Cancer | Chr | Position | Mutation Type | dbSNP | Protein-change | Allele Freq | RBD |
---|---|---|---|---|---|---|---|
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BRCA | |||||||
BRCA | |||||||
CESC | |||||||
CESC | |||||||
CESC | |||||||
CESC | |||||||
CESC | |||||||
CESC | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
ESCA | |||||||
GBM | |||||||
GBM | |||||||
HNSC | |||||||
HNSC | |||||||
KIRC | |||||||
KIRP | |||||||
LIHC | |||||||
LIHC | |||||||
LIHC | |||||||
LUAD | |||||||
LUSC | |||||||
LUSC | |||||||
OV | |||||||
OV | |||||||
READ | |||||||
SARC | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
THYM | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC |
Cancer | Type | Freq | Q-value |
---|---|---|---|
ESCA | |||
TGCT |
Cancer | P-value | Q-value |
---|---|---|
THYM | ||
STAD | ||
MESO | ||
ACC | ||
KIRP | ||
PAAD | ||
PCPG | ||
CESC | ||
LAML | ||
KICH | ||
LIHC | ||
DLBC | ||
LGG | ||
THCA | ||
LUAD | ||
UVM | ||
OV |
Transcript ID | Name | Length | RefSeq ID | Protein ID | Length | RefSeq ID | UniportKB ID |
---|---|---|---|---|---|---|---|
ENST00000535307 | FEN1-202 | 768 | - | ENSP00000460402 | 154 (aa) | - | I3L3E9 |
ENST00000535723 | FEN1-203 | 776 | - | ENSP00000445692 | 165 (aa) | - | F5H1Y3 |
ENST00000305885 | FEN1-201 | 2296 | - | ENSP00000305480 | 380 (aa) | - | P39748 |
ensgID | Trait | pValue | Pubmed ID |
---|---|---|---|
ENSG00000168496 | alpha-Linolenic Acid | 8.5920000E-060 | 21829377 |
ENSG00000168496 | Docosahexaenoic Acids | 5.2470000E-006 | 21829377 |
ENSG00000168496 | docosapentaenoic acid | 1.3800000E-139 | 21829377 |
ENSG00000168496 | Eicosapentaenoic Acid | 5.9610000E-055 | 21829377 |
ENSG00000168496 | Metabolism | 9E-14 | 24816252 |
ENSG00000168496 | Platelet Count | 3E-10 | 22139419 |
ENSG00000168496 | Eicosapentaenoic Acid | 6E-55 | 21829377 |
ENSG00000168496 | Eicosapentaenoic Acid | 5E-58 | 21829377 |
ENSG00000168496 | alpha-Linolenic Acid | 9E-60 | 21829377 |
ENSG00000168496 | docosapentaenoic acid | 1E-139 | 21829377 |
ENSG00000168496 | Trans Fatty Acids | 5E-13 | 25646338 |
ENSG00000168496 | Trans Fatty Acids | 1E-12 | 25646338 |
ENSG00000168496 | Insulin Resistance | 3E-9 | 23378610 |
ENSG00000168496 | Inflammatory Bowel Diseases | 2E-15 | 23128233 |
ENSG00000168496 | Fatty Acids | 1E-9 | 25500335 |
ENSG00000168496 | Linoleic Acid | 1E-9 | 25500335 |
ENSG00000168496 | Trans Fatty Acids | 4E-13 | 25646338 |
ENSG00000168496 | Crohn Disease | 9E-7 | 28067908 |
ENSG00000168496 | Fatty Acids | 3E-19 | 25500335 |
ensgID | SNP | Chromosome | Position | SNP-risk | Trait | PubmedID | 95% CI | Or or BEAT | EFO ID |
---|---|---|---|---|---|---|---|---|---|
ENSG00000168496 | rs4246215 | 11 | 61796827 | T | Platelet count | 22139419 | [1.69-3.22] 10^9/l increase | 2.451 | EFO_0004309 |
ENSG00000168496 | rs4246215 | 11 | 61796827 | ? | Crohn's disease | 28067908 | EFO_0000384 | ||
ENSG00000168496 | rs4246215 | 11 | 61796827 | T | Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid) | 21829377 | [NR] % increase | 0.02 | EFO_0007759 |
ENSG00000168496 | rs4246215 | 11 | 61796827 | T | Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid) | 21829377 | [NR] % decrease | 0.08 | EFO_0007760 |
ENSG00000168496 | rs4246215 | 11 | 61796827 | T | Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid) | 21829377 | [NR] % decrease | 0.07 | EFO_0006809 |
ENSG00000168496 | rs4246215 | 11 | 61796827 | T | Inflammatory bowel disease | 23128233 | [1.046-1.112] | 1.079 | EFO_0003767 |
