| PID | Title | Article | Time | Author | Doi |
|---|---|---|---|---|---|
| 16474133 | Inhibition of the ATM/p53 signal transduction pathway by Kaposi's sarcoma-associated herpesvirus interferon regulatory factor 1. | J Virol | 2006 Mar | Shin YC | - |
| 17393301 | The spectrum of ATM missense variants and their contribution to contralateral breast cancer. | Breast Cancer Res Treat | 2008 Jan | Broeks A | - |
| 25935535 | Low ATM protein expression in malignant tumor as well as cancer-associated stroma are independent prognostic factors in a retrospective study of early-stage hormone-negative breast cancer. | Breast Cancer Res | 2015 May 3 | Feng X | doi: 10.1186/s13058-015-0575-2. |
| 21102523 | Transforming growth factor-β regulates the sphere-initiating stem cell-like feature in breast cancer through miRNA-181 and ATM. | Oncogene | 2011 Mar 24 | Wang Y | doi: 10.1038/onc.2010.531 |
| 19029835 | PKCalpha activation downregulates ATM and radio-sensitizes androgen-sensitive human prostate cancer cells in vitro and in vivo. | Cancer Biol Ther | 2009 Jan | Truman JP | - |
| 16997395 | ATM activation is accompanied with earlier stages of prostate tumorigenesis. | Biochim Biophys Acta | 2006 Oct | Fan C | - |
| 27535224 | The Breast Cancer Tumor Suppressor TRIM29 Is Expressed via ATM-dependent Signaling in Response to Hypoxia. | J Biol Chem | 2016 Oct 7 | D??kel M | - |
| 27613518 | 53BP1 depletion causes PARP inhibitor resistance in ATM-deficient breast cancer cells. | BMC Cancer | 2016 Sep 9 | Hong R | doi: 10.1186/s12885-016-2754-7. |
| 27556690 | Ataxia-telangiectasia mutated activation mediates tumor necrosis factor-alpha induced MMP-13 up-regulation and metastasis in lung cancer cells. | Oncotarget | 2016 Sep 20 | Yan HQ | doi: 10.18632/oncotarget.11386. |
| 24324828 | Mutation at intronic repeats of the ataxia-telangiectasia mutated (ATM) gene and ATM protein loss in primary gastric cancer with microsatellite instability. | PLoS One | 2013 Dec 6 | Kim HS | doi: 10.1371/journal.pone.0082769 |
| 16329039 | ATM gene expression is associated with differentiation and angiogenesis in infiltrating breast carcinomas. | Histol Histopathol | 2006 Feb | Cuatrecasas M | doi: 10.14670/HH-21.149. |
| 21156285 | Loss of ATM/Chk2/p53 pathway components accelerates tumor development and contributes to radiation resistance in gliomas. | Cancer Cell | 2010 Dec 14 | Squatrito M | doi: 10.1016/j.ccr.2010.10.034. |
| 12032824 | Aberrant methylation of the ATM promoter correlates with increased radiosensitivity in a human colorectal tumor cell line. | Oncogene | 2002 May 30 | Kim WJ | - |
| 22923499 | Activation of the ATM-Snail pathway promotes breast cancer metastasis. | J Mol Cell Biol | 2012 Oct | Sun M | doi: 10.1093/jmcb/mjs048 |
| 24726882 | Induction of ATM/ATR pathway combined with Vγ2V??2 T cells enhances cytotoxicity of ovarian cancer cells. | Biochim Biophys Acta | 2014 Jul | Lu J | doi: 10.1016/j.bbadis.2014.04.003 |
| 20023412 | DNA damage signaling is activated during cancer progression in human colorectal carcinoma. | Cancer Biol Ther | 2010 Feb | Oka K | - |
| 26300260 | MacroH2A1 and ATM Play Opposing Roles in Paracrine Senescence and the Senescence-Associated Secretory Phenotype. | Mol Cell | 2015 Sep 3 | Chen H | doi: 10.1016/j.molcel.2015.07.011 |
| 22094875 | ATM-mediated DNA damage signals mediate immune escape through integrin-αvβ3-dependent mechanisms. | Cancer Res | 2012 Jan 1 | Jinushi M | doi: 10.1158/0008-5472.CAN-11-2028 |
| 26053094 | Ataxia-telangiectasia mutated (ATM) silencing promotes neuroblastoma progression through a MYCN independent mechanism. | Oncotarget | 2015 Jul 30 | Mandriota SJ | - |
| 11830610 | Dominant negative ATM mutations in breast cancer families. | J Natl Cancer Inst | 2002 Feb 6 | Chenevix-Trench G | - |
| 26220524 | Loss of ATM accelerates pancreatic cancer formation and epithelial-mesenchymal transition. | Nat Commun | 2015 Jul 29 | Russell R | doi: 10.1038/ncomms8677. |
| 18565893 | Risk of cancer by ATM missense mutations in the general population. | J Clin Oncol | 2008 Jun 20 | Dombernowsky SL | doi: 10.1200/JCO.2007.14.6613. |
| 12409306 | Identification of a novel protein kinase mediating Akt survival signaling to the ATM protein. | J Biol Chem | 2003 Jan 3 | Suzuki A | - |
| 23878245 | Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1. | Proc Natl Acad Sci U S A | 2013 Aug 6 | Tripathi DN | doi: 10.1073/pnas.1307736110 |
| 18343821 | Determination of three-dimensional structure and residues of the novel tumor suppressor AIMP3/p18 required for the interaction with ATM. | J Biol Chem | 2008 May 16 | Kim KJ | doi: 10.1074/jbc.M800859200 |
| 22951905 | Phospho-??Np63α/SREBF1 protein interactions: bridging cell metabolism and cisplatin chemoresistance. | Cell Cycle | 2012 Oct 15 | Huang Y | doi: 10.4161/cc.22022 |
| 16432227 | ATM promotes apoptosis and suppresses tumorigenesis in response to Myc. | Proc Natl Acad Sci U S A | 2006 Jan 31 | Pusapati RV | - |
| 26662178 | Health risks for ataxia-telangiectasia mutated heterozygotes: a systematic review, meta-analysis and evidence-based guideline. | Clin Genet | 2016 Aug | van Os NJ | doi: 10.1111/cge.12710 |
| 27959407 | Low-dose irradiation promotes proliferation of the human breast cancer MDA-MB-231 cells through accumulation of mutant P53. | Int J Oncol | 2017 Jan | Li SJ | doi: 10.3892/ijo.2016.3795 |
| 28691344 | Combined tumor genomic profiling and exome sequencing in a breast cancer family implicates ATM in tumorigenesis: A proof of principle study. | Genes Chromosomes Cancer | 2017 Nov | Bubien V | doi: 10.1002/gcc.22482 |
| 29115439 | Low-dose irradiation inhibits proliferation of the p53null type human prostate cancer cells through the ATM/p21 pathway. | Int J Mol Med | 2018 Jan | Li SJ | doi: 10.3892/ijmm.2017.3237 |
| 30562756 | ATM-Mediated Phosphorylation of Cortactin Involved in Actin Polymerization Promotes Breast Cancer Cells Migration and Invasion. | Cell Physiol Biochem | 2018 | Lang L | doi: 10.1159/000496048 |
| 16914028 | ATM variants and cancer risk in breast cancer patients from Southern Finland. | BMC Cancer | 2006 Aug 16 | Tommiska J | - |
| 27466510 | DNA Repair Gene Expression Levels as Indicators of Breast Cancer in the Breast Cancer Family Registry. | Anticancer Res | 2016 Aug | Kappil MA | - |
| 22276117 | The association between ATM IVS 22-77 T>C and cancer risk: a meta-analysis. | PLoS One | 2012 | Zhao L | doi: 10.1371/journal.pone.0029479 |
| 26506520 | Prevalence of deleterious ATM germline mutations in gastric cancer patients. | Oncotarget | 2015 Dec 1 | Huang DS | doi: 10.18632/oncotarget.5944. |
| 21187516 | Association between ataxia telangiectasia mutated gene polymorphisms and breast cancer in Taiwanese females. | Anticancer Res | 2010 Dec | Wang HC | - |
| 12612651 | ATM and related protein kinases: safeguarding genome integrity. | Nat Rev Cancer | 2003 Mar | Shiloh Y | - |
| 27542403 | MiR-203 inhibits tumor invasion and metastasis in gastric cancer by ATM. | Acta Biochim Biophys Sin (Shanghai) | 2016 Aug | Zhou P | doi: 10.1093/abbs/gmw063 |
| 17428325 | Common variants in the ATM, BRCA1, BRCA2, CHEK2 and TP53 cancer susceptibility genes are unlikely to increase breast cancer risk. | Breast Cancer Res | 2007 | Baynes C | - |
| 19153073 | Gene-body hypermethylation of ATM in peripheral blood DNA of bilateral breast cancer patients. | Hum Mol Genet | 2009 Apr 1 | Flanagan JM | doi: 10.1093/hmg/ddp033 |
| 21108427 | Association between DNA repair gene ATM polymorphisms and oral cancer susceptibility. | Laryngoscope | 2010 Dec | Bau DT | doi: 10.1002/lary.21009. |
| 12810666 | Contributions of ATM mutations to familial breast and ovarian cancer. | Cancer Res | 2003 Jun 15 | Thorstenson YR | - |
| 22323184 | The role of ATM and 53BP1 as predictive markers in cervical cancer. | Int J Cancer | 2012 Nov 1 | Roossink F | doi: 10.1002/ijc.27488 |
| 23649938 | Ataxia-telangiectasia-mutated protein expression with microsatellite instability in gastric cancer as prognostic marker. | Int J Cancer | 2014 Jan 1 | Kim JW | doi: 10.1002/ijc.28245 |
| 24023351 | Effects of ataxia telangiectasia mutated (ATM) genotypes and smoking habits on lung cancer risk in Taiwan. | Anticancer Res | 2013 Sep | Hsia TC | - |
| 27227554 | Effect of ATM-111 (G>A) Polymorphism on Cancer Risk: A Meta-Analysis. | Genet Test Mol Biomarkers | 2016 Jul | Huang S | doi: 10.1089/gtmb.2015.0320 |
| 28423511 | ATM kinase sustains breast cancer stem-like cells by promoting ATG4C expression and autophagy. | Oncotarget | 2017 Mar 28 | Antonelli M | doi: 10.18632/oncotarget.15537. |
| 27599564 | Detection of ATM germline variants by the p53 mitotic centrosomal localization test in BRCA1/2-negative patients with early-onset breast cancer. | J Exp Clin Cancer Res | 2016 Sep 6 | Prodosmo A | doi: 10.1186/s13046-016-0410-3. |
