EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr3	138402391	3'UTR	novel		0.58
BLCA	chr3	138373058	Missense_Mutation	novel	Q59K	0.47	GTP_EFTU
BLCA	chr3	138398491	Missense_Mutation	novel	V124M	0.48	GTP_EFTU
BLCA	chr3	138402203	Silent	novel	K187K	0.1
BLCA	chr3	138402315	3'UTR	rs375439719		0.17
BRCA	chr3	138398520	Missense_Mutation	NA	L133F	0.12	GTP_EFTU
BRCA	chr3	138400578	Silent	NA	V164V	0.11
BRCA	chr3	138398520	Missense_Mutation	NA	L133F	0.08	GTP_EFTU
CESC	chr3	138402552	3'UTR	novel		0.16
CESC	chr3	138403741	3'UTR	novel		0.16
CESC	chr3	138400604	Missense_Mutation	NA	R173T	0.22
CESC	chr3	138372888	Missense_Mutation	NA	A2V	0.33
COAD	chr3	138400595	Missense_Mutation	novel	D170A	0.06
COAD	chr3	138398555	Missense_Mutation	rs541672208	A145V	0.14	GTP_EFTU
ESCA	chr3	138397329	Missense_Mutation	novel	D67N	0.25	GTP_EFTU
ESCA	chr3	138402263	Silent	novel	I207I	0.21
ESCA	chr3	138403636	3'UTR	novel		0.34
GBM	chr3	138397400	Silent	rs576537185	I90I	0.53
KIRC	chr3	138398530	Missense_Mutation	NA	T137S	0.49	GTP_EFTU
LGG	chr3	138373006	Missense_Mutation	novel	D41E	0.12
LIHC	chr3	138398567	Missense_Mutation	NA	N149S	0.21
LUAD	chr3	138404594	3'UTR	novel		0.43
LUAD	chr3	138402180	Missense_Mutation	novel	P180S	0.11
LUSC	chr3	138372931	Silent	NA	L16L	0.26
LUSC	chr3	138398548	Missense_Mutation	NA	E143Q	0.21	GTP_EFTU
OV	chr3	138398528	Missense_Mutation	NA	I136S	0.46	GTP_EFTU
READ	chr3	138402347	3'UTR	novel		0.27
READ	chr3	138398556	Silent	rs754375420	A145A	0.26
READ	chr3	138397325	Splice_Region	novel	V65V	0.22
SARC	chr3	138402913	3'UTR	novel		0.32
SKCM	chr3	138397394	Silent	novel	F88F	0.33
SKCM	chr3	138400537	Missense_Mutation	NA	P151S	0.29
SKCM	chr3	138372908	Missense_Mutation	NA	D9N	0.12
SKCM	chr3	138397388	Silent	novel	D86D	0.41
SKCM	chr3	138402312	3'UTR	novel		0.34
SKCM	chr3	138400537	Missense_Mutation	NA	P151S	0.38
SKCM	chr3	138397427	Silent	NA	S99S	0.34
SKCM	chr3	138400578	Silent	novel	V164V	0.42
STAD	chr3	138397465	Missense_Mutation	novel	R112H	0.23	GTP_EFTU
STAD	chr3	138397400	Silent	rs576537185	I90I	0.26
STAD	chr3	138402238	Missense_Mutation	novel	G199D	0.13
STAD	chr3	138397410	Missense_Mutation	rs779616242	V94I	0.1	GTP_EFTU
UCEC	chr3	138402515	3'UTR	novel		0.55
UCEC	chr3	138402423	3'UTR	novel		0.5
UCEC	chr3	138402515	3'UTR	novel		0.55
UCEC	chr3	138400600	Missense_Mutation	rs758935565	V172I	0.48
UCEC	chr3	138372888	Missense_Mutation	NA	A2V	0.32
UCEC	chr3	138402557	3'UTR	novel		0.43
UCEC	chr3	138372965	Missense_Mutation	NA	A28T	0.44
UCEC	chr3	138397356	Missense_Mutation	novel	A76T	0.33	GTP_EFTU
UCEC	chr3	138372876	5'UTR	novel		0.37
UCEC	chr3	138405132	3'UTR	novel		0.4
UCEC	chr3	138402350	3'UTR	novel		0.31
UCEC	chr3	138402183	Frame_Shift_Ins	novel	*S183Kfs36**	0.32
UCEC	chr3	138402302	3'UTR	novel		0.39
UCEC	chr3	138397409	Silent	novel	S93S	0.39
UCEC	chr3	138405450	3'UTR	novel		0.33
