EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
20499681	[HINT1--a novel tumor suppressor protein of the HIT superfamily].	Postepy Biochem	2010	Ozga M	-
22647378	The tumor suppressor HINT1 regulates MITF and β-catenin transcriptional activity in melanoma cells.	Cell Cycle	2012 Jun 1	Genovese G	doi: 10.4161/cc.20765
21468541	Clinical significance of expression of Hint1 and potential epigenetic mechanism in gastric cancer.	Int J Oncol	2011 Jun	Huang H	doi: 10.3892/ijo.2011.994
24386364	Quantitative analysis of BTF3, HINT1, NDRG1 and ODC1 protein over-expression in human prostate cancer tissue.	PLoS One	2013 Dec 27	Symes AJ	doi: 10.1371/journal.pone.0084295

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr5	131165293	5'UTR	novel		0.57
BLCA	chr5	131165214	5'UTR	novel		0.97
CESC	chr5	131159544	Missense_Mutation	rs373197800	R95Q	0.34
CESC	chr5	131159558	Silent	NA	L90L	0.16
GBM	chr5	131162585	Missense_Mutation	novel	D68G	0.11	DcpS_C
GBM	chr5	131159588	Silent	novel	V80V	0.16
GBM	chr5	131159586	Missense_Mutation	novel	G81V	0.12
GBM	chr5	131159536	Missense_Mutation	novel	V98M	0.34
KIRP	chr5	131165152	Silent	NA	I18I	0.38
LAML	chr5	131162607	Missense_Mutation	novel	S61P	0.05	DcpS_C
LUAD	chr5	131165199	Missense_Mutation	novel	D3N	0.18
LUSC	chr5	131165113	Missense_Mutation	rs749444327	I31M	0.09	DcpS_C
OV	chr5	131165208	5'UTR	novel		0.07
SKCM	chr5	131162653	Silent	rs1802917	S45S	0.18
THCA	chr5	131159566	Missense_Mutation	rs753840070	L88V	0.37
UCEC	chr5	131159340	3'UTR	NA		0.39
UCEC	chr5	131162617	Missense_Mutation	NA	K57N	0.29	DcpS_C
UCEC	chr5	131159308	3'UTR	NA		0.33
UCEC	chr5	131159580	Missense_Mutation	novel	K83R	0.54
UCEC	chr5	131159336	3'UTR	novel		0.25
UCEC	chr5	131165172	Silent	novel	R12R	0.45
UCEC	chr5	131162630	Missense_Mutation	novel	L53R	0.33	DcpS_C
UCEC	chr5	131159533	Missense_Mutation	novel	N99D	0.32
UCEC	chr5	131159347	3'UTR	novel		0.59
UCEC	chr5	131159340	3'UTR	NA		0.35
UCEC	chr5	131162615	Missense_Mutation	novel	K58T	0.14	DcpS_C
UCEC	chr5	131159603	Silent	novel	G75G	0.47
UCEC	chr5	131159510	Silent	novel	Q106Q	0.2
UCEC	chr5	131162677	Splice_Site	NA	X38_splice	0.14
UCEC	chr5	131159308	3'UTR	novel		0.35
UCEC	chr5	131165082	Intron	novel		0.18

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
KIRP	DEL	0.0382	0.11554
LAML	DEL	0.0838	1.2971e-07
LUAD	DEL	0.3023	7.4776e-05
LUSC	DEL	0.6527	0.002071
MESO	DEL	0.1609	0.20184
PRAD	AMP	0.0264	0.16448
STAD	DEL	0.2721	2.8835e-08
THCA	AMP	0.0361	0.075436
THCA	DEL	0	0.23456

Survival Analysis

Cancer	P-value	Q-value
MESO	0.0011	Kaplan-Meier Survival Analysis
ESCA	0.043	Kaplan-Meier Survival Analysis
COAD	0.039	Kaplan-Meier Survival Analysis
LAML	0.0016	Kaplan-Meier Survival Analysis
KICH	0.0028	Kaplan-Meier Survival Analysis
UCEC	0.02	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000169567 (Gene tree)
Gene ID: 3094
Gene Symbol: HINT1
Alias: PKCI-1|PRKCNH1|HINT
Full Name: histidine triad nucleotide binding protein 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 12,709 bases
Position: chr5:131,159,027-131,171,735
Accession: 4912
RBP type: canonical RBP
Summary: This gene encodes a protein that hydrolyzes purine nucleotide phosphoramidates substrates, including AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif. This gene is considered a tumor suppressor gene. In addition, mutations in this gene can cause autosomal recessive neuromyotonia and axonal neuropathy. There are several related pseudogenes on chromosome 7. Several transcript variants have been observed. [provided by RefSeq, Dec 2015]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000304229	DcpS_C	PF11969.8	9e-22	1	1
ENSP00000427499	DcpS_C	PF11969.8	1.1e-11	1	1
ENSP00000426860	DcpS_C	PF11969.8	1.3e-11	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
18203262	Growth hormone action in the developing neural retina: a proteomic analysis.	Proteomics	2008 Jan	Baudet ML	doi: 10.1002/pmic.200700952.
