EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
21789020	Expression of AIMP1, 2 and 3, the scaffolds for the multi-tRNA synthetase complex, is downregulated in gastric and colorectal cancer.	Tumori	2011 May-Jun	Kim SS	doi: 10.1700/912.10038.
19573982	Antitumor activity and pharmacokinetic properties of ARS-interacting multi-functional protein 1 (AIMP1/p43).	Cancer Lett	2010 Jan 28	Han JM	doi: 10.1016/j.canlet.2009.06.005
18951814	The impact of Meth A fibrosarcoma derived EMAP II on dendritic cell migration.	Cytokine	2008 Nov	Haridas S	doi: 10.1016/j.cyto.2008.09.002
19002109	Endothelial monocyte activating polypeptide II interferes with VEGF-induced proangiogenic signaling.	Lab Invest	2009 Jan	Awasthi N	doi: 10.1038/labinvest.2008.106
14688335	Colorectal cancer cells induce lymphocyte apoptosis by an endothelial monocyte-activating polypeptide-II-dependent mechanism.	J Immunol	2004 Jan 1	Murray JC	-
24395571	Kisspeptin effect on endothelial monocyte activating polypeptide II (EMAP-II)-associated lymphocyte cell death and metastases in colorectal cancer patients.	Mol Med	2014 Mar 18	Stathaki M	doi: 10.2119/molmed.2013.00151.

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr4	106324985	Splice_Region	novel		0.39
BLCA	chr4	106331812	Missense_Mutation	novel	E178Q	0.52
BLCA	chr4	106328140	Silent	NA	V96V	0.23
BRCA	chr4	106328123	Missense_Mutation	rs770399051	M91V	0.31
CESC	chr4	106347670	Missense_Mutation	rs564105201	M306T	0.19
CESC	chr4	106316514	Intron	rs748508527		0.46
COAD	chr4	106328165	Missense_Mutation	novel	V105I	0.1
COAD	chr4	106327486	Nonsense_Mutation	rs373122636	R49*	0.32
DLBC	chr4	106324995	5'UTR	rs751610778		0.23
ESCA	chr4	106327476	Missense_Mutation	novel	E45D	0.12
ESCA	chr4	106325058	Missense_Mutation	novel	E17Q	0.2
GBM	chr4	106327455	Silent	NA	L38L	0.23
HNSC	chr4	106331824	Missense_Mutation	rs148281523	G182R	0.13	tRNA_bind
HNSC	chr4	106328237	Frame_Shift_Ins	novel	*K129Ifs24**	0.13
KIRC	chr4	106331791	Missense_Mutation	NA	A171T	0.4
LAML	chr4	106331703	Missense_Mutation	novel	I141M	0.05
LGG	chr4	106331883	Missense_Mutation	novel	Q201H	0.34	tRNA_bind
LUAD	chr4	106336931	Missense_Mutation	novel	L222F	0.25	tRNA_bind
LUAD	chr4	106347565	Missense_Mutation	novel	W271L	0.33	tRNA_bind
LUAD	chr4	106328243	Missense_Mutation	novel	G131R	0.18
LUSC	chr4	106336949	Missense_Mutation	novel	M228I	0.33	tRNA_bind
LUSC	chr4	106331677	Missense_Mutation	novel	K133Q	0.48
LUSC	chr4	106331707	Missense_Mutation	NA	G143R	0.42
LUSC	chr4	106336892	Silent	novel	L209L	0.28
OV	chr4	106325088	Nonsense_Mutation	novel	Q27*	0.14
OV	chr4	106331783	Missense_Mutation	novel	H168L	0.08
OV	chr4	106347710	3'UTR	novel		0.12
PAAD	chr4	106328220	Missense_Mutation	rs750047860	A123V	0.07
SKCM	chr4	106337004	Missense_Mutation	rs748529660	P247S	0.37	tRNA_bind
SKCM	chr4	106328243	Missense_Mutation	novel	G131R	0.33
SKCM	chr4	106331870	Missense_Mutation	NA	V197A	0.39	tRNA_bind
SKCM	chr4	106327486	Nonsense_Mutation	rs373122636	R49*	0.11
STAD	chr4	106324995	5'UTR	rs751610778		0.14
STAD	chr4	106331686	Frame_Shift_Del	NA	*K137Nfs5**	0.48
STAD	chr4	106331741	Missense_Mutation	rs202139899	R154H	0.12
UCEC	chr4	106327487	Missense_Mutation	rs747675209	R49Q	0.34
UCEC	chr4	106331798	Missense_Mutation	rs143219988	S173Y	0.37
UCEC	chr4	106347661	Missense_Mutation	novel	A303D	0.43
UCEC	chr4	106347774	3'UTR	novel		0.63
UCEC	chr4	106327462	Missense_Mutation	novel	T41P	0.38
UCEC	chr4	106347554	Missense_Mutation	novel	K267N	0.24	tRNA_bind
UCEC	chr4	106327486	Nonsense_Mutation	rs373122636	R49*	0.46
