EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
25003198	The anoikis effector Bit1 displays tumor suppressive function in lung cancer cells.	PLoS One	2014 Jul 8	Yao X	doi: 10.1371/journal.pone.0101564
27655370	The Anoikis Effector Bit1 Inhibits EMT through Attenuation of TLE1-Mediated Repression of E-Cadherin in Lung Cancer Cells.	PLoS One	2016 Sep 21	Yao X	doi: 10.1371/journal.pone.0163228
21886829	Metastasis of tumor cells is enhanced by downregulation of Bit1.	PLoS One	2011	Karmali PP	doi: 10.1371/journal.pone.0023840
19578750	Down-regulation of the apoptosis-inducing factor or Bcl-2 inhibitor of transcription by RNA interference can alleviate TAp63gamma-induced apoptosis in esophageal squamous carcinoma EC9706 cells.	Int J Oncol	2009 Aug	Fan T	-

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr17	59697778	Missense_Mutation	NA	M67I	0.27	PTH2
BRCA	chr17	59707447	5'UTR	novel		0.28
BRCA	chr17	59699727	Intron	novel		0.24
BRCA	chr17	59697316	3'UTR	novel		0.22
BRCA	chr17	59697387	3'UTR	novel		0.6
CESC	chr17	59699121	Intron	novel		0.4
CESC	chr17	59699195	Intron	novel		0.13
CESC	chr17	59697967	In_Frame_Del	novel	K4del	0.15
CESC	chr17	59699454	Intron	novel		0.37
CESC	chr17	59699071	Intron	novel		0.37
COAD	chr17	59697865	Silent	NA	G38G	0.35
COAD	chr17	59698901	Intron	novel		0.32
COAD	chr17	59697764	Missense_Mutation	rs763966443	R72Q	0.37	PTH2
ESCA	chr17	59698946	Intron	novel		0.14
GBM	chr17	59697731	Missense_Mutation	rs774051081	A83V	0.24	PTH2
HNSC	chr17	59697664	Silent	novel	L105L	0.04
HNSC	chr17	59697713	Missense_Mutation	novel	A89V	0.13	PTH2
KIRC	chr17	59697936	Frame_Shift_Del	novel	*S15Vfs53**	0.15
KIRP	chr17	59697339	3'UTR	novel		0.44
LUSC	chr17	59697965	Missense_Mutation	novel	S5C	0.08
OV	chr17	59697851	Missense_Mutation	novel	S43N	0.09
PRAD	chr17	59697360	3'UTR	novel		0.29
PRAD	chr17	59697483	Missense_Mutation	NA	A166T	0.23	PTH2
SKCM	chr17	59697879	Nonsense_Mutation	NA	R34*	0.28
SKCM	chr17	59697781	Silent	NA	K66K	0.37
SKCM	chr17	59697529	Silent	NA	Q150Q	0.26
SKCM	chr17	59697504	Silent	NA	L159L	0.44
SKCM	chr17	59697727	Silent	NA	A84A	0.07
STAD	chr17	59697334	3'UTR	novel		0.21
STAD	chr17	59697845	Missense_Mutation	NA	T45M	0.33
STAD	chr17	59697792	Missense_Mutation	rs747089911	G63R	0.33
STAD	chr17	59697369	3'UTR	novel		0.2
STAD	chr17	59697934	Silent	rs746659595	S15S	0.23
UCEC	chr17	59697683	Missense_Mutation	NA	R99I	0.3	PTH2
UCEC	chr17	59699563	Intron	novel		0.38
UCEC	chr17	59699289	Intron	novel		0.34
UCEC	chr17	59697326	3'UTR	novel		0.17
UCEC	chr17	59699047	Intron	novel		0.2
UCEC	chr17	59698926	Intron	novel		0.48
UCEC	chr17	59699698	Intron	novel		0.39
UCEC	chr17	59697838	Missense_Mutation	novel	K47N	0.25
UCEC	chr17	59699250	Intron	novel		0.39
UCEC	chr17	59697928	Silent	rs147437736	L17L	0.39
UCEC	chr17	59699380	Intron	novel		0.4
UCEC	chr17	59699290	Intron	novel		0.28
UCEC	chr17	59697812	Missense_Mutation	novel	A56E	0.3
