EuRBPDB

  • Home
  • Cancer
  • Family
  • Species
  • RBPredictor
  • Search
  • Download
  • Submit
  • Help
  • Contact
TCGA tumor abbreviations
  • ACCAdrenocortical carcinoma
  • BLCABladder Urothelial Carcinoma
  • BRCABreast invasive carcinoma
  • CESCCervical squamous cell carcinoma and endocervical adenocarcinoma
  • CHOLCholangio carcinoma
  • COADColon adenocarcinoma
  • DLBCLymphoid Neoplasm Diffuse Large B-cell Lymphoma
  • ESCAEsophageal carcinoma
  • GBMGlioblastoma multiforme
  • HNSCHead and Neck squamous cell carcinoma
  • KICHKidney Chromophobe
  • KIRCKidney renal clear cell carcinoma
  • KIRPKidney renal papillary cell carcinoma
  • LAMLAcute Myeloid Leukemia
  • LGGBrain Lower Grade Glioma
  • LIHCLiver hepatocellular carcinoma
  • LUADLung adenocarcinoma
  • LUSCLung squamous cell carcinoma
  • MESOMesothelioma
  • OVOvarian serous cystadenocarcinoma
  • PAADPancreatic adenocarcinoma
  • PCPGPheochromocytoma and Paraganglioma
  • PRADProstate adenocarcinoma
  • READRectum adenocarcinoma
  • SARCSarcoma
  • SKCMSkin Cutaneous Melanoma
  • STADStomach adenocarcinoma
  • TGCTThyroid carcinoma
  • THCAThyroid carcinoma
  • THYMThymoma
  • UCECUterine Corpus Endometrial Carcinoma
  • UCSUterine Carcinosarcoma
  • UVMUveal Melanoma

Note: Click here to get the extension of tumor abbreviations.


  • Cancer Related Information
  • Basic Information

Cancer associated literatures
PIDTitleArticle TimeAuthorDoi
28919351Suspension state increases reattachment of breast cancer cells by up-regulating lamin A/C.Biochim Biophys Acta Mol Cell Res2017 DecZhang Xdoi: 10.1016/j.bbamcr.2017.09.006
30190500Nuclear Nestin deficiency drives tumor senescence via lamin A/C-dependent nuclear deformation.Nat Commun2018 Sep 6Zhang Ydoi: 10.1038/s41467-018-05808-y.
23049808LMNA knock-down affects differentiation and progression of human neuroblastoma cells.PLoS One2012Maresca Gdoi: 10.1371/journal.pone.0045513
26439802Down-regulation of the Lamin A/C in neuroblastoma triggers the expansion of tumor initiating cells.Oncotarget2015 Oct 20Nardella Mdoi: 10.18632/oncotarget.5104.
26447202Lamin A/C deficiency reduces circulating tumor cell resistance to fluid shear stress.Am J Physiol Cell Physiol2015 Dec 1Mitchell MJdoi: 10.1152/ajpcell.00050.2015
21627864Loss of A-type lamin expression compromises nuclear envelope integrity in breast cancer.Chin J Cancer2011 JunCapo-chichi CD-
29378184miR-218 and miR-129 regulate breast cancer progression by targeting Lamins.Biochem Biophys Res Commun2018 Feb 12Setijono SRdoi: 10.1016/j.bbrc.2018.01.146
21439080Nuclear envelope structural defects cause chromosomal numerical instability and aneuploidy in ovarian cancer.BMC Med2011 Mar 26Capo-chichi CDdoi: 10.1186/1741-7015-9-28.
22057372Methylation status of lamin A/C in gastric cancer cell lines.Hepatogastroenterology2012 JunLee WSdoi: 10.5754/hge11610.
26732077Altered Lamin A/C splice variant expression as a possible diagnostic marker in breast cancer.Cell Oncol (Dordr)2016 AprAljada Adoi: 10.1007/s13402-015-0265-1
25499720Loss of lamin A but not lamin C expression in epithelial ovarian cancer cells is associated with metastasis and poor prognosis.Pathol Res Pract2015 FebGong Gdoi: 10.1016/j.prp.2014.11.008
21621406Loss of lamin A/C expression in stage II and III colon cancer is associated with disease recurrence.Eur J Cancer2011 AugBelt EJdoi: 10.1016/j.ejca.2011.04.025
26537870Lamin A/C deficiency is an independent risk factor for cervical cancer.Cell Oncol (Dordr)2016 FebCapo-chichi CDdoi: 10.1007/s13402-015-0252-6
24293108The clinicopathological significance of lamin A/C, lamin B1 and lamin B receptor mRNA expression in human breast cancer.Cell Mol Biol Lett2013 DecWazir Udoi: 10.2478/s11658-013-0109-9
29665450Lamin A/C might be involved in the EMT signalling pathway.Gene2018 Jul 15Zuo Ldoi: 10.1016/j.gene.2018.04.040