UCEC	chr3	138405173	3'UTR	novel		0.41
UCEC	chr3	138397400	Silent	rs576537185	I90I	0.15
UCEC	chr3	138373039	Missense_Mutation	novel	K52N	0.17
UCEC	chr3	138398506	Missense_Mutation	NA	D129N	0.42	GTP_EFTU
UCEC	chr3	138402966	3'UTR	novel		0.28
UCEC	chr3	138402515	3'UTR	novel		0.48
UCEC	chr3	138405340	3'UTR	novel		0.34
UCEC	chr3	138402928	3'UTR	novel		0.33
UCEC	chr3	138402263	Silent	novel	I207I	0.41
UCEC	chr3	138402684	3'UTR	novel		0.39
UCEC	chr3	138403630	3'UTR	novel		0.35
UCEC	chr3	138402872	3'UTR	novel		0.25
UCEC	chr3	138405311	3'UTR	novel		0.29
UCEC	chr3	138402955	3'UTR	novel		0.33
UCEC	chr3	138402705	3'UTR	novel		0.48
UCEC	chr3	138397443	Missense_Mutation	novel	R105C	0.15	GTP_EFTU
UCEC	chr3	138405237	3'UTR	rs138438100		0.36
UCEC	chr3	138373075	Splice_Region	rs373753637	D64D	0.17
UCEC	chr3	138402515	3'UTR	novel		0.34
UCEC	chr3	138398506	Missense_Mutation	NA	D129N	0.24	GTP_EFTU
UCEC	chr3	138403541	3'UTR	novel		0.24

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
KIRC	DEL	0.1345	0.11092

Survival Analysis

Cancer	P-value	Q-value
STAD	0.0019	Kaplan-Meier Survival Analysis
MESO	0.022	Kaplan-Meier Survival Analysis
SKCM	0.00027	Kaplan-Meier Survival Analysis
COAD	0.041	Kaplan-Meier Survival Analysis
UCEC	0.00021	Kaplan-Meier Survival Analysis
DLBC	0.045	Kaplan-Meier Survival Analysis
LUAD	0.00062	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000158186 (Gene tree)
Gene ID: 22808
Gene Symbol: MRAS
Alias: M-RAs|R-RAS3|RRAS3
Full Name: muscle RAS oncogene homolog
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 57,888 bases
Position: chr3:138,347,648-138,405,535
Accession: 7227
RBP type: canonical RBP
Summary: This gene encodes a member of the Ras family of small GTPases. These membrane-associated proteins function as signal transducers in multiple processes including cell growth and differentiation, and dysregulation of Ras signaling has been associated with many types of cancer. The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000289104	GTP_EFTU	PF00009.27	2.4e-06	1	1
ENSP00000389682	GTP_EFTU	PF00009.27	2.4e-06	1	1
ENSP00000418356	GTP_EFTU	PF00009.27	2.4e-06	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000614350	MRAS-210	4377	-	ENSP00000484586	132 (aa)	-	O14807
ENST00000461114	MRAS-203	973	-	-	- (aa)	-	-
ENST00000474559	MRAS-205	856	XM_024453396	ENSP00000418356	208 (aa)	XP_024309164	O14807
ENST00000621127	MRAS-211	3801	-	ENSP00000481637	132 (aa)	-	O14807
ENST00000477784	MRAS-207	394	-	-	- (aa)	-	-
ENST00000423968	MRAS-202	1803	XM_005247229	ENSP00000389682	208 (aa)	XP_005247286	O14807
ENST00000289104	MRAS-201	4538	XM_005247228	ENSP00000289104	208 (aa)	XP_005247285	O14807
ENST00000475711	MRAS-206	271	-	ENSP00000417092	23 (aa)	-	C9J601
ENST00000464896	MRAS-204	1534	-	ENSP00000419582	132 (aa)	-	O14807
ENST00000478647	MRAS-208	429	-	-	- (aa)	-	-
