Cancer | Chr | Position | Mutation Type | dbSNP | Protein-change | Allele Freq | RBD |
---|---|---|---|---|---|---|---|
BLCA | |||||||
CESC | |||||||
COAD | |||||||
LGG | |||||||
LUAD | |||||||
READ | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC |
Cancer | Type | Freq | Q-value |
---|---|---|---|
OV | |||
THYM |
Cancer | P-value | Q-value |
---|---|---|
KIRC | ||
STAD | ||
SARC | ||
MESO | ||
ACC | ||
SKCM | ||
UCEC | ||
LIHC | ||
LGG | ||
THCA | ||
UVM | ||
OV |
Transcript ID | Name | Length | RefSeq ID | Protein ID | Length | RefSeq ID | UniportKB ID |
---|---|---|---|---|---|---|---|
ENST00000462349 | CBS-210 | 1038 | - | - | - (aa) | - | - |
ENST00000486098 | CBS-214 | 773 | - | - | - (aa) | - | - |
ENST00000451248 | CBS-207 | 573 | - | ENSP00000402823 | 149 (aa) | - | H7C1W6 |
ENST00000478709 | CBS-213 | 727 | - | - | - (aa) | - | - |
ENST00000461686 | CBS-209 | 2656 | - | - | - (aa) | - | - |
ENST00000398165 | CBS-204 | 2605 | XM_024452136 | ENSP00000381231 | 551 (aa) | XP_024307904 | P35520 |
ENST00000458223 | CBS-208 | 676 | - | ENSP00000408014 | 159 (aa) | - | H7C2W0 |
ENST00000470912 | CBS-212 | 894 | - | - | - (aa) | - | - |
ENST00000430013 | CBS-205 | 828 | - | ENSP00000405929 | 224 (aa) | - | H7C2H4 |
ENST00000491776 | CBS-216 | 1515 | - | - | - (aa) | - | - |
ENST00000488526 | CBS-215 | 672 | - | - | - (aa) | - | - |
ENST00000352178 | CBS-201 | 2583 | XM_024452138 | ENSP00000344460 | 551 (aa) | XP_024307906 | P35520 |
ENST00000465732 | CBS-211 | 683 | - | - | - (aa) | - | - |
ENST00000359624 | CBS-202 | 2353 | XM_011529774 | ENSP00000352643 | 551 (aa) | XP_011528076 | P35520 |
ENST00000496485 | CBS-217 | 673 | - | - | - (aa) | - | - |
ENST00000398158 | CBS-203 | 2453 | XM_011529777 | ENSP00000381225 | 551 (aa) | XP_011528079 | P35520 |
ENST00000441030 | CBS-206 | 819 | - | ENSP00000388235 | 177 (aa) | - | C9JMA6 |
ensgID | Trait | pValue | Pubmed ID |
---|---|---|---|
ENSG00000160200 | Nutritional and Metabolic Diseases | 2.1730000E-006 | - |
ENSG00000160200 | Child Development Disorders, Pervasive | 3.4000000E-005 | - |
ENSG00000160200 | Selenium | 5E-6 | 23720494 |
ENSG00000160200 | Homocysteine | 3E-26 | 24651765 |
ENSG00000160200 | Homocysteine | 4E-6 | 23251661 |
ENSG00000160200 | Homocysteine | 3E-10 | 20031578 |
ENSG00000160200 | Homocysteine | 4E-24 | 23824729 |
ENSG00000160200 | Selenium | 5E-9 | 25343990 |
ENSG00000160200 | Selenium | 4E-9 | 25343990 |
ENSG00000160200 | Homocysteine | 2E-12 | 23824729 |
ENSG00000160200 | Metabolism | 1E-11 | 24816252 |
ENSG00000160200 | Selenium | 3E-8 | 25343990 |
ensgID | SNP | Chromosome | Position | SNP-risk | Trait | PubmedID | 95% CI | Or or BEAT | EFO ID |
---|---|---|---|---|---|---|---|---|---|
ENSG00000160200 | rs6586282 | 21 | 43058387 | T | Blood and toenail selenium levels | 25343990 | EFO_0006331 | ||
ENSG00000160200 | rs1789953 | 21 | 43062826 | T | Blood and toenail selenium levels | 25343990 | EFO_0006331 | ||
ENSG00000160200 | rs234709 | 21 | 43066854 | T | Blood and toenail selenium levels | 25343990 | EFO_0006331 | ||
ENSG00000160200 | rs6586282 | 21 | 43058387 | ? | Blood trace element (Se levels) | 23720494 | [0.068-0.166] unit increase | 0.117 | EFO_0005266 |
ENSG00000160200 | rs234709 | 21 | 43066854 | T | Homocysteine levels | 23824729 | [0.058-0.086] unit decrease | 0.0718 | EFO_0004578 |
ENSG00000160200 | rs2851391 | 21 | 43067294 | T | Homocysteine levels | 23824729 | [0.04-0.072] unit increase | 0.056 | EFO_0004578 |
ENSG00000160200 | rs234714 | 21 | 43067923 | T | Plasma homocysteine levels (post-methionine load test) | 24651765 | [0.31-0.49] unit increase | 0.404 | EFO_0004578 |
