EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
29807573	Cell cycle and apoptosis regulator 2 at the interface between DNA damage response and cell physiology.	Mutat Res	2018 Apr - Jun	Magni M	doi: 10.1016/j.mrrev.2018.03.004
18235502	Negative regulation of the deacetylase SIRT1 by DBC1.	Nature	2008 Jan 31	Zhao W	doi: 10.1038/nature06515.
22127596	The overexpression of DBC1 in esophageal squamous cell carcinoma correlates with poor prognosis.	Histol Histopathol	2012 Jan	Kim SH	doi: 10.14670/HH-27.49.
26617872	High DBC1 (CCAR2) expression in gallbladder carcinoma is associated with favorable clinicopathological factors.	Int J Clin Exp Pathol	2015 Sep 1	Won KY	-
15824730	Caspase-dependent processing activates the proapoptotic activity of deleted in breast cancer-1 during tumor necrosis factor-alpha-mediated death signaling.	Oncogene	2005 Jul 21	Sundararajan R	-
27809307	A novel crosstalk between CCAR2 and AKT pathway in the regulation of cancer cell proliferation.	Cell Death Dis	2016 Nov 3	Restelli M	doi: 10.1038/cddis.2016.359.
19126541	Deleted in breast cancer 1, a novel androgen receptor (AR) coactivator that promotes AR DNA-binding activity.	J Biol Chem	2009 Mar 13	Fu J	doi: 10.1074/jbc.M808988200
23299276	DBC1 is over-expressed and associated with poor prognosis in colorectal cancer.	Int J Clin Oncol	2014 Feb	Zhang Y	doi: 10.1007/s10147-012-0506-5
17473282	Modulation of estrogen receptor alpha protein level and survival function by DBC-1.	Mol Endocrinol	2007 Jul	Trauernicht AM	-
23841676	Deleted in breast cancer-1 (DBC-1) in the interface between metabolism, aging and cancer.	Biosci Rep	2013 Aug 23	Chini EN	doi: 10.1042/BSR20130062.
26035299	DBC1 promotes anoikis resistance of gastric cancer cells by regulating NF-??B activity.	Oncol Rep	2015 Aug	Huan Y	doi: 10.3892/or.2015.4007
29249800	DBC1 promotes castration-resistant prostate cancer by positively regulating DNA binding and stability of AR-V7.	Oncogene	2018 Mar	Moon SJ	doi: 10.1038/s41388-017-0047-5

