18366743 | The evolution of core proteins involved in microRNA biogenesis. | BMC Evol Biol | 2008 Mar 25 | Murphy D | doi: 10.1186/1471-2148-8-92. |
9034343 | Oncogenic potential of TAR RNA binding protein TRBP and its regulatory interaction with RNA-dependent protein kinase PKR. | EMBO J | 1997 Feb 3 | Benkirane M | - |
25630541 | Dissecting the roles of TRBP and PACT in double-stranded RNA recognition and processing of noncoding RNAs. | Wiley Interdiscip Rev RNA | 2015 May-Jun | Heyam A | doi: 10.1002/wrna.1272 |
24954387 | 'Black sheep' that don't leave the double-stranded RNA-binding domain fold. | Trends Biochem Sci | 2014 Jul | Gleghorn ML | doi: 10.1016/j.tibs.2014.05.003 |
24561616 | Interactions between the non-seed region of siRNA and RNA-binding RLC/RISC proteins, Ago and TRBP, in mammalian cells. | Nucleic Acids Res | 2014 Apr | Takahashi T | doi: 10.1093/nar/gku153 |
21368194 | Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing. | Proc Natl Acad Sci U S A | 2011 Mar 15 | Melo S | doi: 10.1073/pnas.1014720108 |
23776147 | Processing of virus-derived cytoplasmic primary-microRNAs. | Wiley Interdiscip Rev RNA | 2013 Jul-Aug | Shapiro JS | doi: 10.1002/wrna.1169 |
16936726 | Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cells. | Nat Struct Mol Biol | 2006 Sep | Kim DH | - |
11725069 | Expression of TAR RNA-Binding Protein in Baculovirus and Co-Immunoprecipitation with Insect Cell Protein Kinase. | J Biomed Sci | 1995 Oct | Blair ED | - |
11641396 | Organization of the human tarbp2 gene reveals two promoters that are repressed in an astrocytic cell line. | J Biol Chem | 2001 Dec 28 | Bannwarth S | - |
16424907 | The role of PACT in the RNA silencing pathway. | EMBO J | 2006 Feb 8 | Lee Y | - |
15918770 | Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein. | PLoS Biol | 2005 Jul | Forstemann K | - |
19219043 | A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function. | Nat Genet | 2009 Mar | Melo SA | doi: 10.1038/ng.317 |
22279564 | TRBP and eIF6 homologue in Marsupenaeus japonicus play crucial roles in antiviral response. | PLoS One | 2012 | Wang S | doi: 10.1371/journal.pone.0030057 |
21937648 | The cellular TAR RNA binding protein, TRBP, promotes HIV-1 replication primarily by inhibiting the activation of double-stranded RNA-dependent kinase PKR. | J Virol | 2011 Dec | Sanghvi VR | doi: 10.1128/JVI.05240-11 |
21711701 | A proteomic study of TAR-RNA binding protein (TRBP)-associated factors. | Cell Biosci | 2011 Feb 25 | Chi YH | doi: 10.1186/2045-3701-1-9. |
20932845 | Substrate-specific kinetics of Dicer-catalyzed RNA processing. | J Mol Biol | 2010 Dec 3 | Chakravarthy S | doi: 10.1016/j.jmb.2010.09.030 |
25544363 | Regulatory networks between neurotrophins and miRNAs in brain diseases and cancers. | Acta Pharmacol Sin | 2015 Feb | Shi J | doi: 10.1038/aps.2014.135 |
24563327 | Up-regulation and worse prognostic marker of cytoplasmic TARBP2 expression in obstinate breast cancer. | Med Oncol | 2014 Apr | Lin X | doi: 10.1007/s12032-014-0868-9 |
23690119 | Microsatellite instability and TARBP2 mutation study in upper urinary tract urothelial carcinoma. | Am J Clin Pathol | 2013 Jun | Bai S | doi: 10.1309/AJCPBSLP8XHSWLOW. |
23661684 | Differential roles of human Dicer-binding proteins TRBP and PACT in small RNA processing. | Nucleic Acids Res | 2013 Jul | Lee HY | doi: 10.1093/nar/gkt361 |
23531496 | Multiple sensors ensure guide strand selection in human RNAi pathways. | RNA | 2013 May | Noland CL | doi: 10.1261/rna.037424.112 |
28096385 | Correction for Melo et al., Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing. | Proc Natl Acad Sci U S A | 2017 Jan 24 | - | doi: 10.1073/pnas.1621028114 |
