EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
25531318	LARP1 post-transcriptionally regulates mTOR and contributes to cancer progression.	Oncogene	2015 Sep 24	Mura M	doi: 10.1038/onc.2014.428
26063484	MicroRNA-26a/b directly regulate La-related protein 1 and inhibit cancer cell invasion in prostate cancer.	Int J Oncol	2015 Aug	Kato M	doi: 10.3892/ijo.2015.3043
26717985	The RNA-binding protein LARP1 is a post-transcriptional regulator of survival and tumorigenesis in ovarian cancer.	Nucleic Acids Res	2016 Feb 18	Hopkins TG	doi: 10.1093/nar/gkv1515
27614686	Overexpression of LARP1 predicts poor prognosis of colorectal cancer and is expected to be a potential therapeutic target.	Tumour Biol	2016 Nov	Ye L	-
29039571	LARP1 is regulated by the XIST/miR-374a axis and functions as an oncogene in non-small cell lung carcinoma.	Oncol Rep	2017 Dec	Xu Z	doi: 10.3892/or.2017.6040
29969631	CircRNA circ-BANP-mediated miR-503/LARP1 signaling contributes to lung cancer progression.	Biochem Biophys Res Commun	2018 Sep 18	Han J	doi: 10.1016/j.bbrc.2018.06.172

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr5	154808560	Nonsense_Mutation	novel	E857*	0.37
BLCA	chr5	154802319	Missense_Mutation	novel	K600Q	0.14
BLCA	chr5	154803699	Missense_Mutation	novel	S721L	0.3
BLCA	chr5	154793922	Missense_Mutation	novel	G254S	0.14
BLCA	chr5	154793971	Missense_Mutation	rs761790075	G270V	0.07
BLCA	chr5	154800019	Missense_Mutation	novel	R488W	0.32
BLCA	chr5	154803679	Silent	novel	L714L	0.13
BLCA	chr5	154802034	Missense_Mutation	NA	L505V	0.18
BLCA	chr5	154795290	Missense_Mutation	novel	L373V	0.26
BRCA	chr5	154803601	Silent	novel	R688R	0.04
BRCA	chr5	154795256	Silent	rs148041086	I361I	0.15
BRCA	chr5	154814020	Missense_Mutation	rs148515883	P995L	0.21
BRCA	chr5	154790357	Missense_Mutation	NA	A80T	0.35
BRCA	chr5	154792789	Silent	NA	K167K	0.39
BRCA	chr5	154793829	Frame_Shift_Ins	rs769338468	*T226Hfs19**	0.46
BRCA	chr5	154799893	Missense_Mutation	novel	R446C	0.15	La
BRCA	chr5	154802197	Missense_Mutation	NA	D559V	0.31
BRCA	chr5	154790683	Silent	NA	P102P	0.13
BRCA	chr5	154792786	Missense_Mutation	NA	Q166H	0.39
BRCA	chr5	154802310	Missense_Mutation	NA	E597K	0.1
BRCA	chr5	154805925	Missense_Mutation	NA	C787F	0.26
BRCA	chr5	154790372	Missense_Mutation	rs775862354	R85C	0.1
CESC	chr5	154802097	Missense_Mutation	NA	E526Q	0.39
CESC	chr5	154793993	Silent	NA	G277G	0.42
CESC	chr5	154805945	Missense_Mutation	NA	K794Q	0.21
CESC	chr5	154816164	3'UTR	novel		0.21
CESC	chr5	154713060	Silent	NA	P45P	0.42
CESC	chr5	154793979	Missense_Mutation	rs371532945	R273C	0.32
CESC	chr5	154799666	Missense_Mutation	NA	L408F	0.25	La
CESC	chr5	154811316	Missense_Mutation	NA	F894L	0.2
CESC	chr5	154811604	Silent	rs557318389	L938L	0.48
CESC	chr5	154808557	Missense_Mutation	NA	E856Q	0.4
CESC	chr5	154814807	3'UTR	novel		0.41
COAD	chr5	154802262	Frame_Shift_Del	NA	*D583Tfs12**	0.38
COAD	chr5	154811521	Missense_Mutation	NA	Y911H	0.34
COAD	chr5	154804218	Silent	NA	K742K	0.11
COAD	chr5	154793932	Missense_Mutation	rs779604829	R257Q	0.35
COAD	chr5	154805905	Silent	NA	P780P	0.27
COAD	chr5	154811270	Missense_Mutation	NA	R879Q	0.48
COAD	chr5	154813946	Silent	novel	G970G	0.14
COAD	chr5	154756148	Intron	novel		0.35
COAD	chr5	154756185	Intron	novel		0.67
COAD	chr5	154803737	Missense_Mutation	novel	D734Y	0.08
COAD	chr5	154814122	3'UTR	rs766737574		0.6
COAD	chr5	154805902	Silent	rs138080657	T779T	0.38
COAD	chr5	154802120	Silent	rs373845474	D533D	0.06
COAD	chr5	154802006	Splice_Site	NA	X496_splice	0.13
COAD	chr5	154793918	Silent	NA	G252G	0.31
COAD	chr5	154804293	Silent	rs559936423	R767R	0.32
COAD	chr5	154811554	Missense_Mutation	NA	Y922D	0.45
COAD	chr5	154756185	Intron	novel		0.16
COAD	chr5	154811350	Missense_Mutation	NA	E906K	0.23
COAD	chr5	154802317	Missense_Mutation	novel	A599D	0.37
COAD	chr5	154805902	Silent	rs138080657	T779T	0.23
DLBC	chr5	154800025	Missense_Mutation	novel	S490P	0.82
ESCA	chr5	154802137	Missense_Mutation	novel	M539T	0.11
GBM	chr5	154803639	Missense_Mutation	novel	R701H	0.08
GBM	chr5	154793919	Frame_Shift_Ins	novel	*A253Vfs31**	0.2
GBM	chr5	154805941	Missense_Mutation	novel	L792F	0.08
GBM	chr5	154790689	Missense_Mutation	novel	E104D	0.34
GBM	chr5	154813978	Missense_Mutation	novel	S981F	0.21
GBM	chr5	154792781	Missense_Mutation	NA	G165W	0.18
GBM	chr5	154756117	Intron	NA		0.33
GBM	chr5	154803687	Frame_Shift_Ins	novel	*S718Kfs46**	0.03
GBM	chr5	154793714	Nonsense_Mutation	novel	E210*	0.18
GBM	chr5	154803617	Frame_Shift_Del	novel	*V694Sfs34**	0.22
GBM	chr5	154808550	Silent	NA	K853K	0.25
GBM	chr5	154808552	Missense_Mutation	NA	M854K	0.24
HNSC	chr5	154802042	Silent	rs17849482	S507S	0.22
HNSC	chr5	154799590	Splice_Site	novel	X383_splice	0.16