ENSG00000168496 | rs4246215 | 11 | 61796827 | ? | Red blood cell fatty acid levels | 25500335 | [NR] unit increase | 0.113 | EFO_0005110|EFO_0006807 |
ENSG00000168496 | rs4246215 | 11 | 61796827 | T | Trans fatty acid levels | 25646338 | [0.0023-0.0039] unit increase | 0.0031 | EFO_0006824|EFO_0006821 |
Ensembl ID | Gene Symbol | Coverage | Identiy | Ortholog | Gene Symbol | Coverage | Identiy | Species |
---|---|---|---|---|---|---|---|---|
ENSG00000168496 | FEN1 | 100 | 69.697 | FBgn0025832 | Fen1 | 100 | 62.857 | Drosophila_melanogaster |
Go ID | Go_term | PubmedID | Evidence | Category |
---|---|---|---|---|
GO:0000287 | magnesium ion binding | 21873635. | IBA | Function |
GO:0000724 | double-strand break repair via homologous recombination | - | TAS | Process |
GO:0000784 | nuclear chromosome, telomeric region | 19135898. | HDA | Component |
GO:0000784 | nuclear chromosome, telomeric region | 24270157. | IDA | Component |
GO:0003677 | DNA binding | 11986308. | IMP | Function |
GO:0003684 | damaged DNA binding | 8007985. | TAS | Function |
GO:0003690 | double-stranded DNA binding | 8131753. | TAS | Function |
GO:0004519 | endonuclease activity | 8131753. | TAS | Function |
GO:0004523 | RNA-DNA hybrid ribonuclease activity | 21873635. | IBA | Function |
GO:0004523 | RNA-DNA hybrid ribonuclease activity | 7961795. | IDA | Function |
GO:0004527 | exonuclease activity | 9778254. | TAS | Function |
GO:0005515 | protein binding | 9305916.11430825.11598021.14657243.14688284.15576034.18499658.18692475.22551069.26496610.26751069.29997244. | IPI | Function |
GO:0005634 | nucleus | 21873635. | IBA | Component |
GO:0005634 | nucleus | 7961795.18995831. | IDA | Component |
GO:0005654 | nucleoplasm | - | TAS | Component |
GO:0005730 | nucleolus | - | IDA | Component |
GO:0005739 | mitochondrion | 18995831. | IDA | Component |
GO:0006260 | DNA replication | 9778254. | TAS | Process |
GO:0006281 | DNA repair | 8007985. | TAS | Process |
GO:0006284 | base-excision repair | - | IEA | Process |
GO:0006302 | double-strand break repair | 8131753. | TAS | Process |
GO:0007613 | memory | - | IEA | Process |
GO:0008309 | double-stranded DNA exodeoxyribonuclease activity | 8131753. | TAS | Function |
GO:0008409 | 5'-3' exonuclease activity | 21873635. | IBA | Function |
GO:0008409 | 5'-3' exonuclease activity | 7961795. | IDA | Function |
GO:0009650 | UV protection | 8007985. | TAS | Process |
GO:0016020 | membrane | 19946888. | HDA | Component |
GO:0017108 | 5'-flap endonuclease activity | 21873635. | IBA | Function |
GO:0017108 | 5'-flap endonuclease activity | 18995831. | IDA | Function |
GO:0017108 | 5'-flap endonuclease activity | 8621570.11986308. | IMP | Function |
GO:0017108 | 5'-flap endonuclease activity | - | TAS | Function |
GO:0030145 | manganese ion binding | 21873635. | IBA | Function |
GO:0032201 | telomere maintenance via semi-conservative replication | - | TAS | Process |
GO:0032991 | protein-containing complex | 25378300. | IDA | Component |
GO:0043137 | DNA replication, removal of RNA primer | 18995831. | IDA | Process |
GO:0045876 | positive regulation of sister chromatid cohesion | 18499658. | IMP | Process |
GO:0048256 | flap endonuclease activity | 21873635. | IBA | Function |
GO:0048256 | flap endonuclease activity | 18499658. | IDA | Function |
GO:0090305 | nucleic acid phosphodiester bond hydrolysis | 18499658. | IDA | Process |
GO:0090502 | RNA phosphodiester bond hydrolysis, endonucleolytic | - | IEA | Process |