EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
25260534	Elevated DDX21 regulates c-Jun activity and rRNA processing in human breast cancers.	Breast Cancer Res	2014 Sep 28	Zhang Y	doi: 10.1186/s13058-014-0449-z.

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr10	68956296	Missense_Mutation	novel	R24Q	0.31
BLCA	chr10	68967066	Missense_Mutation	novel	R318L	0.07	GUCT
BLCA	chr10	68960153	Silent	novel	E145E	0.6
BLCA	chr10	68978969	Missense_Mutation	novel	G677E	0.39
BLCA	chr10	68960114	Silent	NA	K132K	0.21
BLCA	chr10	68971933	Missense_Mutation	NA	E477K	0.48
BLCA	chr10	68978962	Missense_Mutation	NA	L675V	0.17
BLCA	chr10	68973551	Missense_Mutation	NA	E519Q	0.59
BLCA	chr10	68962153	Silent	novel	L201L	0.08
BLCA	chr10	68970276	Missense_Mutation	novel	Q438E	0.36
BRCA	chr10	68977659	Missense_Mutation	rs766890848	D625N	0.28
BRCA	chr10	68977655	Silent	rs751106704	S623S	0.17
BRCA	chr10	68969046	Missense_Mutation	novel	K387N	0.07
BRCA	chr10	68969094	Missense_Mutation	NA	K403N	0.29
BRCA	chr10	68960244	Missense_Mutation	novel	E176Q	0.11
BRCA	chr10	68969010	Frame_Shift_Ins	novel	*A376Hfs10**	0.14	GUCT
BRCA	chr10	68969011	Frame_Shift_Ins	novel	*A376Gfs26**	0.14	GUCT
BRCA	chr10	68977542	Missense_Mutation	NA	V586M	0.25
BRCA	chr10	68963375	Missense_Mutation	NA	R231Q	0.1	GUCT
BRCA	chr10	68977570	Missense_Mutation	NA	K595R	0.23
CESC	chr10	68960120	Silent	NA	K134K	0.48
CESC	chr10	68956184	5'UTR	novel		0.63
CESC	chr10	68965430	Silent	novel	F280F	0.11
CESC	chr10	68978872	Missense_Mutation	rs201054642	I645V	0.35
CESC	chr10	68962108	Silent	rs773004828	G186G	0.35
CESC	chr10	68977656	Missense_Mutation	rs754549618	V624I	0.48
CESC	chr10	68956140	5'UTR	novel		0.32
CESC	chr10	68978929	Missense_Mutation	NA	E664Q	0.57
COAD	chr10	68967023	Missense_Mutation	rs144769035	R304C	0.51	GUCT
COAD	chr10	68982671	Silent	novel	Q737Q	0.13
COAD	chr10	68970219	Missense_Mutation	NA	H419N	0.2
COAD	chr10	68982784	Missense_Mutation	rs200756197	R775Q	0.22
COAD	chr10	68967056	Missense_Mutation	novel	T315S	0.06	GUCT
COAD	chr10	68960063	Frame_Shift_Del	NA	*N117Mfs9**	0.26
COAD	chr10	68962140	Frame_Shift_Ins	novel	*I198Hfs12**	0.07
COAD	chr10	68982677	Silent	rs746814470	D739D	0.32
COAD	chr10	68969088	Silent	novel	G401G	0.31
COAD	chr10	68969019	Silent	NA	C378C	0.23
ESCA	chr10	68974686	Missense_Mutation	novel	R562P	0.09
ESCA	chr10	68956296	Missense_Mutation	novel	R24P	0.31
GBM	chr10	68963357	Missense_Mutation	novel	D225G	0.06	GUCT
HNSC	chr10	68969105	Missense_Mutation	novel	T407M	0.11
HNSC	chr10	68977644	Frame_Shift_Del	novel	*G620Vfs5**	0.49
HNSC	chr10	68960215	Missense_Mutation	novel	A166V	0.07
HNSC	chr10	68981561	Missense_Mutation	rs771949249	A688T	0.21
HNSC	chr10	68969058	Silent	novel	K391K	0.4
HNSC	chr10	68977581	Missense_Mutation	novel	E599K	0.13
KIRC	chr10	68982773	Missense_Mutation	NA	K771N	0.32
KIRC	chr10	68973625	Missense_Mutation	NA	H543Q	0.04
KIRP	chr10	68974732	Missense_Mutation	novel	K577N	0.24
LGG	chr10	68963375	Missense_Mutation	NA	R231Q	0.36	GUCT
LGG	chr10	68978889	Silent	novel	I650I	0.12
LIHC	chr10	68956138	5'UTR	novel		0.05
LIHC	chr10	68970334	Missense_Mutation	NA	N457I	0.16
LIHC	chr10	68960003	Silent	novel	L95L	0.42
LUAD	chr10	68973577	Silent	NA	R527R	0.1
LUAD	chr10	68981552	Missense_Mutation	NA	V685L	0.16
LUAD	chr10	68963294	Missense_Mutation	rs758978836	R204Q	0.2
LUAD	chr10	68967168	Missense_Mutation	novel	Q352L	0.83	GUCT
LUAD	chr10	68959986	Missense_Mutation	novel	P90A	0.31
LUAD	chr10	68969122	Splice_Site	novel	X412_splice	0.19
LUSC	chr10	68960114	Silent	NA	K132K	0.23
LUSC	chr10	68974669	Splice_Site	novel	X557_splice	0.19
LUSC	chr10	68960144	Missense_Mutation	novel	E142D	0.47
OV	chr10	68970317	Frame_Shift_Del	novel	*Q452Pfs6**	0.1
OV	chr10	68962124	Missense_Mutation	NA	P192T	0.14