HNSC	chr5	154800001	Nonsense_Mutation	novel	E482*	0.26
HNSC	chr5	154793900	Silent	NA	S246S	0.14
HNSC	chr5	154799628	Missense_Mutation	novel	E395G	0.26
HNSC	chr5	154813957	Missense_Mutation	novel	R974M	0.42
HNSC	chr5	154793681	Missense_Mutation	novel	P199S	0.04
HNSC	chr5	154799961	Silent	novel	L468L	0.11
KIRC	chr5	154802115	Frame_Shift_Del	novel	F532*	0.35
KIRC	chr5	154804294	Missense_Mutation	NA	T768S	0.2
KIRC	chr5	154713067	Missense_Mutation	novel	E48K	0.05
KIRC	chr5	154799726	Missense_Mutation	NA	F428I	0.19	La
KIRC	chr5	154811618	Frame_Shift_Del	novel	*E945Pfs8**	0.42
KIRP	chr5	154803618	Missense_Mutation	NA	V694D	0.47
LAML	chr5	154799672	Missense_Mutation	novel	P410S	0.08	La
LAML	chr5	154799731	Silent	novel	V429V	0.08
LAML	chr5	154805912	Missense_Mutation	novel	G783C	0.46
LGG	chr5	154795242	In_Frame_Ins	novel	I361_T362insSFLPI	0.38
LIHC	chr5	154792775	Nonsense_Mutation	novel	R163*	0.1
LIHC	chr5	154794203	Missense_Mutation	NA	S314R	0.26
LUAD	chr5	154808459	Missense_Mutation	NA	E823V	0.41
LUAD	chr5	154793932	Missense_Mutation	NA	R257L	0.11
LUAD	chr5	154802251	Missense_Mutation	NA	R577L	0.27
LUAD	chr5	154792778	Missense_Mutation	novel	G164C	0.24
LUAD	chr5	154793889	Missense_Mutation	novel	D243H	0.37
LUAD	chr5	154803641	Missense_Mutation	novel	N702Y	0.38
LUAD	chr5	154806006	Missense_Mutation	novel	H814R	0.42
LUAD	chr5	154811615	Missense_Mutation	rs770314875	R942Q	0.19
LUAD	chr5	154799629	Missense_Mutation	NA	E395D	0.09
LUAD	chr5	154802396	Missense_Mutation	NA	I625M	0.05
LUAD	chr5	154799965	Missense_Mutation	NA	A470P	0.52
LUAD	chr5	154806021	Missense_Mutation	NA	R819H	0.07
LUAD	chr5	154803597	Missense_Mutation	NA	A687D	0.15
LUAD	chr5	154793635	Missense_Mutation	novel	K183N	0.08
LUAD	chr5	154803714	Missense_Mutation	novel	V726E	0.07
LUAD	chr5	154792775	Nonsense_Mutation	novel	R163*	0.36
LUAD	chr5	154795187	Missense_Mutation	novel	F338L	0.09
LUAD	chr5	154790331	Missense_Mutation	novel	S71F	0.27
LUAD	chr5	154811578	Missense_Mutation	NA	I930V	0.18
LUSC	chr5	154799732	Missense_Mutation	novel	P430S	0.19	La
LUSC	chr5	154799733	Missense_Mutation	novel	P430L	0.19	La
LUSC	chr5	154799931	Silent	novel	V458V	0.32
LUSC	chr5	154811522	Missense_Mutation	novel	Y911C	0.74
LUSC	chr5	154790339	Missense_Mutation	NA	A74T	0.09
LUSC	chr5	154811555	Missense_Mutation	novel	Y922F	0.2
OV	chr5	154800010	Missense_Mutation	novel	K485E	0.07
OV	chr5	154803717	Missense_Mutation	novel	V727G	0.06
OV	chr5	154803414	Splice_Site	NA	X668_splice	0.92
OV	chr5	154805964	Missense_Mutation	novel	H800P	0.05
OV	chr5	154802154	Frame_Shift_Ins	novel	*T545Ifs7**	0.05
OV	chr5	154799690	Nonsense_Mutation	novel	Q416*	0.07	La
OV	chr5	154792775	Frame_Shift_Ins	NA	*R163Qfs23**	0.29
OV	chr5	154799683	Silent	novel	D413D	0.08
PAAD	chr5	154792650	Missense_Mutation	novel	R121H	0.18
PAAD	chr5	154795238	Silent	novel	A355A	0.24
PAAD	chr5	154799991	Silent	rs777553186	E478E	0.2
PCPG	chr5	154804268	Missense_Mutation	novel	M759K	0.12
PRAD	chr5	154793641	Missense_Mutation	novel	E185D	0.43
PRAD	chr5	154795288	Missense_Mutation	rs755236202	A372V	0.45
PRAD	chr5	154811336	Missense_Mutation	rs758595303	T901M	0.43
READ	chr5	154793830	Frame_Shift_Del	rs779529864	*T226Pfs23**	0.38
READ	chr5	154814102	3'UTR	novel		0.24
READ	chr5	154802254	Missense_Mutation	novel	R578Q	0.2
READ	chr5	154811295	Missense_Mutation	novel	K887N	0.05
READ	chr5	154792753	Silent	novel	K155K	0.38
READ	chr5	154793596	Frame_Shift_Del	novel	*N171Tfs10**	0.3
READ	chr5	154793883	Missense_Mutation	NA	D241N	0.4
READ	chr5	154799599	Missense_Mutation	novel	K385N	0.09
READ	chr5	154799991	Missense_Mutation	novel	E478D	0.32
READ	chr5	154804200	Splice_Site	novel	X737_splice	0.44
READ	chr5	154803744	Missense_Mutation	novel	K736R	0.36
READ	chr5	154793711	Missense_Mutation	novel	G209R	0.24
SARC	chr5	154815024	3'UTR	novel		0.07
SARC	chr5	154794158	Silent	rs373569358	T299T	0.25
SARC	chr5	154804242	Silent	novel	P750P	0.22
SARC	chr5	154813947	Missense_Mutation	rs529943708	G971S	0.21
SARC	chr5	154802268	Missense_Mutation	rs765076218	D583Y	0.5
SARC	chr5	154811588	Missense_Mutation	novel	K933I	0.24
SKCM	chr5	154804241	Missense_Mutation	novel	P750L	0.17
SKCM	chr5	154712959	Missense_Mutation	NA	P12S	0.37
SKCM	chr5	154813890	Missense_Mutation	novel	P952S	0.38
SKCM	chr5	154802219	Silent	NA	I566I	0.36
SKCM	chr5	154712974	Missense_Mutation	NA	E17K	0.13
SKCM	chr5	154804238	Missense_Mutation	NA	P749L	0.28
SKCM	chr5	154811326	Nonsense_Mutation	NA	Q898*	0.4
SKCM	chr5	154794153	Missense_Mutation	rs141480802	R298C	0.81
SKCM	chr5	154803389	Missense_Mutation	NA	P660S	0.09
SKCM	chr5	154814072	Silent	rs777191209	S1012S	0.39
SKCM	chr5	154712913	5'UTR	novel		0.25
SKCM	chr5	154795260	Missense_Mutation	NA	L363F	0.27
