EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
ACC	chr18	31355203	Missense_Mutation	novel	L1003V	0.28
ACC	chr18	31338390	Silent	novel	K447K	0.42
ACC	chr18	31354976	Missense_Mutation	novel	I927N	0.63
ACC	chr18	31326941	Missense_Mutation	novel	W51L	0.43
BLCA	chr18	31336552	Missense_Mutation	NA	D402N	0.2
BLCA	chr18	31318151	5'UTR	novel		0.36
BLCA	chr18	31354995	Missense_Mutation	NA	M933I	0.33
BLCA	chr18	31346055	Missense_Mutation	novel	G653R	0.3
BLCA	chr18	31346061	Missense_Mutation	NA	E655Q	0.18
BLCA	chr18	31338355	Missense_Mutation	novel	D436N	0.11
BLCA	chr18	31355007	Silent	novel	L937L	0.09
BLCA	chr18	31354613	Missense_Mutation	novel	T806I	0.75
BLCA	chr18	31328238	Missense_Mutation	NA	G89A	0.18
BLCA	chr18	31336423	Missense_Mutation	NA	H359N	0.17
BLCA	chr18	31346141	Missense_Mutation	NA	M681I	0.47
BLCA	chr18	31336547	Nonsense_Mutation	novel	S400*	0.32
BLCA	chr18	31340000	Silent	novel	L554L	0.14
BRCA	chr18	31354321	Missense_Mutation	novel	D709N	0.07
BRCA	chr18	31354729	Missense_Mutation	NA	D845H	0.43
BRCA	chr18	31354537	Missense_Mutation	NA	E781K	0.18
BRCA	chr18	31318288	5'UTR	novel		0.1
BRCA	chr18	31326951	Silent	rs778383508	F54F	0.23
CESC	chr18	31336582	Missense_Mutation	novel	L412M	0.08
CESC	chr18	31331744	Silent	rs778849751	P187P	0.47
CESC	chr18	31334069	Missense_Mutation	novel	R291T	0.35
CESC	chr18	31346106	Missense_Mutation	NA	Q670E	0.32
CESC	chr18	31333652	Missense_Mutation	novel	S250P	0.31
CESC	chr18	31354990	Missense_Mutation	rs370600690	G932S	0.51
CESC	chr18	31343634	Intron	NA		0.35
CESC	chr18	31343993	Missense_Mutation	NA	S630L	0.18
CESC	chr18	31334014	Splice_Region	rs201123667		0.39
CESC	chr18	31354929	Silent	novel	I911I	0.31
COAD	chr18	31333634	Missense_Mutation	NA	G244C	0.34
COAD	chr18	31340012	Missense_Mutation	NA	F558L	0.3
COAD	chr18	31354365	Silent	rs372254735	I723I	0.36
COAD	chr18	31343816	Intron	novel		0.72
COAD	chr18	31354329	Silent	novel	G711G	0.09
COAD	chr18	31330028	Missense_Mutation	NA	S170Y	0.35
COAD	chr18	31318179	5'UTR	novel		0.35
COAD	chr18	31327000	Missense_Mutation	NA	A71T	0.22
COAD	chr18	31328229	Missense_Mutation	rs770916767	R86H	0.21
COAD	chr18	31343816	Intron	novel		0.58
COAD	chr18	31336374	Missense_Mutation	novel	M342I	0.21
COAD	chr18	31354961	Missense_Mutation	novel	V922A	0.24
COAD	chr18	31355173	Missense_Mutation	novel	G993R	0.1
COAD	chr18	31354973	Missense_Mutation	NA	V926A	0.2
COAD	chr18	31329925	Missense_Mutation	NA	D136Y	0.11
COAD	chr18	31354905	Silent	NA	S903S	0.19
COAD	chr18	31330028	Missense_Mutation	NA	S170Y	0.37
COAD	chr18	31334163	Missense_Mutation	NA	M322I	0.32
COAD	chr18	31326880	Missense_Mutation	NA	D31Y	0.35
COAD	chr18	31346137	Missense_Mutation	rs771756989	S680Y	0.27
COAD	chr18	31343569	In_Frame_Ins	novel	Q603delinsLVVE	0.07
COAD	chr18	31355259	Silent	novel	H1021H	0.11
COAD	chr18	31343816	Intron	novel		0.14
DLBC	chr18	31346139	Missense_Mutation	novel	M681V	0.17
DLBC	chr18	31331733	Missense_Mutation	rs757446872	A184T	0.1
ESCA	chr18	31355076	Silent	rs200560952	G960G	0.8
ESCA	chr18	31354644	Silent	rs772943379	S816S	0.39
ESCA	chr18	31343658	Intron	rs112958941		0.33
ESCA	chr18	31336505	Missense_Mutation	rs557916314	R386H	0.08
