EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr1	27012450	Missense_Mutation	novel	G74V	0.13	NTP_transf_7
BLCA	chr1	27005854	3'UTR	novel		0.29
BLCA	chr1	27006351	Missense_Mutation	rs750538687	R291W	0.2	NTP_transf_7
BLCA	chr1	27005945	Nonstop_Mutation	NA	426Sext26	0.6
BLCA	chr1	27006480	Missense_Mutation	rs777073358	E248K	0.33	NTP_transf_7
BRCA	chr1	27006606	Missense_Mutation	NA	D206H	0.28	NTP_transf_7
CESC	chr1	27006351	Missense_Mutation	rs750538687	R291W	0.24	NTP_transf_7
CESC	chr1	27006127	Silent	rs760534268	T365T	0.23
COAD	chr1	27012457	Missense_Mutation	NA	G72R	0.35	NTP_transf_7
COAD	chr1	27006229	Silent	rs371947912	F331F	0.33
COAD	chr1	27005756	3'UTR	novel		0.22
COAD	chr1	27005872	3'UTR	novel		0.4
COAD	chr1	27012495	Missense_Mutation	NA	R59Q	0.4	NTP_transf_7
COAD	chr1	27006711	Missense_Mutation	NA	E171Q	0.22	NTP_transf_7
COAD	chr1	27006602	Missense_Mutation	NA	S207W	0.28	NTP_transf_7
COAD	chr1	27005905	3'UTR	novel		0.16
COAD	chr1	27012453	Missense_Mutation	NA	R73H	0.24	NTP_transf_7
COAD	chr1	27006703	Silent	rs557466090	Y173Y	0.33
COAD	chr1	27006229	Silent	rs371947912	F331F	0.16
COAD	chr1	27006376	Silent	NA	Y282Y	0.21
COAD	chr1	27006036	Missense_Mutation	NA	D396N	0.23
ESCA	chr1	27006634	Silent	rs143879440	S196S	0.41
GBM	chr1	27006325	Silent	NA	R299R	0.62
HNSC	chr1	27006385	Silent	novel	L279L	0.33
KIRC	chr1	27005778	3'UTR	novel		0.27
KIRP	chr1	27006587	Missense_Mutation	NA	F212Y	0.31	NTP_transf_7
LAML	chr1	27006606	Missense_Mutation	NA	D206H	0.05	NTP_transf_7
LGG	chr1	27006818	Missense_Mutation	rs142455633	R135H	0.39	NTP_transf_7
LIHC	chr1	27006886	Silent	novel	S112S	0.45
LIHC	chr1	27012695	5'UTR	novel		0.25
LUAD	chr1	27012477	Missense_Mutation	NA	S65N	0.57	NTP_transf_7
LUAD	chr1	27006480	Missense_Mutation	rs777073358	E248K	0.1	NTP_transf_7
LUAD	chr1	27006562	Missense_Mutation	novel	Q220H	0.16	NTP_transf_7
LUAD	chr1	27006429	Missense_Mutation	novel	V265I	0.12	NTP_transf_7
LUAD	chr1	27006527	Missense_Mutation	NA	C232F	0.32	NTP_transf_7
LUAD	chr1	27006276	Silent	NA	L316L	0.08
LUAD	chr1	27005980	Silent	NA	L414L	0.23
LUSC	chr1	27006447	Missense_Mutation	novel	E259K	0.35	NTP_transf_7
LUSC	chr1	27006591	Missense_Mutation	novel	Q211K	0.26	NTP_transf_7
LUSC	chr1	27006025	Silent	novel	V399V	0.21
OV	chr1	27006681	Missense_Mutation	NA	C181R	0.4	NTP_transf_7
OV	chr1	27005906	3'UTR	rs777465397		0.5
PAAD	chr1	27005913	3'UTR	novel		0.2
PAAD	chr1	27006785	Missense_Mutation	novel	V146A	0.21	NTP_transf_7
READ	chr1	27006675	Missense_Mutation	rs749677149	D183N	0.44	NTP_transf_7
SKCM	chr1	27006345	Silent	novel	R293R	0.43
SKCM	chr1	27006346	Silent	novel	P292P	0.43
