EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
28935813	ASXL3 Is a Novel Pluripotency Factor in Human Respiratory Epithelial Cells and a Potential Therapeutic Target in Small Cell Lung Cancer.	Cancer Res	2017 Nov 15	Shukla V	doi: 10.1158/0008-5472.CAN-17-0570

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr18	33743549	Missense_Mutation	novel	N1234I	0.41
ACC	chr18	33578655	Missense_Mutation	novel	K8N	0.59
ACC	chr18	33670714	Missense_Mutation	novel	M173I	0.86
ACC	chr18	33744047	Missense_Mutation	rs267605176	S1400C	0.06
ACC	chr18	33744596	Missense_Mutation	novel	A1583V	0.81
ACC	chr18	33739134	Missense_Mutation	novel	S577Y	0.32
ACC	chr18	33743041	Missense_Mutation	NA	R1065W	0.82
ACC	chr18	33743374	Silent	novel	R1176R	0.56
ACC	chr18	33745225	Missense_Mutation	novel	E1793Q	0.16
BLCA	chr18	33671836	Missense_Mutation	novel	H229Y	0.25
BLCA	chr18	33746266	Nonsense_Mutation	novel	Q2140*	0.24
BLCA	chr18	33739029	Missense_Mutation	novel	S542C	0.22
BLCA	chr18	33745671	Silent	novel	P1941P	0.68
BLCA	chr18	33746466	Silent	NA	A2206A	0.08
BLCA	chr18	33739016	Missense_Mutation	novel	E538Q	0.55
BLCA	chr18	33738588	Missense_Mutation	NA	S395C	0.07
BLCA	chr18	33743120	Missense_Mutation	novel	G1091A	0.2
BLCA	chr18	33743017	Missense_Mutation	novel	I1057F	0.32
BLCA	chr18	33731988	Silent	novel	L300L	0.41
BLCA	chr18	33740319	Missense_Mutation	novel	F972C	0.33
BLCA	chr18	33743182	Missense_Mutation	novel	A1112T	0.46
BLCA	chr18	33746631	3'UTR	rs756341246		0.08
BLCA	chr18	33743552	Missense_Mutation	NA	S1235F	0.05
BLCA	chr18	33746269	Missense_Mutation	NA	K2141E	0.29
BLCA	chr18	33739593	Missense_Mutation	NA	S730L	0.2
BLCA	chr18	33661706	Missense_Mutation	novel	F149Y	0.15
BLCA	chr18	33744085	Missense_Mutation	rs753966658	V1413I	0.05
BLCA	chr18	33745000	Missense_Mutation	NA	E1718K	0.1
BLCA	chr18	33744682	Missense_Mutation	novel	D1612N	0.38
BLCA	chr18	33738973	Silent	NA	S523S	0.5
BLCA	chr18	33744972	Missense_Mutation	NA	M1708I	0.44
BLCA	chr18	33745025	Missense_Mutation	rs369543627	A1726G	0.39
BLCA	chr18	33745405	Missense_Mutation	novel	D1853N	0.19
BLCA	chr18	33743672	Missense_Mutation	NA	S1275F	0.07
BLCA	chr18	33740229	Missense_Mutation	novel	S942L	0.1
BLCA	chr18	33743568	Silent	novel	V1240V	0.32
BRCA	chr18	33746120	Missense_Mutation	NA	S2091I	0.21
BRCA	chr18	33742989	Silent	rs766640644	R1047R	0.22
BRCA	chr18	33734348	Missense_Mutation	novel	E339K	0.07
BRCA	chr18	33740357	Missense_Mutation	NA	D985N	0.24
BRCA	chr18	33745101	Silent	NA	T1751T	0.15
BRCA	chr18	33646341	Missense_Mutation	NA	E115K	0.14
BRCA	chr18	33734365	Missense_Mutation	NA	K344N	0.26
BRCA	chr18	33744133	Missense_Mutation	novel	P1429T	0.48
BRCA	chr18	33746505	Silent	rs765224501	A2219A	0.14
BRCA	chr18	33739754	Missense_Mutation	NA	D784Y	0.15
BRCA	chr18	33743285	Missense_Mutation	NA	S1146F	0.09
BRCA	chr18	33744379	Missense_Mutation	rs200748841	V1511I	0.36
BRCA	chr18	33745000	Missense_Mutation	NA	E1718K	0.11
BRCA	chr18	33745556	Missense_Mutation	rs375291297	S1903L	0.17
BRCA	chr18	33734376	Missense_Mutation	NA	P348L	0.34
BRCA	chr18	33740349	Missense_Mutation	NA	I982K	0.39
BRCA	chr18	33746323	Missense_Mutation	novel	F2159V	0.09
BRCA	chr18	33746531	Missense_Mutation	novel	A2228V	0.08
BRCA	chr18	33670714	Missense_Mutation	NA	M173I	0.29
BRCA	chr18	33739250	Missense_Mutation	NA	E616Q	0.43
BRCA	chr18	33746591	Missense_Mutation	rs762444928	R2248Q	0.17
BRCA	chr18	33744179	Missense_Mutation	rs548755448	R1444Q	0.1
BRCA	chr18	33744960	Frame_Shift_Del	novel	Q1706*	0.24
BRCA	chr18	33745443	Silent	NA	I1865I	0.15
BRCA	chr18	33744465	Silent	novel	F1539F	0.07
BRCA	chr18	33745297	Missense_Mutation	novel	P1817T	0.3
CESC	chr18	33739931	Missense_Mutation	novel	D843H	0.17
CESC	chr18	33670698	Missense_Mutation	novel	R168I	0.32
CESC	chr18	33738911	Missense_Mutation	novel	V503L	0.32
CESC	chr18	33743051	Missense_Mutation	NA	R1068L	0.36
CESC	chr18	33745900	Frame_Shift_Ins	novel	*P2018Rfs30**	0.27
CESC	chr18	33670749	Missense_Mutation	novel	T185I	0.45
CESC	chr18	33739746	Missense_Mutation	rs201776257	P781L	0.28
CESC	chr18	33743793	Silent	novel	S1315S	0.46
CESC	chr18	33742954	Nonsense_Mutation	NA	R1036*	0.17
CESC	chr18	33744028	Missense_Mutation	novel	A1394T	0.3
CESC	chr18	33743510	Missense_Mutation	NA	S1221C	0.25
CESC	chr18	33739448	Missense_Mutation	novel	P682S	0.34
CHOL	chr18	33578648	Missense_Mutation	novel	K6R	0.36
COAD	chr18	33661729	Missense_Mutation	NA	L157I	0.32
COAD	chr18	33734391	Missense_Mutation	NA	F353S	0.35
COAD	chr18	33743781	Silent	NA	G1311G	0.49
COAD	chr18	33745092	Silent	rs750655781	P1748P	0.32
COAD	chr18	33732021	Missense_Mutation	NA	F311L	0.07
COAD	chr18	33745533	Silent	NA	K1895K	0.35
COAD	chr18	33743496	Missense_Mutation	NA	I1216M	0.48
COAD	chr18	33740022	Frame_Shift_Del	NA	*V876Cfs59**	0.41
COAD	chr18	33743972	Missense_Mutation	NA	A1375V	0.34
COAD	chr18	33745863	Silent	NA	T2005T	0.25
COAD	chr18	33740022	Frame_Shift_Del	NA	*V876Cfs59**	0.48
COAD	chr18	33740424	Missense_Mutation	NA	P1007L	0.41
COAD	chr18	33739558	Silent	rs370185733	P718P	0.6
COAD	chr18	33740204	Silent	NA	L934L	0.08
COAD	chr18	33744689	Missense_Mutation	NA	M1614T	0.25
COAD	chr18	33744479	Missense_Mutation	NA	A1544E	0.41
COAD	chr18	33745657	Missense_Mutation	rs763596943	A1937T	0.62
COAD	chr18	33746544	Silent	rs760578782	D2232D	0.5
COAD	chr18	33671858	Missense_Mutation	NA	S236Y	0.27
COAD	chr18	33745500	Missense_Mutation	NA	M1884I	0.3
COAD	chr18	33745908	Silent	rs369151165	P2020P	0.22
COAD	chr18	33743256	Missense_Mutation	NA	K1136N	0.33
COAD	chr18	33745899	Silent	rs779335040	P2017P	0.29
COAD	chr18	33745951	Frame_Shift_Del	NA	*P2037Hfs43**	0.33
COAD	chr18	33607650	Silent	NA	I37I	0.07
COAD	chr18	33732021	Missense_Mutation	NA	F311L	0.28
COAD	chr18	33734352	Missense_Mutation	novel	I340S	0.14
COAD	chr18	33738558	Missense_Mutation	NA	S385Y	0.14
COAD	chr18	33739562	Missense_Mutation	NA	S720P	0.13
COAD	chr18	33743552	Missense_Mutation	NA	S1235F	0.28
COAD	chr18	33734392	Missense_Mutation	NA	F353L	0.37
COAD	chr18	33746090	Missense_Mutation	rs200327794	S2081L	0.4
COAD	chr18	33743618	Missense_Mutation	NA	S1257Y	0.37
COAD	chr18	33740022	Frame_Shift_Del	NA	*V876Cfs59**	0.42
DLBC	chr18	33670772	Missense_Mutation	novel	Q193K	0.2
DLBC	chr18	33745097	Missense_Mutation	novel	V1750E	0.11
DLBC	chr18	33744313	Missense_Mutation	novel	V1489I	0.42
DLBC	chr18	33671862	Frame_Shift_Del	novel	L238*	0.05
DLBC	chr18	33745025	Missense_Mutation	novel	A1726D	0.25
DLBC	chr18	33746245	Missense_Mutation	novel	P2133S	0.07
DLBC	chr18	33743100	Silent	rs372707880	S1084S	0.21
ESCA	chr18	33661634	Missense_Mutation	novel	T125S	0.28
ESCA	chr18	33738571	Silent	novel	T389T	0.31
ESCA	chr18	33739682	Missense_Mutation	novel	I760L	0.16
ESCA	chr18	33745039	Missense_Mutation	novel	P1731T	0.38
ESCA	chr18	33739496	Missense_Mutation	novel	L698V	0.83
ESCA	chr18	33743124	Silent	novel	E1092E	0.19
ESCA	chr18	33739418	Missense_Mutation	novel	F672L	0.83
ESCA	chr18	33743988	Silent	novel	E1380E	0.25
ESCA	chr18	33743413	Missense_Mutation	rs761866641	S1189G	0.19
ESCA	chr18	33646251	Missense_Mutation	novel	E85Q	0.49
ESCA	chr18	33739232	Nonsense_Mutation	novel	E610*	0.39
ESCA	chr18	33738697	Missense_Mutation	novel	K431N	0.21
ESCA	chr18	33746216	Missense_Mutation	novel	S2123C	0.29
ESCA	chr18	33745106	Missense_Mutation	novel	L1753S	0.45
GBM	chr18	33744598	Missense_Mutation	rs755390840	R1584C	0.38
GBM	chr18	33744871	Missense_Mutation	novel	A1675T	0.04
GBM	chr18	33739553	Missense_Mutation	novel	S717T	0.12
GBM	chr18	33746003	Missense_Mutation	novel	S2052Y	0.4
GBM	chr18	33740370	Missense_Mutation	rs764709254	R989Q	0.32
HNSC	chr18	33739959	Missense_Mutation	novel	I852S	0.21
HNSC	chr18	33743014	Missense_Mutation	novel	D1056Y	0.2
HNSC	chr18	33646325	Silent	novel	E109E	0.27
HNSC	chr18	33746341	Missense_Mutation	novel	K2165Q	0.06
HNSC	chr18	33746631	3'UTR	rs756341246		0.24
HNSC	chr18	33743191	Missense_Mutation	novel	Q1115E	0.11
HNSC	chr18	33743197	Nonsense_Mutation	NA	R1117*	0.17
