.142	Tursiops_truncatus
ENSG00000133477	FAM83F	100	79.371	ENSUAMG00000007221	FAM83F	100	81.139	Ursus_americanus

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