14982931	Biochemical, crystallographic, and mutagenic characterization of hint, the AMP-lysine hydrolase, with novel substrates and inhibitors.	J Biol Chem	2004 Apr 30	Krakowiak A	-
22088864	Biological effects of the anti-parasitic chemotherapeutant emamectin benzoate on a non-target crustacean, the spot prawn (Pandalus platyceros Brandt, 1851) under laboratory conditions.	Aquat Toxicol	2012 Feb	Veldhoen N	doi: 10.1016/j.aquatox.2011.10.015

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000508488	HINT1-205	703	-	ENSP00000427499	103 (aa)	-	D6RD60
ENST00000511475	HINT1-207	923	-	ENSP00000427008	103 (aa)	-	D6RD60
ENST00000508495	HINT1-206	825	-	ENSP00000424974	78 (aa)	-	D6REP8
ENST00000504202	HINT1-202	619	-	ENSP00000425260	65 (aa)	-	D6RC06
ENST00000506908	HINT1-204	681	-	ENSP00000426860	78 (aa)	-	D6RE99
ENST00000513012	HINT1-208	583	-	ENSP00000422444	65 (aa)	-	D6RC06
ENST00000304043	HINT1-201	1081	-	ENSP00000304229	126 (aa)	-	P49773
ENST00000513345	HINT1-209	656	-	ENSP00000421608	65 (aa)	-	D6RC06
ENST00000520028	HINT1-210	82	-	ENSP00000430909	27 (aa)	-	H0YC49
ENST00000506207	HINT1-203	369	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000169567's gene model file

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000169567	rs202135714	5	131166104	CT	Blood protein levels	29875488	[0.19-0.31] unit increase	0.25	EFO_0007937

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000169567's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000169567	HINT1	100	72.222	ENSAPOG00000016821	HINT1	85	72.222	Acanthochromis_polyacanthus
ENSG00000169567	HINT1	100	96.825	ENSAMEG00000017774	HINT1	91	96.825	Ailuropoda_melanoleuca
ENSG00000169567	HINT1	100	73.810	ENSACIG00000009379	HINT1	100	73.810	Amphilophus_citrinellus
ENSG00000169567	HINT1	100	71.429	ENSAOCG00000005696	HINT1	85	71.429	Amphiprion_ocellaris
ENSG00000169567	HINT1	100	72.222	ENSAPEG00000003438	HINT1	85	72.222	Amphiprion_percula
ENSG00000169567	HINT1	100	74.603	ENSATEG00000010438	HINT1	100	74.603	Anabas_testudineus
ENSG00000169567	HINT1	71	80.899	ENSAPLG00000006365	HINT1	100	80.899	Anas_platyrhynchos
ENSG00000169567	HINT1	100	84.127	ENSACAG00000001424	HINT1	100	84.127	Anolis_carolinensis
ENSG00000169567	HINT1	93	83.761	ENSANAG00000010013	-	99	83.761	Aotus_nancymaae
ENSG00000169567	HINT1	100	89.744	ENSANAG00000019623	-	100	96.040	Aotus_nancymaae
ENSG00000169567	HINT1	100	98.413	ENSANAG00000002703	-	100	98.413	Aotus_nancymaae
ENSG00000169567	HINT1	100	73.016	ENSANAG00000029738	-	100	73.016	Aotus_nancymaae
ENSG00000169567	HINT1	96	72.727	ENSACLG00000023571	HINT1	99	72.727	Astatotilapia_calliptera