SKCM	chr5	154793983	Missense_Mutation	novel	G274A	0.53
SKCM	chr5	154802290	Missense_Mutation	NA	S590L	0.28
SKCM	chr5	154793938	Missense_Mutation	NA	S259F	0.5
SKCM	chr5	154799636	Missense_Mutation	NA	R398C	0.23
SKCM	chr5	154793948	Silent	rs780690848	G262G	0.54
SKCM	chr5	154808463	Silent	novel	R824R	0.3
SKCM	chr5	154802267	Silent	novel	G582G	0.39
SKCM	chr5	154802268	Missense_Mutation	rs765076218	D583H	0.39
SKCM	chr5	154793943	Missense_Mutation	NA	R261C	0.07
SKCM	chr5	154712965	Missense_Mutation	novel	P14S	0.34
SKCM	chr5	154712966	Missense_Mutation	novel	P14L	0.34
STAD	chr5	154802360	Silent	NA	L613L	0.12
STAD	chr5	154803657	Missense_Mutation	rs766791311	R707H	0.24
STAD	chr5	154804252	Missense_Mutation	NA	H754Y	0.13
STAD	chr5	154802310	Missense_Mutation	NA	E597K	0.37
STAD	chr5	154803301	Missense_Mutation	NA	E630D	0.34
STAD	chr5	154804208	Missense_Mutation	NA	R739Q	0.11
STAD	chr5	154793820	Missense_Mutation	rs145378893	V220M	0.41
STAD	chr5	154802099	Silent	novel	E526E	0.23
STAD	chr5	154808583	Missense_Mutation	novel	E864D	0.32
STAD	chr5	154790372	Missense_Mutation	rs775862354	R85C	0.16
STAD	chr5	154802262	Frame_Shift_Del	NA	*D583Tfs12**	0.18
STAD	chr5	154793986	Frame_Shift_Del	novel	*G276Vfs28**	0.2
STAD	chr5	154756130	Intron	novel		0.18
STAD	chr5	154713015	Silent	NA	G30G	0.35
STAD	chr5	154756185	Intron	novel		0.56
STAD	chr5	154799904	Silent	NA	T449T	0.28
STAD	chr5	154804309	Splice_Site	NA	X772_splice	0.2
STAD	chr5	154792736	Nonsense_Mutation	NA	E150*	0.1
THCA	chr5	154811357	Splice_Site	novel	X908_splice	0.33
UCEC	chr5	154712992	Missense_Mutation	NA	A23T	0.48
UCEC	chr5	154814159	3'UTR	novel		0.28
UCEC	chr5	154795209	Missense_Mutation	NA	D346Y	0.31
UCEC	chr5	154808532	Silent	NA	R847R	0.33
UCEC	chr5	154803299	Missense_Mutation	novel	E630K	0.2
UCEC	chr5	154805917	Missense_Mutation	novel	S784R	0.39
UCEC	chr5	154793709	Missense_Mutation	rs764588090	R208H	0.13
UCEC	chr5	154793937	Missense_Mutation	NA	S259P	0.35
UCEC	chr5	154802380	Missense_Mutation	novel	P620L	0.42
UCEC	chr5	154814072	Silent	rs777191209	S1012S	0.35
UCEC	chr5	154814749	3'UTR	novel		0.23
UCEC	chr5	154813887	Frame_Shift_Del	novel	*M953Wfs13**	0.13
UCEC	chr5	154799636	Missense_Mutation	NA	R398C	0.04
UCEC	chr5	154793830	Frame_Shift_Del	rs779529864	*T226Pfs23**	0.54
UCEC	chr5	154813917	Nonsense_Mutation	novel	R961*	0.44
UCEC	chr5	154804287	Silent	rs776944280	R765R	0.46
UCEC	chr5	154804295	Missense_Mutation	novel	T768I	0.13
UCEC	chr5	154814358	3'UTR	novel		0.28
UCEC	chr5	154815188	3'UTR	novel		0.27
UCEC	chr5	154799874	Splice_Region	NA	E439E	0.28
UCEC	chr5	154790323	Splice_Site	NA	X69_splice	0.38
UCEC	chr5	154804276	Missense_Mutation	rs573986534	R762C	0.41
UCEC	chr5	154794255	Missense_Mutation	novel	R332C	0.03
UCEC	chr5	154794256	Missense_Mutation	NA	R332H	0.24
UCEC	chr5	154799880	Silent	NA	A441A	0.23
UCEC	chr5	154802171	Silent	NA	S550S	0.12
UCEC	chr5	154811336	Missense_Mutation	rs758595303	T901M	0.12
UCEC	chr5	154794256	Missense_Mutation	NA	R332H	0.49
UCEC	chr5	154803600	Missense_Mutation	rs369524030	R688H	0.41
UCEC	chr5	154816531	3'UTR	novel		0.39
UCEC	chr5	154816531	3'UTR	novel		0.48
UCEC	chr5	154790687	Nonsense_Mutation	novel	E104*	0.5
UCEC	chr5	154799918	Missense_Mutation	novel	K454R	0.12	La
UCEC	chr5	154802310	Missense_Mutation	NA	E597K	0.23
UCEC	chr5	154805948	Missense_Mutation	novel	F795V	0.1
UCEC	chr5	154802292	Missense_Mutation	rs780785993	R591C	0.27
UCEC	chr5	154794209	Silent	novel	T316T	0.29
UCEC	chr5	154802013	Nonsense_Mutation	novel	E498*	0.22
UCEC	chr5	154814471	3'UTR	novel		0.26
UCEC	chr5	154816133	3'UTR	novel		0.24
UCEC	chr5	154816367	3'UTR	novel		0.19
UCEC	chr5	154816413	3'UTR	novel		0.3
UCEC	chr5	154802251	Missense_Mutation	rs749527076	R577H	0.42
UCEC	chr5	154815310	3'UTR	rs550236847		0.42
UCEC	chr5	154802249	Missense_Mutation	NA	M576I	0.29
UCEC	chr5	154813887	Frame_Shift_Del	novel	*M953Wfs13**	0.51
UCEC	chr5	154815188	3'UTR	novel		0.37
UCEC	chr5	154814363	3'UTR	novel		0.26
UCEC	chr5	154712947	Missense_Mutation	novel	S8P	0.38
UCEC	chr5	154794127	Missense_Mutation	novel	R289Q	0.42
UCEC	chr5	154803313	Missense_Mutation	novel	K634N	0.45
UCEC	chr5	154804205	Missense_Mutation	novel	P738L	0.49
UCEC	chr5	154805999	Missense_Mutation	rs371874053	V812I	0.44
UCEC	chr5	154808468	Missense_Mutation	NA	R826H	0.46
UCEC	chr5	154808586	Silent	rs759385864	D865D	0.48
UCEC	chr5	154795279	Missense_Mutation	NA	R369L	0.38
UCEC	chr5	154793627	Missense_Mutation	novel	D181Y	0.23
UCEC	chr5	154795207	Missense_Mutation	novel	R345Q	0.46
UCEC	chr5	154816081	3'UTR	novel		0.67
UCEC	chr5	154816368	3'UTR	novel		0.38
UCEC	chr5	154817399	3'UTR	novel		0.37
UCEC	chr5	154814113	3'UTR	novel		0.3
UCEC	chr5	154793653	Silent	NA	E189E	0.39