UCEC	chr4	106327487	Missense_Mutation	rs747675209	R49Q	0.45
UCEC	chr4	106331753	Missense_Mutation	rs777680841	R158Q	0.39
UCEC	chr4	106325028	Missense_Mutation	novel	V7F	0.06
UCEC	chr4	106327455	Silent	NA	L38L	0.36
UCEC	chr4	106331827	Nonsense_Mutation	novel	E183*	0.16	tRNA_bind
UCEC	chr4	106327486	Nonsense_Mutation	rs373122636	R49*	0.6
UCEC	chr4	106336878	Missense_Mutation	novel	R205W	0.46	tRNA_bind
UCEC	chr4	106337020	Missense_Mutation	novel	T252N	0.09	tRNA_bind
UCEC	chr4	106316537	Intron	novel		0.33
UCEC	chr4	106328215	Missense_Mutation	rs143898497	K121N	0.27
UCEC	chr4	106331798	Missense_Mutation	rs143219988	S173Y	0.39
UCEC	chr4	106328227	Silent	novel	E125E	0.35
UCEC	chr4	106337014	Missense_Mutation	novel	R250I	0.53	tRNA_bind
UCEC	chr4	106347656	Silent	novel	C301C	0.21
UCEC	chr4	106331792	Missense_Mutation	NA	A171V	0.34
UCS	chr4	106331752	Nonsense_Mutation	rs755959621	R158*	0.37

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
LIHC	DEL	0.4351	7.0927e-07
LUAD	DEL	0.1938	0.050802
MESO	DEL	0.4138	0.075661

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.00069	Kaplan-Meier Survival Analysis
MESO	0.0011	Kaplan-Meier Survival Analysis
ACC	0.034	Kaplan-Meier Survival Analysis
UCS	0.041	Kaplan-Meier Survival Analysis
HNSC	0.0001	Kaplan-Meier Survival Analysis
SKCM	0.00032	Kaplan-Meier Survival Analysis
PRAD	0.021	Kaplan-Meier Survival Analysis
BRCA	0.0041	Kaplan-Meier Survival Analysis
BLCA	0.034	Kaplan-Meier Survival Analysis
KICH	0.03	Kaplan-Meier Survival Analysis
LIHC	0.013	Kaplan-Meier Survival Analysis
LUAD	0.011	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000164022 (Gene tree)
Gene ID: 9255
Gene Symbol: AIMP1
Alias: EMAPII|EMAP-2|p43|SCYE1
Full Name: aminoacyl tRNA synthetase complex interacting multifunctional protein 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 33,683 bases
Position: chr4:106,315,544-106,349,226
Accession: 10648
RBP type: canonical RBP
Summary: The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20. [provided by RefSeq, Dec 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000350699	tRNA_bind	PF01588.20	2.1e-29	1	1
ENSP00000405248	tRNA_bind	PF01588.20	2.1e-29	1	1
ENSP00000378191	tRNA_bind	PF01588.20	4e-29	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
10852899	A novel anti-tumor cytokine contains an RNA binding motif present in aminoacyl-tRNA synthetases.	J Biol Chem	2000 Sep 1	Kim Y	-
15078106	The tRNA-interacting factor p43 associates with mammalian arginyl-tRNA synthetase but does not modify its tRNA aminoacylation properties.	Biochemistry	2004 Apr 20	Guigou L	-
9405472	The p43 component of the mammalian multi-synthetase complex is likely to be the precursor of the endothelial monocyte-activating polypeptide II cytokine.	J Biol Chem	1997 Dec 19	Quevillon S	-
11306575	The EMAPII cytokine is released from the mammalian multisynthetase complex after cleavage of its p43/proEMAPII component.	J Biol Chem	2001 Jun 29	Shalak V	-
9822632	Secondary structure for the apolipoprotein B mRNA editing site. Au-binding proteins interact with a stem loop.	J Biol Chem	1998 Nov 27	Richardson N	-
11118226	A recurrent general RNA binding domain appended to plant methionyl-tRNA synthetase acts as a cis-acting cofactor for aminoacylation.	EMBO J	2000 Dec 15	Kaminska M	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000510207	AIMP1-204	568	-	ENSP00000423681	150 (aa)	-	D6R937
ENST00000394701	AIMP1-202	2586	-	ENSP00000378191	336 (aa)	-	Q12904
ENST00000442366	AIMP1-203	2519	-	ENSP00000405248	312 (aa)	-	Q12904