UCEC	chr17	59697835	Silent	novel	T48T	0.11
UCEC	chr17	59697765	Nonsense_Mutation	NA	R72*	0.2	PTH2
UCEC	chr17	59697463	Silent	novel	V172V	0.24
UCEC	chr17	59699568	Intron	novel		0.3
UCEC	chr17	59697764	Missense_Mutation	rs763966443	R72Q	0.34	PTH2
UCEC	chr17	59697794	Missense_Mutation	NA	S62I	0.23
UCEC	chr17	59697867	Missense_Mutation	novel	G38W	0.2
UCEC	chr17	59699699	Intron	novel		0.47

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BLCA	AMP	0.3725	0.00012456
CESC	DEL	0.0678	0.027508
DLBC	DEL	0.0208	0.18166
KIRP	AMP	0.6667	0.14801
KIRP	DEL	0.0035	0.054726
LUAD	DEL	0.0368	1.5526e-05
LUSC	DEL	0.0878	1.1877e-06
PAAD	DEL	0.212	0.035089
READ	AMP	0.1818	0.15915
READ	DEL	0.1333	0.23023
SARC	AMP	0.2023	0.032181
TGCT	DEL	0.06	0.0046229
THCA	DEL	0.002	0.221
UCS	DEL	0.1429	0.12448
UVM	AMP	0.1625	0.054583

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0001	Kaplan-Meier Survival Analysis
STAD	0.047	Kaplan-Meier Survival Analysis
MESO	0.036	Kaplan-Meier Survival Analysis
ACC	0.034	Kaplan-Meier Survival Analysis
HNSC	0.043	Kaplan-Meier Survival Analysis
LUSC	0.027	Kaplan-Meier Survival Analysis
KIRP	0.00021	Kaplan-Meier Survival Analysis
LIHC	0.00014	Kaplan-Meier Survival Analysis
LGG	0.033	Kaplan-Meier Survival Analysis
UVM	0.0001	Kaplan-Meier Survival Analysis
OV	0.0076	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000141378 (Gene tree)
Gene ID: 51651
Gene Symbol: PTRH2
Alias: BIT1|CGI-147|PTH2|CFAP37
Full Name: peptidyl-tRNA hydrolase 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 32,991 bases
Position: chr17:59,674,636-59,707,626
Accession: 24265
RBP type: canonical RBP
Summary: The protein encoded by this gene is a mitochondrial protein with two putative domains, an N-terminal mitochondrial localization sequence, and a UPF0099 domain. In vitro assays suggest that this protein possesses peptidyl-tRNA hydrolase activity, to release the peptidyl moiety from tRNA, thereby preventing the accumulation of dissociated peptidyl-tRNA that could reduce the efficiency of translation. This protein also plays a role regulating cell survival and death. It promotes survival as part of an integrin-signaling pathway for cells attached to the extracellular matrix (ECM), but also promotes apoptosis in cells that have lost their attachment to the ECM, a process called anoikos. After loss of cell attachment to the ECM, this protein is phosphorylated, is released from the mitochondria into the cytosol, and promotes caspase-independent apoptosis through interactions with transcriptional regulators. This gene has been implicated in the development and progression of tumors, and mutations in this gene have been associated with an infantile multisystem neurologic, endocrine, and pancreatic disease (INMEPD) characterized by intellectual disability, postnatal microcephaly, progressive cerebellar atrophy, hearing impairment, polyneuropathy, failure to thrive, and organ fibrosis with exocrine pancreas insufficiency (PMID: 25574476). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2015]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000376758	PTH2	PF01981.16	2.9e-47	1	1