SKCM	chr1	27006661	Nonsense_Mutation	novel	W187*	0.41	NTP_transf_7
SKCM	chr1	27012441	Missense_Mutation	NA	P77L	0.44	NTP_transf_7
SKCM	chr1	27006760	Silent	NA	F154F	0.93
SKCM	chr1	27006358	Silent	NA	R288R	0.23
SKCM	chr1	27012441	Missense_Mutation	NA	P77L	0.73	NTP_transf_7
SKCM	chr1	27005983	Silent	NA	L413L	0.45
SKCM	chr1	27005859	3'UTR	novel		0.33
SKCM	chr1	27006172	Silent	novel	V350V	0.86
SKCM	chr1	27006805	Silent	NA	S139S	0.06
SKCM	chr1	27012537	Missense_Mutation	NA	P45L	0.15
STAD	chr1	27006416	Missense_Mutation	rs142452050	R269H	0.31	NTP_transf_7
STAD	chr1	27006343	Silent	novel	R293R	0.39
STAD	chr1	27006169	Silent	novel	N351N	0.35
STAD	chr1	27006437	Missense_Mutation	rs372912900	R262Q	0.25	NTP_transf_7
STAD	chr1	27006202	Silent	rs746985892	Y340Y	0.41
THCA	chr1	27006616	Silent	novel	L202L	0.13
UCEC	chr1	27012532	Missense_Mutation	novel	R47W	0.29
UCEC	chr1	27006470	Missense_Mutation	NA	Y251C	0.33	NTP_transf_7
UCEC	chr1	27006139	Silent	novel	E361E	0.14
UCEC	chr1	27006555	Silent	novel	L223L	0.3
UCEC	chr1	27012452	Silent	novel	R73R	0.08
UCEC	chr1	27006751	Silent	rs142664149	A157A	0.4
UCEC	chr1	27005915	3'UTR	novel		0.24
UCEC	chr1	27005873	3'UTR	novel		0.52
UCEC	chr1	27006137	Missense_Mutation	novel	R362H	0.41	NTP_transf_7
UCEC	chr1	27006783	Missense_Mutation	novel	V147M	0.45	NTP_transf_7
UCEC	chr1	27006481	Silent	novel	G247G	0.29
UCEC	chr1	27006228	Missense_Mutation	novel	G332S	0.38	NTP_transf_7
UCEC	chr1	27006951	Missense_Mutation	novel	R91S	0.26	NTP_transf_7
UCEC	chr1	27006634	Silent	rs143879440	S196S	0.22
UCEC	chr1	27006818	Missense_Mutation	rs142455633	R135H	0.19	NTP_transf_7
UCEC	chr1	27006604	Missense_Mutation	novel	D206E	0.08	NTP_transf_7
UCEC	chr1	27006345	Missense_Mutation	rs779099813	R293W	0.21	NTP_transf_7
UCEC	chr1	27006670	Silent	novel	S184S	0.27
UCEC	chr1	27006546	Missense_Mutation	novel	L226M	0.43	NTP_transf_7
UCEC	chr1	27012476	Silent	novel	S65S	0.55
UCEC	chr1	27006681	Missense_Mutation	NA	C181R	0.33	NTP_transf_7
UCEC	chr1	27006680	Missense_Mutation	novel	C181Y	0.5	NTP_transf_7
UCEC	chr1	27006202	Silent	rs746985892	Y340Y	0.27
UCEC	chr1	27006360	Missense_Mutation	NA	R288W	0.24	NTP_transf_7
UCEC	chr1	27006602	Missense_Mutation	rs779739476	S207L	0.35	NTP_transf_7
UCEC	chr1	27006702	Missense_Mutation	novel	V174M	0.26	NTP_transf_7
UCEC	chr1	27005805	3'UTR	novel		0.44
UCEC	chr1	27006552	Missense_Mutation	NA	D224N	0.22	NTP_transf_7
UCEC	chr1	27006142	Silent	rs190999684	H360H	0.17
UCEC	chr1	27012565	Frame_Shift_Del	novel	*T28Pfs14**	0.63
UCEC	chr1	27006593	Missense_Mutation	rs758921194	R210H	0.37	NTP_transf_7