ENST00000358008	AIMP1-201	2412	XM_017008835	ENSP00000350699	312 (aa)	XP_016864324	Q12904

Gene Model

Click here to download ENSG00000164022's gene model file

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000164022	rs13534	4	106348870	A	Male-pattern baldness	30573740	[0.02-0.034] unit decrease	0.0273409	EFO_0007825

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000164022's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000164022	AIMP1	100	62.821	ENSAPOG00000013539	aimp1	99	60.256	Acanthochromis_polyacanthus
ENSG00000164022	AIMP1	100	85.333	ENSAMEG00000017499	AIMP1	100	88.476	Ailuropoda_melanoleuca
ENSG00000164022	AIMP1	100	62.179	ENSACIG00000020197	aimp1	100	60.436	Amphilophus_citrinellus
ENSG00000164022	AIMP1	53	65.455	ENSACIG00000017258	-	53	65.455	Amphilophus_citrinellus
ENSG00000164022	AIMP1	95	43.771	ENSACIG00000023333	zgc:101853	90	43.087	Amphilophus_citrinellus
ENSG00000164022	AIMP1	97	40.196	ENSAOCG00000018740	-	96	40.439	Amphiprion_ocellaris
ENSG00000164022	AIMP1	59	61.957	ENSAOCG00000014013	-	53	66.258	Amphiprion_ocellaris
ENSG00000164022	AIMP1	100	62.821	ENSAOCG00000020064	aimp1	100	58.876	Amphiprion_ocellaris
ENSG00000164022	AIMP1	59	63.043	ENSAPEG00000011617	-	55	65.868	Amphiprion_percula
ENSG00000164022	AIMP1	100	62.500	ENSAPEG00000014340	aimp1	100	59.271	Amphiprion_percula
ENSG00000164022	AIMP1	95	39.262	ENSAPEG00000018575	zgc:101853	72	40.728	Amphiprion_percula
ENSG00000164022	AIMP1	100	63.407	ENSATEG00000015367	aimp1	100	62.883	Anabas_testudineus
ENSG00000164022	AIMP1	52	70.552	ENSATEG00000013284	-	55	68.639	Anabas_testudineus
ENSG00000164022	AIMP1	98	45.338	ENSATEG00000010419	zgc:101853	96	44.373	Anabas_testudineus
ENSG00000164022	AIMP1	100	74.143	ENSAPLG00000006022	AIMP1	100	76.780	Anas_platyrhynchos
ENSG00000164022	AIMP1	85	90.551	ENSANAG00000033416	AIMP1	99	94.690	Aotus_nancymaae
ENSG00000164022	AIMP1	95	41.751	ENSACLG00000019353	-	98	41.414	Astatotilapia_calliptera
ENSG00000164022	AIMP1	95	41.751	ENSACLG00000018982	zgc:101853	98	41.414	Astatotilapia_calliptera
ENSG00000164022	AIMP1	98	65.909	ENSACLG00000021930	aimp1	96	65.909	Astatotilapia_calliptera
ENSG00000164022	AIMP1	53	67.879	ENSACLG00000024885	-	59	67.879	Astatotilapia_calliptera
ENSG00000164022	AIMP1	100	61.270	ENSAMXG00000019203	aimp1	100	61.398	Astyanax_mexicanus
ENSG00000164022	AIMP1	89	47.368	ENSAMXG00000016160	zgc:101853	93	45.390	Astyanax_mexicanus
ENSG00000164022	AIMP1	100	85.304	ENSBTAG00000004230	AIMP1	100	86.581	Bos_taurus
ENSG00000164022	AIMP1	100	88.667	ENSCJAG00000015885	AIMP1	99	87.778	Callithrix_jacchus
ENSG00000164022	AIMP1	100	84.295	ENSCAFG00000006312	-	100	83.801	Canis_familiaris
ENSG00000164022	AIMP1	100	90.705	ENSCAFG00000011014	-	100	90.343	Canis_familiaris
ENSG00000164022	AIMP1	100	90.064	ENSCAFG00020009990	AIMP1	100	89.720	Canis_lupus_dingo
ENSG00000164022	AIMP1	100	85.897	ENSCHIG00000005492	-	100	85.897	Capra_hircus
ENSG00000164022	AIMP1	100	68.590	ENSCHIG00000022324	-	94	70.154	Capra_hircus
ENSG00000164022	AIMP1	100	86.859	ENSCHIG00000008407	-	100	86.604	Capra_hircus
ENSG00000164022	AIMP1	100	89.423	ENSCHIG00000019094	-	94	88.015	Capra_hircus
ENSG00000164022	AIMP1	100	91.026	ENSTSYG00000013788	AIMP1	100	91.026	Carlito_syrichta
ENSG00000164022	AIMP1	92	79.167	ENSCAPG00000011063	AIMP1	100	79.239	Cavia_aperea
ENSG00000164022	AIMP1	100	79.808	ENSCPOG00000006734	AIMP1	100	80.124	Cavia_porcellus
ENSG00000164022	AIMP1	100	94.231	ENSCCAG00000031943	AIMP1	100	93.146	Cebus_capucinus
ENSG00000164022	AIMP1	100	96.795	ENSCATG00000034569	AIMP1	100	96.885	Cercocebus_atys