GBM	chr18	31343495	Missense_Mutation	rs369362154	R578H	0.39
GBM	chr18	31354701	Silent	NA	V835V	0.15
GBM	chr18	31339796	Frame_Shift_Ins	novel	N488*	0.5
GBM	chr18	31354505	Frame_Shift_Ins	novel	*D770Efs3**	0.08
GBM	chr18	31355103	Silent	rs766364666	G969G	0.42
GBM	chr18	31328229	Missense_Mutation	rs770916767	R86H	0.44
GBM	chr18	31354989	Silent	rs147922509	S931S	0.37
GBM	chr18	31333628	Nonsense_Mutation	NA	R242*	0.36
GBM	chr18	31355410	3'UTR	novel		0.27
HNSC	chr18	31343469	Silent	novel	I569I	0.18
HNSC	chr18	31355161	Missense_Mutation	rs145472309	G989S	0.07
HNSC	chr18	31355329	Missense_Mutation	rs140838956	V1045M	0.26
HNSC	chr18	31339936	Missense_Mutation	novel	G533E	0.11
HNSC	chr18	31334185	Nonsense_Mutation	novel	*I330Kfs6**	0.21
HNSC	chr18	31328324	Missense_Mutation	novel	E118K	0.09
HNSC	chr18	31339886	Frame_Shift_Del	novel	*D516Efs46**	0.3
HNSC	chr18	31343491	Missense_Mutation	novel	P577S	0.23
HNSC	chr18	31354382	Missense_Mutation	novel	P729L	0.37
HNSC	chr18	31334172	Silent	novel	R325R	0.45
HNSC	chr18	31355299	Missense_Mutation	novel	A1035S	0.29
HNSC	chr18	31334127	Missense_Mutation	novel	I310M	0.11
KICH	chr18	31346055	Missense_Mutation	novel	G653R	0.59
KIRC	chr18	31355262	Silent	NA	H1022H	0.23
KIRC	chr18	31354555	Nonsense_Mutation	NA	Q787*	0.11
KIRC	chr18	31318340	Missense_Mutation	NA	I14V	0.39
KIRP	chr18	31355337	Nonsense_Mutation	novel	Y1047*	0.42
KIRP	chr18	31339772	Silent	novel	T478T	0.37
LAML	chr18	31354963	Missense_Mutation	novel	T923P	0.18
LGG	chr18	31333685	Missense_Mutation	novel	D261N	0.17
LGG	chr18	31336481	Missense_Mutation	novel	N378S	0.15
LGG	chr18	31339798	Missense_Mutation	novel	G487D	0.05
LGG	chr18	31343964	Silent	rs548157114	N620N	0.13
LGG	chr18	31355149	Missense_Mutation	NA	G985C	0.29
LGG	chr18	31354776	Silent	NA	S860S	0.09
LGG	chr18	31318269	5'UTR	novel		0.19
LGG	chr18	31355262	Silent	NA	H1022H	0.24
LGG	chr18	31331747	Missense_Mutation	NA	N188K	0.36
LGG	chr18	31355020	Missense_Mutation	rs757887746	E942K	0.08
LIHC	chr18	31343810	Intron	novel		0.45
LIHC	chr18	31354358	Missense_Mutation	rs773377615	Y721C	0.38
LUAD	chr18	31331827	Missense_Mutation	novel	T215N	0.2
LUAD	chr18	31355153	Missense_Mutation	novel	A986D	0.15
LUAD	chr18	31336547	Missense_Mutation	NA	S400L	0.17
LUAD	chr18	31354845	Missense_Mutation	NA	M883I	0.19
LUAD	chr18	31328264	Missense_Mutation	novel	G98R	0.14
LUAD	chr18	31334182	Nonsense_Mutation	NA	G329*	0.13
LUAD	chr18	31336364	Missense_Mutation	NA	Y339C	0.7
LUAD	chr18	31339918	Missense_Mutation	novel	V527E	0.24
LUAD	chr18	31355216	Missense_Mutation	NA	G1007V	0.38
LUAD	chr18	31336601	Missense_Mutation	novel	S418L	0.23
LUAD	chr18	31338323	Missense_Mutation	novel	M425T	0.15
LUAD	chr18	31334202	Missense_Mutation	novel	K335N	0.19
LUAD	chr18	31336373	Missense_Mutation	novel	M342K	0.61
LUAD	chr18	31343654	Intron	novel		0.28
LUAD	chr18	31354803	Silent	novel	V869V	0.2
LUAD	chr18	31331782	Missense_Mutation	NA	R200I	0.25
LUAD	chr18	31343516	Missense_Mutation	NA	P585L	0.14
LUAD	chr18	31326958	Missense_Mutation	NA	A57T	0.18
LUAD	chr18	31338451	Missense_Mutation	novel	D468H	0.12
LUAD	chr18	31354716	Silent	novel	S840S	0.03
