EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
17341490	PGC-1alpha/beta upregulation is associated with improved oxidative phosphorylation in cells harboring nonsense mtDNA mutations.	Hum Mol Genet	2007 Apr 15	Srivastava S	-
21269472	Genetic variation of ESR1 and its co-activator PPARGC1B is synergistic in augmenting the risk of estrogen receptor-positive breast cancer.	Breast Cancer Res	2011 Jan 26	Li Y	doi: 10.1186/bcr2817.
22777349	PGC-1β mediates adaptive chemoresistance associated with mitochondrial DNA mutations.	Oncogene	2013 May 16	Yao Z	doi: 10.1038/onc.2012.259
16704985	Associations of genetic variants in the estrogen receptor coactivators PPARGC1A, PPARGC1B and EP300 with familial breast cancer.	Carcinogenesis	2006 Nov	Wirtenberger M	-
23877360	Apoptosis induced by PGC-1β in breast cancer cells is mediated by the mTOR pathway.	Oncol Rep	2013 Oct	Wang L	doi: 10.3892/or.2013.2628
28507102	The FOXO3/PGC-1β signaling axis is essential for cancer stem cell properties of pancreatic ductal adenocarcinoma.	J Biol Chem	2017 Jun 30	Kumazoe M	doi: 10.1074/jbc.M116.772111
27557380	Genetic polymorphisms of PPAR gamma, arsenic methylation capacity and breast cancer risk in Mexican women.	Salud Publica Mex	2016 Apr	Pineda-Belmontes CP	-
29888964	Promoter methylation of PGC1A and PGC1B predicts cancer incidence in a veteran cohort.	Epigenomics	2018 Jun	Kresovich JK	doi: 10.2217/epi-2017-0141

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr5	149847520	Missense_Mutation	novel	D1012N	0.34
BLCA	chr5	149836562	Missense_Mutation	rs115650813	V703I	0.5
BLCA	chr5	149836275	Missense_Mutation	novel	P607L	0.26
BLCA	chr5	149833062	Missense_Mutation	rs539604162	R330Q	0.11
BLCA	chr5	149836814	Missense_Mutation	novel	E787K	0.43
BRCA	chr5	149836839	Missense_Mutation	NA	S795N	0.32
BRCA	chr5	149836910	Missense_Mutation	novel	D819Y	0.09
BRCA	chr5	149820554	Missense_Mutation	novel	N67T	0.33
BRCA	chr5	149832832	Missense_Mutation	NA	D253E	0.35
BRCA	chr5	149826851	Missense_Mutation	rs559196017	S144L	0.13
BRCA	chr5	149826672	Splice_Site	NA	X85_splice	0.38
BRCA	chr5	149847575	3'UTR	rs763009809		0.12
BRCA	chr5	149832704	Nonsense_Mutation	NA	R211*	0.1
BRCA	chr5	149847426	Intron	NA		0.81
BRCA	chr5	149842334	Missense_Mutation	novel	F925I	0.12	RRM_1
CESC	chr5	149836346	Nonsense_Mutation	NA	E631*	0.42
CESC	chr5	149826823	Frame_Shift_Del	NA	*S137Afs69**	0.4
CESC	chr5	149836357	Silent	NA	L634L	0.27
CESC	chr5	149732891	Intron	novel		0.07
CESC	chr5	149836775	Missense_Mutation	rs771936747	A774T	0.38
CESC	chr5	149826865	Missense_Mutation	NA	E149K	0.33
CESC	chr5	149847234	Intron	novel		0.52
CESC	chr5	149847432	Intron	novel		0.44
CESC	chr5	149833636	Silent	rs751911211	E521E	0.23
COAD	chr5	149847705	3'UTR	novel		1
COAD	chr5	149820472	Missense_Mutation	novel	P40S	0.26
COAD	chr5	149833685	Missense_Mutation	rs569909824	R538W	0.5
COAD	chr5	149833131	Missense_Mutation	novel	C353Y	0.44
COAD	chr5	149833502	Missense_Mutation	rs147757452	R477W	0.11
COAD	chr5	149833233	Missense_Mutation	rs368473285	R387H	0.26
COAD	chr5	149833161	Missense_Mutation	rs45526537	T363M	0.36
COAD	chr5	149847362	Intron	novel		0.35
COAD	chr5	149730417	Silent	NA	T25T	0.26
COAD	chr5	149833686	Missense_Mutation	novel	R538Q	0.33
COAD	chr5	149832755	Nonsense_Mutation	rs781573672	Q228*	0.64
COAD	chr5	149833233	Missense_Mutation	rs368473285	R387H	0.23
COAD	chr5	149832978	Missense_Mutation	novel	R302M	0.45
COAD	chr5	149845857	Missense_Mutation	novel	F972I	0.11
COAD	chr5	149834685	Missense_Mutation	novel	C573G	0.04
COAD	chr5	149826823	Frame_Shift_Del	NA	*S137Afs69**	0.06
COAD	chr5	149847444	Intron	NA		0.27
COAD	chr5	149845826	Silent	rs367699771	G961G	0.43
COAD	chr5	149833408	In_Frame_Ins	rs775851646	E450dup	0.23
COAD	chr5	149833499	Missense_Mutation	rs780417101	V476M	0.23
COAD	chr5	149847622	3'UTR	novel		0.83
ESCA	chr5	149826708	Silent	novel	L96L	0.06
GBM	chr5	149833012	Silent	rs747264689	P313P	0.31
GBM	chr5	149826780	Missense_Mutation	novel	D120E	0.04
GBM	chr5	149840102	Missense_Mutation	rs182592244	R894W	0.26
GBM	chr5	149830766	Splice_Site	novel	X156_splice	0.19
GBM	chr5	149836503	Missense_Mutation	rs369256348	R683H	0.17
GBM	chr5	149847447	Intron	novel		0.03
GBM	chr5	149845868	Missense_Mutation	novel	S975R	0.05
GBM	chr5	149847445	Intron	novel		0.1
GBM	chr5	149833037	Missense_Mutation	novel	Q322E	0.24
GBM	chr5	149833502	Silent	rs147757452	R477R	0.32
GBM	chr5	149845841	Silent	novel	K966K	0.11