OV	chr10	68978848	Frame_Shift_Del	novel	V637*	0.26
PCPG	chr10	68973563	Missense_Mutation	novel	H523Y	0.08
READ	chr10	68960011	Missense_Mutation	novel	K98T	0.49
READ	chr10	68978956	Missense_Mutation	novel	V673F	0.43
SARC	chr10	68959933	Missense_Mutation	novel	P72L	0.16
SARC	chr10	68959932	Missense_Mutation	rs374486646	P72S	0.2
SARC	chr10	68969122	Splice_Site	novel	X412_splice	0.1
SKCM	chr10	68974697	Missense_Mutation	novel	P566S	0.32
SKCM	chr10	68974698	Missense_Mutation	novel	P566L	0.33
SKCM	chr10	68970219	Missense_Mutation	novel	H419Y	0.38
SKCM	chr10	68982608	Silent	NA	G716G	0.27
SKCM	chr10	68956172	5'UTR	novel		0.25
SKCM	chr10	68970340	Missense_Mutation	novel	A459V	0.43
SKCM	chr10	68970257	Silent	NA	I431I	0.1
SKCM	chr10	68977654	Missense_Mutation	NA	S623F	0.26
SKCM	chr10	68956172	5'UTR	novel		0.5
SKCM	chr10	68960183	Silent	NA	P155P	0.54
STAD	chr10	68956282	Silent	NA	K19K	0.18
STAD	chr10	68973554	Missense_Mutation	NA	S520A	0.16
STAD	chr10	68970282	Missense_Mutation	rs766854373	R440C	0.38
STAD	chr10	68959811	Frame_Shift_Ins	novel	*E34Rfs6**	0.19
STAD	chr10	68973598	Frame_Shift_Del	novel	*V536Cfs14**	0.29
STAD	chr10	68971918	Missense_Mutation	novel	P472S	0.3
STAD	chr10	68963404	Missense_Mutation	NA	A241T	0.28	GUCT
UCEC	chr10	68982779	Missense_Mutation	novel	Q773H	0.26
UCEC	chr10	68963292	Splice_Region	novel	G203G	0.57
UCEC	chr10	68956292	Missense_Mutation	NA	L23V	0.14
UCEC	chr10	68960127	Missense_Mutation	novel	K137Q	0.31
UCEC	chr10	68982965	3'UTR	novel		0.13
UCEC	chr10	68982967	3'UTR	novel		0.13
UCEC	chr10	68982565	Missense_Mutation	novel	R702H	0.34
UCEC	chr10	68962108	Silent	rs773004828	G186G	0.33
UCEC	chr10	68963457	Silent	rs201972394	G258G	0.51
UCEC	chr10	68960088	Missense_Mutation	NA	E124K	0.22
UCEC	chr10	68969107	Missense_Mutation	NA	A408T	0.45
UCEC	chr10	68978925	Silent	novel	G662G	0.17
UCEC	chr10	68963453	Missense_Mutation	novel	R257I	0.57	GUCT
UCEC	chr10	68982842	3'UTR	novel		0.55
UCEC	chr10	68960173	Missense_Mutation	novel	N152S	0.5
UCEC	chr10	68971894	Missense_Mutation	novel	A464S	0.52
UCEC	chr10	68981561	Missense_Mutation	rs771949249	A688T	0.31
UCEC	chr10	68971955	Missense_Mutation	novel	R484I	0.3
UCEC	chr10	68982673	Missense_Mutation	rs780127993	R738Q	0.23
UCEC	chr10	68978956	Missense_Mutation	novel	V673F	0.48
UCEC	chr10	68977656	Missense_Mutation	rs754549618	V624I	0.41
UCEC	chr10	68967157	Silent	novel	G348G	0.12
UCEC	chr10	68978951	Missense_Mutation	novel	G671E	0.17
UCEC	chr10	68982688	Missense_Mutation	novel	R743I	0.08
UCEC	chr10	68963297	Missense_Mutation	novel	G205E	0.23
UCEC	chr10	68982733	Missense_Mutation	novel	R758Q	0.66
UCEC	chr10	68965419	Missense_Mutation	novel	S277R	0.34	GUCT
UCEC	chr10	68960098	Missense_Mutation	NA	A127V	0.16
UCEC	chr10	68963400	Silent	NA	S239S	0.35
UCEC	chr10	68971971	Silent	novel	G489G	0.24
UCEC	chr10	68970283	Missense_Mutation	rs201590875	R440H	0.32
UCEC	chr10	68963447	Missense_Mutation	novel	R255M	0.4	GUCT
UCEC	chr10	68973576	Missense_Mutation	novel	R527Q	0.13
UCEC	chr10	68959863	Nonsense_Mutation	NA	E49*	0.44
UCEC	chr10	68978905	Nonsense_Mutation	novel	E656*	0.06
UCEC	chr10	68981548	Missense_Mutation	novel	F683L	0.38
UCEC	chr10	68982825	3'UTR	novel		0.36
UCEC	chr10	68960160	Missense_Mutation	novel	P148T	0.16
UCEC	chr10	68967024	Missense_Mutation	novel	R304H	0.43	GUCT
UCEC	chr10	68969073	Missense_Mutation	novel	Q396H	0.18
UCEC	chr10	68971895	Missense_Mutation	novel	A464D	0.23
UCEC	chr10	68971994	Missense_Mutation	novel	A497D	0.25
UCEC	chr10	68982613	Missense_Mutation	novel	R718L	0.11
UCEC	chr10	68982864	3'UTR	novel		0.27
UCEC	chr10	68974672	Splice_Region	NA	G557G	0.26
UCEC	chr10	68978931	Silent	novel	E664E	0.36
UCEC	chr10	68982733	Missense_Mutation	novel	R758Q	0.33