UCEC	chr5	154795246	Missense_Mutation	novel	F358S	0.05
UCEC	chr5	154804208	Missense_Mutation	NA	R739Q	0.26
UCEC	chr5	154814072	Silent	rs777191209	S1012S	0.53
UCEC	chr5	154816299	3'UTR	novel		0.12
UCEC	chr5	154817312	3'UTR	novel		0.26
UCEC	chr5	154817451	3'UTR	novel		0.36
UCEC	chr5	154712912	5'UTR	novel		0.11
UCEC	chr5	154793826	Missense_Mutation	rs766635412	V222M	0.21
UCEC	chr5	154803298	Silent	rs772260392	V629V	0.31
UCEC	chr5	154804208	Missense_Mutation	NA	R739Q	0.23
UCEC	chr5	154815163	3'UTR	novel		0.11
UCEC	chr5	154805901	Missense_Mutation	rs763112496	T779M	0.11
UCEC	chr5	154815024	3'UTR	novel		0.17
UCEC	chr5	154814238	3'UTR	novel		0.25
UCEC	chr5	154802178	Nonsense_Mutation	novel	E553*	0.47
UCEC	chr5	154817595	3'UTR	novel		0.48
UCEC	chr5	154816531	3'UTR	novel		0.6
UCEC	chr5	154814782	3'UTR	novel		0.44
UCEC	chr5	154795176	Nonsense_Mutation	NA	E335*	0.24
UCEC	chr5	154799749	Missense_Mutation	NA	Q435H	0.3	La
UCEC	chr5	154814941	3'UTR	novel		0.1
UCEC	chr5	154817390	3'UTR	novel		0.13
UCEC	chr5	154713023	Missense_Mutation	NA	P33L	0.37
UCEC	chr5	154799736	Missense_Mutation	rs762483737	R431H	0.13	La
UCEC	chr5	154803561	Missense_Mutation	rs763725514	N675S	0.23
UCEC	chr5	154816192	3'UTR	novel		0.33
UCEC	chr5	154816312	3'UTR	novel		0.1
UCEC	chr5	154802262	Frame_Shift_Del	NA	*D583Tfs12**	0.43
UCEC	chr5	154793829	Frame_Shift_Ins	rs769338468	*T226Hfs19**	0.57
UCEC	chr5	154712931	Silent	novel	L2L	0.09
UCEC	chr5	154802230	Missense_Mutation	novel	T570I	0.13
UCEC	chr5	154816531	3'UTR	novel		0.32
UCEC	chr5	154793830	Frame_Shift_Del	rs779529864	*T226Pfs23**	0.53
UCEC	chr5	154814072	Silent	rs777191209	S1012S	0.43
UCEC	chr5	154793631	Missense_Mutation	NA	M182T	0.48
UCEC	chr5	154804244	Missense_Mutation	NA	L751S	0.08
UCEC	chr5	154799962	Missense_Mutation	NA	S469P	0.36
UCEC	chr5	154803292	Missense_Mutation	novel	Q627H	0.12
UCEC	chr5	154713040	Missense_Mutation	rs146034823	V39M	0.19
UCEC	chr5	154794255	Missense_Mutation	novel	R332C	0.29
UCEC	chr5	154802254	Missense_Mutation	novel	R578Q	0.32
UCEC	chr5	154802099	Missense_Mutation	novel	E526D	0.3
UCEC	chr5	154799663	Missense_Mutation	novel	P407S	0.44	La
UCEC	chr5	154790650	Silent	NA	G91G	0.3
UCEC	chr5	154814537	3'UTR	novel		0.48
UCEC	chr5	154815262	3'UTR	novel		0.35
UCEC	chr5	154713030	Frame_Shift_Ins	novel	*N37Kfs16**	0.35
UCS	chr5	154799708	Missense_Mutation	novel	L422F	0.27	La
UCS	chr5	154804281	Missense_Mutation	novel	E763D	0.33
UVM	chr5	154793676	Missense_Mutation	rs779864945	R197H	0.49

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
KIRP	AMP	0.1042	0.069756
KIRP	DEL	0.0382	0.11554
LAML	DEL	0.0838	1.2971e-07
LGG	DEL	0.0955	1.86e-07
LUSC	DEL	0.6168	0.002071
MESO	DEL	0.1494	0.20184
PRAD	AMP	0.0285	0.16448
SKCM	DEL	0.2997	2.2081e-08
THCA	DEL	0	0.23456

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0079	Kaplan-Meier Survival Analysis
STAD	0.043	Kaplan-Meier Survival Analysis
SARC	0.027	Kaplan-Meier Survival Analysis
HNSC	0.0093	Kaplan-Meier Survival Analysis
SKCM	0.0036	Kaplan-Meier Survival Analysis
BRCA	0.0085	Kaplan-Meier Survival Analysis
READ	0.03	Kaplan-Meier Survival Analysis
LAML	0.0075	Kaplan-Meier Survival Analysis
KICH	0.014	Kaplan-Meier Survival Analysis
UCEC	0.001	Kaplan-Meier Survival Analysis
LIHC	0.0084	Kaplan-Meier Survival Analysis
THCA	0.039	Kaplan-Meier Survival Analysis
LUAD	0.021	Kaplan-Meier Survival Analysis
UVM	0.00086	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000155506 (Gene tree)
Gene ID: 23367
Gene Symbol: LARP1
Alias: LARP|KIAA0731|MGC19556
Full Name: La ribonucleoprotein domain family member 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 134,945 bases
Position: chr5:154,682,663-154,817,607
Accession: 29531
RBP type: canonical RBP
Summary: (La Ribonucleoprotein Domain Family Member 1) is a Protein Coding gene. Among its related pathways are Translational Control. Gene Ontology (GO) annotations related to this gene include translation initiation factor binding. An important paralog of this gene is LARP1B.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000431072	La	PF05383.17	3.8e-21	1	1
ENSP00000430438	La	PF05383.17	3.8e-21	1	1
ENSP00000429904	La	PF05383.17	1.8e-20	1	1
ENSP00000336721	La	PF05383.17	2.8e-20	1	1
ENSP00000428589	La	PF05383.17	3e-20	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
21262214	The Bin3 RNA methyltransferase is required for repression of caudal translation in the Drosophila embryo.	Dev Biol	2011 Apr 1	Singh N	doi: 10.1016/j.ydbio.2011.01.017
24532714	Proteomic analysis of cap-dependent translation identifies LARP1 as a key regulator of 5'TOP mRNA translation.	Genes Dev	2014 Feb 15	Tcherkezian J	doi: 10.1101/gad.231407.113.