26948382 | A designed recombinant fusion protein for targeted delivery of siRNA to the mouse brain. | J Control Release | 2016 Apr 28 | Haroon MM | doi: 10.1016/j.jconrel.2016.03.007 |
27599909 | shRNAmediated silencing of TARBP2 inhibits NCIH1299 nonsmall cell lung cancer cell invasion and migration via the JNK/STAT3/AKT pathway. | Mol Med Rep | 2016 Oct | Shi Y | doi: 10.3892/mmr.2016.5723 |
29445910 | 1H, 13C and 15N resonance assignment of domain 1 of trans-activation response element (TAR) RNA binding protein isoform 1 (TRBP2) and its comparison with that of isoform 2 (TRBP1). | Biomol NMR Assign | 2018 Apr | Paithankar H | doi: 10.1007/s12104-018-9807-6 |
30759864 | TARBP2-Enhanced Resistance during Tamoxifen Treatment in Breast Cancer. | Cancers (Basel) | 2019 Feb 12 | Wang MY | doi: 10.3390/cancers11020210. |
30927622 | TARBP2 inhibits IRF7 activation by suppressing TRAF6-mediated K63-linked ubiquitination of IRF7. | Mol Immunol | 2019 May | Ling T | doi: 10.1016/j.molimm.2019.02.019 |
19458189 | Hsp90 regulates the function of argonaute 2 and its recruitment to stress granules and P-bodies. | Mol Biol Cell | 2009 Jul | Pare JM | doi: 10.1091/mbc.E09-01-0082 |
19106622 | The NFAR's (nuclear factors associated with dsRNA): evolutionarily conserved members of the dsRNA binding protein family. | RNA Biol | 2009 Jan-Mar | Barber GN | - |
18948111 | dsRNA binding properties of RDE-4 and TRBP reflect their distinct roles in RNAi. | J Mol Biol | 2008 Dec 26 | Parker GS | doi: 10.1016/j.jmb.2008.10.002 |
17452327 | Human TRBP and PACT directly interact with each other and associate with dicer to facilitate the production of small interfering RNA. | J Biol Chem | 2007 Jun 15 | Kok KH | - |
25467938 | Double-stranded RNA in the biological control of grain aphid (Sitobion avenae F.). | Funct Integr Genomics | 2015 Mar | Wang D | doi: 10.1007/s10142-014-0424-x |
30347765 | Virus Sensor RIG-I Represses RNA Interference by Interacting with TRBP through LGP2 in Mammalian Cells. | Genes (Basel) | 2018 Oct 19 | Takahashi T | doi: 10.3390/genes9100511. |
15123692 | Merlin, a tumor suppressor, interacts with transactivation-responsive RNA-binding protein and inhibits its oncogenic activity. | J Biol Chem | 2004 Jul 16 | Lee JY | - |
25720988 | Conformation-dependent binding and tumor-targeted delivery of siRNA by a designed TRBP2: Affibody fusion protein. | Nanomedicine | 2015 Aug | Dar GH | doi: 10.1016/j.nano.2015.01.017 |
9230068 | Xlrbpa, a double-stranded RNA-binding protein associated with ribosomes and heterogeneous nuclear RNPs. | J Cell Biol | 1997 Jul 28 | Eckmann CR | - |
16629595 | Are viral-encoded microRNAs mediating latent HIV-1 infection? | DNA Cell Biol | 2006 Apr | Weinberg MS | - |
11438532 | Two dimerization domains in the trans-activation response RNA-binding protein (TRBP) individually reverse the protein kinase R inhibition of HIV-1 long terminal repeat expression. | J Biol Chem | 2001 Sep 7 | Daher A | - |
19820710 | Structural insights into RNA processing by the human RISC-loading complex. | Nat Struct Mol Biol | 2009 Nov | Wang HW | doi: 10.1038/nsmb.1673 |
19422693 | Characterization of the TRBP domain required for dicer interaction and function in RNA interference. | BMC Mol Biol | 2009 May 7 | Daniels SM | doi: 10.1186/1471-2199-10-38. |
23006623 | TRBP alters human precursor microRNA processing in vitro. | RNA | 2012 Nov | Lee HY | doi: 10.1261/rna.035501.112 |
22875687 | Backbone resonance assignments of the micro-RNA precursor binding region of human TRBP. | Biomol NMR Assign | 2013 Oct | Benoit MP | doi: 10.1007/s12104-012-9416-8 |
