EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
20133759	HUNK suppresses metastasis of basal type breast cancers by disrupting the interaction between PP2A and cofilin-1.	Proc Natl Acad Sci U S A	2010 Feb 9	Quintela-Fandino M	doi: 10.1073/pnas.0914492107
15575376	[Proteinkinase MAK-V/Hunk as a possible dianostic and prognostic marker of human breast carcinoma].	Arkh Patol	2004 Sep-Oct	Korobko IV	-
19717424	The Snf1-related kinase, Hunk, is essential for mammary tumor metastasis.	Proc Natl Acad Sci U S A	2009 Sep 15	Wertheim GB	doi: 10.1073/pnas.0906993106
25515931	Regulation of cell survival by HUNK mediates breast cancer resistance to HER2 inhibitors.	Breast Cancer Res Treat	2015 Jan	Yeh ES	doi: 10.1007/s10549-014-3227-9
28189783	Hormonally up-regulated neu-associated kinase: A novel target for breast cancer progression.	Pharmacol Res	2017 May	Zambrano JN	doi: 10.1016/j.phrs.2017.02.007

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr21	31999000	Missense_Mutation	novel	P654R	0.27
BLCA	chr21	31995942	Missense_Mutation	NA	D494Y	0.26
BLCA	chr21	31924618	Silent	NA	L138L	0.22
BLCA	chr21	31999018	Missense_Mutation	rs749763269	R660Q	0.12
BLCA	chr21	31946081	Missense_Mutation	novel	P219L	0.18
BLCA	chr21	31924745	Missense_Mutation	NA	A180V	0.45	RIO1
BLCA	chr21	31924557	Missense_Mutation	novel	M117I	0.2
BLCA	chr21	31999238	3'UTR	novel		0.5
BLCA	chr21	31998738	Missense_Mutation	rs141493785	R567C	0.92
BLCA	chr21	31924728	Silent	rs769707930	V174V	0.15
BLCA	chr21	31958887	Missense_Mutation	rs576162040	T264M	0.13
BRCA	chr21	31999078	Missense_Mutation	novel	Q680L	0.11
BRCA	chr21	31958877	Silent	NA	L261L	0.13
BRCA	chr21	32000564	3'UTR	novel		0.12
BRCA	chr21	31998701	Silent	novel	L554L	0.06
BRCA	chr21	31998901	Missense_Mutation	novel	S621C	0.15
BRCA	chr21	31995865	Nonsense_Mutation	novel	S468*	0.22
BRCA	chr21	31940180	Missense_Mutation	NA	E190D	0.12	RIO1
CESC	chr21	31998665	Silent	novel	P542P	0.35
CESC	chr21	31999023	Missense_Mutation	rs190270753	R662W	0.27
CESC	chr21	31998769	Missense_Mutation	NA	S577F	0.27
CESC	chr21	32000298	3'UTR	novel		0.55
CESC	chr21	31974573	Silent	NA	L343L	0.3
COAD	chr21	31998849	Missense_Mutation	NA	P604S	0.26
COAD	chr21	31995858	Missense_Mutation	novel	Q466K	0.34
COAD	chr21	31924741	Missense_Mutation	NA	R179W	0.34	RIO1
COAD	chr21	31999063	In_Frame_Ins	novel	H676_Q677insHH	0.14
COAD	chr21	31924749	Silent	novel	G181G	0.05
COAD	chr21	31998962	Silent	rs147755076	P641P	0.26
COAD	chr21	31999025	Silent	NA	R662R	0.2
COAD	chr21	31998721	Missense_Mutation	novel	S561C	0.07
COAD	chr21	31995916	Missense_Mutation	rs769777844	R485Q	0.31
COAD	chr21	31946113	Missense_Mutation	NA	A230T	0.17
COAD	chr21	31924501	Frame_Shift_Del	novel	*K100Rfs18**	0.51
COAD	chr21	31958870	Silent	rs760097878	T258T	0.09
COAD	chr21	31924601	Missense_Mutation	rs761716649	T132M	0.4