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr8	22617717	Missense_Mutation	rs761013874	S671L	0.37
BLCA	chr8	22617717	Missense_Mutation	rs761013874	S671L	0.24
BLCA	chr8	22618361	Missense_Mutation	novel	D696N	0.92
BLCA	chr8	22606114	Missense_Mutation	novel	P30S	0.35
BLCA	chr8	22617706	Silent	NA	K667K	0.05
BRCA	chr8	22607244	Missense_Mutation	NA	G136R	0.15
BRCA	chr8	22613039	Missense_Mutation	NA	R203C	0.2
BRCA	chr8	22618946	Missense_Mutation	novel	R818C	0.26
BRCA	chr8	22620045	3'UTR	novel		0.25
BRCA	chr8	22607312	Silent	NA	L158L	0.15
BRCA	chr8	22618853	Frame_Shift_Del	NA	*S789Afs21**	0.42
CESC	chr8	22620402	3'UTR	novel		0.26
CESC	chr8	22619655	Silent	novel	E915E	0.63
CESC	chr8	22619950	3'UTR	novel		0.43
CESC	chr8	22621077	3'UTR	rs144962194		0.38
CESC	chr8	22621276	3'UTR	novel		0.32
CESC	chr8	22613106	Missense_Mutation	rs200429085	R225Q	0.34
CESC	chr8	22621326	3'UTR	novel		0.42
CESC	chr8	22606652	Missense_Mutation	novel	H66N	0.83	S1-like
CESC	chr8	22606653	Missense_Mutation	novel	H66L	0.83	S1-like
CESC	chr8	22614876	Silent	novel	V360V	0.39
CESC	chr8	22615835	Missense_Mutation	rs549430841	A511T	0.29
CESC	chr8	22619749	3'UTR	rs201138536		0.4
CESC	chr8	22605820	Missense_Mutation	NA	R16H	0.2
CESC	chr8	22620173	3'UTR	novel		0.24
COAD	chr8	22614945	Silent	rs115014172	T383T	0.39
COAD	chr8	22605820	Missense_Mutation	NA	R16H	0.33
COAD	chr8	22614934	Silent	novel	L380L	0.27
COAD	chr8	22619311	Missense_Mutation	rs556131395	R895C	0.19
COAD	chr8	22615811	Frame_Shift_Del	NA	L505*	0.27
COAD	chr8	22615811	Frame_Shift_Del	NA	L505*	0.08
COAD	chr8	22605820	Missense_Mutation	NA	R16H	0.16
COAD	chr8	22614981	Missense_Mutation	novel	D395E	0.08
COAD	chr8	22619587	Intron	novel		0.38
COAD	chr8	22614225	Missense_Mutation	rs778848959	R280W	0.37
COAD	chr8	22621415	3'UTR	novel		0.63
COAD	chr8	22615811	Frame_Shift_Del	NA	L505*	0.25
COAD	chr8	22619665	Missense_Mutation	NA	P919S	0.39
COAD	chr8	22607011	Missense_Mutation	novel	T115M	0.18
COAD	chr8	22615462	Frame_Shift_Del	NA	*R417Gfs89**	0.26
COAD	chr8	22615811	Frame_Shift_Del	NA	L505*	0.16
COAD	chr8	22615462	Frame_Shift_Del	NA	*R417Gfs89**	0.23
COAD	chr8	22616225	Missense_Mutation	novel	A608T	0.24
COAD	chr8	22618651	Missense_Mutation	novel	N752S	0.09
COAD	chr8	22606100	Missense_Mutation	novel	S25F	0.16
COAD	chr8	22615811	Frame_Shift_Del	NA	L505*	0.17
COAD	chr8	22606684	Frame_Shift_Ins	novel	*Q79Sfs14**	0.23	S1-like
COAD	chr8	22615462	Frame_Shift_Del	NA	*R417Gfs89**	0.28
DLBC	chr8	22614978	Silent	novel	I394I	0.3
ESCA	chr8	22613040	Missense_Mutation	rs773478671	R203H	0.12
ESCA	chr8	22615721	Nonsense_Mutation	novel	Q473*	0.54
ESCA	chr8	22619900	3'UTR	novel		0.18
ESCA	chr8	22616104	Silent	novel	V567V	0.27
ESCA	chr8	22619300	Frame_Shift_Ins	novel	*R894Sfs5**	0.22
GBM	chr8	22607976	Missense_Mutation	novel	S165R	0.18
GBM	chr8	22608062	Missense_Mutation	novel	R194Q	0.25
GBM	chr8	22614927	Silent	rs13250541	P377P	0.39
GBM	chr8	22615831	Silent	novel	V509V	0.23
GBM	chr8	22617511	Missense_Mutation	novel	M646R	0.28
HNSC	chr8	22616237	Missense_Mutation	novel	E612K	0.29
HNSC	chr8	22621364	3'UTR	novel		0.71
KIRC	chr8	22618658	Silent	novel	C754C	0.06
KIRP	chr8	22617429	Frame_Shift_Del	novel	*L620Ffs36**	0.15
KIRP	chr8	22606641	Missense_Mutation	NA	V62D	0.32	S1-like
KIRP	chr8	22616151	Missense_Mutation	NA	A583V	0.28
LIHC	chr8	22614249	Missense_Mutation	NA	E288Q	0.67
LIHC	chr8	22619254	Missense_Mutation	NA	R876G	0.46
LUAD	chr8	22617460	Missense_Mutation	novel	G629A	0.08
LUAD	chr8	22617778	Missense_Mutation	novel	M691I	0.28
LUAD	chr8	22606971	Missense_Mutation	NA	P102S	0.51
LUAD	chr8	22605745	5'UTR	novel		0.09
LUAD	chr8	22613114	Missense_Mutation	novel	L228F	0.09
LUSC	chr8	22615798	Silent	novel	P498P	0.31
LUSC	chr8	22606655	Missense_Mutation	novel	D67H	0.12	S1-like
LUSC	chr8	22606105	Silent	novel	L27L	0.19
LUSC	chr8	22607293	Missense_Mutation	NA	P152L	0.28
LUSC	chr8	22616104	Silent	novel	V567V	0.59
OV	chr8	22618407	Missense_Mutation	novel	F711Y	0.59
OV	chr8	22616233	Missense_Mutation	novel	E610D	0.25
OV	chr8	22618452	Missense_Mutation	novel	E726V	0.41
OV	chr8	22618424	Missense_Mutation	NA	C717G	0.24
OV	chr8	22606135	Missense_Mutation	NA	P37S	0.51
PAAD	chr8	22617749	Nonsense_Mutation	novel	E682*	0.14
PRAD	chr8	22606912	Missense_Mutation	NA	V82A	0.48
PRAD	chr8	22615446	Silent	NA	Q409Q	0.19
PRAD	chr8	22608030	Silent	novel	A183A	0.34
PRAD	chr8	22615430	Missense_Mutation	novel	R404H	0.28
READ	chr8	22615836	Missense_Mutation	NA	A511E	0.23
READ	chr8	22614941	Missense_Mutation	NA	R382H	0.12
READ	chr8	22615811	Frame_Shift_Del	NA	L505*	0.24
READ	chr8	22613035	Missense_Mutation	novel	K201N	0.36
SKCM	chr8	22617432	Missense_Mutation	NA	L620F	0.43
SKCM	chr8	22614952	Missense_Mutation	novel	R386C	0.56
SKCM	chr8	22617479	Silent	rs201166271	P635P	0.88
SKCM	chr8	22616033	Missense_Mutation	NA	F544L	0.13
SKCM	chr8	22613104	Silent	rs748101316	Y224Y	0.3
SKCM	chr8	22613105	Missense_Mutation	rs769599381	R225W	0.33
SKCM	chr8	22615459	Missense_Mutation	NA	G414R	0.31
SKCM	chr8	22617724	Silent	NA	V673V	0.44
SKCM	chr8	22614238	Missense_Mutation	novel	S284F	0.22
SKCM	chr8	22616034	Missense_Mutation	NA	F544C	0.48
SKCM	chr8	22615755	Missense_Mutation	novel	T484I	0.14
SKCM	chr8	22613121	Missense_Mutation	NA	P230L	0.28
SKCM	chr8	22608023	Missense_Mutation	novel	F181C	0.46
SKCM	chr8	22615541	Missense_Mutation	novel	A441V	0.12
SKCM	chr8	22615542	Silent	rs140743871	A441A	0.12
SKCM	chr8	22607317	Missense_Mutation	novel	P160L	0.28
SKCM	chr8	22607319	Nonsense_Mutation	novel	Q161*	0.27
SKCM	chr8	22618427	Missense_Mutation	NA	G718S	0.22
STAD	chr8	22615462	Frame_Shift_Del	NA	*R417Gfs89**	0.28
STAD	chr8	22605820	Missense_Mutation	NA	R16H	0.13
STAD	chr8	22618837	Missense_Mutation	NA	D781E	0.07
STAD	chr8	22615470	Silent	NA	R417R	0.06
STAD	chr8	22617734	Missense_Mutation	novel	A677T	0.15
STAD	chr8	22618844	Frame_Shift_Del	NA	*P785Lfs25**	0.13
STAD	chr8	22619016	Splice_Site	NA	X841_splice	0.18
STAD	chr8	22608034	Missense_Mutation	novel	G185S	0.31
STAD	chr8	22615462	Frame_Shift_Del	NA	*R417Gfs89**	0.16
STAD	chr8	22615748	Missense_Mutation	rs748696165	A482T	0.1
STAD	chr8	22614186	Missense_Mutation	NA	F267V	0.3
STAD	chr8	22615727	Missense_Mutation	NA	A475T	0.18
STAD	chr8	22607284	Missense_Mutation	NA	I149T	0.15
STAD	chr8	22618713	Missense_Mutation	NA	E773K	0.21
STAD	chr8	22615747	Silent	rs151294361	N481N	0.07
STAD	chr8	22615462	Frame_Shift_Del	NA	*R417Gfs89**	0.36
STAD	chr8	22618941	Missense_Mutation	NA	L816P	0.05
STAD	chr8	22617699	Missense_Mutation	rs201118681	G665E	0.25
STAD	chr8	22606125	Silent	NA	L33L	0.45
STAD	chr8	22615462	Frame_Shift_Del	NA	*R417Gfs89**	0.17
STAD	chr8	22617481	Missense_Mutation	NA	R636L	0.14
STAD	chr8	22615462	Frame_Shift_Del	NA	*R417Gfs89**	0.21
STAD	chr8	22616110	Silent	NA	S569S	0.24
STAD	chr8	22615462	Frame_Shift_Del	NA	*R417Gfs89**	0.11
STAD	chr8	22615835	Missense_Mutation	rs549430841	A511T	0.15
STAD	chr8	22615811	Frame_Shift_Del	NA	L505*	0.27
THCA	chr8	22619152	Nonsense_Mutation	NA	E842*	0.2
THYM	chr8	22618488	Missense_Mutation	novel	A738V	0.17
UCEC	chr8	22616184	Missense_Mutation	novel	V594A	0.44
UCEC	chr8	22617468	Nonsense_Mutation	NA	E632*	0.26
UCEC	chr8	22618357	Missense_Mutation	novel	E694D	0.43
UCEC	chr8	22618497	Splice_Site	novel	X740_splice	0.31
UCEC	chr8	22615811	Frame_Shift_Del	NA	L505*	0.45
UCEC	chr8	22604781	5'UTR	novel		0.25
UCEC	chr8	22620132	3'UTR	novel		0.4
UCEC	chr8	22614300	Missense_Mutation	NA	A305T	0.26
UCEC	chr8	22615730	Missense_Mutation	novel	D476N	0.33
UCEC	chr8	22619287	Missense_Mutation	novel	R887W	0.44
UCEC	chr8	22619730	3'UTR	novel		0.43
UCEC	chr8	22605806	Silent	rs150400388	P11P	0.22
UCEC	chr8	22619647	Missense_Mutation	NA	W913R	0.4
UCEC	chr8	22619222	Missense_Mutation	NA	R865Q	0.29
UCEC	chr8	22615471	Missense_Mutation	rs200285926	R418W	0.39
UCEC	chr8	22614946	Missense_Mutation	rs368135137	A384T	0.55
UCEC	chr8	22614475	Missense_Mutation	rs199827847	T338M	0.1
UCEC	chr8	22620299	3'UTR	novel		0.38
UCEC	chr8	22606626	Missense_Mutation	novel	V57A	0.33	S1-like
UCEC	chr8	22614310	Missense_Mutation	novel	S308L	0.22
UCEC	chr8	22618354	Missense_Mutation	novel	K693N	0.07
UCEC	chr8	22614314	Missense_Mutation	novel	K309N	0.27
UCEC	chr8	22620263	3'UTR	novel		0.09
UCEC	chr8	22620448	3'UTR	novel		0.5
UCEC	chr8	22608032	Missense_Mutation	novel	R184Q	0.3
UCEC	chr8	22616131	Frame_Shift_Del	NA	*E577Rfs39**	0.28
UCEC	chr8	22608020	Missense_Mutation	novel	R180I	0.5
UCEC	chr8	22619691	3'UTR	novel		0.1
UCEC	chr8	22606666	Silent	novel	G70G	0.66
UCEC	chr8	22618951	Silent	rs189318060	A819A	0.43
UCEC	chr8	22619261	Missense_Mutation	rs769836001	A878V	0.33
UCEC	chr8	22614995	Missense_Mutation	rs199704953	T400I	0.28
UCEC	chr8	22615462	Frame_Shift_Del	NA	*R417Gfs89**	0.5
UCEC	chr8	22615808	Missense_Mutation	novel	P502T	0.56
UCEC	chr8	22615461	Frame_Shift_Ins	rs756536005	*R417Pfs49**	0.64
UCEC	chr8	22618396	Silent	NA	L707L	0.4
UCEC	chr8	22614148	Frame_Shift_Del	novel	S254*	0.24
UCEC	chr8	22620182	3'UTR	novel		0.09
UCEC	chr8	22620989	3'UTR	novel		0.31
UCEC	chr8	22605777	Missense_Mutation	NA	S2P	0.37
UCEC	chr8	22619364	Intron	novel		0.14
UCEC	chr8	22607012	Silent	novel	T115T	0.31
UCEC	chr8	22621110	3'UTR	novel		0.35
UCEC	chr8	22618971	Missense_Mutation	novel	R826Q	0.33
UCEC	chr8	22615462	Frame_Shift_Del	NA	*R417Gfs89**	0.17
UCEC	chr8	22618399	Silent	novel	A708A	0.37
UCEC	chr8	22620037	3'UTR	rs200824128		0.29
UCEC	chr8	22614477	Missense_Mutation	novel	P339S	0.29
UCEC	chr8	22605806	Silent	rs150400388	P11P	0.38
UCEC	chr8	22617519	Missense_Mutation	novel	D649N	0.06
UCEC	chr8	22615742	Missense_Mutation	rs200784385	R480W	0.21
UCEC	chr8	22605823	Missense_Mutation	novel	N17T	0.21
UCEC	chr8	22606682	Missense_Mutation	novel	V76I	0.06	S1-like
UCEC	chr8	22615839	Missense_Mutation	rs201363003	R512H	0.29
UCEC	chr8	22617725	Missense_Mutation	novel	R674W	0.09
UCEC	chr8	22617514	Missense_Mutation	NA	A647V	0.4
UCEC	chr8	22615462	Frame_Shift_Del	NA	*R417Gfs89**	0.47
UCEC	chr8	22607295	Missense_Mutation	NA	H153Y	0.3
UCEC	chr8	22614098	Silent	novel	I237I	0.18
UCEC	chr8	22614476	Silent	novel	T338T	0.43
UCEC	chr8	22615884	Missense_Mutation	novel	R527Q	0.18
UCEC	chr8	22618947	Missense_Mutation	rs201059451	R818H	0.32
UCEC	chr8	22608032	Missense_Mutation	novel	R184P	0.56
UCEC	chr8	22615462	Frame_Shift_Del	NA	*R417Gfs89**	0.45
UCEC	chr8	22618685	Silent	novel	R763R	0.42
UCEC	chr8	22616170	Silent	rs200515077	A589A	0.32
UCEC	chr8	22614204	Missense_Mutation	NA	F273L	0.24
UCEC	chr8	22615884	Missense_Mutation	novel	R527Q	0.3
UCEC	chr8	22618901	Missense_Mutation	novel	V803M	0.32
UCEC	chr8	22619683	3'UTR	rs201360936		0.33
UCEC	chr8	22621129	3'UTR	novel		0.09
UCEC	chr8	22615486	Missense_Mutation	rs755104363	V423M	0.4
UCEC	chr8	22615884	Missense_Mutation	novel	R527Q	0.34
UCS	chr8	22618949	Missense_Mutation	novel	A819T	0.5
UVM	chr8	22618449	Frame_Shift_Ins	novel	*E726Rfs86**	0.27