| 28453388 | Susceptibility of ATM-deficient pancreatic cancer cells to radiation. | Cell Cycle | 2017 May 19 | Ayars M | doi: 10.1080/15384101.2017.1312236 |
| 30128886 | GLTSCR1, ATM, PPP1R13L and CD3EAP Genetic Variants and Lung Cancer Risk in a Chinese Population. | Curr Med Sci | 2018 Aug | Yin JY | doi: 10.1007/s11596-018-1938-6 |
| 25541996 | Effect of single nucleotide polymorphism Rs189037 in ATM gene on risk of lung cancer in Chinese: a case-control study. | PLoS One | 2014 Dec 26 | Liu J | doi: 10.1371/journal.pone.0115845 |
| 25862169 | Oxidative stress shapes breast cancer phenotype through chronic activation of ATM-dependent signaling. | Breast Cancer Res Treat | 2015 May | Alpay M | doi: 10.1007/s10549-015-3368-5 |
| 17333338 | Screening for ATM sequence alterations in African-American women diagnosed with breast cancer. | Breast Cancer Res Treat | 2008 Jan | Hirsch AE | - |
| 20354815 | Genetic polymorphisms in ATM, ERCC1, APE1 and iASPP genes and lung cancer risk in a population of southeast China. | Med Oncol | 2011 Sep | Deng Q | doi: 10.1007/s12032-010-9507-2 |
| 23154512 | Loss of expression of the double strand break repair protein ATM is associated with worse prognosis in colorectal cancer and loss of Ku70 expression is associated with CIN. | Oncotarget | 2012 Nov | Beggs AD | - |
| 23925578 | Association of the ATM gene polymorphisms with papillary thyroid cancer. | Endocrine | 2014 Apr | Gu Y | doi: 10.1007/s12020-013-0020-1 |
| 19071090 | ATM is required for rapid degradation of cyclin D1 in response to gamma-irradiation. | Biochem Biophys Res Commun | 2009 Jan 23 | Choo DW | doi: 10.1016/j.bbrc.2008.11.132 |
| 15846060 | ATM activation in normal human tissues and testicular cancer. | Cell Cycle | 2005 Jun | Bartkova J | - |
| 19404735 | ATM germline mutations in women with familial breast cancer and a relative with haematological malignancy. | Breast Cancer Res Treat | 2010 Jan | Paglia LL | doi: 10.1007/s10549-009-0396-z |
| 25846551 | Profiling cancer gene mutations in longitudinal epithelial ovarian cancer biopsies by targeted next-generation sequencing: a retrospective study. | Ann Oncol | 2015 Jul | Beltrame L | doi: 10.1093/annonc/mdv164 |
| 19781682 | Rare, evolutionarily unlikely missense substitutions in ATM confer increased risk of breast cancer. | Am J Hum Genet | 2009 Oct | Tavtigian SV | doi: 10.1016/j.ajhg.2009.08.018 |
| 26778106 | The risk for developing cancer in Israeli ATM, BLM, and FANCC heterozygous mutation carriers. | Cancer Genet | 2016 Mar | Laitman Y | doi: 10.1016/j.cancergen.2015.12.006 |
| 11805335 | Missense mutations but not allelic variants alter the function of ATM by dominant interference in patients with breast cancer. | Proc Natl Acad Sci U S A | 2002 Jan 22 | Scott SP | - |
| 23776433 | Ataxia-telangiectasia group D complementing gene (ATDC) promotes lung cancer cell proliferation by activating NF-??B pathway. | PLoS One | 2013 Jun 12 | Tang ZP | doi: 10.1371/journal.pone.0063676 |
| 18433505 | Association of common ATM variants with familial breast cancer in a South American population. | BMC Cancer | 2008 Apr 23 | Gonz??lez-Hormaz??bal P | doi: 10.1186/1471-2407-8-117. |
| 22420423 | Low expression levels of ATM may substitute for CHEK2 /TP53 mutations predicting resistance towards anthracycline and mitomycin chemotherapy in breast cancer. | Breast Cancer Res | 2012 Mar 15 | Knappskog S | - |
| 23686257 | Genistein induces G2/M cell cycle arrest and apoptosis via ATM/p53-dependent pathway in human colon cancer cells. | Int J Oncol | 2013 Jul | Zhang Z | doi: 10.3892/ijo.2013.1946 |
| 21127011 | Lower ataxia telangiectasia mutated (ATM) mRNA expression is correlated with poor outcome of laryngeal and pharyngeal cancer patients. | Ann Oncol | 2011 May | Lee KW | doi: 10.1093/annonc/mdq569 |
| 22200742 | Genetic polymorphisms and cervical cancer development: ATM G5557A and p53bp1 C1236G. | Oncol Rep | 2012 Apr | Oliveira S | doi: 10.3892/or.2011.1609 |
| 15837784 | Down-regulation of ATM protein sensitizes human prostate cancer cells to radiation-induced apoptosis. | J Biol Chem | 2005 Jun 17 | Truman JP | - |
| 21445571 | Germline ATM mutational analysis in BRCA1/BRCA2 negative hereditary breast cancer families by MALDI-TOF mass spectrometry. | Breast Cancer Res Treat | 2011 Jul | Gra | doi: 10.1007/s10549-011-1462-x |
| 26098866 | Loss-of-function variants in ATM confer risk of gastric cancer. | Nat Genet | 2015 Aug | Helgason H | doi: 10.1038/ng.3342 |
| 21034966 | The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer. | Adv Cancer Res | 2010 | Smith J | doi: 10.1016/B978-0-12-380888-2.00003-0. |
| 20513533 | High incidence of mutations in BRCA1 and BRCA2 genes in ovarian cancer. | Bull Exp Biol Med | 2007 Jul | Smirnova TY | - |
| 23851489 | Functional interplay between the DNA-damage-response kinase ATM and ARF tumour suppressor protein in human cancer. | Nat Cell Biol | 2013 Aug | Velimezi G | doi: 10.1038/ncb2795 |
| 24480460 | Aurora-A controls cancer cell radio- and chemoresistance via ATM/Chk2-mediated DNA repair networks. | Biochim Biophys Acta | 2014 May | Sun H | doi: 10.1016/j.bbamcr.2014.01.019 |
| 16832357 | ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles. | Nat Genet | 2006 Aug | Renwick A | - |
| 15880680 | Two ATM variants and breast cancer risk. | Hum Mutat | 2005 Jun | Thompson D | - |
| 21935375 | The phenotypic radiation resistance of CD44+/CD24(-or low) breast cancer cells is mediated through the enhanced activation of ATM signaling. | PLoS One | 2011 | Yin H | doi: 10.1371/journal.pone.0024080 |
| 24285016 | ATM down-regulation is associated with poor prognosis in sporadic breast carcinomas. | Ann Oncol | 2014 Jan | Bueno RC | doi: 10.1093/annonc/mdt421 |
| 17164260 | Effect of ATM, CHEK2 and ERBB2 TAGSNPs and haplotypes on endometrial cancer risk. | Hum Mol Genet | 2007 Jan 15 | Einarsd??ttir K | - |
| 26625310 | Infiltrating mast cells increase prostate cancer chemotherapy and radiotherapy resistances via modulation of p38/p53/p21 and ATM signals. | Oncotarget | 2016 Jan 12 | Xie H | doi: 10.18632/oncotarget.6372. |
| 16636671 | Identification of an ataxia telangiectasia-mutated protein mediated surveillance system to regulate Bcl-2 overexpression. | Oncogene | 2006 Sep 14 | Zhang J | - |
| 16998505 | ATM and breast cancer susceptibility. | Oncogene | 2006 Sep 25 | Ahmed M | - |
| 23328638 | Concordance of ATM (ataxia telangiectasia mutated) immunohistochemistry between biopsy or metastatic tumor samples and primary tumors in gastric cancer patients. | Pathobiology | 2013 | Kim HS | doi: 10.1159/000346034 |
| 14983937 | ATM protein overexpression in prostate tumors: possible role in telomere maintenance. | Am J Clin Pathol | 2004 Feb | Ang??le S | - |
| 26030852 | ATM regulation of IL-8 links oxidative stress to cancer cell migration and invasion. | Elife | 2015 Jun 1 | Chen WT | doi: 10.7554/eLife.07270. |
| 24145123 | miR-203 induces oxaliplatin resistance in colorectal cancer cells by negatively regulating ATM kinase. | Mol Oncol | 2014 Feb | Zhou Y | doi: 10.1016/j.molonc.2013.09.004 |
| 24568192 | cAMP signaling inhibits radiation-induced ATM phosphorylation leading to the augmentation of apoptosis in human lung cancer cells. | Mol Cancer | 2014 Feb 24 | Cho EA | doi: 10.1186/1476-4598-13-36. |
| 20709753 | Selenium compounds activate ATM-dependent DNA damage response via the mismatch repair protein hMLH1 in colorectal cancer cells. | J Biol Chem | 2010 Oct 22 | Qi Y | doi: 10.1074/jbc.M110.137406 |
| 18642075 | Promoter methylation patterns of ATM, ATR, BRCA1, BRCA2 and p53 as putative cancer risk modifiers in Jewish BRCA1/BRCA2 mutation carriers. | Breast Cancer Res Treat | 2009 Jul | Kontorovich T | doi: 10.1007/s10549-008-0121-3 |
| 26517239 | The orally active and bioavailable ATR kinase inhibitor AZD6738 potentiates the anti-tumor effects of cisplatin to resolve ATM-deficient non-small cell lung cancer in vivo. | Oncotarget | 2015 Dec 29 | Vendetti FP | doi: 10.18632/oncotarget.6247. |
| 19723050 | Mechanism of beta-carotene-induced apoptosis of gastric cancer cells: involvement of ataxia-telangiectasia-mutated. | Ann N Y Acad Sci | 2009 Aug | Jang SH | doi: 10.1111/j.1749-6632.2009.04711.x. |
| 26851027 | ER-Dependent Ca++-mediated Cytosolic ROS as an Effector for Induction of Mitochondrial Apoptotic and ATM-JNK Signal Pathways in Gallic Acid-treated Human Oral Cancer Cells. | Anticancer Res | 2016 Feb | Lu YC | - |
| 21058196 | Antioxidant vitamins intake, ataxia telangiectasia mutated (ATM) genetic polymorphisms, and breast cancer risk. | Nutr Cancer | 2010 | Lee SA | doi: 10.1080/01635581.2010.492088. |
| 14553952 | ATM gene mutations are not involved in medulloblastoma in children. | Cancer Genet Cytogenet | 2003 Oct 15 | Liberzon E | - |
