EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
27601166	Lower DSC1 expression is related to the poor differentiation and prognosis of head and neck squamous cell carcinoma (HNSCC).	J Cancer Res Clin Oncol	2016 Dec	Wang Y	-
17088906	Desmocollin switching in colorectal cancer.	Br J Cancer	2006 Nov 20	Khan K	-

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
BLCA	chr18	31157420	Missense_Mutation	novel	R101K	0.35
BLCA	chr18	31157548	Silent	NA	S58S	0.32
BLCA	chr18	31157548	Silent	NA	S58S	0.24
BLCA	chr18	31156092	Missense_Mutation	rs773770610	A141D	0.24
BLCA	chr18	31134112	Missense_Mutation	rs538161979	R632H	0.5
BLCA	chr18	31139848	Missense_Mutation	novel	N521K	0.07
BLCA	chr18	31157508	Silent	novel	L72L	0.07
BLCA	chr18	31143711	Missense_Mutation	novel	I340M	0.44
BLCA	chr18	31131489	Intron	novel		0.56
BLCA	chr18	31157548	Silent	NA	S58S	0.13
BLCA	chr18	31140144	Missense_Mutation	NA	P473L	0.46
BLCA	chr18	31157550	Missense_Mutation	novel	S58A	0.31
BLCA	chr18	31130815	Intron	novel		0.25
BLCA	chr18	31148500	Missense_Mutation	NA	S257F	0.33
BLCA	chr18	31130421	3'UTR	novel		0.35
BLCA	chr18	31140168	Missense_Mutation	novel	S465I	0.43
BRCA	chr18	31134106	Missense_Mutation	rs762966345	R634Q	0.41
BRCA	chr18	31142018	Missense_Mutation	NA	G414E	0.13
BRCA	chr18	31157557	Missense_Mutation	novel	C55W	0.11
BRCA	chr18	31162536	Missense_Mutation	NA	L20P	0.45
BRCA	chr18	31145661	Missense_Mutation	novel	H297Y	0.48
CESC	chr18	31130377	3'UTR	novel		0.43
CESC	chr18	31157473	Silent	rs765140793	L83L	0.22
CESC	chr18	31162562	Silent	novel	I11I	0.27
CESC	chr18	31130627	Missense_Mutation	NA	L858V	0.31
CESC	chr18	31134019	Missense_Mutation	rs199628832	R663T	0.26
CESC	chr18	31131700	Missense_Mutation	novel	G794V	0.49
CESC	chr18	31162629	5'UTR	novel		0.16
CHOL	chr18	31130792	Intron	novel		0.61
COAD	chr18	31156087	Silent	rs749005269	L143L	0.1
COAD	chr18	31132653	Missense_Mutation	novel	R718I	0.31
COAD	chr18	31142064	Nonsense_Mutation	novel	E399*	0.1
COAD	chr18	31148561	Missense_Mutation	novel	D237Y	0.32
COAD	chr18	31157430	Missense_Mutation	NA	D98Y	0.18
COAD	chr18	31131855	Intron	novel		0.24
COAD	chr18	31130673	Silent	rs139389841	H842H	0.34
COAD	chr18	31130660	Missense_Mutation	rs771621552	V847I	0.39
COAD	chr18	31143751	Missense_Mutation	novel	M327T	0.18
COAD	chr18	31156123	Missense_Mutation	rs759805213	R131C	0.41
COAD	chr18	31139785	Frame_Shift_Ins	NA	*N542Kfs28**	0.32
COAD	chr18	31131904	Intron	novel		0.74
COAD	chr18	31131768	Silent	novel	G771G	0.51
COAD	chr18	31132390	Intron	novel		0.14
COAD	chr18	31134074	Missense_Mutation	rs770181232	P645S	0.33
COAD	chr18	31140097	Nonsense_Mutation	NA	E489*	0.24
COAD	chr18	31142165	Missense_Mutation	NA	E365A	0.23
COAD	chr18	31143787	Missense_Mutation	NA	C315Y	0.31