HNSC	chr18	33746078	Missense_Mutation	novel	S2077I	0.16
HNSC	chr18	33738722	Missense_Mutation	novel	E440K	0.21
HNSC	chr18	33744868	Missense_Mutation	rs770577167	E1674K	0.18
HNSC	chr18	33745355	Missense_Mutation	NA	G1836E	0.18
HNSC	chr18	33739007	Missense_Mutation	rs369560043	D535N	0.18
HNSC	chr18	33746292	Missense_Mutation	novel	Q2148H	0.65
HNSC	chr18	33745333	Missense_Mutation	novel	K1829Q	0.2
HNSC	chr18	33740075	Missense_Mutation	novel	D891N	0.17
HNSC	chr18	33644939	Silent	novel	N61N	0.17
HNSC	chr18	33745552	Missense_Mutation	novel	P1902A	0.06
HNSC	chr18	33744525	Silent	novel	L1559L	0.44
HNSC	chr18	33744526	Nonsense_Mutation	novel	R1560*	0.44
HNSC	chr18	33739015	Silent	novel	L537L	0.14
HNSC	chr18	33745490	Missense_Mutation	rs759812028	K1881R	0.14
HNSC	chr18	33739527	Missense_Mutation	NA	S708C	0.15
HNSC	chr18	33745424	Missense_Mutation	novel	C1859F	0.03
HNSC	chr18	33743027	Missense_Mutation	novel	R1060P	0.61
HNSC	chr18	33744742	Missense_Mutation	novel	E1632Q	0.21
HNSC	chr18	33746639	3'UTR	novel		0.25
HNSC	chr18	33744868	Nonsense_Mutation	novel	E1674*	0.33
HNSC	chr18	33740419	Frame_Shift_Del	novel	*E1005Dfs25**	0.22
HNSC	chr18	33734354	Nonsense_Mutation	novel	E341*	0.3
HNSC	chr18	33745335	Missense_Mutation	NA	K1829N	0.25
HNSC	chr18	33740021	Frame_Shift_Ins	novel	*V876Sfs13**	0.51
HNSC	chr18	33745466	Missense_Mutation	novel	P1873L	0.52
HNSC	chr18	33739255	Frame_Shift_Del	novel	*P618Qfs59**	0.52
HNSC	chr18	33743724	Nonsense_Mutation	novel	C1292*	0.56
HNSC	chr18	33646249	Missense_Mutation	novel	E84V	0.44
HNSC	chr18	33744151	Missense_Mutation	novel	E1435Q	0.17
HNSC	chr18	33739612	Silent	novel	L736L	0.06
HNSC	chr18	33739655	Missense_Mutation	novel	E751Q	0.26
HNSC	chr18	33745776	Silent	novel	S1976S	0.21
HNSC	chr18	33738566	Missense_Mutation	novel	G388W	0.31
HNSC	chr18	33743089	Missense_Mutation	novel	S1081G	0.11
HNSC	chr18	33739262	Missense_Mutation	novel	G620R	0.3
HNSC	chr18	33738575	Missense_Mutation	novel	G391C	0.1
KIRC	chr18	33732005	Missense_Mutation	NA	A306G	0.25
KIRC	chr18	33738836	Missense_Mutation	NA	E478K	0.14
KIRC	chr18	33744998	Missense_Mutation	NA	E1717A	0.25
KIRC	chr18	33740391	Missense_Mutation	NA	P996Q	0.28
KIRP	chr18	33683454	Silent	NA	G255G	0.27
KIRP	chr18	33745225	Missense_Mutation	novel	E1793Q	0.35
KIRP	chr18	33644938	Missense_Mutation	NA	N61S	0.11	HARE-HTH
KIRP	chr18	33746711	3'UTR	novel		0.27
LAML	chr18	33738967	Silent	novel	G521G	0.41
LAML	chr18	33734336	Missense_Mutation	rs765803411	R335W	0.82
LAML	chr18	33683538	Frame_Shift_Del	novel	*L284Cfs24**	0.1
LGG	chr18	33744868	Missense_Mutation	rs770577167	E1674K	0.54
LGG	chr18	33740096	Missense_Mutation	novel	P898S	0.24
LGG	chr18	33745585	Missense_Mutation	novel	V1913I	0.24
LGG	chr18	33743701	Missense_Mutation	NA	I1285V	0.2
LIHC	chr18	33743041	Missense_Mutation	novel	R1065G	0.17
LIHC	chr18	33739102	Missense_Mutation	NA	E566D	0.19
LIHC	chr18	33739791	Missense_Mutation	NA	N796I	0.28
LIHC	chr18	33734321	Missense_Mutation	NA	P330S	0.27
LIHC	chr18	33734321	Missense_Mutation	NA	P330S	0.04
LIHC	chr18	33740307	Missense_Mutation	novel	E968G	0.06
LIHC	chr18	33739976	Missense_Mutation	novel	T858A	0.44
LIHC	chr18	33740074	Silent	novel	T890T	0.42
LIHC	chr18	33743474	Missense_Mutation	novel	V1209E	0.35
LUAD	chr18	33743448	Silent	NA	V1200V	0.32
LUAD	chr18	33745234	Missense_Mutation	NA	V1796F	0.39
LUAD	chr18	33739276	Missense_Mutation	rs778966078	S624R	0.6
LUAD	chr18	33746593	Nonstop_Mutation	NA	2249Qext17	0.23
LUAD	chr18	33739875	Missense_Mutation	NA	P824R	0.53
LUAD	chr18	33743043	Silent	NA	R1065R	0.14
LUAD	chr18	33744723	Silent	NA	S1625S	0.39
LUAD	chr18	33739097	Missense_Mutation	novel	V565L	0.5
LUAD	chr18	33743717	Missense_Mutation	novel	T1290S	0.06
LUAD	chr18	33646304	Missense_Mutation	NA	L102F	0.11
LUAD	chr18	33745309	Nonsense_Mutation	NA	R1821*	0.39
LUAD	chr18	33739455	Missense_Mutation	NA	S684Y	0.35
LUAD	chr18	33738722	Missense_Mutation	novel	E440Q	0.08
LUAD	chr18	33739691	Missense_Mutation	novel	R763G	0.08
LUAD	chr18	33744392	Missense_Mutation	novel	A1515G	0.07
LUAD	chr18	33738535	Missense_Mutation	novel	N377K	0.12
LUAD	chr18	33745299	Silent	novel	P1817P	0.12
LUAD	chr18	33746378	Missense_Mutation	novel	I2177N	0.13
LUAD	chr18	33739207	Missense_Mutation	NA	Q601H	0.53
LUAD	chr18	33744257	Missense_Mutation	NA	P1470Q	0.44
LUAD	chr18	33734359	Missense_Mutation	novel	K342N	0.33
LUAD	chr18	33734360	Nonsense_Mutation	novel	E343*	0.33
LUAD	chr18	33743051	Missense_Mutation	NA	R1068L	0.39
LUAD	chr18	33745005	Silent	NA	A1719A	0.25
LUAD	chr18	33743933	Missense_Mutation	novel	P1362Q	0.17
LUAD	chr18	33738505	Missense_Mutation	NA	E367D	0.35
LUAD	chr18	33744887	Missense_Mutation	novel	R1680T	0.07
LUAD	chr18	33739344	Frame_Shift_Del	novel	*T647Kfs30**	0.4
LUAD	chr18	33744023	Missense_Mutation	novel	R1392I	0.18
LUAD	chr18	33738517	Silent	rs202108426	K371K	0.3
LUAD	chr18	33745244	Missense_Mutation	NA	P1799Q	0.39
LUAD	chr18	33740112	Missense_Mutation	novel	Q903L	0.14
LUAD	chr18	33739495	Missense_Mutation	NA	N697K	0.55
LUAD	chr18	33744220	Missense_Mutation	NA	G1458R	0.27
LUAD	chr18	33742927	Missense_Mutation	novel	S1027C	0.38
LUAD	chr18	33744391	Missense_Mutation	novel	A1515P	0.45
LUAD	chr18	33745669	Missense_Mutation	novel	P1941T	0.37
LUAD	chr18	33743178	Silent	NA	L1110L	0.25
LUAD	chr18	33739557	Missense_Mutation	novel	P718Q	0.16
LUAD	chr18	33744907	Missense_Mutation	novel	P1687T	0.26
LUAD	chr18	33744700	Missense_Mutation	NA	G1618R	0.5
LUAD	chr18	33734344	Silent	novel	R337R	0.1
LUAD	chr18	33744585	Silent	novel	F1579F	0.22
LUAD	chr18	33740217	Missense_Mutation	novel	H938L	0.31
LUAD	chr18	33739250	Missense_Mutation	NA	E616Q	0.24
LUAD	chr18	33744172	Missense_Mutation	novel	G1442R	0.38
LUAD	chr18	33744819	Silent	novel	P1657P	0.48
LUAD	chr18	33745247	Missense_Mutation	novel	P1800H	0.54
LUAD	chr18	33739949	Missense_Mutation	novel	P849T	0.31
LUAD	chr18	33743134	Missense_Mutation	novel	T1096A	0.16
LUAD	chr18	33743638	Missense_Mutation	NA	L1264V	0.2
LUAD	chr18	33740021	Missense_Mutation	novel	E873K	0.12
LUAD	chr18	33740128	Silent	novel	I908I	0.24
LUAD	chr18	33744807	Silent	novel	S1653S	0.16
LUAD	chr18	33739266	Missense_Mutation	novel	A621G	0.54
LUAD	chr18	33745549	Missense_Mutation	novel	L1901I	0.07
LUAD	chr18	33743264	Missense_Mutation	novel	P1139H	0.13
LUAD	chr18	33743043	Silent	NA	R1065R	0.53
LUAD	chr18	33743918	Missense_Mutation	NA	S1357Y	0.53
LUAD	chr18	33745483	Silent	NA	L1879L	0.15
LUAD	chr18	33739611	Missense_Mutation	NA	L736P	0.26
LUAD	chr18	33743895	Silent	novel	N1349N	0.34
LUAD	chr18	33744988	Missense_Mutation	NA	S1714R	0.22
LUAD	chr18	33743376	Silent	NA	R1176R	0.29
LUAD	chr18	33745142	Missense_Mutation	NA	P1765Q	0.31
LUAD	chr18	33746077	Missense_Mutation	NA	S2077C	0.13
LUAD	chr18	33745272	Silent	rs186394703	K1808K	0.16
LUAD	chr18	33743312	Missense_Mutation	novel	S1155W	0.18
LUAD	chr18	33734336	Silent	rs765803411	R335R	0.16
LUAD	chr18	33743534	Missense_Mutation	novel	M1229K	0.39
LUAD	chr18	33743049	Silent	NA	Q1067Q	0.1
LUAD	chr18	33743841	Missense_Mutation	NA	S1331R	0.35
LUAD	chr18	33743375	Missense_Mutation	novel	R1176L	0.22
LUAD	chr18	33744385	Missense_Mutation	novel	P1513T	0.28
LUAD	chr18	33744386	Missense_Mutation	novel	P1513H	0.3
LUAD	chr18	33744257	Missense_Mutation	NA	P1470Q	0.27
LUAD	chr18	33739937	Missense_Mutation	NA	E845K	0.16
LUAD	chr18	33743360	Missense_Mutation	NA	K1171M	0.1
LUAD	chr18	33746619	3'UTR	novel		0.3
LUAD	chr18	33745055	Nonsense_Mutation	NA	S1736*	0.51
LUAD	chr18	33745687	Silent	novel	L1947L	0.06
LUAD	chr18	33745438	Missense_Mutation	novel	G1864R	0.07
LUAD	chr18	33739901	Missense_Mutation	novel	L833M	0.61
LUAD	chr18	33742955	Missense_Mutation	rs776506817	R1036L	0.26
LUAD	chr18	33743472	Silent	NA	P1208P	0.17
LUAD	chr18	33744891	Missense_Mutation	novel	M1681I	0.21
LUAD	chr18	33744892	Missense_Mutation	novel	D1682Y	0.19
LUAD	chr18	33743997	Silent	NA	A1383A	0.12
LUAD	chr18	33743019	Silent	novel	I1057I	0.15