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BLCA	DEL	0.5711	4.5185e-08
CHOL	DEL	0.3333	0.067545
DLBC	DEL	0.25	0.15679
ESCA	DEL	0.413	0.060925
LAML	DEL	0.0052	0.24147
LIHC	DEL	0.6838	0.12467
PAAD	DEL	0.25	0.050455
PRAD	AMP	0.0163	0.059049
PRAD	DEL	0.565	5.8548e-30
READ	DEL	0.5758	0.20625
THCA	DEL	0.008	0.24038
THYM	DEL	0.0081	0.022012
UCEC	DEL	0.2022	1.6228e-10
UCS	DEL	0.5357	0.089783

Survival Analysis

Cancer	P-value	Q-value
THYM	0.0081	Kaplan-Meier Survival Analysis
STAD	0.02	Kaplan-Meier Survival Analysis
MESO	0.0024	Kaplan-Meier Survival Analysis
ACC	0.027	Kaplan-Meier Survival Analysis
HNSC	0.027	Kaplan-Meier Survival Analysis
BRCA	0.05	Kaplan-Meier Survival Analysis
COAD	0.013	Kaplan-Meier Survival Analysis
PAAD	0.035	Kaplan-Meier Survival Analysis
KICH	0.024	Kaplan-Meier Survival Analysis
CHOL	0.042	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000158941 (Gene tree)
Gene ID: 57805
Gene Symbol: CCAR2
Alias: DBC-1|DBC1|NET35|KIAA1967
Full Name: cell cycle and apoptosis regulator 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 16,883 bases
Position: chr8:22,604,632-22,621,514
Accession: 23360
RBP type: canonical RBP
Summary: (Cell Cycle And Apoptosis Regulator 2) is a Protein Coding gene. Diseases associated with CCAR2 include Estrogen-Receptor Negative Breast Cancer. Among its related pathways are Chromatin Regulation / Acetylation and DNA Damage. Gene Ontology (GO) annotations related to this gene include enzyme inhibitor activity. An important paralog of this gene is CCAR1.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000431046	S1-like	PF14444.6	7.3e-28	1	1
ENSP00000430978	S1-like	PF14444.6	7.8e-28	1	1
ENSP00000428843	S1-like	PF14444.6	9e-28	1	1
ENSP00000430974	S1-like	PF14444.6	1.1e-27	1	1
ENSP00000310670	S1-like	PF14444.6	8.1e-27	1	1
ENSP00000373930	S1-like	PF14444.6	8.1e-27	1	1
ENSP00000429769	S1-like	PF14444.6	5.8e-11	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	NascentRICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
18418069	Analysis of DBC1 and its homologs suggests a potential mechanism for regulation of sirtuin domain deacetylases by NAD metabolites.	Cell Cycle	2008 May 15	Anantharaman V	-
25661920	CCAR2 negatively regulates nuclear receptor LXRα by competing with SIRT1 deacetylase.	J Steroid Biochem Mol Biol	2015 May	Sakurabashi A	doi: 10.1016/j.jsbmb.2015.02.001

