EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
18535175	Regulation of Skp2-p27 axis by the Cdh1/anaphase-promoting complex pathway in colorectal tumorigenesis.	Am J Pathol	2008 Jul	Fujita T	doi: 10.2353/ajpath.2008.070957
26329581	The E3 ligase APC/C(Cdh1) promotes ubiquitylation-mediated proteolysis of PAX3 to suppress melanocyte proliferation and melanoma growth.	Sci Signal	2015 Sep 1	Cao J	doi: 10.1126/scisignal.aab1995.
23637229	Regulation of Rad17 protein turnover unveils an impact of Rad17-APC cascade in breast carcinogenesis and treatment.	J Biol Chem	2013 Jun 21	Zhou Z	doi: 10.1074/jbc.M113.456962

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
BLCA	chr2	111824976	Missense_Mutation	novel	M934I	0.28
BLCA	chr2	111863705	Missense_Mutation	NA	S341L	0.14
BLCA	chr2	111784349	Missense_Mutation	novel	L1657F	0.22
BLCA	chr2	111873400	Missense_Mutation	novel	E146Q	0.09
BLCA	chr2	111831374	Missense_Mutation	NA	Q846P	0.38
BLCA	chr2	111850847	Missense_Mutation	rs551412961	R527W	0.36
BLCA	chr2	111833303	Missense_Mutation	rs756261861	K798T	0.47
BLCA	chr2	111847813	Missense_Mutation	novel	D568G	0.48
BLCA	chr2	111873369	Missense_Mutation	novel	S156I	0.46
BLCA	chr2	111784334	Missense_Mutation	NA	L1662I	0.12
BLCA	chr2	111792435	Missense_Mutation	novel	G1547S	0.22
BLCA	chr2	111808990	Frame_Shift_Del	novel	*T1264Qfs14**	0.15
BLCA	chr2	111863791	Nonsense_Mutation	novel	*D312Efs5**	0.07
BLCA	chr2	111834781	Missense_Mutation	NA	S736L	0.2
BLCA	chr2	111864826	Missense_Mutation	novel	L271V	0.2
BLCA	chr2	111850854	Silent	rs753530824	T524T	0.4
BLCA	chr2	111850854	Silent	novel	T524T	0.51
BLCA	chr2	111847767	Nonsense_Mutation	novel	Y583*	0.27
BLCA	chr2	111792485	Missense_Mutation	NA	S1530L	0.18
BRCA	chr2	111831299	Missense_Mutation	rs757156864	R871K	0.36
BRCA	chr2	111834783	Silent	NA	A735A	0.46
BRCA	chr2	111831348	Missense_Mutation	novel	E855K	0.07
BRCA	chr2	111792419	Missense_Mutation	NA	Y1552C	0.54
BRCA	chr2	111825013	Missense_Mutation	NA	S922F	0.06
BRCA	chr2	111838503	Missense_Mutation	novel	E684Q	0.28
BRCA	chr2	111784373	Nonsense_Mutation	novel	E1649*	0.16
BRCA	chr2	111868053	Missense_Mutation	NA	E219K	0.17
BRCA	chr2	111873625	Missense_Mutation	NA	E139Q	0.22
BRCA	chr2	111850877	Missense_Mutation	NA	P517T	0.16
BRCA	chr2	111809159	Missense_Mutation	NA	G1207E	0.17
BRCA	chr2	111769344	Missense_Mutation	NA	L1928V	0.15
BRCA	chr2	111802432	Missense_Mutation	novel	L1406P	0.38
BRCA	chr2	111772377	Missense_Mutation	novel	P1895S	0.13
CESC	chr2	111782408	Silent	novel	Q1721Q	0.38
CESC	chr2	111850814	Missense_Mutation	rs148969655	P538A	0.2
CESC	chr2	111838443	Missense_Mutation	novel	D704N	0.08
CESC	chr2	111831320	Missense_Mutation	rs201476913	P864L	0.38
CESC	chr2	111809123	Frame_Shift_Ins	novel	*T1219Kfs68**	0.12
