EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
21460252	AMP kinase-related kinase NUAK2 affects tumor growth, migration, and clinical outcome of human melanoma.	Proc Natl Acad Sci U S A	2011 Apr 19	Namiki T	doi: 10.1073/pnas.1007694108
15345718	Identification of SNF1/AMP kinase-related kinase as an NF-kappaB-regulated anti-apoptotic kinase involved in CD95-induced motility and invasiveness.	J Biol Chem	2004 Nov 5	Legembre P	-
18452098	SNARK, a novel downstream molecule of EBV latent membrane protein 1, is associated with resistance to cancer cell death.	Leuk Lymphoma	2008 Jul	Kim JH	doi: 10.1080/10428190802087454.

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
BLCA	chr1	205308634	Missense_Mutation	rs199544834	E151K	0.14
BLCA	chr1	205303674	Missense_Mutation	NA	D555Y	0.13
BLCA	chr1	205304409	Nonsense_Mutation	rs777411761	R310*	0.21
BLCA	chr1	205304212	Silent	novel	K375K	0.58
BLCA	chr1	205321514	Missense_Mutation	NA	A39S	0.17
BLCA	chr1	205311728	Missense_Mutation	NA	P110L	0.19
BLCA	chr1	205321691	5'UTR	novel		0.33
BLCA	chr1	205321598	Missense_Mutation	novel	G11R	0.45
BRCA	chr1	205304207	Missense_Mutation	NA	S377Y	0.21
BRCA	chr1	205306275	Missense_Mutation	NA	H201Q	0.11
BRCA	chr1	205305312	Missense_Mutation	NA	G237V	0.12
BRCA	chr1	205308333	Intron	novel		0.38
BRCA	chr1	205311809	Missense_Mutation	NA	I83T	0.3
BRCA	chr1	205303451	Silent	NA	*629*	0.11
CESC	chr1	205306245	Silent	novel	G211G	0.36
CESC	chr1	205311751	Silent	NA	E102E	0.23
CESC	chr1	205304481	Missense_Mutation	novel	V286M	0.55
CESC	chr1	205308640	Missense_Mutation	novel	E149K	0.39
CESC	chr1	205304048	Missense_Mutation	NA	S430T	0.24
CESC	chr1	205304358	Frame_Shift_Del	novel	*S327Lfs153**	0.1
CESC	chr1	205304360	In_Frame_Del	novel	D326del	0.09
CHOL	chr1	205302185	3'UTR	novel		0.7
COAD	chr1	205303825	Silent	NA	L504L	0.3
COAD	chr1	205308655	Missense_Mutation	rs201895375	R144W	0.24
COAD	chr1	205303671	Nonsense_Mutation	novel	Q556*	0.39
COAD	chr1	205304089	Silent	novel	S416S	0.3
COAD	chr1	205306206	Silent	novel	K224K	0.23
COAD	chr1	205308635	Silent	rs374444303	R150R	0.09
COAD	chr1	205311782	Missense_Mutation	novel	Q92R	0.08
COAD	chr1	205308636	Missense_Mutation	rs558886995	R150H	0.36
COAD	chr1	205303947	Missense_Mutation	novel	E464K	0.48
COAD	chr1	205308618	Missense_Mutation	novel	F156S	0.25
ESCA	chr1	205321585	Missense_Mutation	novel	S15W	0.2
ESCA	chr1	205303948	Silent	rs114413074	P463P	0.47
ESCA	chr1	205306243	Missense_Mutation	novel	S212T	0.86
ESCA	chr1	205321638	5'UTR	novel		0.48
ESCA	chr1	205304278	Missense_Mutation	novel	F353L	0.17
GBM	chr1	205303389	3'UTR	novel		0.33
GBM	chr1	205304285	Missense_Mutation	novel	C351F	0.04
HNSC	chr1	205303774	Silent	rs565958619	F521F	0.15
HNSC	chr1	205321413	Missense_Mutation	novel	E72D	0.32
HNSC	chr1	205303682	Missense_Mutation	novel	E552V	0.16
HNSC	chr1	205303683	Missense_Mutation	novel	E552K	0.17
HNSC	chr1	205321441	Missense_Mutation	NA	T63I	0.15