| 18557994 | Are the so-called low penetrance breast cancer genes, ATM, BRIP1, PALB2 and CHEK2, high risk for women with strong family histories? | Breast Cancer Res | 2008 | Byrnes GB | doi: 10.1186/bcr2099 |
| 24469230 | ATDC/TRIM29 phosphorylation by ATM/MAPKAP kinase 2 mediates radioresistance in pancreatic cancer cells. | Cancer Res | 2014 Mar 15 | Wang L | doi: 10.1158/0008-5472.CAN-13-2289 |
| 22203481 | Association between ATM polymorphisms and cancer risk: a meta-analysis. | Mol Biol Rep | 2012 May | Shen L | doi: 10.1007/s11033-011-1381-2 |
| 18497957 | Contribution of mutations in ATM to breast cancer development in the Czech population. | Oncol Rep | 2008 Jun | Soukupova J | - |
| 15928302 | Cancer risks and mortality in heterozygous ATM mutation carriers. | J Natl Cancer Inst | 2005 Jun 1 | Thompson D | - |
| 25014427 | ATM polymorphisms IVS24-9delT, IVS38-8T>C, and 5557G>A in Mexican women with familial and/or early-onset breast cancer. | Salud Publica Mex | 2014 Apr | Calder??n-Z?? | - |
| 20665102 | Association between polymorphisms of the ataxia telangiectasia mutated gene and breast cancer risk: evidence from the current studies. | Breast Cancer Res Treat | 2011 Feb | Lu PH | doi: 10.1007/s10549-010-1081-y |
| 11897822 | ATM mutations in Finnish breast cancer patients. | J Med Genet | 2002 Mar | Allinen M | - |
| 18701470 | Variants in the ATM gene associated with a reduced risk of contralateral breast cancer. | Cancer Res | 2008 Aug 15 | Concannon P | doi: 10.1158/0008-5472.CAN-08-0134. |
| 23681803 | Ataxia-telangiectasia group D complementing gene (ATDC) upregulates matrix metalloproteinase 9 (MMP-9) to promote lung cancer cell invasion by activating ERK and JNK pathways. | Tumour Biol | 2013 Oct | Tang ZP | doi: 10.1007/s13277-013-0843-7 |
| 22072393 | Gene-gene interactions in breast cancer susceptibility. | Hum Mol Genet | 2012 Feb 15 | Turnbull C | doi: 10.1093/hmg/ddr525 |
| 19401701 | Activation of ATM/Chk1 by curcumin causes cell cycle arrest and apoptosis in human pancreatic cancer cells. | Br J Cancer | 2009 May 5 | Sahu RP | doi: 10.1038/sj.bjc.6605039. |
| 17431766 | Two-stage case-control study of common ATM gene variants in relation to breast cancer risk. | Breast Cancer Res Treat | 2007 Nov | Ye C | - |
| 25970706 | Oxidized ATM promotes abnormal proliferation of breast CAFs through maintaining intracellular redox homeostasis and activating the PI3K-AKT, MEK-ERK, and Wnt-β-catenin signaling pathways. | Cell Cycle | 2015 | Tang S | doi: 10.1080/15384101.2015.1041685. |
| 20338046 | DNA methylation profiling in doxorubicin treated primary locally advanced breast tumours identifies novel genes associated with survival and treatment response. | Mol Cancer | 2010 Mar 25 | Dejeux E | doi: 10.1186/1476-4598-9-68. |
| 19302790 | ATM blocks tunicamycin-induced endoplasmic reticulum stress. | FEBS Lett | 2009 Mar 4 | He L | doi: 10.1016/j.febslet.2009.02.002 |
| 25425972 | Clinicopathological significance of ATM-Chk2 expression in sporadic breast cancers: a comprehensive analysis in large cohorts. | Neoplasia | 2014 Nov 20 | Abdel-Fatah TM | doi: 10.1016/j.neo.2014.09.009 |
| 12362033 | Constitutional alterations of the ATM gene in early onset sporadic breast cancer. | J Med Genet | 2002 Oct | Maillet P | - |
| 20004998 | ATM polymorphisms and risk of lung cancer among never smokers. | Lung Cancer | 2010 Aug | Lo YL | doi: 10.1016/j.lungcan.2009.11.007 |
| 17351744 | ATM allelic variants associated to hereditary breast cancer in 94 Chilean women: susceptibility or ethnic influences? | Breast Cancer Res Treat | 2008 Jan | Tapia T | - |
| 21787400 | Rare variants in the ATM gene and risk of breast cancer. | Breast Cancer Res | 2011 Jul 25 | Goldgar DE | doi: 10.1186/bcr2919. |
| 19028473 | Kaempferol induces apoptosis in human HCT116 colon cancer cells via the Ataxia-Telangiectasia Mutated-p53 pathway with the involvement of p53 Upregulated Modulator of Apoptosis. | Chem Biol Interact | 2009 Jan 27 | Li W | doi: 10.1016/j.cbi.2008.10.048 |
| 16533773 | Expression of DNA double-strand break repair proteins ATM and BRCA1 predicts survival in colorectal cancer. | Clin Cancer Res | 2006 Mar 1 | Grabsch H | - |
| 26825989 | Enhanced gefitinib-induced repression of the epidermal growth factor receptor pathway by ataxia telangiectasia-mutated kinase inhibition in non-small-cell lung cancer cells. | Cancer Sci | 2016 Apr | Misumi K | doi: 10.1111/cas.12899 |
| 22374981 | Intragenic ATM methylation in peripheral blood DNA as a biomarker of breast cancer risk. | Cancer Res | 2012 May 1 | Brennan K | doi: 10.1158/0008-5472.CAN-11-3157 |
| 21603857 | Association between ATM 5557G>A polymorphism and breast cancer risk: a meta-analysis. | Mol Biol Rep | 2012 Feb | Mao C | doi: 10.1007/s11033-011-0839-6 |
| 17166884 | Evaluation of the role of Finnish ataxia-telangiectasia mutations in hereditary predisposition to breast cancer. | Carcinogenesis | 2007 May | Pylk | - |
| 15390180 | Cancer risk according to type and location of ATM mutation in ataxia-telangiectasia families. | Genes Chromosomes Cancer | 2005 Jan | Cavaciuti E | - |
| 23857602 | Estrogen receptor α regulates ATM Expression through miRNAs in breast cancer. | Clin Cancer Res | 2013 Sep 15 | Guo X | doi: 10.1158/1078-0432.CCR-12-3700 |
| 18164969 | Detection of ATM gene mutations in young lung cancer patients: a population-based control study. | Arch Med Res | 2008 Feb | Schneider J | doi: 10.1016/j.arcmed.2007.08.004 |
| 23561644 | Exome sequencing identifies nonsegregating nonsense ATM and PALB2 variants in familial pancreatic cancer. | Hum Genomics | 2013 Apr 5 | Grant RC | doi: 10.1186/1479-7364-7-11. |
| 12072552 | Re: Dominant negative ATM mutations in breast cancer families. | J Natl Cancer Inst | 2002 Jun 19 | Lei H | - |
| 17001622 | Characterization of the breast cancer associated ATM 7271T>G (V2424G) mutation by gene expression profiling. | Genes Chromosomes Cancer | 2006 Dec | Waddell N | - |
| 20799949 | The association between ATM D1853N polymorphism and breast cancer susceptibility: a meta-analysis. | J Exp Clin Cancer Res | 2010 Aug 27 | Gao LB | doi: 10.1186/1756-9966-29-117. |
| 26505164 | Elevated Expression of Hepatoma Up-Regulated Protein Inhibits γ-Irradiation-Induced Apoptosis of Prostate Cancer Cells. | J Cell Biochem | 2016 Jun | Hassan M | doi: 10.1002/jcb.25419 |
| 25849217 | Common variants at 9q22.33, 14q13.3, and ATM loci, and risk of differentiated thyroid cancer in the French Polynesian population. | PLoS One | 2015 Apr 7 | Maillard S | doi: 10.1371/journal.pone.0123700 |
| 11830600 | Consortium piecing together role of ATM gene in breast cancer. | J Natl Cancer Inst | 2002 Feb 6 | Finkel E | - |
| 20177704 | From the set-up of a screening program of breast cancer patients to the identification of the first BRCA mutation in the DR Congo. | BMC Public Health | 2014 Jul 28 | Luyeye Mvila G | doi: 10.1186/1471-2458-14-759. |
| 25069040 | The role of oxidized ATM in the regulation of oxidative stress-induced energy metabolism reprogramming of CAFs. | Cancer Lett | 2014 Oct 28 | Tang S | doi: 10.1016/j.canlet.2014.07.028 |
| 25881002 | ATM kinase sustains HER2 tumorigenicity in breast cancer. | Nat Commun | 2015 Apr 16 | Stagni V | doi: 10.1038/ncomms7886. |
| 18634022 | Functional and computational assessment of missense variants in the ataxia-telangiectasia mutated (ATM) gene: mutations with increased cancer risk. | Hum Mutat | 2009 Jan | Mitui M | doi: 10.1002/humu.20805. |
| 17510082 | Aspirin blocks proliferation in colon cells by inducing a G1 arrest and apoptosis through activation of the checkpoint kinase ATM. | Carcinogenesis | 2007 Oct | Luciani MG | - |
| 19661334 | A common 9 bp deletion in the ataxia-telangiectasia-mutated gene is not associated with oral cancer. | Anticancer Res | 2009 Aug | Spyridonidou S | - |
| 24553124 | ATM controls proper mitotic spindle structure. | Cell Cycle | 2014 | Palazzo L | doi: 10.4161/cc.27945 |
| 20544271 | Lack of association between ATM C.1066-6T > G mutation and breast cancer risk: a meta-analysis of 8,831 cases and 4,957 controls. | Breast Cancer Res Treat | 2011 Jan | Ding H | doi: 10.1007/s10549-010-0977-x |
| 16652348 | The ATM missense mutation p.Ser49Cys (c.146C>G) and the risk of breast cancer. | Hum Mutat | 2006 Jun | Stredrick DL | - |
| 11996792 | Elevated frequency of ATM gene missense mutations in breast cancer relative to ethnically matched controls. | Cancer Genet Cytogenet | 2002 Apr 1 | Sommer SS | - |
| 25247188 | Multifunctional role of ATM/Tel1 kinase in genome stability: from the DNA damage response to telomere maintenance. | Biomed Res Int | 2014 | Di Domenico EG | doi: 10.1155/2014/787404 |
| 18807267 | A nonsense mutation (E1978X) in the ATM gene is associated with breast cancer. | Breast Cancer Res Treat | 2009 Nov | Bogdanova N | doi: 10.1007/s10549-008-0189-9 |