ENST00000494949	MRAS-209	431	-	ENSP00000417685	107 (aa)	-	C9J8Q6

Gene Model

Click here to download ENSG00000158186's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa04010	MAPK signaling pathway	KEGG
hsa04014	Ras signaling pathway	KEGG
hsa04015	Rap1 signaling pathway	KEGG
hsa04072	Phospholipase D signaling pathway	KEGG
hsa04137	Mitophagy - animal	KEGG
hsa04140	Autophagy - animal	KEGG
hsa04218	Cellular senescence	KEGG
hsa04371	Apelin signaling pathway	KEGG
hsa04625	C-type lectin receptor signaling pathway	KEGG
hsa04810	Regulation of actin cytoskeleton	KEGG
hsa05205	Proteoglycans in cancer	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000158186	Pulse Wave Analysis	2.964e-005	-
ENSG00000158186	Pulse Wave Analysis	5.639e-005	-
ENSG00000158186	Pulse Wave Analysis	4.537e-005	-
ENSG00000158186	Pulse Wave Analysis	5.09e-005	-
ENSG00000158186	Pulse Wave Analysis	5.09e-005	-
ENSG00000158186	Platelet Count	5.5930000E-005	-
ENSG00000158186	Platelet Count	6.8100000E-005	-
ENSG00000158186	Platelet Count	7.3660000E-005	-
ENSG00000158186	Electrocardiography	1E-6	24324551
ENSG00000158186	Trypanosoma cruzi	1E-6	24324551
ENSG00000158186	Body Mass Index	3E-7	25673413
ENSG00000158186	Coronary Disease	7E-13	19198612
ENSG00000158186	Amyotrophic lateral sclerosis 1	3E-6	24529757
ENSG00000158186	Coronary Disease	1E-7	24262325
ENSG00000158186	Body Mass Index	7E-6	25673413
ENSG00000158186	Coronary Disease	3E-8	21378990

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000158186	rs9818870	3	138403280	T	Coronary artery disease	24262325	[1.07-1.15]	1.11	EFO_0001645
ENSG00000158186	rs1678443	3	138378692	?	PR interval in Tripanosoma cruzi seropositivity	24324551			EFO_0004462\|EFO_0005530
ENSG00000158186	rs1199333	3	138372859	?	Amyotrophic lateral sclerosis (sporadic)	24529757			EFO_0001357
ENSG00000158186	rs9818870	3	138403280	T	Coronary heart disease	19198612	[1.11-1.19]	1.15	EFO_0001645
ENSG00000158186	rs3732837	3	138403078	A	Coronary artery disease	29212778	[0.047-0.079] unit decrease	0.063	EFO_0000378
ENSG00000158186	rs185244	3	138374047	T	Coronary artery disease	29212778	[0.057-0.09] unit increase	0.0737	EFO_0000378
ENSG00000158186	rs185244	3	138374047	T	Coronary artery disease	29212778	[0.05-0.079] unit increase	0.0644	EFO_0000378
ENSG00000158186	rs2306374	3	138401110	C	Coronary heart disease	21378990	[1.07-1.16]	1.12	EFO_0001645
ENSG00000158186	rs1720825	3	138389241	A	Body mass index in physically active individuals	28448500	[0.013-0.032] kg/m2 increase	0.0225	EFO_0008002\|EFO_0004340
ENSG00000158186	rs1720825	3	138389241	?	Body mass index (joint analysis main effects and physical activity interaction)	28448500			EFO_0008002\|EFO_0004340
ENSG00000158186	rs1308362	3	138385085	A	Body mass index	28448500	[0.02-0.04] kg/m2 increase	0.0296	EFO_0008002\|EFO_0004340
