EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
26683227	SHIP represses lung inflammation and inhibits mammary tumor metastasis in BALB/c mice.	Oncotarget	2016 Jan 26	Hamilton MJ	doi: 10.18632/oncotarget.6611.
25723258	The tumor suppressor SHIP1 colocalizes in nucleolar cavities with p53 and components of PML nuclear bodies.	Nucleus	2015	Ehm P	doi: 10.1080/19491034.2015.1022701

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr2	233182412	Missense_Mutation	rs772915023	S692G	0.47	Exo_endo_phos
BLCA	chr2	233122226	Frame_Shift_Del	novel	*D107Tfs11**	0.17
BLCA	chr2	233163858	Silent	NA	I464I	0.82
BLCA	chr2	233198131	Silent	NA	I910I	0.17
BLCA	chr2	233204225	Silent	rs752632052	L1025L	0.31
BLCA	chr2	233122146	Missense_Mutation	NA	D80N	0.15
BLCA	chr2	233193915	Missense_Mutation	NA	E850D	0.24
BLCA	chr2	233193945	Silent	novel	T860T	0.4
BLCA	chr2	233170534	Silent	NA	Q610Q	0.35
BLCA	chr2	233189933	Silent	NA	S814S	0.09
BRCA	chr2	233185911	Missense_Mutation	NA	E782K	0.23
BRCA	chr2	233122253	Missense_Mutation	NA	D115E	0.37
BRCA	chr2	233171097	Missense_Mutation	rs781285468	R645H	0.16	Exo_endo_phos
BRCA	chr2	233122113	Nonsense_Mutation	NA	E69*	0.61
BRCA	chr2	233060577	Silent	rs754639374	S33S	0.47
BRCA	chr2	233169355	Missense_Mutation	novel	G536R	0.1	Exo_endo_phos
BRCA	chr2	233146364	Splice_Region	novel		0.23
BRCA	chr2	233204320	Missense_Mutation	rs758989076	S1057L	0.2
BRCA	chr2	233170113	Silent	rs759745293	T580T	0.08
CESC	chr2	233163749	Missense_Mutation	NA	S428C	0.15	Exo_endo_phos
CESC	chr2	233204281	Missense_Mutation	rs201032928	R1044Q	0.14
CESC	chr2	233195463	Silent	rs768413369	H887H	0.28
CESC	chr2	233204383	Missense_Mutation	NA	V1078A	0.5
CESC	chr2	233164339	Silent	rs201454690	I490I	0.17
CESC	chr2	233170103	Missense_Mutation	novel	H577R	0.49	Exo_endo_phos
CESC	chr2	233171145	Missense_Mutation	NA	A661V	0.37	Exo_endo_phos
CESC	chr2	233204280	Missense_Mutation	rs769891270	R1044W	0.34
CESC	chr2	233207018	3'UTR	rs539966442		0.5
CESC	chr2	233207259	3'UTR	novel		0.26
CESC	chr2	233198134	Silent	novel	I911I	0.64
CESC	chr2	233204374	Missense_Mutation	rs759195359	G1075D	0.4
CESC	chr2	233169393	Missense_Mutation	NA	K548N	0.26	Exo_endo_phos
CESC	chr2	233079366	Silent	NA	L56L	0.23
CHOL	chr2	233161744	Missense_Mutation	novel	Q386H	0.5
COAD	chr2	233198181	Missense_Mutation	NA	L927P	0.32
COAD	chr2	233122238	Silent	rs780515179	D110D	0.29
COAD	chr2	233170028	Missense_Mutation	NA	R552Q	0.24	Exo_endo_phos
COAD	chr2	233193816	Missense_Mutation	NA	E817D	0.38
COAD	chr2	233193909	Frame_Shift_Del	NA	*E850Rfs19**	0.36
COAD	chr2	233198256	Missense_Mutation	rs375229594	P952L	0.2
COAD	chr2	233198234	Missense_Mutation	rs746591123	D945N	0.51
COAD	chr2	233171074	Silent	novel	E637E	0.08
COAD	chr2	233171126	Missense_Mutation	rs756001826	A655T	0.24	Exo_endo_phos
COAD	chr2	233206750	3'UTR	rs370954433		0.22
COAD	chr2	233177295	Nonsense_Mutation	NA	R674*	0.08	Exo_endo_phos
COAD	chr2	233079348	Missense_Mutation	rs748315737	V50I	0.34
COAD	chr2	233170106	Missense_Mutation	rs546876794	R578H	0.2	Exo_endo_phos
COAD	chr2	233163823	Missense_Mutation	NA	E453K	0.25	Exo_endo_phos
COAD	chr2	233060599	Missense_Mutation	NA	A41T	0.28
COAD	chr2	233170028	Missense_Mutation	NA	R552Q	0.19	Exo_endo_phos
COAD	chr2	233204310	Missense_Mutation	rs192196528	G1054S	0.24
COAD	chr2	233189860	Missense_Mutation	NA	I790T	0.31
DLBC	chr2	233185877	Silent	novel	E770E	0.34
DLBC	chr2	233169311	Missense_Mutation	novel	K521R	0.07	Exo_endo_phos
ESCA	chr2	233125756	Missense_Mutation	rs755468463	V121M	0.45
ESCA	chr2	233206863	3'UTR	novel		0.62
GBM	chr2	233204158	Missense_Mutation	rs142742228	T1003M	0.33
GBM	chr2	233079340	Missense_Mutation	novel	R47Q	0.22
GBM	chr2	233161730	Nonsense_Mutation	novel	E382*	0.23
GBM	chr2	233163735	Silent	rs377021577	T423T	0.43
GBM	chr2	233130513	Missense_Mutation	rs778985157	P177L	0.1
GBM	chr2	233079348	Missense_Mutation	rs748315737	V50I	0.51
GBM	chr2	233195417	Missense_Mutation	NA	R872H	0.21
GBM	chr2	233170028	Missense_Mutation	NA	R552Q	0.26	Exo_endo_phos
GBM	chr2	233204635	Missense_Mutation	novel	R1162H	0.23
HNSC	chr2	233204144	Missense_Mutation	novel	K998N	0.25
HNSC	chr2	233182481	Missense_Mutation	novel	Q715K	0.22
HNSC	chr2	233204294	Silent	rs762287573	P1048P	0.42
HNSC	chr2	233079349	Missense_Mutation	novel	V50A	0.15
HNSC	chr2	233130560	Missense_Mutation	novel	A193T	0.22
HNSC	chr2	233060591	Missense_Mutation	NA	R38Q	0.23
HNSC	chr2	233195408	Missense_Mutation	rs755894738	K869R	0.22
HNSC	chr2	233195463	Silent	rs768413369	H887H	0.19