18515547	C. elegans La-related protein, LARP-1, localizes to germline P bodies and attenuates Ras-MAPK signaling during oogenesis.	RNA	2008 Jul	Nykamp K	doi: 10.1261/rna.1066008
20663921	LARP-1 promotes oogenesis by repressing fem-3 in the C. elegans germline.	J Cell Sci	2010 Aug 15	Zanin E	doi: 10.1242/jcs.066761
20430826	The RNA binding protein Larp1 regulates cell division, apoptosis and cell migration.	Nucleic Acids Res	2010 Sep	Burrows C	doi: 10.1093/nar/gkq294
24159927	LARP1 predict the prognosis for early-stage and AFP-normal hepatocellular carcinoma.	J Transl Med	2013 Oct 26	Xie C	doi: 10.1186/1479-5876-11-272.
26717985	The RNA-binding protein LARP1 is a post-transcriptional regulator of survival and tumorigenesis in ovarian cancer.	Nucleic Acids Res	2016 Feb 18	Hopkins TG	doi: 10.1093/nar/gkv1515
28650797	LARP1 functions as a molecular switch for mTORC1-mediated translation of an essential class of mRNAs.	Elife	2017 Jun 26	Hong S	doi: 10.7554/eLife.25237.
29039571	LARP1 is regulated by the XIST/miR-374a axis and functions as an oncogene in non-small cell lung carcinoma.	Oncol Rep	2017 Dec	Xu Z	doi: 10.3892/or.2017.6040
29722158	LARP1 on TOP of ribosome production.	Wiley Interdiscip Rev RNA	2018 May 2:e1480	Fonseca BD	doi: 10.1002/wrna.1480
25892282	The role of LARP1 in translation and beyond.	Wiley Interdiscip Rev RNA	2015 Jul-Aug	Deragon JM	doi: 10.1002/wrna.1282

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000518194	LARP1-203	450	-	ENSP00000427731	150 (aa)	-	H0YAN4
ENST00000524187	LARP1-214	287	-	-	- (aa)	-	-
ENST00000522272	LARP1-212	467	-	ENSP00000430169	36 (aa)	-	H0YBR8
ENST00000518297	LARP1-204	2630	-	ENSP00000428589	815 (aa)	-	A0A0B4J210
ENST00000518892	LARP1-208	399	-	ENSP00000429624	67 (aa)	-	H0YBJ5
ENST00000518677	LARP1-206	827	-	ENSP00000430815	183 (aa)	-	H0YC33
ENST00000521577	LARP1-211	817	-	ENSP00000428251	61 (aa)	-	H0YAX9
ENST00000519931	LARP1-210	569	-	ENSP00000429710	92 (aa)	-	E5RHK4
ENST00000524248	LARP1-215	2128	-	ENSP00000429904	610 (aa)	-	E5RH50
ENST00000517616	LARP1-202	501	-	ENSP00000429852	167 (aa)	-	H0YBM7
ENST00000518595	LARP1-205	773	-	-	- (aa)	-	-
ENST00000523163	LARP1-213	843	-	ENSP00000430438	281 (aa)	-	H0YBW1
ENST00000518742	LARP1-207	587	-	ENSP00000431072	195 (aa)	-	H0YC73
ENST00000519194	LARP1-209	529	-	-	- (aa)	-	-
ENST00000336314	LARP1-201	6595	XM_005268404	ENSP00000336721	1019 (aa)	XP_005268461	Q6PKG0

Gene Model

Click here to download ENSG00000155506's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000155506's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000155506	LARP1	99	54.355	ENSG00000138709	LARP1B	96	59.670
ENSG00000155506	LARP1	56	33.884	ENSG00000161813	LARP4	73	39.130

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000155506	LARP1	81	81.938	ENSAPOG00000020685	larp1	85	81.735	Acanthochromis_polyacanthus
ENSG00000155506	LARP1	100	96.580	ENSAMEG00000016673	LARP1	99	96.754	Ailuropoda_melanoleuca
ENSG00000155506	LARP1	89	82.099	ENSACIG00000012994	larp1	81	74.560	Amphilophus_citrinellus
ENSG00000155506	LARP1	90	80.606	ENSAOCG00000007792	larp1	97	70.686	Amphiprion_ocellaris
ENSG00000155506	LARP1	90	80.606	ENSAPEG00000022246	larp1	86	69.133	Amphiprion_percula
ENSG00000155506	LARP1	90	81.212	ENSATEG00000013523	larp1	82	68.456	Anabas_testudineus
ENSG00000155506	LARP1	100	85.388	ENSAPLG00000007559	LARP1	100	83.501	Anas_platyrhynchos
ENSG00000155506	LARP1	99	83.486	ENSACAG00000004071	LARP1	100	79.434	Anolis_carolinensis
ENSG00000155506	LARP1	100	98.856	ENSANAG00000029949	LARP1	100	98.629	Aotus_nancymaae
ENSG00000155506	LARP1	90	81.818	ENSACLG00000015256	larp1	98	67.372	Astatotilapia_calliptera
ENSG00000155506	LARP1	90	79.394	ENSAMXG00000000859	larp1	86	70.797	Astyanax_mexicanus
ENSG00000155506	LARP1	100	96.405	ENSBTAG00000008443	LARP1	88	95.440	Bos_taurus
ENSG00000155506	LARP1	100	98.913	ENSCJAG00000004454	LARP1	100	98.629	Callithrix_jacchus
ENSG00000155506	LARP1	100	96.906	ENSCAFG00000017639	LARP1	99	97.170	Canis_familiaris
ENSG00000155506	LARP1	100	96.906	ENSCAFG00020023860	LARP1	100	97.207	Canis_lupus_dingo
ENSG00000155506	LARP1	100	95.752	ENSCHIG00000014414	LARP1	89	94.301	Capra_hircus
