EuRBPDB

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TCGA tumor abbreviations
  • ACCAdrenocortical carcinoma
  • BLCABladder Urothelial Carcinoma
  • BRCABreast invasive carcinoma
  • CESCCervical squamous cell carcinoma and endocervical adenocarcinoma
  • CHOLCholangio carcinoma
  • COADColon adenocarcinoma
  • DLBCLymphoid Neoplasm Diffuse Large B-cell Lymphoma
  • ESCAEsophageal carcinoma
  • GBMGlioblastoma multiforme
  • HNSCHead and Neck squamous cell carcinoma
  • KICHKidney Chromophobe
  • KIRCKidney renal clear cell carcinoma
  • KIRPKidney renal papillary cell carcinoma
  • LAMLAcute Myeloid Leukemia
  • LGGBrain Lower Grade Glioma
  • LIHCLiver hepatocellular carcinoma
  • LUADLung adenocarcinoma
  • LUSCLung squamous cell carcinoma
  • MESOMesothelioma
  • OVOvarian serous cystadenocarcinoma
  • PAADPancreatic adenocarcinoma
  • PCPGPheochromocytoma and Paraganglioma
  • PRADProstate adenocarcinoma
  • READRectum adenocarcinoma
  • SARCSarcoma
  • SKCMSkin Cutaneous Melanoma
  • STADStomach adenocarcinoma
  • TGCTThyroid carcinoma
  • THCAThyroid carcinoma
  • THYMThymoma
  • UCECUterine Corpus Endometrial Carcinoma
  • UCSUterine Carcinosarcoma
  • UVMUveal Melanoma

Note: Click here to get the extension of tumor abbreviations.


  • Cancer Related Information
  • Basic Information

Cancer associated literatures
PIDTitleArticle TimeAuthorDoi
24452324Musashi-1 expression and clinicopathological significance in young gastric cancer patients: a matched case-control study.Int J Oncol2014 AprChoi JEdoi: 10.3892/ijo.2014.2263
20727204Musashi1 regulates breast tumor cell proliferation and is a prognostic indicator of poor survival.Mol Cancer2010 Aug 21Wang XYdoi: 10.1186/1476-4598-9-221.
19258308Genomic analyses of musashi1 downstream targets show a strong association with cancer-related processes.J Biol Chem2009 May 1de Sousa Abreu Rdoi: 10.1074/jbc.M809605200
25394506Downregulation of Msi1 suppresses the growth of human colon cancer by targeting p21cip1.Int J Oncol2015 FebGao Cdoi: 10.3892/ijo.2014.2749
25362645Msi1 promotes tumor growth and cell proliferation by targeting cell cycle checkpoint proteins p21, p27 and p53 in cervical carcinomas.Oncotarget2014 Nov 15Liu X-
19714342Expression of putative stem cell genes Musashi-1 and beta1-integrin in human colorectal adenomas and adenocarcinomas.Int J Colorectal Dis2010 JanFan LFdoi: 10.1007/s00384-009-0791-2
24163304Clinicopathological sex- related relevance of musashi1 mRNA expression in esophageal squamous cell carcinoma patients.Pathol Oncol Res2014 AprMoghbeli Mdoi: 10.1007/s12253-013-9712-3
25940441Tumor suppressive microRNA-137 negatively regulates Musashi-1 and colorectal cancer progression.Oncotarget2015 May 20Smith AR-
21881409The oncogenic RNA-binding protein Musashi1 is regulated by tumor suppressor miRNAs.RNA Biol2011 Sep-OctVo DTdoi: 10.4161/rna.8.5.16041
23715514Musashi1 as a potential therapeutic target and diagnostic marker for lung cancer.Oncotarget2013 MayWang XY-
26673327The Msi Family of RNA-Binding Proteins Function Redundantly as Intestinal Oncoproteins.Cell Rep2015 Dec 22Li Ndoi: 10.1016/j.celrep.2015.11.022
26563371miR-761 inhibits tumor progression by targeting MSI1 in ovarian carcinoma.Tumour Biol2016 AprShi Cdoi: 10.1007/s13277-015-4377-z
18826648Musashi1 modulates cell proliferation genes in the medulloblastoma cell line Daoy.BMC Cancer2008 Sep 30Sanchez-Diaz PCdoi: 10.1186/1471-2407-8-280.
21829201Sequential expression of putative stem cell markers in gastric carcinogenesis.Br J Cancer2011 Aug 23Wang Tdoi: 10.1038/bjc.2011.287
12054577Expression of the Musashi1 gene encoding the RNA-binding protein in human hepatoma cell lines.Biochem Biophys Res Commun2002 Apr 26Shu HJ-
23164718MSI1 overexpression in diffuse type of gastric cancer.Pathol Res Pract2013 Jan 15Nikpour Pdoi: 10.1016/j.prp.2012.09.008
24787949Cancer stem cell marker Musashi-1 rs2522137 genotype is associated with an increased risk of lung cancer.PLoS One2014 May 2Wang Xdoi: 10.1371/journal.pone.0095915
24525742NOTCH3 signaling regulates MUSASHI-1 expression in metastatic colorectal cancer cells.Cancer Res2014 Apr 1Past?? Adoi: 10.1158/0008-5472.CAN-13-2022
27281208Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma.Nature2016 Jun 16Fox RGdoi: 10.1038/nature17988
18471519Knockdown of RNA binding protein musashi-1 leads to tumor regression in vivo.Gastroenterology2008 MaySureban SMdoi: 10.1053/j.gastro.2008.02.057
21442350Msi-1 is a predictor of survival and a novel therapeutic target in colon cancer.Ann Surg Oncol2011 JulLi Ddoi: 10.1245/s10434-011-1567-9
24151393Expression and significance of Musashi-1 in gastric cancer and precancerous lesions.World J Gastroenterol2013 Oct 21Kuang RGdoi: 10.3748/wjg.v19.i39.6637.
29141252Musashi1 Promotes Non-Small Cell Lung Carcinoma Malignancy and Chemoresistance via Activating the Akt Signaling Pathway.Cell Physiol Biochem2017Lang Ydoi: 10.1159/000485012
28143872Musashi RNA-Binding Proteins as Cancer Drivers and Novel Therapeutic Targets.Clin Cancer Res2017 May 1Kudinov AEdoi: 10.1158/1078-0432.CCR-16-2728
28713964Musashi1, a potential prognostic marker in esophageal squamous cell carcinoma.Oncol Rep2017 SepQin Gdoi: 10.3892/or.2017.5809
29486283Musashi-1 promotes chemoresistant granule formation by PKR/eIF2α signalling cascade in refractory glioblastoma.Biochim Biophys Acta Mol Basis Dis2018 MayChen HYdoi: 10.1016/j.bbadis.2018.02.017
30097032Natural product derivative Gossypolone inhibits Musashi family of RNA-binding proteins.BMC Cancer2018 Aug 10Lan Ldoi: 10.1186/s12885-018-4704-z.