ENSG00000164022	AIMP1	100	85.577	ENSCLAG00000003954	AIMP1	100	81.931	Chinchilla_lanigera
ENSG00000164022	AIMP1	100	97.436	ENSCSAG00000003982	AIMP1	79	97.523	Chlorocebus_sabaeus
ENSG00000164022	AIMP1	76	82.773	ENSCHOG00000000619	AIMP1	71	86.555	Choloepus_hoffmanni
ENSG00000164022	AIMP1	100	77.885	ENSCPBG00000004055	AIMP1	100	79.128	Chrysemys_picta_bellii
ENSG00000164022	AIMP1	96	42.368	ENSCING00000021899	-	100	41.033	Ciona_intestinalis
ENSG00000164022	AIMP1	100	97.115	ENSCANG00000037036	AIMP1	100	97.196	Colobus_angolensis_palliatus
ENSG00000164022	AIMP1	100	85.669	ENSCGRG00001012622	Aimp1	100	86.068	Cricetulus_griseus_chok1gshd
ENSG00000164022	AIMP1	71	82.511	ENSCGRG00000014858	Aimp1	99	83.036	Cricetulus_griseus_crigri
ENSG00000164022	AIMP1	100	63.462	ENSCSEG00000002665	aimp1	100	60.802	Cynoglossus_semilaevis
ENSG00000164022	AIMP1	95	42.532	ENSCSEG00000005388	zgc:101853	98	41.946	Cynoglossus_semilaevis
ENSG00000164022	AIMP1	98	65.246	ENSCVAG00000002300	aimp1	100	60.896	Cyprinodon_variegatus
ENSG00000164022	AIMP1	98	42.718	ENSCVAG00000001198	zgc:101853	96	43.450	Cyprinodon_variegatus
ENSG00000164022	AIMP1	95	45.270	ENSDARG00000036894	zgc:101853	83	45.270	Danio_rerio
ENSG00000164022	AIMP1	100	64.127	ENSDARG00000060036	aimp1	100	61.468	Danio_rerio
ENSG00000164022	AIMP1	100	86.306	ENSDNOG00000039310	AIMP1	100	86.378	Dasypus_novemcinctus
ENSG00000164022	AIMP1	100	88.462	ENSDORG00000005018	-	100	87.500	Dipodomys_ordii
ENSG00000164022	AIMP1	99	67.314	ENSDORG00000027118	-	99	66.877	Dipodomys_ordii
ENSG00000164022	AIMP1	98	43.934	FBgn0033351	AIMP1	94	43.711	Drosophila_melanogaster
ENSG00000164022	AIMP1	100	82.051	ENSETEG00000000289	AIMP1	100	82.051	Echinops_telfairi
ENSG00000164022	AIMP1	96	51.495	ENSEBUG00000004401	-	92	51.325	Eptatretus_burgeri
ENSG00000164022	AIMP1	100	75.497	ENSEASG00005013322	-	99	76.250	Equus_asinus_asinus
ENSG00000164022	AIMP1	100	89.103	ENSEASG00005004535	-	100	88.474	Equus_asinus_asinus
ENSG00000164022	AIMP1	100	75.497	ENSECAG00000001942	-	99	76.562	Equus_caballus
ENSG00000164022	AIMP1	100	89.103	ENSECAG00000006138	AIMP1	100	88.889	Equus_caballus
ENSG00000164022	AIMP1	88	80.435	ENSEEUG00000005268	AIMP1	100	85.145	Erinaceus_europaeus
ENSG00000164022	AIMP1	100	58.599	ENSELUG00000016943	aimp1	97	58.896	Esox_lucius
ENSG00000164022	AIMP1	100	88.141	ENSFCAG00000012896	AIMP1	100	87.821	Felis_catus
ENSG00000164022	AIMP1	100	79.808	ENSFALG00000012349	AIMP1	100	82.372	Ficedula_albicollis
ENSG00000164022	AIMP1	100	71.795	ENSFDAG00000011457	-	100	69.470	Fukomys_damarensis
ENSG00000164022	AIMP1	100	84.295	ENSFDAG00000008734	-	100	84.375	Fukomys_damarensis
ENSG00000164022	AIMP1	98	41.214	ENSFHEG00000014117	zgc:101853	91	40.780	Fundulus_heteroclitus
ENSG00000164022	AIMP1	98	61.311	ENSFHEG00000006135	aimp1	98	60.328	Fundulus_heteroclitus
ENSG00000164022	AIMP1	98	61.311	ENSGMOG00000017576	aimp1	100	59.385	Gadus_morhua
ENSG00000164022	AIMP1	100	77.564	ENSGALG00000010553	AIMP1	99	79.872	Gallus_gallus
ENSG00000164022	AIMP1	98	62.295	ENSGAFG00000016039	aimp1	100	60.748	Gambusia_affinis
ENSG00000164022	AIMP1	98	42.258	ENSGAFG00000020220	zgc:101853	100	43.564	Gambusia_affinis
ENSG00000164022	AIMP1	100	61.661	ENSGACG00000017501	aimp1	100	58.407	Gasterosteus_aculeatus
ENSG00000164022	AIMP1	100	75.962	ENSGAGG00000010705	AIMP1	100	75.962	Gopherus_agassizii
ENSG00000164022	AIMP1	100	99.359	ENSGGOG00000004226	AIMP1	100	99.377	Gorilla_gorilla
ENSG00000164022	AIMP1	98	65.584	ENSHBUG00000015770	aimp1	96	65.584	Haplochromis_burtoni