DLBC	chr18	31162620	5'UTR	rs751892388		0.33
DLBC	chr18	31145678	Missense_Mutation	novel	P291Q	0.1
ESCA	chr18	31131612	Silent	novel	T823T	0.41
GBM	chr18	31156052	Silent	NA	H154H	0.43
GBM	chr18	31143665	Missense_Mutation	NA	E356K	0.39
GBM	chr18	31132653	Missense_Mutation	novel	R718I	0.07
GBM	chr18	31133979	Missense_Mutation	NA	K676N	0.17
GBM	chr18	31140246	Missense_Mutation	novel	E439A	0.18
GBM	chr18	31145777	Missense_Mutation	novel	G258V	0.22
GBM	chr18	31130492	3'UTR	novel		0.09
GBM	chr18	31132639	Missense_Mutation	NA	C723S	0.27
GBM	chr18	31131596	Missense_Mutation	rs774457500	E829K	0.58
GBM	chr18	31134131	Splice_Site	novel	X626_splice	0.35
GBM	chr18	31156073	Silent	rs374138359	S147S	0.08
GBM	chr18	31132644	Missense_Mutation	novel	K721R	0.32
GBM	chr18	31156111	Nonsense_Mutation	rs773655264	R135*	0.28
GBM	chr18	31131717	Silent	novel	T788T	0.15
HNSC	chr18	31140125	Missense_Mutation	novel	Q479H	0.34
HNSC	chr18	31157424	Missense_Mutation	novel	Q100E	0.08
HNSC	chr18	31145658	Missense_Mutation	novel	P298A	0.09
HNSC	chr18	31131470	Intron	novel		0.25
HNSC	chr18	31133921	Missense_Mutation	novel	A696S	0.48
KIRC	chr18	31140293	Silent	NA	N423N	0.07
KIRP	chr18	31132649	Silent	novel	T719T	0.36
LAML	chr18	31156096	Missense_Mutation	novel	P140T	0.04
LGG	chr18	31145740	Silent	rs758162064	D270D	0.08
LGG	chr18	31140097	Missense_Mutation	novel	E489K	0.38
LGG	chr18	31145685	Missense_Mutation	NA	D289Y	0.32
LGG	chr18	31159486	Missense_Mutation	NA	R36P	0.43
LIHC	chr18	31139886	Nonsense_Mutation	NA	Q509*	0.39
LIHC	chr18	31140176	Silent	novel	I462I	0.17
LIHC	chr18	31140208	Missense_Mutation	novel	T452A	0.39
LIHC	chr18	31131941	Intron	novel		0.22
LUAD	chr18	31132436	Intron	novel		0.46
LUAD	chr18	31139745	Splice_Region	novel		0.29
LUAD	chr18	31154791	Nonsense_Mutation	novel	K204*	0.24
LUAD	chr18	31134779	Silent	NA	R557R	0.13
LUAD	chr18	31131695	Missense_Mutation	NA	G796R	0.29
LUAD	chr18	31145736	Missense_Mutation	novel	P272T	0.07
LUAD	chr18	31156116	Missense_Mutation	rs761035986	K133R	0.3
LUAD	chr18	31134020	Nonsense_Mutation	NA	R663*	0.27
LUAD	chr18	31134781	Missense_Mutation	NA	G556A	0.1
LUAD	chr18	31139755	Silent	novel	V552V	0.3
LUAD	chr18	31142039	Missense_Mutation	novel	T407K	0.39
LUAD	chr18	31154929	Missense_Mutation	NA	I158F	0.1
LUAD	chr18	31157556	Missense_Mutation	NA	L56I	0.09
LUAD	chr18	31157554	Silent	rs758140282	L56L	0.08
LUAD	chr18	31156073	Silent	NA	S147S	0.28
LUAD	chr18	31139760	Missense_Mutation	NA	A551S	0.61
LUAD	chr18	31134728	Missense_Mutation	NA	A574S	0.37
LUAD	chr18	31140070	Missense_Mutation	rs758323245	P498S	0.17
LUAD	chr18	31148602	Missense_Mutation	NA	E223V	0.16
LUAD	chr18	31130673	Silent	rs139389841	H842H	0.48
LUAD	chr18	31131669	Silent	NA	K804K	0.51
