EuRBPDB

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TCGA tumor abbreviations
  • ACCAdrenocortical carcinoma
  • BLCABladder Urothelial Carcinoma
  • BRCABreast invasive carcinoma
  • CESCCervical squamous cell carcinoma and endocervical adenocarcinoma
  • CHOLCholangio carcinoma
  • COADColon adenocarcinoma
  • DLBCLymphoid Neoplasm Diffuse Large B-cell Lymphoma
  • ESCAEsophageal carcinoma
  • GBMGlioblastoma multiforme
  • HNSCHead and Neck squamous cell carcinoma
  • KICHKidney Chromophobe
  • KIRCKidney renal clear cell carcinoma
  • KIRPKidney renal papillary cell carcinoma
  • LAMLAcute Myeloid Leukemia
  • LGGBrain Lower Grade Glioma
  • LIHCLiver hepatocellular carcinoma
  • LUADLung adenocarcinoma
  • LUSCLung squamous cell carcinoma
  • MESOMesothelioma
  • OVOvarian serous cystadenocarcinoma
  • PAADPancreatic adenocarcinoma
  • PCPGPheochromocytoma and Paraganglioma
  • PRADProstate adenocarcinoma
  • READRectum adenocarcinoma
  • SARCSarcoma
  • SKCMSkin Cutaneous Melanoma
  • STADStomach adenocarcinoma
  • TGCTThyroid carcinoma
  • THCAThyroid carcinoma
  • THYMThymoma
  • UCECUterine Corpus Endometrial Carcinoma
  • UCSUterine Carcinosarcoma
  • UVMUveal Melanoma

Note: Click here to get the extension of tumor abbreviations.


  • Cancer Related Information
  • Basic Information

Cancer associated literatures
PIDTitleArticle TimeAuthorDoi
20856207The RNA-binding protein La contributes to cell proliferation and CCND1 expression.Oncogene2011 Jan 27Sommer Gdoi: 10.1038/onc.2010.425
22016766Implication of RNA-binding protein La in proliferation, migration and invasion of lymph node-metastasized hypopharyngeal SCC cells.PLoS One2011Sommer Gdoi: 10.1371/journal.pone.0025402
27105491The La protein counteracts cisplatin-induced cell death by stimulating protein synthesis of anti-apoptotic factor Bcl2.Oncotarget2016 May 17Heise Tdoi: 10.18632/oncotarget.8819.

Expression in 33 cancers

Mutations
CancerChrPosition Mutation TypedbSNPProtein-change Allele FreqRBD
ACCchr2169811282In_Frame_DelnovelS366_D367delinsN0.44
BLCAchr2169808544Missense_MutationnovelR206T0.26
BLCAchr2169810295Nonsense_MutationnovelE228*0.32
BLCAchr2169808867Missense_MutationnovelE212K0.24
BLCAchr2169810317Missense_MutationNAK235T0.23
BRCAchr2169810972Missense_MutationnovelE309K0.05
BRCAchr2169808871Missense_MutationnovelA213E0.14
BRCAchr2169807039SilentNAK174K0.34
BRCAchr2169810282Splice_SiteNAX224_splice0.13
CESCchr2169810282Splice_SiteNAX224_splice0.42
COADchr21698118753'UTRnovel0.27
COADchr21698118713'UTRrs7708084390.39
COADchr2169810400Missense_MutationNAD263Y0.13
COADchr2169805784Missense_MutationNAL97P0.09
GBMchr2169800979Missense_MutationnovelN7Y0.08
HNSCchr2169811025Silentrs779625970L326L0.34
KIRCchr2169805531Frame_Shift_InsnovelD43Kfs*110.04RRM_1
KIRCchr2169805533Nonsense_MutationnovelD43Sfs*70.04RRM_1
KIRPchr2169810985Missense_Mutationrs777853278E313A0.31
LGGchr2169810867SilentNAL274L0.32
LGGchr2169808506Missense_MutationNAN193K0.17
LIHCchr21698118153'UTRnovel0.23
LUADchr2169808539Missense_MutationnovelK204N0.39
LUADchr2169800980Missense_MutationNAN7I0.28
LUSCchr2169810334Missense_MutationnovelD241H0.15
PRADchr2169805527In_Frame_InsnovelK41_L42dup0.59RRM_1
PRADchr2169811021Frame_Shift_DelnovelL326*0.74
READchr2169811224Missense_MutationnovelQ347K0.21
READchr2169806891Missense_MutationnovelK151T0.16
SKCMchr2169805503SilentNAR32R0.27
SKCMchr2169801027Splice_SitenovelX22_splice0.15
STADchr2169808498Frame_Shift_Delrs753297385N193Mfs*130.36
STADchr2169801008Missense_MutationnovelK16N0.08
STADchr2169808498Frame_Shift_Delrs753297385N193Mfs*130.44
STADchr21698118763'UTRrs7593365700.31
UCECchr2169805502Missense_MutationNAR32Q0.24RRM_1
UCECchr2169808500Missense_MutationNAK191N0.32
UCECchr2169811271Silentrs555917812T362T0.35
UCECchr21698118173'UTRnovel0.54
UCECchr2169805673Missense_MutationNAR60H0.42RRM_1
UCECchr21698120443'UTRnovel0.4
UCECchr2169806894Splice_SiteNAX151_splice0.09
UCECchr2169806788Missense_MutationnovelG117C0.38
UCECchr2169811271Silentrs555917812T362T0.43
UCECchr2169807017Missense_MutationnovelF167C0.23
UCECchr2169805775Missense_MutationnovelS94N0.09
UCECchr21698118753'UTRnovel0.35
UCECchr21698118003'UTRnovel0.47
UCECchr2169808534Missense_MutationnovelA203T0.21
UCECchr21698009585'UTRrs3739686660.22
UCECchr2169810421Missense_MutationnovelE270K0.29
UCECchr2169806869Missense_MutationnovelR144G0.17
UCECchr2169808514Missense_MutationnovelR196I0.34
UCECchr21698119563'UTRnovel0.43
UCECchr21698118743'UTRnovel0.07
UCECchr2169806876Missense_MutationnovelL146S0.3
UCECchr2169806829Nonsense_MutationnovelW130*0.38
UCECchr2169805514Missense_MutationNAL36P0.22RRM_1
UCECchr2169807046Nonsense_MutationNAE177*0.4
UCECchr2169805841Splice_SitenovelX115_splice0.4
UCECchr21698120433'UTRrs5673496320.35
UCECchr2169808498Frame_Shift_Delrs753297385N193Mfs*130.54