| 24486587 | Having pancreatic cancer with tumoral loss of ATM and normal TP53 protein expression is associated with a poorer prognosis. | Clin Cancer Res | 2014 Apr 1 | Kim H | doi: 10.1158/1078-0432.CCR-13-1239 |
| 24252502 | ATM-depletion in breast cancer cells confers sensitivity to PARP inhibition. | J Exp Clin Cancer Res | 2013 Nov 19 | Gilardini Montani MS | doi: 10.1186/1756-9966-32-95. |
| 18264724 | Single nucleotide polymorphism D1853N of the ATM gene may alter the risk for breast cancer. | J Cancer Res Clin Oncol | 2008 Aug | Schrauder M | doi: 10.1007/s00432-008-0355-9 |
| 17517479 | Possession of ATM sequence variants as predictor for late normal tissue responses in breast cancer patients treated with radiotherapy. | Int J Radiat Oncol Biol Phys | 2007 Nov 1 | Ho AY | - |
| 27918549 | A hypoxia-responsive TRAF6-ATM-H2AX signalling axis promotes HIF1α activation, tumorigenesis and | Nat Cell Biol | 2017 Jan | Rezaeian AH | doi: 10.1038/ncb3445 |
| 28259977 | miR-30a radiosensitizes non-small cell lung cancer by targeting ATF1 that is involved in the phosphorylation of ATM. | Oncol Rep | 2017 Apr | Guo Y | doi: 10.3892/or.2017.5448 |
| 27112364 | Penetrance of ATM Gene Mutations in Breast Cancer: A Meta-Analysis of Different Measures of Risk. | Genet Epidemiol | 2016 Jul | Marabelli M | doi: 10.1002/gepi.21971 |
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| 28418444 | Associations Between Cancer Predisposition Testing Panel Genes and Breast Cancer. | JAMA Oncol | 2017 Sep 1 | Couch FJ | doi: 10.1001/jamaoncol.2017.0424. |
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| 27913932 | Almost 2% of Spanish breast cancer families are associated to germline pathogenic mutations in the ATM gene. | Breast Cancer Res Treat | 2017 Feb | Tavera-Tapia A | doi: 10.1007/s10549-016-4058-7 |
| 27317574 | DNA Repair Deficiency Is Common in Advanced Prostate Cancer: New Therapeutic Opportunities. | Oncologist | 2016 Aug | Dhawan M | doi: 10.1634/theoncologist.2016-0135 |
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| Cancer | Chr | Position | Mutation Type | dbSNP | Protein-change | Allele Freq | RBD |
|---|---|---|---|---|---|---|---|
| ACC | chr11 | 108365322 | Splice_Region | novel | 0.23 | ||
| ACC | chr11 | 108252900 | Frame_Shift_Del | novel | S629Tfs*20 | 0.37 | |
| ACC | chr11 | 108267329 | Silent | novel | S875S | 0.2 | |
| ACC | chr11 | 108271359 | Frame_Shift_Del | novel | T1011Kfs*7 | 0.89 | |
| ACC | chr11 | 108365417 | Missense_Mutation | novel | S3027I | 0.61 | |
| ACC | chr11 | 108227691 | Nonsense_Mutation | rs746235533 | R23* | 0.92 | |
| BLCA | chr11 | 108249059 | Missense_Mutation | novel | D398H | 0.1 | |
| BLCA | chr11 | 108257514 | Missense_Mutation | novel | L762V | 0.3 | |
| BLCA | chr11 | 108284226 | Splice_Site | rs730881364 | X1249_splice | 0.77 | |
| BLCA | chr11 | 108304801 | Nonsense_Mutation | rs376603775 | R1875* | 0.44 | |
| BLCA | chr11 | 108244976 | Missense_Mutation | novel | Q284P | 0.53 | |
| BLCA | chr11 | 108244076 | Missense_Mutation | NA | S207C | 0.37 | |
| BLCA | chr11 | 108244900 | Missense_Mutation | NA | L259F | 0.05 | |
| BLCA | chr11 | 108271401 | Frame_Shift_Ins | NA | W1026Lfs*22 | 0.13 | |
| BLCA | chr11 | 108327644 | Splice_Site | novel | X2326_splice | 0.78 | |
| BLCA | chr11 | 108299821 | Missense_Mutation | novel | D1705N | 0.19 | |
| BLCA | chr11 | 108251902 | Missense_Mutation | NA | G558V | 0.16 | |
| BLCA | chr11 | 108330288 | Missense_Mutation | novel | R2461P | 0.19 | |
| BLCA | chr11 | 108327745 | Missense_Mutation | novel | T2359N | 0.27 | |
| BLCA | chr11 | 108257571 | Nonsense_Mutation | novel | Q781* | 0.56 | |
| BLCA | chr11 | 108301760 | Missense_Mutation | novel | L1764I | 0.59 | |
| BLCA | chr11 | 108365149 | Missense_Mutation | novel | R2973T | 0.32 | |
| BLCA | chr11 | 108229239 | Missense_Mutation | novel | S83A | 0.1 | |
| BLCA | chr11 | 108247012 | Missense_Mutation | NA | D317G | 0.38 | |
| BLCA | chr11 | 108325398 | Nonsense_Mutation | novel | E2221* | 0.32 | |
| BLCA | chr11 | 108335096 | Missense_Mutation | NA | R2713K | 0.06 | |
| BLCA | chr11 | 108281093 | Silent | novel | I1167I | 0.57 | |
| BLCA | chr11 | 108282770 | Missense_Mutation | novel | H1213N | 0.42 | |
| BLCA | chr11 | 108331951 | Missense_Mutation | novel | R2568G | 0.59 | |
| BLCA | chr11 | 108247048 | Missense_Mutation | novel | R329T | 0.44 | |
| BLCA | chr11 | 108235756 | Missense_Mutation | rs55633650 | D140H | 0.49 | |
| BLCA | chr11 | 108347356 | Missense_Mutation | NA | I2888L | 0.39 | |
| BLCA | chr11 | 108244873 | Nonsense_Mutation | rs772821016 | R250* | 0.57 | |
| BLCA | chr11 | 108251032 | Missense_Mutation | novel | F523V | 0.51 | |
| BLCA | chr11 | 108287645 | Missense_Mutation | novel | L1347V | 0.46 | |
| BLCA | chr11 | 108315829 | Missense_Mutation | novel | L2005I | 0.39 | |
| BLCA | chr11 | 108289732 | Missense_Mutation | NA | G1456D | 0.19 | |
| BLCA | chr11 | 108249075 | Nonsense_Mutation | novel | S403* | 0.37 | |
| BLCA | chr11 | 108295056 | Nonsense_Mutation | novel | Q1636* | 0.35 | |
| BLCA | chr11 | 108347359 | Missense_Mutation | rs587781814 | D2889H | 0.42 | |
| BLCA | chr11 | 108310236 | Missense_Mutation | novel | S1947P | 0.27 | |
| BLCA | chr11 | 108304693 | Nonsense_Mutation | rs786204751 | Q1839* | 0.4 | |
| BLCA | chr11 | 108316030 | Missense_Mutation | NA | E2039K | 0.2 | |
| BLCA | chr11 | 108251897 | Silent | NA | K556K | 0.45 | |
| BLCA | chr11 | 108326185 | In_Frame_Del | novel | Q2314_K2317del | 0.2 | |
| BLCA | chr11 | 108321339 | Missense_Mutation | novel | E2164G | 0.11 | |
| BLCA | chr11 | 108365147 | Missense_Mutation | novel | Q2972H | 0.43 | |
| BLCA | chr11 | 108282880 | Splice_Site | novel | X1249_splice | 0.27 | |
| BLCA | chr11 | 108304693 | Nonsense_Mutation | rs786204751 | Q1839* | 1 | |
| BLCA | chr11 | 108335871 | Silent | NA | A2726A | 0.5 | |
| BLCA | chr11 | 108333885 | Splice_Site | novel | X2643_splice | 0.71 | |
| BLCA | chr11 | 108284306 | Nonsense_Mutation | novel | Q1276* | 0.35 | |
| BLCA | chr11 | 108289761 | Nonsense_Mutation | rs730881369 | R1466* | 0.42 | |
| BLCA | chr11 | 108247072 | Missense_Mutation | rs202160435 | R337H | 0.44 | |
| BLCA | chr11 | 108267234 | Missense_Mutation | novel | G844R | 0.41 | |
| BLCA | chr11 | 108289667 | Silent | novel | K1434K | 0.96 | |
| BLCA | chr11 | 108347344 | Missense_Mutation | novel | E2884Q | 0.29 | |
| BLCA | chr11 | 108321338 | Missense_Mutation | NA | E2164Q | 0.19 | |
| BLCA | chr11 | 108326064 | Nonsense_Mutation | novel | E2272* | 0.24 | |
| BLCA | chr11 | 108317454 | Missense_Mutation | NA | E2094K | 0.21 | |
| BLCA | chr11 | 108321338 | Missense_Mutation | NA | E2164Q | 0.12 | |
| BLCA | chr11 | 108304797 | Silent | NA | C1873C | 0.34 | |
| BLCA | chr11 | 108282755 | Missense_Mutation | novel | D1208N | 0.23 | |
| BLCA | chr11 | 108316027 | Missense_Mutation | novel | H2038N | 0.83 | |
| BLCA | chr11 | 108235810 | Missense_Mutation | NA | E158Q | 0.75 | |
| BLCA | chr11 | 108325309 | Splice_Site | NA | X2191_splice | 0.75 | |
| BLCA | chr11 | 108247029 | Missense_Mutation | rs587781511 | I323V | 0.1 | |
| BLCA | chr11 | 108365337 | Missense_Mutation | NA | Q3000H | 0.23 | |
| BLCA | chr11 | 108365356 | Missense_Mutation | NA | E3007K | 0.25 | |
| BLCA | chr11 | 108365401 | Nonsense_Mutation | NA | E3022* | 0.27 | |
| BLCA | chr11 | 108267291 | Missense_Mutation | novel | D863N | 0.33 | |
| BLCA | chr11 | 108271273 | Missense_Mutation | rs587779830 | R982C | 0.47 | |
| BLCA | chr11 | 108335096 | Missense_Mutation | NA | R2713K | 0.56 | |
| BLCA | chr11 | 108329045 | Missense_Mutation | novel | D2372N | 0.23 | |
| BRCA | chr11 | 108299785 | Missense_Mutation | NA | D1693N | 0.44 | |
| BRCA | chr11 | 108365592 | 3'UTR | novel | 0.09 | ||
| BRCA | chr11 | 108289784 | Splice_Site | novel | X1474_splice | 0.6 | |
| BRCA | chr11 | 108310284 | Missense_Mutation | novel | D1963Y | 0.09 | |
| BRCA | chr11 | 108347318 | Missense_Mutation | rs587782451 | N2875S | 0.65 | |
| BRCA | chr11 | 108295300 | Intron | novel | 0.12 | ||
| BRCA | chr11 | 108258996 | Missense_Mutation | NA | N796T | 0.29 | |
| BRCA | chr11 | 108316010 | Splice_Site | NA | X2032_splice | 0.26 | |
| BRCA | chr11 | 108365208 | Nonsense_Mutation | rs770641163 | R2993* | 0.37 | |
| BRCA | chr11 | 108253839 | Missense_Mutation | NA | E642K | 0.73 | |
| BRCA | chr11 | 108253898 | Frame_Shift_Ins | NA | L663Ffs*42 | 0.19 | |
| BRCA | chr11 | 108330271 | Silent | NA | L2455L | 0.15 | |
| BRCA | chr11 | 108335851 | Missense_Mutation | NA | D2720N | 0.14 | |
| BRCA | chr11 | 108343292 | Missense_Mutation | NA | L2780R | 0.54 | |
| BRCA | chr11 | 108365476 | Nonsense_Mutation | rs121434219 | R3047* | 0.41 | |
| BRCA | chr11 | 108367706 | 3'UTR | novel | 0.24 | ||
| BRCA | chr11 | 108250827 | Silent | novel | Y454Y | 0.05 | |