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	DEL	0.1111	0.19593
ESCA	DEL	0.1902	0.039099
THCA	DEL	0.022	0.011063

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0062	Kaplan-Meier Survival Analysis
SARC	0.0092	Kaplan-Meier Survival Analysis
MESO	0.00016	Kaplan-Meier Survival Analysis
ACC	0.00022	Kaplan-Meier Survival Analysis
HNSC	0.012	Kaplan-Meier Survival Analysis
KIRP	0.00012	Kaplan-Meier Survival Analysis
COAD	0.038	Kaplan-Meier Survival Analysis
PAAD	0.00061	Kaplan-Meier Survival Analysis
BLCA	0.013	Kaplan-Meier Survival Analysis
CESC	0.011	Kaplan-Meier Survival Analysis
READ	0.033	Kaplan-Meier Survival Analysis
UCEC	0.048	Kaplan-Meier Survival Analysis
GBM	0.048	Kaplan-Meier Survival Analysis
LIHC	0.013	Kaplan-Meier Survival Analysis
LGG	0.0017	Kaplan-Meier Survival Analysis
LUAD	0.0023	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

PRI

Literatures

Expression

Transcripts

Gene Model

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000165732 (Gene tree)
Gene ID: 9188
Gene Symbol: DDX21
Alias: RH-II/GU|GURDB
Full Name: DExD-box helicase 21
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 28,951 bases
Position: chr10:68,956,123-68,985,073
Accession: 2744
RBP type: canonical RBP
Summary: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000480334	GUCT	PF08152.12	7.3e-31	1	1
ENSP00000346120	GUCT	PF08152.12	7.8e-31	1	1
ENSP00000480334	ResIII	PF04851.15	3.1e-08	1	1
ENSP00000346120	ResIII	PF04851.15	3.8e-08	1	1
ENSP00000480334	DEAD	PF00270.29	1.1e-46	1	1
ENSP00000346120	DEAD	PF00270.29	1.2e-46	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	NascentRICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Protein-RNA interaction（RNA-Binding Site）

Click here to download all RNA binding sites

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
11029582	Structural domains involved in the RNA folding activity of RNA helicase II/Gu protein.	Eur J Biochem	2000 Nov	Valdez BC	-
24721576	Cellular DDX21 RNA helicase inhibits influenza A virus replication but is counteracted by the viral NS1 protein.	Cell Host Microbe	2014 Apr 9	Chen G	doi: 10.1016/j.chom.2014.03.002.
16603771	The WSTF-SNF2h chromatin remodeling complex interacts with several nuclear proteins in transcription.	J Biol Chem	2006 Jun 16	Cavellan E	-
10600508	Adriamycin inhibits human RH II/Gu RNA helicase activity by binding to its substrate.	Biochem Biophys Res Commun	1999 Dec 20	Zhu K	-
21703541	DDX1, DDX21, and DHX36 helicases form a complex with the adaptor molecule TRIF to sense dsRNA in dendritic cells.	Immunity	2011 Jun 24	Zhang Z	doi: 10.1016/j.immuni.2011.03.027.
28472472	Human DDX21 binds and unwinds RNA guanine quadruplexes.	Nucleic Acids Res	2017 Jun 20	McRae EKS	doi: 10.1093/nar/gkx380.