HNSC	chr1	205303699	Missense_Mutation	rs376539362	D546E	0.26
HNSC	chr1	205306288	Missense_Mutation	novel	S197C	0.27
KIRC	chr1	205303526	Missense_Mutation	NA	C604Y	0.17
KIRC	chr1	205306255	Missense_Mutation	NA	T208K	0.29
KIRP	chr1	205303518	Frame_Shift_Del	novel	L607*	0.38
KIRP	chr1	205321731	5'UTR	novel		0.31
KIRP	chr1	205305261	Missense_Mutation	NA	D254G	0.25
LAML	chr1	205321481	Missense_Mutation	novel	R50W	0.05
LIHC	chr1	205321585	Missense_Mutation	NA	S15L	0.29
LIHC	chr1	205303545	Missense_Mutation	NA	D598H	0.39
LIHC	chr1	205308614	Silent	novel	R157R	0.43
LIHC	chr1	205321475	In_Frame_Del	novel	H44_H51del	0.14
LIHC	chr1	205304164	Silent	rs149020592	T391T	0.29
LUAD	chr1	205303696	Missense_Mutation	NA	S547R	0.31
LUAD	chr1	205321560	Silent	NA	L23L	0.13
LUAD	chr1	205304495	Missense_Mutation	rs765807541	R281L	0.29
LUAD	chr1	205321580	Missense_Mutation	NA	A17P	0.42
LUSC	chr1	205321652	5'UTR	novel		0.45
LUSC	chr1	205303733	Missense_Mutation	NA	R535P	0.42
LUSC	chr1	205303764	Missense_Mutation	NA	D525N	0.48
LUSC	chr1	205303630	Silent	novel	R569R	0.18
LUSC	chr1	205306213	Missense_Mutation	rs763336598	N222S	0.34
LUSC	chr1	205321600	Missense_Mutation	NA	S10F	0.58
OV	chr1	205304215	Silent	NA	L374L	0.24
OV	chr1	205303656	Missense_Mutation	novel	E561K	0.17
OV	chr1	205304255	Missense_Mutation	novel	G361V	0.05
OV	chr1	205308164	Splice_Site	NA	X190_splice	0.55
OV	chr1	205321715	5'UTR	novel		0.46
OV	chr1	205304185	Silent	NA	A384A	0.34
OV	chr1	205303693	In_Frame_Ins	novel	I548_L549insTGA	0.11
OV	chr1	205303695	Frame_Shift_Ins	novel	*I548Lfs12**	0.11
PAAD	chr1	205303632	Missense_Mutation	rs561905076	R569W	0.19
PAAD	chr1	205306227	Silent	rs377400744	S217S	0.19
PAAD	chr1	205303908	Missense_Mutation	rs762199327	V477M	0.11
READ	chr1	205308707	Frame_Shift_Del	NA	*V126Sfs132**	0.25
SARC	chr1	205303418	3'UTR	novel		0.14
SARC	chr1	205302422	3'UTR	novel		0.3
SKCM	chr1	205321599	Silent	novel	S10S	0.06
SKCM	chr1	205308634	Missense_Mutation	rs199544834	E151K	0.39
SKCM	chr1	205306285	Missense_Mutation	rs114209340	N198S	0.18
SKCM	chr1	205303987	Silent	NA	K450K	0.3
SKCM	chr1	205303851	Missense_Mutation	rs752515472	L496F	0.29
SKCM	chr1	205303340	3'UTR	novel		0.53
SKCM	chr1	205303736	Missense_Mutation	NA	A534V	0.36
SKCM	chr1	205304065	Silent	NA	E424E	0.4
SKCM	chr1	205304067	Missense_Mutation	NA	E424K	0.24
SKCM	chr1	205304302	Silent	NA	E345E	0.4
SKCM	chr1	205303603	Silent	rs753204808	T578T	0.43
SKCM	chr1	205304422	Nonsense_Mutation	novel	W305*	0.45
SKCM	chr1	205304075	Missense_Mutation	novel	G421A	0.18
SKCM	chr1	205304067	Missense_Mutation	NA	E424K	0.39
SKCM	chr1	205306188	Splice_Region	novel	E230E	0.53
SKCM	chr1	205321568	Frame_Shift_Del	novel	*R21Gfs7**	0.39
SKCM	chr1	205303375	3'UTR	novel		0.57
SKCM	chr1	205304219	Missense_Mutation	rs768146177	S373L	0.22
SKCM	chr1	205303692	Silent	NA	L549L	0.48
SKCM	chr1	205303982	Missense_Mutation	NA	P452L	0.15
SKCM	chr1	205304376	Missense_Mutation	novel	G321W	0.11
SKCM	chr1	205304041	Silent	rs767475839	I432I	0.38
