Cancer | Chr | Position | Mutation Type | dbSNP | Protein-change | Allele Freq | RBD |
---|---|---|---|---|---|---|---|
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BRCA | |||||||
CESC | |||||||
CESC | |||||||
CESC | |||||||
CESC | |||||||
CESC | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
ESCA | |||||||
GBM | |||||||
GBM | |||||||
HNSC | |||||||
HNSC | |||||||
HNSC | |||||||
HNSC | |||||||
KIRC | |||||||
KIRC | |||||||
KIRC | |||||||
KIRC | |||||||
KIRP | |||||||
LGG | |||||||
LGG | |||||||
LIHC | |||||||
LUAD | |||||||
LUAD | |||||||
LUAD | |||||||
LUAD | |||||||
LUAD | |||||||
LUSC | |||||||
LUSC | |||||||
LUSC | |||||||
LUSC | |||||||
OV | |||||||
OV | |||||||
PAAD | |||||||
PRAD | |||||||
PRAD | |||||||
PRAD | |||||||
READ | |||||||
READ | |||||||
READ | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC |
Cancer | Type | Freq | Q-value |
---|---|---|---|
CESC | |||
KIRP | |||
LUSC | |||
OV | |||
PAAD | |||
TGCT | |||
UCEC |
Cancer | P-value | Q-value |
---|---|---|
SARC | ||
MESO | ||
ACC | ||
HNSC | ||
KIRP | ||
PAAD | ||
BLCA | ||
CESC | ||
LIHC | ||
LGG | ||
UVM | ||
OV |
Transcript ID | Name | Length | RefSeq ID | Protein ID | Length | RefSeq ID | UniportKB ID |
---|---|---|---|---|---|---|---|
ENST00000404371 | PDIA6-203 | 2682 | - | ENSP00000385385 | 492 (aa) | - | Q15084 |
ENST00000458536 | PDIA6-205 | 986 | - | ENSP00000389558 | 11 (aa) | - | C9JNG5 |
ENST00000272227 | PDIA6-201 | 2338 | XM_011510308 | ENSP00000272227 | 440 (aa) | XP_011508610 | Q15084 |
ENST00000404824 | PDIA6-204 | 2236 | - | ENSP00000384459 | 488 (aa) | - | Q15084 |
ENST00000540494 | PDIA6-207 | 2509 | - | ENSP00000438778 | 437 (aa) | - | Q15084 |
ENST00000489662 | PDIA6-206 | 564 | - | - | - (aa) | - | - |
ENST00000381611 | PDIA6-202 | 2534 | - | ENSP00000371024 | 445 (aa) | - | Q15084 |
ENST00000617249 | PDIA6-208 | 2344 | - | ENSP00000481892 | 492 (aa) | - | Q15084 |
Pathway ID | Pathway Name | Source |
---|---|---|
hsa04141 | Protein processing in endoplasmic reticulum | KEGG |
ensgID | Trait | pValue | Pubmed ID |
---|---|---|---|
ENSG00000143870 | Respiratory Function Tests | 3.83836072893993E-5 | 17903307 |
ENSG00000143870 | Osteoporosis | 8.81822629021922E-5 | 17903295 |
ENSG00000143870 | Platelet Function Tests | 9.0396738E-006 | - |
ENSG00000143870 | Education | 4E-8 | 27225129 |
ENSG00000143870 | Education | 3E-8 | 27225129 |
ENSG00000143870 | Eye Movements | 4E-6 | 26242244 |
ENSG00000143870 | Education | 2E-10 | 27225129 |
ensgID | SNP | Chromosome | Position | SNP-risk | Trait | PubmedID | 95% CI | Or or BEAT | EFO ID |
---|---|---|---|---|---|---|---|---|---|
ENSG00000143870 | rs7590368 | 2 | 10821348 | T | Educational attainment (years of education) | 27225129 | NR unit decrease | 0.013930134 | EFO_0004784 |
ENSG00000143870 | rs76076331 | 2 | 10837459 | T | Educational attainment (years of education) | 27225129 | NR unit increase | 0.02040167 | EFO_0004784 |
ENSG00000143870 | rs76076331 | 2 | 10837459 | T | Educational attainment (college completion) | 27225129 | [NR] | 1.0468786 | EFO_0004784 |
ENSG00000143870 | rs4669634 | 2 | 10836701 | A | Self-reported math ability | 30038396 | [0.01-0.018] unit decrease | 0.0142 | EFO_0004875 |