LUAD	chr18	31131709	Missense_Mutation	rs754301512	S791F	0.28
LUAD	chr18	31130615	Missense_Mutation	novel	V862L	0.51
LUAD	chr18	31143774	Frame_Shift_Ins	novel	*L320Vfs17**	0.11
LUSC	chr18	31142010	Missense_Mutation	rs372473569	C417R	0.23
LUSC	chr18	31157523	Missense_Mutation	novel	P67T	0.57
LUSC	chr18	31157524	Missense_Mutation	novel	D66E	0.57
LUSC	chr18	31145679	Missense_Mutation	novel	P291A	0.12
LUSC	chr18	31131637	Missense_Mutation	novel	A815E	0.33
LUSC	chr18	31132584	Missense_Mutation	NA	P741H	0.3
LUSC	chr18	31130562	Missense_Mutation	rs754100664	H879Q	0.26
LUSC	chr18	31148632	Missense_Mutation	novel	Y213S	0.08
LUSC	chr18	31134046	Missense_Mutation	novel	L654S	0.09
LUSC	chr18	31132684	Missense_Mutation	novel	L708V	0.46
LUSC	chr18	31130570	Missense_Mutation	NA	L877I	0.06
LUSC	chr18	31133993	Missense_Mutation	NA	E672Q	0.43
LUSC	chr18	31143755	Missense_Mutation	NA	D326N	0.33
LUSC	chr18	31142090	Missense_Mutation	novel	A390V	0.25
LUSC	chr18	31131764	Nonsense_Mutation	novel	G773*	0.21
LUSC	chr18	31162660	5'UTR	novel		0.21
LUSC	chr18	31162687	5'UTR	novel		0.18
OV	chr18	31134079	Missense_Mutation	NA	S643F	0.22
OV	chr18	31134576	Missense_Mutation	NA	K624N	0.16
OV	chr18	31139747	Splice_Site	NA	X553_splice	0.15
OV	chr18	31154838	Missense_Mutation	rs757507124	E188G	0.39
OV	chr18	31134735	Missense_Mutation	rs376495489	N571K	0.21
OV	chr18	31132605	Missense_Mutation	NA	I734T	0.49
PAAD	chr18	31130596	Missense_Mutation	novel	R868P	0.07
PAAD	chr18	31145703	Frame_Shift_Del	novel	*I283Sfs38**	0.23
PAAD	chr18	31130519	Missense_Mutation	novel	K894Q	0.2
PAAD	chr18	31145628	Missense_Mutation	rs369709593	P308S	0.17
PAAD	chr18	31143660	Silent	novel	T357T	0.09
PRAD	chr18	31139890	Missense_Mutation	novel	R507S	0.39
PRAD	chr18	31134074	Missense_Mutation	rs770181232	P645S	0.45
READ	chr18	31131781	Missense_Mutation	rs781031026	G767D	0.14
READ	chr18	31134710	Nonsense_Mutation	NA	E580*	0.23
READ	chr18	31131596	Missense_Mutation	rs774457500	E829K	0.07
READ	chr18	31133945	Missense_Mutation	NA	I688L	0.35
SARC	chr18	31130411	3'UTR	novel		0.67
SKCM	chr18	31145713	Silent	NA	L279L	0.25
SKCM	chr18	31130833	Intron	novel		0.19
SKCM	chr18	31139871	Missense_Mutation	novel	E514K	0.34
SKCM	chr18	31130666	Missense_Mutation	NA	D845N	0.42
SKCM	chr18	31145765	Missense_Mutation	NA	G262E	0.3
SKCM	chr18	31157455	Silent	NA	R89R	0.42
SKCM	chr18	31131701	Missense_Mutation	NA	G794R	0.37
SKCM	chr18	31140144	Missense_Mutation	NA	P473L	0.27
SKCM	chr18	31133978	Missense_Mutation	rs267605150	D677N	0.35
SKCM	chr18	31143703	Missense_Mutation	novel	S343L	0.35
SKCM	chr18	31142119	Silent	NA	Q380Q	0.38
SKCM	chr18	31131528	Intron	novel		0.32
SKCM	chr18	31131740	Missense_Mutation	novel	E781K	0.41
SKCM	chr18	31156115	Silent	rs762795811	K133K	0.44