SKCM	chr1	205308617	Silent	NA	F156F	0.26
SKCM	chr1	205321553	Missense_Mutation	NA	G26R	0.15
SKCM	chr1	205305227	Silent	novel	G265G	0.34
SKCM	chr1	205311769	Silent	NA	H96H	0.06
SKCM	chr1	205303519	Silent	NA	S606S	0.42
SKCM	chr1	205304312	Missense_Mutation	NA	P342L	0.2
SKCM	chr1	205303606	Silent	NA	L577L	0.32
SKCM	chr1	205303768	Silent	NA	S523S	0.27
SKCM	chr1	205303517	Missense_Mutation	novel	L607P	0.34
SKCM	chr1	205303845	Missense_Mutation	rs143749181	R498C	0.48
STAD	chr1	205304490	Silent	novel	L283L	0.44
STAD	chr1	205308598	Missense_Mutation	rs752932851	V163M	0.35
STAD	chr1	205304310	Frame_Shift_Del	novel	*L343Sfs137**	0.2
STAD	chr1	205304056	Silent	rs778951173	P427P	0.17
STAD	chr1	205308581	Splice_Region	novel	Q168Q	0.33
TGCT	chr1	205305258	Missense_Mutation	novel	H255L	0.14
UCEC	chr1	205306227	Silent	rs377400744	S217S	0.45
UCEC	chr1	205303239	3'UTR	novel		0.36
UCEC	chr1	205304441	Missense_Mutation	novel	S299I	0.58
UCEC	chr1	205308720	Missense_Mutation	NA	S122I	0.19
UCEC	chr1	205311827	Splice_Site	NA	X78_splice	0.31
UCEC	chr1	205303998	Missense_Mutation	novel	G447S	0.18
UCEC	chr1	205303909	Silent	rs773783442	D476D	0.33
UCEC	chr1	205302214	3'UTR	novel		0.38
UCEC	chr1	205304228	Missense_Mutation	rs773889103	R370H	0.4
UCEC	chr1	205303632	Missense_Mutation	rs561905076	R569W	0.45
UCEC	chr1	205303294	3'UTR	novel		0.86
UCEC	chr1	205304233	Silent	novel	L368L	0.14
UCEC	chr1	205302207	3'UTR	novel		0.18
UCEC	chr1	205308593	Missense_Mutation	novel	H164Q	0.35
UCEC	chr1	205303844	Missense_Mutation	rs753606733	R498H	0.38
UCEC	chr1	205303792	Silent	rs772106881	L515L	0.41
UCEC	chr1	205308704	Silent	NA	I127I	0.34
UCEC	chr1	205303492	Silent	rs370514883	A615A	0.4
UCEC	chr1	205304057	Missense_Mutation	rs748472624	P427L	0.48
UCEC	chr1	205305229	Missense_Mutation	rs780926337	G265R	0.38
UCEC	chr1	205306262	Silent	novel	L206L	0.3
UCEC	chr1	205302195	3'UTR	novel		0.31
UCEC	chr1	205308215	Nonsense_Mutation	rs376798957	R174*	0.47
UCEC	chr1	205302276	3'UTR	novel		0.33
UCEC	chr1	205304187	Missense_Mutation	novel	A384T	0.21
UCEC	chr1	205303817	Missense_Mutation	novel	K507T	0.23
UCEC	chr1	205308209	Missense_Mutation	novel	L176I	0.17
UCEC	chr1	205308635	Silent	rs374444303	R150R	0.38
UCEC	chr1	205303844	Missense_Mutation	rs753606733	R498H	0.24
UCEC	chr1	205321499	Missense_Mutation	novel	H44N	0.46
UCEC	chr1	205304229	Missense_Mutation	rs571070763	R370C	0.29
UCEC	chr1	205308637	Missense_Mutation	rs376326465	R150C	0.42
UCEC	chr1	205302395	3'UTR	novel		0.45
UCS	chr1	205321512	Silent	novel	A39A	0.08

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BLCA	DEL	0.0858	0.033566
DLBC	DEL	0.0417	0.0017831
KIRC	AMP	0.0871	0.059566
READ	AMP	0.2667	0.14328
TGCT	AMP	0.3467	0.088103
TGCT	DEL	0.0133	0.16985
THCA	AMP	0.0481	0.075436

Survival Analysis

Cancer	P-value	Q-value
SKCM	0.0015	Kaplan-Meier Survival Analysis
LUSC	0.029	Kaplan-Meier Survival Analysis
BRCA	0.034	Kaplan-Meier Survival Analysis
KIRP	0.045	Kaplan-Meier Survival Analysis