LUAD	chr18	33744078	Missense_Mutation	NA	H1410Q	0.22
LUAD	chr18	33683443	Nonsense_Mutation	NA	E252*	0.46
LUAD	chr18	33740280	Nonsense_Mutation	NA	S959*	0.17
LUAD	chr18	33746545	Missense_Mutation	novel	D2233H	0.14
LUAD	chr18	33746546	Missense_Mutation	novel	D2233V	0.14
LUAD	chr18	33744566	Missense_Mutation	novel	T1573N	0.25
LUAD	chr18	33744604	Missense_Mutation	NA	P1586A	0.85
LUAD	chr18	33744271	Missense_Mutation	novel	V1475F	0.26
LUAD	chr18	33743666	Missense_Mutation	rs769334860	T1273I	0.14
LUAD	chr18	33743921	Missense_Mutation	NA	V1358A	0.32
LUAD	chr18	33739131	Nonsense_Mutation	NA	S576*	0.32
LUAD	chr18	33744948	Silent	NA	S1700S	0.12
LUAD	chr18	33745557	Silent	novel	S1903S	0.11
LUAD	chr18	33646280	Silent	novel	L94L	0.44
LUAD	chr18	33740202	Missense_Mutation	novel	R933L	0.47
LUAD	chr18	33745210	Missense_Mutation	novel	G1788C	0.47
LUAD	chr18	33740019	Missense_Mutation	novel	T872K	0.27
LUAD	chr18	33743925	Silent	NA	L1359L	0.09
LUAD	chr18	33746131	Missense_Mutation	NA	E2095K	0.55
LUAD	chr18	33746487	Silent	rs201578514	C2213C	0.54
LUAD	chr18	33746489	Missense_Mutation	NA	S2214F	0.52
LUAD	chr18	33744515	Missense_Mutation	novel	C1556F	0.11
LUAD	chr18	33745234	Missense_Mutation	rs755015351	V1796I	0.32
LUAD	chr18	33743803	Missense_Mutation	rs755541299	D1319Y	0.35
LUAD	chr18	33670672	Splice_Site	novel	X160_splice	0.54
LUAD	chr18	33743267	Missense_Mutation	rs201152513	P1140Q	0.39
LUAD	chr18	33743674	Missense_Mutation	NA	A1276P	0.16
LUAD	chr18	33739757	Nonsense_Mutation	NA	E785*	0.11
LUSC	chr18	33746066	Missense_Mutation	rs769078252	T2073M	0.12
LUSC	chr18	33745134	Missense_Mutation	novel	K1762N	0.33
LUSC	chr18	33743508	Silent	NA	T1220T	0.37
LUSC	chr18	33734380	Missense_Mutation	NA	W349C	0.4
LUSC	chr18	33744471	Silent	NA	A1541A	0.22
LUSC	chr18	33739944	Missense_Mutation	novel	P847H	0.35
LUSC	chr18	33746434	Missense_Mutation	rs752151003	P2196A	0.37
LUSC	chr18	33734360	Missense_Mutation	novel	E343K	0.15
LUSC	chr18	33745440	Silent	NA	G1864G	0.25
LUSC	chr18	33743046	Silent	novel	A1066A	0.43
LUSC	chr18	33646250	Silent	NA	E84E	0.27
LUSC	chr18	33743229	Silent	novel	T1127T	0.26
LUSC	chr18	33743299	Missense_Mutation	NA	K1151E	0.23
LUSC	chr18	33738738	Missense_Mutation	NA	P445L	0.19
LUSC	chr18	33744277	Missense_Mutation	NA	H1477Y	0.16
LUSC	chr18	33746244	Frame_Shift_Del	novel	*P2133Lfs73**	0.08
LUSC	chr18	33738783	Missense_Mutation	NA	T460S	0.14
LUSC	chr18	33739223	Missense_Mutation	novel	C607S	0.13
LUSC	chr18	33738934	Missense_Mutation	novel	E510D	0.28
LUSC	chr18	33738818	Missense_Mutation	novel	T472A	0.25
LUSC	chr18	33745548	Silent	novel	L1900L	0.08
LUSC	chr18	33683515	Missense_Mutation	NA	P276T	0.33
LUSC	chr18	33744320	Missense_Mutation	NA	V1491A	0.13
LUSC	chr18	33740374	Missense_Mutation	novel	N990K	0.09
LUSC	chr18	33743235	Missense_Mutation	novel	L1129F	0.31
LUSC	chr18	33646262	Frame_Shift_Del	novel	*P89Qfs8**	0.26
LUSC	chr18	33646250	Missense_Mutation	NA	E84D	0.35
LUSC	chr18	33746434	Missense_Mutation	novel	P2196S	0.25
LUSC	chr18	33738939	Missense_Mutation	novel	L512S	0.29
LUSC	chr18	33743753	Missense_Mutation	NA	S1302I	0.39
LUSC	chr18	33744077	Missense_Mutation	novel	H1410L	0.32
LUSC	chr18	33734370	Missense_Mutation	rs764330971	T346I	0.44
LUSC	chr18	33738803	Missense_Mutation	novel	D467Y	0.16
LUSC	chr18	33743907	Silent	NA	L1353L	0.73
LUSC	chr18	33743286	Silent	NA	S1146S	0.18
LUSC	chr18	33746650	3'UTR	novel		0.23
LUSC	chr18	33740041	Silent	NA	S879S	0.09
LUSC	chr18	33745712	Missense_Mutation	novel	P1955Q	0.14
LUSC	chr18	33744502	Silent	NA	L1552L	0.2
LUSC	chr18	33745327	Missense_Mutation	novel	P1827S	0.06
LUSC	chr18	33745665	Missense_Mutation	novel	R1939S	0.29
LUSC	chr18	33745364	Missense_Mutation	rs765369686	T1839I	0.05
LUSC	chr18	33738662	Missense_Mutation	novel	A420T	0.12
LUSC	chr18	33743241	Silent	novel	P1131P	0.24
LUSC	chr18	33745585	Missense_Mutation	novel	V1913L	0.19
LUSC	chr18	33743515	Nonsense_Mutation	novel	E1223*	0.1
LUSC	chr18	33743125	Missense_Mutation	novel	G1093S	0.11
LUSC	chr18	33738525	Missense_Mutation	novel	T374S	0.41
LUSC	chr18	33743925	Silent	NA	L1359L	0.17
LUSC	chr18	33739765	Silent	novel	S787S	0.34
LUSC	chr18	33743005	Missense_Mutation	novel	T1053A	0.24
MESO	chr18	33738849	Missense_Mutation	novel	S482I	0.12
MESO	chr18	33683501	Missense_Mutation	rs772111853	T271M	0.73
OV	chr18	33744587	Frame_Shift_Ins	novel	*E1581Hfs38**	0.44
OV	chr18	33734360	Nonsense_Mutation	novel	E343*	0.17
OV	chr18	33661708	Missense_Mutation	NA	Q150K	0.06
OV	chr18	33739092	Missense_Mutation	rs753638332	T563I	0.32
OV	chr18	33743706	Missense_Mutation	NA	Q1286H	0.07
OV	chr18	33743154	Missense_Mutation	NA	I1102M	0.11
OV	chr18	33732059	Missense_Mutation	novel	A324E	0.09
OV	chr18	33743005	Missense_Mutation	NA	T1053S	0.31
OV	chr18	33738491	Missense_Mutation	NA	G363S	0.68
OV	chr18	33746095	Missense_Mutation	novel	P2083S	0.08
OV	chr18	33746084	Missense_Mutation	novel	I2079R	0.06
OV	chr18	33740343	Missense_Mutation	novel	A980V	0.15
OV	chr18	33746617	3'UTR	novel		0.47
OV	chr18	33746710	3'UTR	novel		0.08
OV	chr18	33740022	Frame_Shift_Del	NA	*V876Cfs59**	0.4
OV	chr18	33743063	Missense_Mutation	novel	A1072V	0.35
OV	chr18	33743064	Silent	rs769685194	A1072A	0.33
OV	chr18	33646276	Missense_Mutation	rs770800472	T93M	0.15
OV	chr18	33740106	Frame_Shift_Ins	novel	*K901Nfs40**	0.07
PAAD	chr18	33744354	Silent	novel	G1502G	0.19
PAAD	chr18	33745063	Missense_Mutation	rs376309030	R1739C	0.17
PAAD	chr18	33746350	Missense_Mutation	novel	A2168T	0.19
PRAD	chr18	33743345	Missense_Mutation	novel	R1166K	0.41
READ	chr18	33746193	Silent	rs763915321	F2115F	0.39
READ	chr18	33734402	Missense_Mutation	novel	F357I	0.09
READ	chr18	33743140	Missense_Mutation	NA	T1098P	1
READ	chr18	33743819	Missense_Mutation	NA	L1324Q	0.25
READ	chr18	33745101	Silent	NA	T1751T	0.54
READ	chr18	33743700	Silent	novel	T1284T	0.16
READ	chr18	33738817	Missense_Mutation	NA	K471N	0.42
READ	chr18	33739058	Missense_Mutation	NA	H552N	0.3
READ	chr18	33739814	Missense_Mutation	NA	L804M	0.38
READ	chr18	33745316	Missense_Mutation	rs201071954	R1823Q	0.47
READ	chr18	33746253	Silent	NA	T2135T	0.32
READ	chr18	33661622	Missense_Mutation	rs753959478	S121L	0.16
READ	chr18	33732021	Missense_Mutation	NA	F311L	0.24
READ	chr18	33738907	Silent	NA	S501S	0.36
SARC	chr18	33578676	Silent	novel	A15A	0.19
SARC	chr18	33744465	Silent	novel	F1539F	0.27
SARC	chr18	33740432	Missense_Mutation	novel	P1010A	0.24
SARC	chr18	33743312	Missense_Mutation	rs377619533	S1155L	0.64
SARC	chr18	33740272	Silent	novel	S956S	0.06
SARC	chr18	33671812	Missense_Mutation	rs267605172	P221S	0.24
SKCM	chr18	33742898	Missense_Mutation	NA	S1017F	0.43
SKCM	chr18	33738919	Missense_Mutation	novel	M505I	0.17
SKCM	chr18	33743956	Missense_Mutation	NA	P1370S	0.3
SKCM	chr18	33738812	Missense_Mutation	NA	H470Y	0.56
SKCM	chr18	33743379	Silent	NA	E1177E	0.39
SKCM	chr18	33740394	Missense_Mutation	NA	P997L	0.42
SKCM	chr18	33739785	Missense_Mutation	novel	G794E	0.36
SKCM	chr18	33745021	Missense_Mutation	rs201072457	D1725N	0.28
SKCM	chr18	33731972	Missense_Mutation	NA	G295E	0.25
SKCM	chr18	33746016	Missense_Mutation	NA	Q2056H	0.53
SKCM	chr18	33671846	Missense_Mutation	NA	R232Q	0.28
SKCM	chr18	33743585	Missense_Mutation	rs552703360	S1246L	0.16
SKCM	chr18	33743865	Silent	rs767294351	T1339T	0.23
SKCM	chr18	33744422	Missense_Mutation	NA	P1525R	0.13
SKCM	chr18	33671793	Missense_Mutation	novel	M214I	0.32
SKCM	chr18	33739154	Missense_Mutation	NA	P584S	0.41
SKCM	chr18	33744317	Missense_Mutation	novel	S1490Y	0.49
SKCM	chr18	33738916	Missense_Mutation	NA	M504I	0.35
SKCM	chr18	33744929	Missense_Mutation	rs377243058	P1694L	0.25
SKCM	chr18	33746554	Missense_Mutation	NA	G2236S	0.62
SKCM	chr18	33745021	Missense_Mutation	rs201072457	D1725N	0.19
SKCM	chr18	33738561	Missense_Mutation	NA	S386L	0.17
SKCM	chr18	33739082	Missense_Mutation	rs745776273	E560K	0.19
SKCM	chr18	33744939	Silent	novel	E1697E	0.2
SKCM	chr18	33745063	Missense_Mutation	rs376309030	R1739C	0.09