HNSC	chr5	149826871	Missense_Mutation	novel	D151H	0.24
HNSC	chr5	149820443	Missense_Mutation	novel	S30Y	0.23
HNSC	chr5	149836400	Missense_Mutation	novel	G649R	0.16
HNSC	chr5	149845882	Missense_Mutation	NA	R980Q	0.11
HNSC	chr5	149833600	Silent	novel	L509L	0.24
HNSC	chr5	149836867	Silent	novel	F804F	0.85
KIRC	chr5	149836737	Missense_Mutation	NA	R761H	0.29
KIRP	chr5	149833652	Missense_Mutation	novel	D527N	0.3
KIRP	chr5	149833499	Missense_Mutation	rs780417101	V476M	0.32
KIRP	chr5	149832791	Missense_Mutation	novel	P240S	0.38
LAML	chr5	149833115	Missense_Mutation	novel	A348T	0.08
LAML	chr5	149846033	Intron	novel		0.14
LGG	chr5	149833388	Missense_Mutation	novel	E439Q	0.06
LIHC	chr5	149836952	Missense_Mutation	novel	D833N	0.16
LIHC	chr5	149846191	Intron	novel		0.28
LIHC	chr5	149826823	Frame_Shift_Del	NA	*S137Afs69**	0.32
LIHC	chr5	149840089	Silent	rs566927619	H889H	0.28
LIHC	chr5	149833569	Missense_Mutation	NA	P499L	0.24
LUAD	chr5	149833059	Missense_Mutation	novel	S329F	0.41
LUAD	chr5	149826729	Frame_Shift_Del	novel	*P104Lfs102**	0.21
LUAD	chr5	149836532	Missense_Mutation	NA	D693Y	0.13
LUAD	chr5	149836601	Missense_Mutation	NA	G716W	0.22
LUAD	chr5	149842368	Missense_Mutation	NA	R936T	0.19	RRM_1
LUAD	chr5	149836950	Missense_Mutation	NA	S832C	0.36
LUAD	chr5	149832838	Silent	novel	P255P	0.35
LUAD	chr5	149834694	Missense_Mutation	NA	L576M	0.07
LUAD	chr5	149836524	Missense_Mutation	NA	G690V	0.44
LUAD	chr5	149836639	Silent	novel	P728P	0.37
LUAD	chr5	149826691	Missense_Mutation	NA	A91S	0.54
LUAD	chr5	149836406	Missense_Mutation	NA	A651S	0.08
LUAD	chr5	149830871	Silent	novel	R190R	0.42
LUAD	chr5	149836503	Missense_Mutation	rs369256348	R683H	0.3
LUAD	chr5	149836727	Missense_Mutation	novel	H758N	0.12
LUAD	chr5	149847564	3'UTR	novel		0.65
LUAD	chr5	149833032	Missense_Mutation	novel	S320F	0.08
LUSC	chr5	149832912	Missense_Mutation	novel	S280F	0.31
LUSC	chr5	149847631	3'UTR	novel		0.19
LUSC	chr5	149847503	Missense_Mutation	novel	Y1006F	0.78
LUSC	chr5	149845839	Nonsense_Mutation	novel	K966*	0.11
LUSC	chr5	149833526	Nonsense_Mutation	NA	E485*	0.9
LUSC	chr5	149847329	Intron	novel		0.78
LUSC	chr5	149846036	Intron	novel		0.5
LUSC	chr5	149836505	Missense_Mutation	NA	P684S	0.38
LUSC	chr5	149842371	Missense_Mutation	novel	N937S	0.24	RRM_1
LUSC	chr5	149836300	Silent	novel	T615T	0.56
LUSC	chr5	149832821	Missense_Mutation	rs369735274	P250S	0.5
LUSC	chr5	149836585	Silent	NA	R710R	0.31
LUSC	chr5	149836646	Missense_Mutation	rs745645815	E731K	0.19
MESO	chr5	149826691	Missense_Mutation	rs763781481	A91T	0.22
OV	chr5	149832720	Missense_Mutation	novel	L216Q	0.09
OV	chr5	149845853	Silent	novel	P970P	0.32
OV	chr5	149820507	Missense_Mutation	NA	D51E	0.28
OV	chr5	149832848	Missense_Mutation	NA	P259T	0.39
OV	chr5	149826780	Silent	rs576291052	D120D	0.19
OV	chr5	149832765	Missense_Mutation	novel	G231D	0.49
OV	chr5	149847559	3'UTR	novel		0.11
OV	chr5	149830873	Missense_Mutation	NA	P191L	0.12
OV	chr5	149832755	Missense_Mutation	novel	Q228K	0.06
OV	chr5	149836304	Missense_Mutation	novel	E617K	0.06
OV	chr5	149836997	Missense_Mutation	NA	L848I	0.23
PAAD	chr5	149830833	Missense_Mutation	rs189353551	A178T	0.18
PAAD	chr5	149836503	Missense_Mutation	rs369256348	R683H	0.15
PAAD	chr5	149836771	Silent	novel	E772E	0.16
PAAD	chr5	149847622	3'UTR	novel		0.17
PRAD	chr5	149833012	Silent	novel	P313P	0.09
PRAD	chr5	149832923	Missense_Mutation	NA	M284L	0.27
PRAD	chr5	149832748	Silent	novel	C225C	0.42
PRAD	chr5	149833158	Missense_Mutation	novel	A362V	0.45
PRAD	chr5	149836502	Missense_Mutation	rs201395294	R683C	0.4
PRAD	chr5	149836711	Silent	rs764935730	S752S	0.4
READ	chr5	149820517	Missense_Mutation	NA	A55T	0.26
READ	chr5	149836437	Missense_Mutation	rs779270704	R661Q	0.43
READ	chr5	149847229	Intron	NA		0.33
READ	chr5	149847259	Intron	novel		0.52
READ	chr5	149837060	Nonsense_Mutation	NA	R869*	0.44
SARC	chr5	149833483	Missense_Mutation	novel	E470D	0.08
SARC	chr5	149837016	Nonsense_Mutation	novel	S854*	0.29
SKCM	chr5	149826813	Silent	NA	P131P	0.35
SKCM	chr5	149830869	Missense_Mutation	novel	R190G	0.48
SKCM	chr5	149836532	Missense_Mutation	NA	D693Y	0.2
SKCM	chr5	149835305	Missense_Mutation	novel	P583S	0.26
SKCM	chr5	149835306	Missense_Mutation	novel	P583L	0.28
SKCM	chr5	149845854	Missense_Mutation	NA	S971T	0.07
SKCM	chr5	149847363	Intron	novel		0.36
SKCM	chr5	149847643	3'UTR	novel		0.47
SKCM	chr5	149833681	Silent	novel	L536L	0.23
SKCM	chr5	149836454	Missense_Mutation	NA	H667Y	0.16
SKCM	chr5	149836613	Missense_Mutation	NA	E720K	0.32