COAD	chr21	31924534	Nonsense_Mutation	NA	R110*	0.35
COAD	chr21	31958876	Silent	rs775557579	T260T	0.42
COAD	chr21	31999176	Nonsense_Mutation	rs778884120	Q713*	0.28
DLBC	chr21	31998923	Silent	novel	N628N	0.34
DLBC	chr21	31998756	Missense_Mutation	rs769352625	V573M	0.38
DLBC	chr21	31946157	Silent	rs774875015	I244I	0.19
ESCA	chr21	31968374	Silent	novel	T333T	0.2
ESCA	chr21	31974633	Missense_Mutation	novel	I363M	0.17
ESCA	chr21	31999808	3'UTR	novel		0.12
ESCA	chr21	31999962	3'UTR	novel		0.46
ESCA	chr21	32001926	3'UTR	novel		0.26
GBM	chr21	31924561	Missense_Mutation	rs775412939	R119C	0.28
GBM	chr21	31968376	Frame_Shift_Ins	novel	*P335Sfs60**	0.11
GBM	chr21	31924561	Missense_Mutation	rs775412939	R119C	0.08
GBM	chr21	31995800	Silent	novel	G446G	0.16
GBM	chr21	31958933	Missense_Mutation	NA	D279E	0.23
HNSC	chr21	31958875	Missense_Mutation	rs554519222	T260M	0.37
HNSC	chr21	31999070	Missense_Mutation	novel	Q677H	0.33
HNSC	chr21	31924559	Missense_Mutation	novel	I118T	0.49
HNSC	chr21	31974604	Nonsense_Mutation	novel	K354*	0.29
KIRC	chr21	31968267	Missense_Mutation	rs534370710	R298C	0.19
KIRP	chr21	31998871	Missense_Mutation	novel	L611H	0.85
KIRP	chr21	31924743	Silent	novel	R179R	0.28
KIRP	chr21	31999050	Missense_Mutation	NA	M671L	0.32
LAML	chr21	31974576	Silent	novel	S344S	0.45
LGG	chr21	31999160	Silent	rs754132615	A707A	0.34
LIHC	chr21	31995896	Silent	novel	T478T	0.19
LIHC	chr21	31968383	Missense_Mutation	NA	N336K	0.33
LIHC	chr21	31924535	Missense_Mutation	NA	R110Q	0.14
LIHC	chr21	31998678	Missense_Mutation	novel	I547F	0.32
LIHC	chr21	31924535	Missense_Mutation	NA	R110Q	0.29
LUAD	chr21	31968309	Nonsense_Mutation	novel	Q312*	0.16
LUAD	chr21	31946068	Missense_Mutation	novel	G215C	0.27
LUAD	chr21	31998711	Missense_Mutation	NA	M558V	0.17
LUAD	chr21	31999063	Missense_Mutation	rs749847029	R675H	0.08
LUAD	chr21	31974608	Missense_Mutation	NA	L355Q	0.4
LUAD	chr21	31946157	Silent	rs774875015	I244I	0.15
LUAD	chr21	31974653	Missense_Mutation	NA	R370P	0.76
LUAD	chr21	31999307	3'UTR	novel		0.29
LUSC	chr21	31998841	Missense_Mutation	novel	P601Q	0.18
LUSC	chr21	31958902	Missense_Mutation	NA	S269I	0.62
LUSC	chr21	31924575	Silent	NA	I123I	0.15
LUSC	chr21	31998566	Silent	novel	D509D	0.14
LUSC	chr21	31998614	Silent	NA	P525P	0.16
LUSC	chr21	31924653	Missense_Mutation	novel	M149I	0.46	RIO1
LUSC	chr21	31995917	Silent	NA	R485R	0.2
LUSC	chr21	31999058	Missense_Mutation	NA	R673S	0.37
LUSC	chr21	31998750	Missense_Mutation	rs780570018	V571I	0.38
LUSC	chr21	31974611	Missense_Mutation	novel	G356V	0.32
LUSC	chr21	31998911	Silent	rs376197217	H624H	0.29
LUSC	chr21	31998589	Missense_Mutation	novel	S517F	0.24
LUSC	chr21	31924657	Missense_Mutation	NA	K151E	0.45	RIO1
LUSC	chr21	31999183	Silent	NA	*715*	0.43
LUSC	chr21	31974560	Missense_Mutation	NA	S339F	0.14
MESO	chr21	31998900	Missense_Mutation	novel	S621A	0.26