HNSC	chr2	233185866	Missense_Mutation	novel	E767Q	0.27
KIRP	chr2	233130642	Missense_Mutation	novel	L220H	0.49
KIRP	chr2	233204303	Silent	rs773563073	P1051P	0.28
LAML	chr2	233161812	Missense_Mutation	novel	G409D	0.13	Exo_endo_phos
LGG	chr2	233204372	Silent	rs771288486	P1074P	0.08
LGG	chr2	233204279	Silent	rs372583486	P1043P	0.49
LGG	chr2	233122239	Missense_Mutation	rs373149593	D111N	0.43
LIHC	chr2	233204138	Silent	NA	L996L	0.35
LIHC	chr2	233170115	Missense_Mutation	novel	H581L	0.23	Exo_endo_phos
LUAD	chr2	233204308	Missense_Mutation	NA	P1053L	0.11
LUAD	chr2	233198222	Missense_Mutation	novel	A941S	0.17
LUAD	chr2	233182456	Silent	NA	A706A	0.22
LUAD	chr2	233195461	Missense_Mutation	NA	H887Y	0.26
LUAD	chr2	233060565	Silent	NA	L29L	0.22
LUAD	chr2	233060608	Missense_Mutation	novel	V44M	0.11
LUAD	chr2	233060570	Missense_Mutation	novel	R31L	0.25
LUAD	chr2	233163729	Silent	NA	K421K	0.03
LUAD	chr2	233198179	Silent	novel	P926P	0.23
LUAD	chr2	233193869	Missense_Mutation	novel	T835R	0.12
LUAD	chr2	233163903	Splice_Region	NA	T479T	0.46
LUAD	chr2	233193833	Missense_Mutation	novel	R823Q	0.35
LUAD	chr2	233198197	Silent	NA	T932T	0.12
LUAD	chr2	233193894	Missense_Mutation	NA	L843F	0.17
LUAD	chr2	233198310	Missense_Mutation	novel	I970K	0.31
LUSC	chr2	233079333	Splice_Site	novel	X45_splice	0.1
LUSC	chr2	233198139	Missense_Mutation	novel	P913H	0.64
LUSC	chr2	233170087	Missense_Mutation	novel	P572S	0.21	Exo_endo_phos
LUSC	chr2	233122117	Missense_Mutation	NA	G70V	0.46
LUSC	chr2	233170572	Missense_Mutation	novel	E623G	0.24	Exo_endo_phos
LUSC	chr2	233198316	Missense_Mutation	novel	P972L	0.37
LUSC	chr2	233060601	Silent	novel	A41A	0.36
LUSC	chr2	233163783	Silent	rs531976699	A439A	0.06
LUSC	chr2	233170584	Missense_Mutation	novel	Q627L	0.48	Exo_endo_phos
LUSC	chr2	233170585	Silent	novel	Q627Q	0.5
LUSC	chr2	233195413	Nonsense_Mutation	NA	E871*	0.62
LUSC	chr2	233130539	Missense_Mutation	novel	D186Y	0.19
LUSC	chr2	233182408	Splice_Site	NA	X691_splice	0.17
LUSC	chr2	233125821	Missense_Mutation	novel	E142D	0.3
LUSC	chr2	233198362	Missense_Mutation	novel	R987S	0.43
LUSC	chr2	233161721	Splice_Region	novel		0.5
LUSC	chr2	233204427	Missense_Mutation	NA	E1093K	0.46
LUSC	chr2	233204293	Missense_Mutation	NA	P1048Q	0.57
LUSC	chr2	233060567	Missense_Mutation	novel	V30A	0.34
LUSC	chr2	233193889	Nonsense_Mutation	NA	E842*	0.1
LUSC	chr2	233204570	Silent	novel	R1140R	0.4
LUSC	chr2	233125819	Nonsense_Mutation	novel	E142*	0.21
LUSC	chr2	233182463	Missense_Mutation	NA	E709Q	0.38
OV	chr2	233177301	Missense_Mutation	NA	L676I	0.89	Exo_endo_phos
OV	chr2	233170165	Splice_Site	novel	X597_splice	0.44
OV	chr2	233171069	Missense_Mutation	NA	E636K	0.37	Exo_endo_phos
OV	chr2	233198124	Missense_Mutation	novel	T908I	0.25
OV	chr2	233204277	Missense_Mutation	NA	P1043T	0.32
OV	chr2	233163788	Missense_Mutation	NA	Y441C	0.23	Exo_endo_phos
OV	chr2	233198327	Silent	novel	L976L	0.22
OV	chr2	233198322	Missense_Mutation	novel	K974M	0.1
OV	chr2	233122239	Missense_Mutation	novel	D111H	0.13
PAAD	chr2	233177348	Splice_Site	novel	X691_splice	0.24
PCPG	chr2	233193825	Silent	novel	I820I	0.31
PRAD	chr2	233125768	Missense_Mutation	rs777393014	E125K	0.17
PRAD	chr2	233060600	Missense_Mutation	NA	A41V	0.16
PRAD	chr2	233125758	Silent	rs779197283	V121V	0.23
PRAD	chr2	233198148	Missense_Mutation	novel	M916T	0.38
READ	chr2	233170536	Missense_Mutation	novel	Y611C	0.09	Exo_endo_phos
READ	chr2	233170028	Missense_Mutation	NA	R552Q	0.14	Exo_endo_phos
READ	chr2	233195400	Missense_Mutation	NA	D866E	0.26
READ	chr2	233163767	Missense_Mutation	NA	T434M	0.43	Exo_endo_phos
READ	chr2	233170028	Missense_Mutation	NA	R552Q	0.35	Exo_endo_phos
SARC	chr2	233146406	Missense_Mutation	novel	R292W	0.1
SARC	chr2	233207260	3'UTR	novel		0.71
SARC	chr2	233163772	Missense_Mutation	novel	D436N	0.17	Exo_endo_phos
SARC	chr2	233146369	Splice_Region	novel	V279V	0.8
SARC	chr2	233198150	Missense_Mutation	NA	G917R	0.21
SKCM	chr2	233125819	Missense_Mutation	NA	E142K	0.47
SKCM	chr2	233079339	Missense_Mutation	NA	R47W	0.32
SKCM	chr2	233198102	Missense_Mutation	NA	P901S	0.24
SKCM	chr2	233204419	Missense_Mutation	novel	S1090F	0.45
SKCM	chr2	233169339	Silent	novel	F530F	0.57
SKCM	chr2	233198320	Silent	novel	K973K	0.35
SKCM	chr2	233171105	Silent	NA	R648R	0.44
SKCM	chr2	233177296	Missense_Mutation	NA	R674Q	0.33	Exo_endo_phos
SKCM	chr2	233170053	Silent	rs779602924	L560L	0.3
SKCM	chr2	233060563	Missense_Mutation	NA	L29F	0.31
SKCM	chr2	233122239	Missense_Mutation	rs373149593	D111N	0.33