| BRCA | chr11 | 108287573 | Intron | novel | 0.33 | ||
| BRCA | chr11 | 108365208 | Nonsense_Mutation | rs770641163 | R2993* | 0.64 | |
| BRCA | chr11 | 108312485 | Missense_Mutation | NA | G1998E | 0.47 | |
| BRCA | chr11 | 108333935 | Silent | novel | L2659L | 0.1 | |
| BRCA | chr11 | 108330234 | Missense_Mutation | rs587782310 | R2443Q | 0.81 | |
| BRCA | chr11 | 108325542 | Nonsense_Mutation | NA | Q2269* | 0.4 | |
| BRCA | chr11 | 108256236 | Missense_Mutation | NA | V716L | 0.85 | |
| BRCA | chr11 | 108229307 | Silent | NA | I105I | 0.21 | |
| BRCA | chr11 | 108249001 | Missense_Mutation | NA | S378R | 0.28 | |
| BRCA | chr11 | 108330216 | Missense_Mutation | NA | Y2437C | 0.16 | |
| BRCA | chr11 | 108302954 | Silent | NA | K1807K | 0.05 | |
| BRCA | chr11 | 108293460 | Missense_Mutation | novel | P1587T | 0.08 | |
| BRCA | chr11 | 108289078 | Missense_Mutation | novel | I1404S | 0.16 | |
| BRCA | chr11 | 108343351 | Nonsense_Mutation | novel | Q2800* | 0.04 | |
| BRCA | chr11 | 108256302 | Missense_Mutation | NA | E738K | 0.05 | |
| BRCA | chr11 | 108250761 | Silent | NA | L432L | 0.32 | |
| CESC | chr11 | 108252908 | Missense_Mutation | NA | E632K | 0.21 | |
| CESC | chr11 | 108259008 | Missense_Mutation | NA | S800F | 0.51 | |
| CESC | chr11 | 108279581 | Missense_Mutation | novel | L1125F | 0.29 | |
| CESC | chr11 | 108282815 | Missense_Mutation | NA | E1228K | 0.18 | |
| CESC | chr11 | 108292758 | Frame_Shift_Ins | novel | P1526Lfs*5 | 0.06 | |
| CESC | chr11 | 108335859 | Silent | novel | L2722L | 0.1 | |
| CESC | chr11 | 108289675 | Missense_Mutation | NA | R1437K | 0.44 | |
| CESC | chr11 | 108245000 | Missense_Mutation | rs747727055 | P292L | 0.43 | |
| CESC | chr11 | 108251846 | Silent | novel | V539V | 0.32 | |
| CESC | chr11 | 108267314 | Silent | rs587780618 | N870N | 0.33 | |
| CESC | chr11 | 108365529 | 3'UTR | novel | 0.45 | ||
| CESC | chr11 | 108307977 | Nonsense_Mutation | NA | Q1919* | 0.21 | |
| CESC | chr11 | 108294947 | Frame_Shift_Del | novel | S1601Ffs*7 | 0.48 | |
| CESC | chr11 | 108252018 | Missense_Mutation | NA | P597A | 0.11 | |
| CESC | chr11 | 108329187 | Missense_Mutation | NA | R2419T | 0.86 | |
| CESC | chr11 | 108367902 | 3'UTR | novel | 0.45 | ||
| CHOL | chr11 | 108250966 | Missense_Mutation | novel | Q501K | 0.67 | |
| CHOL | chr11 | 108252902 | Missense_Mutation | novel | V630L | 0.09 | |
| COAD | chr11 | 108247071 | Missense_Mutation | rs138398778 | R337C | 0.36 | |
| COAD | chr11 | 108293437 | Frame_Shift_Del | NA | I1581Sfs*20 | 0.25 | |
| COAD | chr11 | 108326173 | Missense_Mutation | novel | A2308V | 0.13 | |
| COAD | chr11 | 108259022 | Nonsense_Mutation | rs780619951 | R805* | 0.65 | |
| COAD | chr11 | 108244873 | Nonsense_Mutation | rs772821016 | R250* | 0.27 | |
| COAD | chr11 | 108297373 | Nonsense_Mutation | NA | E1666* | 0.26 | |
| COAD | chr11 | 108327726 | Missense_Mutation | NA | P2353T | 0.32 | |
| COAD | chr11 | 108247071 | Missense_Mutation | rs138398778 | R337C | 0.26 | |
| COAD | chr11 | 108310311 | Frame_Shift_Del | NA | R1973Efs*17 | 0.26 | |
| COAD | chr11 | 108245022 | Missense_Mutation | novel | E299D | 0.17 | |
| COAD | chr11 | 108325378 | Missense_Mutation | novel | D2214G | 0.13 | |
| COAD | chr11 | 108332766 | Missense_Mutation | rs140263969 | R2598Q | 0.21 | |
| COAD | chr11 | 108259073 | Missense_Mutation | novel | L822V | 0.21 | |
| COAD | chr11 | 108295089 | Intron | novel | 0.21 | ||
| COAD | chr11 | 108334984 | Nonsense_Mutation | novel | E2676* | 0.24 | |
| COAD | chr11 | 108259022 | Nonsense_Mutation | rs780619951 | R805* | 0.43 | |
| COAD | chr11 | 108251987 | Missense_Mutation | NA | E586D | 0.17 | |
| COAD | chr11 | 108247071 | Missense_Mutation | rs138398778 | R337C | 0.29 | |
| COAD | chr11 | 108294937 | Missense_Mutation | novel | H1596P | 0.06 | |
| COAD | chr11 | 108301790 | Splice_Site | novel | X1773_splice | 0.86 | |
| COAD | chr11 | 108284225 | Splice_Site | novel | X1249_splice | 0.39 | |
| COAD | chr11 | 108301647 | Splice_Site | novel | X1726_splice | 0.39 | |
| COAD | chr11 | 108329236 | Missense_Mutation | NA | N2435K | 0.38 | |
| COAD | chr11 | 108247072 | Missense_Mutation | rs202160435 | R337H | 0.37 | |
| COAD | chr11 | 108330216 | Missense_Mutation | NA | Y2437C | 0.33 | |
| COAD | chr11 | 108289697 | Frame_Shift_Ins | NA | V1446Cfs*2 | 0.25 | |
| COAD | chr11 | 108310270 | Missense_Mutation | NA | A1958V | 0.31 | |
| COAD | chr11 | 108247083 | Missense_Mutation | rs200601781 | V341I | 0.04 | |
| COAD | chr11 | 108252889 | Frame_Shift_Del | novel | F627Sfs*22 | 0.4 | |
| COAD | chr11 | 108245000 | Missense_Mutation | rs747727055 | P292L | 0.7 | |
| COAD | chr11 | 108327731 | Silent | novel | A2354A | 0.07 | |
| COAD | chr11 | 108347309 | Missense_Mutation | novel | H2872R | 0.36 | |
| COAD | chr11 | 108353856 | Missense_Mutation | rs730881329 | T2921M | 0.45 | |
| COAD | chr11 | 108335854 | Missense_Mutation | novel | D2721N | 0.35 | |
| COAD | chr11 | 108289075 | Missense_Mutation | novel | S1403N | 0.09 | |
| COAD | chr11 | 108345750 | Frame_Shift_Del | rs759472682 | K2811Sfs*46 | 0.34 | |
| COAD | chr11 | 108244090 | Frame_Shift_Del | NA | S214Pfs*16 | 0.39 | |
| COAD | chr11 | 108289008 | Missense_Mutation | novel | F1381L | 0.04 | |
| COAD | chr11 | 108292648 | Missense_Mutation | rs201594549 | R1489H | 0.38 | |
| COAD | chr11 | 108227882 | Frame_Shift_Del | NA | F61Lfs*15 | 0.54 | |
| COAD | chr11 | 108343260 | Nonsense_Mutation | rs778269655 | W2769* | 0.4 | |
| COAD | chr11 | 108330233 | Nonsense_Mutation | rs121434220 | R2443* | 0.37 | |
| COAD | chr11 | 108326153 | Frame_Shift_Del | novel | K2303Rfs*7 | 0.12 | |
| COAD | chr11 | 108267314 | Silent | rs587780618 | N870N | 0.18 | |
| COAD | chr11 | 108281098 | Frame_Shift_Del | NA | K1170Nfs*11 | 0.26 | |
| COAD | chr11 | 108335921 | Missense_Mutation | rs730881321 | T2743M | 0.24 | |
| COAD | chr11 | 108254037 | Nonsense_Mutation | novel | E708* | 0.44 | |
| COAD | chr11 | 108293438 | Missense_Mutation | novel | Q1579H | 0.23 | |
| COAD | chr11 | 108250960 | Missense_Mutation | NA | Q499E | 0.47 | |
| COAD | chr11 | 108297299 | Frame_Shift_Ins | novel | G1642Wfs*23 | 0.78 | |
| COAD | chr11 | 108271399 | Missense_Mutation | novel | A1024T | 0.3 | |
| COAD | chr11 | 108316029 | Silent | rs774993357 | H2038H | 0.32 | |
| COAD | chr11 | 108325426 | Frame_Shift_Del | NA | L2231Wfs*4 | 0.52 | |
| COAD | chr11 | 108304687 | Frame_Shift_Del | novel | C1838Vfs*8 | 0.42 | |
| COAD | chr11 | 108271401 | Frame_Shift_Ins | NA | W1026Lfs*22 | 0.36 | |
| COAD | chr11 | 108292698 | Missense_Mutation | novel | V1506M | 0.2 | |
| COAD | chr11 | 108244873 | Nonsense_Mutation | rs772821016 | R250* | 0.24 | |
| COAD | chr11 | 108252848 | Missense_Mutation | rs747242300 | L612I | 0.11 | |
| COAD | chr11 | 108295002 | Nonsense_Mutation | rs762083530 | R1618* | 0.1 | |
| COAD | chr11 | 108271274 | Missense_Mutation | novel | R982L | 0.12 | |
| COAD | chr11 | 108244120 | Splice_Site | NA | X221_splice | 0.34 | |
| COAD | chr11 | 108250942 | Missense_Mutation | rs750280306 | R493C | 0.36 | |
| COAD | chr11 | 108282874 | Missense_Mutation | NA | F1247L | 0.4 | |
| COAD | chr11 | 108304801 | Nonsense_Mutation | rs376603775 | R1875* | 0.32 | |
| COAD | chr11 | 108302997 | Nonsense_Mutation | NA | E1822* | 0.7 | |
| COAD | chr11 | 108299878 | Missense_Mutation | novel | E1724Q | 0.27 | |
| COAD | chr11 | 108271273 | Missense_Mutation | rs587779830 | R982C | 0.27 | |
| COAD | chr11 | 108247071 | Missense_Mutation | rs138398778 | R337C | 0.37 | |
| COAD | chr11 | 108326153 | Frame_Shift_Del | novel | K2303Rfs*7 | 0.37 | |
| COAD | chr11 | 108284473 | Splice_Region | NA | Q1331Q | 0.18 | |
| COAD | chr11 | 108251903 | Silent | NA | G558G | 0.33 | |
| COAD | chr11 | 108329220 | Missense_Mutation | rs786202856 | H2430R | 0.3 | |
| COAD | chr11 | 108250896 | Missense_Mutation | NA | K477N | 0.17 | |
| COAD | chr11 | 108301658 | Nonsense_Mutation | rs764389018 | R1730* | 0.29 | |
| COAD | chr11 | 108317403 | Missense_Mutation | NA | L2077I | 0.19 | |
| COAD | chr11 | 108315825 | Missense_Mutation | NA | D2003E | 0.12 | |
| COAD | chr11 | 108293459 | Frame_Shift_Del | novel | P1587Ffs*13 | 0.08 | |
| COAD | chr11 | 108329168 | Frame_Shift_Ins | novel | K2413Tfs*11 | 0.06 | |
| COAD | chr11 | 108335026 | In_Frame_Ins | novel | F2690delinsYII | 0.12 | |
| COAD | chr11 | 108316015 | Nonsense_Mutation | rs532480170 | R2034* | 0.21 | |
| COAD | chr11 | 108297025 | Intron | novel | 0.5 | ||
| COAD | chr11 | 108310315 | Missense_Mutation | NA | R1973I | 0.37 | |
| COAD | chr11 | 108365426 | Missense_Mutation | NA | G3030V | 0.23 | |
| COAD | chr11 | 108294972 | Frame_Shift_Ins | novel | T1609* | 0.23 | |
| COAD | chr11 | 108329204 | Frame_Shift_Del | NA | G2425Vfs*15 | 0.33 | |
| COAD | chr11 | 108365360 | Missense_Mutation | rs587781894 | R3008H | 0.41 | |