17360756 | Small interfering RNAs against the TAR RNA binding protein, TRBP, a Dicer cofactor, inhibit human immunodeficiency virus type 1 long terminal repeat expression and viral production. | J Virol | 2007 May | Christensen HS | - |
25668122 | HIV-1 RRE RNA acts as an RNA silencing suppressor by competing with TRBP-bound siRNAs. | RNA Biol | 2015 | Daniels SM | doi: 10.1080/15476286.2015.1014759. |
25064266 | HIV-1 translation and its regulation by cellular factors PKR and PACT. | Virus Res | 2014 Nov 26 | Burugu S | doi: 10.1016/j.virusres.2014.07.014 |
24352449 | Arabidopsis double-stranded RNA binding protein DRB3 participates in methylation-mediated defense against geminiviruses. | J Virol | 2014 Mar | Raja P | doi: 10.1128/JVI.02305-13 |
23658827 | Distinguishable in vitro binding mode of monomeric TRBP and dimeric PACT with siRNA. | PLoS One | 2013 May 2 | Takahashi T | doi: 10.1371/journal.pone.0063434 |
26221025 | Dengue NS3, an RNAi suppressor, modulates the human miRNA pathways through its interacting partner. | Biochem J | 2015 Oct 1 | Kakumani PK | doi: 10.1042/BJ20150445 |
29540527 | A biosensor for MAPK-dependent Lin28 signaling. | Mol Biol Cell | 2018 May 15 | Oldach LM | doi: 10.1091/mbc.E17-08-0500 |
30285465 | Sepiapterin alleviates impaired gastric nNOS function in spontaneous diabetic female rodents through NRF2 mRNA turnover and miRNA biogenesis pathway. | Am J Physiol Gastrointest Liver Physiol | 2018 Dec 1 | Gangula PR | doi: 10.1152/ajpgi.00152.2018 |
31300274 | Nuclear TARBP2 Drives Oncogenic Dysregulation of RNA Splicing and Decay. | Mol Cell | 2019 Jun 25 | Fish L | doi: 10.1016/j.molcel.2019.06.001 |
12475984 | The TAR RNA-binding protein, TRBP, stimulates the expression of TAR-containing RNAs in vitro and in vivo independently of its ability to inhibit the dsRNA-dependent kinase PKR. | J Biol Chem | 2003 Feb 14 | Dorin D | - |
14585207 | Additive activity between the trans-activation response RNA-binding protein, TRBP2, and cyclin T1 on HIV type 1 expression and viral production in murine cells. | AIDS Res Hum Retroviruses | 2003 Sep | Battisti PL | - |
25557550 | Dicer-TRBP complex formation ensures accurate mammalian microRNA biogenesis. | Mol Cell | 2015 Feb 5 | Wilson RC | doi: 10.1016/j.molcel.2014.11.030 |
25043050 | Metastasis-suppressor transcript destabilization through TARBP2 binding of mRNA hairpins. | Nature | 2014 Sep 11 | Goodarzi H | doi: 10.1038/nature13466 |
23435228 | The RNA-binding region of human TRBP interacts with microRNA precursors through two independent domains. | Nucleic Acids Res | 2013 Apr | Benoit MP | doi: 10.1093/nar/gkt086 |
29939295 | LGP2 virus sensor regulates gene expression network mediated by TRBP-bound microRNAs. | Nucleic Acids Res | 2018 Sep 28 | Takahashi T | doi: 10.1093/nar/gky575. |
2011739 | Characterization of a human TAR RNA-binding protein that activates the HIV-1 LTR. | Science | 1991 Mar 29 | Gatignol A | - |
9060615 | Specific repression of Tax trans-activation by TAR RNA-binding protein TRBP. | J Virol | 1997 Apr | Donzeau M | - |
10369260 | A double-stranded RNA binding protein required for activation of repressed messages in mammalian germ cells. | Nat Genet | 1999 Jun | Zhong J | - |
16343534 | Cell-specific regulation of TRBP1 promoter by NF-Y transcription factor in lymphocytes and astrocytes. | J Mol Biol | 2006 Feb 3 | Bannwarth S | - |
10849508 | Temporal control of protein synthesis during spermatogenesis. | Int J Androl | 2000 | Braun RE | - |
16253139 | Dual role of TRBP in HIV replication and RNA interference: viral diversion of a cellular pathway or evasion from antiviral immunity? | Retrovirology | 2005 Oct 27 | Gatignol A | - |