SKCM	chr2	233163794	Missense_Mutation	NA	P443L	0.18	Exo_endo_phos
SKCM	chr2	233185887	Missense_Mutation	NA	G774R	0.17
SKCM	chr2	233198254	Silent	NA	S951S	0.28
SKCM	chr2	233204262	Missense_Mutation	NA	E1038K	0.23
SKCM	chr2	233125844	Missense_Mutation	NA	P150L	0.24
SKCM	chr2	233122217	Silent	novel	L103L	0.31
SKCM	chr2	233125914	Silent	novel	T173T	0.26
SKCM	chr2	233060524	Missense_Mutation	NA	E16K	0.26
SKCM	chr2	233204230	Missense_Mutation	NA	S1027F	0.38
SKCM	chr2	233177321	Silent	novel	L682L	0.19
SKCM	chr2	233125847	Missense_Mutation	NA	R151P	0.5
SKCM	chr2	233193949	Missense_Mutation	NA	E862K	0.3
SKCM	chr2	233198255	Missense_Mutation	NA	P952S	0.61
SKCM	chr2	233130602	Missense_Mutation	rs774932127	P207S	0.7
SKCM	chr2	233198361	Missense_Mutation	novel	R987K	0.23
SKCM	chr2	233130638	Missense_Mutation	NA	E219K	0.44
SKCM	chr2	233125789	Missense_Mutation	NA	P132S	0.52
SKCM	chr2	233163853	Missense_Mutation	NA	E463K	0.57	Exo_endo_phos
SKCM	chr2	233163759	Silent	NA	Q431Q	0.25
SKCM	chr2	233204393	Silent	NA	P1081P	0.12
SKCM	chr2	233163725	Missense_Mutation	NA	K420T	0.48	Exo_endo_phos
SKCM	chr2	233195439	Silent	NA	K879K	0.3
SKCM	chr2	233122173	Missense_Mutation	NA	E89K	0.47
SKCM	chr2	233169304	Splice_Site	NA	X519_splice	0.33
SKCM	chr2	233204230	Missense_Mutation	NA	S1027F	0.23
SKCM	chr2	233204371	Missense_Mutation	NA	P1074L	0.24
SKCM	chr2	233204372	Silent	rs771288486	P1074P	0.25
SKCM	chr2	233171072	Missense_Mutation	NA	E637K	0.35	Exo_endo_phos
SKCM	chr2	233184478	Silent	NA	S744S	0.2
SKCM	chr2	233189889	Nonsense_Mutation	NA	Q800*	0.32
SKCM	chr2	233204330	Silent	rs758404644	I1060I	0.23
SKCM	chr2	233198159	Missense_Mutation	novel	P920S	0.19
SKCM	chr2	233198160	Missense_Mutation	novel	P920L	0.19
SKCM	chr2	233170057	Missense_Mutation	NA	F562L	0.28	Exo_endo_phos
SKCM	chr2	233130638	Missense_Mutation	NA	E219K	0.54
SKCM	chr2	233204530	Missense_Mutation	NA	S1127L	0.67
SKCM	chr2	233170571	Missense_Mutation	NA	E623K	0.12	Exo_endo_phos
SKCM	chr2	233198131	Silent	NA	I910I	0.31
SKCM	chr2	233204230	Missense_Mutation	NA	S1027F	0.26
SKCM	chr2	233163792	Silent	NA	I442I	0.24
SKCM	chr2	233169339	Silent	novel	F530F	0.16
SKCM	chr2	233170130	Missense_Mutation	NA	G586E	0.11	Exo_endo_phos
SKCM	chr2	233163745	Missense_Mutation	NA	L427F	0.08	Exo_endo_phos
SKCM	chr2	233204230	Missense_Mutation	NA	S1027F	0.48
SKCM	chr2	233198150	Missense_Mutation	NA	G917R	0.45
SKCM	chr2	233198351	Missense_Mutation	NA	L984F	0.46
SKCM	chr2	233163745	Missense_Mutation	NA	L427F	0.25	Exo_endo_phos
SKCM	chr2	233204358	Missense_Mutation	NA	R1070C	0.15
SKCM	chr2	233204247	Missense_Mutation	NA	P1033S	0.61
SKCM	chr2	233193906	Silent	novel	F847F	0.29
SKCM	chr2	233170579	Missense_Mutation	novel	R625S	0.23	Exo_endo_phos
SKCM	chr2	233169305	Missense_Mutation	novel	G519E	0.13	Exo_endo_phos
SKCM	chr2	233169306	Splice_Region	novel	G519G	0.13
SKCM	chr2	233198131	Silent	NA	I910I	0.54
SKCM	chr2	233122239	Missense_Mutation	rs373149593	D111N	0.45
SKCM	chr2	233169383	Missense_Mutation	NA	G545E	0.25	Exo_endo_phos
SKCM	chr2	233198218	Silent	rs755512057	P939P	0.46
SKCM	chr2	233125819	Missense_Mutation	NA	E142K	0.08
SKCM	chr2	233185872	Missense_Mutation	novel	E769K	0.42
STAD	chr2	233163828	Frame_Shift_Del	novel	L456*	0.14	Exo_endo_phos
STAD	chr2	233130531	Missense_Mutation	novel	A183V	0.24
STAD	chr2	233204157	Missense_Mutation	NA	T1003A	0.25
STAD	chr2	233122142	Missense_Mutation	NA	K78N	0.13
STAD	chr2	233163849	Nonsense_Mutation	NA	W461*	0.07	Exo_endo_phos
STAD	chr2	233184428	Frame_Shift_Ins	novel	*G729Rfs4**	0.28
STAD	chr2	233193852	Silent	rs377226097	T829T	0.2
TGCT	chr2	233060566	Missense_Mutation	novel	V30L	0.23
THCA	chr2	233125903	Missense_Mutation	NA	S170C	0.18
UCEC	chr2	233185855	Missense_Mutation	novel	S763N	0.09
UCEC	chr2	233164400	Missense_Mutation	novel	K511E	0.07	Exo_endo_phos
UCEC	chr2	233198212	Missense_Mutation	novel	Q937H	0.36
UCEC	chr2	233204158	Missense_Mutation	rs142742228	T1003M	0.34
UCEC	chr2	233207117	3'UTR	novel		0.44
UCEC	chr2	233130613	Missense_Mutation	novel	K210N	0.08
UCEC	chr2	233164383	Missense_Mutation	novel	I505S	0.08	Exo_endo_phos
UCEC	chr2	233182489	Silent	novel	V717V	0.41
UCEC	chr2	233204211	Missense_Mutation	novel	L1021M	0.52
UCEC	chr2	233206735	3'UTR	novel		0.41
UCEC	chr2	233189856	Missense_Mutation	NA	P789S	0.47
UCEC	chr2	233204278	Missense_Mutation	novel	P1043L	0.53
UCEC	chr2	233207110	3'UTR	novel		0.32
UCEC	chr2	233122118	Silent	rs750368402	G70G	0.47
UCEC	chr2	233147521	Silent	rs761996196	D319D	0.17
UCEC	chr2	233170027	Nonsense_Mutation	NA	R552*	0.06	Exo_endo_phos