ENSP00000464327	PTH2	PF01981.16	2.9e-47	1	1
ENSP00000387180	PTH2	PF01981.16	2.9e-47	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000579915	PTRH2-204	531	-	-	- (aa)	-	-
ENST00000470557	PTRH2-203	4114	-	ENSP00000464327	179 (aa)	-	Q9Y3E5
ENST00000393038	PTRH2-201	901	XM_011524887	ENSP00000376758	179 (aa)	XP_011523189	Q9Y3E5
ENST00000587935	PTRH2-205	409	-	-	- (aa)	-	-
ENST00000409433	PTRH2-202	2246	-	ENSP00000387180	180 (aa)	-	J3KQ48

Gene Model

Click here to download ENSG00000141378's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000141378's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000141378	PTRH2	96	73.410	ENSAPOG00000008379	ptrh2	98	73.410	Acanthochromis_polyacanthus
ENSG00000141378	PTRH2	96	73.410	ENSAPOG00000008893	-	100	73.410	Acanthochromis_polyacanthus
ENSG00000141378	PTRH2	100	87.709	ENSAMEG00000011479	PTRH2	93	87.709	Ailuropoda_melanoleuca
ENSG00000141378	PTRH2	83	77.181	ENSACIG00000004561	ptrh2	98	73.780	Amphilophus_citrinellus
ENSG00000141378	PTRH2	96	73.410	ENSAOCG00000002043	ptrh2	98	73.410	Amphiprion_ocellaris
ENSG00000141378	PTRH2	90	75.309	ENSAPEG00000014719	ptrh2	83	75.309	Amphiprion_percula
ENSG00000141378	PTRH2	100	70.391	ENSATEG00000004102	ptrh2	100	70.391	Anabas_testudineus
ENSG00000141378	PTRH2	99	69.663	ENSACAG00000012801	PTRH2	98	69.663	Anolis_carolinensis
ENSG00000141378	PTRH2	100	92.778	ENSANAG00000021542	PTRH2	100	92.778	Aotus_nancymaae
ENSG00000141378	PTRH2	75	78.832	ENSACLG00000025860	ptrh2	98	69.942	Astatotilapia_calliptera
ENSG00000141378	PTRH2	93	71.257	ENSAMXG00000025556	ptrh2	97	71.257	Astyanax_mexicanus
ENSG00000141378	PTRH2	100	84.916	ENSBTAG00000016710	PTRH2	100	84.916	Bos_taurus
ENSG00000141378	PTRH2	100	92.222	ENSCJAG00000001503	PTRH2	100	92.222	Callithrix_jacchus
ENSG00000141378	PTRH2	100	88.268	ENSCAFG00000017662	PTRH2	100	88.268	Canis_familiaris
ENSG00000141378	PTRH2	100	88.268	ENSCAFG00020026497	PTRH2	100	88.268	Canis_lupus_dingo
ENSG00000141378	PTRH2	100	84.358	ENSCHIG00000010059	PTRH2	100	84.358	Capra_hircus
ENSG00000141378	PTRH2	100	90.000	ENSTSYG00000033941	PTRH2	100	90.000	Carlito_syrichta
ENSG00000141378	PTRH2	100	84.916	ENSCAPG00000004268	PTRH2	100	84.916	Cavia_aperea
ENSG00000141378	PTRH2	100	84.358	ENSCPOG00000032354	PTRH2	100	84.358	Cavia_porcellus
ENSG00000141378	PTRH2	100	92.778	ENSCCAG00000018678	PTRH2	100	92.778	Cebus_capucinus
ENSG00000141378	PTRH2	100	96.667	ENSCATG00000043363	PTRH2	100	96.667	Cercocebus_atys
ENSG00000141378	PTRH2	100	84.916	ENSCLAG00000011379	PTRH2	100	84.916	Chinchilla_lanigera
ENSG00000141378	PTRH2	100	97.207	ENSCSAG00000000552	PTRH2	100	97.207	Chlorocebus_sabaeus