Differential Expression

Expression in 33 cancers

Mutations
CancerChrPosition Mutation TypedbSNPProtein-change Allele FreqRBD
BLCAchr1156135918Silentrs397517914A318A0.31
BLCAchr1156126760Intronnovel0.67
BLCAchr1156138655SilentnovelV622V0.27
BLCAchr1156139079Splice_SitenovelX657_splice0.08
BLCAchr1156130666Missense_MutationNAD136N0.69
BLCAchr1156136218Missense_Mutationrs58133342R388C0.13
BLCAchr1156136889Intronnovel0.33
BLCAchr1156115032SilentnovelL38L0.55
BLCAchr1156130693Frame_Shift_DelnovelE145Mfs*140.26
BLCAchr1156130716SilentNAL152L0.44
BLCAchr1156115261Missense_MutationnovelE115K0.31
BLCAchr11561391303'UTRrs7454211990.23
BLCAchr11561391313'UTRnovel0.24
BLCAchr1156115090Missense_MutationnovelG58R0.5
BLCAchr1156126860Intronnovel0.45
BRCAchr1156136858Intronnovel0.12
BRCAchr1156134458Missense_Mutationrs267607571R190Q0.21
BRCAchr1156137705Missense_MutationnovelE554K0.06
BRCAchr1156115168Missense_Mutationrs794728602E84K0.22
CESCchr11561393603'UTRnovel0.27
CESCchr1156126911Intronnovel0.15
CESCchr1156115256Frame_Shift_DelnovelF113Wfs*30.12
CESCchr1156135865IntronNA0.4
CESCchr1156135244Missense_Mutationrs397517912E290K0.21
COADchr1156135950Missense_Mutationrs397517913R329H0.41
COADchr11561148325'UTRnovel0.43
COADchr1156138314Intronnovel0.44
COADchr11561392433'UTRnovel0.5
COADchr1156136379SilentnovelA441A0.48
COADchr1156115072Missense_Mutationrs397517895L52V0.08
COADchr1156137830Intronnovel0.22
COADchr1156136352SilentnovelQ432Q0.09
COADchr11561391313'UTRnovel0.29
COADchr1156130726Missense_Mutationrs760743233R156C0.19
COADchr11561391653'UTRnovel0.18
DLBCchr1156136873Intronnovel0.38
DLBCchr1156137751Splice_Regionnovel0.21
ESCAchr1156137842Intronnovel0.21
ESCAchr1156115010In_Frame_DelnovelK32del0.14
ESCAchr1156136414Missense_Mutationrs267607598R453Q0.06
GBMchr1156135163Intronnovel0.26
GBMchr11561391693'UTRnovel0.11
GBMchr1156115030Missense_MutationnovelL38F0.56
HNSCchr1156137107Splice_Regionnovel0.26
HNSCchr1156130634Missense_MutationnovelG125A0.11
HNSCchr1156136956SilentnovelQ472Q0.56
KIRCchr1156138602Missense_MutationnovelA605T0.23
KIRPchr1156115052Missense_Mutationrs58436778Y45C0.29
KIRPchr1156135313Splice_SitenovelX312_splice0.21
KIRPchr1156137683SilentNAS546S0.39
KIRPchr1156138424Intronnovel0.42
KIRPchr1156135294SilentNAL306L0.35
LGGchr1156136116SilentnovelE384E0.27
LGGchr1156134893Missense_MutationNAD243G0.22
LGGchr1156135196Missense_MutationnovelA274T0.09
LIHCchr1156136370SilentnovelG438G0.23
LIHCchr1156130615Splice_SiteNAX119_splice0.29
LIHCchr1156138694SilentNAG635G0.21
LIHCchr1156136391SilentnovelV445V0.53
LIHCchr1156136392Missense_MutationnovelD446N0.53
LUADchr1156130632SilentNAE124E0.31
LUADchr1156137144Frame_Shift_InsnovelT510Yfs*420.54
LUADchr1156114954SilentNAS12S0.59
LUADchr1156134963SilentnovelT266T0.05
LUADchr1156126815Intronnovel0.39
LUADchr1156136091Missense_MutationNAY376C0.27
LUADchr1156136892Intronnovel0.19
LUADchr1156135180Splice_Regionnovel0.11
LUSCchr1156130643Missense_MutationnovelI128K0.09
LUSCchr1156135151Intronnovel0.18
LUSCchr1156136993Missense_MutationnovelP485T0.35
LUSCchr1156130720Missense_MutationnovelE154K0.26
LUSCchr1156115134SilentNAR72R0.52
LUSCchr1156138712SilentnovelL641L0.16
OVchr1156126897Intronrs7603181580.21
OVchr11561391943'UTRnovel0.13
OVchr1156134932Missense_MutationNAV256G0.13
OVchr1156126807Intronnovel0.09
OVchr1156134517Missense_MutationNAI210V0.07
OVchr1156138529Missense_MutationNAN580K0.42
PAADchr1156136017SilentnovelR351R0.05
PAADchr1156126615Intronnovel0.23
PCPGchr1156136320Nonsense_MutationnovelE422*0.27
PRADchr1156135949Missense_MutationNAR329C0.2
PRADchr1156134427Frame_Shift_DelnovelK180Rfs*210.3