Differential Expression

Expression in 33 cancers

Mutations
CancerChrPosition Mutation TypedbSNPProtein-change Allele FreqRBD
BRCAchr121203414933'UTRrs5523468000.17
BRCAchr12120353347Missense_MutationNAS229R0.53
BRCAchr12120356937Missense_MutationnovelG206E0.2
BRCAchr12120356980Missense_MutationNAP192S0.12
CESCchr12120353343Missense_MutationnovelR230L0.47
CESCchr121203417793'UTRnovel0.69
CESCchr12120363067SilentNAK126K0.19
CESCchr121203417893'UTRnovel0.46
CESCchr12120368253Missense_MutationnovelG41S0.15
CESCchr12120363083Missense_Mutationrs149956156T121M0.15
CESCchr12120351372Silentrs766149013P254P0.53
COADchr12120346306Silentrs756975620T292T0.32
COADchr12120357882Silentrs555470172T156T0.36
COADchr12120364725Missense_MutationNAA100T0.34RRM_1
COADchr12120368039Missense_MutationnovelA79V0.32RRM_1
COADchr12120346251Missense_MutationnovelT311A0.26
COADchr12120353367Missense_MutationnovelF222Y0.15
COADchr12120356993Missense_MutationNAK187N0.31
COADchr12120346295Frame_Shift_DelNAP296Lfs*570.11
COADchr12120364739Missense_MutationnovelA95V0.18RRM_1
ESCAchr12120357863Missense_MutationnovelV163M0.29
ESCAchr12120347474Silentrs561139090A277A0.14
ESCAchr121203419183'UTRrs5340892260.15
ESCAchr12120368073Missense_MutationnovelF68V0.27RRM_1
GBMchr12120353303SilentnovelF243F0.14
GBMchr12120363063Missense_MutationnovelY128H0.04
HNSCchr12120356960Silentrs757303115G198G0.18
HNSCchr12120351373Missense_MutationNAP254Q0.08
KIRCchr12120368058Missense_MutationNAG73R0.31RRM_1
KIRCchr12120353300Splice_Regionrs140182426P244P0.39
KIRPchr12120357844Missense_MutationnovelI169N0.2
LAMLchr12120364747SilentnovelP92P0.05
LGGchr12120353331Missense_MutationnovelG234V0.42
LUADchr12120363091SilentNAV118V0.32
LUADchr121203455843'UTRnovel0.23
LUADchr12120363079SilentnovelV122V0.11
LUSCchr12120347449Missense_MutationnovelT286S0.5
LUSCchr12120363101Missense_MutationnovelG115V0.1
LUSCchr12120347514Missense_MutationnovelA264V0.51
LUSCchr12120351345Splice_RegionnovelT263T0.26
LUSCchr12120364752Missense_MutationNAD91N0.27RRM_1
PAADchr12120345598Missense_MutationnovelY361S0.15
PRADchr12120353354SilentNAT226T0.25
SARCchr121203419433'UTRnovel0.13
SARCchr121203424013'UTRnovel0.48
SKCMchr12120353366SilentnovelF222F0.29
SKCMchr12120345630Splice_Regionrs769474281G350G0.15
SKCMchr12120346321Splice_RegionNAG287G0.86
SKCMchr12120351384SilentnovelR250R0.5
SKCMchr12120353303SilentnovelF243F0.28
SKCMchr12120357008Silentrs367765145K182K0.33
SKCMchr12120363116Missense_MutationnovelK110M0.53
SKCMchr12120356901Splice_SiteNAX218_splice0.09
SKCMchr12120356933Missense_Mutationrs769508876M207I0.26
SKCMchr12120353348SilentNAA228A0.22
STADchr12120346202Missense_MutationnovelS327L0.4
STADchr12120357813Splice_Regionnovel0.25
STADchr12120357826Missense_MutationNAN175S0.35
STADchr12120345599Missense_MutationNAY361H0.08
STADchr12120363100Frame_Shift_DelnovelL116Cfs*30.31
STADchr12120356910Missense_MutationnovelG215D0.06
THCAchr12120364730Missense_MutationNAR98Q0.33RRM_1
THCAchr12120357005Missense_MutationNAK183N0.12
THCAchr12120368079Missense_MutationnovelV66F0.53RRM_1
THCAchr12120368081Frame_Shift_DelnovelF65Sfs*410.5RRM_1
UCECchr121203414983'UTRnovel0.26
UCECchr121203418053'UTRnovel0.41
UCECchr12120345630Splice_Regionrs769474281G350G0.27
UCECchr12120363126Nonsense_MutationNAR107*0.16RRM_1
UCECchr121203421913'UTRnovel0.27
UCECchr12120347494Missense_Mutationrs761676109G271R0.21
UCECchr121203422403'UTRnovel0.75
UCECchr121203420343'UTRnovel0.29
UCECchr121203424403'UTRnovel0.5
UCECchr121203425973'UTRnovel0.17
UCECchr121203420783'UTRnovel0.37
UCECchr12120363083Missense_Mutationrs149956156T121M0.35
UCECchr121203423673'UTRnovel0.58
UCECchr12120363095Missense_MutationnovelS117L0.57
UCECchr121203413853'UTRnovel0.31
UCECchr121203420403'UTRnovel0.33
UCECchr121203425313'UTRrs7576366360.33
UCECchr12120346178Missense_MutationnovelA335V0.29
UCECchr12120353300Splice_Regionrs140182426P244P0.32
UCECchr121203420393'UTRnovel0.35
UCECchr12120351344Missense_MutationnovelA264T0.62
UCECchr12120347468Silentrs751007952A279A0.35
UCECchr12120347468Silentrs751007952A279A0.27
UCECchr121203416873'UTRnovel0.36
UCECchr121203419833'UTRnovel0.37

Copy Number Variations (CNVs)
CancerTypeFreq Q-value
BRCADEL0.16026.3933e-07
CHOLDEL0.19440.067545
HNSCDEL0.05360.22646
LUADDEL0.14340.0059643
LUSCDEL0.10580.038823
PAADDEL0.17390.0030251
PRADAMP0.05690.016187
SKCMDEL0.17980.00079981

Survival Analysis
CancerP-value Q-value
ACC0.028

Kaplan-Meier Survival Analysis

KIRP0.00042

Kaplan-Meier Survival Analysis

PAAD0.00084

Kaplan-Meier Survival Analysis

LAML0.02

Kaplan-Meier Survival Analysis

KICH0.0073

Kaplan-Meier Survival Analysis

LIHC0.036

Kaplan-Meier Survival Analysis

LGG0.00052

Kaplan-Meier Survival Analysis

THCA0.028

Kaplan-Meier Survival Analysis

LUAD0.047

Kaplan-Meier Survival Analysis

OV0.045

Kaplan-Meier Survival Analysis

Drugs

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Eesembl ID



Cell lines and drugs in GSE70138 or GSE92742

  • Description
  • RBDs
  • RBPome
  • Literatures
  • Expression
  • Transcripts
  • Gene Model
  • Pathways
  • Phenotypes
  • PPI
  • Paralogs
  • Orthologs
  • Gene Ontology
Description
Ensembl ID
ENSG00000135097 (Gene tree)
Gene ID
4440
Gene Symbol
MSI1
Alias
N
Full Name
musashi RNA binding protein 1
Gene Type
protein_coding
Species
Homo_sapiens
Status
confidence
Strand
Minus strand
Length
29,531 bases
Position
chr12:120,339,650-120,369,180
Accession
7330
RBP type
canonical RBP
Summary
This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13. [provided by RefSeq, Jul 2008]
RNA binding domains(RBDs)
Protein IDDomain Pfam IDE-value Domain number Total number
ENSP00000257552RRM_1PF00076.222.1e-3312
ENSP00000257552RRM_1PF00076.222.1e-3322
ENSP00000446710RRM_1PF00076.225e-1511
RNA binding proteome (RBPome)
PIDTitleMethod TimeAuthorDoi
22681889The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts4SURIC & HEK2932012 MayBaltz AGDOI: 10.1016/j.molcel.2012.05.021
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & HEK2932018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004