| DLBC | chr11 | 108331991 | Missense_Mutation | novel | S2581T | 0.26 | |
| ESCA | chr11 | 108332854 | Silent | novel | Y2627Y | 0.29 | |
| ESCA | chr11 | 108279550 | Missense_Mutation | novel | L1115P | 0.29 | |
| ESCA | chr11 | 108315862 | Missense_Mutation | novel | D2016H | 0.31 | |
| ESCA | chr11 | 108293374 | Missense_Mutation | rs587781712 | T1558M | 0.2 | |
| ESCA | chr11 | 108284472 | Missense_Mutation | novel | Q1331R | 0.1 | |
| ESCA | chr11 | 108272801 | Missense_Mutation | novel | L1078R | 0.15 | |
| ESCA | chr11 | 108343255 | Missense_Mutation | novel | E2768Q | 0.1 | |
| GBM | chr11 | 108330381 | Missense_Mutation | rs56399857 | L2492R | 0.28 | |
| GBM | chr11 | 108279585 | Missense_Mutation | novel | A1127T | 0.21 | |
| GBM | chr11 | 108301728 | Missense_Mutation | rs777481236 | Y1753C | 0.51 | |
| GBM | chr11 | 108250940 | Missense_Mutation | novel | F492C | 0.39 | |
| GBM | chr11 | 108268521 | Missense_Mutation | novel | S917F | 0.46 | |
| GBM | chr11 | 108289015 | Missense_Mutation | rs141087784 | S1383L | 0.38 | |
| GBM | chr11 | 108292782 | Missense_Mutation | novel | V1534I | 0.2 | |
| GBM | chr11 | 108329155 | Frame_Shift_Del | novel | E2409Nfs*9 | 0.19 | |
| HNSC | chr11 | 108353791 | Missense_Mutation | novel | I2899M | 0.42 | |
| HNSC | chr11 | 108365193 | Missense_Mutation | novel | D2988N | 0.08 | |
| HNSC | chr11 | 108335953 | Missense_Mutation | rs587781414 | T2754A | 0.23 | |
| HNSC | chr11 | 108327667 | Missense_Mutation | rs150503164 | T2333I | 0.34 | |
| HNSC | chr11 | 108354818 | Missense_Mutation | novel | E2932K | 0.29 | |
| HNSC | chr11 | 108235710 | Silent | novel | I124I | 0.26 | |
| HNSC | chr11 | 108289679 | Silent | novel | I1438I | 0.09 | |
| HNSC | chr11 | 108247071 | Missense_Mutation | rs138398778 | R337C | 0.79 | |
| HNSC | chr11 | 108272725 | Missense_Mutation | novel | D1053N | 0.23 | |
| HNSC | chr11 | 108244837 | Missense_Mutation | rs754275014 | I238V | 0.31 | |
| HNSC | chr11 | 108272557 | Missense_Mutation | novel | I1035V | 0.3 | |
| HNSC | chr11 | 108302995 | Nonsense_Mutation | novel | C1821* | 0.1 | |
| HNSC | chr11 | 108365326 | Missense_Mutation | novel | D2997N | 0.41 | |
| HNSC | chr11 | 108325449 | Missense_Mutation | novel | E2238Q | 0.11 | |
| HNSC | chr11 | 108335940 | Missense_Mutation | novel | K2749N | 0.54 | |
| HNSC | chr11 | 108301645 | Splice_Region | novel | 0.2 | ||
| HNSC | chr11 | 108292698 | Missense_Mutation | novel | V1506M | 0.11 | |
| HNSC | chr11 | 108343257 | Silent | rs756686570 | E2768E | 0.75 | |
| HNSC | chr11 | 108250701 | Missense_Mutation | novel | W412C | 0.14 | |
| KICH | chr11 | 108256261 | Missense_Mutation | novel | G724V | 0.31 | |
| KICH | chr11 | 108330287 | Missense_Mutation | rs201314561 | R2461C | 0.58 | |
| KIRC | chr11 | 108256336 | Frame_Shift_Del | novel | K750Sfs*3 | 0.31 | |
| KIRC | chr11 | 108271147 | Splice_Site | rs587781558 | X974_splice | 0.08 | |
| KIRC | chr11 | 108316109 | Frame_Shift_Del | novel | Q2066Rfs*16 | 0.31 | |
| KIRC | chr11 | 108365347 | Missense_Mutation | NA | K3004E | 0.13 | |
| KIRC | chr11 | 108268425 | Frame_Shift_Del | novel | A886Kfs*12 | 0.14 | |
| KIRC | chr11 | 108279573 | Missense_Mutation | novel | A1123T | 0.13 | |
| KIRC | chr11 | 108299741 | Missense_Mutation | NA | V1678G | 0.25 | |
| KIRC | chr11 | 108271089 | Missense_Mutation | NA | P955L | 0.05 | |
| KIRC | chr11 | 108330386 | Missense_Mutation | NA | N2494Y | 0.32 | |
| KIRC | chr11 | 108332890 | Frame_Shift_Del | NA | T2640Lfs*6 | 0.34 | |
| KIRC | chr11 | 108288972 | Splice_Site | novel | X1370_splice | 0.23 | |
| KIRC | chr11 | 108250952 | Frame_Shift_Del | novel | S496Ifs*16 | 0.17 | |
| KIRC | chr11 | 108331987 | Nonsense_Mutation | NA | R2580* | 0.21 | |
| KIRC | chr11 | 108335845 | Missense_Mutation | NA | G2718R | 0.5 | |
| KIRC | chr11 | 108325528 | Missense_Mutation | NA | T2264I | 0.21 | |
| KIRC | chr11 | 108244873 | Nonsense_Mutation | rs772821016 | R250* | 0.3 | |
| KIRC | chr11 | 108256335 | Missense_Mutation | NA | A749T | 0.33 | |
| KIRC | chr11 | 108268497 | Missense_Mutation | novel | T909I | 0.22 | |
| KIRC | chr11 | 108329186 | Nonsense_Mutation | NA | R2419* | 0.28 | |
| KIRP | chr11 | 108365352 | Silent | novel | V3005V | 0.73 | |
| KIRP | chr11 | 108343246 | Missense_Mutation | rs748634900 | G2765S | 0.05 | |
| KIRP | chr11 | 108335882 | Missense_Mutation | NA | Q2730P | 0.34 | |
| KIRP | chr11 | 108272609 | Splice_Site | NA | X1051_splice | 0.1 | |
| KIRP | chr11 | 108284475 | Splice_Site | NA | X1331_splice | 0.35 | |
| LAML | chr11 | 108267268 | Missense_Mutation | novel | M855K | 0.18 | |
| LAML | chr11 | 108327698 | Missense_Mutation | novel | N2343K | 0.2 | |
| LAML | chr11 | 108345837 | Missense_Mutation | novel | K2838I | 0.07 | |
| LGG | chr11 | 108254032 | Nonsense_Mutation | novel | S706* | 0.39 | |
| LGG | chr11 | 108250763 | Missense_Mutation | novel | S433Y | 0.13 | |
| LGG | chr11 | 108251848 | Missense_Mutation | NA | C540Y | 0.44 | |
| LGG | chr11 | 108282862 | Silent | novel | N1243N | 0.09 | |
| LGG | chr11 | 108295003 | Missense_Mutation | rs765759912 | R1618Q | 0.44 | |
| LGG | chr11 | 108287653 | In_Frame_Del | novel | T1350del | 0.94 | |
| LIHC | chr11 | 108297284 | Splice_Region | novel | 0.38 | ||
| LIHC | chr11 | 108247071 | Missense_Mutation | rs138398778 | R337C | 0.32 | |
| LIHC | chr11 | 108256305 | Nonsense_Mutation | NA | E739* | 0.38 | |
| LIHC | chr11 | 108304719 | Silent | NA | H1847H | 0.43 | |
| LIHC | chr11 | 108267304 | Missense_Mutation | NA | S867T | 0.47 | |
| LIHC | chr11 | 108335880 | Missense_Mutation | rs587781946 | Q2729H | 0.56 | |
| LIHC | chr11 | 108329214 | Missense_Mutation | novel | R2428T | 0.1 | |
| LIHC | chr11 | 108334967 | Splice_Site | novel | X2671_splice | 0.56 | |
| LIHC | chr11 | 108301772 | Missense_Mutation | NA | R1768G | 0.13 | |
| LIHC | chr11 | 108244111 | Missense_Mutation | novel | C219S | 0.36 | |
| LIHC | chr11 | 108347348 | Missense_Mutation | NA | L2885H | 0.49 | |
| LIHC | chr11 | 108243977 | Missense_Mutation | NA | L174R | 0.23 | |
| LIHC | chr11 | 108253957 | Missense_Mutation | novel | S681C | 0.39 | |
| LUAD | chr11 | 108287598 | Splice_Site | novel | X1332_splice | 0.22 | |
| LUAD | chr11 | 108289685 | Missense_Mutation | novel | K1440N | 0.28 | |
| LUAD | chr11 | 108312427 | Nonsense_Mutation | NA | E1979* | 0.19 | |
| LUAD | chr11 | 108335041 | Missense_Mutation | NA | G2695S | 0.43 | |
| LUAD | chr11 | 108345818 | Missense_Mutation | rs587779872 | R2832C | 0.24 | |
| LUAD | chr11 | 108252896 | Nonsense_Mutation | NA | Q628* | 0.1 | |
| LUAD | chr11 | 108335041 | Missense_Mutation | NA | G2695C | 0.33 | |
| LUAD | chr11 | 108247128 | Splice_Site | NA | X355_splice | 0.17 | |
| LUAD | chr11 | 108282806 | Nonsense_Mutation | novel | Q1225* | 0.12 | |
| LUAD | chr11 | 108244081 | Frame_Shift_Del | novel | L210Wfs*20 | 0.12 | |
| LUAD | chr11 | 108365380 | Nonsense_Mutation | NA | E3015* | 0.59 | |
| LUAD | chr11 | 108272538 | Frame_Shift_Del | novel | T1029Qfs*10 | 0.67 | |
| LUAD | chr11 | 108267225 | Missense_Mutation | NA | D841Y | 0.54 | |
| LUAD | chr11 | 108244873 | Frame_Shift_Del | novel | R250Sfs*3 | 0.24 | |
| LUAD | chr11 | 108315832 | Frame_Shift_Del | novel | L2006* | 0.3 | |
| LUAD | chr11 | 108244867 | Nonsense_Mutation | rs730881336 | R248* | 0.07 | |
| LUAD | chr11 | 108365106 | Missense_Mutation | NA | D2959H | 0.2 | |
| LUAD | chr11 | 108335851 | Missense_Mutation | NA | D2720H | 0.13 | |
| LUAD | chr11 | 108332853 | Missense_Mutation | rs767670019 | Y2627C | 0.54 | |
| LUAD | chr11 | 108259065 | Frame_Shift_Del | novel | C819Lfs*4 | 0.31 | |
| LUAD | chr11 | 108284453 | Missense_Mutation | novel | E1325Q | 0.13 | |
| LUAD | chr11 | 108299759 | Missense_Mutation | novel | S1684C | 0.44 | |
| LUAD | chr11 | 108253862 | Missense_Mutation | novel | E649D | 0.39 | |
| LUAD | chr11 | 108271092 | Missense_Mutation | rs752099312 | G956E | 0.09 | |
| LUAD | chr11 | 108304689 | Missense_Mutation | novel | F1837L | 0.19 | |
| LUAD | chr11 | 108247071 | Missense_Mutation | rs138398778 | R337C | 0.63 | |
| LUAD | chr11 | 108310314 | Missense_Mutation | rs786202089 | R1973G | 0.07 | |
| LUAD | chr11 | 108347363 | Missense_Mutation | NA | L2890R | 0.43 | |
| LUAD | chr11 | 108289674 | Nonsense_Mutation | NA | R1437* | 0.14 | |
| LUAD | chr11 | 108251917 | Missense_Mutation | NA | M563T | 0.38 | |
| LUAD | chr11 | 108257538 | Nonsense_Mutation | NA | E770* | 0.31 | |
| LUAD | chr11 | 108333962 | Splice_Site | novel | X2669_splice | 0.19 | |
| LUAD | chr11 | 108268523 | Frame_Shift_Ins | novel | I923* | 0.38 | |
| LUAD | chr11 | 108245008 | Missense_Mutation | NA | A295P | 0.51 | |
| LUAD | chr11 | 108316043 | Missense_Mutation | rs753384717 | G2043V | 0.42 | |
| LUAD | chr11 | 108289009 | Missense_Mutation | NA | F1381C | 0.05 | |