CESC	chr2	111850829	Missense_Mutation	novel	D533H	0.12
CESC	chr2	111880721	Silent	NA	L35L	0.47
CESC	chr2	111843431	Missense_Mutation	rs772338494	R674H	0.32
CESC	chr2	111863896	Splice_Site	novel	X278_splice	0.22
CESC	chr2	111822510	Missense_Mutation	novel	S968L	0.2
CESC	chr2	111792459	Missense_Mutation	novel	C1539R	0.76
COAD	chr2	111769401	Missense_Mutation	novel	T1909S	0.22
COAD	chr2	111834642	Silent	NA	G782G	0.33
COAD	chr2	111785457	Missense_Mutation	novel	R1607Q	0.28
COAD	chr2	111834866	Missense_Mutation	novel	E708K	0.41
COAD	chr2	111858378	Missense_Mutation	novel	K429T	0.29
COAD	chr2	111784370	Nonsense_Mutation	rs749616796	E1650*	0.08
COAD	chr2	111864949	Missense_Mutation	NA	L230I	0.16
COAD	chr2	111843593	Missense_Mutation	rs144034109	T620M	0.26
COAD	chr2	111802487	Nonsense_Mutation	novel	R1388*	0.12
COAD	chr2	111856833	Missense_Mutation	NA	V471A	0.09
COAD	chr2	111803760	Missense_Mutation	novel	R1335H	0.26
COAD	chr2	111856857	Missense_Mutation	NA	K463T	0.18
COAD	chr2	111769349	Missense_Mutation	novel	R1926Q	0.32
COAD	chr2	111873216	Intron	novel		0.32
COAD	chr2	111880820	Silent	rs747691768	S2S	0.37
COAD	chr2	111794825	Missense_Mutation	novel	T1456S	0.47
ESCA	chr2	111873083	Intron	novel		0.3
ESCA	chr2	111772421	Nonsense_Mutation	novel	S1880*	0.29
ESCA	chr2	111847767	Nonsense_Mutation	novel	Y583*	0.4
GBM	chr2	111880705	Nonsense_Mutation	novel	Q41*	0.1
GBM	chr2	111802480	Missense_Mutation	NA	P1390H	0.35
GBM	chr2	111862512	Missense_Mutation	novel	R380I	0.17
GBM	chr2	111834846	Missense_Mutation	novel	D714E	0.17
HNSC	chr2	111769288	3'UTR	rs760041337		0.4
HNSC	chr2	111880672	Missense_Mutation	rs752960301	D52N	0.13
HNSC	chr2	111821381	Missense_Mutation	novel	E1022K	0.53
HNSC	chr2	111782433	Missense_Mutation	novel	M1713T	0.22
HNSC	chr2	111850902	Missense_Mutation	novel	K508N	0.17
HNSC	chr2	111785375	Silent	novel	L1634L	0.4
HNSC	chr2	111863848	Silent	novel	Q293Q	0.18
HNSC	chr2	111850888	Missense_Mutation	novel	G513V	0.29
HNSC	chr2	111784324	Missense_Mutation	novel	Q1665L	0.21
HNSC	chr2	111880746	Missense_Mutation	novel	H27R	0.11
KIRC	chr2	111873054	Intron	novel		0.44
KIRC	chr2	111782394	Missense_Mutation	NA	R1726T	0.38
KIRC	chr2	111868077	Missense_Mutation	NA	F211V	0.3
KIRP	chr2	111880658	Silent	novel	G56G	0.3
KIRP	chr2	111850773	Splice_Region	novel		0.45
KIRP	chr2	111850827	Silent	rs763490262	D533D	0.24
LGG	chr2	111880721	Missense_Mutation	novel	L35F	0.16
LGG	chr2	111778735	Silent	novel	L1775L	0.12
LGG	chr2	111838464	Missense_Mutation	novel	R697G	0.4
LIHC	chr2	111772416	Frame_Shift_Del	novel	L1872*	0.07
LIHC	chr2	111802458	Frame_Shift_Del	novel	*F1398Lfs2**	0.25
LIHC	chr2	111792456	Missense_Mutation	NA	R1540C	0.39
LIHC	chr2	111843579	Missense_Mutation	novel	I625V	0.39
LIHC	chr2	111873015	Intron	novel		0.15