ENSG00000141378	PTRH2	100	84.358	ENSCHOG00000004503	PTRH2	100	84.358	Choloepus_hoffmanni
ENSG00000141378	PTRH2	93	72.892	ENSCPBG00000006143	PTRH2	99	72.892	Chrysemys_picta_bellii
ENSG00000141378	PTRH2	90	61.111	ENSCING00000002435	-	96	61.111	Ciona_intestinalis
ENSG00000141378	PTRH2	100	97.778	ENSCANG00000037379	PTRH2	100	97.778	Colobus_angolensis_palliatus
ENSG00000141378	PTRH2	99	81.564	ENSCGRG00001011782	Ptrh2	99	81.564	Cricetulus_griseus_chok1gshd
ENSG00000141378	PTRH2	99	81.564	ENSCGRG00000011007	-	99	81.564	Cricetulus_griseus_crigri
ENSG00000141378	PTRH2	99	56.983	ENSCGRG00000006519	-	99	56.983	Cricetulus_griseus_crigri
ENSG00000141378	PTRH2	97	70.520	ENSCSEG00000011617	ptrh2	94	70.520	Cynoglossus_semilaevis
ENSG00000141378	PTRH2	96	69.186	ENSCVAG00000016871	ptrh2	96	69.186	Cyprinodon_variegatus
ENSG00000141378	PTRH2	96	69.540	ENSDARG00000077339	ptrh2	99	69.540	Danio_rerio
ENSG00000141378	PTRH2	98	82.955	ENSDNOG00000031122	PTRH2	98	82.955	Dasypus_novemcinctus
ENSG00000141378	PTRH2	100	83.240	ENSDORG00000027376	Ptrh2	100	83.240	Dipodomys_ordii
ENSG00000141378	PTRH2	63	47.414	FBgn0038107	CG17327	83	47.414	Drosophila_melanogaster
ENSG00000141378	PTRH2	66	53.782	FBgn0026566	CG1307	76	49.645	Drosophila_melanogaster
ENSG00000141378	PTRH2	97	56.983	ENSEBUG00000003900	ptrh2	100	56.983	Eptatretus_burgeri
ENSG00000141378	PTRH2	100	84.916	ENSEASG00005002310	PTRH2	100	84.916	Equus_asinus_asinus
ENSG00000141378	PTRH2	100	84.358	ENSECAG00000003621	PTRH2	100	84.358	Equus_caballus
ENSG00000141378	PTRH2	98	68.750	ENSELUG00000023013	ptrh2	87	68.750	Esox_lucius
ENSG00000141378	PTRH2	100	87.151	ENSFCAG00000018969	PTRH2	100	87.151	Felis_catus
ENSG00000141378	PTRH2	96	69.101	ENSFALG00000015110	PTRH2	96	69.101	Ficedula_albicollis
ENSG00000141378	PTRH2	100	86.034	ENSFDAG00000011721	PTRH2	100	86.034	Fukomys_damarensis
ENSG00000141378	PTRH2	96	70.930	ENSFHEG00000015394	ptrh2	92	70.930	Fundulus_heteroclitus
ENSG00000141378	PTRH2	97	70.520	ENSGMOG00000020589	ptrh2	97	70.520	Gadus_morhua
ENSG00000141378	PTRH2	96	72.093	ENSGALG00000005150	PTRH2	100	72.093	Gallus_gallus
ENSG00000141378	PTRH2	100	66.851	ENSGAFG00000015503	ptrh2	99	66.851	Gambusia_affinis
ENSG00000141378	PTRH2	74	67.424	ENSGAGG00000024006	PTRH2	84	67.424	Gopherus_agassizii
ENSG00000141378	PTRH2	100	98.889	ENSGGOG00000007957	PTRH2	100	98.889	Gorilla_gorilla
ENSG00000141378	PTRH2	75	78.102	ENSHBUG00000017727	ptrh2	100	69.767	Haplochromis_burtoni
ENSG00000141378	PTRH2	100	84.916	ENSHGLG00000007335	PTRH2	100	84.916	Heterocephalus_glaber_female
ENSG00000141378	PTRH2	100	84.916	ENSHGLG00100011494	PTRH2	100	84.916	Heterocephalus_glaber_male
ENSG00000141378	PTRH2	96	63.372	ENSHCOG00000012325	ptrh2	98	63.372	Hippocampus_comes
ENSG00000141378	PTRH2	93	67.262	ENSIPUG00000019124	ptrh2	96	67.262	Ictalurus_punctatus
ENSG00000141378	PTRH2	100	86.592	ENSSTOG00000028844	PTRH2	100	86.592	Ictidomys_tridecemlineatus