PRADchr1156130727Missense_Mutationrs764475194R156H0.53
PRADchr1156136378Missense_MutationnovelA441V0.5
PRADchr11561391153'UTRnovel0.33
READchr1156134857Missense_Mutationrs760388350N231S0.41
READchr1156137027Missense_Mutationrs200466188T496M0.29
READchr1156138593Missense_Mutationrs60662302G602S0.39
READchr1156135885Intronnovel0.17
SARCchr1156137768Intronrs7275044350.19
SKCMchr1156134853Missense_MutationNAD230Y0.14
SKCMchr1156135148Intronnovel0.2
SKCMchr1156136077Missense_MutationnovelM371I0.19
SKCMchr1156115123Missense_MutationNAV69M0.68
SKCMchr1156136265Silentrs776975256S403S0.54
SKCMchr1156136001Missense_MutationnovelA346V0.09
SKCMchr1156136002SilentnovelA346A0.09
SKCMchr1156137158SilentnovelL512L0.25
SKCMchr1156115230SilentNAL104L0.22
SKCMchr1156135948SilentNAA328A0.12
SKCMchr1156138493SilentnovelS568S0.28
SKCMchr1156114998Missense_MutationNAT27I0.05
SKCMchr1156130614Splice_Regionnovel0.17
SKCMchr11561392523'UTRnovel0.5
SKCMchr1156138688SilentnovelG633G0.29
SKCMchr1156136013Missense_MutationNAA350V0.38
SKCMchr1156136904Intronnovel0.15
SKCMchr1156135282SilentNAL302L0.47
SKCMchr1156115122Silentrs753304214E68E0.16
STADchr1156137030Splice_SiteNAX496_splice0.12
STADchr1156138675Frame_Shift_Insrs770335541S632Qfs*720.19
STADchr1156135234SilentNAG286G0.08
STADchr1156137095Intronnovel0.14
STADchr1156138660Missense_Mutationrs13768R624H0.43
STADchr1156134936SilentnovelE257E0.11
STADchr1156136224Frame_Shift_InsnovelS392Qfs*340.29
STADchr1156135890Intronnovel0.11
STADchr1156130636Missense_MutationnovelD126N0.29
STADchr1156138537Missense_Mutationrs59601651S583L0.34
STADchr1156138659In_Frame_DelnovelY626_S628del0.58
STADchr1156136952Missense_Mutationrs267607578R471H0.14
STADchr1156138680Missense_MutationNAG631S0.32
STADchr1156135263Missense_MutationNAR296H0.31
STADchr1156136252Missense_Mutationrs267607563R399H0.42
THCAchr1156136458Intronnovel0.22
THYMchr1156135925Frame_Shift_InsnovelL327Rfs*1620.06
UCECchr1156139085SilentnovelP658P0.22
UCECchr1156136240Missense_Mutationrs267607561S395L0.34
UCECchr1156137849Intronnovel0.29
UCECchr1156137068Intronnovel0.2
UCECchr1156138675Frame_Shift_Insrs770335541S632Qfs*720.18
UCECchr11561392343'UTRnovel0.46
UCECchr1156135991Missense_Mutationrs749784223R343W0.34
UCECchr1156136336Missense_Mutationrs747139279R427H0.28
UCECchr1156135955Missense_MutationNAR331W0.32
UCECchr1156134827Missense_Mutationrs372567202R221H0.25
UCECchr1156136257Missense_Mutationrs61094188R401C0.23
UCECchr1156134891Silentrs763625309A242A0.5
UCECchr1156139090Missense_MutationnovelN660S0.12
UCECchr1156137125Nonsense_MutationnovelG501*0.08
UCECchr11561392433'UTRnovel0.51
UCECchr1156134811Missense_Mutationrs794728591R216C0.2
UCECchr1156136294Missense_MutationnovelG413D0.3
UCECchr1156130697Missense_MutationnovelA146V0.17
UCECchr1156134824Missense_Mutationrs780066296R220H0.41
UCECchr1156135926Missense_MutationnovelR321Q0.21
UCECchr1156137203Missense_Mutationrs57318642R527C0.45
UCECchr1156115183Missense_MutationNAR89S0.21
UCECchr1156129872Intronnovel0.13
UCECchr11561392273'UTRnovel0.33
UCECchr11561392433'UTRnovel0.18
UCECchr1156136700Intronnovel0.78
UCECchr1156137097Intronnovel0.41
UCECchr11561392113'UTRnovel0.35
UCECchr1156135263Missense_MutationNAR296H0.47
UCECchr1156136413Missense_Mutationrs58932704R453W0.23
UCECchr11561392433'UTRnovel0.4
UCECchr11561391843'UTRnovel0.48
UCECchr1156135166Intronnovel0.13
UCECchr1156135286Missense_MutationnovelA304T0.32
UCECchr1156134519SilentnovelI210I0.59
UCECchr1156134869Missense_Mutationrs759829161R235H0.34
UCECchr1156135821Intronnovel0.42
UCECchr1156136090Missense_MutationnovelY376H0.35
UCECchr1156136928Missense_Mutationrs778099589S463F0.46
UCECchr11561392273'UTRnovel0.46

