EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
17974966	BAG3 regulates motility and adhesion of epithelial cancer cells.	Cancer Res	2007 Nov 1	Iwasaki M	-
30081850	Bcl-2-associated athanogene 3(BAG3) is associated with tumor cell proliferation, migration, invasion and chemoresistance in colorectal cancer.	BMC Cancer	2018 Aug 6	Li N	doi: 10.1186/s12885-018-4657-2.
22072743	BAG3 down-modulation reduces anaplastic thyroid tumor growth by enhancing proteasome-mediated degradation of BRAF protein.	J Clin Endocrinol Metab	2012 Jan	Chiappetta G	doi: 10.1210/jc.2011-0484
21850027	Expression of the anti-apoptotic protein BAG3 in human melanomas.	J Invest Dermatol	2012 Jan	Franco R	doi: 10.1038/jid.2011.257
26621836	BAG3 elevation inhibits cell proliferation via direct interaction with G6PD in hepatocellular carcinomas.	Oncotarget	2016 Jan 5	Kong DH	doi: 10.18632/oncotarget.6396.
26541455	MiR-143 enhances the antitumor activity of shikonin by targeting BAG3 expression in human glioblastoma stem cells.	Biochem Biophys Res Commun	2015 Dec 4-11	Liu J	doi: 10.1016/j.bbrc.2015.10.153
26577854	BAG3 regulates cell proliferation, migration, and invasion in human colorectal cancer.	Tumour Biol	2016 Apr	Shi H	doi: 10.1007/s13277-015-4403-1
20535599	BAG3 protein delocalisation in prostate carcinoma.	Tumour Biol	2010 Oct	Staibano S	doi: 10.1007/s13277-010-0055-3
24577090	Knockdown of BAG3 induces epithelial-mesenchymal transition in thyroid cancer cells through ZEB1 activation.	Cell Death Dis	2014 Feb 27	Meng X	doi: 10.1038/cddis.2014.32.
21316839	BAG3 (BCL2-associated athanogene 3) interacts with MMP-2 to positively regulate invasion by ovarian carcinoma cells.	Cancer Lett	2011 Apr 1	Suzuki M	doi: 10.1016/j.canlet.2011.01.019
25347739	Hsp70 in cancer: back to the future.	Oncogene	2015 Aug 6	Sherman MY	doi: 10.1038/onc.2014.349
26707573	Autophagy-associated proteins BAG3 and p62 in testicular cancer.	Oncol Rep	2016 Mar	Bartsch G	doi: 10.3892/or.2015.4505
26100943	Knockdown of BAG3 sensitizes bladder cancer cells to treatment with the BH3 mimetic ABT-737.	World J Urol	2016 Feb	Mani J	doi: 10.1007/s00345-015-1616-2
21451574	BAG3 is required for IKKα nuclear translocation and emergence of castration resistant prostate cancer.	Cell Death Dis	2011 Mar 31	Ammirante M	doi: 10.1038/cddis.2011.23.
23341456	The stress protein BAG3 stabilizes Mcl-1 protein and promotes survival of cancer cells and resistance to antagonist ABT-737.	J Biol Chem	2013 Mar 8	Boiani M	doi: 10.1074/jbc.M112.414177
25968616	Bis Expression in Patients with Surgically Resected Lung Cancer and its Clinical Significance.	Ann Surg Oncol	2015 Dec	Yeo CD	doi: 10.1245/s10434-015-4576-2
21561597	BAG3 protein is overexpressed in human glioblastoma and is a potential target for therapy.	Am J Pathol	2011 Jun	Festa M	doi: 10.1016/j.ajpath.2011.02.002
21971866	Bag3 promotes resistance to apoptosis through Bcl-2 family members in non-small cell lung cancer.	Oncol Rep	2012 Jan	Zhang Y	doi: 10.3892/or.2011.1486
23108398	PKC??-mediated phosphorylation of BAG3 at Ser187 site induces epithelial-mesenchymal transition and enhances invasiveness in thyroid cancer FRO cells.	Oncogene	2013 Sep 19	Li N	doi: 10.1038/onc.2012.466
24997994	Proteomic analysis reveals a role for Bcl2-associated athanogene 3 and major vault protein in resistance to apoptosis in senescent cells by regulating ERK1/2 activation.	Mol Cell Proteomics	2015 Jan	Pasillas MP	doi: 10.1074/mcp.M114.037697
20232307	Characterization of BAG3 cleavage during apoptosis of pancreatic cancer cells.	J Cell Physiol	2010 Jul	Wang HQ	doi: 10.1002/jcp.22097.