SKCM	chr5	149836836	In_Frame_Ins	rs756360054	S799dup	0.85
SKCM	chr5	149836550	Nonsense_Mutation	NA	R699*	0.4
SKCM	chr5	149833334	Missense_Mutation	rs141717472	R421C	0.29
SKCM	chr5	149837041	Silent	rs765250175	H862H	0.46
SKCM	chr5	149836512	Missense_Mutation	rs746361969	S686F	0.36
SKCM	chr5	149836392	Missense_Mutation	novel	A646V	0.22
SKCM	chr5	149836505	Missense_Mutation	NA	P684S	0.53
SKCM	chr5	149845989	Intron	novel		0.47
SKCM	chr5	149836933	Silent	NA	G826G	0.32
SKCM	chr5	149826742	Missense_Mutation	rs760246140	V108M	0.47
SKCM	chr5	149833146	Missense_Mutation	NA	P358L	0.23
SKCM	chr5	149833028	Missense_Mutation	NA	P319S	0.37
SKCM	chr5	149845803	Missense_Mutation	rs201010955	A954T	0.48	RRM_1
SKCM	chr5	149833052	Missense_Mutation	NA	P327S	0.25
SKCM	chr5	149833574	Missense_Mutation	NA	E501K	0.33
SKCM	chr5	149833344	Frame_Shift_Ins	novel	*E430Tfs60**	0.22
SKCM	chr5	149836868	Missense_Mutation	rs768108478	L805F	0.69
SKCM	chr5	149836448	Silent	NA	L665L	0.13
SKCM	chr5	149832988	Silent	rs750530995	P305P	0.25
SKCM	chr5	149820481	Missense_Mutation	NA	D43N	0.4
SKCM	chr5	149832808	Silent	NA	K245K	0.26
SKCM	chr5	149845848	Missense_Mutation	rs566916898	E969K	0.58
STAD	chr5	149832695	Missense_Mutation	novel	S208P	0.29
STAD	chr5	149826823	Frame_Shift_Del	NA	*S137Afs69**	0.19
STAD	chr5	149830870	Missense_Mutation	rs768972512	R190Q	0.15
STAD	chr5	149833396	Silent	NA	E441E	0.32
STAD	chr5	149847675	3'UTR	novel		0.5
STAD	chr5	149826823	Frame_Shift_Del	NA	*S137Afs69**	0.32
STAD	chr5	149836607	Missense_Mutation	novel	H718Y	0.44
STAD	chr5	149826823	Frame_Shift_Del	NA	*S137Afs69**	0.28
STAD	chr5	149845763	Silent	NA	G940G	0.11
STAD	chr5	149845881	Missense_Mutation	rs552985903	R980W	0.39
STAD	chr5	149826823	Frame_Shift_Del	NA	*S137Afs69**	0.26
STAD	chr5	149836436	Nonsense_Mutation	novel	R661*	0.36
STAD	chr5	149833282	Silent	rs141686848	T403T	0.22
STAD	chr5	149836466	Missense_Mutation	NA	A671T	0.25
STAD	chr5	149826741	Silent	rs141027780	D107D	0.17
STAD	chr5	149832897	Missense_Mutation	novel	P275H	0.25
UCEC	chr5	149836597	Silent	rs140884079	P714P	0.45
UCEC	chr5	149847622	3'UTR	novel		0.52
UCEC	chr5	149836919	Nonsense_Mutation	NA	E822*	0.19
UCEC	chr5	149830873	Missense_Mutation	novel	P191H	0.28
UCEC	chr5	149835357	Missense_Mutation	novel	G600D	0.16
UCEC	chr5	149847475	Missense_Mutation	novel	A997T	0.05
UCEC	chr5	149847622	3'UTR	novel		0.39
UCEC	chr5	149826778	Missense_Mutation	novel	D120Y	0.46
UCEC	chr5	149835337	Silent	novel	T593T	0.34
UCEC	chr5	149836912	Silent	rs141437389	D819D	0.53
UCEC	chr5	149836734	Missense_Mutation	novel	I760T	0.21
UCEC	chr5	149830856	Missense_Mutation	NA	R185S	0.19
UCEC	chr5	149836825	Frame_Shift_Del	NA	*V791Lfs2**	0.19
UCEC	chr5	149820568	Missense_Mutation	novel	P72S	0.22
UCEC	chr5	149836457	Silent	novel	L668L	0.3
UCEC	chr5	149826784	Missense_Mutation	novel	L122I	0.18
UCEC	chr5	149732890	Intron	novel		0.2
UCEC	chr5	149833396	Missense_Mutation	novel	E441D	0.28
UCEC	chr5	149847482	Missense_Mutation	rs775766632	P999L	0.34
UCEC	chr5	149845826	Silent	rs367699771	G961G	0.16
UCEC	chr5	149836460	Nonsense_Mutation	novel	R669*	0.32
UCEC	chr5	149826693	Silent	novel	A91A	0.38
UCEC	chr5	149826742	Missense_Mutation	rs760246140	V108M	0.43
UCEC	chr5	149826823	Frame_Shift_Del	NA	*S137Afs69**	0.27
UCEC	chr5	149847617	3'UTR	novel		0.34
UCEC	chr5	149837061	Missense_Mutation	rs747302115	R869Q	0.28
UCEC	chr5	149836912	Silent	rs141437389	D819D	0.34
UCEC	chr5	149826823	Frame_Shift_Del	NA	*S137Afs69**	0.18
UCEC	chr5	149826823	Frame_Shift_Del	NA	*S137Afs69**	0.37
UCEC	chr5	149836507	Silent	novel	P684P	0.25
UCEC	chr5	149840073	Missense_Mutation	rs759740325	T884M	0.39
UCEC	chr5	149842322	Missense_Mutation	rs538570659	R921C	0.44	RRM_1
UCEC	chr5	149826823	Frame_Shift_Del	NA	*S137Afs69**	0.26
UCEC	chr5	149842354	Silent	rs45572344	C931C	0.54
UCEC	chr5	149832695	Missense_Mutation	NA	S208A	0.29
UCEC	chr5	149833357	Silent	NA	Q428Q	0.25
UCEC	chr5	149833429	Silent	novel	G452G	0.22
UCEC	chr5	149833611	Missense_Mutation	novel	P513H	0.25
UCEC	chr5	149847449	Intron	rs753777048		0.36
UCEC	chr5	149845766	Missense_Mutation	novel	E941D	0.33	RRM_1
UCEC	chr5	149836900	Silent	novel	E815E	0.13
UCEC	chr5	149820445	Frame_Shift_Del	novel	*E32Rfs174**	0.33
UCEC	chr5	149833302	Missense_Mutation	NA	R410H	0.37
UCEC	chr5	149835352	Silent	novel	L598L	0.28
UCEC	chr5	149846054	Intron	novel		0.35
UCEC	chr5	149833084	Missense_Mutation	novel	W337C	0.37
UCEC	chr5	149830839	Missense_Mutation	rs777341582	R180C	0.33