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000620315	DDX21-202	4829	XM_017016910	ENSP00000480334	715 (aa)	XP_016872399	Q9NR30
ENST00000354185	DDX21-201	4711	XM_011540336	ENSP00000346120	783 (aa)	XP_011538638	Q9NR30

Gene Model

Click here to download ENSG00000165732's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000165732's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000165732	DDX21	56	32.688	ENSG00000213782	DDX47	86	32.688
ENSG00000165732	DDX21	51	32.976	ENSG00000156976	EIF4A2	90	32.464
ENSG00000165732	DDX21	52	30.348	ENSG00000111364	DDX55	92	35.196
ENSG00000165732	DDX21	51	32.620	ENSG00000141543	EIF4A3	91	32.316
ENSG00000165732	DDX21	55	30.414	ENSG00000183258	DDX41	61	30.562
ENSG00000165732	DDX21	50	36.240	ENSG00000080007	DDX43	54	36.240
ENSG00000165732	DDX21	84	65.372	ENSG00000107625	DDX50	93	62.536
ENSG00000165732	DDX21	60	31.416	ENSG00000215301	DDX3X	72	34.648
ENSG00000165732	DDX21	51	33.155	ENSG00000161960	EIF4A1	99	35.928
ENSG00000165732	DDX21	51	30.263	ENSG00000157349	DDX19B	94	30.541
ENSG00000165732	DDX21	51	35.027	ENSG00000178105	DDX10	53	35.027
ENSG00000165732	DDX21	51	30.526	ENSG00000168872	DDX19A	88	30.811
ENSG00000165732	DDX21	56	32.297	ENSG00000088205	DDX18	81	32.836
ENSG00000165732	DDX21	50	33.602	ENSG00000198231	DDX42	50	33.602
ENSG00000165732	DDX21	57	32.360	ENSG00000067048	DDX3Y	65	32.426
ENSG00000165732	DDX21	51	32.065	ENSG00000184735	DDX53	57	32.065
ENSG00000165732	DDX21	51	33.952	ENSG00000100201	DDX17	50	34.218
ENSG00000165732	DDX21	52	32.723	ENSG00000124228	DDX27	84	30.738