UCEC	chr2	233060522	Missense_Mutation	NA	A15V	0.27
UCEC	chr2	233193957	Silent	NA	L864L	0.28
UCEC	chr2	233204375	Silent	novel	G1075G	0.27
UCEC	chr2	233204279	Silent	rs372583486	P1043P	0.25
UCEC	chr2	233193813	Splice_Region	rs114395116	G816G	0.4
UCEC	chr2	233198339	Missense_Mutation	novel	A980T	0.5
UCEC	chr2	233198362	Silent	NA	R987R	0.33
UCEC	chr2	233206735	3'UTR	novel		0.33
UCEC	chr2	233207418	3'UTR	novel		0.67
UCEC	chr2	233189915	Silent	novel	S808S	0.39
UCEC	chr2	233170538	Missense_Mutation	rs754601445	A612T	0.44	Exo_endo_phos
UCEC	chr2	233170028	Missense_Mutation	NA	R552Q	0.4	Exo_endo_phos
UCEC	chr2	233207371	3'UTR	novel		0.36
UCEC	chr2	233079378	Missense_Mutation	novel	D60Y	0.46
UCEC	chr2	233207229	3'UTR	novel		0.33
UCEC	chr2	233164386	Missense_Mutation	NA	C506Y	0.5	Exo_endo_phos
UCEC	chr2	233189894	Frame_Shift_Del	novel	*H801Qfs24**	0.41
UCEC	chr2	233171140	Missense_Mutation	NA	Q659H	0.36	Exo_endo_phos
UCEC	chr2	233163713	Frame_Shift_Del	NA	*P418Lfs31**	0.4	Exo_endo_phos
UCEC	chr2	233122174	Missense_Mutation	novel	E89G	0.23
UCEC	chr2	233207191	3'UTR	novel		0.1
UCEC	chr2	233170547	Missense_Mutation	NA	L615M	0.35	Exo_endo_phos
UCEC	chr2	233189928	Missense_Mutation	novel	E813K	0.1
UCEC	chr2	233060363	5'Flank	novel		0.47
UCEC	chr2	233146187	Missense_Mutation	rs367582064	N260S	0.37
UCEC	chr2	233198186	Missense_Mutation	rs760843259	V929M	0.06
UCEC	chr2	233163711	Silent	rs569340799	N415N	0.23
UCEC	chr2	233122235	Silent	rs746407643	G109G	0.31
UCEC	chr2	233170113	Silent	rs759745293	T580T	0.49
UCEC	chr2	233204186	Silent	rs762199661	T1012T	0.4
UCEC	chr2	233207132	3'UTR	NA		0.34
UCEC	chr2	233182426	Silent	NA	I696I	0.28
UCEC	chr2	233169321	Frame_Shift_Del	novel	*V526Cfs10**	0.42	Exo_endo_phos
UCEC	chr2	233125894	Nonsense_Mutation	novel	R167*	0.36
UCEC	chr2	233169348	Silent	novel	T533T	0.25
UCEC	chr2	233170106	Missense_Mutation	rs546876794	R578H	0.24	Exo_endo_phos
UCEC	chr2	233204414	Silent	novel	C1088C	0.23
UCEC	chr2	233177296	Missense_Mutation	NA	R674Q	0.33	Exo_endo_phos
UCEC	chr2	233193851	Missense_Mutation	rs372568250	T829M	0.25
UCEC	chr2	233164320	Missense_Mutation	rs376107758	T484M	0.38	Exo_endo_phos
UCEC	chr2	233204278	Missense_Mutation	novel	P1043Q	0.26
UCEC	chr2	233170113	Silent	rs759745293	T580T	0.36
UCEC	chr2	233169375	Missense_Mutation	novel	L542F	0.28	Exo_endo_phos
UCEC	chr2	233122173	Missense_Mutation	NA	E89K	0.44
UCEC	chr2	233125890	Missense_Mutation	novel	F165L	0.27
UCEC	chr2	233170542	Missense_Mutation	NA	D613G	0.27	Exo_endo_phos
UCEC	chr2	233206792	3'UTR	novel		0.2
UCEC	chr2	233122136	Silent	novel	F76F	0.48
UCEC	chr2	233164321	Silent	NA	T484T	0.27
UCEC	chr2	233195426	Missense_Mutation	novel	S875F	0.34
UCEC	chr2	233198257	Silent	rs530915376	P952P	0.45
UCEC	chr2	233170162	Missense_Mutation	novel	W597R	0.12	Exo_endo_phos
UCS	chr2	233161782	Missense_Mutation	rs777189163	P399L	0.58

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BLCA	DEL	0.4338	2.0711e-36
CESC	DEL	0.3695	3.4658e-41
HNSC	DEL	0.2146	1.278e-25
KIRP	DEL	0.0417	5.174e-05
LUSC	DEL	0.2675	1.3904e-19
MESO	DEL	0.092	0.014499
PAAD	AMP	0.0652	0.1091
PAAD	DEL	0.0489	0.2014
SARC	DEL	0.358	7.1647e-24
TGCT	DEL	0.0667	0.062762
THCA	DEL	0.024	0.040844
THYM	DEL	0.0325	0.10691
UCEC	DEL	0.0686	0.00045104
UVM	DEL	0.0375	0.024639

Survival Analysis

Cancer	P-value	Q-value
SARC	0.0058	Kaplan-Meier Survival Analysis
ACC	0.026	Kaplan-Meier Survival Analysis
HNSC	0.0001	Kaplan-Meier Survival Analysis
SKCM	0.0001	Kaplan-Meier Survival Analysis
LUSC	0.048	Kaplan-Meier Survival Analysis
COAD	0.023	Kaplan-Meier Survival Analysis
BLCA	0.045	Kaplan-Meier Survival Analysis
CESC	0.0021	Kaplan-Meier Survival Analysis
UCEC	0.011	Kaplan-Meier Survival Analysis
LGG	0.0001	Kaplan-Meier Survival Analysis
LUAD	0.021	Kaplan-Meier Survival Analysis
UVM	0.024	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000168918 (Gene tree)
Gene ID: 3635
Gene Symbol: INPP5D
Alias: SHIP|hp51CN|SHIP1
Full Name: inositol polyphosphate-5-phosphatase D
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 147,937 bases
Position: chr2:233,059,967-233,207,903
Accession: 6079
RBP type: canonical RBP
Summary: This gene is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. The protein is also partly localized to the nucleus, where it may be involved in nuclear inositol phosphate signaling processes. Overall, the protein functions as a negative regulator of myeloid cell proliferation and survival. Mutations in this gene are associated with defects and cancers of the immune system. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2014]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000397421	Exo_endo_phos	PF03372.23	4.4e-09	1	1