ENSG00000158186	rs1720825	3	138389241	A	Body mass index	28448500	[0.017-0.035] kg/m2 increase	0.026	EFO_0008002\|EFO_0004340
ENSG00000158186	rs1720825	3	138389241	A	Body mass index	28448500	[0.016-0.04] kg/m2 increase	0.0281	EFO_0008002\|EFO_0004340
ENSG00000158186	rs1720825	3	138389241	A	Body mass index	28448500	[0.016-0.038] kg/m2 increase	0.027	EFO_0008002\|EFO_0004340
ENSG00000158186	rs1720825	3	138389241	?	Body mass index (joint analysis main effects and physical activity interaction)	28448500			EFO_0008002\|EFO_0004340
ENSG00000158186	rs1720825	3	138389241	?	Body mass index (joint analysis main effects and physical activity interaction)	28448500			EFO_0008002\|EFO_0004340
ENSG00000158186	rs1720825	3	138389241	?	Body mass index (joint analysis main effects and physical activity interaction)	28448500			EFO_0008002\|EFO_0004340
ENSG00000158186	rs1720825	3	138389241	A	Body mass index	30108127	[NR] unit increase	0.018	EFO_0004340
ENSG00000158186	rs730158	3	138359356	?	Lung function (FVC)	30595370			EFO_0004312
ENSG00000158186	rs6782181	3	138386212	G	Blond vs. brown/black hair color	30531825	NR	1.045	EFO_0003924
ENSG00000158186	rs9872754	3	138399143	?	Waist-hip ratio	30595370			EFO_0004343
ENSG00000158186	rs9818870	3	138403280	?	Cardiovascular disease	30595370			EFO_0000319
ENSG00000158186	rs9864898	3	138392909	C	Diastolic blood pressure	27841878	unit decrease	0.19	EFO_0006336
ENSG00000158186	rs9864898	3	138392909	C	Systolic blood pressure	27841878	unit decrease	0.271	EFO_0006335

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000158186's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000158186	MRAS	100	100.000	ENSAPOG00000001356	si:ch73-116o1.2	100	87.981	Acanthochromis_polyacanthus
ENSG00000158186	MRAS	100	100.000	ENSAMEG00000006368	MRAS	100	100.000	Ailuropoda_melanoleuca
ENSG00000158186	MRAS	100	100.000	ENSACIG00000015128	si:ch73-116o1.2	100	77.885	Amphilophus_citrinellus
ENSG00000158186	MRAS	100	100.000	ENSAOCG00000017207	si:ch73-116o1.2	100	87.981	Amphiprion_ocellaris
ENSG00000158186	MRAS	100	100.000	ENSAPEG00000008940	si:ch73-116o1.2	100	87.981	Amphiprion_percula
ENSG00000158186	MRAS	100	100.000	ENSATEG00000012108	si:ch73-116o1.2	100	87.981	Anabas_testudineus
ENSG00000158186	MRAS	100	99.065	ENSAPLG00000013435	MRAS	100	97.596	Anas_platyrhynchos
ENSG00000158186	MRAS	100	98.131	ENSACAG00000003841	MRAS	100	96.635	Anolis_carolinensis
ENSG00000158186	MRAS	100	100.000	ENSANAG00000033185	MRAS	100	100.000	Aotus_nancymaae
ENSG00000158186	MRAS	100	100.000	ENSACLG00000007804	si:ch73-116o1.2	100	87.500	Astatotilapia_calliptera
ENSG00000158186	MRAS	100	89.423	ENSAMXG00000010919	mras	100	89.423	Astyanax_mexicanus
ENSG00000158186	MRAS	100	100.000	ENSAMXG00000033764	si:ch73-116o1.2	100	88.462	Astyanax_mexicanus
ENSG00000158186	MRAS	100	100.000	ENSBTAG00000001497	MRAS	100	99.519	Bos_taurus