Copy Number Variations (CNVs)
CancerTypeFreq Q-value
DLBCDEL0.02080.0017831
ESCAAMP0.39670.0022446
KIRCAMP0.09280.059566
LGGAMP0.06820.029503
PAADAMP0.22830.085665
READAMP0.26670.025154
SKCMAMP0.48779.6912e-06
TGCTAMP0.340.088103
UCECAMP0.4491.3482e-23

Survival Analysis
CancerP-value Q-value
MESO0.00011

Kaplan-Meier Survival Analysis

ACC0.0049

Kaplan-Meier Survival Analysis

UCS0.05

Kaplan-Meier Survival Analysis

COAD0.048

Kaplan-Meier Survival Analysis

PAAD0.02

Kaplan-Meier Survival Analysis

BLCA0.021

Kaplan-Meier Survival Analysis

READ0.015

Kaplan-Meier Survival Analysis

LAML0.00013

Kaplan-Meier Survival Analysis

GBM0.011

Kaplan-Meier Survival Analysis

LIHC0.0082

Kaplan-Meier Survival Analysis

LUAD0.027

Kaplan-Meier Survival Analysis

UVM0.0079

Kaplan-Meier Survival Analysis

Drugs

Select Dataset :


Input Drug :


Input Cell Line :


Eesembl ID



Cell lines and drugs in GSE70138 or GSE92742

  • Description
  • RBPome
  • Literatures
  • Expression
  • Transcripts
  • Gene Model
  • Pathways
  • Phenotypes
  • GWAS
  • PPI
  • Orthologs
  • Gene Ontology
Description
Ensembl ID
ENSG00000160789 (Gene tree)
Gene ID
4000
Gene Symbol
LMNA
Alias
HGPS|MADA|LMN1|CMD1A|LGMD1B|PRO1|LMNL1
Full Name
lamin A/C
Gene Type
protein_coding
Species
Homo_sapiens
Status
confidence
Strand
Plus strand
Length
57,544 bases
Position
chr1:156,082,546-156,140,089
Accession
6636
RBP type
non-canonical RBP
Summary
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq, Apr 2012]
RNA binding proteome (RBPome)
PIDTitleMethod TimeAuthorDoi
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & HEK2932019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & HEK2932018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
29431736Capturing the interactome of newly transcribed RNAPolyT-RICK & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
29431736Capturing the interactome of newly transcribed RNARIC & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
29431736Capturing the interactome of newly transcribed RNARICK & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & Hela2018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & MCF10A2019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & MCF72018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & U2OS2019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
27453046Comprehensive Identification of RNA-Binding Domains in Human CellsRIC & Hela2016 Aug 18Castello ADOI: 10.1016/j.molcel.2016.06.029

Literatures on RNA binding capacity
PIDTitleArticle TimeAuthorDoi