27120977	BAG3-mediated Mcl-1 stabilization contributes to drug resistance via interaction with USP9X in ovarian cancer.	Int J Oncol	2016 Jul	Habata S	doi: 10.3892/ijo.2016.3494
27922674	2'-Hydroxycinnamaldehyde induces apoptosis through HSF1-mediated BAG3 expression.	Int J Oncol	2017 Jan	Nguyen HA	doi: 10.3892/ijo.2016.3790
27414463	BAG3 Protein Is Over-Expressed in Endometrioid Endometrial Adenocarcinomas.	J Cell Physiol	2017 Feb	Esposito V	doi: 10.1002/jcp.25489
28624440	BAG3 promotes proliferation of ovarian cancer cells via post-transcriptional regulation of Skp2 expression.	Biochim Biophys Acta Mol Cell Res	2017 Oct	Yan J	doi: 10.1016/j.bbamcr.2017.06.004
29114069	BAG3 directly stabilizes Hexokinase 2 mRNA and promotes aerobic glycolysis in pancreatic cancer cells.	J Cell Biol	2017 Dec 4	An MX	doi: 10.1083/jcb.201701064
27145367	BIS-mediated STAT3 stabilization regulates glioblastoma stem cell-like phenotypes.	Oncotarget	2016 Jun 7	Im CN	doi: 10.18632/oncotarget.9039.
30194150	Implication of BIS in the Migration and Invasion of A549 Non-small Cell Lung Cancer Cells.	Anticancer Res	2018 Sep	Lee J	doi: 10.21873/anticanres.12825.
29068469	BAG3-dependent expression of Mcl-1 confers resistance of mutant KRAS colon cancer cells to the HSP90 inhibitor AUY922.	Mol Carcinog	2018 Feb	Wang CY	doi: 10.1002/mc.22755
29295729	miR-206 Inhibits Cell Proliferation, Migration, and Invasion by Targeting BAG3 in Human Cervical Cancer.	Oncol Res	2018 Jul 5	Wang Y	doi: 10.3727/096504017X15143731031009
30514177	BAG3 contributes to HGF-mediated cell proliferation, migration, and invasion via the Egr1 pathway in gastric cancer.	Tumori	2019 Feb	Lee JC	doi: 10.1177/0300891618811274

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
BLCA	chr10	119672392	Silent	rs138078305	N215N	0.22
BLCA	chr10	119651749	Missense_Mutation	novel	G25E	0.35
BLCA	chr10	119651678	Translation_Start_Site	NA	M1?	0.57
BRCA	chr10	119669959	Missense_Mutation	rs747274078	P97S	0.33
BRCA	chr10	119672320	Silent	rs753386051	S191S	0.34
CESC	chr10	119670106	Nonsense_Mutation	NA	Q146*	0.11
CESC	chr10	119672384	Missense_Mutation	novel	E213K	0.34
CESC	chr10	119676645	Missense_Mutation	novel	V364A	0.48
COAD	chr10	119676922	Silent	NA	E456E	0.49
COAD	chr10	119676844	Missense_Mutation	novel	E430D	0.17
COAD	chr10	119672627	Missense_Mutation	rs144585878	R294C	0.44
COAD	chr10	119651742	Frame_Shift_Del	NA	*G25Dfs186**	0.23
COAD	chr10	119651682	Missense_Mutation	NA	A3T	0.16
COAD	chr10	119670049	Missense_Mutation	NA	A127T	0.18
COAD	chr10	119651686	Missense_Mutation	NA	A4V	0.4
COAD	chr10	119677084	Silent	NA	L510L	0.1
COAD	chr10	119670032	Missense_Mutation	NA	R121Q	0.2
COAD	chr10	119669928	Silent	NA	Y86Y	0.37
ESCA	chr10	119677353	3'UTR	novel		0.38
GBM	chr10	119670047	Missense_Mutation	novel	A126E	0.66
HNSC	chr10	119676931	Silent	novel	T459T	0.21
HNSC	chr10	119651815	Missense_Mutation	novel	T47I	0.59
HNSC	chr10	119651792	Silent	novel	F39F	0.35
HNSC	chr10	119670038	Missense_Mutation	rs199991063	R123Q	0.11