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000165732	DDX21	52	77.867	ENSAPOG00000012269	ddx21	74	74.442	Acanthochromis_polyacanthus
ENSG00000165732	DDX21	100	82.992	ENSAMEG00000017978	DDX21	100	81.669	Ailuropoda_melanoleuca
ENSG00000165732	DDX21	77	74.955	ENSACIG00000006429	ddx21	84	70.440	Amphilophus_citrinellus
ENSG00000165732	DDX21	85	68.914	ENSAOCG00000023174	ddx21	82	69.497	Amphiprion_ocellaris
ENSG00000165732	DDX21	85	68.914	ENSAPEG00000007108	ddx21	82	69.497	Amphiprion_percula
ENSG00000165732	DDX21	77	73.455	ENSATEG00000022194	ddx21	84	69.688	Anabas_testudineus
ENSG00000165732	DDX21	85	70.673	ENSAPLG00000013022	-	94	69.254	Anas_platyrhynchos
ENSG00000165732	DDX21	89	71.880	ENSACAG00000009829	DDX21	79	71.880	Anolis_carolinensis
ENSG00000165732	DDX21	100	97.762	ENSANAG00000038109	DDX21	100	96.807	Aotus_nancymaae
ENSG00000165732	DDX21	77	73.636	ENSACLG00000008248	ddx21	79	68.917	Astatotilapia_calliptera
ENSG00000165732	DDX21	77	73.540	ENSAMXG00000009140	ddx21	86	68.489	Astyanax_mexicanus
ENSG00000165732	DDX21	100	88.662	ENSBTAG00000014558	DDX21	100	88.662	Bos_taurus
ENSG00000165732	DDX21	100	96.923	ENSCJAG00000012876	DDX21	100	95.913	Callithrix_jacchus
ENSG00000165732	DDX21	100	91.353	ENSCAFG00000013791	DDX21	100	89.186	Canis_familiaris
ENSG00000165732	DDX21	100	90.642	ENSCHIG00000000248	-	99	88.667	Capra_hircus
ENSG00000165732	DDX21	100	66.624	ENSCHIG00000014104	-	92	67.006	Capra_hircus
ENSG00000165732	DDX21	100	61.958	ENSCHIG00000006053	-	91	59.722	Capra_hircus
ENSG00000165732	DDX21	100	89.158	ENSTSYG00000011231	DDX21	100	90.179	Carlito_syrichta
ENSG00000165732	DDX21	90	75.045	ENSCAPG00000005945	DDX21	94	66.259	Cavia_aperea
ENSG00000165732	DDX21	98	87.518	ENSCPOG00000015479	DDX21	100	86.497	Cavia_porcellus
ENSG00000165732	DDX21	100	97.343	ENSCCAG00000026288	DDX21	100	96.296	Cebus_capucinus
ENSG00000165732	DDX21	100	97.762	ENSCATG00000043540	DDX21	100	97.573	Cercocebus_atys
ENSG00000165732	DDX21	100	76.756	ENSCATG00000045019	-	100	76.756	Cercocebus_atys
ENSG00000165732	DDX21	100	87.172	ENSCLAG00000012235	DDX21	100	86.497	Chinchilla_lanigera
ENSG00000165732	DDX21	100	79.190	ENSCHOG00000000234	DDX21	100	78.344	Choloepus_hoffmanni
ENSG00000165732	DDX21	94	70.606	ENSCPBG00000019934	-	89	72.403	Chrysemys_picta_bellii
ENSG00000165732	DDX21	90	72.798	ENSCPBG00000019937	-	76	73.209	Chrysemys_picta_bellii
ENSG00000165732	DDX21	100	98.322	ENSCANG00000039926	DDX21	100	97.573	Colobus_angolensis_palliatus
ENSG00000165732	DDX21	100	77.902	ENSCANG00000036110	-	100	77.395	Colobus_angolensis_palliatus
ENSG00000165732	DDX21	100	75.314	ENSCGRG00001017824	-	100	72.611	Cricetulus_griseus_chok1gshd
ENSG00000165732	DDX21	99	85.035	ENSCGRG00001016264	-	99	81.633	Cricetulus_griseus_chok1gshd
ENSG00000165732	DDX21	99	85.035	ENSCGRG00000015134	-	99	81.633	Cricetulus_griseus_crigri
ENSG00000165732	DDX21	100	75.453	ENSCGRG00000008450	-	100	72.739	Cricetulus_griseus_crigri
ENSG00000165732	DDX21	83	68.456	ENSCSEG00000013939	ddx21	82	68.254	Cynoglossus_semilaevis
ENSG00000165732	DDX21	76	73.148	ENSCVAG00000018333	ddx21	83	67.241	Cyprinodon_variegatus
ENSG00000165732	DDX21	77	74.182	ENSDARG00000063626	ddx21	79	69.654	Danio_rerio
ENSG00000165732	DDX21	99	87.328	ENSDNOG00000001680	DDX21	99	85.789	Dasypus_novemcinctus
ENSG00000165732	DDX21	100	79.323	ENSDORG00000002202	Ddx21	100	81.091	Dipodomys_ordii
ENSG00000165732	DDX21	100	85.793	ENSETEG00000014073	DDX21	100	85.246	Echinops_telfairi
ENSG00000165732	DDX21	100	89.118	ENSEASG00005015598	DDX21	100	87.799	Equus_asinus_asinus
ENSG00000165732	DDX21	100	90.922	ENSECAG00000010810	DDX21	100	89.045	Equus_caballus
ENSG00000165732	DDX21	89	79.256	ENSEEUG00000005959	DDX21	100	78.910	Erinaceus_europaeus