ENSG00000169567	HINT1	100	76.190	ENSAMXG00000039321	HINT1	100	76.190	Astyanax_mexicanus
ENSG00000169567	HINT1	100	93.651	ENSBTAG00000052700	-	100	93.651	Bos_taurus
ENSG00000169567	HINT1	100	83.333	ENSBTAG00000048002	-	96	87.368	Bos_taurus
ENSG00000169567	HINT1	100	94.444	ENSBTAG00000010959	HINT1	100	94.444	Bos_taurus
ENSG00000169567	HINT1	90	66.372	WBGene00009002	hint-1	87	66.372	Caenorhabditis_elegans
ENSG00000169567	HINT1	100	96.094	ENSCJAG00000043993	-	100	96.094	Callithrix_jacchus
ENSG00000169567	HINT1	100	99.206	ENSCJAG00000039525	-	100	99.206	Callithrix_jacchus
ENSG00000169567	HINT1	100	91.026	ENSCJAG00000009599	-	84	96.522	Callithrix_jacchus
ENSG00000169567	HINT1	100	99.206	ENSCJAG00000046852	-	100	99.206	Callithrix_jacchus
ENSG00000169567	HINT1	100	97.619	ENSCJAG00000039510	-	100	97.619	Callithrix_jacchus
ENSG00000169567	HINT1	94	90.411	ENSCAFG00000011182	-	99	80.800	Canis_familiaris
ENSG00000169567	HINT1	100	92.308	ENSCAFG00000032152	HINT1	99	97.000	Canis_familiaris
ENSG00000169567	HINT1	99	89.600	ENSCAFG00000005166	-	99	89.600	Canis_familiaris
ENSG00000169567	HINT1	97	91.803	ENSCAFG00020017446	-	100	91.803	Canis_lupus_dingo
ENSG00000169567	HINT1	100	89.744	ENSCAFG00020005075	-	100	94.624	Canis_lupus_dingo
ENSG00000169567	HINT1	97	89.344	ENSCAFG00020019228	-	98	89.344	Canis_lupus_dingo
ENSG00000169567	HINT1	98	89.516	ENSCAFG00020019227	-	93	89.516	Canis_lupus_dingo
ENSG00000169567	HINT1	97	96.053	ENSCAFG00020013588	HINT1	51	96.053	Canis_lupus_dingo
ENSG00000169567	HINT1	100	83.333	ENSCHIG00000009185	-	97	76.800	Capra_hircus
ENSG00000169567	HINT1	100	87.179	ENSCHIG00000011526	-	97	88.618	Capra_hircus
ENSG00000169567	HINT1	100	95.238	ENSCHIG00000018678	-	100	95.238	Capra_hircus
ENSG00000169567	HINT1	100	98.413	ENSTSYG00000009158	-	100	98.413	Carlito_syrichta
ENSG00000169567	HINT1	100	84.127	ENSTSYG00000025807	-	100	84.127	Carlito_syrichta
ENSG00000169567	HINT1	100	80.952	ENSTSYG00000032979	-	100	80.952	Carlito_syrichta
ENSG00000169567	HINT1	100	84.127	ENSTSYG00000031487	-	100	84.127	Carlito_syrichta
ENSG00000169567	HINT1	100	78.205	ENSTSYG00000029784	-	78	82.432	Carlito_syrichta
ENSG00000169567	HINT1	100	84.127	ENSTSYG00000034218	-	100	84.127	Carlito_syrichta
ENSG00000169567	HINT1	71	93.333	ENSCPOG00000023046	HINT1	87	93.333	Cavia_porcellus
ENSG00000169567	HINT1	97	90.789	ENSCCAG00000024935	-	85	90.789	Cebus_capucinus
ENSG00000169567	HINT1	100	98.413	ENSCCAG00000005518	HINT1	100	98.413	Cebus_capucinus
ENSG00000169567	HINT1	100	77.778	ENSCATG00000039088	-	100	77.778	Cercocebus_atys
ENSG00000169567	HINT1	100	99.206	ENSCATG00000037620	HINT1	100	99.206	Cercocebus_atys