OV	chr21	31999086	Missense_Mutation	novel	A683P	0.06
OV	chr21	31995823	Missense_Mutation	NA	S454F	0.15
OV	chr21	31958943	Missense_Mutation	novel	N283Y	0.08
OV	chr21	31998633	Missense_Mutation	novel	V532L	0.06
OV	chr21	31999079	Missense_Mutation	novel	Q680H	0.12
PAAD	chr21	31940172	Missense_Mutation	novel	K188E	0.04	RIO1
PRAD	chr21	31946075	Missense_Mutation	rs773621924	S217L	0.35
PRAD	chr21	31946076	Silent	rs763429549	S217S	0.16
READ	chr21	31958887	Missense_Mutation	rs576162040	T264M	0.29
READ	chr21	31974654	Silent	rs764724200	R370R	0.47
READ	chr21	31998523	Splice_Region	novel		0.39
READ	chr21	31968322	Missense_Mutation	rs755514543	A316V	0.18
SARC	chr21	31998771	Missense_Mutation	rs553993228	H578Y	0.51
SARC	chr21	31999166	Silent	novel	G709G	0.88
SARC	chr21	31946143	Missense_Mutation	novel	Y240H	0.29
SARC	chr21	32000427	3'UTR	novel		0.43
SKCM	chr21	31998930	Missense_Mutation	novel	P631S	0.34
SKCM	chr21	31968271	Missense_Mutation	NA	S299F	0.21
SKCM	chr21	31998888	Missense_Mutation	novel	P617S	0.36
SKCM	chr21	31999169	Silent	novel	V710V	0.16
SKCM	chr21	31999110	Silent	NA	L691L	0.33
SKCM	chr21	31924729	Missense_Mutation	novel	E175K	0.43	RIO1
SKCM	chr21	31968273	Missense_Mutation	novel	L300F	0.34
SKCM	chr21	31999203	3'UTR	novel		0.31
SKCM	chr21	31998821	Silent	novel	S594S	0.31
SKCM	chr21	31946130	Silent	NA	L235L	0.08
SKCM	chr21	31990164	Silent	rs749850263	F431F	0.51
SKCM	chr21	31995920	Missense_Mutation	novel	K486N	0.25
SKCM	chr21	31999164	Missense_Mutation	novel	G709R	0.38
SKCM	chr21	31958892	Missense_Mutation	NA	E266K	0.26
SKCM	chr21	31998738	Missense_Mutation	rs141493785	R567C	0.15
SKCM	chr21	31995792	Nonsense_Mutation	NA	K444*	0.23
SKCM	chr21	31968327	Missense_Mutation	rs192440238	R318C	0.37
SKCM	chr21	31974568	Missense_Mutation	NA	D342N	0.29
SKCM	chr21	31998738	Missense_Mutation	rs141493785	R567C	0.25
SKCM	chr21	31998552	Missense_Mutation	rs184706666	R505C	0.17
SKCM	chr21	31998725	Silent	rs753294374	F562F	0.17
SKCM	chr21	31998722	Silent	NA	S561S	0.14
SKCM	chr21	31990169	Missense_Mutation	NA	A433V	0.11
SKCM	chr21	31998738	Missense_Mutation	rs141493785	R567C	0.31
SKCM	chr21	31968263	Silent	rs562739488	F296F	0.49
SKCM	chr21	31998738	Missense_Mutation	rs141493785	R567C	0.24
STAD	chr21	31998541	Missense_Mutation	rs748171279	R501H	0.55
STAD	chr21	31924709	Missense_Mutation	rs377533874	R168Q	0.24	RIO1
STAD	chr21	31946112	Silent	rs766332712	Y229Y	0.4
STAD	chr21	31998525	Splice_Site	NA	X496_splice	0.23
STAD	chr21	31968322	Missense_Mutation	rs755514543	A316V	0.14
STAD	chr21	31873879	Missense_Mutation	NA	G69C	0.22
STAD	chr21	31968349	Missense_Mutation	rs184771754	T325M	0.2
STAD	chr21	31958875	Missense_Mutation	rs554519222	T260M	0.15
STAD	chr21	31999186	3'UTR	novel		0.16
STAD	chr21	31974598	Missense_Mutation	NA	T352A	0.23
UCEC	chr21	31995902	Silent	novel	A480A	0.26