Copy Number Variations (CNVs)
CancerTypeFreq Q-value
PAADAMP0.06520.1091
PAADDEL0.03260.2014

Survival Analysis
CancerP-value Q-value
KIRC0.034

Kaplan-Meier Survival Analysis

ACC0.0019

Kaplan-Meier Survival Analysis

HNSC0.00026

Kaplan-Meier Survival Analysis

SKCM0.00071

Kaplan-Meier Survival Analysis

KIRP0.00011

Kaplan-Meier Survival Analysis

PAAD0.0052

Kaplan-Meier Survival Analysis

KICH0.031

Kaplan-Meier Survival Analysis

UCEC0.0055

Kaplan-Meier Survival Analysis

LIHC0.0001

Kaplan-Meier Survival Analysis

LGG0.015

Kaplan-Meier Survival Analysis

THCA0.031

Kaplan-Meier Survival Analysis

LUAD0.0068

Kaplan-Meier Survival Analysis

OV0.02

Kaplan-Meier Survival Analysis

Drugs

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Eesembl ID



Cell lines and drugs in GSE70138 or GSE92742

  • Description
  • RBDs
  • RBPome
  • PRI
  • Literatures
  • Expression
  • Transcripts
  • Gene Model
  • Pathways
  • PPI
  • Paralogs
  • Orthologs
  • Gene Ontology
Description
Ensembl ID
ENSG00000138385 (Gene tree)
Gene ID
6741
Gene Symbol
SSB
Alias
LARP3|La|La/SSB
Full Name
small RNA binding exonuclease protection factor La
Gene Type
protein_coding
Species
Homo_sapiens
Status
confidence
Strand
Plus strand
Length
20,132 bases
Position
chr2:169,791,933-169,812,064
Accession
11316
RBP type
canonical RBP
Summary
The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein. [provided by RefSeq, Jun 2014]
RNA binding domains(RBDs)
Protein IDDomain Pfam IDE-value Domain number Total number
ENSP00000260956RRM_1PF00076.222.4e-1511
ENSP00000386636RRM_1PF00076.222.4e-1511
ENSP00000397029RRM_1PF00076.228.1e-1211
ENSP00000396890RRM_1PF00076.224.1e-1111
ENSP00000260956RRM_3PF08777.115.7e-3111
ENSP00000386636RRM_3PF08777.115.7e-3111
ENSP00000397029LaPF05383.178.1e-2211
ENSP00000260956LaPF05383.171.3e-2111
ENSP00000386636LaPF05383.171.3e-2111
RNA binding proteome (RBPome)
PIDTitleMethod TimeAuthorDoi
22681889The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts4SURIC & HEK2932012 MayBaltz AGDOI: 10.1016/j.molcel.2012.05.021
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & HEK2932019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & HEK2932018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
29431736Capturing the interactome of newly transcribed RNANascentRICK & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
29431736Capturing the interactome of newly transcribed RNAPolyT-RICK & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
29431736Capturing the interactome of newly transcribed RNARIC & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
29431736Capturing the interactome of newly transcribed RNARICK & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
22658674Insights into RNA biology from an atlas of mammalian mRNA-binding proteinsRIC & Hela2012 May 31Castello ADOI: 10.1016/j.cell.2012.04.031
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & Hela2018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & MCF10A2019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & MCF72018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & U2OS2019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
27453046Comprehensive Identification of RNA-Binding Domains in Human CellsRIC & Hela2016 Aug 18Castello ADOI: 10.1016/j.molcel.2016.06.029
30352994Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome captureRIC & Jurkat2018 Oct 23Perez-Perri JIDOI:10.1038/s41467-018-06557-8
Protein-RNA interaction(RNA-Binding Site)
Click here to download all RNA binding sites
Click here to download all RNA binding sites