16271387 | Human RISC couples microRNA biogenesis and posttranscriptional gene silencing. | Cell | 2005 Nov 18 | Gregory RI | - |
16188979 | Low TRBP levels support an innate human immunodeficiency virus type 1 resistance in astrocytes by enhancing the PKR antiviral response. | J Virol | 2005 Oct | Ong CL | - |
16142218 | TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing. | EMBO Rep | 2005 Oct | Haase AD | - |
20184375 | Recognition of siRNA asymmetry by TAR RNA binding protein. | Biochemistry | 2010 Apr 13 | Gredell JA | doi: 10.1021/bi902189s. |
19605474 | ADAR1 interacts with PKR during human immunodeficiency virus infection of lymphocytes and contributes to viral replication. | J Virol | 2009 Oct | Clerzius G | doi: 10.1128/JVI.02457-08 |
19301657 | Protein components of the microRNA pathway and human diseases. | Methods Mol Biol | 2009 | Perron MP | doi: 10.1007/978-1-60327-547-7_18. |
18936160 | TRBP control of PACT-induced phosphorylation of protein kinase R is reversed by stress. | Mol Cell Biol | 2009 Jan | Daher A | doi: 10.1128/MCB.01030-08 |
18421256 | Interactions between the double-stranded RNA-binding proteins TRBP and PACT define the Medipal domain that mediates protein-protein interactions. | RNA Biol | 2008 Apr-Jun | Laraki G | - |
22933564 | The multiple functions of TRBP, at the hub of cell responses to viruses, stress, and cancer. | Microbiol Mol Biol Rev | 2012 Sep | Daniels SM | doi: 10.1128/MMBR.00012-12. |
22025453 | Expression levels of the microRNA maturing microprocessor complex component DGCR8 and the RNA-induced silencing complex (RISC) components argonaute-1, argonaute-2, PACT, TARBP1, and TARBP2 in epithelial skin cancer. | Mol Carcinog | 2012 Nov | Sand M | doi: 10.1002/mc.20861 |
21294215 | Multiple levels of PKR inhibition during HIV-1 replication. | Rev Med Virol | 2011 Jan | Clerzius G | doi: 10.1002/rmv.674 |
23207479 | Isolation and characterization of homologous TRBP cDNA for RNA interference in Penaeus monodon. | Fish Shellfish Immunol | 2013 Feb | Yang L | doi: 10.1016/j.fsi.2012.11.022 |
20462493 | Structure of Arabidopsis HYPONASTIC LEAVES1 and its molecular implications for miRNA processing. | Structure | 2010 May 12 | Yang SW | doi: 10.1016/j.str.2010.02.006. |
25725290 | Early growth response gene 1, a TRBP binding protein, is involved in miRNA activity of miR-125a-3p in human cells. | Cell Signal | 2015 Jun | Wei J | doi: 10.1016/j.cellsig.2015.02.016 |
25421511 | Stress-related alcohol consumption in heavy drinkers correlates with expression of miR-10a, miR-21, and components of the TAR-RNA-binding protein-associated complex. | Alcohol Clin Exp Res | 2014 Nov | Beech RD | doi: 10.1111/acer.12549. |
25110015 | Regulation of miRNA strand selection: follow the leader? | Biochem Soc Trans | 2014 Aug | Meijer HA | doi: 10.1042/BST20140142. |
27980417 | Clinicopathological Significance of TARBP2, APP, and ZNF395 in Breast Cancer. | Breast Cancer (Auckl) | 2016 Dec 8 | Oi R | - |
24141778 | Ribosomal proteins L5 and L11 co-operatively inactivate c-Myc via RNA-induced silencing complex. | Oncogene | 2014 Oct 9 | Liao JM | doi: 10.1038/onc.2013.430 |
24020926 | The PKR activator, PACT, becomes a PKR inhibitor during HIV-1 replication. | Retrovirology | 2013 Sep 11 | Clerzius G | doi: 10.1186/1742-4690-10-96. |
23511973 | The rough endoplasmatic reticulum is a central nucleation site of siRNA-mediated RNA silencing. | EMBO J | 2013 Apr 17 | Stalder L | doi: 10.1038/emboj.2013.52 |
26486325 | The role of TARBP2 in the development and progression of cancers. | Tumour Biol | 2016 Jan | Yu X | doi: 10.1007/s13277-015-4273-6 |