SKCM	chr18	31162541	Silent	novel	F18F	0.37
SKCM	chr18	31130440	3'UTR	novel		0.43
SKCM	chr18	31157455	Silent	NA	R89R	0.43
SKCM	chr18	31139871	Missense_Mutation	novel	E514K	0.19
SKCM	chr18	31140098	Missense_Mutation	novel	Q488H	0.39
SKCM	chr18	31140067	Missense_Mutation	novel	E499K	0.45
SKCM	chr18	31143673	Missense_Mutation	NA	S353F	0.44
SKCM	chr18	31148573	Missense_Mutation	NA	E233K	0.25
SKCM	chr18	31132587	Missense_Mutation	novel	G740E	0.21
SKCM	chr18	31157437	Silent	rs770260276	F95F	0.23
SKCM	chr18	31140296	Silent	novel	L422L	0.25
SKCM	chr18	31159511	Missense_Mutation	rs778060935	D28N	0.27
SKCM	chr18	31131596	Missense_Mutation	rs774457500	E829K	0.21
SKCM	chr18	31131903	Intron	novel		0.14
SKCM	chr18	31134113	Missense_Mutation	rs766289899	R632C	0.29
SKCM	chr18	31134621	Silent	NA	F609F	0.16
SKCM	chr18	31142149	Silent	NA	V370V	0.17
SKCM	chr18	31145668	Silent	NA	F294F	0.08
SKCM	chr18	31156102	Missense_Mutation	NA	P138S	0.37
SKCM	chr18	31131519	Intron	novel		0.44
SKCM	chr18	31130617	Missense_Mutation	NA	S861L	0.95
SKCM	chr18	31145766	Missense_Mutation	NA	G262R	0.52
SKCM	chr18	31157430	Missense_Mutation	NA	D98N	0.36
SKCM	chr18	31140234	Missense_Mutation	NA	S443F	0.25
SKCM	chr18	31157460	Missense_Mutation	NA	E88K	0.28
SKCM	chr18	31131656	Missense_Mutation	NA	G809R	0.18
SKCM	chr18	31131657	Silent	novel	Q808Q	0.17
SKCM	chr18	31157455	Silent	NA	R89R	0.39
SKCM	chr18	31159487	Nonsense_Mutation	rs765867185	R36*	0.41
SKCM	chr18	31142119	Silent	NA	Q380Q	0.46
SKCM	chr18	31162647	5'UTR	novel		0.42
SKCM	chr18	31143695	Missense_Mutation	NA	D346N	0.3
SKCM	chr18	31157437	Silent	rs770260276	F95F	0.45
SKCM	chr18	31131501	Intron	novel		0.58
SKCM	chr18	31132684	Silent	NA	L708L	0.79
SKCM	chr18	31156066	Missense_Mutation	NA	P150S	0.32
SKCM	chr18	31130446	3'UTR	novel		0.39
SKCM	chr18	31132421	Intron	novel		0.42
SKCM	chr18	31130833	Intron	novel		0.24
SKCM	chr18	31157455	Silent	NA	R89R	0.52
SKCM	chr18	31148591	Missense_Mutation	NA	P227S	0.33
SKCM	chr18	31130833	Intron	novel		0.14
SKCM	chr18	31131862	Intron	novel		0.14
SKCM	chr18	31148524	Missense_Mutation	NA	F249Y	0.09
SKCM	chr18	31156159	Missense_Mutation	rs780041445	P119S	0.21
SKCM	chr18	31156060	Missense_Mutation	NA	P152S	0.23
SKCM	chr18	31132621	Missense_Mutation	NA	A729T	0.33
SKCM	chr18	31145641	Silent	NA	I303I	0.35
SKCM	chr18	31145745	Missense_Mutation	NA	L269F	0.46
SKCM	chr18	31143680	Missense_Mutation	novel	P351S	0.36
SKCM	chr18	31148567	Missense_Mutation	rs267605152	D235N	0.37
SKCM	chr18	31157456	Missense_Mutation	NA	R89K	0.36
SKCM	chr18	31130633	Missense_Mutation	NA	G856S	0.27
SKCM	chr18	31145682	Missense_Mutation	NA	H290Y	0.41
SKCM	chr18	31157455	Silent	NA	R89R	0.38
SKCM	chr18	31142064	Missense_Mutation	NA	E399K	0.37