Literatures on RNA binding capacity
PIDTitleArticle TimeAuthorDoi
7933082La autoantigen alleviates translational repression by the 5' leader sequence of the human immunodeficiency virus type 1 mRNA.J Virol1994 NovSvitkin YV-
2468131Ribonucleoprotein SS-B/La belongs to a protein family with consensus sequences for RNA-binding.Nucleic Acids Res1989 Mar 25Chan EK-
2436670Multiple phosphorylation of human SS-B/LA autoantigen and its effect on poly(U) and autoantibody binding.Biochim Biophys Acta1987 Apr 22Pfeifle J-
8683593A Xenopus laevis homologue of the La autoantigen binds the pyrimidine tract of the 5' UTR of ribosomal protein mRNAs in vitro: implication of a protein factor in complex formation.J Mol Biol1996 Jun 28Pellizzoni L-
11080168Euplotes telomerase contains an La motif protein produced by apparent translational frameshifting.EMBO J2000 Nov 15Aigner S-
27345152The Lupus Autoantigen La Prevents Mis-channeling of tRNA Fragments into the Human MicroRNA Pathway.Mol Cell2016 Jul 7Hasler Ddoi: 10.1016/j.molcel.2016.05.026
7556214Anti-La monoclonal antibodies recognizing epitopes within the RNA-binding domain of the La protein show differential capacities to immunoprecipitate RNA-associated La protein.Eur J Biochem1995 Sep 1Pruijn GJ-
6232502Association of an RNA polymerase III transcription factor with a ribonucleoprotein complex recognized by autoimmune sera.Nucleic Acids Res1984 Apr 11Gottesfeld JM-
8972196The La autoantigen contains a dimerization domain that is essential for enhancing translation.Mol Cell Biol1997 JanCraig AW-
8035794Developmental characterization of a Drosophila RNA-binding protein homologous to the human systemic lupus erythematosus-associated La/SS-B autoantigen.Mol Cell Biol1994 AugBai C-
11435567Characterization of nuclear RNases that cleave hepatitis B virus RNA near the La protein binding site.J Virol2001 AugHeise T-
15371415The La motif and the RNA recognition motifs of human La autoantigen contribute individually to RNA recognition and subcellular localization.J Biol Chem2004 Nov 26Horke S-
22363785Two major autoantibody clusters in systemic lupus erythematosus.PLoS One2012Ching KHdoi: 10.1371/journal.pone.0032001
2438757Epitopes and structural domains of a RNA-binding nuclear protein, SS-B/La: similarities with adenovirus DNA-binding protein.Scand J Rheumatol Suppl1986Chan EK-
9003790General RNA binding proteins render translation cap dependent.EMBO J1996 Dec 16Svitkin YV-
8454877Characterization of the mouse autoantigen La (SS-B). Identification of conserved RNA-binding motifs, a putative ATP binding site and reactivity of recombinant protein with poly(U) and human autoantibodies.J Immunol1993 Apr 1Topfer F-
23129761Sjogren syndrome antigen B (SSB)/La promotes global microRNA expression by binding microRNA precursors through stem-loop recognition.J Biol Chem2013 Jan 4Liang Cdoi: 10.1074/jbc.M112.401323
22207702La autoantigen mediates oxidant induced de novo Nrf2 protein translation.Mol Cell Proteomics2012 JunZhang Jdoi: 10.1074/mcp.M111.015032
7518914The La antigen inhibits the activation of the interferon-inducible protein kinase PKR by sequestering and unwinding double-stranded RNA.Nucleic Acids Res1994 Jul 11Xiao Q-
9971802Intracellular redistribution of truncated La protein produced by poliovirus 3Cpro-mediated cleavage.J Virol1999 MarShiroki K-
2476998Sjgren's syndrome nuclear antigen B (La): cDNA cloning, structural domains, and autoepitopes.J Autoimmun1989 AugChan EK-
9778034Identification of human autoantigen La/SS-B as BC1/BC200 RNA-binding protein.DNA Cell Biol1998 SepKremerskothen J-