ENSG00000160200 | rs6586282 | 21 | 43058387 | ? | Homocysteine levels | 20031578 | [NR] unit decrease | 0.03 | EFO_0004578 |
ENSG00000160200 | rs2851391 | 21 | 43067294 | T | Blood metabolite levels | 24816252 | [0.0081-0.0159] unit decrease | 0.012 | EFO_0005664 |
ENSG00000160200 | rs2851391 | 21 | 43067294 | G | Obesity-related traits | 23251661 | [NR] µmol/L increase | 0.02 | EFO_0004578 |
Ensembl ID | Gene Symbol | Coverage | Identiy | Ortholog | Gene Symbol | Coverage | Identiy | Species |
---|---|---|---|---|---|---|---|---|
ENSG00000160200 | CBS | 75 | 46.667 | YGR155W | CYS4 | 85 | 46.667 | Saccharomyces_cerevisiae |
Go ID | Go_term | PubmedID | Evidence | Category |
---|---|---|---|---|
GO:0004122 | cystathionine beta-synthase activity | 7929220.18776696.19010420.22985361.23981774.24416422. | IDA | Function |
GO:0004124 | cysteine synthase activity | 21873635. | IBA | Function |
GO:0005515 | protein binding | 17087506.25416956. | IPI | Function |
GO:0005634 | nucleus | 17087506. | IDA | Component |
GO:0005737 | cytoplasm | 21873635. | IBA | Component |
GO:0005737 | cytoplasm | 23981774. | IDA | Component |
GO:0005829 | cytosol | 16780588. | HDA | Component |
GO:0005829 | cytosol | - | TAS | Component |
GO:0006535 | cysteine biosynthetic process from serine | 21873635. | IBA | Process |
GO:0006563 | L-serine metabolic process | 19010420. | IDA | Process |
GO:0006565 | L-serine catabolic process | 18776696. | IDA | Process |
GO:0019343 | cysteine biosynthetic process via cystathionine | - | IEA | Process |
GO:0019344 | cysteine biosynthetic process | 24416422. | IDA | Process |
GO:0019346 | transsulfuration | 21873635. | IBA | Process |
GO:0019346 | transsulfuration | - | TAS | Process |
GO:0019448 | L-cysteine catabolic process | 15520012. | IDA | Process |
GO:0019825 | oxygen binding | 24515102. | IDA | Function |
GO:0019899 | enzyme binding | 17087506. | IPI | Function |
GO:0020037 | heme binding | 21873635. | IBA | Function |
GO:0020037 | heme binding | 7929220.24515102. | IDA | Function |
GO:0020037 | heme binding | 18776696. | IMP | Function |
GO:0030170 | pyridoxal phosphate binding | 21873635. | IBA | Function |
GO:0030170 | pyridoxal phosphate binding | 7929220.18776696. | IDA | Function |
GO:0031625 | ubiquitin protein ligase binding | 17087506. | IPI | Function |
GO:0042262 | DNA protection | 24534463. | IMP | Process |
GO:0042802 | identical protein binding | 16189514.19447967.21900206.25416956. | IPI | Function |
GO:0042803 | protein homodimerization activity | 11483494. | IDA | Function |
GO:0043418 | homocysteine catabolic process | 18776696.24416422. | IDA | Process |
GO:0046872 | metal ion binding | - | IEA | Function |
GO:0050421 | nitrite reductase (NO-forming) activity | 24416422. | IDA | Function |
GO:0050667 | homocysteine metabolic process | 21873635. | IBA | Process |
GO:0050667 | homocysteine metabolic process | 19010420.20031578.23981774. | IDA | Process |
GO:0055114 | oxidation-reduction process | - | IEA | Process |
GO:0070025 | carbon monoxide binding | 24515102. | IDA | Function |
GO:0070026 | nitric oxide binding | 24416422.24515102. | IDA | Function |
GO:0070814 | hydrogen sulfide biosynthetic process | 21873635. | IBA | Process |
GO:0070814 | hydrogen sulfide biosynthetic process | 15520012.24416422. | IDA | Process |
GO:0070814 | hydrogen sulfide biosynthetic process | - | ISS | Process |
GO:0072341 | modified amino acid binding | 20031578. | IDA | Function |
GO:1904047 | S-adenosyl-L-methionine binding | 22985361. | IDA | Function |