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000521837	CCAR2-210	549	-	ENSP00000430978	150 (aa)	-	E5RGU7
ENST00000521436	CCAR2-209	1840	-	-	- (aa)	-	-
ENST00000520861	CCAR2-206	3560	-	ENSP00000429773	598 (aa)	-	G3V119
ENST00000520536	CCAR2-204	2173	-	-	- (aa)	-	-
ENST00000522599	CCAR2-211	1107	-	ENSP00000429739	277 (aa)	-	E5RHJ4
ENST00000520738	CCAR2-205	2633	-	ENSP00000428549	615 (aa)	-	H0YB24
ENST00000521020	CCAR2-207	614	-	-	- (aa)	-	-
ENST00000523349	CCAR2-212	542	-	ENSP00000428843	162 (aa)	-	E5RFJ3
ENST00000521301	CCAR2-208	337	-	ENSP00000429769	81 (aa)	-	E5RHH8
ENST00000518989	CCAR2-203	453	-	ENSP00000431046	148 (aa)	-	H0YC69
ENST00000523801	CCAR2-213	549	-	ENSP00000430974	183 (aa)	-	H0YC58
ENST00000389279	CCAR2-202	3980	XM_017013717	ENSP00000373930	923 (aa)	-	Q8N163
ENST00000613179	CCAR2-214	1421	-	ENSP00000484850	272 (aa)	-	A0A087X2B6
ENST00000308511	CCAR2-201	4853	XM_011544603	ENSP00000310670	923 (aa)	XP_011542906	Q8N163

Gene Model

Click here to download ENSG00000158941's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000158941	Eye Movements	8E-6	26242244
ENSG00000158941	Eye Movements	4E-6	26242244

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000158941	rs11778693	8	22605339	?	Exploratory eye movement dysfunction in schizophrenia (cognitive search score)	26242244	[0.74-1.76] unit decrease	1.249	EFO_0007700
ENSG00000158941	rs11778693	8	22605339	?	Exploratory eye movement dysfunction in schizophrenia (responsive search score)	26242244	[1.13-2.77] unit decrease	1.949	EFO_0007700
ENSG00000158941	rs1545837	8	22620294	?	Lung function (FVC)	30595370			EFO_0004312

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000158941's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000158941	CCAR2	80	44.783	ENSG00000060339	CCAR1	73	56.604