UCEC	chr21	31924659	Missense_Mutation	NA	K151N	0.26	RIO1
UCEC	chr21	31946048	Missense_Mutation	rs368005070	S208N	0.37
UCEC	chr21	31983603	Silent	novel	S417S	0.16
UCEC	chr21	31998977	Silent	rs756085668	G646G	0.38
UCEC	chr21	32001881	3'UTR	novel		0.34
UCEC	chr21	32002064	3'UTR	novel		0.49
UCEC	chr21	31924665	Silent	novel	Y153Y	0.48
UCEC	chr21	31974594	Silent	novel	H350H	0.2
UCEC	chr21	31998747	Missense_Mutation	NA	H570Y	0.51
UCEC	chr21	32000437	3'UTR	novel		0.14
UCEC	chr21	31998819	Missense_Mutation	novel	S594P	0.09
UCEC	chr21	31995790	Frame_Shift_Del	novel	*R445Efs28**	0.44
UCEC	chr21	31968263	Silent	rs562739488	F296F	0.44
UCEC	chr21	32000605	3'UTR	rs534905306		0.25
UCEC	chr21	31968268	Missense_Mutation	novel	R298H	0.35
UCEC	chr21	31998781	Missense_Mutation	novel	R581M	0.32
UCEC	chr21	32001746	3'UTR	novel		0.42
UCEC	chr21	32001722	3'UTR	novel		0.29
UCEC	chr21	31998854	Silent	rs141071061	S605S	0.26
UCEC	chr21	31974704	Missense_Mutation	rs780565997	R387H	0.29
UCEC	chr21	32000053	3'UTR	novel		0.5
UCEC	chr21	32002076	3'UTR	novel		0.41
UCEC	chr21	31998656	Silent	rs756309521	Q539Q	0.21
UCEC	chr21	31924708	Nonsense_Mutation	NA	R168*	0.55	RIO1
UCEC	chr21	31999023	Missense_Mutation	rs190270753	R662W	0.36
UCEC	chr21	32000118	3'UTR	rs541929144		0.38
UCEC	chr21	31998911	Silent	rs376197217	H624H	0.24
UCEC	chr21	31958911	Missense_Mutation	novel	A272V	0.38
UCEC	chr21	31995942	Missense_Mutation	rs377150590	D494N	0.43
UCEC	chr21	31998926	Frame_Shift_Del	novel	*P631Qfs27**	0.49
UCEC	chr21	32002091	3'UTR	novel		0.4
UCEC	chr21	32001817	3'UTR	novel		0.58
UCEC	chr21	31924708	Nonsense_Mutation	NA	R168*	0.19	RIO1
UCEC	chr21	31924690	Missense_Mutation	novel	E162K	0.65	RIO1
UCEC	chr21	31998911	Silent	rs376197217	H624H	0.39
UCEC	chr21	31924561	Missense_Mutation	rs775412939	R119C	0.45
UCEC	chr21	31946076	Silent	rs763429549	S217S	0.23
UCEC	chr21	31968284	Silent	rs143270998	P303P	0.33
UCEC	chr21	31974654	Silent	rs764724200	R370R	0.29
UCEC	chr21	31946076	Silent	rs763429549	S217S	0.45
UCEC	chr21	32001777	3'UTR	novel		0.45
UCEC	chr21	32002020	3'UTR	novel		0.26
UCEC	chr21	31946135	Missense_Mutation	novel	R237M	0.24
UCEC	chr21	31999819	3'UTR	novel		0.21
UCEC	chr21	32000330	3'UTR	novel		0.26
UCEC	chr21	31958871	Missense_Mutation	NA	G259R	0.32
UCEC	chr21	31924708	Nonsense_Mutation	NA	R168*	0.31	RIO1
UCEC	chr21	31974697	Silent	novel	L385L	0.38
UCEC	chr21	32000382	3'UTR	rs529244817		0.46
UCEC	chr21	32001873	3'UTR	novel		0.37
UCEC	chr21	31946056	Missense_Mutation	novel	A211T	0.3
UCEC	chr21	32000195	3'UTR	novel		0.35
UCEC	chr21	31998683	Silent	novel	P548P	0.17
UCEC	chr21	31999024	Missense_Mutation	rs772115970	R662Q	0.26
UCEC	chr21	32001722	3'UTR	novel		0.33
UCEC	chr21	31924534	Nonsense_Mutation	NA	R110*	0.48
UCEC	chr21	31974654	Silent	rs764724200	R370R	0.2
UCEC	chr21	31998613	Missense_Mutation	rs145984941	P525L	0.19