ENSG00000155506	LARP1	100	95.765	ENSTSYG00000013732	LARP1	99	94.106	Carlito_syrichta
ENSG00000155506	LARP1	100	94.565	ENSCAPG00000013865	LARP1	87	94.194	Cavia_aperea
ENSG00000155506	LARP1	100	96.743	ENSCPOG00000003377	LARP1	100	96.436	Cavia_porcellus
ENSG00000155506	LARP1	100	99.020	ENSCCAG00000025201	LARP1	100	98.237	Cebus_capucinus
ENSG00000155506	LARP1	100	99.020	ENSCATG00000030675	LARP1	100	98.825	Cercocebus_atys
ENSG00000155506	LARP1	100	96.906	ENSCLAG00000012755	LARP1	97	96.754	Chinchilla_lanigera
ENSG00000155506	LARP1	100	98.913	ENSCSAG00000010800	LARP1	100	95.409	Chlorocebus_sabaeus
ENSG00000155506	LARP1	100	91.304	ENSCHOG00000012716	LARP1	92	84.311	Choloepus_hoffmanni
ENSG00000155506	LARP1	89	93.210	ENSCPBG00000002173	LARP1	98	78.607	Chrysemys_picta_bellii
ENSG00000155506	LARP1	80	43.017	ENSCSAVG00000008913	-	98	44.898	Ciona_savignyi
ENSG00000155506	LARP1	100	98.856	ENSCANG00000037418	LARP1	100	98.629	Colobus_angolensis_palliatus
ENSG00000155506	LARP1	100	95.277	ENSCGRG00001016913	Larp1	89	95.188	Cricetulus_griseus_chok1gshd
ENSG00000155506	LARP1	100	92.391	ENSCGRG00000009916	Larp1	99	90.533	Cricetulus_griseus_crigri
ENSG00000155506	LARP1	90	79.394	ENSCSEG00000016431	larp1	88	67.105	Cynoglossus_semilaevis
ENSG00000155506	LARP1	90	81.818	ENSCVAG00000022687	larp1	88	65.923	Cyprinodon_variegatus
ENSG00000155506	LARP1	90	79.394	ENSDARG00000101722	larp1	92	66.105	Danio_rerio
ENSG00000155506	LARP1	100	93.679	ENSDNOG00000012073	LARP1	90	91.287	Dasypus_novemcinctus
ENSG00000155506	LARP1	100	93.478	ENSDORG00000002897	Larp1	99	92.984	Dipodomys_ordii
ENSG00000155506	LARP1	100	94.463	ENSETEG00000020251	LARP1	100	96.023	Echinops_telfairi
ENSG00000155506	LARP1	100	96.466	ENSEASG00005001070	LARP1	88	95.760	Equus_asinus_asinus
ENSG00000155506	LARP1	100	96.466	ENSECAG00000017002	LARP1	70	95.760	Equus_caballus
ENSG00000155506	LARP1	99	90.110	ENSEEUG00000001065	LARP1	100	90.343	Erinaceus_europaeus
ENSG00000155506	LARP1	90	79.268	ENSELUG00000019403	larp1	87	68.079	Esox_lucius
ENSG00000155506	LARP1	100	96.580	ENSFCAG00000000592	LARP1	100	91.398	Felis_catus
ENSG00000155506	LARP1	89	93.210	ENSFALG00000008335	LARP1	99	80.856	Ficedula_albicollis
ENSG00000155506	LARP1	100	96.900	ENSFDAG00000021125	LARP1	100	96.537	Fukomys_damarensis
ENSG00000155506	LARP1	89	74.860	ENSFHEG00000020307	larp1	92	63.930	Fundulus_heteroclitus
ENSG00000155506	LARP1	89	93.210	ENSGALG00000040109	LARP1	95	79.396	Gallus_gallus
ENSG00000155506	LARP1	89	66.667	ENSGAFG00000007322	larp1	93	61.538	Gambusia_affinis
ENSG00000155506	LARP1	100	84.018	ENSGAGG00000025113	LARP1	99	80.744	Gopherus_agassizii
ENSG00000155506	LARP1	100	100.000	ENSGGOG00000006048	LARP1	100	99.509	Gorilla_gorilla
ENSG00000155506	LARP1	90	81.818	ENSHBUG00000020762	larp1	97	68.743	Haplochromis_burtoni
ENSG00000155506	LARP1	100	95.928	ENSHGLG00000006267	LARP1	91	90.864	Heterocephalus_glaber_female
ENSG00000155506	LARP1	100	96.091	ENSHGLG00100014230	-	100	96.017	Heterocephalus_glaber_male
ENSG00000155506	LARP1	100	83.696	ENSHGLG00100003395	-	88	79.811	Heterocephalus_glaber_male
ENSG00000155506	LARP1	90	80.606	ENSHCOG00000010786	larp1	85	78.998	Hippocampus_comes
ENSG00000155506	LARP1	97	71.212	ENSIPUG00000019105	Larp1	90	66.631	Ictalurus_punctatus
ENSG00000155506	LARP1	100	94.565	ENSSTOG00000005678	LARP1	99	93.508	Ictidomys_tridecemlineatus
ENSG00000155506	LARP1	100	93.478	ENSJJAG00000016950	Larp1	93	87.475	Jaculus_jaculus
ENSG00000155506	LARP1	90	82.424	ENSKMAG00000018468	larp1	95	67.883	Kryptolebias_marmoratus
ENSG00000155506	LARP1	95	76.966	ENSLBEG00000027172	larp1	85	68.483	Labrus_bergylta
ENSG00000155506	LARP1	90	83.636	ENSLOCG00000012457	larp1	90	75.196	Lepisosteus_oculatus
ENSG00000155506	LARP1	99	95.604	ENSLAFG00000008991	LARP1	92	91.919	Loxodonta_africana
ENSG00000155506	LARP1	100	98.529	ENSMFAG00000031651	LARP1	100	98.335	Macaca_fascicularis
ENSG00000155506	LARP1	100	98.233	ENSMMUG00000009411	LARP1	100	98.233	Macaca_mulatta
ENSG00000155506	LARP1	100	98.693	ENSMNEG00000039294	LARP1	100	98.768	Macaca_nemestrina
ENSG00000155506	LARP1	100	99.183	ENSMLEG00000035142	LARP1	100	98.923	Mandrillus_leucophaeus
ENSG00000155506	LARP1	90	81.212	ENSMAMG00000021788	larp1	87	67.716	Mastacembelus_armatus