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000158941	CCAR2	80	44.397	ENSAPOG00000019427	ccar1	61	57.692	Acanthochromis_polyacanthus
ENSG00000158941	CCAR2	100	98.765	ENSAMEG00000003044	CCAR2	100	92.199	Ailuropoda_melanoleuca
ENSG00000158941	CCAR2	80	44.783	ENSAMEG00000018003	CCAR1	72	39.832	Ailuropoda_melanoleuca
ENSG00000158941	CCAR2	80	43.966	ENSACIG00000021164	ccar1	73	39.248	Amphilophus_citrinellus
ENSG00000158941	CCAR2	80	44.397	ENSAOCG00000004413	ccar1	61	57.692	Amphiprion_ocellaris
ENSG00000158941	CCAR2	80	43.966	ENSAPEG00000013204	ccar1	74	38.333	Amphiprion_percula
ENSG00000158941	CCAR2	80	44.397	ENSATEG00000001698	ccar1	62	57.692	Anabas_testudineus
ENSG00000158941	CCAR2	92	44.970	ENSAPLG00000013870	CCAR1	62	38.994	Anas_platyrhynchos
ENSG00000158941	CCAR2	85	42.570	ENSACAG00000009927	CCAR1	72	39.496	Anolis_carolinensis
ENSG00000158941	CCAR2	99	81.507	ENSACAG00000023505	CCAR2	99	58.768	Anolis_carolinensis
ENSG00000158941	CCAR2	80	44.783	ENSANAG00000023002	CCAR1	73	39.030	Aotus_nancymaae
ENSG00000158941	CCAR2	100	100.000	ENSANAG00000037041	CCAR2	100	97.616	Aotus_nancymaae
ENSG00000158941	CCAR2	80	43.534	ENSACLG00000011175	ccar1	72	38.669	Astatotilapia_calliptera
ENSG00000158941	CCAR2	84	50.350	ENSAMXG00000001383	ccar1	73	38.703	Astyanax_mexicanus
ENSG00000158941	CCAR2	80	49.153	ENSAMXG00000019358	ccar2	97	39.173	Astyanax_mexicanus
ENSG00000158941	CCAR2	99	100.000	ENSBTAG00000005469	CCAR2	100	89.057	Bos_taurus
ENSG00000158941	CCAR2	80	44.783	ENSBTAG00000033457	CCAR1	73	39.832	Bos_taurus
ENSG00000158941	CCAR2	78	32.273	WBGene00003085	ccar-1	52	44.304	Caenorhabditis_elegans
ENSG00000158941	CCAR2	80	44.783	ENSCJAG00000018912	CCAR1	73	39.030	Callithrix_jacchus
ENSG00000158941	CCAR2	100	100.000	ENSCJAG00000020174	CCAR2	100	97.075	Callithrix_jacchus
ENSG00000158941	CCAR2	80	44.783	ENSCAFG00000013761	CCAR1	72	39.832	Canis_familiaris
ENSG00000158941	CCAR2	99	100.000	ENSCAFG00000009285	CCAR2	100	92.958	Canis_familiaris
ENSG00000158941	CCAR2	100	97.531	ENSCAFG00020012923	-	100	97.531	Canis_lupus_dingo
ENSG00000158941	CCAR2	85	43.373	ENSCAFG00020026013	CCAR1	76	39.030	Canis_lupus_dingo
ENSG00000158941	CCAR2	99	100.000	ENSCHIG00000007510	CCAR2	100	88.732	Capra_hircus
ENSG00000158941	CCAR2	80	44.783	ENSCHIG00000000354	CCAR1	73	39.832	Capra_hircus
ENSG00000158941	CCAR2	80	44.783	ENSTSYG00000010684	CCAR1	73	39.832	Carlito_syrichta
ENSG00000158941	CCAR2	99	100.000	ENSTSYG00000001104	CCAR2	100	94.583	Carlito_syrichta
ENSG00000158941	CCAR2	100	97.531	ENSCAPG00000014382	-	100	97.531	Cavia_aperea
ENSG00000158941	CCAR2	80	44.348	ENSCPOG00000004124	CCAR1	72	39.623	Cavia_porcellus
ENSG00000158941	CCAR2	99	100.000	ENSCPOG00000010985	CCAR2	100	93.290	Cavia_porcellus
ENSG00000158941	CCAR2	100	100.000	ENSCCAG00000026081	CCAR2	100	97.400	Cebus_capucinus
ENSG00000158941	CCAR2	80	44.783	ENSCCAG00000020659	CCAR1	73	39.030	Cebus_capucinus
ENSG00000158941	CCAR2	80	44.156	ENSCATG00000042598	CCAR1	73	38.608	Cercocebus_atys
ENSG00000158941	CCAR2	100	100.000	ENSCATG00000031853	CCAR2	100	98.375	Cercocebus_atys
ENSG00000158941	CCAR2	99	100.000	ENSCLAG00000014299	CCAR2	100	92.749	Chinchilla_lanigera
ENSG00000158941	CCAR2	85	42.972	ENSCLAG00000011807	CCAR1	72	39.623	Chinchilla_lanigera
ENSG00000158941	CCAR2	100	100.000	ENSCSAG00000016353	CCAR2	100	98.267	Chlorocebus_sabaeus
ENSG00000158941	CCAR2	80	44.783	ENSCSAG00000007643	CCAR1	72	39.030	Chlorocebus_sabaeus
ENSG00000158941	CCAR2	99	100.000	ENSCHOG00000000997	-	100	85.140	Choloepus_hoffmanni
ENSG00000158941	CCAR2	62	56.122	ENSCHOG00000002868	CCAR1	61	40.399	Choloepus_hoffmanni
ENSG00000158941	CCAR2	99	84.932	ENSCPBG00000002266	CCAR2	99	60.651	Chrysemys_picta_bellii
ENSG00000158941	CCAR2	80	43.478	ENSCPBG00000019635	CCAR1	72	39.076	Chrysemys_picta_bellii
ENSG00000158941	CCAR2	100	100.000	ENSCANG00000003001	CCAR2	100	98.375	Colobus_angolensis_palliatus
ENSG00000158941	CCAR2	65	45.355	ENSCANG00000028727	-	72	39.401	Colobus_angolensis_palliatus
ENSG00000158941	CCAR2	100	98.765	ENSCGRG00001010031	Ccar2	100	90.466	Cricetulus_griseus_chok1gshd
ENSG00000158941	CCAR2	80	44.348	ENSCGRG00001019471	Ccar1	71	39.778	Cricetulus_griseus_chok1gshd
ENSG00000158941	CCAR2	80	44.348	ENSCGRG00000017538	Ccar1	69	39.778	Cricetulus_griseus_crigri
ENSG00000158941	CCAR2	100	98.765	ENSCGRG00000005120	Ccar2	100	90.358	Cricetulus_griseus_crigri
ENSG00000158941	CCAR2	80	43.290	ENSCSEG00000006707	ccar1	73	38.542	Cynoglossus_semilaevis
ENSG00000158941	CCAR2	81	45.106	ENSCVAG00000014095	ccar1	63	58.750	Cyprinodon_variegatus
ENSG00000158941	CCAR2	96	44.056	ENSDARG00000038302	ccar2	94	51.402	Danio_rerio
ENSG00000158941	CCAR2	80	43.913	ENSDARG00000074759	ccar1	73	38.205	Danio_rerio
ENSG00000158941	CCAR2	80	43.478	ENSDNOG00000007499	CCAR1	72	39.203	Dasypus_novemcinctus
ENSG00000158941	CCAR2	99	100.000	ENSDNOG00000019561	CCAR2	100	92.416	Dasypus_novemcinctus
ENSG00000158941	CCAR2	99	98.630	ENSETEG00000013463	CCAR2	100	88.865	Echinops_telfairi
ENSG00000158941	CCAR2	80	41.921	ENSETEG00000013025	CCAR1	68	33.557	Echinops_telfairi
ENSG00000158941	CCAR2	100	99.383	ENSEASG00005018793	CCAR2	100	92.633	Equus_asinus_asinus
ENSG00000158941	CCAR2	88	44.970	ENSEASG00005015474	CCAR1	83	33.261	Equus_asinus_asinus
ENSG00000158941	CCAR2	80	44.783	ENSECAG00000016291	CCAR1	82	34.354	Equus_caballus
ENSG00000158941	CCAR2	100	99.383	ENSECAG00000020651	CCAR2	93	92.308	Equus_caballus
ENSG00000158941	CCAR2	99	99.315	ENSEEUG00000005728	CCAR2	100	87.055	Erinaceus_europaeus
ENSG00000158941	CCAR2	85	42.972	ENSEEUG00000013822	CCAR1	72	36.830	Erinaceus_europaeus
ENSG00000158941	CCAR2	75	44.860	ENSELUG00000004179	ccar2	92	31.690	Esox_lucius