SKCM	chr18	33744690	Missense_Mutation	novel	M1614I	0.27
SKCM	chr18	33744248	Missense_Mutation	rs754700314	R1467Q	0.37
SKCM	chr18	33743956	Missense_Mutation	NA	P1370S	0.37
SKCM	chr18	33740201	Missense_Mutation	rs376307971	R933W	0.41
SKCM	chr18	33738890	Missense_Mutation	NA	E496K	0.43
SKCM	chr18	33738651	Missense_Mutation	NA	P416L	0.11
SKCM	chr18	33746557	Missense_Mutation	rs371155785	P2237S	0.85
SKCM	chr18	33743008	Missense_Mutation	novel	L1054F	0.45
SKCM	chr18	33739204	Silent	NA	E600E	0.26
SKCM	chr18	33738505	Silent	NA	E367E	0.29
SKCM	chr18	33744200	Missense_Mutation	NA	G1451E	0.38
SKCM	chr18	33745586	Missense_Mutation	NA	V1913A	0.37
SKCM	chr18	33744858	Silent	novel	S1670S	0.05
SKCM	chr18	33744943	Missense_Mutation	rs376961486	A1699T	0.49
SKCM	chr18	33738761	Missense_Mutation	NA	E453K	0.29
SKCM	chr18	33734360	Missense_Mutation	novel	E343K	0.26
SKCM	chr18	33739779	Missense_Mutation	rs555695471	P792L	0.23
SKCM	chr18	33743710	Missense_Mutation	novel	T1288A	0.28
SKCM	chr18	33743957	Missense_Mutation	novel	P1370L	0.35
SKCM	chr18	33744687	Silent	novel	G1613G	0.3
SKCM	chr18	33661622	Missense_Mutation	rs753959478	S121L	0.2
SKCM	chr18	33738651	Missense_Mutation	NA	P416L	0.3
SKCM	chr18	33740289	Missense_Mutation	NA	S962L	0.35
SKCM	chr18	33744972	Missense_Mutation	NA	M1708I	0.29
SKCM	chr18	33745195	Nonsense_Mutation	NA	Q1783*	0.29
SKCM	chr18	33745582	Missense_Mutation	NA	H1912Y	0.19
SKCM	chr18	33744080	Missense_Mutation	rs767761454	P1411L	0.52
SKCM	chr18	33743692	Frame_Shift_Del	novel	L1282*	0.3
SKCM	chr18	33743956	Missense_Mutation	NA	P1370S	0.33
SKCM	chr18	33745354	Missense_Mutation	NA	G1836R	0.1
SKCM	chr18	33734391	Missense_Mutation	NA	F353C	0.18
SKCM	chr18	33740038	Silent	NA	P878P	0.48
SKCM	chr18	33743136	Silent	rs543703623	T1096T	1
SKCM	chr18	33743371	Missense_Mutation	NA	L1175F	0.5
SKCM	chr18	33743239	Missense_Mutation	rs189035129	P1131S	0.15
SKCM	chr18	33745415	Missense_Mutation	NA	G1856E	0.06
SKCM	chr18	33734384	Missense_Mutation	novel	E351K	0.55
SKCM	chr18	33740326	Silent	NA	I974I	0.36
SKCM	chr18	33743486	Missense_Mutation	novel	S1213F	0.23
SKCM	chr18	33745385	Missense_Mutation	NA	G1846E	0.11
SKCM	chr18	33745924	Missense_Mutation	NA	P2026S	0.5
SKCM	chr18	33746375	Missense_Mutation	NA	G2176E	0.29
SKCM	chr18	33739277	Silent	NA	L625L	0.17
SKCM	chr18	33739320	Missense_Mutation	novel	S639L	0.29
SKCM	chr18	33683559	Silent	NA	V290V	0.19
SKCM	chr18	33738761	Missense_Mutation	NA	E453K	0.36
SKCM	chr18	33744365	Missense_Mutation	NA	R1506K	0.19
SKCM	chr18	33743136	Silent	rs543703623	T1096T	0.29
SKCM	chr18	33731969	Missense_Mutation	novel	M294K	0.34
SKCM	chr18	33646338	Nonsense_Mutation	novel	G114delinsDIYMIYL*	0.18
SKCM	chr18	33740201	Missense_Mutation	rs376307971	R933W	0.52
SKCM	chr18	33744084	Silent	rs756320994	T1412T	0.24
SKCM	chr18	33743937	Missense_Mutation	NA	M1363I	0.24
SKCM	chr18	33738917	Missense_Mutation	novel	M505L	0.57
SKCM	chr18	33745530	Silent	NA	V1894V	0.45
SKCM	chr18	33746558	Missense_Mutation	NA	P2237L	0.71
SKCM	chr18	33746684	3'UTR	novel		0.25
SKCM	chr18	33671747	Missense_Mutation	NA	G199E	0.48
SKCM	chr18	33740432	Missense_Mutation	NA	P1010S	0.24
SKCM	chr18	33732064	Missense_Mutation	NA	G326R	0.06
SKCM	chr18	33739478	Missense_Mutation	novel	A692T	0.08
SKCM	chr18	33739956	Missense_Mutation	NA	S851L	0.18
SKCM	chr18	33745703	Missense_Mutation	NA	S1952F	0.1
SKCM	chr18	33739797	Missense_Mutation	NA	T798N	0.34
SKCM	chr18	33745328	Missense_Mutation	NA	P1827L	0.35
SKCM	chr18	33742940	Missense_Mutation	rs375247575	S1031F	0.39
SKCM	chr18	33738823	Silent	novel	I473I	0.1
SKCM	chr18	33739155	Missense_Mutation	novel	P584L	0.24
SKCM	chr18	33743956	Missense_Mutation	NA	P1370S	0.35
SKCM	chr18	33743410	Missense_Mutation	NA	P1188S	0.23
SKCM	chr18	33743799	Silent	NA	S1317S	0.36
SKCM	chr18	33738761	Missense_Mutation	NA	E453K	0.2
SKCM	chr18	33743803	Missense_Mutation	NA	D1319N	0.31
SKCM	chr18	33743422	Missense_Mutation	NA	P1192S	0.38
SKCM	chr18	33743806	Missense_Mutation	NA	D1320N	0.41
SKCM	chr18	33740137	Silent	NA	V911V	0.24
SKCM	chr18	33744700	Missense_Mutation	NA	G1618R	0.46
SKCM	chr18	33739875	Missense_Mutation	rs764053964	P824L	0.28
SKCM	chr18	33732005	Missense_Mutation	NA	A306V	0.43
SKCM	chr18	33746176	Missense_Mutation	novel	E2110K	0.3
SKCM	chr18	33743956	Missense_Mutation	NA	P1370S	0.37
SKCM	chr18	33740242	Silent	NA	S946S	0.33
SKCM	chr18	33745316	Missense_Mutation	rs201071954	R1823Q	0.1
SKCM	chr18	33746153	Missense_Mutation	NA	S2102F	0.34
SKCM	chr18	33739602	Missense_Mutation	NA	S733F	0.45
SKCM	chr18	33743986	Missense_Mutation	NA	E1380K	0.45
SKCM	chr18	33646351	Missense_Mutation	NA	G118E	0.08
SKCM	chr18	33743010	Silent	rs369994676	L1054L	0.09
SKCM	chr18	33745514	Missense_Mutation	NA	V1889A	0.2
SKCM	chr18	33740048	Missense_Mutation	NA	E882K	0.16
SKCM	chr18	33743508	Silent	NA	T1220T	0.27
SKCM	chr18	33744821	Missense_Mutation	NA	R1658K	0.15
SKCM	chr18	33743929	Missense_Mutation	NA	P1361S	0.43
SKCM	chr18	33745183	Missense_Mutation	NA	P1779S	0.56
SKCM	chr18	33743556	Silent	NA	V1236V	0.3
SKCM	chr18	33743929	Missense_Mutation	NA	P1361S	0.13
SKCM	chr18	33746362	Missense_Mutation	NA	E2172K	0.7
SKCM	chr18	33731981	Missense_Mutation	NA	G298E	0.29
SKCM	chr18	33744822	Silent	NA	R1658R	0.4
SKCM	chr18	33739796	Missense_Mutation	novel	T798S	0.37
SKCM	chr18	33739797	Missense_Mutation	novel	T798I	0.34
SKCM	chr18	33738776	Missense_Mutation	NA	V458I	0.16
SKCM	chr18	33644910	Missense_Mutation	novel	A52T	0.5	HARE-HTH
SKCM	chr18	33743956	Missense_Mutation	NA	P1370S	0.29
SKCM	chr18	33743501	Missense_Mutation	rs780764559	S1218L	0.2
SKCM	chr18	33744220	Missense_Mutation	NA	G1458R	0.26
SKCM	chr18	33744781	Missense_Mutation	NA	E1645K	0.22
SKCM	chr18	33743956	Missense_Mutation	NA	P1370S	0.27
SKCM	chr18	33745156	Missense_Mutation	NA	G1770R	0.41
SKCM	chr18	33743783	Missense_Mutation	novel	S1312F	0.36
SKCM	chr18	33743784	Silent	novel	S1312S	0.36
SKCM	chr18	33742898	Missense_Mutation	NA	S1017F	0.69
SKCM	chr18	33746303	Missense_Mutation	novel	G2152E	0.85
SKCM	chr18	33739160	Missense_Mutation	NA	E586K	0.39
SKCM	chr18	33739262	Missense_Mutation	novel	G620R	0.3
SKCM	chr18	33739263	Missense_Mutation	NA	G620E	0.3
SKCM	chr18	33745105	Silent	NA	L1753L	0.52
SKCM	chr18	33745476	Silent	NA	Q1876Q	0.45
SKCM	chr18	33739154	Missense_Mutation	NA	P584S	0.53
SKCM	chr18	33745766	Missense_Mutation	NA	G1973E	0.43
SKCM	chr18	33746575	Missense_Mutation	novel	A2243S	0.37
SKCM	chr18	33746576	Missense_Mutation	novel	A2243V	0.37
SKCM	chr18	33744005	Missense_Mutation	NA	S1386F	0.52
SKCM	chr18	33744891	Missense_Mutation	NA	M1681I	0.12
SKCM	chr18	33740053	Missense_Mutation	NA	L883F	0.39
SKCM	chr18	33745355	Missense_Mutation	NA	G1836E	0.63
SKCM	chr18	33745243	Missense_Mutation	NA	P1799S	0.22
SKCM	chr18	33661707	Silent	novel	F149F	0.42
SKCM	chr18	33743154	Silent	novel	I1102I	0.28
SKCM	chr18	33746133	Silent	rs769416388	E2095E	0.18
SKCM	chr18	33746149	Missense_Mutation	NA	V2101F	0.35
SKCM	chr18	33671866	Missense_Mutation	novel	G239R	0.32
SKCM	chr18	33738761	Missense_Mutation	NA	E453K	0.6
SKCM	chr18	33746376	Silent	novel	G2176G	0.41
SKCM	chr18	33743019	Silent	novel	I1057I	0.39
SKCM	chr18	33743138	Missense_Mutation	novel	R1097K	0.4
SKCM	chr18	33745337	Missense_Mutation	novel	R1830K	0.3
SKCM	chr18	33746626	3'UTR	novel		0.35
SKCM	chr18	33740187	Missense_Mutation	NA	G928E	0.23
SKCM	chr18	33739554	Missense_Mutation	NA	S717L	0.7
SKCM	chr18	33745146	Silent	rs780762296	Q1766Q	0.2
SKCM	chr18	33743010	Silent	rs369994676	L1054L	0.42
SKCM	chr18	33745983	Silent	NA	L2045L	0.17
SKCM	chr18	33738725	Missense_Mutation	rs769342199	D441N	0.42
SKCM	chr18	33744384	Silent	rs538610692	Q1512Q	0.31
SKCM	chr18	33646351	Missense_Mutation	NA	G118E	0.24
SKCM	chr18	33739829	Missense_Mutation	rs749484741	E809K	0.55
SKCM	chr18	33745108	Silent	NA	L1754L	0.41
SKCM	chr18	33743704	Nonsense_Mutation	NA	Q1286*	0.18
SKCM	chr18	33732016	Missense_Mutation	NA	E310K	0.56