LUAD	chr18	31339824	Missense_Mutation	novel	P496A	0.05
LUAD	chr18	31339932	Missense_Mutation	novel	P532T	0.37
LUAD	chr18	31326873	Splice_Site	NA	X29_splice	0.6
LUAD	chr18	31333592	Missense_Mutation	NA	Y230H	0.61
LUAD	chr18	31355247	Silent	NA	S1017S	0.2
LUAD	chr18	31354568	Missense_Mutation	novel	P791H	0.29
LUAD	chr18	31354569	Silent	rs765897238	P791P	0.29
LUAD	chr18	31329964	Missense_Mutation	novel	D149Y	0.06
LUAD	chr18	31328224	Silent	NA	T84T	0.18
LUAD	chr18	31329987	Silent	novel	V156V	0.86
LUAD	chr18	31355419	3'UTR	novel		0.53
LUAD	chr18	31326967	Missense_Mutation	NA	E60K	0.15
LUAD	chr18	31354563	Silent	NA	T789T	0.4
LUAD	chr18	31339771	Missense_Mutation	novel	T478K	0.42
LUAD	chr18	31355169	Silent	NA	L991L	0.07
LUAD	chr18	31326974	Missense_Mutation	novel	E62V	0.32
LUAD	chr18	31354479	Silent	novel	I761I	0.4
LUAD	chr18	31336456	Missense_Mutation	novel	S370T	0.29
LUSC	chr18	31338429	Nonsense_Mutation	NA	Y460*	0.2
LUSC	chr18	31326897	Silent	novel	N36N	0.23
LUSC	chr18	31326600	Missense_Mutation	novel	S23N	0.2
LUSC	chr18	31354766	Missense_Mutation	rs200643856	R857Q	0.43
LUSC	chr18	31339978	Missense_Mutation	novel	G547V	0.54
LUSC	chr18	31333611	Missense_Mutation	NA	A236D	0.17
LUSC	chr18	31354652	Missense_Mutation	novel	G819V	0.15
LUSC	chr18	31343987	Missense_Mutation	rs746988678	D628G	0.26
LUSC	chr18	31343667	Intron	novel		0.69
LUSC	chr18	31354614	Silent	novel	T806T	0.12
LUSC	chr18	31326941	Missense_Mutation	novel	W51L	0.46
LUSC	chr18	31354473	Silent	NA	A759A	0.13
LUSC	chr18	31354342	Missense_Mutation	novel	D716Y	0.41
LUSC	chr18	31343485	Missense_Mutation	NA	G575S	0.14
LUSC	chr18	31355389	3'UTR	novel		0.36
LUSC	chr18	31343964	Silent	rs548157114	N620N	0.46
LUSC	chr18	31355008	Missense_Mutation	NA	S938C	0.38
LUSC	chr18	31354745	Missense_Mutation	novel	S850Y	0.64
LUSC	chr18	31339903	Missense_Mutation	rs772134381	T522S	0.14
LUSC	chr18	31331791	Missense_Mutation	rs770676155	P203L	0.42
LUSC	chr18	31354381	Missense_Mutation	novel	P729T	0.23
LUSC	chr18	31354626	Silent	novel	S810S	0.46
LUSC	chr18	31354574	Missense_Mutation	novel	V793D	0.4
LUSC	chr18	31334077	Missense_Mutation	NA	D294H	0.1
LUSC	chr18	31326615	Missense_Mutation	novel	Q28L	0.42
LUSC	chr18	31343658	Intron	rs112958941		0.16
LUSC	chr18	31354451	Missense_Mutation	NA	G752V	0.33
LUSC	chr18	31339848	Missense_Mutation	novel	T504A	0.32
LUSC	chr18	31328307	Missense_Mutation	novel	T112I	0.24
LUSC	chr18	31343537	Missense_Mutation	NA	G592V	0.54
OV	chr18	31339924	Missense_Mutation	novel	S529C	0.04
OV	chr18	31343518	Missense_Mutation	NA	V586F	0.17
OV	chr18	31338381	Missense_Mutation	novel	L444F	0.07
OV	chr18	31354643	Missense_Mutation	rs372724391	S816L	0.25
OV	chr18	31355373	3'UTR	novel		0.1
OV	chr18	31318304	Missense_Mutation	novel	D2H	0.06
OV	chr18	31333672	Missense_Mutation	NA	N256K	0.38
OV	chr18	31334066	Missense_Mutation	NA	I290N	0.39
OV	chr18	31355153	Missense_Mutation	novel	A986V	0.09
PAAD	chr18	31343657	Intron	NA		0.21
PAAD	chr18	31354855	Nonsense_Mutation	novel	R887*	0.19
PAAD	chr18	31355092	Missense_Mutation	novel	G966C	0.18
PRAD	chr18	31343635	Intron	novel		0.5
PRAD	chr18	31354990	Missense_Mutation	rs370600690	G932S	0.27