ENSG00000155506	LARP1	90	81.818	ENSMZEG00005009345	larp1	98	67.372	Maylandia_zebra
ENSG00000155506	LARP1	88	93.789	ENSMGAG00000005696	LARP1	100	80.228	Meleagris_gallopavo
ENSG00000155506	LARP1	100	95.603	ENSMAUG00000001385	Larp1	95	89.665	Mesocricetus_auratus
ENSG00000155506	LARP1	100	98.233	ENSMICG00000000837	LARP1	99	96.868	Microcebus_murinus
ENSG00000155506	LARP1	100	95.440	ENSMOCG00000008920	Larp1	89	95.397	Microtus_ochrogaster
ENSG00000155506	LARP1	85	80.000	ENSMMOG00000013364	larp1	78	56.897	Mola_mola
ENSG00000155506	LARP1	100	82.143	ENSMODG00000008663	LARP1	100	82.784	Monodelphis_domestica
ENSG00000155506	LARP1	90	80.000	ENSMALG00000017180	larp1	95	67.034	Monopterus_albus
ENSG00000155506	LARP1	100	94.788	MGP_CAROLIEiJ_G0016383	Larp1	89	94.979	Mus_caroli
ENSG00000155506	LARP1	100	94.951	ENSMUSG00000037331	Larp1	89	94.979	Mus_musculus
ENSG00000155506	LARP1	100	95.277	MGP_PahariEiJ_G0017518	Larp1	89	95.293	Mus_pahari
ENSG00000155506	LARP1	100	94.951	MGP_SPRETEiJ_G0017225	Larp1	89	95.084	Mus_spretus
ENSG00000155506	LARP1	100	96.743	ENSMPUG00000013564	LARP1	91	95.615	Mustela_putorius_furo
ENSG00000155506	LARP1	100	95.765	ENSMLUG00000002608	LARP1	99	92.857	Myotis_lucifugus
ENSG00000155506	LARP1	100	88.599	ENSNGAG00000001098	Larp1	99	90.292	Nannospalax_galili
ENSG00000155506	LARP1	90	81.818	ENSNBRG00000008963	larp1	94	66.667	Neolamprologus_brichardi
ENSG00000155506	LARP1	100	96.369	ENSNLEG00000016588	LARP1	100	96.369	Nomascus_leucogenys
ENSG00000155506	LARP1	88	96.894	ENSMEUG00000002957	LARP1	100	76.996	Notamacropus_eugenii
ENSG00000155506	LARP1	100	96.580	ENSOPRG00000013014	LARP1	100	96.226	Ochotona_princeps
ENSG00000155506	LARP1	100	95.765	ENSODEG00000010824	LARP1	100	95.702	Octodon_degus
ENSG00000155506	LARP1	90	81.818	ENSONIG00000017308	larp1	87	70.042	Oreochromis_niloticus
ENSG00000155506	LARP1	100	88.073	ENSOANG00000005096	LARP1	99	82.154	Ornithorhynchus_anatinus
ENSG00000155506	LARP1	100	96.906	ENSOCUG00000013066	LARP1	95	92.502	Oryctolagus_cuniculus
ENSG00000155506	LARP1	95	75.843	ENSORLG00000000824	larp1	96	71.306	Oryzias_latipes
ENSG00000155506	LARP1	90	80.000	ENSORLG00020022241	larp1	85	68.410	Oryzias_latipes_hni
ENSG00000155506	LARP1	90	80.000	ENSORLG00015007538	larp1	85	66.489	Oryzias_latipes_hsok
ENSG00000155506	LARP1	90	80.000	ENSOMEG00000003134	larp1	87	65.078	Oryzias_melastigma
ENSG00000155506	LARP1	100	96.906	ENSOGAG00000016750	LARP1	100	96.646	Otolemur_garnettii
ENSG00000155506	LARP1	100	93.478	ENSOARG00000009893	LARP1	99	94.019	Ovis_aries
ENSG00000155506	LARP1	100	100.000	ENSPPAG00000042993	LARP1	100	99.706	Pan_paniscus
ENSG00000155506	LARP1	100	95.652	ENSPPRG00000009780	LARP1	99	92.330	Panthera_pardus
ENSG00000155506	LARP1	100	95.652	ENSPTIG00000007013	LARP1	99	91.953	Panthera_tigris_altaica
ENSG00000155506	LARP1	100	99.672	ENSPTRG00000017447	LARP1	100	99.509	Pan_troglodytes
ENSG00000155506	LARP1	100	99.020	ENSPANG00000008080	LARP1	100	98.629	Papio_anubis
ENSG00000155506	LARP1	90	81.818	ENSPKIG00000010096	larp1	85	71.123	Paramormyrops_kingsleyae
ENSG00000155506	LARP1	90	76.364	ENSPKIG00000017153	-	86	67.040	Paramormyrops_kingsleyae
ENSG00000155506	LARP1	90	80.606	ENSPMGG00000011599	larp1	89	68.578	Periophthalmus_magnuspinnatus
ENSG00000155506	LARP1	100	91.304	ENSPEMG00000022523	Larp1	99	91.832	Peromyscus_maniculatus_bairdii
ENSG00000155506	LARP1	89	94.444	ENSPCIG00000019242	LARP1	80	88.119	Phascolarctos_cinereus
ENSG00000155506	LARP1	90	81.212	ENSPFOG00000005836	larp1	85	67.712	Poecilia_formosa
ENSG00000155506	LARP1	90	81.212	ENSPLAG00000008936	larp1	85	68.220	Poecilia_latipinna
ENSG00000155506	LARP1	90	80.606	ENSPMEG00000013656	larp1	85	68.025	Poecilia_mexicana
ENSG00000155506	LARP1	90	80.606	ENSPREG00000005726	larp1	95	67.962	Poecilia_reticulata
ENSG00000155506	LARP1	99	93.407	ENSPCAG00000006407	LARP1	100	90.252	Procavia_capensis
ENSG00000155506	LARP1	100	97.394	ENSPCOG00000016949	LARP1	100	92.243	Propithecus_coquereli
ENSG00000155506	LARP1	100	95.935	ENSPVAG00000002262	LARP1	88	95.455	Pteropus_vampyrus
ENSG00000155506	LARP1	90	81.818	ENSPNYG00000007938	larp1	98	67.271	Pundamilia_nyererei