SKCM	chr18	31130471	3'UTR	novel		0.49
SKCM	chr18	31131656	Missense_Mutation	NA	G809R	0.24
SKCM	chr18	31134626	Nonsense_Mutation	NA	Q608*	0.31
SKCM	chr18	31142069	Missense_Mutation	NA	G397E	0.65
SKCM	chr18	31131605	Missense_Mutation	rs201513884	R826W	0.1
SKCM	chr18	31159481	Missense_Mutation	NA	P38S	0.07
SKCM	chr18	31132588	Missense_Mutation	NA	G740R	0.2
SKCM	chr18	31154785	Missense_Mutation	rs769698282	E206K	0.22
SKCM	chr18	31130591	Missense_Mutation	NA	E870K	0.29
SKCM	chr18	31143735	Silent	rs371108741	F332F	0.42
SKCM	chr18	31133916	Missense_Mutation	novel	M697I	0.61
SKCM	chr18	31134752	Missense_Mutation	NA	H566Y	0.22
SKCM	chr18	31130583	Silent	rs758525190	E872E	0.17
SKCM	chr18	31140236	Silent	NA	F442F	0.18
SKCM	chr18	31139872	Missense_Mutation	NA	D513E	0.39
SKCM	chr18	31142103	Missense_Mutation	NA	P386S	0.74
SKCM	chr18	31131708	Silent	NA	S791S	0.35
SKCM	chr18	31159489	Missense_Mutation	novel	L35R	0.14
SKCM	chr18	31143764	Missense_Mutation	NA	E323K	0.35
SKCM	chr18	31131708	Silent	NA	S791S	0.37
SKCM	chr18	31130591	Missense_Mutation	NA	E870K	0.19
SKCM	chr18	31133939	Missense_Mutation	novel	G690R	0.37
SKCM	chr18	31130597	Missense_Mutation	rs201568166	R868W	0.16
SKCM	chr18	31145627	Missense_Mutation	NA	P308L	0.39
SKCM	chr18	31145627	Missense_Mutation	NA	P308L	0.34
SKCM	chr18	31140154	Missense_Mutation	NA	E470K	0.12
SKCM	chr18	31162559	Silent	NA	F12F	0.27
SKCM	chr18	31139886	Nonsense_Mutation	NA	Q509*	0.13
SKCM	chr18	31140110	Silent	NA	F484F	0.15
SKCM	chr18	31134573	Missense_Mutation	novel	D625E	0.3
SKCM	chr18	31134627	Silent	novel	F607F	0.06
SKCM	chr18	31132633	Missense_Mutation	rs769486740	P725S	0.26
SKCM	chr18	31148543	Missense_Mutation	NA	E243K	0.38
SKCM	chr18	31131585	Intron	novel		0.28
SKCM	chr18	31134669	Silent	NA	L593L	0.43
SKCM	chr18	31133998	Missense_Mutation	NA	P670L	0.22
SKCM	chr18	31131668	Missense_Mutation	NA	G805R	0.1
SKCM	chr18	31134057	Missense_Mutation	novel	D650E	0.42
SKCM	chr18	31134059	Missense_Mutation	novel	D650N	0.43
SKCM	chr18	31145613	Missense_Mutation	NA	E313K	0.36
SKCM	chr18	31134614	Missense_Mutation	rs774520872	D612N	0.36
SKCM	chr18	31142064	Missense_Mutation	NA	E399K	0.41
SKCM	chr18	31157455	Silent	NA	R89R	0.3
SKCM	chr18	31139868	Missense_Mutation	rs763321997	D515N	0.21
SKCM	chr18	31134655	Missense_Mutation	novel	P598L	0.29
SKCM	chr18	31148567	Missense_Mutation	rs267605152	D235N	0.44
SKCM	chr18	31131825	Silent	rs765807646	L752L	0.37
SKCM	chr18	31145778	Splice_Site	novel	X258_splice	0.75
SKCM	chr18	31131615	Silent	novel	F822F	0.38
SKCM	chr18	31131808	Missense_Mutation	NA	N758S	0.27
SKCM	chr18	31132403	Intron	novel		0.46
SKCM	chr18	31139801	Missense_Mutation	NA	S537F	0.57
SKCM	chr18	31156074	Missense_Mutation	rs745670805	S147L	0.6
SKCM	chr18	31134686	Missense_Mutation	NA	E588K	0.5