UCEC	chr21	31998794	Silent	novel	S585S	0.18
UCEC	chr21	31999043	Silent	rs753871470	I668I	0.4
UCEC	chr21	32001841	3'UTR	novel		0.5
UCEC	chr21	31998866	Silent	rs144923714	S609S	0.33
UCEC	chr21	32002098	3'UTR	novel		0.35
UCEC	chr21	31974681	Silent	novel	F379F	0.37
UCEC	chr21	32000203	3'UTR	novel		0.39
UCEC	chr21	32001722	3'UTR	novel		0.72
UCS	chr21	31974632	Missense_Mutation	novel	I363T	0.14

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
CESC	DEL	0.1729	0.19516
PAAD	DEL	0.1848	0.10872

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0001	Kaplan-Meier Survival Analysis
MESO	0.0096	Kaplan-Meier Survival Analysis
ACC	0.022	Kaplan-Meier Survival Analysis
HNSC	0.0021	Kaplan-Meier Survival Analysis
SKCM	0.021	Kaplan-Meier Survival Analysis
KIRP	0.02	Kaplan-Meier Survival Analysis
PCPG	0.015	Kaplan-Meier Survival Analysis
UCEC	0.012	Kaplan-Meier Survival Analysis
LUAD	0.04	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000142149 (Gene tree)
Gene ID: 30811
Gene Symbol: HUNK
Alias: -
Full Name: hormonally up-regulated Neu-associated kinase
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 171,319 bases
Position: chr21:31,873,315-32,044,633
Accession: 13326
RBP type: canonical RBP
Summary: HUNK (Hormonally Up-Regulated Neu-Associated Kinase) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is SIK2.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000411860	RIO1	PF01163.22	2e-05	1	1
ENSP00000270112	RIO1	PF01163.22	0.00013	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000439107	HUNK-203	860	-	ENSP00000408219	112 (aa)	-	H7C2X2
ENST00000270112	HUNK-201	7385	XM_011529537	ENSP00000270112	714 (aa)	XP_011527839	P57058
ENST00000430354	HUNK-202	486	-	ENSP00000411860	162 (aa)	-	H7C3H0
ENST00000465574	HUNK-204	832	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000142149's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000142149	Hemoglobin A, Glycosylated	7.84783516711851E-5	17903298
ENSG00000142149	Neuroblastoma	7.73E-7	18463370
ENSG00000142149	Blood Pressure	5.6210000E-005	-
ENSG00000142149	Platelet Function Tests	2.0700000E-006	-
ENSG00000142149	Child Development Disorders, Pervasive	2.0214700E-005	-
ENSG00000142149	Child Development Disorders, Pervasive	4.3401000E-005	-
ENSG00000142149	Child Development Disorders, Pervasive	2.7675200E-005	-
ENSG00000142149	Child Development Disorders, Pervasive	6.0977400E-005	-
ENSG00000142149	Child Development Disorders, Pervasive	9.4000000E-005	-
ENSG00000142149	Interleukin-8	1.5900000E-005	-
ENSG00000142149	Immunoglobulins	8E-6	23382691
ENSG00000142149	Vitiligo	2E-6	19890347
ENSG00000142149	Logic	5E-7	21107309
ENSG00000142149	Diabetes Mellitus, Type 2	4E-6	21490949

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000142149	rs11910494	21	31923801	G	IgG glycosylation	23382691	[0.083-0.213] unit increase	0.1483	EFO_0005193