READ	chr18	31333594	Silent	rs781133396	Y230Y	0.92
READ	chr18	31339969	Missense_Mutation	novel	V544A	0.1
READ	chr18	31326880	Missense_Mutation	NA	D31Y	0.39
READ	chr18	31326951	Silent	rs778383508	F54F	0.38
READ	chr18	31334171	Missense_Mutation	NA	R325I	0.35
READ	chr18	31354605	Silent	rs747276192	F803F	0.39
READ	chr18	31326951	Silent	rs778383508	F54F	0.35
READ	chr18	31334171	Missense_Mutation	NA	R325I	0.32
SKCM	chr18	31354558	Missense_Mutation	NA	E788K	0.47
SKCM	chr18	31327006	Splice_Site	NA	X72_splice	0.16
SKCM	chr18	31338332	Missense_Mutation	NA	N428I	0.29
SKCM	chr18	31346056	Missense_Mutation	novel	G653E	0.31
SKCM	chr18	31331787	Missense_Mutation	novel	E202K	0.33
SKCM	chr18	31333694	Missense_Mutation	novel	D264N	0.25
SKCM	chr18	31336514	Missense_Mutation	NA	S389L	0.3
SKCM	chr18	31354995	Missense_Mutation	NA	M933I	0.56
SKCM	chr18	31338438	Silent	NA	T463T	0.19
SKCM	chr18	31334141	Missense_Mutation	NA	G315E	0.17
SKCM	chr18	31354732	Missense_Mutation	novel	T846S	0.21
SKCM	chr18	31354733	Missense_Mutation	novel	T846I	0.23
SKCM	chr18	31318243	5'UTR	novel		0.22
SKCM	chr18	31346171	Missense_Mutation	NA	M691I	0.15
SKCM	chr18	31318267	5'UTR	rs367869221		0.76
SKCM	chr18	31338434	Missense_Mutation	rs148956893	G462E	0.1
SKCM	chr18	31346137	Missense_Mutation	NA	S680F	0.35
SKCM	chr18	31334141	Missense_Mutation	NA	G315E	0.12
SKCM	chr18	31326951	Silent	rs778383508	F54F	0.44
SKCM	chr18	31318187	5'UTR	novel		0.18
SKCM	chr18	31336469	Missense_Mutation	NA	V374A	0.19
SKCM	chr18	31318243	5'UTR	novel		0.16
SKCM	chr18	31333712	Missense_Mutation	NA	E270K	0.39
SKCM	chr18	31334082	Silent	NA	L295L	0.23
SKCM	chr18	31355302	Nonsense_Mutation	rs144199555	R1036*	0.31
SKCM	chr18	31318233	5'UTR	rs550343480		0.22
SKCM	chr18	31329992	Missense_Mutation	rs754465552	S158L	0.37
SKCM	chr18	31318279	5'UTR	novel		0.33
SKCM	chr18	31355156	Missense_Mutation	NA	G987E	0.28
SKCM	chr18	31329980	Missense_Mutation	rs760202888	P154L	0.18
SKCM	chr18	31334032	Nonsense_Mutation	NA	Q279*	0.24
SKCM	chr18	31338399	Silent	NA	K450K	0.21
SKCM	chr18	31354670	Missense_Mutation	NA	P825L	0.29
SKCM	chr18	31338326	Missense_Mutation	NA	G426E	0.64
SKCM	chr18	31354759	Missense_Mutation	rs561112685	D855N	0.51
SKCM	chr18	31338367	Missense_Mutation	NA	G440S	0.48
SKCM	chr18	31355216	Missense_Mutation	NA	G1007E	0.36
SKCM	chr18	31334121	Silent	NA	F308F	0.24
SKCM	chr18	31328273	Missense_Mutation	NA	V101I	0.14
SKCM	chr18	31355148	Missense_Mutation	novel	M984I	0.26
SKCM	chr18	31318304	Missense_Mutation	novel	D2N	0.38
SKCM	chr18	31354759	Missense_Mutation	rs561112685	D855N	0.34
SKCM	chr18	31354552	Missense_Mutation	rs267605156	P786S	0.64
SKCM	chr18	31331708	Silent	NA	L175L	0.42
SKCM	chr18	31339810	Missense_Mutation	NA	R491K	0.66
SKCM	chr18	31355440	3'UTR	novel		0.24
SKCM	chr18	31343536	Missense_Mutation	NA	G592R	0.61
SKCM	chr18	31354564	Missense_Mutation	NA	E790K	0.25
SKCM	chr18	31354933	Missense_Mutation	NA	H913Y	0.57
SKCM	chr18	31346074	Missense_Mutation	NA	G659E	0.36
SKCM	chr18	31354994	Missense_Mutation	NA	M933K	0.21
SKCM	chr18	31346161	Missense_Mutation	NA	G688D	0.23
SKCM	chr18	31333702	Silent	NA	I266I	0.1