ENSG00000143870 | rs76076331 | 2 | 10837459 | T | Educational attainment (MTAG) | 30038396 | [0.016-0.024] unit increase | 0.0201 | EFO_0004784 |
ENSG00000143870 | rs11885932 | 2 | 10833075 | A | Highest math class taken | 30038396 | [0.015-0.031] unit decrease | 0.0231 | EFO_0004875 |
ENSG00000143870 | rs4669634 | 2 | 10836701 | A | Self-reported math ability (MTAG) | 30038396 | [0.012-0.019] unit decrease | 0.0157 | EFO_0004875 |
ENSG00000143870 | rs76076331 | 2 | 10837459 | T | Highest math class taken (MTAG) | 30038396 | [0.018-0.028] unit increase | 0.0228 | EFO_0004875 |
ENSG00000143870 | rs4669634 | 2 | 10836701 | A | Cognitive performance (MTAG) | 30038396 | [0.015-0.025] unit decrease | 0.0198 | EFO_0008354 |
ENSG00000143870 | rs116156133 | 2 | 10812522 | ? | General cognitive ability | 29844566 | z-score increase | 4.469 | EFO_0004337 |
ENSG00000143870 | rs7590368 | 2 | 10821348 | T | Educational attainment (years of education) | 30038396 | [0.011-0.018] unit decrease | 0.0146 | EFO_0004784 |
ENSG00000143870 | rs76076331 | 2 | 10837459 | T | Educational attainment (years of education) | 30038396 | [0.016-0.025] unit increase | 0.0206 | EFO_0004784 |
ENSG00000143870 | rs12474895 | 2 | 10817722 | ? | Educational attainment (years of education) | 30595370 | EFO_0004784 |
Ensembl ID | Gene Symbol | Coverage | Identiy | Ortholog | Gene Symbol | Coverage | Identiy | Species |
---|---|---|---|---|---|---|---|---|
ENSG00000143870 | PDIA6 | 96 | 53.488 | WBGene00015168 | pdi-6 | 99 | 54.649 | Caenorhabditis_elegans |
ENSG00000143870 | PDIA6 | 100 | 95.227 | ENSMUSG00000020571 | Pdia6 | 99 | 95.227 | Mus_musculus |
Go ID | Go_term | PubmedID | Evidence | Category |
---|---|---|---|---|
GO:0003756 | protein disulfide isomerase activity | - | IEA | Function |
GO:0005515 | protein binding | 15466936.21057456.21670307.24189400.30021884. | IPI | Function |
GO:0005615 | extracellular space | 19995400. | IDA | Component |
GO:0005783 | endoplasmic reticulum | - | IDA | Component |
GO:0005783 | endoplasmic reticulum | 16130169. | TAS | Component |
GO:0005788 | endoplasmic reticulum lumen | - | TAS | Component |
GO:0005789 | endoplasmic reticulum membrane | - | TAS | Component |
GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment | 15308636. | IDA | Component |
GO:0005829 | cytosol | - | IDA | Component |
GO:0005886 | plasma membrane | - | IEA | Component |
GO:0006457 | protein folding | 7590364. | TAS | Process |
GO:0015037 | peptide disulfide oxidoreductase activity | 16677074. | IDA | Function |
GO:0034663 | endoplasmic reticulum chaperone complex | - | ISS | Component |
GO:0036498 | IRE1-mediated unfolded protein response | - | TAS | Process |
GO:0042470 | melanosome | - | IEA | Component |
GO:0043687 | post-translational protein modification | - | TAS | Process |
GO:0044267 | cellular protein metabolic process | - | TAS | Process |
GO:0045454 | cell redox homeostasis | - | IEA | Process |
GO:0055114 | oxidation-reduction process | - | IEA | Process |
GO:0070062 | extracellular exosome | 20458337. | HDA | Component |