ENSG00000155506	LARP1	90	80.606	ENSPNAG00000021427	larp1	85	72.383	Pygocentrus_nattereri
ENSG00000155506	LARP1	100	93.478	ENSRNOG00000031544	Larp1	99	92.059	Rattus_norvegicus
ENSG00000155506	LARP1	100	98.856	ENSRBIG00000038005	LARP1	100	98.531	Rhinopithecus_bieti
ENSG00000155506	LARP1	100	98.856	ENSRROG00000034073	LARP1	100	99.104	Rhinopithecus_roxellana
ENSG00000155506	LARP1	100	99.183	ENSSBOG00000019816	LARP1	100	96.964	Saimiri_boliviensis_boliviensis
ENSG00000155506	LARP1	89	96.914	ENSSHAG00000011115	LARP1	99	84.277	Sarcophilus_harrisii
ENSG00000155506	LARP1	97	67.051	ENSSFOG00015020304	larp1	94	66.802	Scleropages_formosus
ENSG00000155506	LARP1	90	81.212	ENSSFOG00015018058	-	82	71.207	Scleropages_formosus
ENSG00000155506	LARP1	90	80.000	ENSSMAG00000007468	larp1	84	67.450	Scophthalmus_maximus
ENSG00000155506	LARP1	90	80.606	ENSSDUG00000000268	larp1	95	70.513	Seriola_dumerili
ENSG00000155506	LARP1	89	80.864	ENSSLDG00000016505	larp1	95	70.513	Seriola_lalandi_dorsalis
ENSG00000155506	LARP1	78	100.000	ENSSARG00000013907	-	89	93.640	Sorex_araneus
ENSG00000155506	LARP1	89	91.975	ENSSPUG00000012179	-	87	80.348	Sphenodon_punctatus
ENSG00000155506	LARP1	90	81.212	ENSSPAG00000003910	larp1	87	67.546	Stegastes_partitus
ENSG00000155506	LARP1	100	95.935	ENSSSCG00000017069	LARP1	100	95.982	Sus_scrofa
ENSG00000155506	LARP1	99	85.714	ENSTGUG00000000704	LARP1	100	83.224	Taeniopygia_guttata
ENSG00000155506	LARP1	95	75.824	ENSTRUG00000009470	larp1	86	67.050	Takifugu_rubripes
ENSG00000155506	LARP1	99	92.308	ENSTBEG00000003381	LARP1	100	94.124	Tupaia_belangeri
ENSG00000155506	LARP1	100	96.906	ENSTTRG00000015934	LARP1	100	96.122	Tursiops_truncatus
ENSG00000155506	LARP1	100	96.743	ENSUAMG00000019334	LARP1	88	96.277	Ursus_americanus
ENSG00000155506	LARP1	100	95.652	ENSUMAG00000002934	LARP1	99	93.678	Ursus_maritimus
ENSG00000155506	LARP1	100	96.906	ENSVVUG00000004644	LARP1	100	97.207	Vulpes_vulpes
ENSG00000155506	LARP1	90	90.303	ENSXETG00000008413	larp1	90	75.630	Xenopus_tropicalis
ENSG00000155506	LARP1	89	82.099	ENSXCOG00000004022	larp1	76	74.294	Xiphophorus_couchianus
ENSG00000155506	LARP1	90	81.212	ENSXMAG00000018780	larp1	85	67.962	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000339	RNA cap binding	24532714.	IDA	Function
GO:0000340	RNA 7-methylguanosine cap binding	28379136.	IDA	Function
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0003730	mRNA 3'-UTR binding	23711370.	IDA	Function
GO:0005515	protein binding	20430826.24532714.25416956.25940091.	IPI	Function
GO:0005737	cytoplasm	20430826.24532714.	IDA	Component
GO:0005844	polysome	25940091.	IDA	Component
GO:0006413	translational initiation	20430826.24532714.	IMP	Process
GO:0008190	eukaryotic initiation factor 4E binding	20430826.	IPI	Function
GO:0008283	cell proliferation	24532714.	IMP	Process
GO:0008494	translation activator activity	24532714.	IMP	Function
GO:0010494	cytoplasmic stress granule	25940091.	IDA	Component
GO:0016020	membrane	19946888.	HDA	Component
GO:0016239	positive regulation of macroautophagy	22354037.	IMP	Process
GO:0017148	negative regulation of translation	25940091.	IMP	Process
GO:0031369	translation initiation factor binding	24532714.	IDA	Function
GO:0031929	TOR signaling	24532714.	IMP	Process
GO:0031931	TORC1 complex	24532714.25940091.	IDA	Component
GO:0038202	TORC1 signaling	25940091.	IMP	Process
GO:0042788	polysomal ribosome	28673543.	IDA	Component
GO:0043024	ribosomal small subunit binding	28673543.	IDA	Function
GO:0045070	positive regulation of viral genome replication	26735137.	IMP	Process
GO:0045296	cadherin binding	25468996.	HDA	Function
GO:0045727	positive regulation of translation	-	IEA	Process
GO:0045947	negative regulation of translational initiation	28379136.	IMP	Process
GO:0048027	mRNA 5'-UTR binding	24532714.26206669.28379136.28673543.	IDA	Function
GO:0048027	mRNA 5'-UTR binding	25940091.	IMP	Function
GO:0048255	mRNA stabilization	25940091.28673543.	IMP	Process
GO:0072752	cellular response to rapamycin	25940091.	IMP	Process
GO:1990928	response to amino acid starvation	25940091.	IMP	Process

EuRBPDB

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

PPI

Paralogs

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.