UCEC	chr5	149842264	Silent	rs548316459	G901G	0.43

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
KIRP	AMP	0.1042	0.069756
KIRP	DEL	0.0382	0.11554
LAML	DEL	0.089	1.2971e-07
LUSC	DEL	0.6208	0.002071
MESO	DEL	0.1379	0.20184
PRAD	AMP	0.0264	0.16448
SKCM	DEL	0.297	2.2081e-08
THCA	AMP	0.0361	0.075436
THCA	DEL	0	0.23456

Survival Analysis

Cancer	P-value	Q-value
THYM	0.023	Kaplan-Meier Survival Analysis
MESO	0.0025	Kaplan-Meier Survival Analysis
HNSC	0.0022	Kaplan-Meier Survival Analysis
COAD	0.015	Kaplan-Meier Survival Analysis
BLCA	0.0012	Kaplan-Meier Survival Analysis
CESC	0.019	Kaplan-Meier Survival Analysis
READ	0.0013	Kaplan-Meier Survival Analysis
KICH	0.049	Kaplan-Meier Survival Analysis
UCEC	0.0026	Kaplan-Meier Survival Analysis
LIHC	0.0018	Kaplan-Meier Survival Analysis
OV	0.032	Kaplan-Meier Survival Analysis

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000155846 (Gene tree)
Gene ID: 133522
Gene Symbol: PPARGC1B
Alias: PERC|PGC1B
Full Name: PPARG coactivator 1 beta
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 127,623 bases
Position: chr5:149,730,252-149,857,874
Accession: 30022
RBP type: canonical RBP
Summary: The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000409364	RRM_1	PF00076.22	8.3e-08	1	1
ENSP00000384403	RRM_1	PF00076.22	1.1e-07	1	1
ENSP00000353638	RRM_1	PF00076.22	1.1e-07	1	1
ENSP00000377855	RRM_1	PF00076.22	1.2e-07	1	1
ENSP00000312649	RRM_1	PF00076.22	1.2e-07	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000360453	PPARGC1B-202	3004	XM_011537555	ENSP00000353638	984 (aa)	XP_011535857	Q86YN6
ENST00000461780	PPARGC1B-206	566	-	-	- (aa)	-	-
ENST00000403750	PPARGC1B-204	3146	-	ENSP00000384403	959 (aa)	-	Q86YN6
ENST00000394320	PPARGC1B-203	4803	XM_011537553	ENSP00000377855	1017 (aa)	XP_011535855	Q86YN6
ENST00000309241	PPARGC1B-201	10568	XM_005268372	ENSP00000312649	1023 (aa)	XP_005268429	Q86YN6
ENST00000492495	PPARGC1B-207	572	-	-	- (aa)	-	-
ENST00000434684	PPARGC1B-205	2457	XM_011537556	ENSP00000409364	748 (aa)	XP_011535858	H0Y713

Gene Model

Click here to download ENSG00000155846's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa04931	Insulin resistance	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000155846	Triglycerides	2.09759943155418E-6	17903299
ENSG00000155846	Lymphocyte Count	9.243e-006	-
ENSG00000155846	Lymphocyte Count	8.544e-005	-
ENSG00000155846	Lymphocyte Count	9.463e-007	-
ENSG00000155846	Neutrophils	8.618e-005	-
ENSG00000155846	Neutrophils	1.748e-005	-
ENSG00000155846	Platelet Function Tests	1.5809800E-005	-
ENSG00000155846	Platelet Function Tests	1.8800000E-006	-
ENSG00000155846	Platelet Function Tests	3.3400000E-006	-
ENSG00000155846	Platelet Function Tests	2.3637900E-005	-
ENSG00000155846	Platelet Function Tests	1.9419200E-005	-
ENSG00000155846	Fenofibrate	3E-7	22890011
ENSG00000155846	Suntan	4E-6	19340012
ENSG00000155846	Estradiol	5E-6	23251661

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000155846	rs251464	5	149816671	C	Low tan response	29739929	[0.011-0.109] unit decrease	0.06	EFO_0004279
ENSG00000155846	rs9285640	5	149762504	G	Response to fenofibrate	22890011	[18.62-41.28] unit decrease	29.95	GO_1901557
ENSG00000155846	rs32579	5	149831285	A	Tanning	19340012	[0.07-0.15] tanning ability score decrease	0.11	EFO_0004279
ENSG00000155846	rs32576	5	149833893	G	Obesity-related traits	23251661	[NR] pg/mL increase	0.03	EFO_0004697
ENSG00000155846	rs251464	5	149816671	?	Vitiligo	27723757	NR	1.155	EFO_0004208
ENSG00000155846	rs251468	5	149814922	C	Age spots	29895819	[1.2-1.39]	1.2987013	EFO_0007850
ENSG00000155846	rs251468	5	149814922	C	Freckles	29895819	[1.33-1.56]	1.4492754	EFO_0003963
ENSG00000155846	rs251464	5	149816671	?	Nevus count or cutaneous melanoma	30429480			EFO_0004632\|EFO_0000389
ENSG00000155846	rs251464	5	149816671	?	Nevus count	30429480			EFO_0004632
ENSG00000155846	rs251466	5	149816040	?	Sunburns	30595370			EFO_0003958
ENSG00000155846	rs13174179	5	149771108	?	Lung function (FEV1/FVC)	30595370			EFO_0004713

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000155846's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000155846	PPARGC1B	50	51.908	ENSG00000109819	PPARGC1A	55	51.908

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000155846	PPARGC1B	50	56.489	ENSAPOG00000018632	ppargc1a	68	56.489	Acanthochromis_polyacanthus
ENSG00000155846	PPARGC1B	100	84.705	ENSAMEG00000005287	PPARGC1B	100	84.705	Ailuropoda_melanoleuca