Literatures on RNA binding capacity
PIDTitleArticle TimeAuthorDoi
22140116Structure of Musashi1 in a complex with target RNA: the role of aromatic stacking interactions.Nucleic Acids Res2012 AprOhyama Tdoi: 10.1093/nar/gkr1139
10080895Structure, backbone dynamics and interactions with RNA of the C-terminal RNA-binding domain of a mouse neural RNA-binding protein, Musashi1.J Mol Biol1999 Mar 26Nagata T-
9334405Expression of neural RNA-binding proteins in the postnatal CNS: implications of their roles in neuronal and glial cell development.J Neurosci1997 Nov 1Sakakibara S-
25362645Msi1 promotes tumor growth and cell proliferation by targeting cell cycle checkpoint proteins p21, p27 and p53 in cervical carcinomas.Oncotarget2014 Nov 15Liu X-
25750985Identification and validation of novel small molecule disruptors of HuR-mRNA interaction.ACS Chem Biol2015 Jun 19Wu Xdoi: 10.1021/cb500851u
29113163Knockdown of MSI1 inhibited the cell proliferation of human osteosarcoma cells by targeting p21 and p27.Oncol Lett2017 NovNiu Jdoi: 10.3892/ol.2017.6870
29290973Human oncoprotein Musashi-2 N-terminal RNA recognition motif backbone assignment and identification of RNA-binding pocket.Oncotarget2017 Nov 20Lan Ldoi: 10.18632/oncotarget.22540
12907678Origin of higher affinity to RNA of the N-terminal RNA-binding domain than that of the C-terminal one of a mouse neural protein, musashi1, as revealed by comparison of their structures, modes of interaction, surface electrostatic potentials, and backbone dynamics.J Biol Chem2003 Oct 17Miyanoiri Y-
12093154Regulation of tau RNA maturation by thyroid hormone is mediated by the neural RNA-binding protein musashi-1.Mol Cell Neurosci2002 JunCuadrado A-
25933687Natural product (-)-gossypol inhibits colon cancer cell growth by targeting RNA-binding protein Musashi-1.Mol Oncol2015 AugLan Ldoi: 10.1016/j.molonc.2015.03.014
28808919Backbone and side chain assignments of the second RNA-binding domain of Musashi-1 in its free form and in complex with 5-mer RNA.Biomol NMR Assign2017 OctIwaoka Rdoi: 10.1007/s12104-017-9760-9
195735293'-Untranslated region of doublecortin mRNA is a binding target of the Musashi1 RNA-binding protein.FEBS Lett2009 Jul 21Horisawa Kdoi: 10.1016/j.febslet.2009.06.045
22264285Post-transcriptional regulation of fukutin in an astrocytoma cell line.Int J Exp Pathol2012 FebYamamoto Tdoi: 10.1111/j.1365-2613.2011.00799.x.
23776146Specificity factors in cytoplasmic polyadenylation.Wiley Interdiscip Rev RNA2013 Jul-AugCharlesworth Adoi: 10.1002/wrna.1171.
9790759The human Musashi homolog 1 (MSI1) gene encoding the homologue of Musashi/Nrp-1, a neural RNA-binding protein putatively expressed in CNS stem cells and neural progenitor cells.Genomics1998 Sep 15Good P-
16554442A role for the ELAV RNA-binding proteins in neural stem cells: stabilization of Msi1 mRNA.J Cell Sci2006 Apr 1Ratti A-
12799417Thyroid hormone-upregulated expression of Musashi-1 is specific for progenitor cells of the adult epithelium during amphibian gastrointestinal remodeling.J Cell Sci2003 Aug 1Ishizuya-Oka A-
12560091Candidate markers for stem and early progenitor cells, Musashi-1 and Hes1, are expressed in crypt base columnar cells of mouse small intestine.FEBS Lett2003 Jan 30Kayahara T-
12558601Identification of a putative intestinal stem cell and early lineage marker; musashi-1.Differentiation2003 JanPotten CS-
12205668Differential expression of Musashi1 and nestin in the adult rat hippocampus after ischemia.J Neurosci Res2002 Sep 15Yagita Y-
12054577Expression of the Musashi1 gene encoding the RNA-binding protein in human hepatoma cell lines.Biochem Biophys Res Commun2002 Apr 26Shu HJ-
11804968RNA binding protein Musashi1 is expressed in sertoli cells in the rat testis from fetal life to adulthood.Biol Reprod2002 FebSaunders PT-
11686236Musashi1, an evolutionarily conserved neural RNA-binding protein, is a versatile marker of human glioma cells in determining their cellular origin, malignancy, and proliferative activity.Differentiation2001 SepKanemura Y-
11588182Rna-binding protein Musashi2: developmentally regulated expression in neural precursor cells and subpopulations of neurons in mammalian CNS.J Neurosci2001 Oct 15Sakakibara S-
11359897The neural RNA-binding protein Musashi1 translationally regulates mammalian numb gene expression by interacting with its mRNA.Mol Cell Biol2001 JunImai T-
11284014Expression of the neural RNA-binding protein Musashi1 in human gliomas.Glia2001 Apr 1Toda M-
11122376MSI-1, a neural RNA-binding protein, is involved in male mating behaviour in Caenorhabditis elegans.Genes Cells2000 NovYoda A-
10657706Musashi1: an evolutionally conserved marker for CNS progenitor cells including neural stem cells.Dev Neurosci2000Kaneko Y-
16287482Correlation between Musashi-1 and c-hairy-1 expression and cell proliferation activity in the developing intestine and stomach of both chicken and mouse.Dev Growth Differ2005 OctAsai R-
16214366The RNA-binding protein Musashi-1 regulates neural development through the translational repression of p21WAF-1.Mol Cell Neurosci2006 JanBattelli C-
16100006Long-term proliferation of human embryonic stem cell-derived neuroepithelial cells using defined adherent culture conditions.Stem Cells2006 JanShin S-
16106215Ectopic expression of Musashi-1 in Alzheimer disease and Pick disease.J Neuropathol Exp Neurol2005 AugLovell MA-
15925591Function of RNA-binding protein Musashi-1 in stem cells.Exp Cell Res2005 Jun 10Okano H-
15076722Spatiotemporal patterns of Musashi1 expression during inner ear development.Neuroreport2004 Apr 29Sakaguchi H-
14700731Expression of Musashi1, a neural RNA-binding protein, in the cochlea of young adult mice.Neurosci Lett2004 Jan 16Murata J-
23412423What is the clinical value of cancer stem cell markers in gliomas?Int J Clin Exp Pathol2013Dahlrot RH-
23418578The effects of Hedgehog on the RNA-binding protein Msi1 in the proliferation and apoptosis of mesenchymal stem cells.PLoS One2013Hong ISdoi: 10.1371/journal.pone.0056496
23132814Musashi1-CreER(T2) : a new cre line for conditional mutagenesis in neural stem cells.Genesis2013 FebTakeda Hdoi: 10.1002/dvg.22357
20036290Musashi1 as a marker of reactive astrocytes after transient focal brain ischemia.Neurosci Res2010 AprOki Kdoi: 10.1016/j.neures.2009.12.013
19645571Positional specification in a neural stem cell line involves modulation of Musashi1 expression.Stem Cells Dev2010 AprMorgan SCdoi: 10.1089/scd.2009.0108.
19551478Expression of a putative stem cell marker, Musashi 1, in mammary glands of ewes.J Mol Histol2009 AprColitti Mdoi: 10.1007/s10735-009-9224-3
19258308Genomic analyses of musashi1 downstream targets show a strong association with cancer-related processes.J Biol Chem2009 May 1de Sousa Abreu Rdoi: 10.1074/jbc.M809605200