SKCM	chr18	33743956	Missense_Mutation	NA	P1370S	0.47
SKCM	chr18	33744451	Missense_Mutation	NA	H1535Y	0.47
SKCM	chr18	33743312	Missense_Mutation	rs377619533	S1155L	0.37
SKCM	chr18	33744439	Missense_Mutation	novel	E1531K	0.36
SKCM	chr18	33746398	Missense_Mutation	novel	P2184S	0.41
SKCM	chr18	33732016	Missense_Mutation	NA	E310K	0.23
SKCM	chr18	33739671	Missense_Mutation	novel	S756F	0.34
SKCM	chr18	33743956	Missense_Mutation	NA	P1370S	0.29
SKCM	chr18	33744986	Missense_Mutation	novel	S1713L	0.32
SKCM	chr18	33744031	Missense_Mutation	rs756275562	L1395F	0.28
SKCM	chr18	33744981	Silent	novel	S1711S	0.23
SKCM	chr18	33745286	Missense_Mutation	NA	G1813E	0.16
SKCM	chr18	33744238	Missense_Mutation	novel	A1464T	0.39
SKCM	chr18	33744925	Missense_Mutation	novel	P1693S	0.4
SKCM	chr18	33744926	Missense_Mutation	novel	P1693L	0.39
SKCM	chr18	33745416	Silent	rs750295443	G1856G	0.34
SKCM	chr18	33743956	Missense_Mutation	NA	P1370S	0.35
SKCM	chr18	33743806	Missense_Mutation	NA	D1320N	0.42
SKCM	chr18	33740187	Missense_Mutation	NA	G928E	0.39
SKCM	chr18	33738775	Silent	NA	E457E	0.61
SKCM	chr18	33740048	Missense_Mutation	NA	E882K	0.62
SKCM	chr18	33745520	Missense_Mutation	NA	S1891N	0.65
SKCM	chr18	33744868	Missense_Mutation	rs770577167	E1674K	0.36
SKCM	chr18	33740197	Silent	novel	Q931Q	0.31
SKCM	chr18	33745029	Silent	novel	L1727L	0.33
STAD	chr18	33743602	Missense_Mutation	NA	H1252N	0.38
STAD	chr18	33743530	Missense_Mutation	rs749701695	P1228S	0.09
STAD	chr18	33745037	Missense_Mutation	NA	V1730D	0.24
STAD	chr18	33746193	Silent	rs763915321	F2115F	0.17
STAD	chr18	33683480	Missense_Mutation	NA	R264K	0.29
STAD	chr18	33746103	Frame_Shift_Del	novel	*F2086Lfs5**	0.13
STAD	chr18	33746494	Missense_Mutation	NA	R2216W	0.18
STAD	chr18	33746475	Silent	novel	L2209L	0.27
STAD	chr18	33740022	Frame_Shift_Del	NA	*V876Cfs59**	0.2
STAD	chr18	33743105	Missense_Mutation	NA	A1086V	0.3
STAD	chr18	33740022	Frame_Shift_Del	NA	*V876Cfs59**	0.32
STAD	chr18	33745908	Silent	rs369151165	P2020P	0.39
STAD	chr18	33743694	Frame_Shift_Del	novel	*T1284Pfs10**	0.18
STAD	chr18	33740022	Frame_Shift_Del	NA	*V876Cfs59**	0.33
STAD	chr18	33745272	Missense_Mutation	NA	K1808N	0.25
STAD	chr18	33743665	Missense_Mutation	NA	T1273A	0.23
STAD	chr18	33745614	Silent	rs752156735	D1922D	0.39
STAD	chr18	33743552	Missense_Mutation	NA	S1235Y	0.36
STAD	chr18	33745333	Missense_Mutation	novel	K1829Q	0.31
STAD	chr18	33739715	Missense_Mutation	NA	S771T	0.15
STAD	chr18	33743550	Missense_Mutation	NA	N1234K	0.08
STAD	chr18	33740022	Frame_Shift_Del	NA	*V876Cfs59**	0.26
STAD	chr18	33743124	Missense_Mutation	NA	E1092D	0.18
STAD	chr18	33744742	Missense_Mutation	NA	E1632K	0.27
STAD	chr18	33740022	Frame_Shift_Del	NA	*V876Cfs59**	0.25
STAD	chr18	33746066	Missense_Mutation	rs769078252	T2073M	0.07
STAD	chr18	33743011	Missense_Mutation	NA	A1055T	0.19
STAD	chr18	33743140	Missense_Mutation	NA	T1098P	0.13
STAD	chr18	33739827	Missense_Mutation	NA	P808L	0.51
STAD	chr18	33746076	Silent	rs760737437	C2076C	0.54
STAD	chr18	33746195	Missense_Mutation	rs757112357	A2116V	0.25
STAD	chr18	33646322	Silent	rs374843800	A108A	0.05
STAD	chr18	33738806	Frame_Shift_Ins	novel	*N469Kfs3**	0.29
STAD	chr18	33744829	Missense_Mutation	NA	V1661I	0.19
STAD	chr18	33739876	Silent	rs368115045	P824P	0.12
STAD	chr18	33740022	Frame_Shift_Del	NA	*V876Cfs59**	0.35
STAD	chr18	33742974	Silent	NA	S1042S	0.26
STAD	chr18	33739568	Missense_Mutation	novel	L722V	0.1
STAD	chr18	33739018	Missense_Mutation	NA	E538D	0.11
STAD	chr18	33739572	Missense_Mutation	NA	P723H	0.32
STAD	chr18	33671791	Missense_Mutation	NA	M214V	0.22
STAD	chr18	33744957	Missense_Mutation	NA	Q1703H	0.19
STAD	chr18	33745863	Silent	NA	T2005T	0.18
STAD	chr18	33745958	Missense_Mutation	NA	P2037L	0.47
STAD	chr18	33739432	Silent	NA	L676L	0.07
STAD	chr18	33683487	Silent	NA	L266L	0.27
TGCT	chr18	33744053	Missense_Mutation	rs763759484	A1402V	0.44
UCEC	chr18	33738558	Missense_Mutation	NA	S385Y	0.34
UCEC	chr18	33739810	Missense_Mutation	NA	K802N	0.26
UCEC	chr18	33739989	Missense_Mutation	NA	K862T	0.37
UCEC	chr18	33734400	Missense_Mutation	NA	R356M	0.15
UCEC	chr18	33739754	Missense_Mutation	NA	D784Y	0.48
UCEC	chr18	33739024	Silent	novel	C540C	0.45
UCEC	chr18	33738698	Missense_Mutation	novel	D432Y	0.09
UCEC	chr18	33739577	Missense_Mutation	NA	T725A	0.34
UCEC	chr18	33743662	Missense_Mutation	NA	T1272A	0.13
UCEC	chr18	33745967	Missense_Mutation	rs765788846	P2040L	0.41
UCEC	chr18	33607612	Missense_Mutation	novel	N25D	0.31	HARE-HTH
UCEC	chr18	33670749	Missense_Mutation	novel	T185I	0.29
UCEC	chr18	33739638	Missense_Mutation	novel	S745N	0.2
UCEC	chr18	33742890	Splice_Region	novel	I1014I	0.53
UCEC	chr18	33743591	Missense_Mutation	novel	A1248V	0.58
UCEC	chr18	33744636	Silent	novel	T1596T	0.31
UCEC	chr18	33644896	Missense_Mutation	NA	G47V	0.31	HARE-HTH
UCEC	chr18	33739913	Missense_Mutation	NA	T837A	0.18
UCEC	chr18	33746341	Missense_Mutation	novel	K2165E	0.08
UCEC	chr18	33578638	Missense_Mutation	novel	D3Y	0.21
UCEC	chr18	33746682	3'UTR	novel		0.5
UCEC	chr18	33744929	Missense_Mutation	rs377243058	P1694L	0.73
UCEC	chr18	33745322	Missense_Mutation	novel	N1825I	0.36
UCEC	chr18	33745439	Missense_Mutation	novel	G1864D	0.2
UCEC	chr18	33646283	Silent	novel	D95D	0.45
UCEC	chr18	33739697	Missense_Mutation	novel	A765T	0.44
UCEC	chr18	33734354	Missense_Mutation	NA	E341Q	0.38
UCEC	chr18	33744966	Silent	NA	Q1706Q	0.34
UCEC	chr18	33738502	Silent	rs545827056	R366R	0.11
UCEC	chr18	33743049	Silent	NA	Q1067Q	0.14
UCEC	chr18	33743837	Missense_Mutation	NA	A1330D	0.28
UCEC	chr18	33743737	Missense_Mutation	NA	P1297T	0.41
UCEC	chr18	33671849	Frame_Shift_Ins	novel	*S236Vfs12**	0.52
UCEC	chr18	33739110	Missense_Mutation	NA	T569I	0.13
UCEC	chr18	33745242	Missense_Mutation	NA	I1798M	0.18
UCEC	chr18	33738799	Silent	NA	C465C	0.23
UCEC	chr18	33739122	Missense_Mutation	novel	K573R	0.19
UCEC	chr18	33740067	Missense_Mutation	novel	E888V	0.16
UCEC	chr18	33740244	Missense_Mutation	novel	K947M	0.17
UCEC	chr18	33734337	Missense_Mutation	NA	R335Q	0.38
UCEC	chr18	33738923	Missense_Mutation	NA	D507Y	0.55
UCEC	chr18	33744931	Missense_Mutation	NA	A1695T	0.13
UCEC	chr18	33670693	Frame_Shift_Ins	novel	*R167Ifs9**	0.04
UCEC	chr18	33607678	Splice_Site	novel	X46_splice	0.31
UCEC	chr18	33661729	Missense_Mutation	NA	L157I	0.09
UCEC	chr18	33671759	Missense_Mutation	novel	K203T	0.3
UCEC	chr18	33734312	Nonsense_Mutation	novel	E327*	0.15
UCEC	chr18	33739006	Silent	rs376598388	I534I	0.56
UCEC	chr18	33739602	Missense_Mutation	novel	S733Y	0.45
UCEC	chr18	33745572	Missense_Mutation	rs746172646	Q1908H	0.12
UCEC	chr18	33746442	Silent	novel	Q2198Q	0.43
UCEC	chr18	33734345	Missense_Mutation	novel	Q338E	0.19
UCEC	chr18	33738989	Nonsense_Mutation	NA	E529*	0.34
UCEC	chr18	33739207	Silent	novel	Q601Q	0.2
UCEC	chr18	33739398	Missense_Mutation	novel	R665I	0.32
UCEC	chr18	33740201	Missense_Mutation	rs376307971	R933W	0.5
UCEC	chr18	33744248	Missense_Mutation	rs754700314	R1467Q	0.3
UCEC	chr18	33744957	Missense_Mutation	NA	Q1703H	0.21
UCEC	chr18	33745631	Missense_Mutation	novel	R1928I	0.41
UCEC	chr18	33734336	Missense_Mutation	rs765803411	R335W	0.27
UCEC	chr18	33683541	Silent	novel	L284L	0.35
UCEC	chr18	33732041	Missense_Mutation	novel	G318E	0.26
UCEC	chr18	33744420	Silent	novel	R1524R	0.23
UCEC	chr18	33744768	Missense_Mutation	novel	K1640N	0.32
UCEC	chr18	33746632	3'UTR	rs780395903		0.23
UCEC	chr18	33646286	Silent	novel	L96L	0.17
UCEC	chr18	33670783	Silent	rs755997232	S196S	0.44
UCEC	chr18	33740239	Silent	novel	P945P	0.45
UCEC	chr18	33743951	Missense_Mutation	NA	R1368K	0.4
UCEC	chr18	33746350	Missense_Mutation	novel	A2168T	0.29
UCEC	chr18	33745951	Frame_Shift_Del	NA	*P2037Hfs43**	0.38
UCEC	chr18	33744886	Frame_Shift_Del	novel	*R1680Sfs3**	0.28
UCEC	chr18	33742996	Missense_Mutation	novel	G1050R	0.38
UCEC	chr18	33743850	Silent	novel	V1334V	0.38
UCEC	chr18	33744887	Missense_Mutation	novel	R1680I	0.47
UCEC	chr18	33734401	Silent	novel	R356R	0.21