ENSP00000352575	Exo_endo_phos	PF03372.23	9.2e-09	1	1
ENSP00000405338	Exo_endo_phos	PF03372.23	9.2e-09	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000467393	INPP5D-207	431	-	-	- (aa)	-	-
ENST00000493632	INPP5D-213	958	-	-	- (aa)	-	-
ENST00000451407	INPP5D-205	2545	-	-	- (aa)	-	-
ENST00000465281	INPP5D-206	568	-	-	- (aa)	-	-
ENST00000493078	INPP5D-212	401	-	-	- (aa)	-	-
ENST00000445964	INPP5D-204	4845	-	ENSP00000405338	1189 (aa)	-	Q92835
ENST00000417661	INPP5D-203	588	-	ENSP00000414835	130 (aa)	-	H7C403
ENST00000415617	INPP5D-202	3628	XM_017004004	ENSP00000397421	810 (aa)	XP_016859493	H0Y5Q9
ENST00000491070	INPP5D-211	528	-	ENSP00000473280	43 (aa)	-	R4GMN8
ENST00000474278	INPP5D-209	568	-	-	- (aa)	-	-
ENST00000496402	INPP5D-214	569	-	-	- (aa)	-	-
ENST00000359570	INPP5D-201	5274	-	ENSP00000352575	1188 (aa)	-	Q92835
ENST00000472517	INPP5D-208	527	-	-	- (aa)	-	-
ENST00000480983	INPP5D-210	439	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000168918's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa00562	Inositol phosphate metabolism	KEGG
hsa01100	Metabolic pathways	KEGG
hsa04070	Phosphatidylinositol signaling system	KEGG
hsa04662	B cell receptor signaling pathway	KEGG
hsa04664	Fc epsilon RI signaling pathway	KEGG
hsa04666	Fc gamma R-mediated phagocytosis	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000168918	Coronary Disease	7E-6	21378990
ENSG00000168918	Bronchodilator Agents	1E-6	26503814
ENSG00000168918	Forced Expiratory Volume	1E-6	26503814
ENSG00000168918	Pulmonary Disease, Chronic Obstructive	1E-6	26503814
ENSG00000168918	Alzheimer Disease	3E-8	24162737

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000168918	rs7425956	2	233080855	?	Colorectal adenoma (advanced)	29228715	[NR]	1.4108351	EFO_0005406
ENSG00000168918	rs7425956	2	233080855	?	Colorectal adenoma (advanced)	29228715	[NR]	1.3475273	EFO_0005406
ENSG00000168918	rs76999017	2	233067548	G	Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1)	26503814	[4.99-11.54] unit decrease	8.263	EFO_0005921\|GO_0097366\|EFO_0000341
ENSG00000168918	rs35349669	2	233159830	T	Alzheimer's disease (late onset)	24162737	[1.05-1.11]	1.08	EFO_0000249
ENSG00000168918	rs7584458	2	233185159	G	Perceived unattractiveness to mosquitoes	28199695	[0.066-0.162] unit increase	0.114029	EFO_0008380
ENSG00000168918	rs6708049	2	233078583	T	Self-reported math ability	30038396	[0.011-0.023] unit decrease	0.0167	EFO_0004875
ENSG00000168918	rs35349669	2	233159830	?	Alzheimer's disease or family history of Alzheimer's disease	29777097	[1.03595530394875-1.06937674771915]	1.0525334	EFO_0000249\|EFO_0009268
ENSG00000168918	rs10933431	2	233117202	?	Alzheimer's disease or family history of Alzheimer's disease	29777097			EFO_0000249\|EFO_0009268
ENSG00000168918	rs56235204	2	233205887	C	Neutrophil percentage of granulocytes	27863252	[0.032-0.05] unit increase	0.04122401	EFO_0007994
ENSG00000168918	rs10933436	2	233133771	A	Coronary heart disease	21378990	[1.04-1.09]	1.06	EFO_0001645
ENSG00000168918	rs56235204	2	233205887	C	Eosinophil percentage of granulocytes	27863252	[0.033-0.051] unit decrease	0.04167263	EFO_0007996
ENSG00000168918	rs1057258	2	233206983	T	Sum eosinophil basophil counts	27863252	[0.025-0.043] unit decrease	0.03417721	EFO_0005090\|EFO_0004842
ENSG00000168918	rs56235204	2	233205887	C	Eosinophil percentage of white cells	27863252	[0.033-0.051] unit decrease	0.04176084	EFO_0007991
ENSG00000168918	rs56235204	2	233205887	C	Eosinophil counts	27863252	[0.026-0.044] unit decrease	0.03490725	EFO_0004842
ENSG00000168918	rs9247	2	233204655	?	Eczema	30595370			HP_0000964
ENSG00000168918	rs35349669	2	233159830	T	Family history of Alzheimer's disease	30617256	NR unit increase	0.007522	EFO_0009268
ENSG00000168918	rs10933431	2	233117202	G	Family history of Alzheimer's disease	30617256	NR z-score decrease	4.708	EFO_0009268
ENSG00000168918	rs10933431	2	233117202	G	Alzheimer's disease (late onset)	30617256	NR z-score decrease	4.7898254	EFO_0000249
ENSG00000168918	rs35349669	2	233159830	T	Alzheimer's disease (late onset)	30617256	NR z-score increase	4.46	EFO_0000249
ENSG00000168918	rs35349669	2	233159830	T	Alzheimer's disease or family history of Alzheimer's disease	30617256	NR z-unit increase	5.85	EFO_0000249\|EFO_0009268