19214660Musashi-1 suppresses expression of Paneth cell-specific genes in human intestinal epithelial cells.J Gastroenterol2009Murayama Mdoi: 10.1007/s00535-008-2284-4
19028551Immunohistochemical analysis of Musashi-1 expression during retinal regeneration of adult newt.Neurosci Lett2009 Feb 6Kaneko Jdoi: 10.1016/j.neulet.2008.11.031
22985791The RNA-binding protein Musashi1 affects medulloblastoma growth via a network of cancer-related genes and is an indicator of poor prognosis.Am J Pathol2012 NovVo DTdoi: 10.1016/j.ajpath.2012.07.031
18826648Musashi1 modulates cell proliferation genes in the medulloblastoma cell line Daoy.BMC Cancer2008 Sep 30Sanchez-Diaz PCdoi: 10.1186/1471-2407-8-280.
18719393Musashi1: a stem cell marker no longer in search of a function.Cell Cycle2008 Sep 1Glazer RI-
18662689Musashi-1, an RNA-binding protein, is indispensable for survival of photoreceptors.Exp Eye Res2009 MarSusaki Kdoi: 10.1016/j.exer.2008.06.019
18473332Increased expression of the adult stem cell marker Musashi-1 in endometriosis and endometrial carcinoma.J Pathol2008 JulGotte Mdoi: 10.1002/path.2364.
18490513Neural RNA-binding protein Musashi1 inhibits translation initiation by competing with eIF4G for PABP.J Cell Biol2008 May 19Kawahara Hdoi: 10.1083/jcb.200708004.
18471519Knockdown of RNA binding protein musashi-1 leads to tumor regression in vivo.Gastroenterology2008 MaySureban SMdoi: 10.1053/j.gastro.2008.02.057
18362162Musashi1 modulates mammary progenitor cell expansion through proliferin-mediated activation of the Wnt and Notch pathways.Mol Cell Biol2008 JunWang XYdoi: 10.1128/MCB.00040-08
18098125Musashi1 RNA-binding protein regulates oligodendrocyte lineage cell differentiation and survival.Glia2008 FebDobson NR-
17768378The RNA-binding protein Musashi-1 is produced in the developing and adult mouse eye.Mol Vis2007 Aug 10Raji B-
17627143Expression of the Neural RNA-binding protein Musashi1 in pediatric brain tumors.Pediatr Neurosurg2007Nakano A-
17549630Helicobacter pylori infection induces candidate stem cell marker Musashi-1 in the human gastric epithelium.Dig Dis Sci2008 FebMurata H-
17238803Augmented therapeutic efficacy of an oncolytic herpes simplex virus type 1 mutant expressing ICP34.5 under the transcriptional control of musashi1 promoter in the treatment of malignant glioma.Hum Gene Ther2007 JanKanai R-
16944023Investigation of Musashi-1 expressing cells in the murine model of dextran sodium sulfate-induced colitis.Dig Dis Sci2006 JulFukui T-
16955534Enhanced therapeutic efficacy of oncolytic herpes vector G207 against human non-small cell lung cancer--expression of an RNA-binding protein, Musashi1, as a marker for the tailored gene therapy.J Gene Med2006 NovKanai R-
22428049RNA-binding protein Musashi1 modulates glioma cell growth through the post-transcriptional regulation of Notch and PI3 kinase/Akt signaling pathways.PLoS One2012Muto Jdoi: 10.1371/journal.pone.0033431
22429745Characterization of the RNA-binding protein Musashi1 in zebrafish.Brain Res2012 Jun 26Shibata Sdoi: 10.1016/j.brainres.2012.01.068
22258704The oncogenic RNA-binding protein Musashi1 is regulated by HuR via mRNA translation and stability in glioblastoma cells.Mol Cancer Res2012 JanVo DTdoi: 10.1158/1541-7786.MCR-11-0208.
22201732Musashi1: an RBP with versatile functions in normal and cancer stem cells.Front Biosci (Landmark Ed)2012 Jan 1Glazer RI-
23308249Musashi-1 post-transcriptionally enhances phosphotyrosine-binding domain-containing m-Numb protein expression in regenerating gastric mucosa.PLoS One2013Takahashi Tdoi: 10.1371/journal.pone.0053540
21881409The oncogenic RNA-binding protein Musashi1 is regulated by tumor suppressor miRNAs.RNA Biol2011 Sep-OctVo DTdoi: 10.4161/rna.8.5.16041
21766416Translational control in germ cell development: A role for the RNA-binding proteins Musashi-1 and Musashi-2.IUBMB Life2011 SepGunter KMdoi: 10.1002/iub.499
21486496Identification of a novel intronic enhancer responsible for the transcriptional regulation of musashi1 in neural stem/progenitor cells.Mol Brain2011 Apr 13Kawase Sdoi: 10.1186/1756-6606-4-14.
21442350Msi-1 is a predictor of survival and a novel therapeutic target in colon cancer.Ann Surg Oncol2011 JulLi Ddoi: 10.1245/s10434-011-1567-9
21378162Musashi1 cooperates in abnormal cell lineage protein 28 (Lin28)-mediated let-7 family microRNA biogenesis in early neural differentiation.J Biol Chem2011 May 6Kawahara Hdoi: 10.1074/jbc.M110.199166
21322018The effect of drug treatment on neurogenesis in Parkinson's disease.Mov Disord2011 JanO'Sullivan SSdoi: 10.1002/mds.23340
21165952The adult stem cell marker Musashi-1 modulates endometrial carcinoma cell cycle progression and apoptosis via Notch-1 and p21WAF1/CIP1.Int J Cancer2011 Oct 15Gotte Mdoi: 10.1002/ijc.25856
23209605Drosophila Rbp6 is an orthologue of vertebrate Msi-1 and Msi-2, but does not function redundantly with dMsi to regulate germline stem cell behaviour.PLoS One2012Siddall NAdoi: 10.1371/journal.pone.0049810
20826465The overexpression of the putative gut stem cell marker Musashi-1 induces tumorigenesis through Wnt and Notch activation.J Cell Sci2010 Oct 1Rezza Adoi: 10.1242/jcs.065284
20727204Musashi1 regulates breast tumor cell proliferation and is a prognostic indicator of poor survival.Mol Cancer2010 Aug 21Wang XYdoi: 10.1186/1476-4598-9-221.
20696379Neural RNA-binding protein Musashi1 controls midline crossing of precerebellar neurons through posttranscriptional regulation of Robo3/Rig-1 expression.Neuron2010 Aug 12Kuwako Kdoi: 10.1016/j.neuron.2010.07.005.
20477901The RNA binding protein Musashi1 regulates apoptosis, gene expression and stress granule formation in urothelial carcinoma cells.J Cell Mol Med2011 MayNikpour Pdoi: 10.1111/j.1582-4934.2010.01090.x
20394675Expression of the RNA-binding protein Musashi1 in adult liver stem-like cells.Hepatol Res2010 AprHattori Edoi: 10.1111/j.1872-034X.2009.00612.x.
25483045Mir-23a and mir-125b regulate neural stem/progenitor cell proliferation by targeting Musashi1.RNA Biol2014Gioia Udoi: 10.4161/rna.35508.
25394506Downregulation of Msi1 suppresses the growth of human colon cancer by targeting p21cip1.Int J Oncol2015 FebGao Cdoi: 10.3892/ijo.2014.2749
25283629The prognostic value of clinical factors and cancer stem cell-related markers in gliomas.Dan Med J2014 OctDahlrot RH-
25058468Regulatory factor X transcription factors control Musashi1 transcription in mouse neural stem/progenitor cells.Stem Cells Dev2014 Sep 15Kawase Sdoi: 10.1089/scd.2014.0219.
24935936Allosteric inhibition of a stem cell RNA-binding protein by an intermediary metabolite.Elife2014 Jun 16Clingman CCdoi: 10.7554/eLife.02848.
24671879Developmental expression of Musashi-1 and Musashi-2 RNA-binding proteins during spermatogenesis: analysis of the deleterious effects of dysregulated expression.Biol Reprod2014 May 1Sutherland JMdoi: 10.1095/biolreprod.113.115261