ENSG00000158941	CCAR2	85	42.570	ENSELUG00000022633	ccar1	65	59.211	Esox_lucius
ENSG00000158941	CCAR2	80	44.783	ENSFCAG00000012676	CCAR1	73	39.832	Felis_catus
ENSG00000158941	CCAR2	99	100.000	ENSFCAG00000005666	CCAR2	100	93.283	Felis_catus
ENSG00000158941	CCAR2	80	43.478	ENSFALG00000013015	CCAR1	74	39.076	Ficedula_albicollis
ENSG00000158941	CCAR2	80	44.348	ENSFDAG00000007880	CCAR1	72	39.623	Fukomys_damarensis
ENSG00000158941	CCAR2	100	99.383	ENSFDAG00000017209	CCAR2	100	93.398	Fukomys_damarensis
ENSG00000158941	CCAR2	80	44.397	ENSFHEG00000002061	ccar1	66	58.974	Fundulus_heteroclitus
ENSG00000158941	CCAR2	79	44.934	ENSGMOG00000006757	ccar1	70	39.556	Gadus_morhua
ENSG00000158941	CCAR2	61	52.885	ENSGALG00000004108	-	72	39.604	Gallus_gallus
ENSG00000158941	CCAR2	80	43.966	ENSGAFG00000009459	ccar1	73	40.222	Gambusia_affinis
ENSG00000158941	CCAR2	80	43.966	ENSGACG00000007905	ccar1	70	38.596	Gasterosteus_aculeatus
ENSG00000158941	CCAR2	99	84.932	ENSGAGG00000012143	-	98	60.490	Gopherus_agassizii
ENSG00000158941	CCAR2	85	42.169	ENSGAGG00000022022	CCAR1	72	39.076	Gopherus_agassizii
ENSG00000158941	CCAR2	80	44.783	ENSGGOG00000002776	CCAR1	76	39.030	Gorilla_gorilla
ENSG00000158941	CCAR2	100	100.000	ENSGGOG00000002424	CCAR2	100	99.783	Gorilla_gorilla
ENSG00000158941	CCAR2	80	43.534	ENSHBUG00000022896	ccar1	64	57.692	Haplochromis_burtoni
ENSG00000158941	CCAR2	80	44.348	ENSHGLG00000012835	CCAR1	72	39.623	Heterocephalus_glaber_female
ENSG00000158941	CCAR2	99	100.000	ENSHGLG00000015483	CCAR2	100	93.290	Heterocephalus_glaber_female
ENSG00000158941	CCAR2	99	100.000	ENSHGLG00100005534	CCAR2	100	93.290	Heterocephalus_glaber_male
ENSG00000158941	CCAR2	80	43.913	ENSHGLG00100017513	CCAR1	73	39.413	Heterocephalus_glaber_male
ENSG00000158941	CCAR2	89	50.000	ENSHCOG00000004083	ccar1	71	39.570	Hippocampus_comes
ENSG00000158941	CCAR2	80	43.913	ENSIPUG00000005123	ccar1	62	60.294	Ictalurus_punctatus
ENSG00000158941	CCAR2	80	49.153	ENSIPUG00000006666	ccar2	88	37.653	Ictalurus_punctatus
ENSG00000158941	CCAR2	80	44.783	ENSSTOG00000001539	CCAR1	72	39.706	Ictidomys_tridecemlineatus
ENSG00000158941	CCAR2	99	99.315	ENSSTOG00000011666	CCAR2	100	94.150	Ictidomys_tridecemlineatus
ENSG00000158941	CCAR2	80	43.913	ENSJJAG00000024055	Ccar1	72	39.666	Jaculus_jaculus
ENSG00000158941	CCAR2	80	44.397	ENSKMAG00000004397	ccar1	71	39.300	Kryptolebias_marmoratus
ENSG00000158941	CCAR2	80	43.103	ENSLBEG00000007156	ccar1	63	57.692	Labrus_bergylta
ENSG00000158941	CCAR2	85	42.972	ENSLACG00000015608	CCAR1	68	38.462	Latimeria_chalumnae
ENSG00000158941	CCAR2	100	53.416	ENSLACG00000011333	CCAR2	96	40.264	Latimeria_chalumnae
ENSG00000158941	CCAR2	84	54.745	ENSLOCG00000015653	-	91	36.124	Lepisosteus_oculatus
ENSG00000158941	CCAR2	80	43.723	ENSLOCG00000009307	ccar1	62	65.625	Lepisosteus_oculatus
ENSG00000158941	CCAR2	100	98.667	ENSLAFG00000018459	CCAR2	100	92.416	Loxodonta_africana
ENSG00000158941	CCAR2	92	41.132	ENSLAFG00000006177	CCAR1	95	36.697	Loxodonta_africana
ENSG00000158941	CCAR2	100	100.000	ENSMFAG00000044671	CCAR2	100	98.158	Macaca_fascicularis
ENSG00000158941	CCAR2	80	44.783	ENSMFAG00000035410	CCAR1	75	39.030	Macaca_fascicularis
ENSG00000158941	CCAR2	85	43.373	ENSMMUG00000016652	CCAR1	68	56.604	Macaca_mulatta
ENSG00000158941	CCAR2	100	100.000	ENSMMUG00000021991	CCAR2	100	98.267	Macaca_mulatta
ENSG00000158941	CCAR2	80	44.783	ENSMNEG00000009193	CCAR1	73	39.030	Macaca_nemestrina
ENSG00000158941	CCAR2	100	100.000	ENSMNEG00000031023	CCAR2	100	98.050	Macaca_nemestrina
ENSG00000158941	CCAR2	100	100.000	ENSMLEG00000037244	CCAR2	100	98.267	Mandrillus_leucophaeus
ENSG00000158941	CCAR2	80	44.783	ENSMLEG00000033748	CCAR1	73	39.030	Mandrillus_leucophaeus
ENSG00000158941	CCAR2	85	42.400	ENSMAMG00000000309	ccar1	61	57.692	Mastacembelus_armatus
ENSG00000158941	CCAR2	80	43.534	ENSMZEG00005027683	ccar1	72	38.669	Maylandia_zebra
ENSG00000158941	CCAR2	80	43.043	ENSMGAG00000004166	CCAR1	72	38.994	Meleagris_gallopavo
ENSG00000158941	CCAR2	99	99.315	ENSMAUG00000011127	Ccar2	100	90.141	Mesocricetus_auratus
ENSG00000158941	CCAR2	100	99.383	ENSMICG00000007751	CCAR2	100	94.150	Microcebus_murinus
ENSG00000158941	CCAR2	85	43.373	ENSMICG00000007448	CCAR1	73	35.358	Microcebus_murinus
ENSG00000158941	CCAR2	100	98.765	ENSMOCG00000017002	Ccar2	100	89.816	Microtus_ochrogaster
ENSG00000158941	CCAR2	80	44.348	ENSMOCG00000007793	Ccar1	70	39.778	Microtus_ochrogaster
ENSG00000158941	CCAR2	80	43.103	ENSMMOG00000010483	ccar1	71	39.121	Mola_mola
ENSG00000158941	CCAR2	96	87.821	ENSMODG00000009328	CCAR2	100	72.727	Monodelphis_domestica
ENSG00000158941	CCAR2	85	43.600	ENSMODG00000017358	CCAR1	72	40.042	Monodelphis_domestica
ENSG00000158941	CCAR2	80	43.966	ENSMALG00000018301	ccar1	63	57.692	Monopterus_albus
ENSG00000158941	CCAR2	80	43.913	MGP_CAROLIEiJ_G0015391	Ccar1	70	39.556	Mus_caroli
ENSG00000158941	CCAR2	99	99.315	MGP_CAROLIEiJ_G0019474	Ccar2	100	91.874	Mus_caroli
ENSG00000158941	CCAR2	99	99.315	ENSMUSG00000033712	Ccar2	100	91.441	Mus_musculus
ENSG00000158941	CCAR2	80	43.913	ENSMUSG00000020074	Ccar1	70	39.556	Mus_musculus
ENSG00000158941	CCAR2	100	98.148	MGP_PahariEiJ_G0030491	Ccar2	100	91.008	Mus_pahari
ENSG00000158941	CCAR2	80	43.913	MGP_PahariEiJ_G0030807	Ccar1	70	39.778	Mus_pahari
ENSG00000158941	CCAR2	80	43.913	MGP_SPRETEiJ_G0016202	Ccar1	70	39.556	Mus_spretus
ENSG00000158941	CCAR2	99	99.315	MGP_SPRETEiJ_G0020366	Ccar2	100	91.333	Mus_spretus
ENSG00000158941	CCAR2	99	100.000	ENSMPUG00000003486	CCAR2	98	91.904	Mustela_putorius_furo
ENSG00000158941	CCAR2	80	44.783	ENSMPUG00000004618	CCAR1	72	39.832	Mustela_putorius_furo