SKCM	chr18	31355309	Missense_Mutation	rs370813362	R1038Q	0.08
SKCM	chr18	31354663	Missense_Mutation	NA	P823S	0.26
SKCM	chr18	31354866	Silent	rs771323370	S890S	0.71
SKCM	chr18	31354639	Missense_Mutation	rs778980591	P815S	0.07
SKCM	chr18	31318200	5'UTR	novel		0.36
SKCM	chr18	31343466	Missense_Mutation	NA	M568I	0.12
SKCM	chr18	31354328	Missense_Mutation	NA	G711E	0.38
SKCM	chr18	31334141	Missense_Mutation	NA	G315E	0.52
SKCM	chr18	31336423	Missense_Mutation	NA	H359Y	0.23
SKCM	chr18	31343545	Missense_Mutation	NA	H595Y	0.36
SKCM	chr18	31331838	Nonsense_Mutation	rs145081747	R219*	0.27
SKCM	chr18	31355020	Missense_Mutation	rs757887746	E942K	0.27
SKCM	chr18	31354711	Missense_Mutation	rs181411154	E839K	0.33
SKCM	chr18	31318213	5'UTR	novel		0.28
SKCM	chr18	31346177	Silent	NA	F693F	0.31
SKCM	chr18	31333702	Silent	NA	I266I	0.39
SKCM	chr18	31336356	Splice_Region	NA	P336P	0.32
SKCM	chr18	31343567	Missense_Mutation	NA	P602L	0.25
SKCM	chr18	31329902	Missense_Mutation	NA	R128Q	0.15
SKCM	chr18	31354689	Silent	novel	G831G	0.17
SKCM	chr18	31338455	Splice_Site	NA	X469_splice	0.19
SKCM	chr18	31346143	Missense_Mutation	NA	R682K	0.13
SKCM	chr18	31339942	Missense_Mutation	NA	G535E	0.52
SKCM	chr18	31354558	Missense_Mutation	NA	E788K	0.07
SKCM	chr18	31354593	Silent	NA	I799I	0.31
SKCM	chr18	31326999	Silent	rs186238458	I70I	0.11
SKCM	chr18	31331838	Nonsense_Mutation	rs145081747	R219*	0.34
SKCM	chr18	31354487	Missense_Mutation	NA	G764E	0.15
SKCM	chr18	31355249	Missense_Mutation	NA	S1018F	0.42
SKCM	chr18	31354651	Missense_Mutation	novel	G819S	0.77
SKCM	chr18	31354856	Missense_Mutation	rs368044134	R887Q	0.9
SKCM	chr18	31355405	3'UTR	novel		1
SKCM	chr18	31336492	Missense_Mutation	NA	G382S	0.44
SKCM	chr18	31354822	Missense_Mutation	novel	D876N	0.48
SKCM	chr18	31343518	Missense_Mutation	rs373183283	V586I	0.09
SKCM	chr18	31354589	Missense_Mutation	NA	P798Q	0.08
SKCM	chr18	31333702	Silent	NA	I266I	0.28
SKCM	chr18	31354663	Missense_Mutation	NA	P823S	0.44
SKCM	chr18	31333722	Missense_Mutation	NA	S273L	0.18
SKCM	chr18	31334163	Missense_Mutation	NA	M322I	0.11
SKCM	chr18	31340016	Missense_Mutation	NA	V560I	0.28
SKCM	chr18	31334141	Missense_Mutation	NA	G315E	0.27
SKCM	chr18	31343545	Missense_Mutation	NA	H595Y	0.29
SKCM	chr18	31354501	Missense_Mutation	rs371822501	P769S	0.28
SKCM	chr18	31354887	Silent	novel	R897R	0.29
SKCM	chr18	31334141	Missense_Mutation	NA	G315E	0.23
SKCM	chr18	31354513	Missense_Mutation	rs778198305	P773S	0.09
SKCM	chr18	31343571	Silent	novel	Q603Q	0.38
SKCM	chr18	31328321	Nonsense_Mutation	rs755271644	R117*	0.2
SKCM	chr18	31318215	5'UTR	novel		0.29
SKCM	chr18	31329992	Missense_Mutation	rs754465552	S158L	0.15
SKCM	chr18	31354496	Missense_Mutation	NA	S767L	0.24
SKCM	chr18	31346163	Silent	NA	L689L	0.79
SKCM	chr18	31343476	Missense_Mutation	rs137983671	D572N	0.52
SKCM	chr18	31354417	Missense_Mutation	NA	E741K	0.27
SKCM	chr18	31334062	Missense_Mutation	rs377729186	E289K	0.31
SKCM	chr18	31354966	Missense_Mutation	NA	E924K	0.25
SKCM	chr18	31318267	5'UTR	rs367869221		0.12
SKCM	chr18	31334055	Missense_Mutation	rs761869585	N286K	0.29
SKCM	chr18	31328341	Silent	rs138672131	F123F	0.42
SKCM	chr18	31329992	Missense_Mutation	rs754465552	S158L	0.73