24630719Forgetting is regulated via Musashi-mediated translational control of the Arp2/3 complex.Cell2014 Mar 13Hadziselimovic Ndoi: 10.1016/j.cell.2014.01.054.
24608801RNA binding protein-mediated post-transcriptional gene regulation in medulloblastoma.Mol Cells2014 MayBish Rdoi: 10.14348/molcells.2014.0008
24444033Musashi1 regulates survival of hepatoma cell lines by activation of Wnt signalling pathway.Liver Int2015 MarChen Kdoi: 10.1111/liv.12458
24163304Clinicopathological sex- related relevance of musashi1 mRNA expression in esophageal squamous cell carcinoma patients.Pathol Oncol Res2014 AprMoghbeli Mdoi: 10.1007/s12253-013-9712-3
24057325Prognostic value of Musashi-1 in gliomas.J Neurooncol2013 DecDahlrot RHdoi: 10.1007/s11060-013-1246-8
24022895The RNA-binding protein Musashi-1 regulates proteasome subunit expression in breast cancer- and glioma-initiating cells.Stem Cells2014 JanLagadec Cdoi: 10.1002/stem.1537.
24002004MSI2 expression is decreased in grade II of gastric carcinoma.Pathol Res Pract2013 NovEmadi-Baygi Mdoi: 10.1016/j.prp.2013.07.008
23914149The RNA-Binding Protein Musashi1: A Major Player in Intestinal Epithelium Renewal and Colon Cancer Development.Curr Colorectal Cancer Rep2012Plateroti M-
23880227The effects of hedgehog on RNA binding protein Msi1 during the osteogenic differentiation of human cord blood-derived mesenchymal stem cells.Bone2013 OctHong ISdoi: 10.1016/j.bone.2013.07.016
27285760Musashi-1 regulates AKT-derived IL-6 autocrinal/paracrinal malignancy and chemoresistance in glioblastoma.Oncotarget2016 Jul 5Chen HYdoi: 10.18632/oncotarget.9890.
23712573Brief report: musashi1-eGFP mice, a new tool for differential isolation of the intestinal stem cell populations.Stem Cells2013 OctMaria Cambuli Fdoi: 10.1002/stem.1428.
26303183A Mouse Model of Targeted Musashi1 Expression in Whole Intestinal Epithelium Suggests Regulatory Roles in Cell Cycle and Stemness.Stem Cells2015 DecCambuli FMdoi: 10.1002/stem.2202
27129280RNA-binding Protein Musashi Homologue 1 Regulates Kidney Fibrosis by Translational Inhibition of p21 and Numb mRNA.J Biol Chem2016 Jul 1Jadhav Sdoi: 10.1074/jbc.M115.713289
27470713Musashi1 Impacts Radio-Resistance in Glioblastoma by Controlling DNA-Protein Kinase Catalytic Subunit.Am J Pathol2016 Sepde Araujo PRdoi: 10.1016/j.ajpath.2016.05.020
27441652RNA-binding protein Musashi2 induced by RANKL is critical for osteoclast survival.Cell Death Dis2016 Jul 21Fujiwara Tdoi: 10.1038/cddis.2016.213.
26673327The Msi Family of RNA-Binding Proteins Function Redundantly as Intestinal Oncoproteins.Cell Rep2015 Dec 22Li Ndoi: 10.1016/j.celrep.2015.11.022
26373800The RNA-binding protein Musashi 1 stabilizes the oncotachykinin 1 mRNA in breast cancer cells to promote cell growth.FASEB J2016 JanNahas GRdoi: 10.1096/fj.15-278770
26191146Prognostic value of Musashi-1 in endometrioid adenocarcinoma.Int J Clin Exp Pathol2015 May 1Ma L-
26131972Knockout of RNA Binding Protein MSI2 Impairs Follicle Development in the Mouse Ovary: Characterization of MSI1 and MSI2 during Folliculogenesis.Biomolecules2015 Jun 26Sutherland JMdoi: 10.3390/biom5031228.
26100017RNA-Binding Protein Musashi1 Is a Central Regulator of Adhesion Pathways in Glioblastoma.Mol Cell Biol2015 Sep 1Uren PJdoi: 10.1128/MCB.00410-15
25782991RNA binding protein Musashi-1 directly targets Msi2 and Erh during early testis germ cell development and interacts with IPO5 upon translocation to the nucleus.FASEB J2015 JulSutherland JMdoi: 10.1096/fj.14-265868
28143872Musashi RNA-Binding Proteins as Cancer Drivers and Novel Therapeutic Targets.Clin Cancer Res2017 May 1Kudinov AEdoi: 10.1158/1078-0432.CCR-16-2728
28521458Overexpression of Musashi-1 protein is associated with progression and poor prognosis of gastric cancer.Oncol Lett2017 MayShou Zdoi: 10.3892/ol.2017.5879
28526879Musashi-1 promotes a cancer stem cell lineage and chemoresistance in colorectal cancer cells.Sci Rep2017 May 19Chiou GYdoi: 10.1038/s41598-017-02057-9.
28572454Neurodevelopmental protein Musashi-1 interacts with the Zika genome and promotes viral replication.Science2017 Jul 7Chavali PLdoi: 10.1126/science.aam9243
28714992Musashi 1 regulates the timing and extent of meiotic mRNA translational activation by promoting the use of specific CPEs.Nat Struct Mol Biol2017 AugWeill Ldoi: 10.1038/nsmb.3434
28753936Structural Insight into the Recognition of r(UAG) by Musashi-1 RBD2, and Construction of a Model of Musashi-1 RBD1-2 Bound to the Minimum Target RNA.Molecules2017 Jul 19Iwaoka Rdoi: 10.3390/molecules22071207.
28821879Musashi-1 Enhances Glioblastoma Cell Migration and Cytoskeletal Dynamics through Translational Inhibition of Tensin3.Sci Rep2017 Aug 18Chen HYdoi: 10.1038/s41598-017-09504-7.
29486283Musashi-1 promotes chemoresistant granule formation by PKR/eIF2α signalling cascade in refractory glioblastoma.Biochim Biophys Acta Mol Basis Dis2018 MayChen HYdoi: 10.1016/j.bbadis.2018.02.017
29560998Mechanism of protein-RNA recognition: analysis based on the statistical mechanics of hydration.Phys Chem Chem Phys2018 Apr 4Hayashi Tdoi: 10.1039/C8CP00155C.
30250616Identification of a novel splice variant of the human musashi-1 gene.Oncol Lett2018 OctMa Ldoi: 10.3892/ol.2018.9300
30362859Luteolin inhibits Musashi1 binding to RNA and disrupts cancer phenotypes in glioblastoma cells.RNA Biol2018Yi Cdoi: 10.1080/15476286.2018.1539607
31004009Antagonism between the RNA-binding protein Musashi1 and miR-137 and its potential impact on neurogenesis and glioblastoma development.RNA2019 JulVelasco MXdoi: 10.1261/rna.069211.118
31031868Inhibition of RNA-Binding Protein Musashi-1 Suppresses Malignant Properties and Reverses Paclitaxel Resistance in Ovarian Carcinoma.J Cancer2019 Feb 26Chen Hdoi: 10.7150/jca.27352
31059073Knockdown of MSI1 inhibits the proliferation of human oral squamous cell carcinoma by inactivating STAT3 signaling.Int J Mol Med2019 JulWang CFdoi: 10.3892/ijmm.2019.4181
31061405Musashi binding elements in Zika and related Flavivirus 3'UTRs: A comparative study in silico.Sci Rep2019 May 6Schneider ABdoi: 10.1038/s41598-019-43390-5.
31217428Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia.Nat Commun2019 Jun 19Minuesa Gdoi: 10.1038/s41467-019-10523-3.
Expression
Transcripts
Transcript IDNameLengthRefSeq ID Protein IDLengthRefSeq IDUniportKB ID
ENST00000546622MSI1-202422--- (aa)--
ENST00000257552MSI1-2012975XM_006719403ENSP00000257552362 (aa)XP_006719466O43347
ENST00000546985MSI1-203698-ENSP00000446710233 (aa)-H0YHB7
Gene Model
Click here to download ENSG00000135097's gene model file
Pathways
Pathway IDPathway NameSource
hsa03015mRNA surveillance pathwayKEGG
Phenotypes
ensgIDTraitpValuePubmed ID
ENSG00000135097Atherosclerosis5.3725863E-005-
ENSG00000135097Atherosclerosis5.3118535E-005-
ENSG00000135097Atherosclerosis5.2868065E-005-
Protein-Protein Interaction (PPI)