LUAD	chr2	111788234	Missense_Mutation	novel	R1600L	0.1
LUAD	chr2	111847146	Missense_Mutation	NA	S615C	0.13
LUAD	chr2	111788319	Missense_Mutation	novel	Y1572H	0.08
LUAD	chr2	111782485	Missense_Mutation	rs755821664	V1696F	0.16
LUAD	chr2	111782486	Silent	rs777518303	G1695G	0.18
LUAD	chr2	111847814	Missense_Mutation	NA	D568N	0.08
LUAD	chr2	111858306	Missense_Mutation	NA	R453L	0.26
LUAD	chr2	111834696	Missense_Mutation	novel	F764L	0.12
LUAD	chr2	111868058	Missense_Mutation	novel	L217P	0.06
LUAD	chr2	111788286	Missense_Mutation	rs760585060	A1583T	0.11
LUAD	chr2	111788235	Missense_Mutation	rs779157640	R1600W	0.29
LUAD	chr2	111843530	Nonsense_Mutation	novel	W641*	0.28
LUAD	chr2	111831340	Missense_Mutation	NA	M857I	0.08
LUAD	chr2	111809012	Missense_Mutation	novel	G1256V	0.28
LUAD	chr2	111809013	Missense_Mutation	novel	G1256C	0.26
LUSC	chr2	111792537	Nonsense_Mutation	NA	E1513*	0.33
LUSC	chr2	111863739	Missense_Mutation	NA	R330C	0.11
LUSC	chr2	111847185	Missense_Mutation	NA	G602D	0.68
LUSC	chr2	111864889	Missense_Mutation	novel	N250Y	0.15
LUSC	chr2	111778750	Silent	NA	L1770L	0.26
LUSC	chr2	111880739	Missense_Mutation	novel	K29N	0.23
LUSC	chr2	111821239	Missense_Mutation	novel	R1069I	0.5
LUSC	chr2	111878871	Missense_Mutation	novel	G105V	0.25
LUSC	chr2	111784365	Missense_Mutation	NA	L1651F	0.07
LUSC	chr2	111834644	Missense_Mutation	novel	G782R	0.25
LUSC	chr2	111821252	Missense_Mutation	novel	E1065K	0.59
LUSC	chr2	111782387	Silent	NA	S1728S	0.1
LUSC	chr2	111808966	Silent	novel	E1271E	0.44
LUSC	chr2	111858306	Missense_Mutation	rs753241990	R453H	0.24
OV	chr2	111808999	Silent	NA	V1260V	0.48
OV	chr2	111809139	Missense_Mutation	NA	A1214S	0.1
OV	chr2	111772382	Missense_Mutation	novel	S1893C	0.13
PAAD	chr2	111843426	Missense_Mutation	novel	A676T	0.19
PAAD	chr2	111880707	Missense_Mutation	novel	R40H	0.21
PRAD	chr2	111785409	Missense_Mutation	novel	D1623A	0.36
PRAD	chr2	111847148	Silent	rs761627503	T614T	0.35
PRAD	chr2	111862477	Missense_Mutation	rs540910667	N392D	0.18
PRAD	chr2	111847808	Missense_Mutation	novel	L570F	0.05
PRAD	chr2	111803831	Silent	novel	S1311S	0.36
PRAD	chr2	111873352	Missense_Mutation	novel	H162Y	0.29
READ	chr2	111834706	Missense_Mutation	NA	A761V	0.18
READ	chr2	111794885	Missense_Mutation	NA	E1436K	0.47
READ	chr2	111783925	Missense_Mutation	novel	D1679Y	0.18
SARC	chr2	111778754	Missense_Mutation	novel	D1769V	0.49
SARC	chr2	111858347	Missense_Mutation	novel	Q439H	0.3
SKCM	chr2	111856814	Silent	NA	K477K	0.08
SKCM	chr2	111863887	Missense_Mutation	NA	N280K	0.54
SKCM	chr2	111792549	Missense_Mutation	novel	P1509S	0.18
SKCM	chr2	111834794	Missense_Mutation	novel	P732S	0.16
SKCM	chr2	111863739	Missense_Mutation	NA	R330C	0.28
SKCM	chr2	111834845	Missense_Mutation	NA	Y715H	0.21
SKCM	chr2	111778764	Missense_Mutation	novel	E1766K	0.22