ENSG00000142149	rs2833607	21	32008727	?	Vitiligo	19890347			EFO_0004208
ENSG00000142149	rs2833560	21	31915561	?	Measles	28928442	[0.059-0.142] unit increase	0.1009	EFO_0008414
ENSG00000142149	rs2833556	21	31912988	?	Response to antipsychotic treatment in schizophrenia (reasoning)	21107309			EFO_0004350
ENSG00000142149	rs2833610	21	32012873	A	Type 2 diabetes	21490949	[1.09-1.24]	1.17	EFO_0001360
ENSG00000142149	rs2833579	21	31956217	G	Periodontitis	30218097	[1.08-1.21]	1.15	EFO_0000649

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000142149's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000142149	HUNK	97	88.073	ENSAMEG00000018210	HUNK	100	91.101	Ailuropoda_melanoleuca
ENSG00000142149	HUNK	90	91.034	ENSAPLG00000002063	HUNK	98	70.644	Anas_platyrhynchos
ENSG00000142149	HUNK	90	88.276	ENSACAG00000002743	HUNK	100	66.113	Anolis_carolinensis
ENSG00000142149	HUNK	97	96.330	ENSANAG00000026514	-	97	93.398	Aotus_nancymaae
ENSG00000142149	HUNK	100	96.779	ENSANAG00000018665	-	100	96.779	Aotus_nancymaae
ENSG00000142149	HUNK	100	91.049	ENSBTAG00000020762	HUNK	100	91.189	Bos_taurus
ENSG00000142149	HUNK	100	97.199	ENSCJAG00000045743	HUNK	100	97.199	Callithrix_jacchus
ENSG00000142149	HUNK	97	88.991	ENSCAFG00000008874	HUNK	98	90.635	Canis_familiaris
ENSG00000142149	HUNK	100	89.103	ENSCAFG00020026005	HUNK	100	90.345	Canis_lupus_dingo
ENSG00000142149	HUNK	100	90.629	ENSCHIG00000014504	HUNK	100	90.769	Capra_hircus
ENSG00000142149	HUNK	97	87.156	ENSTSYG00000005298	HUNK	100	82.380	Carlito_syrichta
ENSG00000142149	HUNK	97	87.273	ENSCAPG00000011721	HUNK	99	91.415	Cavia_aperea
ENSG00000142149	HUNK	97	87.273	ENSCPOG00000010546	HUNK	100	91.821	Cavia_porcellus
ENSG00000142149	HUNK	100	96.639	ENSCCAG00000028641	HUNK	100	96.639	Cebus_capucinus
ENSG00000142149	HUNK	100	92.629	ENSCATG00000028680	HUNK	100	92.629	Cercocebus_atys
ENSG00000142149	HUNK	98	92.837	ENSCLAG00000005512	HUNK	96	92.982	Chinchilla_lanigera
ENSG00000142149	HUNK	97	98.165	ENSCSAG00000009448	HUNK	100	98.997	Chlorocebus_sabaeus
ENSG00000142149	HUNK	90	90.345	ENSCPBG00000006541	HUNK	100	70.596	Chrysemys_picta_bellii
ENSG00000142149	HUNK	97	100.000	ENSCANG00000041035	HUNK	99	97.293	Colobus_angolensis_palliatus
ENSG00000142149	HUNK	100	92.577	ENSCGRG00001022573	Hunk	100	92.577	Cricetulus_griseus_chok1gshd
ENSG00000142149	HUNK	97	88.991	ENSCGRG00000013678	Hunk	100	92.185	Cricetulus_griseus_crigri
ENSG00000142149	HUNK	100	91.469	ENSDNOG00000039018	HUNK	100	92.168	Dasypus_novemcinctus
ENSG00000142149	HUNK	90	93.793	ENSDORG00000002143	Hunk	98	91.256	Dipodomys_ordii
ENSG00000142149	HUNK	90	93.103	ENSETEG00000011266	HUNK	100	88.712	Echinops_telfairi
ENSG00000142149	HUNK	100	93.147	ENSEASG00005007746	HUNK	100	92.308	Equus_asinus_asinus
ENSG00000142149	HUNK	100	92.168	ENSECAG00000007153	HUNK	100	92.308	Equus_caballus