UCEC	chr18	33743490	Missense_Mutation	novel	E1214D	0.21
UCEC	chr18	33744659	Missense_Mutation	novel	S1604I	0.43
UCEC	chr18	33745650	Missense_Mutation	novel	M1934I	0.33
UCEC	chr18	33746289	Silent	rs755857123	Q2147Q	0.33
UCEC	chr18	33661682	Missense_Mutation	novel	V141A	0.25
UCEC	chr18	33740322	Missense_Mutation	novel	G973E	0.36
UCEC	chr18	33646341	Nonsense_Mutation	novel	E115*	0.13
UCEC	chr18	33738912	Missense_Mutation	rs747353588	V503G	0.28
UCEC	chr18	33739733	Nonsense_Mutation	novel	E777*	0.24
UCEC	chr18	33743014	Missense_Mutation	novel	D1056Y	0.32
UCEC	chr18	33744542	Missense_Mutation	novel	V1565A	0.4
UCEC	chr18	33683461	Missense_Mutation	novel	L258I	0.37
UCEC	chr18	33739050	Missense_Mutation	NA	S549Y	0.42
UCEC	chr18	33739810	Missense_Mutation	NA	K802N	0.42
UCEC	chr18	33744534	Frame_Shift_Ins	novel	*P1563Sfs6**	0.1
UCEC	chr18	33744535	Frame_Shift_Ins	novel	*P1563Lfs8**	0.09
UCEC	chr18	33746487	Nonsense_Mutation	novel	C2213*	0.06
UCEC	chr18	33740022	Frame_Shift_Del	NA	*V876Cfs59**	0.17
UCEC	chr18	33739496	Missense_Mutation	novel	L698V	0.43
UCEC	chr18	33739848	Missense_Mutation	novel	S815Y	0.57
UCEC	chr18	33743280	Silent	novel	V1144V	0.42
UCEC	chr18	33745116	Silent	novel	G1756G	0.43
UCEC	chr18	33746438	Missense_Mutation	novel	V2197A	0.31
UCEC	chr18	33743236	Missense_Mutation	novel	P1130S	0.3
UCEC	chr18	33746588	Missense_Mutation	novel	V2247A	0.37
UCEC	chr18	33743011	Missense_Mutation	NA	A1055T	0.49
UCEC	chr18	33644944	Missense_Mutation	novel	R63Q	0.43	HARE-HTH
UCEC	chr18	33661709	Missense_Mutation	novel	Q150P	0.35
UCEC	chr18	33671788	Nonsense_Mutation	novel	E213*	0.33
UCEC	chr18	33739115	Missense_Mutation	novel	K571E	0.59
UCEC	chr18	33739829	Missense_Mutation	rs749484741	E809K	0.17
UCEC	chr18	33744984	Silent	novel	T1712T	0.24
UCEC	chr18	33740195	Nonsense_Mutation	novel	Q931*	0.3
UCEC	chr18	33740005	Frame_Shift_Del	novel	*V868Cfs66**	0.03
UCEC	chr18	33683461	Missense_Mutation	novel	L258I	0.39
UCEC	chr18	33738696	Missense_Mutation	novel	K431T	0.26
UCEC	chr18	33739006	Silent	rs376598388	I534I	0.32
UCEC	chr18	33739321	Silent	rs773825613	S639S	0.33
UCEC	chr18	33743897	Missense_Mutation	novel	L1350S	0.24
UCEC	chr18	33744476	Missense_Mutation	rs781715733	S1543L	0.38
UCEC	chr18	33745183	Missense_Mutation	NA	P1779S	0.25
UCEC	chr18	33746214	Missense_Mutation	rs779258887	F2122L	0.39
UCEC	chr18	33746470	Nonsense_Mutation	novel	E2208*	0.42
UCEC	chr18	33734336	Missense_Mutation	rs765803411	R335W	0.39
UCEC	chr18	33742913	Missense_Mutation	novel	P1022H	0.33
UCEC	chr18	33743741	Missense_Mutation	novel	K1298T	0.5
UCEC	chr18	33743905	Missense_Mutation	novel	L1353I	0.5
UCEC	chr18	33744065	Missense_Mutation	novel	S1406Y	0.33
UCEC	chr18	33744448	Missense_Mutation	novel	D1534Y	0.4
UCEC	chr18	33746638	3'UTR	novel		0.42
UCEC	chr18	33743802	Missense_Mutation	novel	M1318I	0.26
UCEC	chr18	33746424	Silent	rs373489061	N2192N	0.41
UCEC	chr18	33744084	Silent	rs756320994	T1412T	0.35
UCEC	chr18	33745600	Missense_Mutation	rs768844047	G1918S	0.19
UCEC	chr18	33661646	Missense_Mutation	novel	S129Y	0.49
UCEC	chr18	33683418	Missense_Mutation	novel	W243C	0.52
UCEC	chr18	33734309	Splice_Site	novel	X326_splice	0.53
UCEC	chr18	33743160	Silent	NA	E1104E	0.43
UCEC	chr18	33743564	Missense_Mutation	novel	S1239Y	0.39
UCEC	chr18	33744529	Nonsense_Mutation	novel	E1561*	0.44
UCEC	chr18	33745782	Silent	novel	S1978S	0.54
UCEC	chr18	33740022	Frame_Shift_Del	NA	*V876Cfs59**	0.35
UCEC	chr18	33744664	Silent	novel	R1606R	0.33
UCEC	chr18	33743208	Silent	NA	L1120L	0.14
UCEC	chr18	33745650	Missense_Mutation	rs752274733	M1934I	0.49
UCEC	chr18	33683420	Missense_Mutation	NA	T244I	0.29
UCEC	chr18	33732040	Missense_Mutation	NA	G318W	0.11
UCEC	chr18	33739883	Missense_Mutation	novel	D827Y	0.09
UCEC	chr18	33740151	Missense_Mutation	NA	F916S	0.38
UCEC	chr18	33744544	Missense_Mutation	NA	P1566S	0.33
UCEC	chr18	33745530	Silent	NA	V1894V	0.31
UCEC	chr18	33744650	Missense_Mutation	novel	Y1601C	0.21
UCEC	chr18	33740022	Frame_Shift_Del	NA	*V876Cfs59**	0.33
UCEC	chr18	33734324	Nonsense_Mutation	novel	E331*	0.33
UCEC	chr18	33740190	Missense_Mutation	novel	S929N	0.38
UCEC	chr18	33738724	Missense_Mutation	novel	E440D	0.07
UCEC	chr18	33743231	Missense_Mutation	rs772559746	R1128Q	0.43
UCEC	chr18	33744069	Silent	novel	L1407L	0.22
UCEC	chr18	33740022	Frame_Shift_Del	NA	*V876Cfs59**	0.19
UCEC	chr18	33739983	Missense_Mutation	rs61734121	M860T	0.26
UCEC	chr18	33746761	3'UTR	novel		0.67
UCEC	chr18	33742982	Missense_Mutation	NA	G1045D	0.11
UCEC	chr18	33746730	3'UTR	novel		0.67
UCEC	chr18	33734365	Missense_Mutation	NA	K344N	0.44
UCEC	chr18	33739441	Missense_Mutation	NA	E679D	0.47
UCEC	chr18	33740340	Missense_Mutation	NA	R979I	0.45
UCEC	chr18	33744766	Missense_Mutation	NA	K1640Q	0.51
UCEC	chr18	33745790	Missense_Mutation	NA	P1981L	0.78
UCEC	chr18	33607669	Nonsense_Mutation	NA	E44*	0.38	HARE-HTH
UCEC	chr18	33745151	Missense_Mutation	NA	R1768I	0.24
UCEC	chr18	33745545	Frame_Shift_Ins	novel	*S1903Cfs85**	0.18
UCEC	chr18	33670703	Nonsense_Mutation	NA	G170*	0.35
UCEC	chr18	33740443	Missense_Mutation	NA	K1013N	0.24
UCEC	chr18	33743536	Frame_Shift_Del	novel	*L1230Ffs26**	0.35
UCEC	chr18	33744179	Missense_Mutation	rs548755448	R1444Q	0.19
UCEC	chr18	33746452	Missense_Mutation	rs190401191	D2202N	0.28
UCEC	chr18	33743275	Nonsense_Mutation	novel	E1143*	0.29
UCEC	chr18	33683511	Silent	novel	S274S	0.2
UCEC	chr18	33731990	Missense_Mutation	rs768502867	R301H	0.41
UCEC	chr18	33738974	Nonsense_Mutation	novel	E524*	0.15
UCEC	chr18	33742984	Missense_Mutation	rs376997378	G1046R	0.48
UCEC	chr18	33745291	Missense_Mutation	novel	L1815M	0.41
UCEC	chr18	33745437	Silent	rs372236988	S1863S	0.41
UCEC	chr18	33745772	Missense_Mutation	novel	V1975A	0.19
UCEC	chr18	33740091	Missense_Mutation	novel	E896V	0.17
UCEC	chr18	33661720	Frame_Shift_Del	novel	*K155Rfs7**	0.41
UCEC	chr18	33745819	Missense_Mutation	novel	S1991P	0.43
UCEC	chr18	33746018	Missense_Mutation	novel	P2057H	0.21
UCEC	chr18	33743034	Missense_Mutation	novel	Q1062H	0.46
UCEC	chr18	33743599	Nonsense_Mutation	novel	E1251*	0.35
UCEC	chr18	33746437	Missense_Mutation	rs778221486	V2197I	0.35
UCEC	chr18	33578675	Missense_Mutation	novel	A15D	0.34	HARE-HTH
UCEC	chr18	33670777	Silent	novel	S194S	0.21
UCEC	chr18	33738804	Missense_Mutation	novel	D467G	0.54
UCEC	chr18	33739021	Silent	novel	V539V	0.4
UCEC	chr18	33742930	Nonsense_Mutation	novel	Q1028*	0.52
UCEC	chr18	33744327	Silent	novel	S1493S	0.43
UCEC	chr18	33744509	Missense_Mutation	novel	A1554V	0.31
UCS	chr18	33745534	Missense_Mutation	novel	Q1896K	0.06
UCS	chr18	33746668	3'UTR	novel		0.43
UCS	chr18	33744319	Missense_Mutation	rs751537958	V1491I	0.31
UVM	chr18	33743366	Missense_Mutation	novel	A1173V	0.46

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0001	Kaplan-Meier Survival Analysis
ACC	0.0097	Kaplan-Meier Survival Analysis
LUSC	0.016	Kaplan-Meier Survival Analysis
BRCA	0.031	Kaplan-Meier Survival Analysis
KIRP	0.0034	Kaplan-Meier Survival Analysis
PAAD	0.0038	Kaplan-Meier Survival Analysis
LAML	0.018	Kaplan-Meier Survival Analysis
UCEC	0.0014	Kaplan-Meier Survival Analysis
GBM	0.018	Kaplan-Meier Survival Analysis
LIHC	0.05	Kaplan-Meier Survival Analysis
LGG	0.00012	Kaplan-Meier Survival Analysis
CHOL	0.005	Kaplan-Meier Survival Analysis
THCA	0.003	Kaplan-Meier Survival Analysis
LUAD	0.045	Kaplan-Meier Survival Analysis
OV	0.031	Kaplan-Meier Survival Analysis

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000141431 (Gene tree)
Gene ID: 80816
Gene Symbol: ASXL3
Alias: KIAA1713
Full Name: ASXL transcriptional regulator 3
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 172,963 bases
Position: chr18:33,578,233-33,751,195
Accession: 29357
RBP type: canonical RBP