SKCM	chr18	31133998	Missense_Mutation	NA	P670L	0.52
STAD	chr18	31154872	Missense_Mutation	rs780160984	V177M	0.3
STAD	chr18	31131675	Silent	rs770954271	S802S	0.05
STAD	chr18	31148613	Silent	NA	G219G	0.31
STAD	chr18	31162624	5'UTR	novel		0.46
STAD	chr18	31140243	Missense_Mutation	novel	A440E	0.17
STAD	chr18	31156116	Missense_Mutation	rs761035986	K133R	0.18
STAD	chr18	31130463	3'UTR	novel		0.04
STAD	chr18	31130554	Missense_Mutation	NA	P882H	0.04
STAD	chr18	31130653	Missense_Mutation	rs754736071	S849L	0.25
STAD	chr18	31140100	Missense_Mutation	novel	Q488K	0.36
STAD	chr18	31130613	Silent	NA	V862V	0.29
STAD	chr18	31131934	Intron	novel		0.27
STAD	chr18	31134728	Missense_Mutation	rs777889677	A574T	0.22
THYM	chr18	31142013	Silent	rs757940347	L416L	0.06
UCEC	chr18	31134778	Missense_Mutation	rs760068759	R557Q	0.26
UCEC	chr18	31148556	Silent	rs756999312	N238N	0.34
UCEC	chr18	31156111	Nonsense_Mutation	rs773655264	R135*	0.32
UCEC	chr18	31131677	Missense_Mutation	novel	S802P	0.32
UCEC	chr18	31134100	Missense_Mutation	novel	N636T	0.34
UCEC	chr18	31145674	Missense_Mutation	novel	K292N	0.35
UCEC	chr18	31148556	Silent	rs756999312	N238N	0.33
UCEC	chr18	31154863	Nonsense_Mutation	NA	E180*	0.21
UCEC	chr18	31157461	Silent	novel	S87S	0.49
UCEC	chr18	31145739	Missense_Mutation	NA	E271K	0.42
UCEC	chr18	31130494	3'UTR	novel		0.46
UCEC	chr18	31134728	Missense_Mutation	rs777889677	A574T	0.32
UCEC	chr18	31134706	Missense_Mutation	NA	V581A	0.44
UCEC	chr18	31140225	Missense_Mutation	rs770773404	A446V	0.43
UCEC	chr18	31130553	Silent	novel	P882P	0.51
UCEC	chr18	31142042	Missense_Mutation	novel	S406N	0.11
UCEC	chr18	31132477	Intron	novel		0.46
UCEC	chr18	31131747	Missense_Mutation	novel	Q778H	0.41
UCEC	chr18	31131929	Intron	novel		0.42
UCEC	chr18	31145754	Missense_Mutation	NA	A266T	0.39
UCEC	chr18	31143704	Frame_Shift_Del	novel	*S343Hfs21**	0.17
UCEC	chr18	31131643	Missense_Mutation	NA	R813K	0.14
UCEC	chr18	31140303	Splice_Site	NA	X421_splice	0.2
UCEC	chr18	31142146	Missense_Mutation	NA	E371D	0.05
UCEC	chr18	31131904	Intron	novel		0.38
UCEC	chr18	31148555	Missense_Mutation	NA	A239T	0.11
UCEC	chr18	31131608	Missense_Mutation	novel	P825S	0.22
UCEC	chr18	31145629	Silent	novel	T307T	0.2
UCEC	chr18	31130596	Missense_Mutation	NA	R868Q	0.45
UCEC	chr18	31143734	Missense_Mutation	rs150991775	G333S	0.4
UCEC	chr18	31132457	Intron	novel		0.49
UCEC	chr18	31140236	Missense_Mutation	novel	F442L	0.11
UCEC	chr18	31142138	Missense_Mutation	novel	R374Q	0.08
UCEC	chr18	31145739	Missense_Mutation	NA	E271K	0.33
UCEC	chr18	31162584	Missense_Mutation	novel	A4D	0.13
UCEC	chr18	31130532	Missense_Mutation	rs761297633	K889N	0.31
UCEC	chr18	31134663	Silent	novel	P595P	0.22
UCEC	chr18	31134728	Missense_Mutation	rs777889677	A574T	0.41