ENSG00000158941	CCAR2	100	99.383	ENSMLUG00000005567	CCAR2	100	91.658	Myotis_lucifugus
ENSG00000158941	CCAR2	80	44.783	ENSMLUG00000001270	CCAR1	72	39.832	Myotis_lucifugus
ENSG00000158941	CCAR2	80	44.783	ENSNGAG00000023517	Ccar1	72	38.608	Nannospalax_galili
ENSG00000158941	CCAR2	85	42.400	ENSNBRG00000020668	ccar1	74	38.703	Neolamprologus_brichardi
ENSG00000158941	CCAR2	100	100.000	ENSNLEG00000015683	CCAR2	100	98.592	Nomascus_leucogenys
ENSG00000158941	CCAR2	80	44.783	ENSNLEG00000011679	CCAR1	73	39.030	Nomascus_leucogenys
ENSG00000158941	CCAR2	99	78.896	ENSMEUG00000002163	CCAR2	86	98.230	Notamacropus_eugenii
ENSG00000158941	CCAR2	100	96.296	ENSOPRG00000013271	CCAR2	100	91.008	Ochotona_princeps
ENSG00000158941	CCAR2	69	46.354	ENSOPRG00000016682	CCAR1	51	78.571	Ochotona_princeps
ENSG00000158941	CCAR2	61	53.333	ENSODEG00000005072	-	72	40.099	Octodon_degus
ENSG00000158941	CCAR2	100	91.272	ENSODEG00000008466	CCAR2	100	91.272	Octodon_degus
ENSG00000158941	CCAR2	80	43.534	ENSONIG00000018419	ccar1	64	57.692	Oreochromis_niloticus
ENSG00000158941	CCAR2	99	97.260	ENSOANG00000009829	-	74	84.900	Ornithorhynchus_anatinus
ENSG00000158941	CCAR2	80	44.589	ENSOANG00000015048	-	63	40.535	Ornithorhynchus_anatinus
ENSG00000158941	CCAR2	99	100.000	ENSOCUG00000013228	CCAR2	100	88.299	Oryctolagus_cuniculus
ENSG00000158941	CCAR2	65	45.856	ENSORLG00000007436	ccar1	73	39.547	Oryzias_latipes
ENSG00000158941	CCAR2	80	45.022	ENSORLG00020004040	ccar1	65	57.692	Oryzias_latipes_hni
ENSG00000158941	CCAR2	75	63.934	ENSORLG00015009157	ccar1	65	57.692	Oryzias_latipes_hsok
ENSG00000158941	CCAR2	80	44.589	ENSOMEG00000003998	ccar1	65	57.692	Oryzias_melastigma
ENSG00000158941	CCAR2	99	100.000	ENSOGAG00000010578	CCAR2	100	93.391	Otolemur_garnettii
ENSG00000158941	CCAR2	80	44.783	ENSOGAG00000013294	CCAR1	72	39.832	Otolemur_garnettii
ENSG00000158941	CCAR2	100	96.319	ENSOARG00000010234	CCAR2	100	88.312	Ovis_aries
ENSG00000158941	CCAR2	80	44.783	ENSOARG00000005203	CCAR1	72	39.832	Ovis_aries
ENSG00000158941	CCAR2	100	100.000	ENSPPAG00000041119	CCAR2	100	97.742	Pan_paniscus
ENSG00000158941	CCAR2	80	44.783	ENSPPAG00000035962	CCAR1	72	39.401	Pan_paniscus
ENSG00000158941	CCAR2	99	100.000	ENSPPRG00000013075	CCAR2	100	93.283	Panthera_pardus
ENSG00000158941	CCAR2	80	44.783	ENSPPRG00000022293	CCAR1	73	39.832	Panthera_pardus
ENSG00000158941	CCAR2	80	44.783	ENSPTIG00000009648	CCAR1	73	39.832	Panthera_tigris_altaica
ENSG00000158941	CCAR2	99	100.000	ENSPTIG00000019114	CCAR2	100	93.283	Panthera_tigris_altaica
ENSG00000158941	CCAR2	80	44.783	ENSPTRG00000002560	CCAR1	73	39.030	Pan_troglodytes
ENSG00000158941	CCAR2	100	100.000	ENSPTRG00000020065	CCAR2	100	99.675	Pan_troglodytes
ENSG00000158941	CCAR2	100	100.000	ENSPANG00000018828	CCAR2	100	98.375	Papio_anubis
ENSG00000158941	CCAR2	80	44.783	ENSPANG00000022123	CCAR1	74	39.030	Papio_anubis
ENSG00000158941	CCAR2	72	60.748	ENSPKIG00000018955	ccar2	98	40.984	Paramormyrops_kingsleyae
ENSG00000158941	CCAR2	80	43.043	ENSPKIG00000009310	ccar1	75	37.267	Paramormyrops_kingsleyae
ENSG00000158941	CCAR2	99	84.932	ENSPSIG00000017945	CCAR2	100	60.600	Pelodiscus_sinensis
ENSG00000158941	CCAR2	80	43.723	ENSPSIG00000005136	CCAR1	72	38.866	Pelodiscus_sinensis
ENSG00000158941	CCAR2	89	50.794	ENSPMGG00000010385	ccar1	71	40.265	Periophthalmus_magnuspinnatus
ENSG00000158941	CCAR2	100	98.765	ENSPEMG00000009116	Ccar2	100	92.091	Peromyscus_maniculatus_bairdii
ENSG00000158941	CCAR2	80	43.913	ENSPEMG00000015377	-	70	39.556	Peromyscus_maniculatus_bairdii
ENSG00000158941	CCAR2	86	41.339	ENSPMAG00000001814	ccar1	60	49.057	Petromyzon_marinus
ENSG00000158941	CCAR2	100	98.765	ENSPCIG00000004974	CCAR2	100	82.595	Phascolarctos_cinereus
ENSG00000158941	CCAR2	85	43.600	ENSPCIG00000016044	CCAR1	82	34.015	Phascolarctos_cinereus
ENSG00000158941	CCAR2	80	44.397	ENSPFOG00000003164	ccar1	61	58.974	Poecilia_formosa
ENSG00000158941	CCAR2	80	43.966	ENSPLAG00000000212	ccar1	73	39.167	Poecilia_latipinna
ENSG00000158941	CCAR2	80	44.397	ENSPMEG00000003026	ccar1	62	58.974	Poecilia_mexicana
ENSG00000158941	CCAR2	85	43.200	ENSPREG00000018399	ccar1	72	39.248	Poecilia_reticulata
ENSG00000158941	CCAR2	80	44.783	ENSPPYG00000002392	CCAR1	72	39.030	Pongo_abelii
ENSG00000158941	CCAR2	99	100.000	ENSPPYG00000018426	CCAR2	100	98.267	Pongo_abelii
ENSG00000158941	CCAR2	100	96.000	ENSPCAG00000007376	CCAR2	100	86.688	Procavia_capensis
ENSG00000158941	CCAR2	80	44.783	ENSPCOG00000020489	CCAR1	86	34.114	Propithecus_coquereli
ENSG00000158941	CCAR2	100	99.383	ENSPCOG00000023051	CCAR2	100	94.366	Propithecus_coquereli
ENSG00000158941	CCAR2	99	97.987	ENSPVAG00000006188	CCAR2	100	91.658	Pteropus_vampyrus
ENSG00000158941	CCAR2	80	43.534	ENSPNYG00000007300	ccar1	73	38.669	Pundamilia_nyererei
ENSG00000158941	CCAR2	72	54.206	ENSPNAG00000003917	-	97	36.444	Pygocentrus_nattereri
ENSG00000158941	CCAR2	88	51.220	ENSPNAG00000026936	ccar1	61	61.765	Pygocentrus_nattereri
ENSG00000158941	CCAR2	80	43.913	ENSRNOG00000000397	Ccar1	70	39.556	Rattus_norvegicus
ENSG00000158941	CCAR2	99	99.315	ENSRNOG00000018295	Ccar2	100	91.333	Rattus_norvegicus
ENSG00000158941	CCAR2	100	100.000	ENSRBIG00000028654	CCAR2	100	98.267	Rhinopithecus_bieti
ENSG00000158941	CCAR2	80	44.783	ENSRBIG00000042226	CCAR1	73	39.030	Rhinopithecus_bieti
ENSG00000158941	CCAR2	100	100.000	ENSRROG00000034417	CCAR2	100	98.158	Rhinopithecus_roxellana
ENSG00000158941	CCAR2	80	44.783	ENSRROG00000039231	CCAR1	73	39.030	Rhinopithecus_roxellana
ENSG00000158941	CCAR2	80	44.783	ENSSBOG00000030420	CCAR1	83	33.911	Saimiri_boliviensis_boliviensis
ENSG00000158941	CCAR2	100	100.000	ENSSBOG00000033571	CCAR2	100	97.183	Saimiri_boliviensis_boliviensis