Summary: This gene encodes a protein containing a plant homeodomain (PHD) zinc finger domain that plays a role in the regulation of gene transcription. The encoded protein has been shown to negatively regulate lipogenesis by binding to and inhibiting the transcriptional activity of two nuclear hormone receptors, oxysterols receptor LXR-alpha (LXRalpha) and thyroid hormone receptor beta (TRbeta). The encoded protein may also inhibit histone deubiquitination. Mutations in this gene have been identified in human patients with Bainbridge-Ropers syndrome, which is characterized by feeding difficulties, developmental delay and other features. [provided by RefSeq, May 2017]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000269197	HARE-HTH	PF05066.13	7.5e-18	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000269197	ASXL3-201	11743	XM_005258356	ENSP00000269197	2248 (aa)	XP_005258413	Q9C0F0
ENST00000588038	ASXL3-205	572	-	-	- (aa)	-	-
ENST00000593195	ASXL3-212	3968	-	ENSP00000466073	61 (aa)	-	K7ELG8
ENST00000590225	ASXL3-207	546	-	-	- (aa)	-	-
ENST00000590973	ASXL3-208	571	-	-	- (aa)	-	-
ENST00000586948	ASXL3-204	468	-	-	- (aa)	-	-
ENST00000592288	ASXL3-209	3819	-	ENSP00000465053	318 (aa)	-	K7EJ76
ENST00000647014	ASXL3-215	724	-	-	- (aa)	-	-
ENST00000593235	ASXL3-213	493	-	-	- (aa)	-	-
ENST00000642541	ASXL3-214	4216	XM_011526209	ENSP00000493665	1191 (aa)	XP_011524511	A0A2R8Y461
ENST00000592349	ASXL3-210	558	-	-	- (aa)	-	-
ENST00000585426	ASXL3-202	653	-	-	- (aa)	-	-
ENST00000586327	ASXL3-203	559	-	-	- (aa)	-	-
ENST00000592541	ASXL3-211	3661	-	ENSP00000466655	85 (aa)	-	K7EMU6
ENST00000590189	ASXL3-206	843	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000141431's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000141431	Lipoprotein(a)	8.6790000E-005	-
ENSG00000141431	Potassium	5.6950000E-005	-
ENSG00000141431	Platelet Function Tests	2.8051400E-005	-
ENSG00000141431	Platelet Function Tests	1.6838100E-005	-
ENSG00000141431	Platelet Function Tests	6.4037139E-006	-
ENSG00000141431	Respiratory Function Tests	7E-6	23932459
ENSG00000141431	Vital Capacity	7E-6	23932459
ENSG00000141431	Emotions	8E-6	27089181
ENSG00000141431	Emotions	5E-6	27089181
ENSG00000141431	Emotions	4E-6	27089181
ENSG00000141431	Asthma	7E-6	25918132
ENSG00000141431	Toluene 2,4-Diisocyanate	7E-6	25918132
ENSG00000141431	Antidepressive Agents	4E-6	20360315
ENSG00000141431	Antibodies	8E-6	24324551
ENSG00000141431	Trypanosoma cruzi	8E-6	24324551
ENSG00000141431	Asthma	5E-6	25918132
ENSG00000141431	Toluene 2,4-Diisocyanate	5E-6	25918132

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000141431	rs55916387	18	33666280	?	Antibody status in Tripanosoma cruzi seropositivity	24324551			EFO_0004556\|EFO_0005530
ENSG00000141431	rs4799710	18	33686777	?	Pulmonary function	23932459			EFO_0003892\|EFO_0004312
ENSG00000141431	rs7228141	18	33634986	G	Highest math class taken	30038396	[0.0092-0.0182] unit increase	0.0137	EFO_0004875
ENSG00000141431	rs12957987	18	33632245	A	Educational attainment (MTAG)	30038396	[0.0063-0.0113] unit increase	0.0088	EFO_0004784
ENSG00000141431	rs8084619	18	33628696	A	Highest math class taken (MTAG)	30038396	[0.0084-0.015] unit increase	0.0117	EFO_0004875
ENSG00000141431	rs16964886	18	33742030	A	Diisocyanate-induced asthma	25918132	[2.62-17.46]	6.77	EFO_0006995\|EFO_0000270
ENSG00000141431	rs11081818	18	33671124	A	Body mass index	30108127	[NR] unit increase	0.014	EFO_0004340
ENSG00000141431	rs12953422	18	33612565	A	Educational attainment (years of education)	30038396	[0.0053-0.0107] unit decrease	0.008	EFO_0004784
ENSG00000141431	rs7226575	18	33589018	T	Systolic blood pressure	30578418	[0.21-0.39] mmHg decrease	0.2999	EFO_0006335
ENSG00000141431	rs6507054	18	33668359	?	Body mass index	30595370			EFO_0004340
ENSG00000141431	rs10164193	18	33581462	T	Diastolic blood pressure	30224653	[0.16-0.28] mmHg decrease	0.2196	EFO_0006336
ENSG00000141431	rs1155156	18	33714297	A	Life satisfaction	30643256	[0.0056-0.0105] unit increase	0.008061787	EFO_0007869

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000141431's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000141431	ASXL3	72	68.889	ENSAPOG00000016599	-	73	56.579	Acanthochromis_polyacanthus
ENSG00000141431	ASXL3	75	63.043	ENSACIG00000016887	-	85	68.056	Amphilophus_citrinellus
ENSG00000141431	ASXL3	72	68.889	ENSACIG00000013802	-	60	56.579	Amphilophus_citrinellus
ENSG00000141431	ASXL3	72	68.889	ENSAPEG00000014832	-	73	56.579	Amphiprion_percula
ENSG00000141431	ASXL3	72	68.889	ENSATEG00000000035	-	68	56.579	Anabas_testudineus
ENSG00000141431	ASXL3	84	91.045	ENSACAG00000017883	ASXL3	100	66.310	Anolis_carolinensis
ENSG00000141431	ASXL3	59	61.111	ENSACAG00000012597	-	74	64.103	Anolis_carolinensis
ENSG00000141431	ASXL3	100	96.474	ENSANAG00000034397	ASXL3	99	95.432	Aotus_nancymaae
ENSG00000141431	ASXL3	72	71.111	ENSANAG00000032163	ASXL1	100	66.667	Aotus_nancymaae
ENSG00000141431	ASXL3	100	87.280	ENSBTAG00000047003	ASXL3	91	96.350	Bos_taurus
ENSG00000141431	ASXL3	72	71.111	ENSCJAG00000020708	ASXL1	100	68.421	Callithrix_jacchus
ENSG00000141431	ASXL3	100	95.634	ENSCJAG00000020922	ASXL3	99	95.623	Callithrix_jacchus
ENSG00000141431	ASXL3	100	90.940	ENSCAFG00000017980	ASXL3	100	89.267	Canis_familiaris
ENSG00000141431	ASXL3	99	85.276	ENSCAFG00020011763	-	89	90.429	Canis_lupus_dingo
ENSG00000141431	ASXL3	100	87.531	ENSCHIG00000000206	ASXL3	99	85.078	Capra_hircus
ENSG00000141431	ASXL3	100	91.107	ENSTSYG00000009121	ASXL3	99	91.153	Carlito_syrichta
ENSG00000141431	ASXL3	69	50.000	ENSCAPG00000016451	-	56	64.615	Cavia_aperea
ENSG00000141431	ASXL3	80	64.000	ENSCPOG00000007343	ASXL2	58	48.718	Cavia_porcellus
ENSG00000141431	ASXL3	84	65.385	ENSCCAG00000023224	ASXL1	100	66.667	Cebus_capucinus
ENSG00000141431	ASXL3	100	95.718	ENSCCAG00000010303	ASXL3	99	95.757	Cebus_capucinus
ENSG00000141431	ASXL3	100	96.558	ENSCATG00000040823	ASXL3	100	96.448	Cercocebus_atys
ENSG00000141431	ASXL3	90	43.464	ENSCATG00000034343	ASXL1	100	66.667	Cercocebus_atys
ENSG00000141431	ASXL3	80	64.000	ENSCLAG00000011428	ASXL2	58	48.974	Chinchilla_lanigera
ENSG00000141431	ASXL3	100	96.641	ENSCANG00000020882	ASXL3	100	96.507	Colobus_angolensis_palliatus
ENSG00000141431	ASXL3	86	42.034	ENSCANG00000030372	ASXL1	100	66.667	Colobus_angolensis_palliatus
ENSG00000141431	ASXL3	84	61.538	ENSCGRG00000018294	Asxl2	58	48.698	Cricetulus_griseus_crigri
ENSG00000141431	ASXL3	72	68.889	ENSCSEG00000004640	-	78	56.579	Cynoglossus_semilaevis
ENSG00000141431	ASXL3	84	63.462	ENSCVAG00000011364	-	68	56.579	Cyprinodon_variegatus
ENSG00000141431	ASXL3	52	59.375	ENSDORG00000028887	-	82	63.235	Dipodomys_ordii
ENSG00000141431	ASXL3	100	86.600	ENSDORG00000026299	Asxl3	99	86.250	Dipodomys_ordii
ENSG00000141431	ASXL3	84	56.863	ENSEBUG00000015628	-	85	43.182	Eptatretus_burgeri
ENSG00000141431	ASXL3	100	90.856	ENSEASG00005016631	ASXL3	99	90.645	Equus_asinus_asinus
ENSG00000141431	ASXL3	100	90.772	ENSFCAG00000024545	ASXL3	99	89.701	Felis_catus
ENSG00000141431	ASXL3	84	91.045	ENSFALG00000005882	ASXL3	99	69.720	Ficedula_albicollis
ENSG00000141431	ASXL3	77	61.702	ENSGMOG00000004155	-	92	46.076	Gadus_morhua
ENSG00000141431	ASXL3	75	68.085	ENSGMOG00000009096	-	57	44.444	Gadus_morhua
ENSG00000141431	ASXL3	89	91.228	ENSGALG00000015196	ASXL3	100	71.632	Gallus_gallus
ENSG00000141431	ASXL3	75	68.085	ENSGAFG00000014909	-	82	55.696	Gambusia_affinis
ENSG00000141431	ASXL3	72	68.889	ENSGACG00000012822	asxl1	52	45.407	Gasterosteus_aculeatus
ENSG00000141431	ASXL3	84	92.910	ENSGAGG00000023753	ASXL3	100	71.909	Gopherus_agassizii
ENSG00000141431	ASXL3	79	62.500	ENSGAGG00000020819	ASXL1	50	50.133	Gopherus_agassizii
ENSG00000141431	ASXL3	87	41.751	ENSGGOG00000003328	ASXL1	100	66.667	Gorilla_gorilla
ENSG00000141431	ASXL3	100	99.328	ENSGGOG00000003118	ASXL3	99	99.021	Gorilla_gorilla
ENSG00000141431	ASXL3	84	61.538	ENSHGLG00000006048	ASXL2	60	49.373	Heterocephalus_glaber_female
ENSG00000141431	ASXL3	80	68.000	ENSHGLG00000017863	-	71	68.056	Heterocephalus_glaber_female
ENSG00000141431	ASXL3	84	61.538	ENSHGLG00100010557	ASXL2	60	49.373	Heterocephalus_glaber_male