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
CESC	DEL	0.0949	0.00029523
CHOL	DEL	0.8056	3.3987e-23
COAD	DEL	0.3237	4.7302e-24
DLBC	DEL	0.1042	0.011841
ESCA	DEL	0.2989	0.0012162
HNSC	DEL	0.1379	7.0766e-07
KIRC	DEL	0.1515	2.3538e-09
KIRP	DEL	0.1736	1.462e-09
LIHC	DEL	0.3541	1.6679e-20
LUAD	DEL	0.1686	0.0024765
LUSC	DEL	0.3693	2.5882e-07
MESO	DEL	0.2644	2.434e-07
OV	DEL	0.4162	3.6326e-35
PAAD	DEL	0.288	3.1088e-06
READ	DEL	0.4061	2.1758e-10
TGCT	DEL	0.16	0.00046313
UCEC	DEL	0.1391	1.9002e-17

Survival Analysis

Cancer	P-value	Q-value
MESO	0.015	Kaplan-Meier Survival Analysis
ACC	0.012	Kaplan-Meier Survival Analysis
HNSC	0.049	Kaplan-Meier Survival Analysis
SKCM	0.02	Kaplan-Meier Survival Analysis
LUSC	0.0066	Kaplan-Meier Survival Analysis
KIRP	0.022	Kaplan-Meier Survival Analysis
BLCA	0.039	Kaplan-Meier Survival Analysis
LAML	0.02	Kaplan-Meier Survival Analysis
UCEC	0.029	Kaplan-Meier Survival Analysis
GBM	0.018	Kaplan-Meier Survival Analysis
LIHC	0.0033	Kaplan-Meier Survival Analysis
LUAD	0.05	Kaplan-Meier Survival Analysis
OV	0.017	Kaplan-Meier Survival Analysis

Description

RBDs

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000158246 (Gene tree)
Gene ID: 115572
Gene Symbol: TENT5B
Alias: MGC16491|FAM46B
Full Name: terminal nucleotidyltransferase 5B
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 7,823 bases
Position: chr1:27,005,020-27,012,842
Accession: 28273
RBP type: canonical RBP
Summary: TENT5B (Terminal Nucleotidyltransferase 5B) is a Protein Coding gene. An important paralog of this gene is TENT5A.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000289166	NTP_transf_7	PF07984.12	2.1e-149	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000289166	TENT5B-201	2368	-	ENSP00000289166	425 (aa)	-	Q96A09