ENSG00000158941	CCAR2	99	97.945	ENSSHAG00000018601	CCAR2	99	82.538	Sarcophilus_harrisii
ENSG00000158941	CCAR2	85	43.600	ENSSHAG00000007504	CCAR1	72	40.042	Sarcophilus_harrisii
ENSG00000158941	CCAR2	85	42.570	ENSSFOG00015002717	ccar1	71	39.348	Scleropages_formosus
ENSG00000158941	CCAR2	85	43.200	ENSSMAG00000002119	ccar1	61	57.692	Scophthalmus_maximus
ENSG00000158941	CCAR2	80	43.966	ENSSDUG00000009187	ccar1	61	57.692	Seriola_dumerili
ENSG00000158941	CCAR2	80	42.979	ENSSLDG00000019960	ccar1	72	38.557	Seriola_lalandi_dorsalis
ENSG00000158941	CCAR2	98	100.000	ENSSARG00000003864	CCAR2	100	83.477	Sorex_araneus
ENSG00000158941	CCAR2	80	44.783	ENSSARG00000002783	CCAR1	70	39.662	Sorex_araneus
ENSG00000158941	CCAR2	99	82.192	ENSSPUG00000012349	CCAR2	100	60.673	Sphenodon_punctatus
ENSG00000158941	CCAR2	85	41.767	ENSSPUG00000001288	-	80	39.076	Sphenodon_punctatus
ENSG00000158941	CCAR2	80	43.966	ENSSPAG00000021364	ccar1	61	57.692	Stegastes_partitus
ENSG00000158941	CCAR2	99	100.000	ENSSSCG00000009628	CCAR2	100	92.308	Sus_scrofa
ENSG00000158941	CCAR2	80	44.783	ENSSSCG00000010243	CCAR1	73	39.832	Sus_scrofa
ENSG00000158941	CCAR2	65	44.199	ENSTGUG00000013957	-	100	36.898	Taeniopygia_guttata
ENSG00000158941	CCAR2	80	43.478	ENSTGUG00000003765	-	70	39.778	Taeniopygia_guttata
ENSG00000158941	CCAR2	85	43.200	ENSTRUG00000013280	ccar1	64	57.692	Takifugu_rubripes
ENSG00000158941	CCAR2	85	43.200	ENSTNIG00000008667	ccar1	72	38.866	Tetraodon_nigroviridis
ENSG00000158941	CCAR2	100	98.765	ENSTBEG00000010135	CCAR2	92	98.718	Tupaia_belangeri
ENSG00000158941	CCAR2	80	42.308	ENSTTRG00000001567	CCAR1	69	38.669	Tursiops_truncatus
ENSG00000158941	CCAR2	97	99.306	ENSTTRG00000012752	CCAR2	100	80.715	Tursiops_truncatus
ENSG00000158941	CCAR2	85	43.373	ENSUAMG00000016493	CCAR1	72	40.347	Ursus_americanus
ENSG00000158941	CCAR2	99	100.000	ENSUAMG00000024919	CCAR2	100	92.416	Ursus_americanus
ENSG00000158941	CCAR2	85	43.373	ENSUMAG00000007561	CCAR1	72	40.347	Ursus_maritimus
ENSG00000158941	CCAR2	99	100.000	ENSUMAG00000004780	CCAR2	100	92.091	Ursus_maritimus
ENSG00000158941	CCAR2	99	100.000	ENSVVUG00000005152	CCAR2	100	92.958	Vulpes_vulpes
ENSG00000158941	CCAR2	80	44.783	ENSVVUG00000020327	CCAR1	74	39.832	Vulpes_vulpes
ENSG00000158941	CCAR2	80	43.590	ENSXETG00000008844	ccar1	75	39.331	Xenopus_tropicalis
ENSG00000158941	CCAR2	80	43.966	ENSXCOG00000012603	ccar1	72	38.831	Xiphophorus_couchianus
ENSG00000158941	CCAR2	80	44.397	ENSXMAG00000002765	ccar1	61	58.974	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000790	nuclear chromatin	23352644.	IDA	Component
GO:0000993	RNA polymerase II complex binding	21873635.	IBA	Function
GO:0000993	RNA polymerase II complex binding	22446626.	IDA	Function
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0004857	enzyme inhibitor activity	18235501.18235502.	IDA	Function
GO:0004857	enzyme inhibitor activity	19218236.	IMP	Function
GO:0005515	protein binding	17314511.18235501.18235502.20074560.20160719.21030595.22190034.22446626.23398316.24824780.25661920.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	15824730.20074560.20160719.24824780.25661920.	IDA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005737	cytoplasm	15824730.20160719.24824780.	IDA	Component
GO:0005759	mitochondrial matrix	15824730.	IDA	Component
GO:0006355	regulation of transcription, DNA-templated	21873635.	IBA	Process
GO:0006397	mRNA processing	-	IEA	Process
GO:0006974	cellular response to DNA damage stimulus	-	IEA	Process
GO:0007049	cell cycle	-	IEA	Process
GO:0008380	RNA splicing	21873635.	IBA	Process
GO:0008380	RNA splicing	22446626.	IMP	Process
GO:0009411	response to UV	23352644.	IMP	Process
GO:0016055	Wnt signaling pathway	-	IEA	Process
GO:0019899	enzyme binding	18235501.19218236.23382074.	IPI	Function
GO:0030308	negative regulation of cell growth	25661920.	IMP	Process
GO:0030374	nuclear receptor transcription coactivator activity	21873635.	IBA	Function
GO:0031647	regulation of protein stability	23398316.	IDA	Process
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	23398316.	IDA	Process
GO:0032784	regulation of DNA-templated transcription, elongation	22446626.	IMP	Process
GO:0042752	regulation of circadian rhythm	-	ISS	Process
GO:0043065	positive regulation of apoptotic process	18235501.18235502.	IMP	Process
GO:0043086	negative regulation of catalytic activity	21030595.	IMP	Process
GO:0043653	mitochondrial fragmentation involved in apoptotic process	15824730.	IDA	Process
GO:0044609	DBIRD complex	21873635.	IBA	Component
GO:0044609	DBIRD complex	22446626.	IDA	Component
GO:0045892	negative regulation of transcription, DNA-templated	20160719.	IDA	Process
GO:0045892	negative regulation of transcription, DNA-templated	20074560.25661920.	IMP	Process
GO:0048511	rhythmic process	-	IEA	Process
GO:0090263	positive regulation of canonical Wnt signaling pathway	24824780.	IMP	Process
GO:0090311	regulation of protein deacetylation	21030595.	IDA	Process
GO:1900034	regulation of cellular response to heat	-	TAS	Process
GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	23352644.	IMP	Process
GO:1903508	positive regulation of nucleic acid-templated transcription	-	IEA	Process
GO:2000003	positive regulation of DNA damage checkpoint	23352644.	IMP	Process

EuRBPDB

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

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GWAS

PPI

Paralogs

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Gene Ontology

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Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.