ENSG00000169567	HINT1	71	96.629	ENSCLAG00000012693	HINT1	100	96.629	Chinchilla_lanigera
ENSG00000169567	HINT1	100	99.206	ENSCSAG00000014000	HINT1	100	99.206	Chlorocebus_sabaeus
ENSG00000169567	HINT1	100	87.302	ENSCPBG00000020313	HINT1	100	87.302	Chrysemys_picta_bellii
ENSG00000169567	HINT1	100	78.571	ENSCANG00000042266	-	100	78.571	Colobus_angolensis_palliatus
ENSG00000169567	HINT1	100	96.032	ENSCANG00000019645	-	100	96.032	Colobus_angolensis_palliatus
ENSG00000169567	HINT1	100	97.619	ENSCANG00000040976	-	100	97.619	Colobus_angolensis_palliatus
ENSG00000169567	HINT1	100	96.032	ENSCGRG00001023991	Hint1	100	96.032	Cricetulus_griseus_chok1gshd
ENSG00000169567	HINT1	67	100.000	ENSCGRG00000014274	Hint1	93	94.444	Cricetulus_griseus_crigri
ENSG00000169567	HINT1	100	96.032	ENSDNOG00000030844	HINT1	100	96.032	Dasypus_novemcinctus
ENSG00000169567	HINT1	98	73.984	ENSDORG00000024559	-	100	73.984	Dipodomys_ordii
ENSG00000169567	HINT1	81	87.255	ENSDORG00000024485	-	97	87.255	Dipodomys_ordii
ENSG00000169567	HINT1	96	80.992	ENSDORG00000011944	-	96	80.992	Dipodomys_ordii
ENSG00000169567	HINT1	100	92.857	ENSDORG00000029580	-	100	92.857	Dipodomys_ordii
ENSG00000169567	HINT1	100	92.308	ENSETEG00000010127	-	69	97.727	Echinops_telfairi
ENSG00000169567	HINT1	100	97.619	ENSETEG00000015133	-	100	97.619	Echinops_telfairi
ENSG00000169567	HINT1	100	92.857	ENSEEUG00000008175	HINT1	100	92.857	Erinaceus_europaeus
ENSG00000169567	HINT1	86	89.815	ENSFCAG00000025373	-	95	89.815	Felis_catus
ENSG00000169567	HINT1	100	96.825	ENSFCAG00000041137	-	100	96.825	Felis_catus
ENSG00000169567	HINT1	71	84.444	ENSFALG00000004845	HINT1	100	84.444	Ficedula_albicollis
ENSG00000169567	HINT1	74	92.473	ENSFDAG00000007061	HINT1	85	92.473	Fukomys_damarensis
ENSG00000169567	HINT1	100	82.540	ENSGALG00000048320	chPKCI	100	82.540	Gallus_gallus
ENSG00000169567	HINT1	100	74.603	ENSGACG00000010631	HINT1	100	74.603	Gasterosteus_aculeatus
ENSG00000169567	HINT1	100	86.508	ENSGAGG00000003907	HINT1	100	86.508	Gopherus_agassizii
ENSG00000169567	HINT1	100	100.000	ENSGGOG00000011967	HINT1	100	100.000	Gorilla_gorilla
ENSG00000169567	HINT1	100	89.683	ENSGGOG00000026448	-	100	89.683	Gorilla_gorilla
ENSG00000169567	HINT1	100	73.810	ENSHBUG00000013488	HINT1	100	73.810	Haplochromis_burtoni
ENSG00000169567	HINT1	100	97.619	ENSHGLG00000010996	HINT1	100	97.619	Heterocephalus_glaber_female
ENSG00000169567	HINT1	71	96.629	ENSHGLG00100007099	HINT1	75	96.629	Heterocephalus_glaber_male
ENSG00000169567	HINT1	100	76.190	ENSHCOG00000002161	HINT1	70	76.190	Hippocampus_comes
ENSG00000169567	HINT1	100	89.764	ENSSTOG00000027920	-	100	89.764	Ictidomys_tridecemlineatus