ENSG00000158186	MRAS	100	100.000	ENSCJAG00000044294	MRAS	100	100.000	Callithrix_jacchus
ENSG00000158186	MRAS	100	100.000	ENSCAFG00000007541	MRAS	100	100.000	Canis_familiaris
ENSG00000158186	MRAS	100	100.000	ENSCAFG00020008087	MRAS	100	100.000	Canis_lupus_dingo
ENSG00000158186	MRAS	100	100.000	ENSCHIG00000025837	MRAS	100	99.519	Capra_hircus
ENSG00000158186	MRAS	100	100.000	ENSCAPG00000013338	MRAS	100	99.519	Cavia_aperea
ENSG00000158186	MRAS	100	100.000	ENSCPOG00000034906	MRAS	100	99.038	Cavia_porcellus
ENSG00000158186	MRAS	100	100.000	ENSCCAG00000035799	-	100	100.000	Cebus_capucinus
ENSG00000158186	MRAS	100	100.000	ENSCATG00000043690	MRAS	100	100.000	Cercocebus_atys
ENSG00000158186	MRAS	100	100.000	ENSCLAG00000002057	MRAS	100	99.038	Chinchilla_lanigera
ENSG00000158186	MRAS	100	100.000	ENSCSAG00000011005	MRAS	100	100.000	Chlorocebus_sabaeus
ENSG00000158186	MRAS	100	99.065	ENSCPBG00000013681	MRAS	100	98.077	Chrysemys_picta_bellii
ENSG00000158186	MRAS	100	100.000	ENSCANG00000031708	MRAS	100	100.000	Colobus_angolensis_palliatus
ENSG00000158186	MRAS	100	100.000	ENSCGRG00001019182	Mras	100	99.519	Cricetulus_griseus_chok1gshd
ENSG00000158186	MRAS	100	100.000	ENSCGRG00000005782	Mras	100	99.519	Cricetulus_griseus_crigri
ENSG00000158186	MRAS	100	100.000	ENSCSEG00000018987	si:ch73-116o1.2	100	88.462	Cynoglossus_semilaevis
ENSG00000158186	MRAS	100	100.000	ENSCVAG00000008389	si:ch73-116o1.2	100	87.981	Cyprinodon_variegatus
ENSG00000158186	MRAS	98	90.476	ENSDARG00000062865	mras	99	86.339	Danio_rerio
ENSG00000158186	MRAS	100	88.942	ENSDARG00000075285	si:ch73-116o1.2	100	88.942	Danio_rerio
ENSG00000158186	MRAS	100	100.000	ENSDORG00000025032	Mras	100	98.558	Dipodomys_ordii
ENSG00000158186	MRAS	100	100.000	ENSETEG00000016304	MRAS	100	99.038	Echinops_telfairi
ENSG00000158186	MRAS	93	86.275	ENSEBUG00000014186	-	81	87.778	Eptatretus_burgeri
ENSG00000158186	MRAS	100	100.000	ENSEASG00005003778	MRAS	100	99.519	Equus_asinus_asinus
ENSG00000158186	MRAS	100	100.000	ENSECAG00000018736	MRAS	100	99.519	Equus_caballus
ENSG00000158186	MRAS	100	100.000	ENSEEUG00000007832	MRAS	100	97.596	Erinaceus_europaeus
ENSG00000158186	MRAS	100	100.000	ENSELUG00000017558	mras	100	88.462	Esox_lucius
ENSG00000158186	MRAS	100	95.833	ENSELUG00000005090	si:ch73-116o1.2	88	88.995	Esox_lucius
ENSG00000158186	MRAS	100	100.000	ENSFCAG00000026623	MRAS	100	100.000	Felis_catus
ENSG00000158186	MRAS	100	99.065	ENSFALG00000013196	MRAS	100	98.077	Ficedula_albicollis
ENSG00000158186	MRAS	100	100.000	ENSFDAG00000019759	MRAS	100	99.519	Fukomys_damarensis
ENSG00000158186	MRAS	100	100.000	ENSFHEG00000004875	si:ch73-116o1.2	100	87.981	Fundulus_heteroclitus
ENSG00000158186	MRAS	100	100.000	ENSGMOG00000012623	si:ch73-116o1.2	100	94.286	Gadus_morhua
ENSG00000158186	MRAS	100	99.065	ENSGALG00000011592	MRAS	100	97.596	Gallus_gallus