PAAD	0.0001	Kaplan-Meier Survival Analysis
LAML	0.022	Kaplan-Meier Survival Analysis
KICH	0.0063	Kaplan-Meier Survival Analysis
UCEC	0.00016	Kaplan-Meier Survival Analysis
GBM	0.0071	Kaplan-Meier Survival Analysis
LIHC	0.025	Kaplan-Meier Survival Analysis
THCA	0.019	Kaplan-Meier Survival Analysis
UVM	0.00044	Kaplan-Meier Survival Analysis

Description

RBDs

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000163545 (Gene tree)
Gene ID: 81788
Gene Symbol: NUAK2
Alias: SNARK|FLJ90349
Full Name: NUAK family kinase 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 19,733 bases
Position: chr1:205,302,059-205,321,791
Accession: 29558
RBP type: canonical RBP
Summary: NUAK2 (NUAK Family Kinase 2) is a Protein Coding gene. Among its related pathways are Apoptosis and Autophagy and Cytoskeletal Signaling. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is NUAK1.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000356125	RIO1	PF01163.22	0.00012	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000367157	NUAK2-201	3441	-	ENSP00000356125	672 (aa)	-	Q9H093

Gene Model

Click here to download ENSG00000163545's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000163545's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000163545	NUAK2	88	59.612	ENSAPOG00000000485	nuak2	94	59.612	Acanthochromis_polyacanthus
ENSG00000163545	NUAK2	98	83.934	ENSAMEG00000001435	NUAK2	100	83.934	Ailuropoda_melanoleuca
ENSG00000163545	NUAK2	66	66.904	ENSACIG00000017871	-	98	46.747	Amphilophus_citrinellus
ENSG00000163545	NUAK2	89	58.937	ENSACIG00000019490	nuak2	94	58.937	Amphilophus_citrinellus
ENSG00000163545	NUAK2	88	59.547	ENSAOCG00000022359	nuak2	98	57.947	Amphiprion_ocellaris
ENSG00000163545	NUAK2	88	59.935	ENSAPEG00000014640	nuak2	94	59.935	Amphiprion_percula
ENSG00000163545	NUAK2	77	47.466	ENSATEG00000003834	si:ch211-117c9.1	85	48.048	Anabas_testudineus
ENSG00000163545	NUAK2	88	59.477	ENSATEG00000006373	nuak2	94	59.477	Anabas_testudineus
ENSG00000163545	NUAK2	88	61.755	ENSACAG00000014491	NUAK2	98	61.622	Anolis_carolinensis
ENSG00000163545	NUAK2	93	95.701	ENSANAG00000023561	NUAK2	100	95.701	Aotus_nancymaae
ENSG00000163545	NUAK2	88	58.987	ENSACLG00000022385	nuak2	93	58.987	Astatotilapia_calliptera
ENSG00000163545	NUAK2	77	48.328	ENSACLG00000009680	si:ch211-117c9.1	84	48.658	Astatotilapia_calliptera
ENSG00000163545	NUAK2	87	56.844	ENSAMXG00000036486	nuak2	96	57.393	Astyanax_mexicanus
ENSG00000163545	NUAK2	93	95.064	ENSCJAG00000040262	NUAK2	100	95.064	Callithrix_jacchus
ENSG00000163545	NUAK2	90	87.336	ENSCAFG00000010038	NUAK2	99	83.333	Canis_familiaris
ENSG00000163545	NUAK2	90	87.336	ENSCAFG00020005323	NUAK2	100	86.120	Canis_lupus_dingo
ENSG00000163545	NUAK2	93	84.261	ENSCHIG00000013817	NUAK2	100	84.261	Capra_hircus
ENSG00000163545	NUAK2	99	88.593	ENSTSYG00000033748	NUAK2	99	89.630	Carlito_syrichta
ENSG00000163545	NUAK2	93	84.664	ENSCPOG00000011773	NUAK2	100	85.446	Cavia_porcellus