ENSG00000155846	PPARGC1B	50	51.908	ENSAMEG00000010421	PPARGC1A	55	51.908	Ailuropoda_melanoleuca
ENSG00000155846	PPARGC1B	50	56.489	ENSAOCG00000006754	ppargc1a	68	56.489	Amphiprion_ocellaris
ENSG00000155846	PPARGC1B	50	56.489	ENSAPEG00000022574	ppargc1a	67	56.489	Amphiprion_percula
ENSG00000155846	PPARGC1B	99	49.521	ENSAPLG00000009977	PPARGC1B	99	48.954	Anas_platyrhynchos
ENSG00000155846	PPARGC1B	100	48.155	ENSACAG00000015737	PPARGC1B	99	47.527	Anolis_carolinensis
ENSG00000155846	PPARGC1B	52	52.672	ENSACAG00000000741	PPARGC1A	56	52.672	Anolis_carolinensis
ENSG00000155846	PPARGC1B	100	93.652	ENSANAG00000021830	PPARGC1B	100	93.750	Aotus_nancymaae
ENSG00000155846	PPARGC1B	50	51.908	ENSANAG00000035930	PPARGC1A	57	51.908	Aotus_nancymaae
ENSG00000155846	PPARGC1B	51	54.198	ENSAMXG00000002461	ppargc1a	65	54.198	Astyanax_mexicanus
ENSG00000155846	PPARGC1B	50	51.145	ENSBTAG00000017024	PPARGC1A	56	51.145	Bos_taurus
ENSG00000155846	PPARGC1B	100	82.285	ENSBTAG00000012943	PPARGC1B	100	82.478	Bos_taurus
ENSG00000155846	PPARGC1B	100	92.780	ENSCJAG00000021113	PPARGC1B	100	91.477	Callithrix_jacchus
ENSG00000155846	PPARGC1B	50	51.908	ENSCJAG00000013024	PPARGC1A	53	51.908	Callithrix_jacchus
ENSG00000155846	PPARGC1B	50	51.908	ENSCAFG00000016519	PPARGC1A	55	51.908	Canis_familiaris
ENSG00000155846	PPARGC1B	100	85.010	ENSCAFG00000018275	PPARGC1B	100	84.816	Canis_familiaris
ENSG00000155846	PPARGC1B	100	84.824	ENSCAFG00020023524	PPARGC1B	100	84.623	Canis_lupus_dingo
ENSG00000155846	PPARGC1B	100	81.801	ENSCHIG00000004409	PPARGC1B	100	81.994	Capra_hircus
ENSG00000155846	PPARGC1B	56	52.308	ENSCHIG00000015991	PPARGC1A	56	52.308	Capra_hircus
ENSG00000155846	PPARGC1B	50	51.908	ENSTSYG00000010439	PPARGC1A	55	51.908	Carlito_syrichta
ENSG00000155846	PPARGC1B	99	77.894	ENSTSYG00000034354	PPARGC1B	100	78.519	Carlito_syrichta
ENSG00000155846	PPARGC1B	99	79.607	ENSCAPG00000008859	PPARGC1B	99	79.628	Cavia_aperea
ENSG00000155846	PPARGC1B	50	51.908	ENSCPOG00000001518	PPARGC1A	55	51.908	Cavia_porcellus
ENSG00000155846	PPARGC1B	100	79.517	ENSCPOG00000001958	PPARGC1B	100	79.556	Cavia_porcellus
ENSG00000155846	PPARGC1B	100	93.848	ENSCCAG00000026909	PPARGC1B	100	93.555	Cebus_capucinus
ENSG00000155846	PPARGC1B	50	51.908	ENSCCAG00000024681	PPARGC1A	57	51.908	Cebus_capucinus
ENSG00000155846	PPARGC1B	50	51.908	ENSCATG00000032575	PPARGC1A	58	51.908	Cercocebus_atys
ENSG00000155846	PPARGC1B	100	96.240	ENSCATG00000030402	PPARGC1B	100	96.240	Cercocebus_atys
ENSG00000155846	PPARGC1B	100	79.074	ENSCLAG00000015452	PPARGC1B	100	79.267	Chinchilla_lanigera
ENSG00000155846	PPARGC1B	52	48.052	ENSCLAG00000002058	PPARGC1A	58	51.042	Chinchilla_lanigera
ENSG00000155846	PPARGC1B	98	96.092	ENSCSAG00000011792	PPARGC1B	100	96.092	Chlorocebus_sabaeus
ENSG00000155846	PPARGC1B	50	51.908	ENSCSAG00000016575	PPARGC1A	55	51.908	Chlorocebus_sabaeus
ENSG00000155846	PPARGC1B	63	88.095	ENSCHOG00000005517	-	68	88.095	Choloepus_hoffmanni
ENSG00000155846	PPARGC1B	99	50.337	ENSCPBG00000007891	PPARGC1B	99	49.529	Chrysemys_picta_bellii
ENSG00000155846	PPARGC1B	100	95.122	ENSCANG00000037487	PPARGC1B	100	95.220	Colobus_angolensis_palliatus
ENSG00000155846	PPARGC1B	50	51.908	ENSCANG00000033426	PPARGC1A	58	51.908	Colobus_angolensis_palliatus
ENSG00000155846	PPARGC1B	50	50.382	ENSCGRG00001015534	Ppargc1a	55	50.382	Cricetulus_griseus_chok1gshd
ENSG00000155846	PPARGC1B	97	77.978	ENSCGRG00001017949	Ppargc1b	96	77.978	Cricetulus_griseus_chok1gshd
ENSG00000155846	PPARGC1B	98	77.323	ENSCGRG00000008387	Ppargc1b	99	77.323	Cricetulus_griseus_crigri
ENSG00000155846	PPARGC1B	50	50.382	ENSCGRG00000000200	Ppargc1a	55	50.382	Cricetulus_griseus_crigri
ENSG00000155846	PPARGC1B	50	54.198	ENSCSEG00000006884	ppargc1a	67	54.198	Cynoglossus_semilaevis
ENSG00000155846	PPARGC1B	61	42.063	ENSDARG00000101569	ppargc1b	79	43.651	Danio_rerio
ENSG00000155846	PPARGC1B	51	54.198	ENSDARG00000067829	ppargc1a	66	54.198	Danio_rerio
ENSG00000155846	PPARGC1B	95	85.627	ENSDNOG00000005985	PPARGC1B	99	85.321	Dasypus_novemcinctus
ENSG00000155846	PPARGC1B	100	79.192	ENSDORG00000012605	Ppargc1b	100	79.394	Dipodomys_ordii
ENSG00000155846	PPARGC1B	50	51.908	ENSDORG00000016276	Ppargc1a	58	51.042	Dipodomys_ordii
ENSG00000155846	PPARGC1B	100	84.100	ENSEASG00005002826	PPARGC1B	100	83.600	Equus_asinus_asinus
ENSG00000155846	PPARGC1B	50	51.908	ENSEASG00005007984	PPARGC1A	55	51.908	Equus_asinus_asinus
ENSG00000155846	PPARGC1B	100	83.622	ENSECAG00000019769	PPARGC1B	83	83.815	Equus_caballus