ENSG00000164022	AIMP1	95	43.000	ENSHBUG00000016999	zgc:101853	93	41.613	Haplochromis_burtoni
ENSG00000164022	AIMP1	100	84.615	ENSHGLG00000003860	AIMP1	100	84.424	Heterocephalus_glaber_female
ENSG00000164022	AIMP1	100	84.615	ENSHGLG00100013291	AIMP1	100	84.424	Heterocephalus_glaber_male
ENSG00000164022	AIMP1	63	71.875	ENSHCOG00000000370	zgc:101853	74	71.875	Hippocampus_comes
ENSG00000164022	AIMP1	98	63.666	ENSHCOG00000004278	aimp1	100	61.162	Hippocampus_comes
ENSG00000164022	AIMP1	95	47.386	ENSIPUG00000003203	AIMP1	95	47.712	Ictalurus_punctatus
ENSG00000164022	AIMP1	100	57.500	ENSIPUG00000008314	aimp1	100	57.716	Ictalurus_punctatus
ENSG00000164022	AIMP1	100	88.141	ENSSTOG00000008178	AIMP1	100	90.385	Ictidomys_tridecemlineatus
ENSG00000164022	AIMP1	100	90.385	ENSJJAG00000016873	Aimp1	100	90.385	Jaculus_jaculus
ENSG00000164022	AIMP1	93	43.960	ENSKMAG00000007606	zgc:101853	98	43.289	Kryptolebias_marmoratus
ENSG00000164022	AIMP1	100	64.127	ENSKMAG00000001709	aimp1	100	60.923	Kryptolebias_marmoratus
ENSG00000164022	AIMP1	98	65.246	ENSLBEG00000014734	aimp1	100	58.683	Labrus_bergylta
ENSG00000164022	AIMP1	95	41.967	ENSLBEG00000023802	zgc:101853	93	41.639	Labrus_bergylta
ENSG00000164022	AIMP1	69	57.870	ENSLBEG00000017791	-	55	65.497	Labrus_bergylta
ENSG00000164022	AIMP1	100	70.288	ENSLACG00000010765	AIMP1	100	70.833	Latimeria_chalumnae
ENSG00000164022	AIMP1	100	68.571	ENSLOCG00000012682	aimp1	96	64.110	Lepisosteus_oculatus
ENSG00000164022	AIMP1	88	84.420	ENSLAFG00000012639	AIMP1	100	84.420	Loxodonta_africana
ENSG00000164022	AIMP1	100	96.474	ENSMFAG00000044822	AIMP1	100	96.573	Macaca_fascicularis
ENSG00000164022	AIMP1	100	96.474	ENSMMUG00000015759	AIMP1	100	96.573	Macaca_mulatta
ENSG00000164022	AIMP1	100	96.474	ENSMNEG00000030181	AIMP1	100	96.573	Macaca_nemestrina
ENSG00000164022	AIMP1	100	97.115	ENSMLEG00000040650	AIMP1	100	97.196	Mandrillus_leucophaeus
ENSG00000164022	AIMP1	95	42.140	ENSMAMG00000009716	zgc:101853	93	41.584	Mastacembelus_armatus
ENSG00000164022	AIMP1	100	63.208	ENSMAMG00000015765	aimp1	100	59.767	Mastacembelus_armatus
ENSG00000164022	AIMP1	70	61.468	ENSMAMG00000014617	-	56	70.175	Mastacembelus_armatus
ENSG00000164022	AIMP1	90	42.254	ENSMZEG00005027905	zgc:101853	89	40.816	Maylandia_zebra
ENSG00000164022	AIMP1	98	65.909	ENSMZEG00005019638	aimp1	96	65.909	Maylandia_zebra
ENSG00000164022	AIMP1	52	68.712	ENSMZEG00005009578	-	56	68.485	Maylandia_zebra
ENSG00000164022	AIMP1	100	78.205	ENSMGAG00000005919	AIMP1	98	79.751	Meleagris_gallopavo
ENSG00000164022	AIMP1	100	91.346	ENSMICG00000010202	AIMP1	99	89.877	Microcebus_murinus
ENSG00000164022	AIMP1	100	88.141	ENSMOCG00000001103	-	100	87.539	Microtus_ochrogaster
ENSG00000164022	AIMP1	100	80.449	ENSMOCG00000003749	-	100	80.062	Microtus_ochrogaster
ENSG00000164022	AIMP1	98	62.951	ENSMMOG00000006361	aimp1	100	61.059	Mola_mola
ENSG00000164022	AIMP1	75	51.852	ENSMMOG00000011477	zgc:101853	100	51.852	Mola_mola
ENSG00000164022	AIMP1	69	57.207	ENSMMOG00000005584	-	55	68.263	Mola_mola
ENSG00000164022	AIMP1	100	75.633	ENSMODG00000020613	AIMP1	100	75.385	Monodelphis_domestica
ENSG00000164022	AIMP1	69	61.574	ENSMALG00000001823	-	57	73.810	Monopterus_albus
ENSG00000164022	AIMP1	100	61.342	ENSMALG00000022018	aimp1	100	58.284	Monopterus_albus
ENSG00000164022	AIMP1	95	44.631	ENSMALG00000006471	zgc:101853	95	42.953	Monopterus_albus
ENSG00000164022	AIMP1	100	71.795	MGP_CAROLIEiJ_G0025644	Aimp1	100	70.093	Mus_caroli
ENSG00000164022	AIMP1	100	82.428	ENSMUSG00000028029	Aimp1	100	81.677	Mus_musculus