Gene Model

Click here to download ENSG00000158246's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000158246's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000158246	TENT5B	100	90.255	ENSAMEG00000010835	TENT5B	100	90.164	Ailuropoda_melanoleuca
ENSG00000158246	TENT5B	72	70.513	ENSAPLG00000001361	TENT5B	100	70.513	Anas_platyrhynchos
ENSG00000158246	TENT5B	89	71.391	ENSACAG00000016761	TENT5B	89	71.391	Anolis_carolinensis
ENSG00000158246	TENT5B	92	97.704	ENSANAG00000028081	TENT5B	100	97.704	Aotus_nancymaae
ENSG00000158246	TENT5B	100	91.628	ENSBTAG00000018413	TENT5B	100	91.628	Bos_taurus
ENSG00000158246	TENT5B	100	96.235	ENSCJAG00000010081	TENT5B	85	96.235	Callithrix_jacchus
ENSG00000158246	TENT5B	100	92.037	ENSCAFG00000028558	TENT5B	100	92.037	Canis_familiaris
ENSG00000158246	TENT5B	100	92.037	ENSCAFG00020021681	TENT5B	100	92.037	Canis_lupus_dingo
ENSG00000158246	TENT5B	100	91.628	ENSCHIG00000019519	TENT5B	100	91.628	Capra_hircus
ENSG00000158246	TENT5B	100	89.930	ENSTSYG00000035698	TENT5B	100	89.930	Carlito_syrichta
ENSG00000158246	TENT5B	80	92.353	ENSCAPG00000015837	TENT5B	95	92.353	Cavia_aperea
ENSG00000158246	TENT5B	100	88.993	ENSCPOG00000032542	TENT5B	100	89.227	Cavia_porcellus
ENSG00000158246	TENT5B	100	95.765	ENSCCAG00000036493	TENT5B	100	95.765	Cebus_capucinus
ENSG00000158246	TENT5B	100	97.882	ENSCATG00000017109	TENT5B	100	97.882	Cercocebus_atys
ENSG00000158246	TENT5B	100	89.696	ENSCLAG00000010180	TENT5B	100	88.993	Chinchilla_lanigera
ENSG00000158246	TENT5B	100	97.647	ENSCSAG00000000987	TENT5B	100	97.647	Chlorocebus_sabaeus
ENSG00000158246	TENT5B	94	69.307	ENSCPBG00000024956	TENT5B	96	71.429	Chrysemys_picta_bellii
ENSG00000158246	TENT5B	100	98.824	ENSCANG00000027512	TENT5B	100	98.824	Colobus_angolensis_palliatus
ENSG00000158246	TENT5B	100	90.164	ENSCGRG00001024770	Tent5b	100	90.164	Cricetulus_griseus_chok1gshd
ENSG00000158246	TENT5B	80	91.837	ENSCGRG00000003851	Tent5b	91	92.375	Cricetulus_griseus_crigri
ENSG00000158246	TENT5B	100	89.227	ENSDNOG00000046099	TENT5B	100	89.227	Dasypus_novemcinctus
ENSG00000158246	TENT5B	99	90.465	ENSDORG00000015648	Tent5b	99	90.233	Dipodomys_ordii
ENSG00000158246	TENT5B	99	89.671	ENSETEG00000006030	TENT5B	100	89.671	Echinops_telfairi
ENSG00000158246	TENT5B	94	64.706	ENSEBUG00000005702	TENT5B	60	64.706	Eptatretus_burgeri
ENSG00000158246	TENT5B	99	92.958	ENSEASG00005008682	TENT5B	84	92.958	Equus_asinus_asinus
ENSG00000158246	TENT5B	99	93.427	ENSECAG00000018835	TENT5B	84	93.427	Equus_caballus
ENSG00000158246	TENT5B	99	89.461	ENSEEUG00000011429	TENT5B	100	89.461	Erinaceus_europaeus
ENSG00000158246	TENT5B	100	92.506	ENSFCAG00000010300	TENT5B	100	92.506	Felis_catus
ENSG00000158246	TENT5B	80	71.930	ENSFALG00000014519	TENT5B	99	71.930	Ficedula_albicollis