ENSG00000142149	HUNK	100	92.157	ENSFCAG00000028905	HUNK	100	92.157	Felis_catus
ENSG00000142149	HUNK	90	91.034	ENSFALG00000008061	HUNK	100	73.225	Ficedula_albicollis
ENSG00000142149	HUNK	97	88.182	ENSFDAG00000009486	HUNK	100	90.127	Fukomys_damarensis
ENSG00000142149	HUNK	90	82.069	ENSGMOG00000015028	HUNK	93	74.788	Gadus_morhua
ENSG00000142149	HUNK	90	91.034	ENSGALG00000015879	HUNK	100	67.586	Gallus_gallus
ENSG00000142149	HUNK	89	90.278	ENSGAGG00000002645	HUNK	100	68.377	Gopherus_agassizii
ENSG00000142149	HUNK	97	100.000	ENSGGOG00000016651	HUNK	100	99.841	Gorilla_gorilla
ENSG00000142149	HUNK	100	92.028	ENSHGLG00000014832	HUNK	100	92.028	Heterocephalus_glaber_female
ENSG00000142149	HUNK	100	92.028	ENSHGLG00100007886	HUNK	100	92.028	Heterocephalus_glaber_male
ENSG00000142149	HUNK	100	93.566	ENSSTOG00000024744	HUNK	100	93.566	Ictidomys_tridecemlineatus
ENSG00000142149	HUNK	97	88.991	ENSJJAG00000014419	Hunk	98	93.142	Jaculus_jaculus
ENSG00000142149	HUNK	83	86.567	ENSLOCG00000009175	HUNK	93	49.639	Lepisosteus_oculatus
ENSG00000142149	HUNK	95	89.051	ENSLAFG00000004577	HUNK	100	89.051	Loxodonta_africana
ENSG00000142149	HUNK	97	98.165	ENSMFAG00000043007	HUNK	100	98.829	Macaca_fascicularis
ENSG00000142149	HUNK	100	100.000	ENSMMUG00000012917	HUNK	100	100.000	Macaca_mulatta
ENSG00000142149	HUNK	99	97.335	ENSMNEG00000044157	HUNK	92	97.335	Macaca_nemestrina
ENSG00000142149	HUNK	97	98.165	ENSMLEG00000038042	HUNK	100	99.043	Mandrillus_leucophaeus
ENSG00000142149	HUNK	90	91.034	ENSMGAG00000014513	HUNK	99	70.000	Meleagris_gallopavo
ENSG00000142149	HUNK	100	87.500	ENSMAUG00000018207	Hunk	82	95.354	Mesocricetus_auratus
ENSG00000142149	HUNK	100	90.476	ENSMOCG00000018032	Hunk	100	90.476	Microtus_ochrogaster
ENSG00000142149	HUNK	100	92.577	MGP_CAROLIEiJ_G0020945	Hunk	100	92.577	Mus_caroli
ENSG00000142149	HUNK	100	92.437	ENSMUSG00000053414	Hunk	100	92.437	Mus_musculus
ENSG00000142149	HUNK	100	92.437	MGP_PahariEiJ_G0016650	Hunk	100	91.317	Mus_pahari
ENSG00000142149	HUNK	100	92.577	MGP_SPRETEiJ_G0021851	Hunk	100	92.577	Mus_spretus
ENSG00000142149	HUNK	97	86.239	ENSMPUG00000001113	HUNK	100	90.468	Mustela_putorius_furo
ENSG00000142149	HUNK	100	92.577	ENSNGAG00000000191	-	100	92.577	Nannospalax_galili
ENSG00000142149	HUNK	100	99.020	ENSNLEG00000036238	HUNK	100	99.020	Nomascus_leucogenys
ENSG00000142149	HUNK	100	88.039	ENSOPRG00000009958	HUNK	100	87.761	Ochotona_princeps
ENSG00000142149	HUNK	100	91.748	ENSODEG00000002662	HUNK	100	91.748	Octodon_degus
ENSG00000142149	HUNK	90	93.793	ENSOCUG00000005096	HUNK	100	89.954	Oryctolagus_cuniculus
ENSG00000142149	HUNK	100	91.597	ENSOGAG00000010230	HUNK	100	91.597	Otolemur_garnettii
ENSG00000142149	HUNK	95	91.259	ENSOARG00000013875	HUNK	80	91.259	Ovis_aries
ENSG00000142149	HUNK	97	100.000	ENSPPAG00000032225	HUNK	98	97.866	Pan_paniscus