2445893Human autoantibody-reactive epitopes of SS-B/La are highly conserved in comparison with epitopes recognized by murine monoclonal antibodies.J Exp Med1987 Dec 1Chan EK-
9237100Phage-displayed La/SS-B antigen as a diagnostic reagent.Immunotechnology1997 JunPoon VK-
8627683Sequences within a small yeast RNA required for inhibition of internal initiation of translation: interaction with La and other cellular proteins influences its inhibitory activity.J Virol1996 MarDas S-
7799435A yeast RNA binding protein that resembles the human autoantigen La.J Mol Biol1995 Jan 13Lin-Marq N-
12083808Identification and cloning of a new protein that binds the 3(') untranslated region of alpha-striated tropomyosin.Mol Genet Metab2002 JunFang HL-
15016896A peptide from autoantigen La blocks poliovirus and hepatitis C virus cap-independent translation and reveals a single tyrosine critical for La RNA binding and translation stimulation.J Virol2004 AprIzumi RE-
17363515From mRNA metabolism to cancer therapy: chronic myelogenous leukemia shows the way.Clin Cancer Res2007 Mar 15Perrotti D-
17346312Specific interaction of HeLa cell proteins with coxsackievirus B3 3'UTR: La autoantigen binds the 3' and 5'UTR independently of the poly(A) tail.Cell Microbiol2007 JulCheung P-
22208657Primary Sjgren's syndrome and the type I interferon system.Curr Pharm Biotechnol2012 AugNordmark G-
29109527The RNA binding protein La/SS-B promotes RIG-I-mediated type I and type III IFN responses following Sendai viral infection.Sci Rep2017 Nov 6Mahony Rdoi: 10.1038/s41598-017-15197-9.
19299548A comprehensive analysis of the La-motif protein superfamily.RNA2009 MayBousquet-Antonelli Cdoi: 10.1261/rna.1478709
17888216Ribosomal P protein P0 as a candidate for the target antigen of anti-endothelial cell antibodies in mixed connective tissue disease.Clin Exp Rheumatol2007 Jul-AugNaniwa T-
2411763Immunologic and structural studies of the lupus/Sjgren's syndrome autoantigen, La/SSB, with a monoclonal antibody.J Clin Invest1985 AugHarley JB-
9601606New nuclear functions for calmodulin.Cell Calcium1998 Feb-MarAgell N-
9409781La autoantigen binding to a 5' cis-element of rubella virus RNA correlates with element function in vivo.Gene1997 Nov 12Duncan RC-
8709254Autoantigens interact with cis-acting elements of rubella virus RNA.J Virol1996 SepPogue GP-
11342556Contributions of the individual domains in human La protein to its RNA 3'-end binding activity.J Biol Chem2001 Jul 20Ohndorf UM-
11125164Binding of the La autoantigen to the hepatitis C virus 3' untranslated region protects the RNA from rapid degradation in vitro.J Gen Virol2001 JanSpangberg K-
27436793Hydrogen peroxide induces La cytoplasmic shuttling and increases hepatitis C virus internal ribosome entry site-dependent translation.J Gen Virol2016 SepChan SWdoi: 10.1099/jgv.0.000556
Expression
Transcripts
Transcript IDNameLengthRefSeq ID Protein IDLengthRefSeq IDUniportKB ID
ENST00000474273SSB-210735--- (aa)--
ENST00000490914SSB-211754--- (aa)--
ENST00000470621SSB-209440--- (aa)--
ENST00000494051SSB-212392--- (aa)--
ENST00000409333SSB-2021782-ENSP00000386636408 (aa)-P05455
ENST00000417292SSB-204545-ENSP00000396890120 (aa)-E9PGX9
ENST00000422006SSB-2052463-ENSP00000397029184 (aa)-E7ERC4
ENST00000468600SSB-208290--- (aa)--
ENST00000461708SSB-206619--- (aa)--
ENST00000260956SSB-2011709-ENSP00000260956408 (aa)-P05455
ENST00000413002SSB-203674-ENSP00000395758134 (aa)-E9PFL9
ENST00000465871SSB-207421--- (aa)--
Gene Model
Click here to download ENSG00000138385's gene model file
Pathways
Pathway IDPathway NameSource
hsa05322Systemic lupus erythematosusKEGG
Protein-Protein Interaction (PPI)