Clik here to download ENSG00000135097's network

* RBP PPI network refers to all genes directly bind to RBP
Paralogs
Ensembl IDGene SymbolCoverageIdentiy ParalogGene SymbolCoverageIdentiy
ENSG00000135097MSI15245.000ENSG00000197451HNRNPAB7244.000
ENSG00000135097MSI16145.588ENSG00000071626DAZAP15745.588
ENSG00000135097MSI15443.750ENSG00000122566HNRNPA2B16743.750
ENSG00000135097MSI19973.840ENSG00000153944MSI28689.394
ENSG00000135097MSI15246.032ENSG00000152795HNRNPDL9038.554
ENSG00000135097MSI18036.842ENSG00000132819RBM387942.373
ENSG00000135097MSI15241.799ENSG00000139675HNRNPA1L27638.843
ENSG00000135097MSI15339.474ENSG00000136527TRA2B6937.179
ENSG00000135097MSI15042.308ENSG00000135486HNRNPA19942.857
ENSG00000135097MSI15247.619ENSG00000138668HNRNPD10052.174
ENSG00000135097MSI15041.758ENSG00000170144HNRNPA37038.258
Orthologs
Ensembl IDGene SymbolCoverageIdentiy OrthologGene SymbolCoverageIdentiy Species
ENSG00000135097MSI19987.069ENSAPOG00000003191MSI110083.791Acanthochromis_polyacanthus
ENSG00000135097MSI110084.254ENSAPOG00000023458-10084.254Acanthochromis_polyacanthus
ENSG00000135097MSI19981.690ENSAMEG00000013302MSI110081.365Ailuropoda_melanoleuca
ENSG00000135097MSI19987.931ENSACIG00000017754-7882.675Amphilophus_citrinellus
ENSG00000135097MSI110083.791ENSAOCG00000003804MSI110083.791Amphiprion_ocellaris
ENSG00000135097MSI19980.172ENSAOCG00000009031-9577.778Amphiprion_ocellaris
ENSG00000135097MSI110083.791ENSAPEG00000003245MSI110083.791Amphiprion_percula
ENSG00000135097MSI110084.254ENSAPEG00000006857-8484.254Amphiprion_percula
ENSG00000135097MSI19987.500ENSATEG00000017059MSI110080.435Anabas_testudineus
ENSG00000135097MSI19979.762ENSATEG00000023779-10078.415Anabas_testudineus
ENSG00000135097MSI110096.419ENSACAG00000002762MSI110096.419Anolis_carolinensis
ENSG00000135097MSI19089.520ENSANAG00000027901-9296.309Aotus_nancymaae
ENSG00000135097MSI1100100.000ENSANAG00000027151MSI1100100.000Aotus_nancymaae
ENSG00000135097MSI110083.242ENSACLG00000011230MSI110083.242Astatotilapia_calliptera
ENSG00000135097MSI110083.978ENSACLG00000000117-10085.337Astatotilapia_calliptera
ENSG00000135097MSI19985.776ENSAMXG00000038960msi17683.735Astyanax_mexicanus
ENSG00000135097MSI1100100.000ENSBTAG00000009800MSI1100100.000Bos_taurus
ENSG00000135097MSI1100100.000ENSCJAG00000008578MSI1100100.000Callithrix_jacchus
ENSG00000135097MSI110099.724ENSCAFG00000010283MSI110099.724Canis_familiaris
ENSG00000135097MSI194100.000ENSCAFG00020020585MSI1100100.000Canis_lupus_dingo
ENSG00000135097MSI110094.580ENSCHIG00000024304MSI110094.580Capra_hircus
ENSG00000135097MSI194100.000ENSTSYG00000033949MSI195100.000Carlito_syrichta
ENSG00000135097MSI19489.776ENSCAPG00000003919MSI18989.776Cavia_aperea
ENSG00000135097MSI198100.000ENSCPOG00000012361MSI1100100.000Cavia_porcellus
ENSG00000135097MSI1100100.000ENSCCAG00000035567MSI1100100.000Cebus_capucinus
ENSG00000135097MSI1100100.000ENSCATG00000030019MSI1100100.000Cercocebus_atys
ENSG00000135097MSI198100.000ENSCLAG00000011329MSI1100100.000Chinchilla_lanigera
ENSG00000135097MSI175100.000ENSCSAG00000002265MSI19696.390Chlorocebus_sabaeus
ENSG00000135097MSI110095.856ENSCPBG00000011349MSI110095.856Chrysemys_picta_bellii
ENSG00000135097MSI198100.000ENSCANG00000040651MSI1100100.000Colobus_angolensis_palliatus
ENSG00000135097MSI1100100.000ENSCGRG00001018883Msi1100100.000Cricetulus_griseus_chok1gshd
ENSG00000135097MSI194100.000ENSCGRG00000002191Msi172100.000Cricetulus_griseus_crigri
ENSG00000135097MSI110083.516ENSCSEG00000005834-10083.516Cynoglossus_semilaevis
ENSG00000135097MSI19982.328ENSCSEG00000011032MSI110078.299Cynoglossus_semilaevis
ENSG00000135097MSI19985.776ENSCSEG00000008352-10083.149Cynoglossus_semilaevis
ENSG00000135097MSI16468.398ENSCVAG00000017463-8968.398Cyprinodon_variegatus
ENSG00000135097MSI19987.500ENSCVAG00000009100MSI110084.254Cyprinodon_variegatus
ENSG00000135097MSI18082.096ENSDARG00000102015CABZ01037298.18982.096Danio_rerio
ENSG00000135097MSI19987.500ENSDARG00000010710msi110085.022Danio_rerio
ENSG00000135097MSI19889.970ENSDNOG00000005713MSI19189.970Dasypus_novemcinctus
ENSG00000135097MSI19899.102ENSDORG00000005610Msi19995.480Dipodomys_ordii
ENSG00000135097MSI19895.732ENSETEG00000004756MSI110095.732Echinops_telfairi
ENSG00000135097MSI1100100.000ENSEASG00005004736MSI1100100.000Equus_asinus_asinus
ENSG00000135097MSI1100100.000ENSECAG00000017526MSI1100100.000Equus_caballus
ENSG00000135097MSI19980.408ENSELUG00000023280-10080.938Esox_lucius
ENSG00000135097MSI19980.478ENSELUG00000023219MSI19280.387Esox_lucius
ENSG00000135097MSI1100100.000ENSFCAG00000011007MSI1100100.000Felis_catus
ENSG00000135097MSI19895.820ENSFALG00000007574MSI110095.820Ficedula_albicollis
ENSG00000135097MSI19899.695ENSFDAG00000019586MSI110099.695Fukomys_damarensis
ENSG00000135097MSI110084.530ENSFHEG00000022446MSI110084.530Fundulus_heteroclitus
ENSG00000135097MSI19987.069ENSFHEG00000003560-10083.791Fundulus_heteroclitus
ENSG00000135097MSI110076.584ENSGMOG00000017838-10076.584Gadus_morhua
ENSG00000135097MSI110082.597ENSGMOG00000001006MSI19982.320Gadus_morhua
ENSG00000135097MSI19495.238ENSGALG00000007227MSI19886.957Gallus_gallus