ENSG00000163545	NUAK2	93	95.223	ENSCCAG00000019631	NUAK2	100	95.223	Cebus_capucinus
ENSG00000163545	NUAK2	100	97.024	ENSCATG00000044068	NUAK2	100	97.024	Cercocebus_atys
ENSG00000163545	NUAK2	93	83.851	ENSCLAG00000012570	NUAK2	100	83.851	Chinchilla_lanigera
ENSG00000163545	NUAK2	100	97.321	ENSCSAG00000014618	NUAK2	100	97.321	Chlorocebus_sabaeus
ENSG00000163545	NUAK2	90	63.764	ENSCPBG00000001503	NUAK2	98	63.764	Chrysemys_picta_bellii
ENSG00000163545	NUAK2	100	96.875	ENSCANG00000038643	NUAK2	100	96.875	Colobus_angolensis_palliatus
ENSG00000163545	NUAK2	88	60.065	ENSCSEG00000002218	nuak2	97	60.065	Cynoglossus_semilaevis
ENSG00000163545	NUAK2	88	59.083	ENSCVAG00000023192	nuak2	96	59.083	Cyprinodon_variegatus
ENSG00000163545	NUAK2	77	47.069	ENSCVAG00000015427	si:ch211-117c9.1	84	47.069	Cyprinodon_variegatus
ENSG00000163545	NUAK2	88	57.699	ENSDARG00000063661	nuak2	96	57.699	Danio_rerio
ENSG00000163545	NUAK2	90	84.959	ENSDNOG00000031509	NUAK2	96	84.244	Dasypus_novemcinctus
ENSG00000163545	NUAK2	93	84.735	ENSDORG00000013111	Nuak2	100	84.735	Dipodomys_ordii
ENSG00000163545	NUAK2	72	44.467	ENSEBUG00000004356	nuak2	89	44.309	Eptatretus_burgeri
ENSG00000163545	NUAK2	93	88.486	ENSEASG00005005777	NUAK2	100	88.486	Equus_asinus_asinus
ENSG00000163545	NUAK2	93	88.013	ENSECAG00000014699	NUAK2	100	88.013	Equus_caballus
ENSG00000163545	NUAK2	93	83.699	ENSEEUG00000011132	NUAK2	100	83.856	Erinaceus_europaeus
ENSG00000163545	NUAK2	73	49.186	ENSELUG00000002633	si:ch211-117c9.1	82	48.980	Esox_lucius
ENSG00000163545	NUAK2	88	59.128	ENSELUG00000014173	nuak2	92	59.481	Esox_lucius
ENSG00000163545	NUAK2	98	86.233	ENSFCAG00000043568	NUAK2	100	86.233	Felis_catus
ENSG00000163545	NUAK2	75	67.892	ENSFALG00000000621	NUAK2	99	68.472	Ficedula_albicollis
ENSG00000163545	NUAK2	82	46.384	ENSFHEG00000018818	-	88	46.384	Fundulus_heteroclitus
ENSG00000163545	NUAK2	87	58.785	ENSGMOG00000008068	nuak2	99	58.785	Gadus_morhua
ENSG00000163545	NUAK2	90	63.863	ENSGALG00000036616	NUAK2	98	63.863	Gallus_gallus
ENSG00000163545	NUAK2	77	48.241	ENSGAFG00000006164	si:ch211-117c9.1	85	48.490	Gambusia_affinis
ENSG00000163545	NUAK2	89	57.818	ENSGAFG00000021595	nuak2	96	58.537	Gambusia_affinis
ENSG00000163545	NUAK2	88	57.929	ENSGACG00000001061	nuak2	99	58.091	Gasterosteus_aculeatus
ENSG00000163545	NUAK2	90	63.932	ENSGAGG00000011826	NUAK2	99	63.969	Gopherus_agassizii
ENSG00000163545	NUAK2	100	98.958	ENSGGOG00000003525	NUAK2	100	98.958	Gorilla_gorilla
ENSG00000163545	NUAK2	88	59.150	ENSHBUG00000002854	nuak2	99	58.626	Haplochromis_burtoni
ENSG00000163545	NUAK2	93	84.820	ENSHGLG00000018780	NUAK2	100	84.820	Heterocephalus_glaber_female
ENSG00000163545	NUAK2	93	84.820	ENSHGLG00100004449	NUAK2	100	84.820	Heterocephalus_glaber_male
ENSG00000163545	NUAK2	80	44.975	ENSHCOG00000001701	si:ch211-117c9.1	91	44.975	Hippocampus_comes
ENSG00000163545	NUAK2	89	55.626	ENSIPUG00000017552	nuak2	97	56.731	Ictalurus_punctatus