UCEC	chr18	31157430	Missense_Mutation	NA	D98N	0.38
UCEC	chr18	31132486	Intron	novel		0.41
UCEC	chr18	31162653	5'UTR	novel		0.31
UCEC	chr18	31154863	Nonsense_Mutation	NA	E180*	0.38
UCEC	chr18	31145720	Missense_Mutation	NA	T277S	0.42
UCEC	chr18	31133952	Silent	novel	P685P	0.5
UCEC	chr18	31154796	Missense_Mutation	rs773035285	R202H	0.41
UCEC	chr18	31159486	Missense_Mutation	NA	R36Q	0.64
UCEC	chr18	31156051	Missense_Mutation	rs150722381	V155I	0.38
UCEC	chr18	31157414	Missense_Mutation	novel	E103G	0.11
UCEC	chr18	31131966	Intron	novel		0.38
UCEC	chr18	31134757	Missense_Mutation	rs774153969	V564A	0.37
UCEC	chr18	31134059	Missense_Mutation	novel	D650N	0.21
UCEC	chr18	31143789	Missense_Mutation	novel	K314N	0.24
UCEC	chr18	31154833	Missense_Mutation	novel	D190Y	0.09
UCEC	chr18	31133969	Missense_Mutation	novel	T680A	0.27
UCEC	chr18	31148634	Silent	novel	G212G	0.4
UCEC	chr18	31134658	Missense_Mutation	novel	D597G	0.13
UCEC	chr18	31132421	Intron	novel		0.06
UCEC	chr18	31132602	Missense_Mutation	novel	V735A	0.37
UCEC	chr18	31143748	Missense_Mutation	novel	G328D	0.34
UCEC	chr18	31145622	Missense_Mutation	novel	L310M	0.41
UCEC	chr18	31159511	Missense_Mutation	rs778060935	D28N	0.28
UCEC	chr18	31140114	Missense_Mutation	rs769086731	G483D	0.29
UCEC	chr18	31130361	3'UTR	novel		0.45
UCEC	chr18	31132365	Intron	novel		0.31
UCEC	chr18	31134621	Silent	NA	F609F	0.44
UCEC	chr18	31154775	Missense_Mutation	rs115895313	A209V	0.31
UCEC	chr18	31130420	3'UTR	novel		0.13
UCEC	chr18	31130520	Missense_Mutation	novel	K893N	0.35
UCEC	chr18	31139805	Nonsense_Mutation	NA	E536*	0.22
UCEC	chr18	31140153	Missense_Mutation	NA	E470A	0.27
UCEC	chr18	31132460	Intron	novel		0.17
UCEC	chr18	31134582	Missense_Mutation	novel	E622D	0.26
UCEC	chr18	31134772	Missense_Mutation	novel	C559Y	0.24
UCEC	chr18	31162626	5'UTR	novel		0.16
UCEC	chr18	31131636	Silent	rs755652280	A815A	0.24
UCEC	chr18	31145666	Missense_Mutation	novel	S295Y	0.29
UCEC	chr18	31132612	Missense_Mutation	NA	N732D	0.12
UCEC	chr18	31148528	Missense_Mutation	NA	I248L	0.41
UCEC	chr18	31134675	Silent	novel	A591A	0.09
UCEC	chr18	31148503	Missense_Mutation	rs374935177	R256Q	0.08
UCEC	chr18	31131771	Silent	novel	G770G	0.16
UCEC	chr18	31134780	Silent	novel	G556G	0.44
UCEC	chr18	31159486	Missense_Mutation	NA	R36Q	0.17
UCEC	chr18	31131905	Intron	novel		0.41
UCEC	chr18	31142146	Missense_Mutation	NA	E371D	0.31
UCEC	chr18	31156046	Silent	NA	Q156Q	0.27
UCEC	chr18	31130521	Missense_Mutation	NA	K893R	0.37
UCEC	chr18	31154773	Splice_Site	novel	X209_splice	0.38
UCEC	chr18	31133943	Missense_Mutation	novel	I688M	0.25
UCEC	chr18	31134728	Missense_Mutation	rs777889677	A574T	0.35
UCEC	chr18	31157481	Missense_Mutation	novel	H81Y	0.39