28174252 | TRBP maintains mammalian embryonic neural stem cell properties by acting as a novel transcriptional coactivator of the Notch signaling pathway. | Development | 2017 Mar 1 | Byun SH | doi: 10.1242/dev.139493 |
26029872 | Trbp regulates heart function through microRNA-mediated Sox6 repression. | Nat Genet | 2015 Jul | Ding J | doi: 10.1038/ng.3324 |
26012717 | Morphine Promotes Astrocyte-Preferential Differentiation of Mouse Hippocampal Progenitor Cells via PKC-epsilon-Dependent ERK Activation and TRBP Phosphorylation. | Stem Cells | 2015 Sep | Xu C | doi: 10.1002/stem.2055 |
25843719 | A critical role for PKR complexes with TRBP in Immunometabolic regulation and eIF2-and-alpha; phosphorylation in obesity. | Cell Rep | 2015 Apr 14 | Nakamura T | doi: 10.1016/j.celrep.2015.03.021 |
28634830 | The microRNA effector RNA-induced silencing complex in hidradenitis suppurativa: a significant dysregulation within active inflammatory lesions. | Arch Dermatol Res | 2017 Sep | Hessam S | doi: 10.1007/s00403-017-1752-1 |
29040648 | Molecular basis for asymmetry sensing of siRNAs by the Drosophila Loqs-PD/Dcr-2 complex in RNA interference. | Nucleic Acids Res | 2017 Dec 1 | Tants JN | doi: 10.1093/nar/gkx886. |
29045748 | Conserved asymmetry underpins homodimerization of Dicer-associated double-stranded RNA-binding proteins. | Nucleic Acids Res | 2017 Dec 1 | Heyam A | doi: 10.1093/nar/gkx928. |
29231267 | Contribution of the two dsRBM motifs to the double-stranded RNA binding and protein interactions of PACT. | J Cell Biochem | 2018 Apr | Chukwurah E | doi: 10.1002/jcb.26561 |
29348664 | Stress-induced TRBP phosphorylation enhances its interaction with PKR to regulate cellular survival. | Sci Rep | 2018 Jan 18 | Chukwurah E | doi: 10.1038/s41598-018-19360-8. |
29449323 | Structural basis of siRNA recognition by TRBP double-stranded RNA binding domains. | EMBO J | 2018 Mar 15 | Masliah G | doi: 10.15252/embj.201797089 |
30390472 | TARBP2 negatively regulates IFN--and-beta; production and innate antiviral response by targeting MAVS. | Mol Immunol | 2018 Dec | Ling T | doi: 10.1016/j.molimm.2018.10.017 |
30657254 | TARBP2-mediated destabilization of Nanog overcomes sorafenib resistance in hepatocellular carcinoma. | Mol Oncol | 2019 Apr | Lai HH | doi: 10.1002/1878-0261.12449 |
8723388 | Sequential steps in Tat trans-activation of HIV-1 mediated through cellular DNA, RNA, and protein binding factors. | Gene Expr | 1996 | Gatignol A | - |
7568151 | Double-stranded-RNA-dependent protein kinase and TAR RNA-binding protein form homo- and heterodimers in vivo. | Proc Natl Acad Sci U S A | 1995 Oct 10 | Cosentino GP | - |
11096080 | A Role of RNA Helicase A in cis-Acting Transactivation Response Element-mediated Transcriptional Regulation of Human Immunodeficiency Virus Type 1. | J Biol Chem | 2001 Feb 23 | Fujii R | - |
18267968 | Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect. | Nucleic Acids Res | 2008 Apr | Ui-Tei K | doi: 10.1093/nar/gkn042 |
21726814 | siRNA repositioning for guide strand selection by human Dicer complexes. | Mol Cell | 2011 Jul 8 | Noland CL | doi: 10.1016/j.molcel.2011.05.028. |
25608000 | Helical defects in microRNA influence protein binding by TAR RNA binding protein. | PLoS One | 2015 Jan 21 | Acevedo R | doi: 10.1371/journal.pone.0116749 |
25486461 | TARBP2 binding structured RNA elements drives metastasis. | Cell Cycle | 2014 | Goodarzi H | doi: 10.4161/15384101.2014.954453. |
28369725 | RNA Polymerase I Inhibition with CX-5461 as a Novel Therapeutic Strategy to Target MYC in Multiple Myeloma. | Br J Haematol | 2017 Apr | Lee HC | doi: 10.1111/bjh.14525. |