ENSG00000158246	TENT5B	88	93.351	ENSFDAG00000000679	TENT5B	100	93.351	Fukomys_damarensis
ENSG00000158246	TENT5B	97	67.308	ENSGALG00000036117	TENT5B	90	69.767	Gallus_gallus
ENSG00000158246	TENT5B	89	71.654	ENSGAGG00000004814	TENT5B	99	70.769	Gopherus_agassizii
ENSG00000158246	TENT5B	100	99.529	ENSGGOG00000008075	FAM46B	100	99.529	Gorilla_gorilla
ENSG00000158246	TENT5B	100	90.164	ENSHGLG00000010460	-	100	89.461	Heterocephalus_glaber_female
ENSG00000158246	TENT5B	100	83.372	ENSHGLG00000008692	-	100	82.670	Heterocephalus_glaber_female
ENSG00000158246	TENT5B	100	85.480	ENSHGLG00100013467	-	100	84.778	Heterocephalus_glaber_male
ENSG00000158246	TENT5B	84	87.989	ENSHGLG00100002251	-	100	80.094	Heterocephalus_glaber_male
ENSG00000158246	TENT5B	100	89.302	ENSSTOG00000022787	TENT5B	100	91.395	Ictidomys_tridecemlineatus
ENSG00000158246	TENT5B	100	89.930	ENSJJAG00000017789	-	100	89.930	Jaculus_jaculus
ENSG00000158246	TENT5B	95	80.098	ENSJJAG00000016845	-	95	81.330	Jaculus_jaculus
ENSG00000158246	TENT5B	100	92.506	ENSLAFG00000023075	TENT5B	100	92.506	Loxodonta_africana
ENSG00000158246	TENT5B	100	98.118	ENSMFAG00000003756	TENT5B	100	98.118	Macaca_fascicularis
ENSG00000158246	TENT5B	100	98.118	ENSMMUG00000015115	TENT5B	100	98.118	Macaca_mulatta
ENSG00000158246	TENT5B	100	98.353	ENSMNEG00000042604	TENT5B	100	98.353	Macaca_nemestrina
ENSG00000158246	TENT5B	100	94.588	ENSMLEG00000042465	TENT5B	100	94.588	Mandrillus_leucophaeus
ENSG00000158246	TENT5B	83	69.101	ENSMGAG00000016174	TENT5B	100	69.101	Meleagris_gallopavo
ENSG00000158246	TENT5B	100	91.335	ENSMAUG00000014675	Tent5b	100	91.335	Mesocricetus_auratus
ENSG00000158246	TENT5B	100	93.911	ENSMICG00000033781	TENT5B	100	93.911	Microcebus_murinus
ENSG00000158246	TENT5B	100	89.696	ENSMOCG00000006029	Tent5b	100	89.696	Microtus_ochrogaster
ENSG00000158246	TENT5B	92	78.446	ENSMODG00000014427	TENT5B	86	74.771	Monodelphis_domestica
ENSG00000158246	TENT5B	100	91.335	MGP_CAROLIEiJ_G0026589	Tent5b	100	91.335	Mus_caroli
ENSG00000158246	TENT5B	100	91.335	ENSMUSG00000046694	Tent5b	100	91.335	Mus_musculus
ENSG00000158246	TENT5B	100	92.037	MGP_PahariEiJ_G0028922	Tent5b	100	92.037	Mus_pahari
ENSG00000158246	TENT5B	100	91.569	MGP_SPRETEiJ_G0027570	Tent5b	100	91.569	Mus_spretus
ENSG00000158246	TENT5B	100	91.335	ENSMPUG00000015656	TENT5B	100	91.335	Mustela_putorius_furo
ENSG00000158246	TENT5B	100	90.421	ENSMLUG00000004676	TENT5B	100	90.421	Myotis_lucifugus
ENSG00000158246	TENT5B	100	90.867	ENSNGAG00000010187	Tent5b	85	90.867	Nannospalax_galili
ENSG00000158246	TENT5B	100	98.824	ENSNLEG00000009432	TENT5B	100	98.824	Nomascus_leucogenys
ENSG00000158246	TENT5B	92	75.689	ENSMEUG00000011770	TENT5B	100	72.248	Notamacropus_eugenii
ENSG00000158246	TENT5B	99	85.648	ENSOPRG00000016453	TENT5B	100	85.185	Ochotona_princeps