Clik here to download ENSG00000138385's network

* RBP PPI network refers to all genes directly bind to RBP
Paralogs
Ensembl IDGene SymbolCoverageIdentiy ParalogGene SymbolCoverageIdentiy
ENSG00000138385SSB9831.092ENSG00000174720LARP77339.216
Orthologs
Ensembl IDGene SymbolCoverageIdentiy OrthologGene SymbolCoverageIdentiy Species
ENSG00000138385SSB9863.559ENSAPOG00000003448ssb10054.768Acanthochromis_polyacanthus
ENSG00000138385SSB10097.283ENSAMEG00000010507SSB10090.544Ailuropoda_melanoleuca
ENSG00000138385SSB9864.407ENSACIG00000001738ssb9757.754Amphilophus_citrinellus
ENSG00000138385SSB9865.254ENSAOCG00000020398ssb10055.012Amphiprion_ocellaris
ENSG00000138385SSB9866.102ENSAPEG00000020395ssb10055.501Amphiprion_percula
ENSG00000138385SSB9863.559ENSATEG00000016884ssb10057.213Anabas_testudineus
ENSG00000138385SSB10079.167ENSAPLG00000006109SSB10071.429Anas_platyrhynchos
ENSG00000138385SSB10073.333ENSACAG00000017008SSB9966.829Anolis_carolinensis
ENSG00000138385SSB10092.935ENSANAG00000027195-10088.480Aotus_nancymaae
ENSG00000138385SSB9865.254ENSACLG00000010798ssb10054.054Astatotilapia_calliptera
ENSG00000138385SSB9858.120ENSAMXG00000012606ssb10055.932Astyanax_mexicanus
ENSG00000138385SSB10098.370ENSBTAG00000008716SSB10093.627Bos_taurus
ENSG00000138385SSB8941.284WBGene00016653C44E4.49133.967Caenorhabditis_elegans
ENSG00000138385SSB10099.167ENSCJAG00000045073SSB10097.304Callithrix_jacchus
ENSG00000138385SSB10097.500ENSCAFG00000012418SSB10093.888Canis_familiaris
ENSG00000138385SSB10097.500ENSCAFG00020002900SSB10093.888Canis_lupus_dingo
ENSG00000138385SSB10098.370ENSCHIG00000022624-10093.627Capra_hircus
ENSG00000138385SSB10095.109ENSCHIG00000022196-10087.990Capra_hircus
ENSG00000138385SSB10099.167ENSTSYG00000000097SSB10095.098Carlito_syrichta
ENSG00000138385SSB10098.370ENSCPOG00000003338SSB10095.588Cavia_porcellus
ENSG00000138385SSB100100.000ENSCCAG00000035147SSB10098.039Cebus_capucinus
ENSG00000138385SSB10072.549ENSCATG00000042909-10072.549Cercocebus_atys
ENSG00000138385SSB10076.961ENSCATG00000036701SSB10076.961Cercocebus_atys
ENSG00000138385SSB10097.826ENSCLAG00000015617-10094.853Chinchilla_lanigera
ENSG00000138385SSB8699.130ENSCLAG00000004563-9897.436Chinchilla_lanigera
ENSG00000138385SSB100100.000ENSCSAG00000015200SSB8998.775Chlorocebus_sabaeus
ENSG00000138385SSB10090.833ENSCSAG00000018390-10089.500Chlorocebus_sabaeus
ENSG00000138385SSB10098.370ENSCHOG00000007763SSB10094.118Choloepus_hoffmanni
ENSG00000138385SSB10084.167ENSCPBG00000006519SSB10079.462Chrysemys_picta_bellii
ENSG00000138385SSB10083.333ENSCANG00000033240-10083.088Colobus_angolensis_palliatus
ENSG00000138385SSB100100.000ENSCANG00000027695SSB10098.775Colobus_angolensis_palliatus
ENSG00000138385SSB9876.368ENSCANG00000028838-9576.368Colobus_angolensis_palliatus
ENSG00000138385SSB10092.391ENSCGRG00001024831Ssb10080.145Cricetulus_griseus_chok1gshd
ENSG00000138385SSB10092.391ENSCGRG00000005387Ssb10080.145Cricetulus_griseus_crigri
ENSG00000138385SSB9862.712ENSCSEG00000011599ssb9956.576Cynoglossus_semilaevis
ENSG00000138385SSB9864.407ENSCVAG00000021558ssb10057.073Cyprinodon_variegatus
ENSG00000138385SSB9860.169ENSDARG00000029252ssb9956.576Danio_rerio
ENSG00000138385SSB10097.283ENSDNOG00000013450SSB10093.627Dasypus_novemcinctus
ENSG00000138385SSB10094.565ENSDORG00000005543Ssb10084.783Dipodomys_ordii
ENSG00000138385SSB9839.837FBgn0011638La9234.555Drosophila_melanogaster
ENSG00000138385SSB10092.500ENSETEG00000004614-6194.030Echinops_telfairi
ENSG00000138385SSB10054.167ENSEBUG00000001237ssb9648.346Eptatretus_burgeri
ENSG00000138385SSB10099.167ENSEASG00005022835SSB10095.588Equus_asinus_asinus
ENSG00000138385SSB10099.167ENSECAG00000018495SSB10095.833Equus_caballus
ENSG00000138385SSB10097.500ENSEEUG00000008077SSB8689.286Erinaceus_europaeus
ENSG00000138385SSB10064.167ENSELUG00000020929ssb10059.512Esox_lucius
ENSG00000138385SSB10098.370ENSFCAG00000011601SSB10094.621Felis_catus
ENSG00000138385SSB10078.333ENSFALG00000000930SSB10074.817Ficedula_albicollis
ENSG00000138385SSB10098.333ENSFDAG00000000598SSB10094.608Fukomys_damarensis