ENSG00000163545	NUAK2	93	87.520	ENSSTOG00000026121	NUAK2	100	87.678	Ictidomys_tridecemlineatus
ENSG00000163545	NUAK2	93	86.414	ENSJJAG00000022561	Nuak2	100	86.414	Jaculus_jaculus
ENSG00000163545	NUAK2	87	59.350	ENSKMAG00000021452	nuak2	94	59.350	Kryptolebias_marmoratus
ENSG00000163545	NUAK2	88	59.481	ENSLBEG00000013643	nuak2	93	59.643	Labrus_bergylta
ENSG00000163545	NUAK2	91	62.780	ENSLACG00000009120	NUAK2	97	62.780	Latimeria_chalumnae
ENSG00000163545	NUAK2	100	96.875	ENSMFAG00000038432	NUAK2	100	96.875	Macaca_fascicularis
ENSG00000163545	NUAK2	100	96.726	ENSMMUG00000018584	NUAK2	100	96.726	Macaca_mulatta
ENSG00000163545	NUAK2	100	96.726	ENSMNEG00000035837	NUAK2	100	96.726	Macaca_nemestrina
ENSG00000163545	NUAK2	100	97.321	ENSMLEG00000040864	NUAK2	100	97.321	Mandrillus_leucophaeus
ENSG00000163545	NUAK2	89	58.280	ENSMAMG00000023908	nuak2	99	58.280	Mastacembelus_armatus
ENSG00000163545	NUAK2	77	47.295	ENSMAMG00000010172	si:ch211-117c9.1	83	48.780	Mastacembelus_armatus
ENSG00000163545	NUAK2	77	50.838	ENSMZEG00005027060	si:ch211-117c9.1	84	49.186	Maylandia_zebra
ENSG00000163545	NUAK2	88	58.987	ENSMZEG00005011074	nuak2	96	57.895	Maylandia_zebra
ENSG00000163545	NUAK2	70	71.489	ENSMGAG00000002936	NUAK2	99	71.489	Meleagris_gallopavo
ENSG00000163545	NUAK2	93	84.639	ENSMAUG00000017535	Nuak2	100	84.639	Mesocricetus_auratus
ENSG00000163545	NUAK2	99	86.596	ENSMICG00000000056	NUAK2	99	88.031	Microcebus_murinus
ENSG00000163545	NUAK2	93	85.737	ENSMOCG00000020262	Nuak2	100	85.737	Microtus_ochrogaster
ENSG00000163545	NUAK2	52	82.192	ENSMODG00000001769	-	99	82.369	Monodelphis_domestica
ENSG00000163545	NUAK2	87	59.272	ENSMALG00000018179	nuak2	95	59.768	Monopterus_albus
ENSG00000163545	NUAK2	76	45.965	ENSMALG00000010356	si:ch211-117c9.1	84	46.350	Monopterus_albus
ENSG00000163545	NUAK2	93	85.512	MGP_CAROLIEiJ_G0014585	Nuak2	100	85.512	Mus_caroli
ENSG00000163545	NUAK2	90	87.561	ENSMUSG00000009772	Nuak2	100	85.669	Mus_musculus
ENSG00000163545	NUAK2	90	86.907	MGP_PahariEiJ_G0027821	Nuak2	100	85.039	Mus_pahari
ENSG00000163545	NUAK2	93	85.827	MGP_SPRETEiJ_G0015392	Nuak2	99	86.869	Mus_spretus
ENSG00000163545	NUAK2	100	82.318	ENSMLUG00000011425	NUAK2	100	82.467	Myotis_lucifugus
ENSG00000163545	NUAK2	77	50.560	ENSNBRG00000020753	si:ch211-117c9.1	84	50.560	Neolamprologus_brichardi
ENSG00000163545	NUAK2	87	57.072	ENSNBRG00000006567	nuak2	96	57.237	Neolamprologus_brichardi
ENSG00000163545	NUAK2	100	97.470	ENSNLEG00000014473	NUAK2	100	97.470	Nomascus_leucogenys
ENSG00000163545	NUAK2	59	94.937	ENSOPRG00000010168	NUAK2	63	94.937	Ochotona_princeps
ENSG00000163545	NUAK2	93	85.446	ENSODEG00000006060	NUAK2	100	85.759	Octodon_degus
ENSG00000163545	NUAK2	77	51.630	ENSONIG00000012465	si:ch211-117c9.1	99	51.630	Oreochromis_niloticus
ENSG00000163545	NUAK2	88	58.920	ENSONIG00000018929	nuak2	99	58.920	Oreochromis_niloticus
ENSG00000163545	NUAK2	73	86.410	ENSOCUG00000002318	NUAK2	100	86.410	Oryctolagus_cuniculus