ENSG00000168918	rs10933431	2	233117202	G	Alzheimer's disease or family history of Alzheimer's disease	30617256	NR z-unit decrease	6.13	EFO_0000249\|EFO_0009268
ENSG00000168918	rs1057258	2	233206983	?	Eosinophil counts	30595370			EFO_0004842

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000168918's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000168918	INPP5D	99	56.559	ENSAPOG00000017974	inpp5d	99	56.166	Acanthochromis_polyacanthus
ENSG00000168918	INPP5D	95	90.396	ENSAMEG00000016368	INPP5D	99	90.396	Ailuropoda_melanoleuca
ENSG00000168918	INPP5D	99	56.790	ENSAOCG00000003888	inpp5d	99	56.313	Amphiprion_ocellaris
ENSG00000168918	INPP5D	99	54.996	ENSAPEG00000020416	inpp5d	98	54.530	Amphiprion_percula
ENSG00000168918	INPP5D	98	56.899	ENSATEG00000011360	inpp5d	97	56.633	Anabas_testudineus
ENSG00000168918	INPP5D	99	64.294	ENSACAG00000006121	INPP5D	99	63.800	Anolis_carolinensis
ENSG00000168918	INPP5D	98	57.018	ENSACLG00000024736	inpp5d	98	56.777	Astatotilapia_calliptera
ENSG00000168918	INPP5D	98	54.714	ENSAMXG00000004736	inpp5d	79	63.725	Astyanax_mexicanus
ENSG00000168918	INPP5D	100	88.362	ENSBTAG00000020173	INPP5D	100	88.362	Bos_taurus
ENSG00000168918	INPP5D	100	95.707	ENSCJAG00000013979	INPP5D	100	95.707	Callithrix_jacchus
ENSG00000168918	INPP5D	100	87.638	ENSCAFG00000011650	INPP5D	88	88.409	Canis_familiaris
ENSG00000168918	INPP5D	100	87.638	ENSCAFG00020023772	INPP5D	99	88.519	Canis_lupus_dingo
ENSG00000168918	INPP5D	100	88.324	ENSCHIG00000018691	INPP5D	100	88.324	Capra_hircus
ENSG00000168918	INPP5D	100	92.340	ENSTSYG00000012323	INPP5D	100	92.340	Carlito_syrichta
ENSG00000168918	INPP5D	100	84.937	ENSCAPG00000013229	INPP5D	97	84.937	Cavia_aperea
ENSG00000168918	INPP5D	94	90.728	ENSCPOG00000011364	INPP5D	97	90.728	Cavia_porcellus
ENSG00000168918	INPP5D	100	92.515	ENSCCAG00000019399	INPP5D	99	92.515	Cebus_capucinus
ENSG00000168918	INPP5D	100	97.654	ENSCATG00000014660	INPP5D	100	93.687	Cercocebus_atys
ENSG00000168918	INPP5D	100	85.201	ENSCLAG00000015629	INPP5D	99	85.117	Chinchilla_lanigera
ENSG00000168918	INPP5D	100	97.391	ENSCSAG00000006368	INPP5D	100	97.391	Chlorocebus_sabaeus
ENSG00000168918	INPP5D	99	68.464	ENSCPBG00000024343	INPP5D	99	68.464	Chrysemys_picta_bellii
ENSG00000168918	INPP5D	100	95.118	ENSCANG00000040141	INPP5D	96	95.118	Colobus_angolensis_palliatus
ENSG00000168918	INPP5D	100	88.107	ENSCGRG00001023640	Inpp5d	99	92.585	Cricetulus_griseus_chok1gshd
ENSG00000168918	INPP5D	100	87.010	ENSCGRG00000003828	Inpp5d	99	92.544	Cricetulus_griseus_crigri
ENSG00000168918	INPP5D	98	54.500	ENSCSEG00000002919	inpp5d	97	53.912	Cynoglossus_semilaevis
ENSG00000168918	INPP5D	98	55.736	ENSCVAG00000015388	inpp5d	97	55.365	Cyprinodon_variegatus
ENSG00000168918	INPP5D	99	54.900	ENSDARG00000074283	inpp5d	98	66.626	Danio_rerio
ENSG00000168918	INPP5D	100	86.765	ENSDNOG00000006291	-	99	87.564	Dasypus_novemcinctus
ENSG00000168918	INPP5D	100	86.394	ENSDORG00000015370	Inpp5d	99	86.432	Dipodomys_ordii
ENSG00000168918	INPP5D	100	89.474	ENSEASG00005019862	INPP5D	99	89.474	Equus_asinus_asinus
ENSG00000168918	INPP5D	100	89.557	ENSECAG00000019497	INPP5D	100	89.557	Equus_caballus
ENSG00000168918	INPP5D	97	55.306	ENSELUG00000008208	inpp5d	97	54.206	Esox_lucius
ENSG00000168918	INPP5D	100	85.151	ENSFCAG00000011321	INPP5D	91	85.151	Felis_catus
ENSG00000168918	INPP5D	99	67.837	ENSFALG00000013517	INPP5D	99	67.971	Ficedula_albicollis
ENSG00000168918	INPP5D	92	88.341	ENSFDAG00000019347	INPP5D	97	91.749	Fukomys_damarensis
ENSG00000168918	INPP5D	99	55.621	ENSFHEG00000009590	inpp5d	98	55.584	Fundulus_heteroclitus
ENSG00000168918	INPP5D	62	70.659	ENSGMOG00000019190	inpp5d	100	60.335	Gadus_morhua
ENSG00000168918	INPP5D	99	64.760	ENSGALG00000035498	INPP5D	99	64.508	Gallus_gallus
ENSG00000168918	INPP5D	98	55.905	ENSGAFG00000017284	inpp5d	97	55.377	Gambusia_affinis
ENSG00000168918	INPP5D	74	65.873	ENSGACG00000003813	inpp5d	99	66.100	Gasterosteus_aculeatus
ENSG00000168918	INPP5D	99	68.382	ENSGAGG00000001443	INPP5D	99	68.382	Gopherus_agassizii
ENSG00000168918	INPP5D	100	99.506	ENSGGOG00000000530	INPP5D	100	99.527	Gorilla_gorilla
ENSG00000168918	INPP5D	98	56.559	ENSHBUG00000013397	inpp5d	98	56.351	Haplochromis_burtoni
ENSG00000168918	INPP5D	100	86.884	ENSHGLG00000003850	INPP5D	99	86.884	Heterocephalus_glaber_female
ENSG00000168918	INPP5D	100	86.873	ENSHGLG00100002826	INPP5D	99	86.873	Heterocephalus_glaber_male
ENSG00000168918	INPP5D	100	54.902	ENSHCOG00000014071	inpp5d	91	53.049	Hippocampus_comes