ENSG00000169567	HINT1	100	84.252	ENSSTOG00000034368	-	100	84.252	Ictidomys_tridecemlineatus
ENSG00000169567	HINT1	95	81.818	ENSSTOG00000028618	-	100	81.818	Ictidomys_tridecemlineatus
ENSG00000169567	HINT1	100	69.841	ENSKMAG00000003173	HINT1	100	69.841	Kryptolebias_marmoratus
ENSG00000169567	HINT1	100	73.016	ENSLBEG00000022872	HINT1	100	73.016	Labrus_bergylta
ENSG00000169567	HINT1	100	73.016	ENSLBEG00000007882	-	100	73.016	Labrus_bergylta
ENSG00000169567	HINT1	100	68.254	ENSLACG00000015723	-	100	68.254	Latimeria_chalumnae
ENSG00000169567	HINT1	91	79.130	ENSLACG00000012554	HINT1	97	79.130	Latimeria_chalumnae
ENSG00000169567	HINT1	100	76.190	ENSLOCG00000008277	HINT1	100	76.190	Lepisosteus_oculatus
ENSG00000169567	HINT1	100	84.252	ENSLAFG00000027903	HINT1	100	84.252	Loxodonta_africana
ENSG00000169567	HINT1	100	78.571	ENSMFAG00000032836	-	100	78.571	Macaca_fascicularis
ENSG00000169567	HINT1	100	99.206	ENSMFAG00000036310	HINT1	100	99.206	Macaca_fascicularis
ENSG00000169567	HINT1	100	78.571	ENSMMUG00000046053	-	100	78.571	Macaca_mulatta
ENSG00000169567	HINT1	100	99.206	ENSMMUG00000009985	HINT1	100	99.206	Macaca_mulatta
ENSG00000169567	HINT1	100	76.984	ENSMNEG00000006813	-	100	76.984	Macaca_nemestrina
ENSG00000169567	HINT1	100	97.619	ENSMNEG00000034414	HINT1	100	97.619	Macaca_nemestrina
ENSG00000169567	HINT1	100	80.159	ENSMLEG00000031369	-	100	80.159	Mandrillus_leucophaeus
ENSG00000169567	HINT1	100	99.206	ENSMLEG00000039600	HINT1	100	99.206	Mandrillus_leucophaeus
ENSG00000169567	HINT1	100	72.222	ENSMAMG00000021815	HINT1	100	72.222	Mastacembelus_armatus
ENSG00000169567	HINT1	100	73.016	ENSMZEG00005027384	HINT1	100	73.016	Maylandia_zebra
ENSG00000169567	HINT1	75	80.000	ENSMGAG00000006655	HINT1	100	80.000	Meleagris_gallopavo
ENSG00000169567	HINT1	71	93.258	ENSMAUG00000003917	Hint1	100	93.258	Mesocricetus_auratus
ENSG00000169567	HINT1	100	96.825	ENSMICG00000035584	HINT1	100	96.825	Microcebus_murinus
ENSG00000169567	HINT1	100	94.444	ENSMOCG00000015219	Hint1	100	94.444	Microtus_ochrogaster
ENSG00000169567	HINT1	100	87.302	ENSMODG00000028727	-	100	87.302	Monodelphis_domestica
ENSG00000169567	HINT1	100	79.487	ENSMODG00000024687	-	99	80.165	Monodelphis_domestica
ENSG00000169567	HINT1	88	73.874	ENSMODG00000023571	-	90	73.874	Monodelphis_domestica
ENSG00000169567	HINT1	100	96.154	MGP_CAROLIEiJ_G0016362	Hint1	100	94.444	Mus_caroli
ENSG00000169567	HINT1	100	96.154	ENSMUSG00000020267	Hint1	100	94.444	Mus_musculus
ENSG00000169567	HINT1	100	96.154	MGP_PahariEiJ_G0017497	Hint1	100	94.444	Mus_pahari
ENSG00000169567	HINT1	100	96.154	MGP_SPRETEiJ_G0017204	Hint1	99	96.154	Mus_spretus