ENSG00000135097MSI19969.099ENSGAFG00000005860-10065.205Gambusia_affinis
ENSG00000135097MSI19885.380ENSGAFG00000021522MSI19485.380Gambusia_affinis
ENSG00000135097MSI19984.914ENSGACG00000012679MSI110083.425Gasterosteus_aculeatus
ENSG00000135097MSI110080.663ENSGACG00000008674-10080.663Gasterosteus_aculeatus
ENSG00000135097MSI110095.580ENSGAGG00000016037MSI110095.580Gopherus_agassizii
ENSG00000135097MSI194100.000ENSGGOG00000010328MSI1100100.000Gorilla_gorilla
ENSG00000135097MSI110083.242ENSHBUG00000021921MSI110083.242Haplochromis_burtoni
ENSG00000135097MSI110083.978ENSHBUG00000011841-10083.978Haplochromis_burtoni
ENSG00000135097MSI110099.724ENSHGLG00000012782MSI110099.724Heterocephalus_glaber_female
ENSG00000135097MSI19899.695ENSHGLG00100016848MSI110099.695Heterocephalus_glaber_male
ENSG00000135097MSI19987.069ENSHCOG00000012067-10078.689Hippocampus_comes
ENSG00000135097MSI19984.914ENSHCOG00000012019MSI110080.938Hippocampus_comes
ENSG00000135097MSI19984.914ENSIPUG00000001976msi110082.320Ictalurus_punctatus
ENSG00000135097MSI194100.000ENSSTOG00000009799MSI1100100.000Ictidomys_tridecemlineatus
ENSG00000135097MSI19891.228ENSJJAG00000010643-10084.254Jaculus_jaculus
ENSG00000135097MSI1100100.000ENSJJAG00000010463Msi1100100.000Jaculus_jaculus
ENSG00000135097MSI19987.069ENSKMAG00000019877-10083.578Kryptolebias_marmoratus
ENSG00000135097MSI110083.702ENSKMAG00000011251MSI110083.702Kryptolebias_marmoratus
ENSG00000135097MSI19987.500ENSLBEG00000008789MSI110084.254Labrus_bergylta
ENSG00000135097MSI19986.207ENSLBEG00000001375-10083.242Labrus_bergylta
ENSG00000135097MSI19887.427ENSLACG00000018287MSI110087.427Latimeria_chalumnae
ENSG00000135097MSI15070.000ENSLOCG00000008618zgc:1107967170.000Lepisosteus_oculatus
ENSG00000135097MSI19189.426ENSLAFG00000009412MSI110089.426Loxodonta_africana
ENSG00000135097MSI198100.000ENSMFAG00000001798MSI1100100.000Macaca_fascicularis
ENSG00000135097MSI19798.291ENSMMUG00000031527MSI19798.291Macaca_mulatta
ENSG00000135097MSI1100100.000ENSMNEG00000040034MSI1100100.000Macaca_nemestrina
ENSG00000135097MSI198100.000ENSMLEG00000003921MSI1100100.000Mandrillus_leucophaeus
ENSG00000135097MSI110083.425ENSMAMG00000002279MSI110083.425Mastacembelus_armatus
ENSG00000135097MSI19986.207ENSMAMG00000018426-10083.791Mastacembelus_armatus
ENSG00000135097MSI110083.242ENSMZEG00005026892MSI110083.242Maylandia_zebra
ENSG00000135097MSI19987.069ENSMZEG00005000340-10083.978Maylandia_zebra
ENSG00000135097MSI17398.817ENSMGAG00000016518-10098.817Meleagris_gallopavo
ENSG00000135097MSI175100.000ENSMAUG00000016820Msi1100100.000Mesocricetus_auratus
ENSG00000135097MSI1100100.000ENSMICG00000033181MSI1100100.000Microcebus_murinus
ENSG00000135097MSI110099.724ENSMOCG00000002286Msi110099.724Microtus_ochrogaster
ENSG00000135097MSI19986.207ENSMMOG00000012265-9980.415Mola_mola
ENSG00000135097MSI19978.879ENSMMOG00000010492MSI19476.316Mola_mola
ENSG00000135097MSI19167.771ENSMODG00000003189-10067.771Monodelphis_domestica
ENSG00000135097MSI19985.345ENSMALG00000001426-10085.044Monopterus_albus
ENSG00000135097MSI110083.978ENSMALG00000017889MSI110083.978Monopterus_albus
ENSG00000135097MSI110099.448MGP_CAROLIEiJ_G0027626Msi110099.490Mus_caroli
ENSG00000135097MSI110099.448ENSMUSG00000054256Msi110099.490Mus_musculus
ENSG00000135097MSI110099.171MGP_PahariEiJ_G0024206Msi110099.171Mus_pahari
ENSG00000135097MSI110099.448MGP_SPRETEiJ_G0028624Msi110099.490Mus_spretus
ENSG00000135097MSI194100.000ENSMPUG00000003168MSI1100100.000Mustela_putorius_furo
ENSG00000135097MSI19490.179ENSMLUG00000010313MSI110090.179Myotis_lucifugus
ENSG00000135097MSI19893.855ENSNGAG00000014508Msi19793.855Nannospalax_galili
ENSG00000135097MSI18877.432ENSNBRG00000018012MSI19977.432Neolamprologus_brichardi
ENSG00000135097MSI19987.069ENSNBRG00000000841-10083.978Neolamprologus_brichardi
ENSG00000135097MSI19189.634ENSNLEG00000015636MSI110089.634Nomascus_leucogenys
ENSG00000135097MSI19477.744ENSMEUG00000015759MSI110077.744Notamacropus_eugenii
ENSG00000135097MSI19492.063ENSOPRG00000016879MSI110092.063Ochotona_princeps
ENSG00000135097MSI198100.000ENSODEG00000006328MSI1100100.000Octodon_degus
ENSG00000135097MSI110083.516ENSONIG00000019452-10083.516Oreochromis_niloticus
ENSG00000135097MSI110083.978ENSONIG00000011182MSI110083.978Oreochromis_niloticus
ENSG00000135097MSI19499.678ENSOCUG00000027716MSI110099.678Oryctolagus_cuniculus
ENSG00000135097MSI19987.931ENSORLG00000019978-10084.530Oryzias_latipes
ENSG00000135097MSI110083.791ENSORLG00000029593MSI110083.791Oryzias_latipes
ENSG00000135097MSI110084.530ENSORLG00020001208-7184.530Oryzias_latipes_hni
ENSG00000135097MSI19986.207ENSORLG00020008266MSI19983.041Oryzias_latipes_hni
ENSG00000135097MSI19986.207ENSORLG00015003916MSI110083.791Oryzias_latipes_hsok
ENSG00000135097MSI19987.931ENSORLG00015013672-7681.215Oryzias_latipes_hsok
ENSG00000135097MSI110084.807ENSOMEG00000017536MSI110084.807Oryzias_melastigma
ENSG00000135097MSI19886.842ENSOMEG00000002272-10084.615Oryzias_melastigma
ENSG00000135097MSI19995.604ENSOGAG00000003847MSI19995.604Otolemur_garnettii
ENSG00000135097MSI19496.061ENSOARG00000012097MSI110096.061Ovis_aries
ENSG00000135097MSI198100.000ENSPPAG00000043073MSI1100100.000Pan_paniscus