ENSG00000158186	MRAS	100	100.000	ENSGAFG00000018295	si:ch73-116o1.2	100	87.981	Gambusia_affinis
ENSG00000158186	MRAS	100	86.538	ENSGACG00000007818	si:ch73-116o1.2	100	86.538	Gasterosteus_aculeatus
ENSG00000158186	MRAS	100	99.065	ENSGAGG00000020094	MRAS	100	97.596	Gopherus_agassizii
ENSG00000158186	MRAS	100	100.000	ENSGGOG00000011092	MRAS	100	100.000	Gorilla_gorilla
ENSG00000158186	MRAS	100	100.000	ENSHBUG00000017973	si:ch73-116o1.2	100	87.500	Haplochromis_burtoni
ENSG00000158186	MRAS	100	100.000	ENSHGLG00000014208	MRAS	100	100.000	Heterocephalus_glaber_female
ENSG00000158186	MRAS	100	100.000	ENSHGLG00100015232	MRAS	100	100.000	Heterocephalus_glaber_male
ENSG00000158186	MRAS	100	100.000	ENSHCOG00000018456	si:ch73-116o1.2	100	89.423	Hippocampus_comes
ENSG00000158186	MRAS	100	87.981	ENSIPUG00000013954	rasm	100	87.500	Ictalurus_punctatus
ENSG00000158186	MRAS	100	100.000	ENSIPUG00000000962	MRAS	100	89.423	Ictalurus_punctatus
ENSG00000158186	MRAS	100	100.000	ENSSTOG00000012534	MRAS	100	99.519	Ictidomys_tridecemlineatus
ENSG00000158186	MRAS	100	100.000	ENSJJAG00000003840	Mras	100	99.519	Jaculus_jaculus
ENSG00000158186	MRAS	100	100.000	ENSKMAG00000017893	mras	100	87.019	Kryptolebias_marmoratus
ENSG00000158186	MRAS	100	87.019	ENSLBEG00000025705	si:ch73-116o1.2	100	87.019	Labrus_bergylta
ENSG00000158186	MRAS	100	93.939	ENSLACG00000010042	-	100	93.750	Latimeria_chalumnae
ENSG00000158186	MRAS	100	67.290	ENSLACG00000016958	-	100	62.500	Latimeria_chalumnae
ENSG00000158186	MRAS	100	100.000	ENSLOCG00000001886	mras	99	93.269	Lepisosteus_oculatus
ENSG00000158186	MRAS	100	100.000	ENSLAFG00000010809	MRAS	100	98.565	Loxodonta_africana
ENSG00000158186	MRAS	100	100.000	ENSMFAG00000040143	MRAS	100	100.000	Macaca_fascicularis
ENSG00000158186	MRAS	100	100.000	ENSMMUG00000007756	MRAS	100	100.000	Macaca_mulatta
ENSG00000158186	MRAS	100	100.000	ENSMNEG00000029621	MRAS	100	100.000	Macaca_nemestrina
ENSG00000158186	MRAS	100	100.000	ENSMLEG00000034659	MRAS	100	100.000	Mandrillus_leucophaeus
ENSG00000158186	MRAS	100	100.000	ENSMAMG00000013700	si:ch73-116o1.2	100	87.981	Mastacembelus_armatus
ENSG00000158186	MRAS	100	100.000	ENSMZEG00005001534	si:ch73-116o1.2	100	87.500	Maylandia_zebra
ENSG00000158186	MRAS	100	99.065	ENSMGAG00000011812	MRAS	100	97.596	Meleagris_gallopavo
ENSG00000158186	MRAS	100	100.000	ENSMAUG00000010837	Mras	100	99.519	Mesocricetus_auratus
ENSG00000158186	MRAS	100	100.000	ENSMICG00000049226	MRAS	100	99.038	Microcebus_murinus
ENSG00000158186	MRAS	100	100.000	ENSMOCG00000000582	Mras	100	100.000	Microtus_ochrogaster
ENSG00000158186	MRAS	100	100.000	ENSMODG00000018565	MRAS	100	98.558	Monodelphis_domestica
ENSG00000158186	MRAS	100	100.000	ENSMALG00000012930	si:ch73-116o1.2	100	87.500	Monopterus_albus
ENSG00000158186	MRAS	100	96.635	MGP_CAROLIEiJ_G0032562	Mras	100	96.635	Mus_caroli