ENSG00000169567	HINT1	100	94.444	ENSMPUG00000018954	-	100	94.444	Mustela_putorius_furo
ENSG00000169567	HINT1	100	96.825	ENSMPUG00000011639	-	93	96.825	Mustela_putorius_furo
ENSG00000169567	HINT1	100	95.238	ENSMPUG00000018741	-	100	95.238	Mustela_putorius_furo
ENSG00000169567	HINT1	100	92.857	ENSMPUG00000018851	-	100	92.857	Mustela_putorius_furo
ENSG00000169567	HINT1	85	76.636	ENSMLUG00000025247	-	100	76.636	Myotis_lucifugus
ENSG00000169567	HINT1	100	95.238	ENSMLUG00000001091	HINT1	77	95.238	Myotis_lucifugus
ENSG00000169567	HINT1	100	95.238	ENSNGAG00000016071	Hint1	100	95.238	Nannospalax_galili
ENSG00000169567	HINT1	100	73.810	ENSNBRG00000013475	HINT1	100	73.810	Neolamprologus_brichardi
ENSG00000169567	HINT1	100	97.619	ENSNLEG00000012431	HINT1	100	97.619	Nomascus_leucogenys
ENSG00000169567	HINT1	99	81.818	ENSNLEG00000032105	-	100	76.190	Nomascus_leucogenys
ENSG00000169567	HINT1	100	87.302	ENSMEUG00000005368	-	100	87.302	Notamacropus_eugenii
ENSG00000169567	HINT1	99	96.000	ENSODEG00000020071	-	99	96.000	Octodon_degus
ENSG00000169567	HINT1	100	85.897	ENSODEG00000001529	-	88	89.286	Octodon_degus
ENSG00000169567	HINT1	71	97.753	ENSODEG00000008456	-	100	97.753	Octodon_degus
ENSG00000169567	HINT1	100	94.444	ENSODEG00000020080	-	100	94.444	Octodon_degus
ENSG00000169567	HINT1	100	73.810	ENSONIG00000000901	HINT1	100	73.810	Oreochromis_niloticus
ENSG00000169567	HINT1	100	96.032	ENSOCUG00000006607	HINT1	100	96.032	Oryctolagus_cuniculus
ENSG00000169567	HINT1	100	93.651	ENSOCUG00000008405	-	100	93.651	Oryctolagus_cuniculus
ENSG00000169567	HINT1	100	73.810	ENSORLG00000004689	HINT1	80	73.810	Oryzias_latipes
ENSG00000169567	HINT1	100	73.016	ENSORLG00020012355	HINT1	100	73.016	Oryzias_latipes_hni
ENSG00000169567	HINT1	100	73.016	ENSORLG00015000493	HINT1	80	73.016	Oryzias_latipes_hsok
ENSG00000169567	HINT1	100	71.429	ENSOMEG00000011624	HINT1	100	71.429	Oryzias_melastigma
ENSG00000169567	HINT1	100	97.619	ENSOGAG00000008850	HINT1	100	97.619	Otolemur_garnettii
ENSG00000169567	HINT1	100	96.032	ENSOARG00000017230	-	100	96.032	Ovis_aries
ENSG00000169567	HINT1	74	95.699	ENSOARG00000016673	-	76	95.699	Ovis_aries
ENSG00000169567	HINT1	100	100.000	ENSPPAG00000039560	HINT1	100	100.000	Pan_paniscus
ENSG00000169567	HINT1	100	87.302	ENSPPAG00000019786	-	79	87.302	Pan_paniscus
ENSG00000169567	HINT1	85	93.458	ENSPPRG00000005370	-	83	93.458	Panthera_pardus
ENSG00000169567	HINT1	100	96.032	ENSPPRG00000002010	-	100	96.032	Panthera_pardus
ENSG00000169567	HINT1	71	97.753	ENSPTIG00000014418	-	98	97.753	Panthera_tigris_altaica