SKCM	chr18	31333621	Silent	novel	G239G	0.87
SKCM	chr18	31336381	Silent	novel	L345L	0.77
SKCM	chr18	31355313	Silent	novel	I1039I	0.68
SKCM	chr18	31355421	3'UTR	novel		0.48
SKCM	chr18	31334183	Missense_Mutation	NA	G329E	0.19
STAD	chr18	31334061	Silent	rs760320030	L288L	0.23
STAD	chr18	31333628	Nonsense_Mutation	NA	R242*	0.29
STAD	chr18	31339941	Missense_Mutation	NA	G535R	0.18
STAD	chr18	31334114	Missense_Mutation	rs371165240	V306A	0.35
STAD	chr18	31333594	Silent	rs781133396	Y230Y	0.2
STAD	chr18	31346019	Missense_Mutation	NA	E641K	0.37
STAD	chr18	31354635	Silent	novel	T813T	0.39
STAD	chr18	31338417	Silent	rs150549762	L456L	0.14
STAD	chr18	31355214	Missense_Mutation	novel	L1006F	0.14
STAD	chr18	31326610	Silent	novel	R26R	0.13
STAD	chr18	31318206	5'UTR	novel		0.67
STAD	chr18	31334091	Silent	NA	E298E	0.09
STAD	chr18	31354877	Missense_Mutation	NA	V894G	0.21
THYM	chr18	31336503	Silent	rs768303232	F385F	0.08
UCEC	chr18	31343816	Intron	rs574439712		0.44
UCEC	chr18	31343816	Intron	novel		0.35
UCEC	chr18	31339806	Missense_Mutation	rs750427281	D490N	0.33
UCEC	chr18	31343833	Intron	novel		0.36
UCEC	chr18	31354710	Silent	rs758293574	T838T	0.12
UCEC	chr18	31346109	Nonsense_Mutation	NA	E671*	0.26
UCEC	chr18	31354842	Silent	rs748921617	E882E	0.28
UCEC	chr18	31318187	5'UTR	novel		0.15
UCEC	chr18	31338320	Missense_Mutation	novel	V424A	0.24
UCEC	chr18	31338362	Missense_Mutation	NA	R438I	0.29
UCEC	chr18	31328249	Missense_Mutation	NA	D93N	0.45
UCEC	chr18	31354365	Silent	rs372254735	I723I	0.42
UCEC	chr18	31343816	Intron	novel		0.56
UCEC	chr18	31343739	Intron	novel		0.47
UCEC	chr18	31355440	3'UTR	novel		0.41
UCEC	chr18	31334137	Nonsense_Mutation	novel	E314*	0.29
UCEC	chr18	31333596	Missense_Mutation	rs201719724	G231D	0.37
UCEC	chr18	31354705	Missense_Mutation	rs757641298	V837M	0.4
UCEC	chr18	31354961	Missense_Mutation	novel	V922A	0.47
UCEC	chr18	31330000	Missense_Mutation	novel	T161P	0.17
UCEC	chr18	31339756	Missense_Mutation	novel	R473I	0.1
UCEC	chr18	31354605	Silent	rs747276192	F803F	0.16
UCEC	chr18	31346121	Missense_Mutation	novel	T675A	0.44
UCEC	chr18	31331821	Missense_Mutation	novel	R213I	0.07
UCEC	chr18	31354437	Missense_Mutation	NA	F747L	0.08
UCEC	chr18	31328324	Nonsense_Mutation	NA	E118*	0.2
UCEC	chr18	31354901	Missense_Mutation	novel	S902I	0.09
UCEC	chr18	31339802	Silent	NA	N488N	0.06
UCEC	chr18	31328205	Missense_Mutation	NA	A78D	0.12
UCEC	chr18	31336423	Missense_Mutation	NA	H359Y	0.14
UCEC	chr18	31346099	Missense_Mutation	NA	E667D	0.11
UCEC	chr18	31328206	Silent	novel	A78A	0.1
UCEC	chr18	31333632	Missense_Mutation	novel	D243A	0.16
UCEC	chr18	31334028	Missense_Mutation	novel	E277D	0.2
UCEC	chr18	31343971	Missense_Mutation	novel	I623L	0.43
UCEC	chr18	31343944	Missense_Mutation	rs762460837	P614S	0.41
UCEC	chr18	31330018	Nonsense_Mutation	novel	E167*	0.26
UCEC	chr18	31343651	Intron	novel		0.53
UCEC	chr18	31346128	Missense_Mutation	novel	R677I	0.5
UCEC	chr18	31354662	Missense_Mutation	novel	H822Q	0.38
UCEC	chr18	31334114	Missense_Mutation	rs371165240	V306A	0.34
UCEC	chr18	31343689	Intron	novel		0.35
UCEC	chr18	31339855	Missense_Mutation	novel	R506K	0.44