ENSG00000165732	DDX21	84	66.285	ENSELUG00000018856	ddx21	80	70.370	Esox_lucius
ENSG00000165732	DDX21	100	92.318	ENSFCAG00000002109	DDX21	100	90.318	Felis_catus
ENSG00000165732	DDX21	75	72.643	ENSFALG00000013043	-	85	68.833	Ficedula_albicollis
ENSG00000165732	DDX21	75	77.737	ENSFALG00000013022	-	96	69.896	Ficedula_albicollis
ENSG00000165732	DDX21	100	89.525	ENSFDAG00000007401	DDX21	100	87.898	Fukomys_damarensis
ENSG00000165732	DDX21	82	69.388	ENSFHEG00000019089	ddx21	81	68.612	Fundulus_heteroclitus
ENSG00000165732	DDX21	75	67.290	ENSGMOG00000012354	ddx21	99	63.502	Gadus_morhua
ENSG00000165732	DDX21	84	69.787	ENSGALG00000042254	-	84	73.063	Gallus_gallus
ENSG00000165732	DDX21	91	68.175	ENSGALG00000004144	-	95	68.304	Gallus_gallus
ENSG00000165732	DDX21	82	69.506	ENSGAFG00000003427	ddx21	83	67.829	Gambusia_affinis
ENSG00000165732	DDX21	83	69.115	ENSGACG00000016060	ddx21	95	68.487	Gasterosteus_aculeatus
ENSG00000165732	DDX21	86	73.203	ENSGAGG00000022169	-	87	71.787	Gopherus_agassizii
ENSG00000165732	DDX21	95	69.546	ENSGAGG00000022163	-	85	70.299	Gopherus_agassizii
ENSG00000165732	DDX21	100	99.720	ENSGGOG00000005065	DDX21	100	99.617	Gorilla_gorilla
ENSG00000165732	DDX21	77	73.636	ENSHBUG00000017638	ddx21	79	68.770	Haplochromis_burtoni
ENSG00000165732	DDX21	100	87.291	ENSHGLG00000013902	DDX21	100	87.516	Heterocephalus_glaber_female
ENSG00000165732	DDX21	100	87.291	ENSHGLG00100015956	DDX21	100	87.516	Heterocephalus_glaber_male
ENSG00000165732	DDX21	81	70.588	ENSHCOG00000014503	ddx21	86	68.025	Hippocampus_comes
ENSG00000165732	DDX21	77	74.141	ENSIPUG00000006972	ddx21	80	69.726	Ictalurus_punctatus
ENSG00000165732	DDX21	99	89.409	ENSSTOG00000011572	DDX21	100	87.829	Ictidomys_tridecemlineatus
ENSG00000165732	DDX21	100	82.650	ENSJJAG00000014035	Ddx21	100	80.476	Jaculus_jaculus
ENSG00000165732	DDX21	77	71.429	ENSKMAG00000020766	ddx21	82	67.886	Kryptolebias_marmoratus
ENSG00000165732	DDX21	85	68.144	ENSLBEG00000001244	ddx21	82	68.304	Labrus_bergylta
ENSG00000165732	DDX21	84	71.993	ENSLACG00000000658	DDX21	99	72.533	Latimeria_chalumnae
ENSG00000165732	DDX21	75	75.696	ENSLOCG00000009123	ddx21	79	70.968	Lepisosteus_oculatus
ENSG00000165732	DDX21	100	87.326	ENSLAFG00000007962	DDX21	100	87.294	Loxodonta_africana
ENSG00000165732	DDX21	100	76.433	ENSMFAG00000033536	-	100	76.433	Macaca_fascicularis
ENSG00000165732	DDX21	100	97.902	ENSMFAG00000044838	DDX21	100	97.701	Macaca_fascicularis
ENSG00000165732	DDX21	100	79.490	ENSMMUG00000032331	-	100	80.510	Macaca_mulatta
ENSG00000165732	DDX21	100	97.902	ENSMMUG00000001005	DDX21	100	97.701	Macaca_mulatta
ENSG00000165732	DDX21	100	98.042	ENSMNEG00000032825	DDX21	100	97.701	Macaca_nemestrina
ENSG00000165732	DDX21	100	76.884	ENSMLEG00000028215	-	100	76.884	Mandrillus_leucophaeus
ENSG00000165732	DDX21	100	94.266	ENSMLEG00000028940	DDX21	100	94.125	Mandrillus_leucophaeus
ENSG00000165732	DDX21	94	64.636	ENSMAMG00000019683	ddx21	86	67.302	Mastacembelus_armatus
ENSG00000165732	DDX21	77	73.636	ENSMZEG00005011618	ddx21	84	68.917	Maylandia_zebra
ENSG00000165732	DDX21	82	73.737	ENSMGAG00000004298	DDX21	98	69.896	Meleagris_gallopavo
ENSG00000165732	DDX21	100	84.777	ENSMAUG00000011153	Ddx21	95	84.626	Mesocricetus_auratus
ENSG00000165732	DDX21	100	89.668	ENSMICG00000015112	-	100	89.923	Microcebus_murinus
ENSG00000165732	DDX21	100	81.259	ENSMICG00000033371	-	100	80.995	Microcebus_murinus
ENSG00000165732	DDX21	98	86.421	ENSMOCG00000020855	Ddx21	100	82.952	Microtus_ochrogaster
ENSG00000165732	DDX21	67	73.444	ENSMMOG00000015938	ddx21	91	73.444	Mola_mola
ENSG00000165732	DDX21	91	70.839	ENSMODG00000010727	DDX21	100	69.168	Monodelphis_domestica