ENSG00000164022	AIMP1	100	81.789	MGP_PahariEiJ_G0027093	Aimp1	100	80.745	Mus_pahari
ENSG00000164022	AIMP1	100	83.067	MGP_SPRETEiJ_G0026597	Aimp1	100	82.298	Mus_spretus
ENSG00000164022	AIMP1	100	90.064	ENSMPUG00000008952	AIMP1	100	89.720	Mustela_putorius_furo
ENSG00000164022	AIMP1	51	52.381	ENSMPUG00000015208	-	50	52.201	Mustela_putorius_furo
ENSG00000164022	AIMP1	100	90.705	ENSMLUG00000009560	AIMP1	100	90.373	Myotis_lucifugus
ENSG00000164022	AIMP1	95	42.809	ENSNBRG00000024291	zgc:101853	93	39.871	Neolamprologus_brichardi
ENSG00000164022	AIMP1	100	67.093	ENSNBRG00000012670	aimp1	96	66.340	Neolamprologus_brichardi
ENSG00000164022	AIMP1	53	67.879	ENSNBRG00000009760	-	56	67.879	Neolamprologus_brichardi
ENSG00000164022	AIMP1	100	98.077	ENSNLEG00000033706	AIMP1	100	98.131	Nomascus_leucogenys
ENSG00000164022	AIMP1	66	85.965	ENSMEUG00000007107	-	68	84.571	Notamacropus_eugenii
ENSG00000164022	AIMP1	70	96.296	ENSOPRG00000010434	-	83	65.091	Ochotona_princeps
ENSG00000164022	AIMP1	100	82.372	ENSODEG00000008317	-	89	81.056	Octodon_degus
ENSG00000164022	AIMP1	100	82.372	ENSODEG00000010617	-	100	80.997	Octodon_degus
ENSG00000164022	AIMP1	100	64.444	ENSONIG00000017512	aimp1	93	64.444	Oreochromis_niloticus
ENSG00000164022	AIMP1	95	44.000	ENSONIG00000013671	zgc:101853	93	42.857	Oreochromis_niloticus
ENSG00000164022	AIMP1	100	75.478	ENSOANG00000002774	AIMP1	99	74.312	Ornithorhynchus_anatinus
ENSG00000164022	AIMP1	100	90.705	ENSOCUG00000002043	AIMP1	100	90.343	Oryctolagus_cuniculus
ENSG00000164022	AIMP1	98	63.399	ENSORLG00000006773	aimp1	100	60.559	Oryzias_latipes
ENSG00000164022	AIMP1	96	37.423	ENSORLG00000002298	zgc:101853	100	37.423	Oryzias_latipes
ENSG00000164022	AIMP1	98	63.072	ENSORLG00020020644	aimp1	100	59.281	Oryzias_latipes_hni
ENSG00000164022	AIMP1	95	37.624	ENSORLG00020002086	zgc:101853	93	37.624	Oryzias_latipes_hni
ENSG00000164022	AIMP1	95	39.482	ENSORLG00015021117	zgc:101853	100	40.532	Oryzias_latipes_hsok
ENSG00000164022	AIMP1	98	62.418	ENSORLG00015020825	aimp1	100	58.982	Oryzias_latipes_hsok
ENSG00000164022	AIMP1	95	40.924	ENSOMEG00000021489	zgc:101853	93	41.137	Oryzias_melastigma
ENSG00000164022	AIMP1	98	63.279	ENSOMEG00000006090	aimp1	100	59.281	Oryzias_melastigma
ENSG00000164022	AIMP1	88	89.855	ENSOGAG00000002089	AIMP1	100	89.855	Otolemur_garnettii
ENSG00000164022	AIMP1	100	87.821	ENSOARG00000019644	-	100	87.539	Ovis_aries
ENSG00000164022	AIMP1	100	84.345	ENSOARG00000009336	-	100	85.714	Ovis_aries
ENSG00000164022	AIMP1	78	90.625	ENSOARG00000008593	-	100	70.192	Ovis_aries
ENSG00000164022	AIMP1	100	78.914	ENSOARG00000009111	-	99	79.128	Ovis_aries
ENSG00000164022	AIMP1	100	99.359	ENSPPAG00000038355	AIMP1	100	99.377	Pan_paniscus
ENSG00000164022	AIMP1	72	81.333	ENSPPRG00000011212	-	100	81.333	Panthera_pardus
ENSG00000164022	AIMP1	100	83.333	ENSPPRG00000019279	-	95	83.333	Panthera_pardus
ENSG00000164022	AIMP1	100	87.821	ENSPPRG00000003078	-	100	87.500	Panthera_pardus
ENSG00000164022	AIMP1	100	87.500	ENSPTIG00000008163	-	100	87.500	Panthera_tigris_altaica
ENSG00000164022	AIMP1	100	84.295	ENSPTIG00000005433	-	95	83.801	Panthera_tigris_altaica
ENSG00000164022	AIMP1	100	99.038	ENSPTRG00000016345	AIMP1	100	99.065	Pan_troglodytes
ENSG00000164022	AIMP1	100	96.795	ENSPANG00000024758	AIMP1	100	96.885	Papio_anubis
ENSG00000164022	AIMP1	90	51.220	ENSPKIG00000012696	zgc:101853	89	50.523	Paramormyrops_kingsleyae
ENSG00000164022	AIMP1	100	61.859	ENSPKIG00000012660	aimp1	100	61.371	Paramormyrops_kingsleyae
ENSG00000164022	AIMP1	100	76.752	ENSPSIG00000006524	AIMP1	100	75.776	Pelodiscus_sinensis