ENSG00000169567	HINT1	85	91.589	ENSPTIG00000004092	-	83	91.589	Panthera_tigris_altaica
ENSG00000169567	HINT1	100	100.000	ENSPTRG00000017206	HINT1	100	100.000	Pan_troglodytes
ENSG00000169567	HINT1	100	87.302	ENSPTRG00000044233	-	79	87.302	Pan_troglodytes
ENSG00000169567	HINT1	100	87.302	ENSPTRG00000044680	-	79	87.302	Pan_troglodytes
ENSG00000169567	HINT1	100	78.571	ENSPANG00000030144	-	100	78.571	Papio_anubis
ENSG00000169567	HINT1	100	99.206	ENSPANG00000012466	HINT1	100	99.206	Papio_anubis
ENSG00000169567	HINT1	100	86.508	ENSPSIG00000016850	HINT1	100	86.508	Pelodiscus_sinensis
ENSG00000169567	HINT1	100	70.635	ENSPMGG00000013207	HINT1	100	70.635	Periophthalmus_magnuspinnatus
ENSG00000169567	HINT1	100	69.231	ENSPCIG00000013313	-	88	75.248	Phascolarctos_cinereus
ENSG00000169567	HINT1	100	78.205	ENSPCIG00000014188	-	100	84.043	Phascolarctos_cinereus
ENSG00000169567	HINT1	97	86.992	ENSPCIG00000024152	-	98	86.992	Phascolarctos_cinereus
ENSG00000169567	HINT1	100	88.889	ENSPCIG00000029889	-	100	88.889	Phascolarctos_cinereus
ENSG00000169567	HINT1	100	99.206	ENSPPYG00000015747	HINT1	100	99.206	Pongo_abelii
ENSG00000169567	HINT1	100	97.619	ENSPCAG00000004737	HINT1	100	97.619	Procavia_capensis
ENSG00000169567	HINT1	100	73.016	ENSPNYG00000001225	HINT1	100	73.016	Pundamilia_nyererei
ENSG00000169567	HINT1	100	76.984	ENSPNAG00000020038	HINT1	100	76.984	Pygocentrus_nattereri
ENSG00000169567	HINT1	100	94.444	ENSRNOG00000000622	Hint1	100	94.444	Rattus_norvegicus
ENSG00000169567	HINT1	100	93.651	ENSRNOG00000005630	AABR07060778.1	100	93.651	Rattus_norvegicus
ENSG00000169567	HINT1	100	77.778	ENSRBIG00000035719	-	100	77.778	Rhinopithecus_bieti
ENSG00000169567	HINT1	100	98.413	ENSRBIG00000021800	HINT1	100	98.413	Rhinopithecus_bieti
ENSG00000169567	HINT1	100	77.778	ENSRROG00000032299	-	100	77.778	Rhinopithecus_roxellana
ENSG00000169567	HINT1	100	98.413	ENSRROG00000024779	HINT1	100	98.413	Rhinopithecus_roxellana
ENSG00000169567	HINT1	91	75.652	ENSSBOG00000036086	-	99	75.652	Saimiri_boliviensis_boliviensis
ENSG00000169567	HINT1	100	94.872	ENSSBOG00000019209	-	100	94.872	Saimiri_boliviensis_boliviensis
ENSG00000169567	HINT1	100	91.270	ENSSBOG00000032726	-	100	91.270	Saimiri_boliviensis_boliviensis
ENSG00000169567	HINT1	100	87.179	ENSSBOG00000031899	-	100	83.333	Saimiri_boliviensis_boliviensis
ENSG00000169567	HINT1	100	71.795	ENSSBOG00000023204	-	100	69.841	Saimiri_boliviensis_boliviensis
ENSG00000169567	HINT1	97	95.902	ENSSBOG00000015921	-	100	95.902	Saimiri_boliviensis_boliviensis
ENSG00000169567	HINT1	100	89.683	ENSSHAG00000005834	-	100	89.683	Sarcophilus_harrisii
ENSG00000169567	HINT1	100	74.603	ENSSFOG00015007779	hint1	100	74.603	Scleropages_formosus