SKCM	chr2	111862566	Missense_Mutation	NA	S362F	0.38
SKCM	chr2	111847843	Missense_Mutation	NA	P558L	0.33
SKCM	chr2	111821435	Missense_Mutation	novel	P1004S	0.27
SKCM	chr2	111772355	Missense_Mutation	NA	P1902L	0.11
SKCM	chr2	111862587	Missense_Mutation	NA	S355F	0.16
SKCM	chr2	111809004	Missense_Mutation	novel	L1259F	0.18
SKCM	chr2	111838445	Missense_Mutation	novel	S703F	0.29
SKCM	chr2	111778752	Missense_Mutation	NA	L1770F	0.18
SKCM	chr2	111834674	Missense_Mutation	rs750827131	E772K	0.29
SKCM	chr2	111778705	Silent	NA	E1785E	0.12
SKCM	chr2	111782496	Missense_Mutation	novel	S1692C	0.38
SKCM	chr2	111784337	Missense_Mutation	NA	H1661Y	0.35
SKCM	chr2	111778752	Missense_Mutation	NA	L1770F	0.21
SKCM	chr2	111856868	Silent	NA	E459E	0.11
SKCM	chr2	111856861	Missense_Mutation	rs769251816	D462N	0.19
SKCM	chr2	111863787	Missense_Mutation	rs746437990	P314S	0.24
SKCM	chr2	111821259	Silent	NA	F1062F	0.22
SKCM	chr2	111809099	Missense_Mutation	NA	L1227H	0.14
SKCM	chr2	111784346	Missense_Mutation	NA	P1658S	0.11
SKCM	chr2	111824997	Silent	NA	A927A	0.08
SKCM	chr2	111850881	Silent	NA	P515P	0.16
SKCM	chr2	111784346	Missense_Mutation	NA	P1658S	0.19
SKCM	chr2	111778677	Nonsense_Mutation	novel	Q1795*	0.14
SKCM	chr2	111772393	Silent	rs772269461	L1889L	0.46
SKCM	chr2	111788259	Missense_Mutation	NA	F1592L	0.27
SKCM	chr2	111778764	Missense_Mutation	novel	E1766K	0.1
SKCM	chr2	111809138	Missense_Mutation	NA	A1214V	0.2
SKCM	chr2	111778764	Missense_Mutation	novel	E1766K	0.38
SKCM	chr2	111834765	In_Frame_Del	novel	K739_E741del	0.38
SKCM	chr2	111864920	Silent	novel	V239V	0.24
SKCM	chr2	111847729	Missense_Mutation	novel	T596I	0.21
SKCM	chr2	111880753	Nonsense_Mutation	rs13023605	R25*	0.17
SKCM	chr2	111850793	Missense_Mutation	NA	L545F	0.46
SKCM	chr2	111872711	Missense_Mutation	NA	V177A	0.47
SKCM	chr2	111862491	Missense_Mutation	novel	P387L	0.32
STAD	chr2	111825161	Frame_Shift_Ins	novel	*Q904Pfs13**	0.11
STAD	chr2	111821297	Missense_Mutation	novel	N1050D	0.22
STAD	chr2	111788286	Missense_Mutation	rs760585060	A1583T	0.16
STAD	chr2	111843452	Missense_Mutation	NA	M667T	0.32
STAD	chr2	111863734	Silent	NA	S331S	0.37
STAD	chr2	111825809	Missense_Mutation	NA	E891A	0.26
STAD	chr2	111880624	Missense_Mutation	novel	E68K	0.41
STAD	chr2	111862452	Missense_Mutation	rs368906308	T400M	0.19
STAD	chr2	111785394	Missense_Mutation	rs751341287	T1628M	0.2
STAD	chr2	111821313	Silent	novel	A1044A	0.34
STAD	chr2	111863790	Missense_Mutation	NA	S313P	0.16
STAD	chr2	111794880	Silent	novel	N1437N	0.42
STAD	chr2	111850900	Missense_Mutation	NA	V509A	0.13
STAD	chr2	111863858	Frame_Shift_Del	NA	*G290Efs26**	0.32
STAD	chr2	111821333	Nonsense_Mutation	novel	R1038*	0.21
STAD	chr2	111821313	Silent	novel	A1044A	0.23
TGCT	chr2	111772393	Silent	rs772269461	L1889L	0.12