HNSC	chr10	119677155	Missense_Mutation	novel	K534R	0.25
HNSC	chr10	119677205	Nonsense_Mutation	novel	Q551*	0.34
HNSC	chr10	119670077	Missense_Mutation	novel	S136L	0.11
KICH	chr10	119672397	Missense_Mutation	novel	T217I	0.06
LAML	chr10	119676905	Missense_Mutation	novel	Y451D	0.08
LGG	chr10	119669911	Missense_Mutation	NA	E81K	0.63
LGG	chr10	119672602	Silent	rs147259596	T285T	0.1
LIHC	chr10	119651661	5'UTR	novel		0.35
LUAD	chr10	119672354	Missense_Mutation	NA	R203W	0.16
LUAD	chr10	119672574	Missense_Mutation	novel	R276L	0.13
LUAD	chr10	119672357	Missense_Mutation	novel	G204W	0.16
LUSC	chr10	119676859	Silent	NA	L435L	0.17
LUSC	chr10	119677347	3'UTR	novel		0.32
LUSC	chr10	119651627	5'UTR	novel		0.63
LUSC	chr10	119672645	Missense_Mutation	rs78439745	D300N	0.17
OV	chr10	119670085	Missense_Mutation	rs556465096	R139W	0.42
OV	chr10	119672601	Missense_Mutation	rs375650805	T285M	0.42
OV	chr10	119677450	3'UTR	novel		0.44
OV	chr10	119676854	Missense_Mutation	NA	G434R	0.63
PAAD	chr10	119669960	Missense_Mutation	novel	P97H	0.06
PAAD	chr10	119670139	Missense_Mutation	novel	A157T	0.15
READ	chr10	119677172	Missense_Mutation	novel	G540R	0.09
SKCM	chr10	119672539	Silent	NA	S264S	0.26
SKCM	chr10	119669938	Nonsense_Mutation	NA	R90*	0.36
SKCM	chr10	119676952	Silent	novel	D466D	0.36
SKCM	chr10	119669968	Missense_Mutation	NA	H100Y	0.21
SKCM	chr10	119676711	Missense_Mutation	NA	S386F	0.28
SKCM	chr10	119672325	Missense_Mutation	rs752722473	R193K	0.18
SKCM	chr10	119672383	Missense_Mutation	NA	H212Q	0.37
STAD	chr10	119651742	Frame_Shift_Del	NA	*G25Dfs186**	0.44
STAD	chr10	119676610	Silent	NA	S352S	0.11
STAD	chr10	119670056	Missense_Mutation	NA	A129V	0.07
STAD	chr10	119677309	3'UTR	novel		0.29
STAD	chr10	119676909	Missense_Mutation	novel	L452P	0.15
STAD	chr10	119651719	Missense_Mutation	NA	G15D	0.34
STAD	chr10	119676587	Nonsense_Mutation	NA	E345*	0.42
STAD	chr10	119669901	Silent	rs143752613	P77P	0.24
STAD	chr10	119651741	Frame_Shift_Ins	rs772351208	*G25Rfs33**	0.37
STAD	chr10	119672255	Missense_Mutation	rs200479768	R170W	0.37
STAD	chr10	119672283	In_Frame_Ins	novel	S184_S185dup	0.24
STAD	chr10	119676967	Missense_Mutation	NA	E471D	0.18
STAD	chr10	119669976	Silent	rs202006167	G102G	0.14
STAD	chr10	119676936	Missense_Mutation	NA	E461V	0.11
STAD	chr10	119676873	Missense_Mutation	NA	D440G	0.13
UCEC	chr10	119670137	Missense_Mutation	rs572038196	A156V	0.42
UCEC	chr10	119651710	Missense_Mutation	novel	V12A	0.19
UCEC	chr10	119670140	Missense_Mutation	rs541080567	A157V	0.38
UCEC	chr10	119676917	Missense_Mutation	rs397516881	E455K	0.25
UCEC	chr10	119672328	Missense_Mutation	novel	S194N	0.64
UCEC	chr10	119676903	Missense_Mutation	novel	K450R	0.09
UCEC	chr10	119672529	Missense_Mutation	rs746454994	R261Q	0.35
UCEC	chr10	119677341	3'UTR	novel		0.44
UCEC	chr10	119672645	Missense_Mutation	rs78439745	D300N	0.27
UCEC	chr10	119670071	Missense_Mutation	novel	S134F	0.57
UCEC	chr10	119672581	Silent	novel	G278G	0.14
UCEC	chr10	119677001	Missense_Mutation	rs570294713	G483S	0.18
UCEC	chr10	119672628	Missense_Mutation	rs151335530	R294H	0.18