ENSG00000155846	PPARGC1B	50	51.908	ENSECAG00000009164	PPARGC1A	55	51.908	Equus_caballus
ENSG00000155846	PPARGC1B	51	48.739	ENSEEUG00000009219	PPARGC1A	57	52.672	Erinaceus_europaeus
ENSG00000155846	PPARGC1B	80	74.348	ENSEEUG00000014903	PPARGC1B	86	76.087	Erinaceus_europaeus
ENSG00000155846	PPARGC1B	75	55.000	ENSELUG00000014929	ppargc1b	74	44.094	Esox_lucius
ENSG00000155846	PPARGC1B	50	49.550	ENSFCAG00000000043	PPARGC1A	63	51.908	Felis_catus
ENSG00000155846	PPARGC1B	99	47.843	ENSFALG00000008858	PPARGC1B	99	50.489	Ficedula_albicollis
ENSG00000155846	PPARGC1B	50	51.908	ENSFDAG00000005659	PPARGC1A	55	51.908	Fukomys_damarensis
ENSG00000155846	PPARGC1B	97	78.734	ENSFDAG00000008719	PPARGC1B	99	78.932	Fukomys_damarensis
ENSG00000155846	PPARGC1B	51	53.435	ENSGALG00000042851	PPARGC1A	57	53.435	Gallus_gallus
ENSG00000155846	PPARGC1B	91	74.026	ENSGAGG00000012870	PPARGC1B	98	72.840	Gopherus_agassizii
ENSG00000155846	PPARGC1B	58	49.580	ENSGAGG00000007043	PPARGC1A	55	53.435	Gopherus_agassizii
ENSG00000155846	PPARGC1B	100	98.540	ENSGGOG00000009505	PPARGC1B	100	98.596	Gorilla_gorilla
ENSG00000155846	PPARGC1B	50	51.908	ENSGGOG00000009810	PPARGC1A	56	51.908	Gorilla_gorilla
ENSG00000155846	PPARGC1B	100	80.485	ENSHGLG00000005967	PPARGC1B	100	80.874	Heterocephalus_glaber_female
ENSG00000155846	PPARGC1B	50	52.672	ENSHGLG00000007022	PPARGC1A	56	52.672	Heterocephalus_glaber_female
ENSG00000155846	PPARGC1B	50	52.672	ENSHGLG00100000133	PPARGC1A	55	52.672	Heterocephalus_glaber_male
ENSG00000155846	PPARGC1B	100	79.474	ENSHGLG00100010588	PPARGC1B	100	79.879	Heterocephalus_glaber_male
ENSG00000155846	PPARGC1B	100	83.930	ENSSTOG00000024758	PPARGC1B	100	84.511	Ictidomys_tridecemlineatus
ENSG00000155846	PPARGC1B	51	52.672	ENSSTOG00000012522	PPARGC1A	55	52.672	Ictidomys_tridecemlineatus
ENSG00000155846	PPARGC1B	100	78.613	ENSJJAG00000018633	Ppargc1b	100	78.870	Jaculus_jaculus
ENSG00000155846	PPARGC1B	99	36.266	ENSLACG00000011232	PPARGC1B	100	36.616	Latimeria_chalumnae
ENSG00000155846	PPARGC1B	52	58.015	ENSLACG00000014054	PPARGC1A	58	58.015	Latimeria_chalumnae
ENSG00000155846	PPARGC1B	69	46.667	ENSLOCG00000012195	ppargc1b	89	46.667	Lepisosteus_oculatus
ENSG00000155846	PPARGC1B	52	56.489	ENSLOCG00000012350	ppargc1a	68	56.489	Lepisosteus_oculatus
ENSG00000155846	PPARGC1B	98	81.405	ENSLAFG00000012339	PPARGC1B	99	80.601	Loxodonta_africana
ENSG00000155846	PPARGC1B	50	51.908	ENSMFAG00000000534	PPARGC1A	58	51.908	Macaca_fascicularis
ENSG00000155846	PPARGC1B	100	96.188	ENSMFAG00000042269	PPARGC1B	100	96.188	Macaca_fascicularis
ENSG00000155846	PPARGC1B	100	96.188	ENSMMUG00000004749	PPARGC1B	100	96.188	Macaca_mulatta
ENSG00000155846	PPARGC1B	50	51.908	ENSMMUG00000001844	PPARGC1A	55	51.908	Macaca_mulatta
ENSG00000155846	PPARGC1B	100	96.090	ENSMNEG00000034121	PPARGC1B	100	96.090	Macaca_nemestrina
ENSG00000155846	PPARGC1B	50	51.908	ENSMNEG00000028682	PPARGC1A	58	51.908	Macaca_nemestrina
ENSG00000155846	PPARGC1B	97	96.088	ENSMLEG00000040973	PPARGC1B	100	96.088	Mandrillus_leucophaeus
ENSG00000155846	PPARGC1B	50	51.908	ENSMLEG00000034233	PPARGC1A	58	51.908	Mandrillus_leucophaeus
ENSG00000155846	PPARGC1B	51	54.198	ENSMGAG00000012485	PPARGC1A	56	54.198	Meleagris_gallopavo
ENSG00000155846	PPARGC1B	84	70.161	ENSMGAG00000003134	PPARGC1B	81	70.866	Meleagris_gallopavo
ENSG00000155846	PPARGC1B	100	77.388	ENSMAUG00000014191	Ppargc1b	100	77.290	Mesocricetus_auratus
ENSG00000155846	PPARGC1B	50	50.370	ENSMAUG00000011811	Ppargc1a	56	50.370	Mesocricetus_auratus
ENSG00000155846	PPARGC1B	100	85.352	ENSMICG00000002702	PPARGC1B	100	85.352	Microcebus_murinus
ENSG00000155846	PPARGC1B	50	51.908	ENSMICG00000015390	PPARGC1A	59	51.908	Microcebus_murinus
ENSG00000155846	PPARGC1B	100	77.810	ENSMOCG00000014885	Ppargc1b	100	77.713	Microtus_ochrogaster
ENSG00000155846	PPARGC1B	50	51.145	ENSMOCG00000008765	Ppargc1a	55	51.145	Microtus_ochrogaster
ENSG00000155846	PPARGC1B	50	51.145	ENSMODG00000000549	PPARGC1A	55	52.083	Monodelphis_domestica
ENSG00000155846	PPARGC1B	98	58.006	ENSMODG00000009891	PPARGC1B	99	57.674	Monodelphis_domestica
ENSG00000155846	PPARGC1B	100	78.328	MGP_CAROLIEiJ_G0022323	Ppargc1b	100	78.134	Mus_caroli
ENSG00000155846	PPARGC1B	50	50.382	MGP_CAROLIEiJ_G0027213	Ppargc1a	55	51.087	Mus_caroli
ENSG00000155846	PPARGC1B	100	78.384	ENSMUSG00000033871	Ppargc1b	100	78.189	Mus_musculus
ENSG00000155846	PPARGC1B	50	50.382	ENSMUSG00000029167	Ppargc1a	55	51.087	Mus_musculus
ENSG00000155846	PPARGC1B	52	47.403	MGP_PahariEiJ_G0016995	Ppargc1a	57	51.087	Mus_pahari