ENSG00000138385SSB6867.073ENSFHEG00000003268ssb9654.369Fundulus_heteroclitus
ENSG00000138385SSB8668.696ENSFHEG00000003003-10067.797Fundulus_heteroclitus
ENSG00000138385SSB9861.538ENSGMOG00000002664ssb9954.902Gadus_morhua
ENSG00000138385SSB10079.167ENSGALG00000009677SSB10074.265Gallus_gallus
ENSG00000138385SSB9862.712ENSGAFG00000002749ssb10055.501Gambusia_affinis
ENSG00000138385SSB9863.559ENSGACG00000005107ssb10053.735Gasterosteus_aculeatus
ENSG00000138385SSB10082.500ENSGAGG00000007807SSB10078.240Gopherus_agassizii
ENSG00000138385SSB83100.000ENSGGOG00000011507-8899.231Gorilla_gorilla
ENSG00000138385SSB10081.618ENSGGOG00000024891-10081.618Gorilla_gorilla
ENSG00000138385SSB6596.552ENSGGOG00000023471-10096.552Gorilla_gorilla
ENSG00000138385SSB9865.254ENSHBUG00000006584ssb10053.563Haplochromis_burtoni
ENSG00000138385SSB10091.667ENSHGLG00000005832-10085.539Heterocephalus_glaber_female
ENSG00000138385SSB10088.333ENSHGLG00000004478-10086.585Heterocephalus_glaber_female
ENSG00000138385SSB10095.000ENSHGLG00000001810-8590.217Heterocephalus_glaber_female
ENSG00000138385SSB10097.500ENSHGLG00000017580-10093.494Heterocephalus_glaber_female
ENSG00000138385SSB8994.393ENSHGLG00000018387-10094.068Heterocephalus_glaber_female
ENSG00000138385SSB9786.923ENSHGLG00000011331-9892.949Heterocephalus_glaber_female
ENSG00000138385SSB10084.328ENSHGLG00100013137-7595.082Heterocephalus_glaber_male
ENSG00000138385SSB10097.500ENSHGLG00100003084-10093.494Heterocephalus_glaber_male
ENSG00000138385SSB8696.522ENSHGLG00100014205-8595.425Heterocephalus_glaber_male
ENSG00000138385SSB9887.179ENSHGLG00100008767-10081.618Heterocephalus_glaber_male
ENSG00000138385SSB9689.565ENSHGLG00100007213-8691.566Heterocephalus_glaber_male
ENSG00000138385SSB9687.500ENSHGLG00100006391-9788.372Heterocephalus_glaber_male
ENSG00000138385SSB7783.696ENSHGLG00100008353-6575.497Heterocephalus_glaber_male
ENSG00000138385SSB8693.913ENSHGLG00100003175-9993.162Heterocephalus_glaber_male
ENSG00000138385SSB9861.864ENSHCOG00000019011ssb9955.000Hippocampus_comes
ENSG00000138385SSB9865.812ENSIPUG00000003681SSB9957.960Ictalurus_punctatus
ENSG00000138385SSB10098.370ENSSTOG00000008416SSB10095.343Ictidomys_tridecemlineatus
ENSG00000138385SSB10094.565ENSJJAG00000023158-10080.282Jaculus_jaculus
ENSG00000138385SSB9991.597ENSJJAG00000016250-9968.642Jaculus_jaculus
ENSG00000138385SSB9866.102ENSKMAG00000017317ssb10056.235Kryptolebias_marmoratus
ENSG00000138385SSB9861.017ENSLBEG00000017345ssb10053.790Labrus_bergylta
ENSG00000138385SSB10075.000ENSLACG00000014056SSB9969.363Latimeria_chalumnae
ENSG00000138385SSB10072.500ENSLOCG00000007933ssb9966.749Lepisosteus_oculatus
ENSG00000138385SSB10098.333ENSLAFG00000000867-10088.471Loxodonta_africana
ENSG00000138385SSB10087.500ENSLAFG00000028909-10079.167Loxodonta_africana
ENSG00000138385SSB9972.269ENSLAFG00000026721-9969.536Loxodonta_africana
ENSG00000138385SSB10088.043ENSMFAG00000041478-10084.314Macaca_fascicularis
ENSG00000138385SSB100100.000ENSMFAG00000039066SSB10099.020Macaca_fascicularis
ENSG00000138385SSB10088.333ENSMMUG00000011724-9783.088Macaca_mulatta
ENSG00000138385SSB9968.719ENSMMUG00000039889-10068.966Macaca_mulatta
ENSG00000138385SSB100100.000ENSMMUG00000023051SSB10099.020Macaca_mulatta
ENSG00000138385SSB100100.000ENSMNEG00000028321SSB10097.059Macaca_nemestrina
ENSG00000138385SSB10088.043ENSMNEG00000034698-10084.314Macaca_nemestrina
ENSG00000138385SSB10070.343ENSMLEG00000042644-10070.343Mandrillus_leucophaeus
ENSG00000138385SSB100100.000ENSMLEG00000035717SSB10099.020Mandrillus_leucophaeus
ENSG00000138385SSB9865.254ENSMAMG00000004800ssb10057.702Mastacembelus_armatus
ENSG00000138385SSB9865.254ENSMZEG00005005749ssb10054.054Maylandia_zebra
ENSG00000138385SSB10079.167ENSMGAG00000010328SSB9975.610Meleagris_gallopavo
ENSG00000138385SSB8693.913ENSMAUG00000019529-9993.377Mesocricetus_auratus
ENSG00000138385SSB10099.167ENSMICG00000028252-9996.059Microcebus_murinus
ENSG00000138385SSB10099.167ENSMICG00000033304-9590.617Microcebus_murinus
ENSG00000138385SSB8693.043ENSMOCG00000001823-9992.715Microtus_ochrogaster