ENSG00000163545	NUAK2	77	48.398	ENSORLG00000023101	si:ch211-117c9.1	90	48.229	Oryzias_latipes
ENSG00000163545	NUAK2	88	58.374	ENSORLG00000000229	nuak2	95	59.253	Oryzias_latipes
ENSG00000163545	NUAK2	91	57.437	ENSORLG00020008332	nuak2	99	58.136	Oryzias_latipes_hni
ENSG00000163545	NUAK2	77	47.700	ENSORLG00020003401	si:ch211-117c9.1	90	48.229	Oryzias_latipes_hni
ENSG00000163545	NUAK2	91	57.528	ENSORLG00015000637	nuak2	99	58.059	Oryzias_latipes_hsok
ENSG00000163545	NUAK2	88	59.091	ENSOMEG00000015088	nuak2	97	59.643	Oryzias_melastigma
ENSG00000163545	NUAK2	78	47.279	ENSOMEG00000013190	si:ch211-117c9.1	89	47.538	Oryzias_melastigma
ENSG00000163545	NUAK2	93	89.731	ENSOGAG00000013071	NUAK2	100	89.731	Otolemur_garnettii
ENSG00000163545	NUAK2	99	76.831	ENSOARG00000003826	NUAK2	94	79.653	Ovis_aries
ENSG00000163545	NUAK2	100	98.661	ENSPPAG00000032571	NUAK2	100	98.661	Pan_paniscus
ENSG00000163545	NUAK2	98	86.082	ENSPPRG00000013755	NUAK2	100	86.082	Panthera_pardus
ENSG00000163545	NUAK2	82	88.989	ENSPTIG00000005428	NUAK2	85	88.989	Panthera_tigris_altaica
ENSG00000163545	NUAK2	100	98.512	ENSPTRG00000001897	NUAK2	100	98.512	Pan_troglodytes
ENSG00000163545	NUAK2	100	97.173	ENSPANG00000018147	NUAK2	100	97.173	Papio_anubis
ENSG00000163545	NUAK2	89	56.129	ENSPKIG00000001753	nuak2	95	57.440	Paramormyrops_kingsleyae
ENSG00000163545	NUAK2	88	64.715	ENSPSIG00000009103	NUAK2	100	64.715	Pelodiscus_sinensis
ENSG00000163545	NUAK2	80	47.193	ENSPMGG00000005991	si:ch211-117c9.1	88	47.193	Periophthalmus_magnuspinnatus
ENSG00000163545	NUAK2	93	77.638	ENSPCIG00000004437	NUAK2	100	77.638	Phascolarctos_cinereus
ENSG00000163545	NUAK2	77	50.088	ENSPFOG00000009064	-	97	50.265	Poecilia_formosa
ENSG00000163545	NUAK2	88	57.699	ENSPFOG00000000376	nuak2	96	58.387	Poecilia_formosa
ENSG00000163545	NUAK2	77	48.142	ENSPLAG00000010229	-	84	48.649	Poecilia_latipinna
ENSG00000163545	NUAK2	88	58.548	ENSPLAG00000013584	nuak2	96	58.548	Poecilia_latipinna
ENSG00000163545	NUAK2	77	48.142	ENSPMEG00000006856	si:ch211-117c9.1	84	48.649	Poecilia_mexicana
ENSG00000163545	NUAK2	88	58.143	ENSPMEG00000004656	nuak2	96	58.862	Poecilia_mexicana
ENSG00000163545	NUAK2	77	48.403	ENSPREG00000018548	si:ch211-117c9.1	84	48.908	Poecilia_reticulata
ENSG00000163545	NUAK2	89	58.805	ENSPREG00000004466	nuak2	96	58.805	Poecilia_reticulata
ENSG00000163545	NUAK2	93	99.363	ENSPPYG00000000307	NUAK2	100	99.363	Pongo_abelii
ENSG00000163545	NUAK2	93	87.898	ENSPCAG00000015229	NUAK2	100	87.898	Procavia_capensis
ENSG00000163545	NUAK2	100	87.297	ENSPCOG00000023513	NUAK2	100	87.888	Propithecus_coquereli
ENSG00000163545	NUAK2	92	57.232	ENSPNYG00000007903	nuak2	99	57.232	Pundamilia_nyererei
ENSG00000163545	NUAK2	91	55.694	ENSPNAG00000001964	nuak2	98	56.899	Pygocentrus_nattereri
ENSG00000163545	NUAK2	100	96.280	ENSRBIG00000012566	NUAK2	100	96.280	Rhinopithecus_bieti
ENSG00000163545	NUAK2	100	96.280	ENSRROG00000037807	NUAK2	100	96.280	Rhinopithecus_roxellana
ENSG00000163545	NUAK2	93	95.382	ENSSBOG00000020563	NUAK2	100	95.382	Saimiri_boliviensis_boliviensis