ENSG00000142149	HUNK	100	92.157	ENSPPRG00000022852	HUNK	100	92.157	Panthera_pardus
ENSG00000142149	HUNK	97	88.182	ENSPTIG00000021583	HUNK	99	90.938	Panthera_tigris_altaica
ENSG00000142149	HUNK	100	99.720	ENSPTRG00000013849	HUNK	100	99.720	Pan_troglodytes
ENSG00000142149	HUNK	100	99.020	ENSPANG00000022529	HUNK	100	99.020	Papio_anubis
ENSG00000142149	HUNK	90	84.828	ENSPKIG00000022484	HUNK	92	76.045	Paramormyrops_kingsleyae
ENSG00000142149	HUNK	89	90.278	ENSPSIG00000014236	HUNK	100	69.371	Pelodiscus_sinensis
ENSG00000142149	HUNK	98	92.275	ENSPEMG00000005678	Hunk	98	92.240	Peromyscus_maniculatus_bairdii
ENSG00000142149	HUNK	90	90.345	ENSPCIG00000014547	HUNK	100	75.829	Phascolarctos_cinereus
ENSG00000142149	HUNK	97	100.000	ENSPPYG00000011356	HUNK	100	93.417	Pongo_abelii
ENSG00000142149	HUNK	90	91.034	ENSPCAG00000001322	HUNK	100	79.787	Procavia_capensis
ENSG00000142149	HUNK	100	95.098	ENSPCOG00000007940	HUNK	100	95.098	Propithecus_coquereli
ENSG00000142149	HUNK	100	90.756	ENSPVAG00000005225	HUNK	100	90.756	Pteropus_vampyrus
ENSG00000142149	HUNK	100	92.157	ENSRNOG00000002092	Hunk	100	92.157	Rattus_norvegicus
ENSG00000142149	HUNK	97	100.000	ENSRBIG00000031500	HUNK	100	99.331	Rhinopithecus_bieti
ENSG00000142149	HUNK	99	98.457	ENSRROG00000037737	HUNK	99	98.457	Rhinopithecus_roxellana
ENSG00000142149	HUNK	97	94.495	ENSSBOG00000026563	HUNK	100	96.656	Saimiri_boliviensis_boliviensis
ENSG00000142149	HUNK	90	90.345	ENSSHAG00000009609	HUNK	99	76.341	Sarcophilus_harrisii
ENSG00000142149	HUNK	90	86.207	ENSSFOG00015006294	HUNK	90	52.087	Scleropages_formosus
ENSG00000142149	HUNK	90	90.345	ENSSPUG00000012338	HUNK	100	64.795	Sphenodon_punctatus
ENSG00000142149	HUNK	97	87.156	ENSSSCG00000029392	HUNK	92	94.030	Sus_scrofa
ENSG00000142149	HUNK	90	91.034	ENSTGUG00000013465	HUNK	100	72.117	Taeniopygia_guttata
ENSG00000142149	HUNK	60	98.969	ENSTTRG00000015604	-	64	99.200	Tursiops_truncatus
ENSG00000142149	HUNK	97	88.991	ENSUAMG00000027223	HUNK	97	91.228	Ursus_americanus
ENSG00000142149	HUNK	97	88.991	ENSUMAG00000017146	HUNK	98	91.011	Ursus_maritimus
ENSG00000142149	HUNK	82	99.248	ENSVPAG00000012399	-	68	99.379	Vicugna_pacos
ENSG00000142149	HUNK	97	89.908	ENSVVUG00000002915	HUNK	100	90.468	Vulpes_vulpes

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0004674	protein serine/threonine kinase activity	21873635.	IBA	Function
GO:0005515	protein binding	20133759.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0006468	protein phosphorylation	21873635.	IBA	Process
GO:0007165	signal transduction	10662544.	TAS	Process
GO:0007275	multicellular organism development	10662544.	TAS	Process
GO:0035556	intracellular signal transduction	21873635.	IBA	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

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Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.