UCEC	chr2	111769359	Frame_Shift_Del	novel	*M1923Cfs7**	0.33
UCEC	chr2	111858307	Missense_Mutation	rs567800751	R453C	0.31
UCEC	chr2	111872856	Intron	novel		0.5
UCEC	chr2	111873176	Intron	novel		0.39
UCEC	chr2	111778705	Missense_Mutation	NA	E1785D	0.22
UCEC	chr2	111850902	Silent	NA	K508K	0.22
UCEC	chr2	111872669	Missense_Mutation	NA	R191Q	0.25
UCEC	chr2	111784399	Missense_Mutation	rs533459247	G1640D	0.09
UCEC	chr2	111873380	Silent	novel	C152C	0.31
UCEC	chr2	111778752	Missense_Mutation	NA	L1770I	0.21
UCEC	chr2	111821259	Silent	NA	F1062F	0.36
UCEC	chr2	111769391	Missense_Mutation	novel	A1912D	0.54
UCEC	chr2	111821264	Missense_Mutation	novel	E1061K	0.09
UCEC	chr2	111825017	Missense_Mutation	novel	T921A	0.06
UCEC	chr2	111872680	Silent	novel	L187L	0.4
UCEC	chr2	111782369	Splice_Region	NA	K1734K	0.42
UCEC	chr2	111843578	Missense_Mutation	novel	I625N	0.1
UCEC	chr2	111788280	Missense_Mutation	NA	L1585I	0.18
UCEC	chr2	111862494	Missense_Mutation	novel	S386Y	0.06
UCEC	chr2	111788250	Missense_Mutation	novel	H1595Y	0.16
UCEC	chr2	111843431	Missense_Mutation	rs772338494	R674H	0.42
UCEC	chr2	111847818	Silent	novel	L566L	0.33
UCEC	chr2	111772441	Silent	novel	S1873S	0.47
UCEC	chr2	111778692	Missense_Mutation	novel	Y1790H	0.28
UCEC	chr2	111873373	Nonsense_Mutation	novel	Q155*	0.56
UCEC	chr2	111783926	Silent	NA	I1678I	0.74
UCEC	chr2	111784360	Missense_Mutation	NA	A1653V	0.19
UCEC	chr2	111822525	Missense_Mutation	novel	R963H	0.37
UCEC	chr2	111794859	Silent	rs756979171	I1444I	0.27
UCEC	chr2	111783931	Missense_Mutation	novel	L1677F	0.16
UCEC	chr2	111843432	Missense_Mutation	rs776057720	R674C	0.18
UCEC	chr2	111782462	Silent	rs373638147	A1703A	0.09
UCEC	chr2	111769288	3'UTR	rs760041337		0.38
UCEC	chr2	111778737	Missense_Mutation	novel	L1775F	0.38
UCEC	chr2	111809066	Frame_Shift_Del	novel	*P1238Qfs40**	0.05
UCEC	chr2	111868033	Silent	NA	C225C	0.17
UCEC	chr2	111800871	Missense_Mutation	novel	T1408P	0.29
UCEC	chr2	111792504	Missense_Mutation	novel	A1524T	0.09
UCEC	chr2	111863895	Nonsense_Mutation	novel	E278*	0.11
UCEC	chr2	111872856	Intron	novel		0.21
UCEC	chr2	111831339	Missense_Mutation	rs781660125	P858S	0.08
UCEC	chr2	111873389	Frame_Shift_Del	novel	*K149Nfs16**	0.28
UCEC	chr2	111864944	Frame_Shift_Del	novel	*F231Lfs10**	0.4
UCEC	chr2	111834697	Frame_Shift_Del	NA	*F764Sfs12**	0.35
UCEC	chr2	111838494	Missense_Mutation	novel	L687I	0.37
UCEC	chr2	111873279	Intron	novel		0.3
UCEC	chr2	111782468	Silent	novel	L1701L	0.16
UCEC	chr2	111785461	Missense_Mutation	novel	L1606I	0.52
UCEC	chr2	111788313	Missense_Mutation	novel	L1574V	0.2
UCEC	chr2	111822586	Missense_Mutation	novel	D943Y	0.43
UCEC	chr2	111862465	Missense_Mutation	novel	L396I	0.48
UCEC	chr2	111782369	Missense_Mutation	novel	K1734N	0.3