ENSG00000135097MSI1100100.000ENSPPRG00000000370MSI1100100.000Panthera_pardus
ENSG00000135097MSI194100.000ENSPTIG00000008913MSI1100100.000Panthera_tigris_altaica
ENSG00000135097MSI1100100.000ENSPTRG00000005531MSI1100100.000Pan_troglodytes
ENSG00000135097MSI110099.724ENSPANG00000006335MSI110099.724Papio_anubis
ENSG00000135097MSI19988.362ENSPKIG00000016497MSI110085.083Paramormyrops_kingsleyae
ENSG00000135097MSI19685.879ENSPKIG00000023575-10083.978Paramormyrops_kingsleyae
ENSG00000135097MSI19892.105ENSPSIG00000011608-9392.105Pelodiscus_sinensis
ENSG00000135097MSI18092.576ENSPSIG00000009621-10092.576Pelodiscus_sinensis
ENSG00000135097MSI15293.939ENSPSIG00000016295-9393.939Pelodiscus_sinensis
ENSG00000135097MSI19987.931ENSPMGG00000000514MSI19781.763Periophthalmus_magnuspinnatus
ENSG00000135097MSI19970.588ENSPMGG00000007743-8971.014Periophthalmus_magnuspinnatus
ENSG00000135097MSI19994.958ENSPEMG00000010491Msi19994.958Peromyscus_maniculatus_bairdii
ENSG00000135097MSI110083.791ENSPFOG00000008319-8683.791Poecilia_formosa
ENSG00000135097MSI19993.714ENSPFOG00000013113MSI110084.254Poecilia_formosa
ENSG00000135097MSI110083.791ENSPLAG00000012431-9783.791Poecilia_latipinna
ENSG00000135097MSI110084.254ENSPLAG00000014025-10084.254Poecilia_latipinna
ENSG00000135097MSI19987.931ENSPMEG00000012796MSI110084.254Poecilia_mexicana
ENSG00000135097MSI110083.242ENSPMEG00000007025-9378.070Poecilia_mexicana
ENSG00000135097MSI19987.069ENSPREG00000021416-9878.249Poecilia_reticulata
ENSG00000135097MSI17085.890ENSPREG00000014574-10078.571Poecilia_reticulata
ENSG00000135097MSI110099.171ENSPPYG00000005027MSI110099.171Pongo_abelii
ENSG00000135097MSI19876.923ENSPCAG00000002300MSI110076.923Procavia_capensis
ENSG00000135097MSI1100100.000ENSPCOG00000017341MSI1100100.000Propithecus_coquereli
ENSG00000135097MSI19882.927ENSPVAG00000002225MSI110082.927Pteropus_vampyrus
ENSG00000135097MSI110083.242ENSPNYG00000004379MSI110083.242Pundamilia_nyererei
ENSG00000135097MSI110083.978ENSPNYG00000002529-10083.978Pundamilia_nyererei
ENSG00000135097MSI19985.345ENSPNAG00000019337msi110082.597Pygocentrus_nattereri
ENSG00000135097MSI19499.678ENSRNOG00000001156Msi110099.678Rattus_norvegicus
ENSG00000135097MSI194100.000ENSRBIG00000036889MSI1100100.000Rhinopithecus_bieti
ENSG00000135097MSI19499.697ENSRROG00000041076MSI19399.697Rhinopithecus_roxellana
ENSG00000135097MSI198100.000ENSSBOG00000030259MSI198100.000Saimiri_boliviensis_boliviensis
ENSG00000135097MSI19487.255ENSSHAG00000006834MSI110087.255Sarcophilus_harrisii
ENSG00000135097MSI19987.069ENSSFOG00015005350MSI19688.012Scleropages_formosus
ENSG00000135097MSI19886.842ENSSFOG00015014964-9586.842Scleropages_formosus
ENSG00000135097MSI19485.818ENSSMAG00000009156-7185.818Scophthalmus_maximus
ENSG00000135097MSI19987.931ENSSMAG00000018824MSI19781.763Scophthalmus_maximus
ENSG00000135097MSI19985.776ENSSDUG00000022697-10083.516Seriola_dumerili
ENSG00000135097MSI110084.254ENSSDUG00000001027MSI110084.254Seriola_dumerili
ENSG00000135097MSI19987.500ENSSLDG00000016832MSI110084.254Seriola_lalandi_dorsalis
ENSG00000135097MSI19985.776ENSSLDG00000018706-9782.229Seriola_lalandi_dorsalis
ENSG00000135097MSI110095.028ENSSPUG00000015741MSI110095.028Sphenodon_punctatus
ENSG00000135097MSI17072.393ENSSPAG00000014085-10068.750Stegastes_partitus
ENSG00000135097MSI15295.062ENSSPAG00000015573zgc:1107968274.375Stegastes_partitus
ENSG00000135097MSI19987.500ENSSPAG00000013098-10086.217Stegastes_partitus
ENSG00000135097MSI110099.724ENSSSCG00000029365MSI110099.724Sus_scrofa
ENSG00000135097MSI19896.784ENSTGUG00000009534MSI110096.784Taeniopygia_guttata
ENSG00000135097MSI18180.952ENSTRUG00000016249MSI110073.783Takifugu_rubripes
ENSG00000135097MSI19978.448ENSTRUG00000015636-7975.988Takifugu_rubripes
ENSG00000135097MSI110079.178ENSTNIG00000011469MSI110079.178Tetraodon_nigroviridis
ENSG00000135097MSI19862.432ENSTNIG00000019814-9962.432Tetraodon_nigroviridis
ENSG00000135097MSI19489.377ENSTBEG00000007182MSI110089.377Tupaia_belangeri
ENSG00000135097MSI19881.287ENSTTRG00000005663MSI110081.287Tursiops_truncatus
ENSG00000135097MSI175100.000ENSUAMG00000015514MSI19492.694Ursus_americanus
ENSG00000135097MSI19995.868ENSUMAG00000006176MSI19092.405Ursus_maritimus
ENSG00000135097MSI19899.099ENSVVUG00000020993MSI110099.099Vulpes_vulpes
ENSG00000135097MSI110091.209ENSXETG00000012216msi110091.257Xenopus_tropicalis
ENSG00000135097MSI19970.259ENSXCOG00000017605MSI18971.930Xiphophorus_couchianus
ENSG00000135097MSI110084.254ENSXMAG00000027103MSI110073.984Xiphophorus_maculatus
ENSG00000135097MSI19986.207ENSXMAG00000018237-10083.516Xiphophorus_maculatus
Gene Ontology
Go IDGo_termPubmedIDEvidenceCategory
GO:0003723RNA binding22681889.HDAFunction
GO:0003723RNA binding21873635.IBAFunction
GO:0005634nucleus21873635.IBAComponent
GO:0005634nucleus-IEAComponent
GO:0005737cytoplasm21873635.IBAComponent
GO:0005844polysome21873635.IBAComponent
GO:0007399nervous system development9790759.TASProcess
GO:0008266poly(U) RNA binding-IEAFunction
GO:0042802identical protein binding-IEAFunction
GO:1990904ribonucleoprotein complex21873635.IBAComponent
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