| LUAD | chr11 | 108329168 | Missense_Mutation | NA | K2413Q | 0.1 | |
| LUAD | chr11 | 108272721 | Splice_Site | NA | X1052_splice | 0.26 | |
| LUAD | chr11 | 108365106 | Missense_Mutation | novel | D2959N | 0.24 | |
| LUAD | chr11 | 108365360 | Missense_Mutation | rs587781894 | R3008H | 0.23 | |
| LUAD | chr11 | 108343268 | Missense_Mutation | rs775293524 | G2772E | 0.1 | |
| LUAD | chr11 | 108257480 | Frame_Shift_Ins | novel | S751Ffs*14 | 0.15 | |
| LUAD | chr11 | 108292642 | Nonsense_Mutation | NA | S1487* | 0.3 | |
| LUAD | chr11 | 108272825 | Missense_Mutation | rs769857066 | R1086L | 0.68 | |
| LUAD | chr11 | 108312489 | Frame_Shift_Ins | novel | S2000Nfs*4 | 0.1 | |
| LUAD | chr11 | 108312417 | Silent | NA | L1975L | 0.1 | |
| LUAD | chr11 | 108335080 | Missense_Mutation | rs587782719 | D2708N | 0.53 | |
| LUAD | chr11 | 108325452 | Missense_Mutation | novel | M2239V | 0.04 | |
| LUAD | chr11 | 108253892 | Missense_Mutation | novel | K659N | 0.16 | |
| LUAD | chr11 | 108282719 | Nonsense_Mutation | NA | K1196* | 0.73 | |
| LUAD | chr11 | 108268463 | Missense_Mutation | NA | L898V | 0.13 | |
| LUAD | chr11 | 108347325 | Silent | NA | L2877L | 0.06 | |
| LUAD | chr11 | 108329194 | Missense_Mutation | novel | K2421N | 0.24 | |
| LUAD | chr11 | 108250745 | Nonsense_Mutation | NA | L427* | 0.24 | |
| LUAD | chr11 | 108335102 | Missense_Mutation | NA | L2715R | 0.48 | |
| LUAD | chr11 | 108365493 | Missense_Mutation | NA | W3052C | 0.39 | |
| LUAD | chr11 | 108331565 | Splice_Region | novel | 0.27 | ||
| LUSC | chr11 | 108244814 | Missense_Mutation | novel | N230I | 0.33 | |
| LUSC | chr11 | 108227808 | Silent | NA | R35R | 0.27 | |
| LUSC | chr11 | 108229330 | Splice_Region | novel | 0.53 | ||
| LUSC | chr11 | 108297364 | Missense_Mutation | NA | G1663C | 0.23 | |
| LUSC | chr11 | 108249083 | Missense_Mutation | NA | D406N | 0.16 | |
| LUSC | chr11 | 108229185 | Nonsense_Mutation | novel | Q65* | 0.5 | |
| LUSC | chr11 | 108284434 | Silent | novel | V1318V | 0.14 | |
| LUSC | chr11 | 108333908 | Missense_Mutation | novel | D2650E | 0.04 | |
| LUSC | chr11 | 108288984 | Missense_Mutation | novel | D1373N | 0.2 | |
| LUSC | chr11 | 108293343 | Missense_Mutation | novel | D1548H | 0.42 | |
| LUSC | chr11 | 108294992 | Silent | novel | L1614L | 0.44 | |
| LUSC | chr11 | 108329112 | Missense_Mutation | rs587779861 | S2394L | 0.45 | |
| LUSC | chr11 | 108299827 | Missense_Mutation | novel | E1707K | 0.13 | |
| LUSC | chr11 | 108289657 | Missense_Mutation | rs201356803 | N1431S | 0.3 | |
| LUSC | chr11 | 108284447 | Missense_Mutation | NA | K1323E | 0.13 | |
| LUSC | chr11 | 108329182 | Silent | novel | L2417L | 0.42 | |
| LUSC | chr11 | 108302987 | Silent | novel | G1818G | 0.36 | |
| LUSC | chr11 | 108252004 | Missense_Mutation | rs776911505 | S592N | 0.15 | |
| LUSC | chr11 | 108353831 | Missense_Mutation | rs756899044 | D2913H | 0.3 | |
| LUSC | chr11 | 108331876 | Splice_Region | novel | 0.2 | ||
| LUSC | chr11 | 108292754 | Frame_Shift_Ins | novel | I1525Nfs*6 | 0.21 | |
| LUSC | chr11 | 108353783 | Missense_Mutation | NA | G2897S | 0.33 | |
| LUSC | chr11 | 108304790 | Missense_Mutation | rs538452060 | T1871I | 0.42 | |
| LUSC | chr11 | 108365190 | Missense_Mutation | NA | D2987Y | 0.09 | |
| LUSC | chr11 | 108347339 | Nonsense_Mutation | novel | S2882* | 0.22 | |
| LUSC | chr11 | 108326079 | Nonsense_Mutation | novel | Q2277* | 0.46 | |
| LUSC | chr11 | 108299733 | Missense_Mutation | NA | L1675F | 0.12 | |
| LUSC | chr11 | 108252008 | Silent | novel | T593T | 0.26 | |
| LUSC | chr11 | 108295073 | Intron | novel | 0.31 | ||
| LUSC | chr11 | 108271394 | Missense_Mutation | novel | I1022T | 0.26 | |
| LUSC | chr11 | 108354817 | Missense_Mutation | novel | C2931W | 0.25 | |
| LUSC | chr11 | 108320030 | Missense_Mutation | novel | T2142A | 0.29 | |
| LUSC | chr11 | 108227775 | Splice_Site | NA | X25_splice | 0.17 | |
| LUSC | chr11 | 108279550 | Frame_Shift_Del | novel | Q1116Sfs*10 | 0.49 | |
| LUSC | chr11 | 108343225 | Missense_Mutation | novel | V2758L | 0.23 | |
| LUSC | chr11 | 108320019 | Missense_Mutation | novel | R2138T | 0.11 | |
| OV | chr11 | 108295313 | Intron | novel | 0.19 | ||
| OV | chr11 | 108284412 | Missense_Mutation | novel | Q1311L | 0.05 | |
| OV | chr11 | 108244042 | Missense_Mutation | novel | K196E | 0.17 | |
| OV | chr11 | 108310180 | Missense_Mutation | NA | F1928C | 0.25 | |
| OV | chr11 | 108282755 | Missense_Mutation | NA | D1208H | 0.18 | |
| OV | chr11 | 108244853 | Missense_Mutation | rs786202096 | L243S | 0.46 | |
| OV | chr11 | 108329171 | Nonsense_Mutation | NA | Q2414* | 0.43 | |
| OV | chr11 | 108307971 | Splice_Site | NA | X1917_splice | 0.25 | |
| OV | chr11 | 108257568 | Missense_Mutation | novel | M780V | 0.07 | |
| OV | chr11 | 108250816 | Missense_Mutation | rs201719927 | R451C | 0.56 | |
| OV | chr11 | 108331447 | Missense_Mutation | NA | D2507N | 0.32 | |
| OV | chr11 | 108326113 | Missense_Mutation | novel | V2288A | 0.12 | |
| OV | chr11 | 108227692 | Missense_Mutation | rs587779858 | R23Q | 0.48 | |
| OV | chr11 | 108365092 | Missense_Mutation | rs767507047 | Y2954C | 0.38 | |
| OV | chr11 | 108271340 | Missense_Mutation | novel | S1004I | 0.16 | |
| PAAD | chr11 | 108365426 | Missense_Mutation | NA | G3030V | 0.41 | |
| PAAD | chr11 | 108287646 | Nonsense_Mutation | NA | L1347* | 0.88 | |
| PAAD | chr11 | 108329199 | Missense_Mutation | rs121434221 | E2423G | 0.49 | |
| PAAD | chr11 | 108253812 | Splice_Site | novel | X633_splice | 0.6 | |
| PAAD | chr11 | 108327727 | Missense_Mutation | novel | P2353H | 0.17 | |
| PAAD | chr11 | 108330281 | Missense_Mutation | rs730881383 | R2459C | 0.2 | |
| PAAD | chr11 | 108343292 | Missense_Mutation | NA | L2780R | 0.18 | |
| PAAD | chr11 | 108354825 | Missense_Mutation | novel | T2934I | 0.15 | |
| PAAD | chr11 | 108271057 | Splice_Site | novel | X947_splice | 0.13 | |
| PAAD | chr11 | 108307915 | Missense_Mutation | rs370680798 | R1898Q | 0.04 | |
| PAAD | chr11 | 108247071 | Missense_Mutation | rs138398778 | R337C | 0.17 | |
| PCPG | chr11 | 108303008 | Silent | novel | Q1825Q | 0.09 | |
| PRAD | chr11 | 108347318 | Missense_Mutation | rs587782451 | N2875S | 0.91 | |
| PRAD | chr11 | 108247071 | Missense_Mutation | rs138398778 | R337C | 0.61 | |
| PRAD | chr11 | 108335041 | Missense_Mutation | NA | G2695S | 0.13 | |
| PRAD | chr11 | 108343309 | Missense_Mutation | NA | G2786S | 0.25 | |
| PRAD | chr11 | 108353851 | Silent | novel | G2919G | 0.23 | |
| PRAD | chr11 | 108272558 | In_Frame_Del | novel | F1036_V1038del | 0.47 | |
| PRAD | chr11 | 108330264 | Missense_Mutation | NA | R2453P | 0.77 | |
| PRAD | chr11 | 108310204 | Missense_Mutation | NA | L1936S | 0.27 | |
| PRAD | chr11 | 108289053 | Frame_Shift_Del | novel | C1396* | 0.19 | |
| PRAD | chr11 | 108293404 | Missense_Mutation | NA | H1568L | 0.07 | |
| PRAD | chr11 | 108321338 | Missense_Mutation | NA | E2164K | 0.34 | |
| PRAD | chr11 | 108310208 | Frame_Shift_Del | novel | Y1938Ifs*2 | 0.26 | |
| PRAD | chr11 | 108304715 | Missense_Mutation | novel | I1846N | 0.42 | |
| PRAD | chr11 | 108272800 | Missense_Mutation | NA | L1078V | 0.09 | |
| PRAD | chr11 | 108299723 | Missense_Mutation | NA | G1672A | 0.11 | |
| PRAD | chr11 | 108250916 | Frame_Shift_Del | novel | W484* | 0.22 | |
| PRAD | chr11 | 108354834 | Missense_Mutation | NA | V2937G | 0.15 | |
| PRAD | chr11 | 108329056 | Silent | novel | S2375S | 0.39 | |
| PRAD | chr11 | 108347319 | Missense_Mutation | NA | N2875K | 0.22 | |
| PRAD | chr11 | 108254008 | Frame_Shift_Del | novel | S698* | 0.17 | |
| PRAD | chr11 | 108335038 | Missense_Mutation | NA | G2694R | 0.22 | |
| READ | chr11 | 108247071 | Missense_Mutation | rs138398778 | R337C | 0.53 | |
| READ | chr11 | 108259012 | Silent | novel | G801G | 0.25 | |
| READ | chr11 | 108301658 | Nonsense_Mutation | rs764389018 | R1730* | 0.29 | |
| READ | chr11 | 108244797 | Missense_Mutation | rs769731317 | K224N | 0.32 | |
| READ | chr11 | 108345759 | Missense_Mutation | NA | S2812Y | 0.46 | |
| READ | chr11 | 108247071 | Missense_Mutation | rs138398778 | R337C | 0.28 | |
| READ | chr11 | 108365345 | Missense_Mutation | rs144636562 | N3003S | 0.35 | |
| READ | chr11 | 108347318 | Missense_Mutation | rs587782451 | N2875S | 0.26 | |
| READ | chr11 | 108247072 | Missense_Mutation | rs202160435 | R337H | 0.48 | |
| READ | chr11 | 108345869 | Nonsense_Mutation | rs587778080 | R2849* | 0.24 | |
| READ | chr11 | 108271262 | Missense_Mutation | novel | S978Y | 0.19 | |
| READ | chr11 | 108331918 | Missense_Mutation | NA | L2557V | 0.21 | |
| READ | chr11 | 108268595 | Missense_Mutation | novel | L942I | 0.39 | |
| READ | chr11 | 108281041 | Missense_Mutation | novel | R1150I | 0.38 | |
| READ | chr11 | 108282782 | Missense_Mutation | novel | L1217M | 0.38 | |
| READ | chr11 | 108287545 | Intron | novel | 0.3 | ||
| READ | chr11 | 108289089 | Missense_Mutation | NA | L1408I | 0.31 | |