ENSG00000169567	HINT1	100	78.571	ENSSDUG00000018899	HINT1	100	78.571	Seriola_dumerili
ENSG00000169567	HINT1	100	78.571	ENSSLDG00000022907	HINT1	100	78.571	Seriola_lalandi_dorsalis
ENSG00000169567	HINT1	100	84.127	ENSSPUG00000012327	HINT1	100	84.127	Sphenodon_punctatus
ENSG00000169567	HINT1	100	73.016	ENSSPAG00000014003	HINT1	100	73.016	Stegastes_partitus
ENSG00000169567	HINT1	100	95.238	ENSSSCG00000014264	-	100	95.238	Sus_scrofa
ENSG00000169567	HINT1	100	67.460	ENSSSCG00000001060	-	100	67.460	Sus_scrofa
ENSG00000169567	HINT1	100	84.921	ENSTGUG00000000395	HINT1	100	84.921	Taeniopygia_guttata
ENSG00000169567	HINT1	100	76.190	ENSTNIG00000007475	HINT1	100	76.190	Tetraodon_nigroviridis
ENSG00000169567	HINT1	71	96.629	ENSTBEG00000001666	HINT1	100	96.629	Tupaia_belangeri
ENSG00000169567	HINT1	100	94.444	ENSTTRG00000008653	HINT1	100	94.444	Tursiops_truncatus
ENSG00000169567	HINT1	100	96.825	ENSUAMG00000026418	HINT1	100	96.825	Ursus_americanus
ENSG00000169567	HINT1	100	71.795	ENSUMAG00000004250	-	61	75.000	Ursus_maritimus
ENSG00000169567	HINT1	92	95.833	ENSVPAG00000004473	HINT1	58	95.833	Vicugna_pacos
ENSG00000169567	HINT1	97	96.053	ENSVVUG00000029183	HINT1	52	96.053	Vulpes_vulpes
ENSG00000169567	HINT1	83	87.692	ENSVVUG00000021634	-	58	75.000	Vulpes_vulpes
ENSG00000169567	HINT1	100	87.179	ENSVVUG00000008123	-	100	89.344	Vulpes_vulpes
ENSG00000169567	HINT1	90	92.105	ENSVVUG00000013171	-	90	92.105	Vulpes_vulpes
ENSG00000169567	HINT1	100	77.778	ENSXETG00000008278	hint1	100	77.778	Xenopus_tropicalis

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000118	histone deacetylase complex	16835243.	IDA	Component
GO:0000166	nucleotide binding	-	IEA	Function
GO:0005080	protein kinase C binding	9770345.	TAS	Function
GO:0005634	nucleus	-	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005856	cytoskeleton	8812426.	TAS	Component
GO:0005886	plasma membrane	-	IDA	Component
GO:0006355	regulation of transcription, DNA-templated	16835243.	IMP	Process
GO:0007165	signal transduction	8812426.	TAS	Process
GO:0009154	purine ribonucleotide catabolic process	16835243.	IDA	Process
GO:0016787	hydrolase activity	16835243.	IDA	Function
GO:0050850	positive regulation of calcium-mediated signaling	-	IEA	Process
GO:0070062	extracellular exosome	19056867.20458337.	HDA	Component
GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	16835243.	IMP	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

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Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

GWAS

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.