UCEC	chr2	111862480	Missense_Mutation	NA	S391A	0.1
UCEC	chr2	111864905	Missense_Mutation	NA	M244I	0.26
UCEC	chr2	111833277	Missense_Mutation	novel	Y807H	0.3
UCEC	chr2	111843417	Missense_Mutation	rs771137582	R679G	0.28
UCEC	chr2	111769110	3'UTR	novel		0.19
UCEC	chr2	111792537	Missense_Mutation	novel	E1513K	0.17
UCEC	chr2	111872834	Intron	novel		0.16
UCEC	chr2	111838476	Missense_Mutation	novel	P693S	0.33
UCEC	chr2	111873279	Intron	novel		0.21
UCEC	chr2	111777022	Silent	novel	E1807E	0.5
UCEC	chr2	111788282	Missense_Mutation	novel	L1584R	0.26
UCEC	chr2	111809111	Missense_Mutation	novel	S1223Y	0.39
UCEC	chr2	111856837	Missense_Mutation	novel	S470P	0.36
UCEC	chr2	111880850	Splice_Site	novel		0.37
UCEC	chr2	111873635	Missense_Mutation	novel	Q135H	0.29
UCEC	chr2	111856673	Missense_Mutation	NA	D486H	0.34
UCEC	chr2	111769211	3'UTR	novel		0.11
UCEC	chr2	111864855	Missense_Mutation	novel	A261D	0.35
UCEC	chr2	111780387	Splice_Region	novel		0.43
UCEC	chr2	111788286	Missense_Mutation	rs760585060	A1583T	0.17
UCEC	chr2	111856849	Missense_Mutation	NA	L466F	0.31
UCEC	chr2	111873330	Missense_Mutation	novel	Y169C	0.11
UCEC	chr2	111809176	Silent	novel	H1201H	0.29
UCEC	chr2	111818892	Silent	novel	S1091S	0.38
UCEC	chr2	111843572	Missense_Mutation	novel	F627S	0.41
UCEC	chr2	111778758	Missense_Mutation	NA	L1768M	0.21
UCEC	chr2	111818938	Missense_Mutation	NA	R1076Q	0.31
UCEC	chr2	111843558	Nonsense_Mutation	NA	E632*	0.48
UCEC	chr2	111788297	Missense_Mutation	NA	S1579Y	0.11
UCEC	chr2	111847779	Silent	NA	Q579Q	0.2
UCEC	chr2	111833283	Missense_Mutation	novel	H805N	0.39
UCEC	chr2	111843431	Missense_Mutation	rs772338494	R674H	0.21
UCEC	chr2	111780301	Nonsense_Mutation	novel	Q1763*	0.12
UCEC	chr2	111802490	Missense_Mutation	novel	L1387I	0.15
UCEC	chr2	111803827	Missense_Mutation	novel	L1313V	0.27
UCEC	chr2	111809103	Missense_Mutation	novel	R1226W	0.25
UCEC	chr2	111821333	Nonsense_Mutation	novel	R1038*	0.44
UCEC	chr2	111834692	Missense_Mutation	novel	L766I	0.04
UCEC	chr2	111863705	Missense_Mutation	NA	S341L	0.23
UCEC	chr2	111872664	Missense_Mutation	rs368190060	A193T	0.33
UCEC	chr2	111873216	Intron	novel		0.46
UCEC	chr2	111873354	Missense_Mutation	novel	M161T	0.47
UCEC	chr2	111873278	Intron	novel		0.12
UCEC	chr2	111788253	Missense_Mutation	novel	A1594T	0.3
UCEC	chr2	111863786	Missense_Mutation	rs375588038	P314L	0.36
UCEC	chr2	111784391	Missense_Mutation	rs776199700	W1643R	0.11
UCEC	chr2	111800861	Missense_Mutation	novel	R1411Q	0.5
UCEC	chr2	111825788	Missense_Mutation	novel	R898K	0.37
UCEC	chr2	111847856	Silent	novel	L554L	0.32
UCEC	chr2	111872847	Intron	novel		0.21
UCEC	chr2	111873278	Intron	rs754995399		0.37
UCEC	chr2	111792362	Missense_Mutation	novel	R1571M	0.38
UCEC	chr2	111792455	Missense_Mutation	novel	R1540H	0.34
UCEC	chr2	111803735	Missense_Mutation	novel	E1343D	0.32