ENSG00000155846	PPARGC1B	100	76.544	MGP_PahariEiJ_G0019053	Ppargc1b	100	76.641	Mus_pahari
ENSG00000155846	PPARGC1B	50	50.382	MGP_SPRETEiJ_G0028208	Ppargc1a	55	51.087	Mus_spretus
ENSG00000155846	PPARGC1B	100	78.092	MGP_SPRETEiJ_G0023235	Ppargc1b	100	77.897	Mus_spretus
ENSG00000155846	PPARGC1B	50	51.908	ENSMPUG00000016736	PPARGC1A	55	51.908	Mustela_putorius_furo
ENSG00000155846	PPARGC1B	100	84.608	ENSMPUG00000014245	PPARGC1B	100	84.608	Mustela_putorius_furo
ENSG00000155846	PPARGC1B	92	77.406	ENSMLUG00000013169	PPARGC1B	100	77.301	Myotis_lucifugus
ENSG00000155846	PPARGC1B	51	48.739	ENSMLUG00000016307	PPARGC1A	55	51.908	Myotis_lucifugus
ENSG00000155846	PPARGC1B	99	78.732	ENSNGAG00000016998	Ppargc1b	99	78.439	Nannospalax_galili
ENSG00000155846	PPARGC1B	50	51.145	ENSNGAG00000015090	Ppargc1a	55	51.145	Nannospalax_galili
ENSG00000155846	PPARGC1B	100	94.824	ENSNLEG00000010193	PPARGC1B	100	94.824	Nomascus_leucogenys
ENSG00000155846	PPARGC1B	50	51.908	ENSNLEG00000016760	PPARGC1A	57	51.908	Nomascus_leucogenys
ENSG00000155846	PPARGC1B	97	75.651	ENSOPRG00000010017	PPARGC1B	99	75.651	Ochotona_princeps
ENSG00000155846	PPARGC1B	50	51.145	ENSOPRG00000012899	PPARGC1A	55	51.145	Ochotona_princeps
ENSG00000155846	PPARGC1B	100	80.000	ENSODEG00000004901	PPARGC1B	100	80.303	Octodon_degus
ENSG00000155846	PPARGC1B	50	52.672	ENSOANG00000006680	PPARGC1A	55	52.672	Ornithorhynchus_anatinus
ENSG00000155846	PPARGC1B	99	54.618	ENSOANG00000009368	PPARGC1B	99	55.120	Ornithorhynchus_anatinus
ENSG00000155846	PPARGC1B	98	78.381	ENSOCUG00000013833	PPARGC1B	100	78.381	Oryctolagus_cuniculus
ENSG00000155846	PPARGC1B	50	51.908	ENSOCUG00000014668	PPARGC1A	55	51.908	Oryctolagus_cuniculus
ENSG00000155846	PPARGC1B	98	80.915	ENSOGAG00000015983	PPARGC1B	99	79.825	Otolemur_garnettii
ENSG00000155846	PPARGC1B	50	51.145	ENSOGAG00000014559	PPARGC1A	55	51.145	Otolemur_garnettii
ENSG00000155846	PPARGC1B	98	80.000	ENSOARG00000005658	PPARGC1B	98	80.000	Ovis_aries
ENSG00000155846	PPARGC1B	50	52.308	ENSOARG00000005581	PPARGC1A	54	52.308	Ovis_aries
ENSG00000155846	PPARGC1B	100	99.166	ENSPPAG00000035226	PPARGC1B	100	99.198	Pan_paniscus
ENSG00000155846	PPARGC1B	50	51.908	ENSPPAG00000034694	PPARGC1A	60	51.908	Pan_paniscus
ENSG00000155846	PPARGC1B	100	86.227	ENSPPRG00000004608	PPARGC1B	100	86.421	Panthera_pardus
ENSG00000155846	PPARGC1B	50	49.550	ENSPPRG00000001711	PPARGC1A	63	51.908	Panthera_pardus
ENSG00000155846	PPARGC1B	99	85.227	ENSPTIG00000007391	PPARGC1B	100	84.414	Panthera_tigris_altaica
ENSG00000155846	PPARGC1B	50	49.550	ENSPTIG00000007378	PPARGC1A	63	51.908	Panthera_tigris_altaica
ENSG00000155846	PPARGC1B	50	51.908	ENSPTRG00000015954	PPARGC1A	60	51.908	Pan_troglodytes
ENSG00000155846	PPARGC1B	100	99.316	ENSPTRG00000017403	PPARGC1B	100	99.316	Pan_troglodytes
ENSG00000155846	PPARGC1B	50	51.908	ENSPANG00000005420	PPARGC1A	57	51.908	Papio_anubis
ENSG00000155846	PPARGC1B	100	96.285	ENSPANG00000009512	PPARGC1B	100	96.285	Papio_anubis
ENSG00000155846	PPARGC1B	99	51.622	ENSPSIG00000008358	PPARGC1B	99	49.392	Pelodiscus_sinensis
ENSG00000155846	PPARGC1B	50	51.145	ENSPEMG00000010892	Ppargc1a	55	51.145	Peromyscus_maniculatus_bairdii
ENSG00000155846	PPARGC1B	100	78.850	ENSPEMG00000018822	Ppargc1b	100	78.850	Peromyscus_maniculatus_bairdii
ENSG00000155846	PPARGC1B	50	51.145	ENSPCIG00000015835	PPARGC1A	55	52.083	Phascolarctos_cinereus
ENSG00000155846	PPARGC1B	90	59.823	ENSPCIG00000020102	PPARGC1B	99	56.754	Phascolarctos_cinereus
ENSG00000155846	PPARGC1B	50	51.908	ENSPPYG00000014640	PPARGC1A	55	51.908	Pongo_abelii
ENSG00000155846	PPARGC1B	100	98.729	ENSPPYG00000015938	PPARGC1B	100	98.729	Pongo_abelii
ENSG00000155846	PPARGC1B	72	82.171	ENSPCAG00000012171	PPARGC1B	74	88.462	Procavia_capensis
ENSG00000155846	PPARGC1B	50	51.908	ENSPCAG00000016308	PPARGC1A	55	51.908	Procavia_capensis
ENSG00000155846	PPARGC1B	50	51.908	ENSPCOG00000022858	PPARGC1A	76	41.038	Propithecus_coquereli
ENSG00000155846	PPARGC1B	100	87.402	ENSPCOG00000024059	PPARGC1B	100	87.695	Propithecus_coquereli
ENSG00000155846	PPARGC1B	50	51.145	ENSPVAG00000004965	PPARGC1A	55	51.145	Pteropus_vampyrus
ENSG00000155846	PPARGC1B	100	83.934	ENSPVAG00000001308	PPARGC1B	100	84.031	Pteropus_vampyrus
ENSG00000155846	PPARGC1B	55	43.750	ENSPNAG00000023871	ppargc1b	78	43.750	Pygocentrus_nattereri
ENSG00000155846	PPARGC1B	51	54.198	ENSPNAG00000010393	ppargc1a	65	54.198	Pygocentrus_nattereri