ENSG00000158186	MRAS	100	96.635	ENSMUSG00000032470	Mras	100	96.635	Mus_musculus
ENSG00000158186	MRAS	100	97.115	MGP_PahariEiJ_G0015431	Mras	100	97.115	Mus_pahari
ENSG00000158186	MRAS	100	97.115	MGP_SPRETEiJ_G0033706	Mras	100	97.115	Mus_spretus
ENSG00000158186	MRAS	100	100.000	ENSMPUG00000009182	MRAS	100	99.519	Mustela_putorius_furo
ENSG00000158186	MRAS	100	99.242	ENSMLUG00000007927	MRAS	100	99.306	Myotis_lucifugus
ENSG00000158186	MRAS	100	100.000	ENSNGAG00000013556	Mras	100	99.519	Nannospalax_galili
ENSG00000158186	MRAS	100	100.000	ENSNBRG00000014613	si:ch73-116o1.2	100	87.500	Neolamprologus_brichardi
ENSG00000158186	MRAS	100	100.000	ENSNLEG00000004197	MRAS	100	99.519	Nomascus_leucogenys
ENSG00000158186	MRAS	100	99.065	ENSMEUG00000003081	-	100	81.095	Notamacropus_eugenii
ENSG00000158186	MRAS	100	100.000	ENSODEG00000018151	MRAS	100	100.000	Octodon_degus
ENSG00000158186	MRAS	100	100.000	ENSONIG00000004448	si:ch73-116o1.2	100	85.849	Oreochromis_niloticus
ENSG00000158186	MRAS	100	98.131	ENSOANG00000007543	MRAS	100	95.139	Ornithorhynchus_anatinus
ENSG00000158186	MRAS	100	100.000	ENSOCUG00000005929	MRAS	100	100.000	Oryctolagus_cuniculus
ENSG00000158186	MRAS	100	87.560	ENSORLG00000018119	si:ch73-116o1.2	100	87.081	Oryzias_latipes
ENSG00000158186	MRAS	100	87.981	ENSORLG00020012306	si:ch73-116o1.2	100	87.981	Oryzias_latipes_hni
ENSG00000158186	MRAS	100	88.462	ENSORLG00015008252	si:ch73-116o1.2	100	88.462	Oryzias_latipes_hsok
ENSG00000158186	MRAS	100	100.000	ENSOGAG00000004034	MRAS	100	98.565	Otolemur_garnettii
ENSG00000158186	MRAS	100	100.000	ENSOARG00000007444	MRAS	100	99.043	Ovis_aries
ENSG00000158186	MRAS	100	100.000	ENSPPAG00000036377	MRAS	100	100.000	Pan_paniscus
ENSG00000158186	MRAS	100	100.000	ENSPPRG00000005624	MRAS	100	100.000	Panthera_pardus
ENSG00000158186	MRAS	100	100.000	ENSPTIG00000019813	MRAS	100	100.000	Panthera_tigris_altaica
ENSG00000158186	MRAS	100	100.000	ENSPTRG00000015445	MRAS	100	100.000	Pan_troglodytes
ENSG00000158186	MRAS	100	100.000	ENSPANG00000007201	MRAS	100	100.000	Papio_anubis
ENSG00000158186	MRAS	100	100.000	ENSPKIG00000019227	-	73	93.182	Paramormyrops_kingsleyae
ENSG00000158186	MRAS	100	99.065	ENSPSIG00000009592	MRAS	100	98.077	Pelodiscus_sinensis
ENSG00000158186	MRAS	100	100.000	ENSPCIG00000006467	MRAS	100	99.038	Phascolarctos_cinereus
ENSG00000158186	MRAS	100	100.000	ENSPFOG00000000601	si:ch73-116o1.2	100	87.981	Poecilia_formosa
ENSG00000158186	MRAS	100	100.000	ENSPLAG00000011855	si:ch73-116o1.2	100	87.981	Poecilia_latipinna
ENSG00000158186	MRAS	100	100.000	ENSPMEG00000012042	si:ch73-116o1.2	100	87.981	Poecilia_mexicana
ENSG00000158186	MRAS	100	100.000	ENSPREG00000016102	si:ch73-116o1.2	100	87.500	Poecilia_reticulata
ENSG00000158186	MRAS	100	100.000	ENSPPYG00000014142	MRAS	100	100.000	Pongo_abelii