ENSG00000158246	TENT5B	100	88.759	ENSODEG00000003616	TENT5B	100	88.993	Octodon_degus
ENSG00000158246	TENT5B	99	93.458	ENSOCUG00000006426	TENT5B	100	93.458	Oryctolagus_cuniculus
ENSG00000158246	TENT5B	100	91.803	ENSOGAG00000002086	TENT5B	100	91.803	Otolemur_garnettii
ENSG00000158246	TENT5B	100	91.628	ENSOARG00000003875	TENT5B	100	91.628	Ovis_aries
ENSG00000158246	TENT5B	96	96.806	ENSPPAG00000035934	TENT5B	98	96.806	Pan_paniscus
ENSG00000158246	TENT5B	100	92.740	ENSPPRG00000023756	TENT5B	100	92.740	Panthera_pardus
ENSG00000158246	TENT5B	61	94.574	ENSPTIG00000014641	TENT5B	72	94.574	Panthera_tigris_altaica
ENSG00000158246	TENT5B	100	99.529	ENSPTRG00000000397	TENT5B	100	99.529	Pan_troglodytes
ENSG00000158246	TENT5B	100	98.353	ENSPANG00000007821	TENT5B	100	98.353	Papio_anubis
ENSG00000158246	TENT5B	80	71.637	ENSPSIG00000000566	TENT5B	100	71.637	Pelodiscus_sinensis
ENSG00000158246	TENT5B	99	86.682	ENSPPYG00000001670	TENT5B	100	86.682	Pongo_abelii
ENSG00000158246	TENT5B	99	90.845	ENSPCAG00000002766	TENT5B	100	90.845	Procavia_capensis
ENSG00000158246	TENT5B	100	93.443	ENSPCOG00000011763	TENT5B	100	93.443	Propithecus_coquereli
ENSG00000158246	TENT5B	53	87.324	ENSPVAG00000004419	-	54	87.324	Pteropus_vampyrus
ENSG00000158246	TENT5B	100	91.101	ENSRNOG00000056153	Tent5b	100	91.101	Rattus_norvegicus
ENSG00000158246	TENT5B	100	98.588	ENSRBIG00000033865	TENT5B	100	98.588	Rhinopithecus_bieti
ENSG00000158246	TENT5B	100	98.588	ENSRROG00000045423	TENT5B	100	98.588	Rhinopithecus_roxellana
ENSG00000158246	TENT5B	100	95.529	ENSSBOG00000023376	TENT5B	100	95.529	Saimiri_boliviensis_boliviensis
ENSG00000158246	TENT5B	99	74.413	ENSSARG00000003874	TENT5B	100	74.413	Sorex_araneus
ENSG00000158246	TENT5B	94	68.642	ENSSPUG00000018249	TENT5B	94	71.391	Sphenodon_punctatus
ENSG00000158246	TENT5B	100	85.748	ENSSSCG00000036755	TENT5B	100	85.748	Sus_scrofa
ENSG00000158246	TENT5B	88	70.899	ENSTGUG00000000977	TENT5B	99	70.899	Taeniopygia_guttata
ENSG00000158246	TENT5B	99	92.488	ENSTBEG00000002227	TENT5B	100	92.488	Tupaia_belangeri
ENSG00000158246	TENT5B	79	91.471	ENSTTRG00000006556	TENT5B	100	91.471	Tursiops_truncatus
ENSG00000158246	TENT5B	100	92.740	ENSUAMG00000005925	TENT5B	100	92.740	Ursus_americanus
ENSG00000158246	TENT5B	58	94.332	ENSUMAG00000011875	TENT5B	65	94.332	Ursus_maritimus
ENSG00000158246	TENT5B	100	92.037	ENSVVUG00000012066	TENT5B	100	92.037	Vulpes_vulpes
ENSG00000158246	TENT5B	88	68.504	ENSXETG00000020683	tent5b	96	68.504	Xenopus_tropicalis

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005515	protein binding	16189514.16713569.19060904.23275563.25416956.25814554.	IPI	Function
GO:1990817	RNA adenylyltransferase activity	-	IEA	Function

Note: Click here to get the extension of tumor abbreviations.

Note: to get the extension of tumor abbreviations.