ENSG00000141378	PTRH2	100	81.564	ENSJJAG00000019588	-	100	81.564	Jaculus_jaculus
ENSG00000141378	PTRH2	97	68.786	ENSJJAG00000015451	-	100	68.786	Jaculus_jaculus
ENSG00000141378	PTRH2	98	72.159	ENSKMAG00000013276	ptrh2	88	72.159	Kryptolebias_marmoratus
ENSG00000141378	PTRH2	96	74.419	ENSLBEG00000004103	ptrh2	90	74.419	Labrus_bergylta
ENSG00000141378	PTRH2	96	69.186	ENSLACG00000010258	PTRH2	96	69.186	Latimeria_chalumnae
ENSG00000141378	PTRH2	96	71.512	ENSLOCG00000017426	ptrh2	99	71.512	Lepisosteus_oculatus
ENSG00000141378	PTRH2	100	86.034	ENSLAFG00000031641	PTRH2	100	86.034	Loxodonta_africana
ENSG00000141378	PTRH2	100	96.667	ENSMFAG00000036307	PTRH2	100	96.667	Macaca_fascicularis
ENSG00000141378	PTRH2	100	97.222	ENSMMUG00000001572	PTRH2	100	97.222	Macaca_mulatta
ENSG00000141378	PTRH2	100	97.222	ENSMNEG00000037063	PTRH2	100	97.222	Macaca_nemestrina
ENSG00000141378	PTRH2	100	96.667	ENSMLEG00000028260	PTRH2	100	96.667	Mandrillus_leucophaeus
ENSG00000141378	PTRH2	96	68.605	ENSMAMG00000005245	ptrh2	98	68.605	Mastacembelus_armatus
ENSG00000141378	PTRH2	75	78.832	ENSMZEG00005023327	ptrh2	98	70.349	Maylandia_zebra
ENSG00000141378	PTRH2	99	70.000	ENSMGAG00000015485	PTRH2	99	70.000	Meleagris_gallopavo
ENSG00000141378	PTRH2	99	81.006	ENSMAUG00000022169	Ptrh2	99	81.006	Mesocricetus_auratus
ENSG00000141378	PTRH2	96	67.614	ENSMICG00000043977	-	97	67.614	Microcebus_murinus
ENSG00000141378	PTRH2	100	83.799	ENSMICG00000032675	-	100	83.333	Microcebus_murinus
ENSG00000141378	PTRH2	99	81.006	ENSMOCG00000018927	Ptrh2	99	81.006	Microtus_ochrogaster
ENSG00000141378	PTRH2	96	70.349	ENSMMOG00000005796	ptrh2	98	70.349	Mola_mola
ENSG00000141378	PTRH2	99	78.261	ENSMODG00000024517	PTRH2	99	78.261	Monodelphis_domestica
ENSG00000141378	PTRH2	96	71.512	ENSMALG00000001875	ptrh2	68	71.512	Monopterus_albus
ENSG00000141378	PTRH2	100	79.006	MGP_CAROLIEiJ_G0016918	Ptrh2	100	79.006	Mus_caroli
ENSG00000141378	PTRH2	100	79.006	ENSMUSG00000072582	Ptrh2	100	79.006	Mus_musculus
ENSG00000141378	PTRH2	100	77.901	MGP_PahariEiJ_G0018048	Ptrh2	100	77.901	Mus_pahari
ENSG00000141378	PTRH2	100	79.006	MGP_SPRETEiJ_G0017764	Ptrh2	100	79.006	Mus_spretus
ENSG00000141378	PTRH2	100	89.385	ENSMPUG00000019628	PTRH2	100	89.385	Mustela_putorius_furo
ENSG00000141378	PTRH2	100	86.592	ENSMLUG00000025120	PTRH2	100	86.592	Myotis_lucifugus
ENSG00000141378	PTRH2	100	83.240	ENSNGAG00000011147	Ptrh2	100	83.240	Nannospalax_galili
ENSG00000141378	PTRH2	97	70.690	ENSNBRG00000017781	ptrh2	94	70.690	Neolamprologus_brichardi
ENSG00000141378	PTRH2	100	97.778	ENSNLEG00000000792	PTRH2	100	97.778	Nomascus_leucogenys
ENSG00000141378	PTRH2	100	82.682	ENSOPRG00000019186	PTRH2	100	82.682	Ochotona_princeps
ENSG00000141378	PTRH2	100	83.799	ENSODEG00000020061	PTRH2	100	83.799	Octodon_degus
ENSG00000141378	PTRH2	96	71.512	ENSONIG00000020574	ptrh2	99	71.512	Oreochromis_niloticus