UCS	chr18	31140048	Missense_Mutation	novel	G505V	0.28
UCS	chr18	31134637	Missense_Mutation	novel	G604E	0.2
UVM	chr18	31132611	Frame_Shift_Del	novel	*N732Ifs2**	0.37

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0044	Kaplan-Meier Survival Analysis
MESO	0.01	Kaplan-Meier Survival Analysis
SKCM	0.0028	Kaplan-Meier Survival Analysis
BLCA	0.00062	Kaplan-Meier Survival Analysis
LAML	0.00017	Kaplan-Meier Survival Analysis
KICH	0.015	Kaplan-Meier Survival Analysis
LIHC	0.036	Kaplan-Meier Survival Analysis
THCA	0.041	Kaplan-Meier Survival Analysis
LUAD	0.0021	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000134765 (Gene tree)
Gene ID: 1823
Gene Symbol: DSC1
Alias: CDHF1
Full Name: desmocollin 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 33,621 bases
Position: chr18:31,129,236-31,162,856
Accession: 3035
RBP type: non-canonical RBP
Summary: The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. A subtype of IgA pemphigus, a life-threatening autoimmune disease, is characterized by the presence of autoantibodies that target the encoded protein. The desmosomal family members are arranged in two clusters on chromosome 18. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protein. [provided by RefSeq, Nov 2015]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000257198	DSC1-202	4225	-	ENSP00000257198	894 (aa)	-	Q08554
ENST00000257197	DSC1-201	4271	-	ENSP00000257197	840 (aa)	-	Q08554

Gene Model

Click here to download ENSG00000134765's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000134765	Platelet Function Tests	1.3380000E-005	-
ENSG00000134765	Platelet Function Tests	1.2440700E-005	-
ENSG00000134765	Platelet Function Tests	6.5892770E-006	-
ENSG00000134765	Liver Cirrhosis, Biliary	1.4100000E-005	20639880
ENSG00000134765	Multiple Sclerosis	1E-6	23412934

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000134765's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000134765	DSC1	88	31.039	ENSG00000046604	DSG2	88	40.865	Homo_sapiens

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001533	cornified envelope	-	TAS	Component
GO:0005509	calcium ion binding	-	IEA	Function
GO:0005886	plasma membrane	-	TAS	Component
GO:0005921	gap junction	7679953.	TAS	Component
GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	-	IEA	Process
GO:0016020	membrane	7679953.	TAS	Component
GO:0016021	integral component of membrane	-	IEA	Component
GO:0030057	desmosome	-	IEA	Component
GO:0031424	keratinization	-	TAS	Process
GO:0043312	neutrophil degranulation	-	TAS	Process
GO:0070062	extracellular exosome	23533145.	HDA	Component
GO:0070268	cornification	-	TAS	Process
GO:0101003	ficolin-1-rich granule membrane	-	TAS	Component

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.