UCEC	chr18	31329996	Missense_Mutation	novel	M159I	0.29
UCEC	chr18	31336505	Missense_Mutation	rs557916314	R386H	0.2
UCEC	chr18	31339756	Missense_Mutation	novel	R473I	0.45
UCEC	chr18	31326951	Silent	rs778383508	F54F	0.2
UCEC	chr18	31339826	Silent	rs146820029	P496P	0.58
UCEC	chr18	31340018	Silent	novel	V560V	0.35
UCEC	chr18	31346047	Missense_Mutation	novel	R650I	0.36
UCEC	chr18	31343816	Intron	rs574439712		0.55
UCEC	chr18	31326918	Silent	rs753543956	S43S	0.5
UCEC	chr18	31354327	Nonsense_Mutation	NA	G711*	0.38
UCEC	chr18	31355303	Missense_Mutation	rs778003137	R1036Q	0.35
UCEC	chr18	31354605	Silent	rs747276192	F803F	0.52
UCEC	chr18	31333609	Silent	novel	L235L	0.42
UCEC	chr18	31354652	Missense_Mutation	novel	G819D	0.34
UCEC	chr18	31326935	Missense_Mutation	NA	R49H	0.22
UCEC	chr18	31326608	Nonsense_Mutation	rs397515639	R26*	0.16
UCEC	chr18	31334187	Missense_Mutation	novel	I330M	0.24
UCEC	chr18	31339756	Missense_Mutation	novel	R473K	0.2
UCEC	chr18	31355076	Silent	rs200560952	G960G	0.37
UCEC	chr18	31343583	Missense_Mutation	novel	R607S	0.34
UCEC	chr18	31327000	Missense_Mutation	NA	A71T	0.3
UCEC	chr18	31331732	Silent	rs200895473	D183D	0.29
UCEC	chr18	31355303	Missense_Mutation	rs778003137	R1036Q	0.35
UCEC	chr18	31333684	Silent	rs140546771	L260L	0.17
UCEC	chr18	31326912	Nonsense_Mutation	novel	W41*	0.2
UCEC	chr18	31333596	Missense_Mutation	rs201719724	G231D	0.29
UCEC	chr18	31318278	5'UTR	novel		0.05
UCEC	chr18	31343803	Intron	novel		0.33
UCEC	chr18	31331744	Silent	rs778849751	P187P	0.3
UCEC	chr18	31355020	Missense_Mutation	rs757887746	E942K	0.25
UCEC	chr18	31331759	Frame_Shift_Del	novel	I194*	0.38
UCEC	chr18	31343725	Intron	novel		0.15
UCEC	chr18	31354710	Silent	novel	T838T	0.3
UCEC	chr18	31354856	Missense_Mutation	rs368044134	R887Q	0.23
UCEC	chr18	31354971	Missense_Mutation	novel	R925S	0.16
UCEC	chr18	31343816	Intron	novel		0.1
UCEC	chr18	31326951	Silent	rs778383508	F54F	0.65
UCEC	chr18	31331839	Missense_Mutation	rs373006917	R219Q	0.53
UCEC	chr18	31331856	Missense_Mutation	novel	L225I	0.12
UCEC	chr18	31355020	Missense_Mutation	rs757887746	E942K	0.21
UCEC	chr18	31318118	5'UTR	novel		0.19
UCEC	chr18	31318199	5'UTR	novel		0.2
UCEC	chr18	31334152	Nonsense_Mutation	NA	E319*	0.29
UCEC	chr18	31354365	Silent	rs372254735	I723I	0.28
UCEC	chr18	31354492	Nonsense_Mutation	NA	E766*	0.06
UCEC	chr18	31326583	Splice_Region	novel	V17V	0.15
UCEC	chr18	31328258	Missense_Mutation	novel	P96T	0.22
UCEC	chr18	31331732	Silent	rs200895473	D183D	0.2
UCEC	chr18	31355283	Silent	rs755411256	S1029S	0.23
UCEC	chr18	31355440	3'UTR	novel		0.4
UCEC	chr18	31338412	Missense_Mutation	rs367878087	M455V	0.56
UCEC	chr18	31354895	Missense_Mutation	rs761811223	A900E	0.13
UCEC	chr18	31318322	Missense_Mutation	novel	V8I	0.28
UCEC	chr18	31326898	Missense_Mutation	novel	G37S	0.33
UCEC	chr18	31331744	Silent	rs778849751	P187P	0.41
UCEC	chr18	31334121	Missense_Mutation	novel	F308L	0.31
UCEC	chr18	31338367	Missense_Mutation	novel	G440C	0.32
UCEC	chr18	31354458	Missense_Mutation	novel	K754N	0.3
UVM	chr18	31333640	Missense_Mutation	novel	A246T	0.49

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value

Survival Analysis