UCEC	chr2	111834811	Missense_Mutation	novel	R726I	0.31
UCS	chr2	111863738	Missense_Mutation	rs748283556	R330H	0.35

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	DEL	0.1778	0.15279
PAAD	DEL	0.038	0.2014

Survival Analysis

Cancer	P-value	Q-value
THYM	0.048	Kaplan-Meier Survival Analysis
KIRC	0.0041	Kaplan-Meier Survival Analysis
MESO	0.00012	Kaplan-Meier Survival Analysis
ACC	0.0036	Kaplan-Meier Survival Analysis
KIRP	0.0034	Kaplan-Meier Survival Analysis
CESC	0.041	Kaplan-Meier Survival Analysis
READ	0.0085	Kaplan-Meier Survival Analysis
KICH	0.0096	Kaplan-Meier Survival Analysis
UCEC	0.00014	Kaplan-Meier Survival Analysis
LIHC	0.00046	Kaplan-Meier Survival Analysis
LGG	0.0024	Kaplan-Meier Survival Analysis
THCA	0.024	Kaplan-Meier Survival Analysis
LUAD	0.017	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000153107 (Gene tree)
Gene ID: 64682
Gene Symbol: ANAPC1
Alias: MCPR|TSG24|APC1
Full Name: anaphase promoting complex subunit 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 273,052 bases
Position: chr2:111,611,639-111,884,690
Accession: 19988
RBP type: non-canonical RBP
Summary: This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 2011]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000485325	ANAPC1-208	2369	-	-	- (aa)	-	-
ENST00000628342	ANAPC1-210	450	-	ENSP00000486322	149 (aa)	-	F8WAS1
ENST00000482177	ANAPC1-207	572	-	-	- (aa)	-	-
ENST00000489177	ANAPC1-209	1809	-	-	- (aa)	-	-
ENST00000462785	ANAPC1-204	2755	-	-	- (aa)	-	-
ENST00000467878	ANAPC1-206	580	-	-	- (aa)	-	-
ENST00000464695	ANAPC1-205	553	-	-	- (aa)	-	-
ENST00000451367	ANAPC1-203	662	-	ENSP00000405375	149 (aa)	-	F8WAS1
ENST00000643447	ANAPC1-211	1536	-	ENSP00000494863	259 (aa)	-	A0A2R8YF63
ENST00000341068	ANAPC1-201	8262	XM_011511633	ENSP00000339109	1944 (aa)	XP_011509935	Q9H1A4
ENST00000427997	ANAPC1-202	5047	-	ENSP00000396695	1452 (aa)	-	H0Y564

Gene Model

Click here to download ENSG00000153107's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa04110	Cell cycle	KEGG
hsa04114	Oocyte meiosis	KEGG
hsa04120	Ubiquitin mediated proteolysis	KEGG
hsa04914	Progesterone-mediated oocyte maturation	KEGG
hsa05166	Human T-cell leukemia virus 1 infection	KEGG

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000153107	rs17040773	2	111742458	A	Bone mineral density	22504420	[NR] unit increase	0.04	EFO_0003923
ENSG00000153107	rs11122895	2	111712578	T	Allergic sensitization	23817571	[1.05-1.13]	1.09	EFO_0005298
ENSG00000153107	rs1448190	2	111618386	A	Obesity-related traits	23251661	[NR] pg/mL increase	0.03	EFO_0004810
ENSG00000153107	rs78658973	2	111726948	?	Intraocular pressure	30054594	[0.16-0.22] unit decrease	0.1925	EFO_0004695