UCEC	chr10	119676812	Missense_Mutation	NA	P420T	0.14
UCEC	chr10	119672465	Missense_Mutation	novel	Y240H	0.55
UCEC	chr10	119670072	Silent	novel	S134S	0.24
UCEC	chr10	119677355	3'UTR	novel		0.42
UCEC	chr10	119677223	Missense_Mutation	novel	A557T	0.24
UCEC	chr10	119670047	Missense_Mutation	novel	A126V	0.17
UCEC	chr10	119672255	Missense_Mutation	rs200479768	R170W	0.31
UCEC	chr10	119672529	Missense_Mutation	rs746454994	R261Q	0.36
UCEC	chr10	119677314	3'UTR	rs773925708		0.35
UCEC	chr10	119672644	Silent	rs763915884	V299V	0.23
UCEC	chr10	119677238	Missense_Mutation	novel	P562S	0.2
UCEC	chr10	119676527	Missense_Mutation	novel	P325S	0.43
UCEC	chr10	119672622	Missense_Mutation	rs748451757	P292L	0.2
UCEC	chr10	119672525	Frame_Shift_Ins	novel	*L260Hfs59**	0.26
UCEC	chr10	119676639	Missense_Mutation	rs200812717	V362A	0.08
UCEC	chr10	119672452	Silent	rs141328836	A235A	0.42
UCEC	chr10	119677280	Nonstop_Mutation	novel	576Qext15	0.21
UCEC	chr10	119677178	Missense_Mutation	NA	A542T	0.37
UCEC	chr10	119651706	Nonsense_Mutation	novel	Q11*	0.26
UCEC	chr10	119676755	Missense_Mutation	novel	A401T	0.16
UCEC	chr10	119676976	Silent	rs727505000	A474A	0.31
UVM	chr10	119669901	Silent	rs143752613	P77P	0.25

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	DEL	0.1	0.19593
CHOL	DEL	0.2778	0.048655
COAD	DEL	0.1552	9.4741e-07
LGG	DEL	0.2632	4.3789e-20
LIHC	DEL	0.2514	5.7505e-06
MESO	DEL	0.2989	0.00015289
OV	DEL	0.3057	5.3759e-12
PAAD	DEL	0.1141	0.169
READ	DEL	0.2061	0.014135
THYM	DEL	0.0325	0.10563
UCS	DEL	0.2679	0.1218

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.00094	Kaplan-Meier Survival Analysis
MESO	0.0055	Kaplan-Meier Survival Analysis
HNSC	0.034	Kaplan-Meier Survival Analysis
ESCA	0.025	Kaplan-Meier Survival Analysis
COAD	0.026	Kaplan-Meier Survival Analysis
PAAD	0.0024	Kaplan-Meier Survival Analysis
BLCA	0.0068	Kaplan-Meier Survival Analysis
READ	0.031	Kaplan-Meier Survival Analysis
LAML	0.0011	Kaplan-Meier Survival Analysis
GBM	0.012	Kaplan-Meier Survival Analysis
LIHC	0.0053	Kaplan-Meier Survival Analysis
CHOL	0.045	Kaplan-Meier Survival Analysis
OV	0.016	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000151929 (Gene tree)
Gene ID: 9531
Gene Symbol: BAG3
Alias: N
Full Name: BCL2 associated athanogene 3
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 26,473 bases
Position: chr10:119,651,347-119,677,819
Accession: 939
RBP type: non-canonical RBP
Summary: BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
31317183	Dilated cardiomyopathy and arrhythmogenic left ventricular cardiomyopathy: a comprehensive genotype-imaging phenotype study.	Eur Heart J Cardiovasc Imaging	2019 Jul 16	Augusto JB	doi: 10.1093/ehjci/jez188
29114069	BAG3 directly stabilizes Hexokinase 2 mRNA and promotes aerobic glycolysis in pancreatic cancer cells.	J Cell Biol	2017 Dec 4	An MX	doi: 10.1083/jcb.201701064
30154469	BAG3 regulates stability of IL-8 mRNA via interplay between HuR and miR-4312 in PDACs.	Cell Death Dis	2018 Aug 28	Li C	doi: 10.1038/s41419-018-0874-5.