ENSG00000164022	AIMP1	95	44.108	ENSPMGG00000009140	zgc:101853	100	42.154	Periophthalmus_magnuspinnatus
ENSG00000164022	AIMP1	98	63.399	ENSPMGG00000008272	aimp1	97	61.062	Periophthalmus_magnuspinnatus
ENSG00000164022	AIMP1	100	90.064	ENSPEMG00000003730	Aimp1	100	89.720	Peromyscus_maniculatus_bairdii
ENSG00000164022	AIMP1	100	60.000	ENSPMAG00000008660	aimp1	100	60.241	Petromyzon_marinus
ENSG00000164022	AIMP1	100	76.752	ENSPCIG00000000116	AIMP1	100	80.952	Phascolarctos_cinereus
ENSG00000164022	AIMP1	98	44.201	ENSPFOG00000002610	-	98	43.945	Poecilia_formosa
ENSG00000164022	AIMP1	98	62.951	ENSPFOG00000010749	aimp1	100	61.371	Poecilia_formosa
ENSG00000164022	AIMP1	98	62.623	ENSPLAG00000002895	aimp1	98	62.623	Poecilia_latipinna
ENSG00000164022	AIMP1	94	43.234	ENSPLAG00000004179	zgc:101853	100	43.564	Poecilia_latipinna
ENSG00000164022	AIMP1	98	62.951	ENSPMEG00000018336	aimp1	100	61.371	Poecilia_mexicana
ENSG00000164022	AIMP1	89	44.406	ENSPMEG00000017385	zgc:101853	97	43.299	Poecilia_mexicana
ENSG00000164022	AIMP1	90	40.136	ENSPREG00000014753	zgc:101853	90	40.476	Poecilia_reticulata
ENSG00000164022	AIMP1	98	61.967	ENSPREG00000002704	aimp1	100	60.436	Poecilia_reticulata
ENSG00000164022	AIMP1	100	96.000	ENSPPYG00000014981	AIMP1	92	97.133	Pongo_abelii
ENSG00000164022	AIMP1	62	93.694	ENSPCAG00000015480	-	62	93.694	Procavia_capensis
ENSG00000164022	AIMP1	100	77.564	ENSPCOG00000001426	AIMP1	98	76.947	Propithecus_coquereli
ENSG00000164022	AIMP1	100	90.705	ENSPVAG00000010642	AIMP1	97	90.462	Pteropus_vampyrus
ENSG00000164022	AIMP1	95	42.258	ENSPNYG00000005407	zgc:101853	93	41.290	Pundamilia_nyererei
ENSG00000164022	AIMP1	52	68.098	ENSPNYG00000012011	-	56	67.879	Pundamilia_nyererei
ENSG00000164022	AIMP1	98	65.909	ENSPNYG00000009958	aimp1	96	65.909	Pundamilia_nyererei
ENSG00000164022	AIMP1	100	61.859	ENSPNAG00000022630	aimp1	100	61.371	Pygocentrus_nattereri
ENSG00000164022	AIMP1	54	62.275	ENSPNAG00000003584	zgc:101853	67	62.275	Pygocentrus_nattereri
ENSG00000164022	AIMP1	100	84.936	ENSRNOG00000011384	Aimp1	100	85.670	Rattus_norvegicus
ENSG00000164022	AIMP1	100	97.756	ENSRBIG00000028882	AIMP1	100	97.819	Rhinopithecus_bieti
ENSG00000164022	AIMP1	100	97.333	ENSRROG00000031776	AIMP1	97	98.127	Rhinopithecus_roxellana
ENSG00000164022	AIMP1	100	82.372	ENSSBOG00000035710	AIMP1	100	78.614	Saimiri_boliviensis_boliviensis
ENSG00000164022	AIMP1	100	79.048	ENSSHAG00000000796	AIMP1	100	77.709	Sarcophilus_harrisii
ENSG00000164022	AIMP1	100	59.873	ENSSFOG00015018626	aimp1	100	59.873	Scleropages_formosus
ENSG00000164022	AIMP1	97	54.605	ENSSFOG00015014632	AIMP1	100	54.305	Scleropages_formosus
ENSG00000164022	AIMP1	56	67.045	ENSSMAG00000005210	-	54	68.824	Scophthalmus_maximus
ENSG00000164022	AIMP1	100	63.782	ENSSMAG00000007003	aimp1	100	59.104	Scophthalmus_maximus
ENSG00000164022	AIMP1	95	41.311	ENSSMAG00000017397	-	93	41.720	Scophthalmus_maximus
ENSG00000164022	AIMP1	59	69.399	ENSSDUG00000006723	-	55	68.000	Seriola_dumerili
ENSG00000164022	AIMP1	96	40.461	ENSSDUG00000000194	zgc:101853	98	41.139	Seriola_dumerili
ENSG00000164022	AIMP1	100	63.782	ENSSDUG00000002067	aimp1	100	60.896	Seriola_dumerili
ENSG00000164022	AIMP1	98	64.918	ENSSLDG00000023538	aimp1	100	59.701	Seriola_lalandi_dorsalis
ENSG00000164022	AIMP1	95	43.813	ENSSLDG00000006461	zgc:101853	93	43.813	Seriola_lalandi_dorsalis
ENSG00000164022	AIMP1	59	69.565	ENSSLDG00000025104	-	52	72.393	Seriola_lalandi_dorsalis
ENSG00000164022	AIMP1	100	74.038	ENSSPUG00000006369	AIMP1	100	74.038	Sphenodon_punctatus