ENSG00000168918	INPP5D	99	55.909	ENSIPUG00000010594	inpp5d	98	55.734	Ictalurus_punctatus
ENSG00000168918	INPP5D	100	88.610	ENSSTOG00000011273	INPP5D	97	88.610	Ictidomys_tridecemlineatus
ENSG00000168918	INPP5D	100	87.374	ENSJJAG00000022473	Inpp5d	94	91.713	Jaculus_jaculus
ENSG00000168918	INPP5D	98	55.385	ENSKMAG00000014854	inpp5d	97	55.432	Kryptolebias_marmoratus
ENSG00000168918	INPP5D	99	56.176	ENSLBEG00000025835	inpp5d	98	56.139	Labrus_bergylta
ENSG00000168918	INPP5D	99	59.746	ENSLOCG00000005346	inpp5d	97	59.475	Lepisosteus_oculatus
ENSG00000168918	INPP5D	100	87.248	ENSLAFG00000016159	INPP5D	99	86.997	Loxodonta_africana
ENSG00000168918	INPP5D	100	97.531	ENSMFAG00000032897	INPP5D	99	97.228	Macaca_fascicularis
ENSG00000168918	INPP5D	100	95.539	ENSMMUG00000009772	INPP5D	99	95.539	Macaca_mulatta
ENSG00000168918	INPP5D	100	96.215	ENSMNEG00000028451	INPP5D	99	96.215	Macaca_nemestrina
ENSG00000168918	INPP5D	100	96.549	ENSMLEG00000037654	INPP5D	100	96.549	Mandrillus_leucophaeus
ENSG00000168918	INPP5D	98	56.630	ENSMAMG00000009985	inpp5d	98	56.106	Mastacembelus_armatus
ENSG00000168918	INPP5D	98	56.340	ENSMZEG00005008710	inpp5d	98	56.133	Maylandia_zebra
ENSG00000168918	INPP5D	99	69.297	ENSMGAG00000001607	INPP5D	99	68.593	Meleagris_gallopavo
ENSG00000168918	INPP5D	100	74.231	ENSMAUG00000007862	Inpp5d	95	74.231	Mesocricetus_auratus
ENSG00000168918	INPP5D	100	90.909	ENSMICG00000006753	INPP5D	99	90.909	Microcebus_murinus
ENSG00000168918	INPP5D	100	87.255	ENSMOCG00000020774	Inpp5d	100	93.233	Microtus_ochrogaster
ENSG00000168918	INPP5D	99	54.798	ENSMMOG00000005595	inpp5d	98	54.852	Mola_mola
ENSG00000168918	INPP5D	89	90.944	ENSMODG00000010448	INPP5D	100	86.288	Monodelphis_domestica
ENSG00000168918	INPP5D	98	56.695	ENSMALG00000016456	inpp5d	98	56.647	Monopterus_albus
ENSG00000168918	INPP5D	100	87.280	MGP_CAROLIEiJ_G0014384	Inpp5d	100	92.694	Mus_caroli
ENSG00000168918	INPP5D	100	87.448	ENSMUSG00000026288	Inpp5d	100	92.998	Mus_musculus
ENSG00000168918	INPP5D	100	87.782	MGP_PahariEiJ_G0027621	Inpp5d	99	91.603	Mus_pahari
ENSG00000168918	INPP5D	100	87.531	MGP_SPRETEiJ_G0015186	Inpp5d	99	91.276	Mus_spretus
ENSG00000168918	INPP5D	100	88.629	ENSMPUG00000005289	INPP5D	100	88.712	Mustela_putorius_furo
ENSG00000168918	INPP5D	100	87.317	ENSMLUG00000017391	INPP5D	99	88.240	Myotis_lucifugus
ENSG00000168918	INPP5D	100	87.699	ENSNGAG00000015967	Inpp5d	96	87.699	Nannospalax_galili
ENSG00000168918	INPP5D	99	56.061	ENSNBRG00000012987	inpp5d	99	56.149	Neolamprologus_brichardi
ENSG00000168918	INPP5D	100	95.185	ENSNLEG00000008201	INPP5D	92	89.310	Nomascus_leucogenys
ENSG00000168918	INPP5D	60	93.981	ENSMEUG00000002891	-	73	93.548	Notamacropus_eugenii
ENSG00000168918	INPP5D	100	86.994	ENSOPRG00000014301	INPP5D	92	86.135	Ochotona_princeps
ENSG00000168918	INPP5D	100	84.790	ENSODEG00000008216	INPP5D	97	84.790	Octodon_degus
ENSG00000168918	INPP5D	99	56.780	ENSONIG00000019319	inpp5d	96	66.460	Oreochromis_niloticus
ENSG00000168918	INPP5D	99	55.556	ENSORLG00000015584	inpp5d	98	53.943	Oryzias_latipes
ENSG00000168918	INPP5D	99	55.556	ENSORLG00020020270	inpp5d	98	53.775	Oryzias_latipes_hni
ENSG00000168918	INPP5D	99	55.597	ENSORLG00015000466	inpp5d	98	54.177	Oryzias_latipes_hsok
ENSG00000168918	INPP5D	99	54.348	ENSOMEG00000002876	inpp5d	94	55.145	Oryzias_melastigma
ENSG00000168918	INPP5D	100	87.605	ENSOGAG00000009128	INPP5D	100	87.605	Otolemur_garnettii
ENSG00000168918	INPP5D	100	87.195	ENSOARG00000019324	INPP5D	100	87.844	Ovis_aries
ENSG00000168918	INPP5D	100	99.753	ENSPPAG00000030895	INPP5D	100	99.664	Pan_paniscus
ENSG00000168918	INPP5D	100	90.268	ENSPPRG00000011130	INPP5D	100	90.268	Panthera_pardus
ENSG00000168918	INPP5D	87	90.154	ENSPTIG00000009805	INPP5D	94	90.154	Panthera_tigris_altaica
ENSG00000168918	INPP5D	100	99.753	ENSPTRG00000013050	INPP5D	100	99.579	Pan_troglodytes
ENSG00000168918	INPP5D	100	97.778	ENSPANG00000019973	INPP5D	100	97.727	Papio_anubis
ENSG00000168918	INPP5D	98	57.736	ENSPKIG00000025393	inpp5d	98	54.684	Paramormyrops_kingsleyae
ENSG00000168918	INPP5D	99	71.359	ENSPSIG00000002173	INPP5D	99	70.008	Pelodiscus_sinensis
ENSG00000168918	INPP5D	82	69.940	ENSPMGG00000018491	inpp5d	86	64.384	Periophthalmus_magnuspinnatus
ENSG00000168918	INPP5D	100	87.026	ENSPEMG00000007040	Inpp5d	99	84.127	Peromyscus_maniculatus_bairdii
ENSG00000168918	INPP5D	99	55.800	ENSPFOG00000021881	inpp5d	98	55.424	Poecilia_formosa
ENSG00000168918	INPP5D	99	54.963	ENSPLAG00000017156	inpp5d	98	54.286	Poecilia_latipinna
ENSG00000168918	INPP5D	99	55.461	ENSPMEG00000019565	inpp5d	98	55.085	Poecilia_mexicana