20018251	The co-chaperone BAG3 interacts with the cytosolic chaperonin CCT: new hints for actin folding.	Int J Biochem Cell Biol	2010 May	Fontanella B	doi: 10.1016/j.biocel.2009.12.008
26512958	A novel miR-371a-5p-mediated pathway, leading to BAG3 upregulation in cardiomyocytes in response to epinephrine, is lost in Takotsubo cardiomyopathy.	Cell Death Dis	2015 Oct 29	d'Avenia M	doi: 10.1038/cddis.2015.280.

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000369085	BAG3-201	2571	XM_005270287	ENSP00000358081	575 (aa)	XP_005270344	O95817
ENST00000450186	BAG3-202	1146	-	ENSP00000410036	325 (aa)	-	C9JFK9

Gene Model

Click here to download ENSG00000151929's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000151929	Stroke	9.6181078E-004	19369658
ENSG00000151929	Cardiomyopathy, Dilated	4E-12	21459883

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000151929	rs2234962	10	119670121	?	Idiopathic dilated cardiomyopathy	21459883	[1.22-1.89]	1.52	EFO_0000407
ENSG00000151929	rs7095308	10	119666800	?	Systolic blood pressure	30595370			EFO_0006335
ENSG00000151929	rs17617337	10	119667372	C	Diastolic blood pressure	27841878	unit increase	0.172	EFO_0006336
ENSG00000151929	rs2234962	10	119670121	?	Lung function (FEV1/FVC)	30595370			EFO_0004713

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000151929's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000151929	BAG3	100	83.305	ENSMUSG00000030847	Bag3	100	83.305	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000045	autophagosome assembly	-	IEA	Process
GO:0000774	adenyl-nucleotide exchange factor activity	20060297.24318877.	IDA	Function
GO:0001725	stress fiber	-	IEA	Component
GO:0005515	protein binding	16189514.19229298.21044950.21516116.22366786.23434281.24318877.24510904.25036637.25277244.25416956.26159920.26496610.28144995.	IPI	Function
GO:0005634	nucleus	26159920.	IDA	Component
GO:0005737	cytoplasm	26159920.	IDA	Component
GO:0005829	cytosol	10597216.	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0005886	plasma membrane	-	IDA	Component
GO:0006457	protein folding	9873016.	NAS	Process
GO:0007420	brain development	-	IEA	Process
GO:0008565	protein transporter activity	21681022.	TAS	Function
GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	10597216.	IDA	Process
GO:0010664	negative regulation of striated muscle cell apoptotic process	19085932.	IMP	Process
GO:0016235	aggresome	21681022.	TAS	Component
GO:0021510	spinal cord development	-	IEA	Process
GO:0030018	Z disc	-	IEA	Component
GO:0034605	cellular response to heat	26159920.	IDA	Process
GO:0034620	cellular response to unfolded protein	18006506.	IMP	Process
GO:0042307	positive regulation of protein import into nucleus	26159920.	IMP	Process
GO:0043005	neuron projection	-	IEA	Component
GO:0043066	negative regulation of apoptotic process	10597216.	NAS	Process
GO:0044877	protein-containing complex binding	-	IEA	Function
GO:0045296	cadherin binding	25468996.	HDA	Function
GO:0045505	dynein intermediate chain binding	21252941.	NAS	Function
GO:0046716	muscle cell cellular homeostasis	19085932.	IMP	Process
GO:0046827	positive regulation of protein export from nucleus	26159920.	IMP	Process
GO:0050790	regulation of catalytic activity	-	IEA	Process
GO:0050821	protein stabilization	18006506.	IDA	Process
GO:0051087	chaperone binding	18006506.	IPI	Function
GO:0061684	chaperone-mediated autophagy	-	IEA	Process
GO:0070842	aggresome assembly	21681022.	TAS	Process
GO:0071260	cellular response to mechanical stimulus	-	IEA	Process
GO:0072321	chaperone-mediated protein transport	21681022.	TAS	Process
GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	-	IEA	Process
GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress	26159920.	IMP	Process
GO:0098840	protein transport along microtubule	21681022.	TAS	Process
GO:0101031	chaperone complex	18006506.	IDA	Component
GO:1900034	regulation of cellular response to heat	-	TAS	Process
GO:1903215	negative regulation of protein targeting to mitochondrion	-	IEA	Process
GO:1905337	positive regulation of aggrephagy	18006506.	IMP	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.