ENSG00000165732	DDX21	81	68.566	ENSMALG00000010489	ddx21	94	65.971	Monopterus_albus
ENSG00000165732	DDX21	100	84.840	MGP_CAROLIEiJ_G0015388	Ddx21	100	81.830	Mus_caroli
ENSG00000165732	DDX21	100	88.490	ENSMUSG00000020075	Ddx21	99	88.490	Mus_musculus
ENSG00000165732	DDX21	100	88.490	MGP_SPRETEiJ_G0016199	Ddx21	96	88.490	Mus_spretus
ENSG00000165732	DDX21	98	91.243	ENSMPUG00000004603	DDX21	100	88.931	Mustela_putorius_furo
ENSG00000165732	DDX21	99	82.979	ENSMLUG00000023298	DDX21	99	84.088	Myotis_lucifugus
ENSG00000165732	DDX21	100	85.185	ENSNGAG00000022273	Ddx21	100	84.557	Nannospalax_galili
ENSG00000165732	DDX21	77	73.636	ENSNBRG00000006198	ddx21	84	69.025	Neolamprologus_brichardi
ENSG00000165732	DDX21	100	99.161	ENSNLEG00000011591	DDX21	100	99.161	Nomascus_leucogenys
ENSG00000165732	DDX21	52	71.850	ENSMEUG00000010586	-	61	73.867	Notamacropus_eugenii
ENSG00000165732	DDX21	92	79.363	ENSOPRG00000001640	DDX21	100	79.226	Ochotona_princeps
ENSG00000165732	DDX21	92	70.483	ENSODEG00000012879	-	99	70.483	Octodon_degus
ENSG00000165732	DDX21	77	73.455	ENSONIG00000005499	ddx21	79	68.819	Oreochromis_niloticus
ENSG00000165732	DDX21	94	70.370	ENSOANG00000004777	DDX21	99	65.872	Ornithorhynchus_anatinus
ENSG00000165732	DDX21	97	89.375	ENSOCUG00000002888	DDX21	97	89.375	Oryctolagus_cuniculus
ENSG00000165732	DDX21	91	66.104	ENSORLG00000010122	ddx21	96	68.612	Oryzias_latipes
ENSG00000165732	DDX21	91	65.798	ENSORLG00020004409	ddx21	95	68.246	Oryzias_latipes_hni
ENSG00000165732	DDX21	91	65.951	ENSORLG00015000051	ddx21	96	68.612	Oryzias_latipes_hsok
ENSG00000165732	DDX21	87	68.539	ENSOMEG00000004523	ddx21	80	68.680	Oryzias_melastigma
ENSG00000165732	DDX21	100	76.862	ENSOGAG00000001846	-	91	91.107	Otolemur_garnettii
ENSG00000165732	DDX21	86	83.721	ENSOGAG00000031242	-	98	82.680	Otolemur_garnettii
ENSG00000165732	DDX21	100	90.922	ENSOARG00000005307	DDX21	100	88.153	Ovis_aries
ENSG00000165732	DDX21	100	99.745	ENSPPAG00000036670	DDX21	100	99.745	Pan_paniscus
ENSG00000165732	DDX21	100	92.318	ENSPPRG00000012523	DDX21	100	90.318	Panthera_pardus
ENSG00000165732	DDX21	100	92.039	ENSPTIG00000007268	DDX21	100	89.936	Panthera_tigris_altaica
ENSG00000165732	DDX21	100	99.872	ENSPTRG00000002563	DDX21	100	99.872	Pan_troglodytes
ENSG00000165732	DDX21	100	97.902	ENSPANG00000022140	DDX21	100	97.701	Papio_anubis
ENSG00000165732	DDX21	100	76.373	ENSPANG00000031334	-	100	76.373	Papio_anubis
ENSG00000165732	DDX21	93	63.291	ENSPKIG00000014660	ddx21	85	69.401	Paramormyrops_kingsleyae
ENSG00000165732	DDX21	93	70.772	ENSPSIG00000004724	DDX21	93	71.166	Pelodiscus_sinensis
ENSG00000165732	DDX21	100	85.832	ENSPEMG00000018513	Ddx21	100	85.260	Peromyscus_maniculatus_bairdii
ENSG00000165732	DDX21	99	70.067	ENSPCIG00000015505	DDX21	99	69.191	Phascolarctos_cinereus
ENSG00000165732	DDX21	82	69.847	ENSPFOG00000016196	ddx21	77	68.463	Poecilia_formosa
ENSG00000165732	DDX21	74	71.940	ENSPLAG00000017849	ddx21	85	68.220	Poecilia_latipinna
ENSG00000165732	DDX21	82	69.847	ENSPMEG00000014571	ddx21	77	68.463	Poecilia_mexicana
ENSG00000165732	DDX21	100	99.301	ENSPPYG00000002389	DDX21	100	99.234	Pongo_abelii
ENSG00000165732	DDX21	88	85.008	ENSPCAG00000016697	DDX21	100	83.190	Procavia_capensis
ENSG00000165732	DDX21	100	86.607	ENSPCOG00000019284	DDX21	100	87.245	Propithecus_coquereli
ENSG00000165732	DDX21	100	92.469	ENSPVAG00000009521	DDX21	100	90.585	Pteropus_vampyrus
ENSG00000165732	DDX21	73	74.046	ENSPNYG00000015566	ddx21	99	67.680	Pundamilia_nyererei
ENSG00000165732	DDX21	81	68.631	ENSPNAG00000004814	ddx21	79	70.766	Pygocentrus_nattereri
ENSG00000165732	DDX21	99	87.273	ENSRNOG00000048990	AABR07037356.1	100	83.969	Rattus_norvegicus
ENSG00000165732	DDX21	99	87.832	ENSRNOG00000043099	Ddx21	100	84.097	Rattus_norvegicus