| READ | chr11 | 108289761 | Nonsense_Mutation | rs730881369 | R1466* | 0.46 | |
| READ | chr11 | 108292646 | Silent | novel | L1488L | 0.38 | |
| READ | chr11 | 108295343 | Intron | novel | 0.6 | ||
| READ | chr11 | 108301658 | Nonsense_Mutation | rs764389018 | R1730* | 0.39 | |
| READ | chr11 | 108320045 | Missense_Mutation | novel | L2147I | 0.3 | |
| READ | chr11 | 108325488 | Missense_Mutation | novel | L2251I | 0.4 | |
| READ | chr11 | 108244873 | Nonsense_Mutation | rs772821016 | R250* | 0.17 | |
| READ | chr11 | 108289089 | Missense_Mutation | NA | L1408I | 0.21 | |
| READ | chr11 | 108299752 | Missense_Mutation | NA | D1682Y | 0.3 | |
| READ | chr11 | 108316030 | Missense_Mutation | NA | E2039K | 0.45 | |
| READ | chr11 | 108307985 | Splice_Site | novel | X1921_splice | 0.35 | |
| READ | chr11 | 108326152 | Frame_Shift_Ins | rs773570504 | E2304Gfs*69 | 0.43 | |
| SARC | chr11 | 108249053 | Missense_Mutation | novel | I396L | 0.12 | |
| SARC | chr11 | 108289040 | Silent | novel | A1391A | 0.22 | |
| SARC | chr11 | 108282718 | Silent | novel | E1195E | 0.4 | |
| SARC | chr11 | 108247071 | Missense_Mutation | rs138398778 | R337C | 0.8 | |
| SARC | chr11 | 108287482 | Intron | novel | 0.39 | ||
| SARC | chr11 | 108287545 | Intron | novel | 0.37 | ||
| SARC | chr11 | 108293467 | Missense_Mutation | novel | S1589L | 0.79 | |
| SARC | chr11 | 108329178 | Missense_Mutation | NA | L2416P | 0.58 | |
| SARC | chr11 | 108249065 | Missense_Mutation | novel | L400I | 0.29 | |
| SARC | chr11 | 108289070 | Frame_Shift_Del | novel | S1403Afs*3 | 0.2 | |
| SARC | chr11 | 108289075 | Missense_Mutation | novel | S1403I | 0.19 | |
| SKCM | chr11 | 108316081 | Missense_Mutation | NA | P2056S | 0.29 | |
| SKCM | chr11 | 108253907 | Silent | NA | T664T | 0.27 | |
| SKCM | chr11 | 108343347 | Silent | novel | A2798A | 0.44 | |
| SKCM | chr11 | 108316107 | Silent | novel | I2064I | 0.21 | |
| SKCM | chr11 | 108247071 | Missense_Mutation | rs138398778 | R337C | 0.54 | |
| SKCM | chr11 | 108247071 | Missense_Mutation | rs138398778 | R337C | 0.23 | |
| SKCM | chr11 | 108267287 | Silent | NA | Y861Y | 0.24 | |
| SKCM | chr11 | 108287592 | Splice_Region | novel | 0.1 | ||
| SKCM | chr11 | 108331548 | Silent | NA | V2540V | 0.23 | |
| SKCM | chr11 | 108331903 | Missense_Mutation | novel | H2552Y | 0.06 | |
| SKCM | chr11 | 108272773 | Missense_Mutation | rs751714261 | P1069S | 0.61 | |
| SKCM | chr11 | 108235828 | Frame_Shift_Ins | novel | 0.45 | ||
| SKCM | chr11 | 108289010 | Silent | NA | F1381F | 0.28 | |
| SKCM | chr11 | 108292658 | Silent | rs780236656 | S1492S | 0.19 | |
| SKCM | chr11 | 108250753 | Missense_Mutation | NA | C430S | 0.43 | |
| SKCM | chr11 | 108250835 | Missense_Mutation | rs780097986 | R457Q | 0.39 | |
| SKCM | chr11 | 108331505 | Missense_Mutation | NA | R2526K | 0.29 | |
| SKCM | chr11 | 108268522 | Silent | NA | S917S | 0.69 | |
| SKCM | chr11 | 108321351 | Missense_Mutation | rs200431631 | S2168L | 0.43 | |
| SKCM | chr11 | 108289692 | Missense_Mutation | novel | H1443Y | 0.14 | |
| SKCM | chr11 | 108343228 | Missense_Mutation | rs764906663 | P2759S | 0.37 | |
| SKCM | chr11 | 108293366 | Silent | rs374431061 | L1555L | 0.42 | |
| SKCM | chr11 | 108259019 | Silent | novel | L804L | 0.22 | |
| SKCM | chr11 | 108304821 | Silent | NA | S1881S | 0.33 | |
| SKCM | chr11 | 108365484 | Silent | NA | F3049F | 0.39 | |
| SKCM | chr11 | 108251034 | Silent | NA | F523F | 0.36 | |
| SKCM | chr11 | 108310237 | Missense_Mutation | novel | S1947Y | 0.82 | |
| SKCM | chr11 | 108295005 | Silent | novel | R1619R | 0.2 | |
| SKCM | chr11 | 108326226 | Splice_Site | NA | X2325_splice | 0.53 | |
| SKCM | chr11 | 108317469 | Missense_Mutation | novel | H2099Y | 0.57 | |
| SKCM | chr11 | 108294935 | Silent | novel | N1595N | 0.3 | |
| SKCM | chr11 | 108284415 | Missense_Mutation | NA | R1312K | 0.56 | |
| SKCM | chr11 | 108353791 | Silent | NA | I2899I | 0.32 | |
| SKCM | chr11 | 108354834 | Missense_Mutation | NA | V2937G | 0.33 | |
| SKCM | chr11 | 108327758 | Missense_Mutation | NA | K2363N | 0.77 | |
| SKCM | chr11 | 108268594 | Silent | NA | S941S | 0.56 | |
| SKCM | chr11 | 108244993 | Missense_Mutation | NA | H290Y | 0.23 | |
| SKCM | chr11 | 108250850 | Missense_Mutation | NA | V462A | 0.31 | |
| SKCM | chr11 | 108365179 | Missense_Mutation | NA | T2983S | 0.06 | |
| SKCM | chr11 | 108335029 | Missense_Mutation | rs531980488 | R2691C | 0.25 | |
| SKCM | chr11 | 108227806 | Nonsense_Mutation | rs55861249 | R35* | 0.67 | |
| SKCM | chr11 | 108332840 | Missense_Mutation | NA | L2623F | 0.97 | |
| SKCM | chr11 | 108284284 | Silent | NA | V1268V | 0.19 | |
| STAD | chr11 | 108331930 | Missense_Mutation | NA | L2561M | 0.1 | |
| STAD | chr11 | 108244096 | Missense_Mutation | rs747053710 | S214P | 0.25 | |
| STAD | chr11 | 108292680 | Nonsense_Mutation | NA | Q1500* | 0.39 | |
| STAD | chr11 | 108330378 | Missense_Mutation | NA | W2491L | 0.26 | |
| STAD | chr11 | 108259057 | Silent | NA | A816A | 0.16 | |
| STAD | chr11 | 108247085 | Frame_Shift_Ins | novel | E343Rfs*5 | 0.29 | |
| STAD | chr11 | 108289748 | Missense_Mutation | NA | W1461C | 0.19 | |
| STAD | chr11 | 108301698 | Frame_Shift_Ins | novel | T1745Dfs*4 | 0.48 | |
| STAD | chr11 | 108272851 | Missense_Mutation | NA | R1095G | 0.23 | |
| STAD | chr11 | 108330350 | Missense_Mutation | novel | M2482V | 0.24 | |
| STAD | chr11 | 108289762 | Missense_Mutation | rs749770110 | R1466Q | 0.23 | |
| STAD | chr11 | 108247047 | Frame_Shift_Del | novel | R329Kfs*8 | 0.12 | |
| STAD | chr11 | 108299727 | Silent | NA | S1673S | 0.24 | |
| STAD | chr11 | 108227692 | Missense_Mutation | rs587779858 | R23Q | 0.37 | |
| STAD | chr11 | 108267315 | Missense_Mutation | NA | E871K | 0.39 | |
| STAD | chr11 | 108332765 | Nonsense_Mutation | rs138941496 | R2598* | 0.23 | |
| STAD | chr11 | 108343240 | Nonsense_Mutation | NA | R2763* | 0.23 | |
| STAD | chr11 | 108281160 | Missense_Mutation | novel | V1190L | 0.35 | |
| STAD | chr11 | 108317444 | Missense_Mutation | novel | D2090E | 0.16 | |
| STAD | chr11 | 108284434 | Silent | NA | V1318V | 0.29 | |
| STAD | chr11 | 108289070 | Frame_Shift_Del | novel | S1403Afs*3 | 0.27 | |
| STAD | chr11 | 108293436 | Frame_Shift_Ins | NA | I1581Nfs*5 | 0.12 | |
| STAD | chr11 | 108329124 | Missense_Mutation | NA | Y2398C | 0.12 | |
| STAD | chr11 | 108325469 | Silent | novel | R2244R | 0.07 | |
| STAD | chr11 | 108307929 | Frame_Shift_Del | novel | K1904Nfs*13 | 0.38 | |
| STAD | chr11 | 108284386 | Silent | NA | G1302G | 0.1 | |
| STAD | chr11 | 108329159 | Missense_Mutation | rs193302874 | F2410L | 0.64 | |
| STAD | chr11 | 108247071 | Missense_Mutation | rs138398778 | R337C | 0.18 | |
| STAD | chr11 | 108347362 | Missense_Mutation | rs587779874 | L2890V | 0.24 | |
| STAD | chr11 | 108272574 | Missense_Mutation | novel | M1040I | 0.33 | |
| STAD | chr11 | 108335080 | Missense_Mutation | rs587782719 | D2708N | 0.31 | |
| STAD | chr11 | 108250979 | Missense_Mutation | novel | F505C | 0.15 | |
| STAD | chr11 | 108345750 | Frame_Shift_Del | rs759472682 | K2811Sfs*46 | 0.14 | |
| STAD | chr11 | 108345818 | Missense_Mutation | rs587779872 | R2832C | 0.21 | |
| STAD | chr11 | 108244090 | Frame_Shift_Del | NA | S214Pfs*16 | 0.22 | |
| STAD | chr11 | 108244856 | Missense_Mutation | NA | A244V | 0.16 | |
| STAD | chr11 | 108345750 | Frame_Shift_Del | novel | K2811Vfs*3 | 0.76 | |
| STAD | chr11 | 108289059 | Frame_Shift_Del | novel | T1399Pfs*3 | 0.27 | |
| STAD | chr11 | 108247071 | Missense_Mutation | rs138398778 | R337C | 0.2 | |
| STAD | chr11 | 108345750 | Frame_Shift_Del | rs759472682 | K2811Sfs*46 | 0.2 | |
| STAD | chr11 | 108227689 | Missense_Mutation | novel | E22G | 0.1 | |
| STAD | chr11 | 108304823 | Missense_Mutation | rs587782236 | R1882Q | 0.34 | |
| STAD | chr11 | 108321300 | Splice_Site | NA | X2151_splice | 0.11 | |
| STAD | chr11 | 108345750 | Frame_Shift_Del | rs759472682 | K2811Sfs*46 | 0.4 | |
| STAD | chr11 | 108365142 | Nonsense_Mutation | NA | Q2971* | 0.16 | |
| STAD | chr11 | 108227636 | Silent | rs786201365 | V4V | 0.3 | |
| STAD | chr11 | 108297354 | Missense_Mutation | NA | I1659M | 0.16 | |
| STAD | chr11 | 108335015 | Missense_Mutation | NA | F2686C | 0.6 | |
| STAD | chr11 | 108257498 | Silent | NA | A756A | 0.08 | |
| STAD | chr11 | 108289089 | Missense_Mutation | NA | L1408F | 0.14 | |
| STAD | chr11 | 108331949 | Missense_Mutation | NA | N2567S | 0.16 | |
| STAD | chr11 | 108365359 | Missense_Mutation | rs587782292 | R3008C | 0.17 | |
| STAD | chr11 | 108343322 | Missense_Mutation | NA | R2790K | 0.22 | |
| STAD | chr11 | 108304812 | Silent | rs767070325 | S1878S | 0.12 | |
| STAD | chr11 | 108289724 | Frame_Shift_Del | novel | S1455Vfs*3 | 0.43 | |
| STAD | chr11 | 108247066 | Missense_Mutation | NA | G335E | 0.09 | |
| STAD | chr11 | 108250960 | Nonsense_Mutation | novel | Q499* |