ENSG00000168918	INPP5D	99	55.265	ENSPREG00000016395	inpp5d	96	55.068	Poecilia_reticulata
ENSG00000168918	INPP5D	100	99.136	ENSPPYG00000013288	INPP5D	100	87.805	Pongo_abelii
ENSG00000168918	INPP5D	88	87.573	ENSPCAG00000007196	INPP5D	86	87.573	Procavia_capensis
ENSG00000168918	INPP5D	95	90.117	ENSPCOG00000018356	INPP5D	97	76.910	Propithecus_coquereli
ENSG00000168918	INPP5D	87	90.645	ENSPVAG00000007918	INPP5D	83	90.064	Pteropus_vampyrus
ENSG00000168918	INPP5D	99	56.551	ENSPNYG00000019357	inpp5d	98	56.345	Pundamilia_nyererei
ENSG00000168918	INPP5D	98	55.481	ENSPNAG00000027826	inpp5d	97	58.365	Pygocentrus_nattereri
ENSG00000168918	INPP5D	100	87.605	ENSRNOG00000017020	Inpp5d	99	87.605	Rattus_norvegicus
ENSG00000168918	INPP5D	100	95.711	ENSRBIG00000033999	INPP5D	99	95.711	Rhinopithecus_bieti
ENSG00000168918	INPP5D	100	97.654	ENSRROG00000030416	INPP5D	100	97.475	Rhinopithecus_roxellana
ENSG00000168918	INPP5D	100	95.122	ENSSBOG00000028279	INPP5D	100	95.122	Saimiri_boliviensis_boliviensis
ENSG00000168918	INPP5D	99	58.220	ENSSFOG00015006629	inpp5d	98	57.637	Scleropages_formosus
ENSG00000168918	INPP5D	99	56.287	ENSSMAG00000001138	inpp5d	98	55.452	Scophthalmus_maximus
ENSG00000168918	INPP5D	99	55.788	ENSSDUG00000021622	inpp5d	99	54.937	Seriola_dumerili
ENSG00000168918	INPP5D	98	55.234	ENSSLDG00000002786	inpp5d	98	54.825	Seriola_lalandi_dorsalis
ENSG00000168918	INPP5D	85	86.420	ENSSPUG00000014342	INPP5D	96	73.903	Sphenodon_punctatus
ENSG00000168918	INPP5D	99	56.242	ENSSPAG00000016922	inpp5d	99	55.612	Stegastes_partitus
ENSG00000168918	INPP5D	100	88.070	ENSSSCG00000016298	INPP5D	100	88.401	Sus_scrofa
ENSG00000168918	INPP5D	99	70.037	ENSTGUG00000007342	INPP5D	99	69.554	Taeniopygia_guttata
ENSG00000168918	INPP5D	99	55.970	ENSTRUG00000001313	inpp5d	98	54.645	Takifugu_rubripes
ENSG00000168918	INPP5D	96	81.467	ENSTTRG00000016300	INPP5D	88	81.467	Tursiops_truncatus
ENSG00000168918	INPP5D	100	87.621	ENSUAMG00000027664	INPP5D	95	88.519	Ursus_americanus
ENSG00000168918	INPP5D	92	88.616	ENSUMAG00000014489	INPP5D	97	88.838	Ursus_maritimus
ENSG00000168918	INPP5D	100	89.121	ENSVVUG00000025476	INPP5D	100	89.121	Vulpes_vulpes
ENSG00000168918	INPP5D	86	60.038	ENSXETG00000013875	inpp5d	99	60.670	Xenopus_tropicalis
ENSG00000168918	INPP5D	98	55.499	ENSXMAG00000016471	inpp5d	98	55.143	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0004445	inositol-polyphosphate 5-phosphatase activity	8769125.	TAS	Function
GO:0005515	protein binding	9148918.10382761.15090612.16339535.19843936.20933011.21712384.24642916.25416956.26221972.26755705.	IPI	Function
GO:0005829	cytosol	-	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0005856	cytoskeleton	-	IEA	Component
GO:0005886	plasma membrane	-	IEA	Component
GO:0006661	phosphatidylinositol biosynthetic process	-	TAS	Process
GO:0006796	phosphate-containing compound metabolic process	8769125.	TAS	Process
GO:0006915	apoptotic process	-	IEA	Process
GO:0007165	signal transduction	8769125.	TAS	Process
GO:0008340	determination of adult lifespan	-	IEA	Process
GO:0009968	negative regulation of signal transduction	-	IEA	Process
GO:0016064	immunoglobulin mediated immune response	-	IEA	Process
GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity	-	TAS	Function
GO:0017124	SH3 domain binding	-	IEA	Function
GO:0019221	cytokine-mediated signaling pathway	-	TAS	Process
GO:0030889	negative regulation of B cell proliferation	-	IEA	Process
GO:0035556	intracellular signal transduction	-	IEA	Process
GO:0043065	positive regulation of apoptotic process	-	IEA	Process
GO:0043647	inositol phosphate metabolic process	-	TAS	Process
GO:0045121	membrane raft	-	IEA	Component
GO:0045409	negative regulation of interleukin-6 biosynthetic process	-	IEA	Process
GO:0045579	positive regulation of B cell differentiation	-	IEA	Process
GO:0045648	positive regulation of erythrocyte differentiation	-	IEA	Process
GO:0045656	negative regulation of monocyte differentiation	-	IEA	Process
GO:0045659	negative regulation of neutrophil differentiation	-	IEA	Process
GO:0045671	negative regulation of osteoclast differentiation	-	IEA	Process
GO:0045779	negative regulation of bone resorption	-	IEA	Process
GO:0046856	phosphatidylinositol dephosphorylation	-	IEA	Process
GO:0050777	negative regulation of immune response	-	IEA	Process
GO:0050852	T cell receptor signaling pathway	-	TAS	Process
GO:0050900	leukocyte migration	-	TAS	Process

EuRBPDB

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.