ENSG00000141378	PTRH2	100	76.536	ENSOANG00000008523	PTRH2	100	76.536	Ornithorhynchus_anatinus
ENSG00000141378	PTRH2	100	86.034	ENSOCUG00000023345	PTRH2	100	86.034	Oryctolagus_cuniculus
ENSG00000141378	PTRH2	70	81.600	ENSORLG00000012183	ptrh2	100	67.052	Oryzias_latipes
ENSG00000141378	PTRH2	70	81.600	ENSORLG00020015390	ptrh2	80	67.442	Oryzias_latipes_hni
ENSG00000141378	PTRH2	70	81.600	ENSORLG00015022173	ptrh2	80	67.052	Oryzias_latipes_hsok
ENSG00000141378	PTRH2	100	66.111	ENSOMEG00000011056	ptrh2	97	66.111	Oryzias_melastigma
ENSG00000141378	PTRH2	100	87.151	ENSOGAG00000026779	-	100	87.151	Otolemur_garnettii
ENSG00000141378	PTRH2	100	78.212	ENSOGAG00000027962	-	100	78.212	Otolemur_garnettii
ENSG00000141378	PTRH2	100	84.358	ENSOARG00000003891	PTRH2	100	84.358	Ovis_aries
ENSG00000141378	PTRH2	100	100.000	ENSPPAG00000032040	PTRH2	100	100.000	Pan_paniscus
ENSG00000141378	PTRH2	100	88.827	ENSPPRG00000018489	PTRH2	100	88.827	Panthera_pardus
ENSG00000141378	PTRH2	100	88.827	ENSPTIG00000004923	PTRH2	100	88.827	Panthera_tigris_altaica
ENSG00000141378	PTRH2	100	100.000	ENSPTRG00000009474	PTRH2	100	100.000	Pan_troglodytes
ENSG00000141378	PTRH2	100	97.222	ENSPANG00000022269	PTRH2	100	97.222	Papio_anubis
ENSG00000141378	PTRH2	91	71.779	ENSPKIG00000019982	ptrh2	98	71.779	Paramormyrops_kingsleyae
ENSG00000141378	PTRH2	99	70.056	ENSPSIG00000008890	PTRH2	98	70.056	Pelodiscus_sinensis
ENSG00000141378	PTRH2	96	69.767	ENSPMGG00000014486	ptrh2	97	71.098	Periophthalmus_magnuspinnatus
ENSG00000141378	PTRH2	99	80.447	ENSPEMG00000024186	Ptrh2	99	80.447	Peromyscus_maniculatus_bairdii
ENSG00000141378	PTRH2	98	75.410	ENSPCIG00000021876	PTRH2	98	75.410	Phascolarctos_cinereus
ENSG00000141378	PTRH2	97	68.182	ENSPFOG00000019981	ptrh2	97	68.182	Poecilia_formosa
ENSG00000141378	PTRH2	100	68.508	ENSPLAG00000017895	ptrh2	100	68.508	Poecilia_latipinna
ENSG00000141378	PTRH2	100	67.403	ENSPMEG00000013227	ptrh2	100	67.403	Poecilia_mexicana
ENSG00000141378	PTRH2	97	68.750	ENSPREG00000009062	ptrh2	97	68.750	Poecilia_reticulata
ENSG00000141378	PTRH2	100	98.324	ENSPPYG00000008810	PTRH2	100	98.324	Pongo_abelii
ENSG00000141378	PTRH2	100	84.358	ENSPCAG00000011420	PTRH2	100	84.358	Procavia_capensis
ENSG00000141378	PTRH2	100	85.556	ENSPCOG00000013419	PTRH2	100	85.556	Propithecus_coquereli
ENSG00000141378	PTRH2	100	86.034	ENSPVAG00000001542	PTRH2	100	86.034	Pteropus_vampyrus
ENSG00000141378	PTRH2	75	78.102	ENSPNYG00000021938	ptrh2	98	69.767	Pundamilia_nyererei
ENSG00000141378	PTRH2	100	70.718	ENSPNAG00000011617	ptrh2	100	70.718	Pygocentrus_nattereri
ENSG00000141378	PTRH2	100	79.558	ENSRNOG00000004288	Ptrh2	100	79.558	Rattus_norvegicus
ENSG00000141378	PTRH2	100	97.778	ENSRBIG00000033946	PTRH2	100	97.778	Rhinopithecus_bieti
ENSG00000141378	PTRH2	100	97.778	ENSRROG00000038107	PTRH2	100	97.778	Rhinopithecus_roxellana
ENSG00000141378	PTRH2	65	50.407	YBL057C	-	99	39.024	Saccharomyces_cerevisiae