ENSG00000153107	rs111592775	2	111625002	TCACTTAAGCCCAG	Eosinophil percentage of granulocytes	27863252	[0.019-0.036] unit increase	0.02782232	EFO_0007996
ENSG00000153107	rs4848100	2	111630955	T	Sum eosinophil basophil counts	27863252	[0.021-0.037] unit increase	0.02903506	EFO_0005090\|EFO_0004842
ENSG00000153107	rs4848100	2	111630955	T	Eosinophil percentage of white cells	27863252	[0.021-0.038] unit increase	0.02968727	EFO_0007991
ENSG00000153107	rs4848100	2	111630955	T	Eosinophil counts	27863252	[0.023-0.04] unit increase	0.03142982	EFO_0004842
ENSG00000153107	rs1044864	2	111769289	G	Intraocular pressure	29785010	[0.18-0.24] unit increase	0.21	EFO_0004695
ENSG00000153107	rs375968322	2	111792212	?	Heel bone mineral density	30048462	[0.021-0.032] unit decrease	0.0268586	EFO_0009270
ENSG00000153107	rs113773470	2	111873052	A	Heel bone mineral density	30598549	[0.021-0.03] unit decrease	0.0254119	EFO_0009270
ENSG00000153107	rs1044864	2	111769289	?	White blood cell count	30595370			EFO_0004308
ENSG00000153107	rs11683361	2	111622982	?	Red blood cell count	30595370			EFO_0004305
ENSG00000153107	rs66739581	2	111823394	?	Red blood cell count	30595370			EFO_0004305
ENSG00000153107	rs1448190	2	111618386	?	Eczema	30595370			HP_0000964
ENSG00000153107	rs72823439	2	111732751	?	Lung function (FEV1/FVC)	30595370			EFO_0004713
ENSG00000153107	rs4848100	2	111630955	?	Eosinophil counts	30595370			EFO_0004842
ENSG00000153107	rs11683361	2	111622982	?	Mean corpuscular hemoglobin	30595370			EFO_0004527
ENSG00000153107	rs75031626	2	111834218	?	Heel bone mineral density	30595370			EFO_0009270

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000153107's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000153107	ANAPC1	100	92.387	ENSMUSG00000014355	Anapc1	100	92.387	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005680	anaphase-promoting complex	21873635.	IBA	Component
GO:0005680	anaphase-promoting complex	16364912.	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006511	ubiquitin-dependent protein catabolic process	-	TAS	Process
GO:0007091	metaphase/anaphase transition of mitotic cell cycle	21873635.	IBA	Process
GO:0031145	anaphase-promoting complex-dependent catabolic process	21873635.	IBA	Process
GO:0031145	anaphase-promoting complex-dependent catabolic process	-	TAS	Process
GO:0051301	cell division	-	IEA	Process
GO:0061630	ubiquitin protein ligase activity	21873635.	IBA	Function
GO:0070979	protein K11-linked ubiquitination	21873635.	IBA	Process
GO:0070979	protein K11-linked ubiquitination	18485873.	IDA	Process
GO:1901990	regulation of mitotic cell cycle phase transition	-	TAS	Process

EuRBPDB

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Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

GWAS

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.