ENSG00000158186	MRAS	100	100.000	ENSPCOG00000023517	MRAS	100	99.038	Propithecus_coquereli
ENSG00000158186	MRAS	100	100.000	ENSPNYG00000005416	si:ch73-116o1.2	100	87.500	Pundamilia_nyererei
ENSG00000158186	MRAS	100	88.942	ENSPNAG00000013747	mras	100	88.942	Pygocentrus_nattereri
ENSG00000158186	MRAS	100	100.000	ENSPNAG00000026295	si:ch73-116o1.2	100	89.423	Pygocentrus_nattereri
ENSG00000158186	MRAS	100	100.000	ENSRNOG00000014060	Mras	100	97.596	Rattus_norvegicus
ENSG00000158186	MRAS	100	100.000	ENSRBIG00000038196	MRAS	100	100.000	Rhinopithecus_bieti
ENSG00000158186	MRAS	100	100.000	ENSRROG00000029485	MRAS	100	100.000	Rhinopithecus_roxellana
ENSG00000158186	MRAS	100	100.000	ENSSBOG00000023115	MRAS	100	99.519	Saimiri_boliviensis_boliviensis
ENSG00000158186	MRAS	100	100.000	ENSSHAG00000009032	MRAS	100	98.558	Sarcophilus_harrisii
ENSG00000158186	MRAS	100	100.000	ENSSFOG00015020319	mras	100	90.909	Scleropages_formosus
ENSG00000158186	MRAS	100	87.981	ENSSMAG00000004806	si:ch73-116o1.2	100	87.981	Scophthalmus_maximus
ENSG00000158186	MRAS	100	100.000	ENSSDUG00000010675	si:ch73-116o1.2	92	89.000	Seriola_dumerili
ENSG00000158186	MRAS	100	100.000	ENSSLDG00000021833	si:ch73-116o1.2	100	87.500	Seriola_lalandi_dorsalis
ENSG00000158186	MRAS	100	98.131	ENSSPUG00000017750	MRAS	100	96.154	Sphenodon_punctatus
ENSG00000158186	MRAS	100	100.000	ENSSSCG00000027443	MRAS	100	99.519	Sus_scrofa
ENSG00000158186	MRAS	100	99.065	ENSTGUG00000004727	MRAS	100	98.077	Taeniopygia_guttata
ENSG00000158186	MRAS	100	100.000	ENSTRUG00000005805	mras	100	87.019	Takifugu_rubripes
ENSG00000158186	MRAS	100	100.000	ENSTNIG00000007566	si:ch73-116o1.2	100	87.019	Tetraodon_nigroviridis
ENSG00000158186	MRAS	100	100.000	ENSTTRG00000006194	MRAS	100	98.857	Tursiops_truncatus
ENSG00000158186	MRAS	100	100.000	ENSUAMG00000008388	MRAS	100	100.000	Ursus_americanus
ENSG00000158186	MRAS	100	100.000	ENSUMAG00000014965	MRAS	86	99.515	Ursus_maritimus
ENSG00000158186	MRAS	100	100.000	ENSVVUG00000026571	-	100	100.000	Vulpes_vulpes
ENSG00000158186	MRAS	100	93.458	ENSXETG00000005505	MRAS	100	92.308	Xenopus_tropicalis
ENSG00000158186	MRAS	100	100.000	ENSXMAG00000001962	si:ch73-116o1.2	100	87.981	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003924	GTPase activity	-	IEA	Function
GO:0005515	protein binding	25137548.	IPI	Function
GO:0005525	GTP binding	-	IEA	Function
GO:0005886	plasma membrane	-	IEA	Component
GO:0007265	Ras protein signal transduction	10446149.	TAS	Process
GO:0007275	multicellular organism development	10446149.	TAS	Process
GO:0007517	muscle organ development	9395237.	TAS	Process
GO:0030036	actin cytoskeleton organization	9395237.	TAS	Process
GO:0030742	GTP-dependent protein binding	10934204.	IPI	Function
GO:1990830	cellular response to leukemia inhibitory factor	-	IEA	Process

EuRBPDB

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.