ENSG00000138385SSB9762.308ENSMMOG00000002088-9562.308Mola_mola
ENSG00000138385SSB9084.259ENSMODG00000019271-10067.402Monodelphis_domestica
ENSG00000138385SSB10086.667ENSMODG00000008227-10078.469Monodelphis_domestica
ENSG00000138385SSB9083.333ENSMODG00000007027-10081.761Monodelphis_domestica
ENSG00000138385SSB9865.254ENSMALG00000008045ssb9058.400Monopterus_albus
ENSG00000138385SSB10091.848MGP_CAROLIEiJ_G0023629-10091.848Mus_caroli
ENSG00000138385SSB10091.848ENSMUSG00000068882Ssb10091.848Mus_musculus
ENSG00000138385SSB10091.848MGP_PahariEiJ_G0025081-10091.848Mus_pahari
ENSG00000138385SSB10091.848MGP_SPRETEiJ_G0024551Ssb10091.848Mus_spretus
ENSG00000138385SSB10098.333ENSMPUG00000000785SSB10094.608Mustela_putorius_furo
ENSG00000138385SSB10098.333ENSMLUG00000016316SSB10089.362Myotis_lucifugus
ENSG00000138385SSB9192.683ENSNGAG00000012920-8892.683Nannospalax_galili
ENSG00000138385SSB9865.254ENSNBRG00000012661ssb10054.054Neolamprologus_brichardi
ENSG00000138385SSB100100.000ENSNLEG00000004958SSB100100.000Nomascus_leucogenys
ENSG00000138385SSB10073.913ENSNLEG00000028754-10070.416Nomascus_leucogenys
ENSG00000138385SSB10085.833ENSMEUG00000001650-10087.097Notamacropus_eugenii
ENSG00000138385SSB6398.333ENSOPRG00000008479-7096.429Ochotona_princeps
ENSG00000138385SSB7275.768ENSOPRG00000008475-10075.768Ochotona_princeps
ENSG00000138385SSB8888.571ENSODEG00000006639-10072.527Octodon_degus
ENSG00000138385SSB10096.667ENSODEG00000004202-10088.976Octodon_degus
ENSG00000138385SSB10097.826ENSODEG00000010185-10097.838Octodon_degus
ENSG00000138385SSB8891.509ENSODEG00000010041-9988.406Octodon_degus
ENSG00000138385SSB9864.407ENSONIG00000008776ssb10053.563Oreochromis_niloticus
ENSG00000138385SSB10090.000ENSOANG00000008543SSB10083.824Ornithorhynchus_anatinus
ENSG00000138385SSB100100.000ENSOCUG00000010396SSB10094.853Oryctolagus_cuniculus
ENSG00000138385SSB9869.492ENSORLG00000017208ssb10057.702Oryzias_latipes
ENSG00000138385SSB9869.492ENSORLG00020022574ssb10057.702Oryzias_latipes_hni
ENSG00000138385SSB9868.644ENSORLG00015016592ssb10057.457Oryzias_latipes_hsok
ENSG00000138385SSB9866.949ENSOMEG00000003193ssb10058.578Oryzias_melastigma
ENSG00000138385SSB10098.333ENSOGAG00000029768SSB10089.647Otolemur_garnettii
ENSG00000138385SSB10098.370ENSOARG00000002906SSB10093.137Ovis_aries
ENSG00000138385SSB10080.392ENSPPAG00000032427-10087.597Pan_paniscus
ENSG00000138385SSB100100.000ENSPPAG00000042673SSB100100.000Pan_paniscus
ENSG00000138385SSB9694.783ENSPPAG00000006189-9680.800Pan_paniscus
ENSG00000138385SSB10098.370ENSPPRG00000006599SSB10094.621Panthera_pardus
ENSG00000138385SSB10098.333ENSPTIG00000011021SSB9794.377Panthera_tigris_altaica
ENSG00000138385SSB100100.000ENSPTRG00000012620SSB100100.000Pan_troglodytes
ENSG00000138385SSB10076.225ENSPTRG00000042880-10076.225Pan_troglodytes
ENSG00000138385SSB100100.000ENSPANG00000007440SSB10099.020Papio_anubis
ENSG00000138385SSB10069.118ENSPANG00000034126-10069.608Papio_anubis
ENSG00000138385SSB10070.109ENSPANG00000031877-9568.905Papio_anubis
ENSG00000138385SSB10068.333ENSPKIG00000019325ssb9962.010Paramormyrops_kingsleyae
ENSG00000138385SSB10079.167ENSPSIG00000002265SSB9375.795Pelodiscus_sinensis
ENSG00000138385SSB9660.000ENSPMGG00000020075ssb9155.014Periophthalmus_magnuspinnatus
ENSG00000138385SSB8694.783ENSPEMG00000021746-9994.040Peromyscus_maniculatus_bairdii
ENSG00000138385SSB9951.351ENSPMAG00000002982ssb10045.602Petromyzon_marinus
ENSG00000138385SSB8680.870ENSPCIG00000016333-9282.946Phascolarctos_cinereus
ENSG00000138385SSB10085.870ENSPCIG00000028591-10082.641Phascolarctos_cinereus
ENSG00000138385SSB9864.407ENSPFOG00000009650ssb10056.479Poecilia_formosa
ENSG00000138385SSB9864.407ENSPLAG00000020498ssb10055.990Poecilia_latipinna
ENSG00000138385SSB9863.559ENSPMEG00000001051ssb10055.990Poecilia_mexicana
ENSG00000138385SSB9861.864ENSPREG00000003708ssb9956.955Poecilia_reticulata
ENSG00000138385SSB100100.000ENSPPYG00000012919SSB10099.265Pongo_abelii
ENSG00000138385SSB10098.333ENSPCAG00000010276SSB10089.119Procavia_capensis
ENSG00000138385SSB10095.833ENSPCOG00000015741-10092.157Propithecus_coquereli