31317183Dilated cardiomyopathy and arrhythmogenic left ventricular cardiomyopathy: a comprehensive genotype-imaging phenotype study.Eur Heart J Cardiovasc Imaging2019 Jul 16Augusto JBdoi: 10.1093/ehjci/jez188
Expression
Transcripts
Transcript IDNameLengthRefSeq ID Protein IDLengthRefSeq IDUniportKB ID
ENST00000508500LMNA-222848-ENSP00000424977260 (aa)-A0A0C4DGC5
ENST00000498722LMNA-2171348--- (aa)--
ENST00000515824LMNA-225393--- (aa)--
ENST00000504687LMNA-220546-ENSP00000426535182 (aa)-H0YAB0
ENST00000502751LMNA-219570--- (aa)--
ENST00000469565LMNA-210591--- (aa)--
ENST00000515711LMNA-224569--- (aa)--
ENST00000470835LMNA-212472--- (aa)--
ENST00000515459LMNA-223757-ENSP0000042451838 (aa)-D6RB20
ENST00000506981LMNA-221576--- (aa)--
ENST00000473598LMNA-2132015-ENSP00000421821565 (aa)-P02545
ENST00000368301LMNA-2072461-ENSP00000357284572 (aa)-P02545
ENST00000368300LMNA-2063190XM_011509534ENSP00000357283664 (aa)XP_011507836P02545
ENST00000361308LMNA-2021713-ENSP00000355292487 (aa)-Q3BDU5
ENST00000478063LMNA-214285--- (aa)--
ENST00000347559LMNA-2013137-ENSP00000292304634 (aa)-P02545
ENST00000448611LMNA-2081943XM_011509533ENSP00000395597574 (aa)XP_011507835P02545
ENST00000459904LMNA-209916--- (aa)--
ENST00000496738LMNA-2162405--- (aa)--
ENST00000470199LMNA-211551--- (aa)--
ENST00000502357LMNA-218537--- (aa)--
ENST00000495341LMNA-215394--- (aa)--
ENST00000368297LMNA-2031679-ENSP00000357280491 (aa)-Q5TCI8
ENST00000368299LMNA-2052253-ENSP00000357282614 (aa)-P02545
ENST00000368298LMNA-2041475--- (aa)--
Gene Model
Click here to download ENSG00000160789's gene model file
Pathways
Pathway IDPathway NameSource
hsa04210ApoptosisKEGG
hsa05410Hypertrophic cardiomyopathy (HCM)KEGG
hsa05412Arrhythmogenic right ventricular cardiomyopathy (ARVC)KEGG
hsa05414Dilated cardiomyopathy (DCM)KEGG
Phenotypes
ensgIDTraitpValuePubmed ID
ENSG00000160789Platelet Function Tests1.3511000E-005-
ENSG00000160789Platelet Function Tests6.2900000E-006-
ENSG00000160789Platelet Function Tests8.6800000E-006-
ENSG00000160789Platelet Function Tests1.9100000E-006-
ENSG00000160789Platelet Function Tests9.7600000E-007-
ENSG00000160789Stroke3E-627997041
GWAS
ensgIDSNPChromosomePositionSNP-risk TraitPubmedID95% CIOr or BEAT EFO ID
ENSG00000160789rs1164807931156108585TLung cancer in ever smokers28604730[1.153366335-1.439461007]1.2884976EFO_0006527|EFO_0001071
ENSG00000160789rs587993041156110653?Ischemic stroke27997041z score decrease4.644HP_0002140
ENSG00000160789rs1886258721156114696COvarian cancer30557369[2.17-6.49]3.7593985EFO_0001075
ENSG00000160789rs1129412171156087626CIschemic heart disease in rheumatoid arthritis30251476[2.61-8.87]4.81EFO_0000685|EFO_0001425
ENSG00000160789rs5840251156118735?White blood cell count30595370EFO_0004308
Protein-Protein Interaction (PPI)