ENSG00000141378	PTRH2	100	92.222	ENSSBOG00000021203	PTRH2	100	92.222	Saimiri_boliviensis_boliviensis
ENSG00000141378	PTRH2	98	76.923	ENSSHAG00000016608	PTRH2	98	76.923	Sarcophilus_harrisii
ENSG00000141378	PTRH2	100	68.715	ENSSFOG00015014530	ptrh2	100	68.715	Scleropages_formosus
ENSG00000141378	PTRH2	98	71.186	ENSSMAG00000000686	ptrh2	75	71.186	Scophthalmus_maximus
ENSG00000141378	PTRH2	97	72.414	ENSSDUG00000018478	ptrh2	90	72.414	Seriola_dumerili
ENSG00000141378	PTRH2	97	72.571	ENSSLDG00000020791	ptrh2	90	72.571	Seriola_lalandi_dorsalis
ENSG00000141378	PTRH2	99	69.663	ENSSPUG00000016349	PTRH2	100	69.663	Sphenodon_punctatus
ENSG00000141378	PTRH2	96	71.098	ENSSPAG00000006060	ptrh2	97	71.098	Stegastes_partitus
ENSG00000141378	PTRH2	100	86.034	ENSSSCG00000017667	PTRH2	100	86.034	Sus_scrofa
ENSG00000141378	PTRH2	93	69.643	ENSTGUG00000007610	PTRH2	100	69.643	Taeniopygia_guttata
ENSG00000141378	PTRH2	94	73.964	ENSTRUG00000008299	ptrh2	90	73.964	Takifugu_rubripes
ENSG00000141378	PTRH2	96	48.295	ENSTNIG00000003805	-	95	48.295	Tetraodon_nigroviridis
ENSG00000141378	PTRH2	93	68.824	ENSTNIG00000000826	PTRH2	95	68.824	Tetraodon_nigroviridis
ENSG00000141378	PTRH2	75	65.185	ENSTNIG00000005343	-	94	65.185	Tetraodon_nigroviridis
ENSG00000141378	PTRH2	93	68.675	ENSTNIG00000001658	-	95	68.675	Tetraodon_nigroviridis
ENSG00000141378	PTRH2	100	79.330	ENSTTRG00000017211	PTRH2	100	79.330	Tursiops_truncatus
ENSG00000141378	PTRH2	96	88.304	ENSUAMG00000009688	-	98	88.304	Ursus_americanus
ENSG00000141378	PTRH2	100	88.268	ENSUAMG00000009684	-	94	88.268	Ursus_americanus
ENSG00000141378	PTRH2	100	88.268	ENSUMAG00000022710	PTRH2	100	88.268	Ursus_maritimus
ENSG00000141378	PTRH2	100	85.475	ENSVPAG00000009365	PTRH2	100	85.475	Vicugna_pacos
ENSG00000141378	PTRH2	100	88.268	ENSVVUG00000018120	PTRH2	100	88.268	Vulpes_vulpes
ENSG00000141378	PTRH2	96	71.512	ENSXETG00000010737	ptrh2	100	71.512	Xenopus_tropicalis
ENSG00000141378	PTRH2	97	70.115	ENSXCOG00000004873	ptrh2	90	70.115	Xiphophorus_couchianus
ENSG00000141378	PTRH2	97	70.286	ENSXMAG00000020094	ptrh2	94	70.286	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0004045	aminoacyl-tRNA hydrolase activity	21873635.	IBA	Function
GO:0004045	aminoacyl-tRNA hydrolase activity	14660562.	IMP	Function
GO:0005515	protein binding	15006356.21383007.22952044.	IPI	Function
GO:0005739	mitochondrion	15006356.	IDA	Component
GO:0005739	mitochondrion	22952044.	IMP	Component
GO:0005829	cytosol	21873635.	IBA	Component
GO:0005829	cytosol	15006356.22952044.	IMP	Component
GO:0006915	apoptotic process	-	IEA	Process
GO:0010629	negative regulation of gene expression	15006356.	IMP	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:2000210	positive regulation of anoikis	15006356.22952044.	IMP	Process
GO:2000811	negative regulation of anoikis	21383007.	IMP	Process

EuRBPDB

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.