ENSG00000138385SSB86100.000ENSPCOG00000023189-10084.804Propithecus_coquereli
ENSG00000138385SSB10098.333ENSPVAG00000006615SSB10093.838Pteropus_vampyrus
ENSG00000138385SSB9865.254ENSPNYG00000006444ssb10054.054Pundamilia_nyererei
ENSG00000138385SSB9863.248ENSPNAG00000011708ssb10057.561Pygocentrus_nattereri
ENSG00000138385SSB10090.217ENSRNOG00000011606AABR07061825.110077.859Rattus_norvegicus
ENSG00000138385SSB10092.391ENSRNOG00000007998Ssb10077.358Rattus_norvegicus
ENSG00000138385SSB10070.905ENSRBIG00000029918-10070.905Rhinopithecus_bieti
ENSG00000138385SSB10097.059ENSRBIG00000041972SSB10097.059Rhinopithecus_bieti
ENSG00000138385SSB9984.034ENSRBIG00000041232-9881.675Rhinopithecus_bieti
ENSG00000138385SSB96100.000ENSRBIG00000041608-9890.685Rhinopithecus_bieti
ENSG00000138385SSB96100.000ENSRROG00000034102-9889.027Rhinopithecus_roxellana
ENSG00000138385SSB9984.034ENSRROG00000031684-10082.707Rhinopithecus_roxellana
ENSG00000138385SSB10080.685ENSRROG00000007149-10080.685Rhinopithecus_roxellana
ENSG00000138385SSB100100.000ENSRROG00000040346SSB10098.775Rhinopithecus_roxellana
ENSG00000138385SSB100100.000ENSSBOG00000027204SSB10098.529Saimiri_boliviensis_boliviensis
ENSG00000138385SSB10086.667ENSSHAG00000018062SSB10082.927Sarcophilus_harrisii
ENSG00000138385SSB10070.833ENSSFOG00015000550ssb10064.407Scleropages_formosus
ENSG00000138385SSB9862.712ENSSMAG00000013885ssb9956.952Scophthalmus_maximus
ENSG00000138385SSB9863.559ENSSDUG00000020117ssb10056.479Seriola_dumerili
ENSG00000138385SSB9862.712ENSSLDG00000002525ssb10054.926Seriola_lalandi_dorsalis
ENSG00000138385SSB8794.231ENSSARG00000007747SSB10084.715Sorex_araneus
ENSG00000138385SSB10083.333ENSSPUG00000012112SSB10076.225Sphenodon_punctatus
ENSG00000138385SSB9864.407ENSSPAG00000005696ssb10055.257Stegastes_partitus
ENSG00000138385SSB10094.022ENSSSCG00000015938SSB9877.307Sus_scrofa
ENSG00000138385SSB10078.333ENSTGUG00000007942SSB10074.572Taeniopygia_guttata
ENSG00000138385SSB9863.559ENSTRUG00000017839ssb10056.618Takifugu_rubripes
ENSG00000138385SSB9865.254ENSTNIG00000000915ssb10059.239Tetraodon_nigroviridis
ENSG00000138385SSB86100.000ENSTBEG00000009056SSB82100.000Tupaia_belangeri
ENSG00000138385SSB10096.739ENSTTRG00000002152SSB10093.888Tursiops_truncatus
ENSG00000138385SSB10097.826ENSUAMG00000027833SSB9995.000Ursus_americanus
ENSG00000138385SSB10097.826ENSUMAG00000013907SSB10094.377Ursus_maritimus
ENSG00000138385SSB10098.333ENSVPAG00000007183SSB10093.627Vicugna_pacos
ENSG00000138385SSB10097.500ENSVVUG00000016573SSB7893.888Vulpes_vulpes
ENSG00000138385SSB9871.186ENSXETG00000025402ssb10060.140Xenopus_tropicalis
ENSG00000138385SSB9861.017ENSXCOG00000019109ssb9361.719Xiphophorus_couchianus
ENSG00000138385SSB9861.864ENSXMAG00000004888ssb10055.257Xiphophorus_maculatus
Gene Ontology
Go IDGo_termPubmedIDEvidenceCategory
GO:0000049tRNA binding10983981.IMPFunction
GO:0000784nuclear chromosome, telomeric region19135898.HDAComponent
GO:0001682tRNA 5'-leader removal10983981.IGIProcess
GO:0003723RNA binding22658674.22681889.HDAFunction
GO:0003723RNA binding3192525.IMPFunction
GO:0003729mRNA binding9154801.TASFunction
GO:0005515protein binding23552417.24965446.25616068.IPIFunction
GO:0005634nucleus17308035.24965446.IDAComponent
GO:0005737cytoplasm17308035.IDAComponent
GO:0006400tRNA modification10983981.TASProcess
GO:0006409tRNA export from nucleus17308035.IMPProcess
GO:0008033tRNA processing17308035.IMPProcess
GO:0008266poly(U) RNA binding12842046.15004549.16387655.IMPFunction
GO:0008334histone mRNA metabolic process9154801.TASProcess
GO:0042780tRNA 3'-end processing10983981.IGIProcess
GO:0042803protein homodimerization activity12842046.IMPFunction
GO:0071045nuclear histone mRNA catabolic process9154801.IMPProcess
GO:0075522IRES-dependent viral translational initiation12384597.IDAProcess
GO:1903608protein localization to cytoplasmic stress granule24965446.IDAProcess
GO:1990825sequence-specific mRNA binding9154801.IMPFunction
GO:1990904ribonucleoprotein complex-IEAComponent
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