ENSG00000163545	NUAK2	98	76.212	ENSSHAG00000014222	NUAK2	98	76.212	Sarcophilus_harrisii
ENSG00000163545	NUAK2	87	60.768	ENSSFOG00015016369	nuak2	99	60.768	Scleropages_formosus
ENSG00000163545	NUAK2	77	46.745	ENSSMAG00000008945	si:ch211-117c9.1	84	48.311	Scophthalmus_maximus
ENSG00000163545	NUAK2	87	59.770	ENSSDUG00000009077	nuak2	93	59.770	Seriola_dumerili
ENSG00000163545	NUAK2	81	46.178	ENSSDUG00000016779	si:ch211-117c9.1	87	46.815	Seriola_dumerili
ENSG00000163545	NUAK2	81	46.709	ENSSLDG00000025370	-	87	47.115	Seriola_lalandi_dorsalis
ENSG00000163545	NUAK2	87	59.641	ENSSLDG00000022806	nuak2	93	59.606	Seriola_lalandi_dorsalis
ENSG00000163545	NUAK2	92	63.581	ENSSPUG00000014390	NUAK2	99	63.733	Sphenodon_punctatus
ENSG00000163545	NUAK2	77	47.611	ENSSPAG00000019755	si:ch211-117c9.1	86	47.941	Stegastes_partitus
ENSG00000163545	NUAK2	89	59.271	ENSSPAG00000013352	nuak2	95	59.271	Stegastes_partitus
ENSG00000163545	NUAK2	87	89.492	ENSSSCG00000038471	NUAK2	99	89.492	Sus_scrofa
ENSG00000163545	NUAK2	78	46.656	ENSTRUG00000020777	si:ch211-117c9.1	83	47.049	Takifugu_rubripes
ENSG00000163545	NUAK2	87	59.967	ENSTRUG00000023948	nuak2	93	60.132	Takifugu_rubripes
ENSG00000163545	NUAK2	78	50.000	ENSTNIG00000001456	si:ch211-117c9.1	100	50.266	Tetraodon_nigroviridis
ENSG00000163545	NUAK2	67	88.053	ENSTTRG00000006600	NUAK2	100	88.274	Tursiops_truncatus
ENSG00000163545	NUAK2	93	88.170	ENSUAMG00000003216	NUAK2	100	88.170	Ursus_americanus
ENSG00000163545	NUAK2	91	80.098	ENSUMAG00000003830	NUAK2	100	78.639	Ursus_maritimus
ENSG00000163545	NUAK2	93	86.120	ENSVVUG00000013705	NUAK2	100	86.435	Vulpes_vulpes
ENSG00000163545	NUAK2	88	53.920	ENSXETG00000000974	nuak2	99	54.180	Xenopus_tropicalis
ENSG00000163545	NUAK2	87	58.706	ENSXCOG00000003678	nuak2	100	82.061	Xiphophorus_couchianus
ENSG00000163545	NUAK2	77	48.485	ENSXMAG00000007457	si:ch211-117c9.1	84	48.735	Xiphophorus_maculatus
ENSG00000163545	NUAK2	88	58.728	ENSXMAG00000025530	nuak2	96	58.728	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000287	magnesium ion binding	14976552.	IDA	Function
GO:0004674	protein serine/threonine kinase activity	21873635.	IBA	Function
GO:0004674	protein serine/threonine kinase activity	14976552.19927127.	IDA	Function
GO:0005515	protein binding	19927127.	IPI	Function
GO:0005524	ATP binding	14976552.	IDA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0006468	protein phosphorylation	21873635.	IBA	Process
GO:0006468	protein phosphorylation	14976552.	IDA	Process
GO:0006915	apoptotic process	-	IEA	Process
GO:0030036	actin cytoskeleton organization	14575707.	IDA	Process
GO:0035556	intracellular signal transduction	21873635.	IBA	Process
GO:0042149	cellular response to glucose starvation	14575707.	IDA	Process
GO:0043066	negative regulation of apoptotic process	15345718.	IDA	Process

Note: Click here to get the extension of tumor abbreviations.

Note: to get the extension of tumor abbreviations.