ENSG00000141431	ASXL3	72	68.889	ENSHCOG00000013253	-	68	56.579	Hippocampus_comes
ENSG00000141431	ASXL3	75	43.478	ENSJJAG00000021569	-	71	61.194	Jaculus_jaculus
ENSG00000141431	ASXL3	75	68.085	ENSKMAG00000013765	-	83	57.333	Kryptolebias_marmoratus
ENSG00000141431	ASXL3	72	68.889	ENSLBEG00000012396	-	86	54.762	Labrus_bergylta
ENSG00000141431	ASXL3	80	93.878	ENSLOCG00000006197	ASXL3	57	69.777	Lepisosteus_oculatus
ENSG00000141431	ASXL3	100	97.061	ENSMFAG00000032715	ASXL3	100	96.801	Macaca_fascicularis
ENSG00000141431	ASXL3	90	43.464	ENSMFAG00000029400	ASXL1	100	66.667	Macaca_fascicularis
ENSG00000141431	ASXL3	100	96.893	ENSMMUG00000014451	ASXL3	100	96.713	Macaca_mulatta
ENSG00000141431	ASXL3	90	43.464	ENSMMUG00000007117	ASXL1	100	66.667	Macaca_mulatta
ENSG00000141431	ASXL3	87	41.275	ENSMNEG00000031201	ASXL1	100	66.667	Macaca_nemestrina
ENSG00000141431	ASXL3	100	96.641	ENSMNEG00000041270	ASXL3	100	96.490	Macaca_nemestrina
ENSG00000141431	ASXL3	91	41.613	ENSMLEG00000024749	ASXL1	100	66.667	Mandrillus_leucophaeus
ENSG00000141431	ASXL3	100	96.893	ENSMLEG00000030306	ASXL3	100	95.833	Mandrillus_leucophaeus
ENSG00000141431	ASXL3	72	68.889	ENSMAMG00000008791	-	85	56.579	Mastacembelus_armatus
ENSG00000141431	ASXL3	84	91.045	ENSMGAG00000010637	ASXL3	100	70.701	Meleagris_gallopavo
ENSG00000141431	ASXL3	89	94.366	ENSMAUG00000010440	Asxl3	99	81.943	Mesocricetus_auratus
ENSG00000141431	ASXL3	75	70.213	ENSMAUG00000000537	-	53	68.056	Mesocricetus_auratus
ENSG00000141431	ASXL3	100	92.701	ENSMICG00000031715	ASXL3	99	92.194	Microcebus_murinus
ENSG00000141431	ASXL3	100	81.925	ENSMOCG00000020273	Asxl3	99	81.453	Microtus_ochrogaster
ENSG00000141431	ASXL3	80	68.000	ENSMOCG00000014066	-	85	68.056	Microtus_ochrogaster
ENSG00000141431	ASXL3	75	68.085	ENSMMOG00000017515	-	80	57.333	Mola_mola
ENSG00000141431	ASXL3	89	94.737	ENSMODG00000010795	ASXL3	99	76.104	Monodelphis_domestica
ENSG00000141431	ASXL3	72	68.889	ENSMALG00000021361	-	81	54.762	Monopterus_albus
ENSG00000141431	ASXL3	84	59.615	MGP_CAROLIEiJ_G0017573	Asxl2	93	49.734	Mus_caroli
ENSG00000141431	ASXL3	84	59.615	ENSMUSG00000037486	Asxl2	96	49.620	Mus_musculus
ENSG00000141431	ASXL3	80	64.000	MGP_SPRETEiJ_G0018417	Asxl2	93	49.740	Mus_spretus
ENSG00000141431	ASXL3	100	84.396	ENSNGAG00000016058	Asxl3	99	81.551	Nannospalax_galili
ENSG00000141431	ASXL3	75	68.085	ENSNBRG00000021565	-	87	51.807	Neolamprologus_brichardi
ENSG00000141431	ASXL3	100	98.321	ENSNLEG00000006333	ASXL3	100	97.868	Nomascus_leucogenys
ENSG00000141431	ASXL3	86	42.712	ENSNLEG00000009794	ASXL1	100	66.667	Nomascus_leucogenys
ENSG00000141431	ASXL3	100	87.930	ENSODEG00000018431	ASXL3	99	87.589	Octodon_degus
ENSG00000141431	ASXL3	75	70.213	ENSODEG00000012381	-	88	59.341	Octodon_degus
ENSG00000141431	ASXL3	84	94.030	ENSOANG00000005610	-	98	70.945	Ornithorhynchus_anatinus
ENSG00000141431	ASXL3	100	88.507	ENSOCUG00000010832	ASXL3	100	88.824	Oryctolagus_cuniculus
ENSG00000141431	ASXL3	75	68.085	ENSORLG00000027477	-	84	57.333	Oryzias_latipes
ENSG00000141431	ASXL3	75	68.085	ENSORLG00020003431	-	84	57.333	Oryzias_latipes_hni
ENSG00000141431	ASXL3	75	68.085	ENSORLG00015017723	-	84	57.333	Oryzias_latipes_hsok
ENSG00000141431	ASXL3	72	52.273	ENSORLG00015003122	-	74	68.254	Oryzias_latipes_hsok
ENSG00000141431	ASXL3	75	68.085	ENSOMEG00000011176	-	59	57.333	Oryzias_melastigma
ENSG00000141431	ASXL3	100	85.356	ENSOARG00000005872	ASXL3	100	83.609	Ovis_aries
ENSG00000141431	ASXL3	86	42.373	ENSPPAG00000028038	ASXL1	100	66.667	Pan_paniscus
ENSG00000141431	ASXL3	100	99.496	ENSPPAG00000027991	ASXL3	100	99.238	Pan_paniscus
ENSG00000141431	ASXL3	100	90.688	ENSPPRG00000025087	ASXL3	99	89.549	Panthera_pardus
ENSG00000141431	ASXL3	100	89.513	ENSPTIG00000010175	ASXL3	100	86.705	Panthera_tigris_altaica
ENSG00000141431	ASXL3	54	51.515	ENSPTIG00000008552	-	85	63.636	Panthera_tigris_altaica
ENSG00000141431	ASXL3	90	43.791	ENSPTRG00000013377	ASXL1	100	66.667	Pan_troglodytes
ENSG00000141431	ASXL3	100	99.580	ENSPTRG00000009962	ASXL3	100	99.378	Pan_troglodytes
ENSG00000141431	ASXL3	90	43.464	ENSPANG00000025544	ASXL1	100	66.667	Papio_anubis
ENSG00000141431	ASXL3	100	96.809	ENSPANG00000007343	ASXL3	100	96.490	Papio_anubis
ENSG00000141431	ASXL3	59	80.142	ENSPKIG00000000956	ASXL3	53	75.510	Paramormyrops_kingsleyae
ENSG00000141431	ASXL3	75	65.217	ENSPMGG00000024122	-	83	68.056	Periophthalmus_magnuspinnatus
ENSG00000141431	ASXL3	75	70.213	ENSPMGG00000017948	-	74	58.667	Periophthalmus_magnuspinnatus
ENSG00000141431	ASXL3	89	94.718	ENSPEMG00000014301	Asxl3	99	82.387	Peromyscus_maniculatus_bairdii
ENSG00000141431	ASXL3	89	35.331	ENSPMAG00000000240	-	99	40.602	Petromyzon_marinus
ENSG00000141431	ASXL3	75	68.085	ENSPLAG00000004055	-	85	51.389	Poecilia_latipinna
ENSG00000141431	ASXL3	75	68.085	ENSPMEG00000000899	-	72	57.333	Poecilia_mexicana
ENSG00000141431	ASXL3	75	68.085	ENSPREG00000008490	-	75	57.333	Poecilia_reticulata
ENSG00000141431	ASXL3	75	63.043	ENSPREG00000014267	-	85	68.056	Poecilia_reticulata
ENSG00000141431	ASXL3	99	90.331	ENSPCOG00000024916	ASXL3	99	90.331	Propithecus_coquereli
ENSG00000141431	ASXL3	70	60.465	ENSRBIG00000038437	-	100	66.667	Rhinopithecus_bieti
ENSG00000141431	ASXL3	100	96.809	ENSRBIG00000029166	ASXL3	100	94.744	Rhinopithecus_bieti
ENSG00000141431	ASXL3	87	41.414	ENSRROG00000000172	ASXL1	100	66.667	Rhinopithecus_roxellana
ENSG00000141431	ASXL3	100	96.809	ENSRROG00000045627	ASXL3	100	96.132	Rhinopithecus_roxellana
ENSG00000141431	ASXL3	87	41.892	ENSSBOG00000023781	ASXL1	100	66.667	Saimiri_boliviensis_boliviensis
ENSG00000141431	ASXL3	100	95.550	ENSSBOG00000031872	ASXL3	100	95.522	Saimiri_boliviensis_boliviensis
ENSG00000141431	ASXL3	75	68.085	ENSSFOG00015020389	-	71	51.111	Scleropages_formosus
ENSG00000141431	ASXL3	75	68.085	ENSSMAG00000003213	-	85	51.724	Scophthalmus_maximus
ENSG00000141431	ASXL3	75	68.085	ENSSDUG00000000824	-	51	57.333	Seriola_dumerili
ENSG00000141431	ASXL3	86	88.772	ENSSPUG00000006158	-	99	88.772	Sphenodon_punctatus
ENSG00000141431	ASXL3	100	88.842	ENSSSCG00000003736	ASXL3	99	87.388	Sus_scrofa
ENSG00000141431	ASXL3	51	67.742	ENSTGUG00000014522	-	97	70.312	Taeniopygia_guttata
ENSG00000141431	ASXL3	87	90.614	ENSTGUG00000010779	ASXL3	100	69.635	Taeniopygia_guttata
ENSG00000141431	ASXL3	86	40.753	ENSTGUG00000006483	ASXL1	55	48.634	Taeniopygia_guttata
ENSG00000141431	ASXL3	75	68.085	ENSTRUG00000021192	-	77	57.333	Takifugu_rubripes
ENSG00000141431	ASXL3	66	50.000	ENSUAMG00000023398	-	78	61.972	Ursus_americanus
ENSG00000141431	ASXL3	80	64.000	ENSUAMG00000027962	ASXL2	58	48.953	Ursus_americanus
ENSG00000141431	ASXL3	51	64.516	ENSUMAG00000022345	ASXL2	57	48.396	Ursus_maritimus
ENSG00000141431	ASXL3	100	89.262	ENSUMAG00000001778	ASXL3	100	86.119	Ursus_maritimus
ENSG00000141431	ASXL3	100	91.275	ENSVVUG00000027494	ASXL3	100	89.178	Vulpes_vulpes
ENSG00000141431	ASXL3	89	89.510	ENSXETG00000020547	asxl3	97	74.937	Xenopus_tropicalis
ENSG00000141431	ASXL3	75	63.043	ENSXCOG00000001543	-	77	68.056	Xiphophorus_couchianus
ENSG00000141431	ASXL3	75	68.085	ENSXCOG00000008255	-	78	57.333	Xiphophorus_couchianus
ENSG00000141431	ASXL3	75	68.085	ENSXMAG00000024079	-	78	57.333	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000790	nuclear chromatin	21873635.	IBA	Component
GO:0003677	DNA binding	-	IEA	Function
GO:0003682	chromatin binding	21873635.	IBA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0006351	transcription, DNA-templated	-	IEA	Process
GO:0009887	animal organ morphogenesis	21873635.	IBA	Process
GO:0035517	PR-DUB complex	21873635.	IBA	Component
GO:0042975	peroxisome proliferator activated receptor binding	21873635.	IBA	Function
GO:0045944	positive regulation of transcription by RNA polymerase II	21873635.	IBA	Process
GO:0046872	metal ion binding	-	IEA	Function

Note: Click here to get the extension of tumor abbreviations.

Note: to get the extension of tumor abbreviations.