ENSG00000155846	PPARGC1B	100	77.854	ENSRNOG00000017503	Ppargc1b	100	77.854	Rattus_norvegicus
ENSG00000155846	PPARGC1B	50	51.145	ENSRNOG00000004473	Ppargc1a	55	51.145	Rattus_norvegicus
ENSG00000155846	PPARGC1B	50	51.908	ENSRBIG00000032333	PPARGC1A	58	51.908	Rhinopithecus_bieti
ENSG00000155846	PPARGC1B	100	95.431	ENSRBIG00000036724	PPARGC1B	100	95.330	Rhinopithecus_bieti
ENSG00000155846	PPARGC1B	99	95.178	ENSRROG00000029594	PPARGC1B	99	93.606	Rhinopithecus_roxellana
ENSG00000155846	PPARGC1B	50	51.908	ENSRROG00000010419	PPARGC1A	56	51.908	Rhinopithecus_roxellana
ENSG00000155846	PPARGC1B	51	51.908	ENSSBOG00000006423	PPARGC1A	56	51.908	Saimiri_boliviensis_boliviensis
ENSG00000155846	PPARGC1B	100	92.773	ENSSBOG00000028738	PPARGC1B	100	92.871	Saimiri_boliviensis_boliviensis
ENSG00000155846	PPARGC1B	50	51.145	ENSSHAG00000010033	PPARGC1A	53	52.083	Sarcophilus_harrisii
ENSG00000155846	PPARGC1B	99	58.565	ENSSHAG00000016400	PPARGC1B	99	58.565	Sarcophilus_harrisii
ENSG00000155846	PPARGC1B	50	55.725	ENSSMAG00000011571	ppargc1a	65	55.725	Scophthalmus_maximus
ENSG00000155846	PPARGC1B	99	50.048	ENSSPUG00000019271	PPARGC1B	99	49.285	Sphenodon_punctatus
ENSG00000155846	PPARGC1B	53	53.435	ENSSPUG00000013556	PPARGC1A	56	53.435	Sphenodon_punctatus
ENSG00000155846	PPARGC1B	100	76.081	ENSSSCG00000014437	PPARGC1B	100	76.465	Sus_scrofa
ENSG00000155846	PPARGC1B	50	51.908	ENSSSCG00000029275	PPARGC1A	56	51.908	Sus_scrofa
ENSG00000155846	PPARGC1B	99	48.204	ENSTGUG00000000232	PPARGC1B	100	50.100	Taeniopygia_guttata
ENSG00000155846	PPARGC1B	51	53.435	ENSTGUG00000009487	PPARGC1A	56	53.435	Taeniopygia_guttata
ENSG00000155846	PPARGC1B	51	48.739	ENSTTRG00000005327	PPARGC1A	55	51.908	Tursiops_truncatus
ENSG00000155846	PPARGC1B	99	83.778	ENSTTRG00000008430	PPARGC1B	100	83.877	Tursiops_truncatus
ENSG00000155846	PPARGC1B	50	51.908	ENSUMAG00000003557	PPARGC1A	56	51.908	Ursus_maritimus
ENSG00000155846	PPARGC1B	99	83.299	ENSUMAG00000005361	PPARGC1B	99	82.621	Ursus_maritimus
ENSG00000155846	PPARGC1B	100	85.010	ENSVVUG00000014358	PPARGC1B	100	84.816	Vulpes_vulpes
ENSG00000155846	PPARGC1B	50	51.908	ENSVVUG00000013365	PPARGC1A	55	51.908	Vulpes_vulpes
ENSG00000155846	PPARGC1B	56	43.147	ENSXETG00000020468	ppargc1a	53	51.908	Xenopus_tropicalis
ENSG00000155846	PPARGC1B	90	45.217	ENSXETG00000012711	ppargc1b	96	45.739	Xenopus_tropicalis

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001503	ossification	-	IEA	Process
GO:0003712	transcription coregulator activity	21873635.	IBA	Function
GO:0003712	transcription coregulator activity	11854298.	IDA	Function
GO:0003723	RNA binding	11854298.	NAS	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	11854298.	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005739	mitochondrion	-	IEA	Component
GO:0006355	regulation of transcription, DNA-templated	23836911.	IDA	Process
GO:0006390	mitochondrial transcription	-	IEA	Process
GO:0007015	actin filament organization	-	IEA	Process
GO:0008134	transcription factor binding	21873635.	IBA	Function
GO:0010694	positive regulation of alkaline phosphatase activity	-	IEA	Process
GO:0016592	mediator complex	11854298.	IDA	Component
GO:0030331	estrogen receptor binding	11854298.	IDA	Function
GO:0030374	nuclear receptor transcription coactivator activity	21873635.	IBA	Function
GO:0030374	nuclear receptor transcription coactivator activity	11854298.	IDA	Function
GO:0030520	intracellular estrogen receptor signaling pathway	11854298.	IDA	Process
GO:0034614	cellular response to reactive oxygen species	-	IEA	Process
GO:0042327	positive regulation of phosphorylation	-	IEA	Process
GO:0045672	positive regulation of osteoclast differentiation	-	IEA	Process
GO:0045780	positive regulation of bone resorption	-	IEA	Process
GO:0045892	negative regulation of transcription, DNA-templated	-	IEA	Process
GO:0045944	positive regulation of transcription by RNA polymerase II	21873635.	IBA	Process
GO:0045944	positive regulation of transcription by RNA polymerase II	11854298.	IDA	Process
GO:0050682	AF-2 domain binding	11854298.	IPI	Function
GO:0051091	positive regulation of DNA-binding transcription factor activity	21873635.	IBA	Process
GO:0051384	response to glucocorticoid	-	IEA	Process
GO:0051591	response to cAMP	-	IEA	Process
GO:0060346	bone trabecula formation	-	IEA	Process
GO:0120162	positive regulation of cold-induced thermogenesis	17090215.	ISS	Process

Note: Click here to get the extension of tumor abbreviations.

Note: to get the extension of tumor abbreviations.