Cancer	P-value	Q-value
MESO	0.022	Kaplan-Meier Survival Analysis
SKCM	0.00012	Kaplan-Meier Survival Analysis
LUSC	0.049	Kaplan-Meier Survival Analysis
BRCA	0.0065	Kaplan-Meier Survival Analysis
BLCA	0.0015	Kaplan-Meier Survival Analysis
LIHC	0.024	Kaplan-Meier Survival Analysis
LUAD	0.042	Kaplan-Meier Survival Analysis
OV	0.041	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000134760 (Gene tree)
Gene ID: 1828
Gene Symbol: DSG1
Alias: CDHF4|DSG
Full Name: desmoglein 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 41,158 bases
Position: chr18:31,318,089-31,359,246
Accession: 3048
RBP type: non-canonical RBP
Summary: This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
17135055	Pemphigus in the XXI century: new life to an old story.	Autoimmunity	2006 Nov	Grando SA	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000257192	DSG1-201	5045	-	ENSP00000257192	1049 (aa)	-	Q02413
ENST00000462981	DSG1-202	1857	-	ENSP00000462666	408 (aa)	-	Q02413

Gene Model

Click here to download ENSG00000134760's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa05150	Staphylococcus aureus infection	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000134760	Platelet Function Tests	2.0943100E-005	-
ENSG00000134760	Eosinophilic Esophagitis	7E-6	20208534

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000134760	rs7236477	18	31322359	G	Eosinophilic esophagitis (pediatric)	20208534	[1.39-3.55]	2.22	EFO_0004232
ENSG00000134760	rs200520431	18	31338235	?	Yeast infection	28928442	[0.09-0.12] unit increase	0.11	EFO_0008412

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000134760's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000134760	DSG1	99	33.879	ENSG00000046604	DSG2	95	52.727	Homo_sapiens

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001533	cornified envelope	-	TAS	Component
GO:0005509	calcium ion binding	1770008.	NAS	Function
GO:0005515	protein binding	24965446.	IPI	Function
GO:0005829	cytosol	-	TAS	Component
GO:0005886	plasma membrane	-	TAS	Component
GO:0005911	cell-cell junction	7983064.	IDA	Component
GO:0007043	cell-cell junction assembly	12485422.	NAS	Process
GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	-	IEA	Process
GO:0009898	cytoplasmic side of plasma membrane	7983064.	IDA	Component
GO:0015643	toxic substance binding	12582396.	NAS	Function
GO:0016021	integral component of membrane	-	IEA	Component
GO:0016324	apical plasma membrane	-	IEA	Component
GO:0016328	lateral plasma membrane	-	IEA	Component
GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	1770008.	NAS	Process
GO:0030057	desmosome	1711210.	NAS	Component
GO:0031424	keratinization	-	TAS	Process
GO:0032570	response to progesterone	-	IEA	Process
GO:0043312	neutrophil degranulation	-	TAS	Process
GO:0045295	gamma-catenin binding	7983064.	IPI	Function
GO:0050821	protein stabilization	7983064.	IDA	Process
GO:0060135	maternal process involved in female pregnancy	-	IEA	Process
GO:0070268	cornification	-	TAS	Process
GO:0098609	cell-cell adhesion	1711210.	NAS	Process
GO:0101003	ficolin-1-rich granule membrane	-	TAS	Component

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.