Clik here to download ENSG00000160789's network

* RBP PPI network refers to all genes directly bind to RBP
Orthologs identified by RBPome
Ensembl IDGene SymbolCoverageIdentiy OrthologGene SymbolCoverageIdentiy Species
ENSG00000160789LMNA10099.087ENSMUSG00000028063Lmna100100.000Mus_musculus
Gene Ontology
Go IDGo_termPubmedIDEvidenceCategory
GO:0005198structural molecule activity-IEAFunction
GO:0005515protein binding10514485.10727209.11801724.15140953.15161933.15671068.16247757.19323649.19933576.20000738.20580717.20618440.21418524.21949239.21988832.22399800.22555292.23658700.25416956.29568061.29997244.30021884.IPIFunction
GO:0005634nucleus16791210.HDAComponent
GO:0005634nucleus18809582.20810912.IDAComponent
GO:0005635nuclear envelope18606848.27534416.IDAComponent
GO:0005635nuclear envelope21610090.IMPComponent
GO:0005635nuclear envelope-TASComponent
GO:0005638lamin filament-IEAComponent
GO:0005654nucleoplasm27534416.IDAComponent
GO:0005654nucleoplasm-TASComponent
GO:0005829cytosol-TASComponent
GO:0006606protein import into nucleus-IEAProcess
GO:0007084mitotic nuclear envelope reassembly-TASProcess
GO:0008285negative regulation of cell proliferation27534416.IMPProcess
GO:0010628positive regulation of gene expression-IEAProcess
GO:0016607nuclear speck-IEAComponent
GO:0030334regulation of cell migration-ISSProcess
GO:0030951establishment or maintenance of microtubule cytoskeleton polarity-ISSProcess
GO:0031647regulation of protein stability-IEAProcess
GO:0031965nuclear membrane16791210.HDAComponent
GO:0034504protein localization to nucleus-ISSProcess
GO:0036498IRE1-mediated unfolded protein response-TASProcess
GO:0055015ventricular cardiac muscle cell development-IEAProcess
GO:0071456cellular response to hypoxia20810912.IEPProcess
GO:0072201negative regulation of mesenchymal cell proliferation-IEAProcess
GO:0090201negative regulation of release of cytochrome c from mitochondria-IEAProcess
GO:0090343positive regulation of cell aging20458013.IDAProcess
GO:1900114positive regulation of histone H3-K9 trimethylation-IEAProcess
GO:1900180regulation of protein localization to nucleus-IEAProcess
GO:1903243negative regulation of cardiac muscle hypertrophy in response to stress-ISSProcess
GO:2001237negative regulation of extrinsic apoptotic signaling pathway-IEAProcess
To top

Copyright © , Bioinformatics Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, China. All Rights Reserved.

Any comment and suggestion, please contact us