ENSG00000165732	DDX21	100	89.017	ENSRBIG00000035862	-	100	88.889	Rhinopithecus_bieti
ENSG00000165732	DDX21	100	98.462	ENSRBIG00000043721	-	100	97.829	Rhinopithecus_bieti
ENSG00000165732	DDX21	100	98.322	ENSRROG00000033387	DDX21	100	97.701	Rhinopithecus_roxellana
ENSG00000165732	DDX21	99	71.627	ENSSBOG00000025801	-	100	70.332	Saimiri_boliviensis_boliviensis
ENSG00000165732	DDX21	88	68.621	ENSSFOG00015014610	ddx21	97	69.025	Scleropages_formosus
ENSG00000165732	DDX21	75	73.458	ENSSMAG00000003932	ddx21	82	68.254	Scophthalmus_maximus
ENSG00000165732	DDX21	78	72.482	ENSSDUG00000021420	ddx21	83	69.291	Seriola_dumerili
ENSG00000165732	DDX21	77	72.333	ENSSLDG00000025665	ddx21	97	69.489	Seriola_lalandi_dorsalis
ENSG00000165732	DDX21	66	76.119	ENSSARG00000014024	-	69	74.324	Sorex_araneus
ENSG00000165732	DDX21	85	75.286	ENSSPUG00000004088	DDX21	83	75.817	Sphenodon_punctatus
ENSG00000165732	DDX21	76	73.333	ENSSPAG00000013142	ddx21	83	68.711	Stegastes_partitus
ENSG00000165732	DDX21	100	88.010	ENSSSCG00000010247	DDX21	100	88.010	Sus_scrofa
ENSG00000165732	DDX21	75	79.737	ENSTGUG00000003810	-	88	74.068	Taeniopygia_guttata
ENSG00000165732	DDX21	76	74.815	ENSTRUG00000017570	ddx21	82	71.005	Takifugu_rubripes
ENSG00000165732	DDX21	84	69.486	ENSTNIG00000013798	ddx21	100	68.571	Tetraodon_nigroviridis
ENSG00000165732	DDX21	100	78.599	ENSTBEG00000002310	DDX21	100	78.854	Tupaia_belangeri
ENSG00000165732	DDX21	100	88.153	ENSTTRG00000016398	DDX21	100	88.153	Tursiops_truncatus
ENSG00000165732	DDX21	100	91.586	ENSUMAG00000007735	DDX21	100	89.421	Ursus_maritimus
ENSG00000165732	DDX21	85	91.326	ENSVPAG00000000627	DDX21	99	89.265	Vicugna_pacos
ENSG00000165732	DDX21	100	90.358	ENSVVUG00000020486	DDX21	100	88.413	Vulpes_vulpes
ENSG00000165732	DDX21	74	71.375	ENSXCOG00000009654	ddx21	82	67.554	Xiphophorus_couchianus
ENSG00000165732	DDX21	82	68.995	ENSXMAG00000008199	ddx21	83	67.353	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001649	osteoblast differentiation	16210410.	HDA	Process
GO:0002735	positive regulation of myeloid dendritic cell cytokine production	-	IEA	Process
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0003725	double-stranded RNA binding	-	IEA	Function
GO:0004004	ATP-dependent RNA helicase activity	9461305.	IDA	Function
GO:0004004	ATP-dependent RNA helicase activity	25470060.	IMP	Function
GO:0005515	protein binding	15034300.21044950.23652018.25416956.30021884.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005634	nucleus	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005730	nucleolus	-	IDA	Component
GO:0005739	mitochondrion	-	IEA	Component
GO:0005829	cytosol	-	ISS	Component
GO:0006364	rRNA processing	-	IEA	Process
GO:0006366	transcription by RNA polymerase II	25470060.	IMP	Process
GO:0016020	membrane	16210410.19946888.	HDA	Component
GO:0019843	rRNA binding	25470060.	IDA	Function
GO:0030515	snoRNA binding	25470060.	IDA	Function
GO:0035198	miRNA binding	28431233.	IDA	Function
GO:0042802	identical protein binding	-	IEA	Function
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	-	ISS	Process
GO:0043330	response to exogenous dsRNA	-	IEA	Process
GO:0045087	innate immune response	-	IEA	Process
GO:0045815	positive regulation of gene expression, epigenetic	-	TAS	Process
GO:0051607	defense response to virus	-	IEA	Process
GO:0097322	7SK snRNA binding	25470060.	IDA	Function

EuRBPDB

Note: to get the extension of tumor abbreviations.

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Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

PRI

Literatures

Expression

Transcripts

Gene Model

PPI

Paralogs

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.