ENSG00000164022	AIMP1	100	63.462	ENSSPAG00000001190	aimp1	100	60.896	Stegastes_partitus
ENSG00000164022	AIMP1	59	65.574	ENSSPAG00000002363	-	96	68.235	Stegastes_partitus
ENSG00000164022	AIMP1	100	87.821	ENSSSCG00000024168	AIMP1	100	89.744	Sus_scrofa
ENSG00000164022	AIMP1	100	72.667	ENSTGUG00000003915	AIMP1	100	77.358	Taeniopygia_guttata
ENSG00000164022	AIMP1	98	62.295	ENSTRUG00000007708	aimp1	100	58.160	Takifugu_rubripes
ENSG00000164022	AIMP1	52	47.619	ENSTNIG00000002124	-	76	47.619	Tetraodon_nigroviridis
ENSG00000164022	AIMP1	98	62.215	ENSTNIG00000018027	aimp1	100	56.548	Tetraodon_nigroviridis
ENSG00000164022	AIMP1	100	87.179	ENSTBEG00000004412	AIMP1	100	89.103	Tupaia_belangeri
ENSG00000164022	AIMP1	71	94.595	ENSTTRG00000007791	AIMP1	73	94.595	Tursiops_truncatus
ENSG00000164022	AIMP1	100	91.026	ENSUAMG00000024676	AIMP1	100	90.966	Ursus_americanus
ENSG00000164022	AIMP1	100	90.385	ENSUMAG00000000180	AIMP1	100	90.343	Ursus_maritimus
ENSG00000164022	AIMP1	100	85.623	ENSVPAG00000003941	AIMP1	100	89.720	Vicugna_pacos
ENSG00000164022	AIMP1	100	86.667	ENSVVUG00000017317	AIMP1	100	90.136	Vulpes_vulpes
ENSG00000164022	AIMP1	100	68.371	ENSXETG00000019862	aimp1	100	70.288	Xenopus_tropicalis
ENSG00000164022	AIMP1	98	41.587	ENSXCOG00000013045	zgc:101853	99	40.606	Xiphophorus_couchianus
ENSG00000164022	AIMP1	98	62.623	ENSXMAG00000010255	aimp1	100	60.748	Xiphophorus_maculatus
ENSG00000164022	AIMP1	98	42.598	ENSXMAG00000021224	zgc:101853	96	42.633	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000049	tRNA binding	21873635.	IBA	Function
GO:0000049	tRNA binding	11306575.	IDA	Function
GO:0001525	angiogenesis	-	IEA	Process
GO:0001937	negative regulation of endothelial cell proliferation	11741979.	IDA	Process
GO:0005125	cytokine activity	21873635.	IBA	Function
GO:0005125	cytokine activity	11306575.	ISS	Function
GO:0005515	protein binding	11741979.22190034.24312579.25416956.	IPI	Function
GO:0005615	extracellular space	-	ISS	Component
GO:0005634	nucleus	-	IEA	Component
GO:0005783	endoplasmic reticulum	-	IEA	Component
GO:0005794	Golgi apparatus	-	IEA	Component
GO:0005829	cytosol	19289464.	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006418	tRNA aminoacylation for protein translation	21873635.	IBA	Process
GO:0006418	tRNA aminoacylation for protein translation	-	TAS	Process
GO:0006915	apoptotic process	-	IEA	Process
GO:0006935	chemotaxis	7545917.	TAS	Process
GO:0006954	inflammatory response	-	IEA	Process
GO:0007155	cell adhesion	-	IEA	Process
GO:0007165	signal transduction	9405472.	NAS	Process
GO:0007267	cell-cell signaling	11741979.	IDA	Process
GO:0009611	response to wounding	7545917.	TAS	Process
GO:0009986	cell surface	11741979.	IDA	Component
GO:0010469	regulation of signaling receptor activity	-	IEA	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0017101	aminoacyl-tRNA synthetase multienzyme complex	21873635.	IBA	Component
GO:0017101	aminoacyl-tRNA synthetase multienzyme complex	10791971.14500886.19131329.	IDA	Component
GO:0017102	methionyl glutamyl tRNA synthetase complex	21873635.	IBA	Component
GO:0042803	protein homodimerization activity	11306575.	IDA	Function
GO:0050900	leukocyte migration	11306575.	IDA	Process
GO:0051020	GTPase binding	24337748.	IPI	Function
GO:0051607	defense response to virus	-	IEA	Process
GO:0070094	positive regulation of glucagon secretion	-	ISS	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

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Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

GWAS

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.