Cancer | Chr | Position | Mutation Type | dbSNP | Protein-change | Allele Freq | RBD |
---|---|---|---|---|---|---|---|
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BRCA | |||||||
BRCA | |||||||
CESC | |||||||
CESC | |||||||
CESC | |||||||
CESC | |||||||
CHOL | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
DLBC | |||||||
DLBC | |||||||
ESCA | |||||||
GBM | |||||||
GBM | |||||||
HNSC | |||||||
HNSC | |||||||
KIRP | |||||||
LIHC | |||||||
LIHC | |||||||
LIHC | |||||||
LUAD | |||||||
LUAD | |||||||
LUSC | |||||||
LUSC | |||||||
LUSC | |||||||
LUSC | |||||||
LUSC | |||||||
LUSC | |||||||
LUSC | |||||||
MESO | |||||||
MESO | |||||||
OV | |||||||
OV | |||||||
PAAD | |||||||
PRAD | |||||||
SARC | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC |
Cancer | Type | Freq | Q-value |
---|---|---|---|
ESCA | |||
PRAD | |||
TGCT |
Cancer | P-value | Q-value |
---|---|---|
THYM | ||
MESO | ||
ACC | ||
PAAD | ||
PCPG | ||
CESC | ||
LAML | ||
LIHC | ||
LGG | ||
THCA | ||
UVM | ||
OV |
Transcript ID | Name | Length | RefSeq ID | Protein ID | Length | RefSeq ID | UniportKB ID |
---|---|---|---|---|---|---|---|
ENST00000529724 | PPP1CA-206 | 572 | - | - | - (aa) | - | - |
ENST00000358239 | PPP1CA-202 | 1054 | - | ENSP00000350974 | 286 (aa) | - | P62136 |
ENST00000526510 | PPP1CA-204 | 1677 | - | - | - (aa) | - | - |
ENST00000312989 | PPP1CA-201 | 1389 | - | ENSP00000326031 | 341 (aa) | - | P62136 |
ENST00000537694 | PPP1CA-209 | 882 | - | - | - (aa) | - | - |
ENST00000546202 | PPP1CA-211 | 554 | - | ENSP00000439568 | 169 (aa) | - | F5H1L6 |
ENST00000527663 | PPP1CA-205 | 765 | - | ENSP00000431146 | 253 (aa) | - | E9PMD7 |
ENST00000532279 | PPP1CA-207 | 552 | - | - | - (aa) | - | - |
ENST00000542876 | PPP1CA-210 | 588 | - | ENSP00000438409 | 179 (aa) | - | F5H037 |
ENST00000376745 | PPP1CA-203 | 1476 | - | ENSP00000365936 | 330 (aa) | - | P62136 |
ENST00000532446 | PPP1CA-208 | 1465 | - | - | - (aa) | - | - |
Pathway ID | Pathway Name | Source |
---|---|---|
hsa03015 | mRNA surveillance pathway | KEGG |
hsa04022 | cGMP-PKG signaling pathway | KEGG |
hsa04024 | cAMP signaling pathway | KEGG |
hsa04114 | Oocyte meiosis | KEGG |
hsa04218 | Cellular senescence | KEGG |
hsa04261 | Adrenergic signaling in cardiomyocytes | KEGG |
hsa04270 | Vascular smooth muscle contraction | KEGG |
hsa04390 | Hippo signaling pathway | KEGG |
hsa04510 | Focal adhesion | KEGG |
hsa04611 | Platelet activation | KEGG |
hsa04720 | Long-term potentiation | KEGG |
hsa04728 | Dopaminergic synapse | KEGG |
hsa04750 | Inflammatory mediator regulation of TRP channels | KEGG |
hsa04810 | Regulation of actin cytoskeleton | KEGG |
hsa04910 | Insulin signaling pathway | KEGG |
hsa04921 | Oxytocin signaling pathway | KEGG |
hsa04931 | Insulin resistance | KEGG |
hsa05031 | Amphetamine addiction | KEGG |
hsa05034 | Alcoholism | KEGG |
hsa05168 | Herpes simplex virus 1 infection | KEGG |
hsa05205 | Proteoglycans in cancer | KEGG |
ensgID | SNP | Chromosome | Position | SNP-risk | Trait | PubmedID | 95% CI | Or or BEAT | EFO ID |
---|---|---|---|---|---|---|---|---|---|
ENSG00000172531 | rs61734601 | 11 | 67417254 | A | Height | 28270201 | [0.0054-0.0102] m decrease | 0.007811173 | EFO_0004339 |
Ensembl ID | Gene Symbol | Coverage | Identiy | Ortholog | Gene Symbol | Coverage | Identiy | Species |
---|---|---|---|---|---|---|---|---|
ENSG00000172531 | PPP1CA | 90 | 93.603 | FBgn0004103 | Pp1-87B | 98 | 93.603 | Drosophila_melanogaster |
ENSG00000172531 | PPP1CA | 100 | 90.663 | ENSG00000186298 | PPP1CC | 100 | 94.286 | Homo_sapiens |
ENSG00000172531 | PPP1CA | 100 | 99.697 | ENSMUSG00000040385 | Ppp1ca | 100 | 99.697 | Mus_musculus |
Go ID | Go_term | PubmedID | Evidence | Category |
---|---|---|---|---|
GO:0000164 | protein phosphatase type 1 complex | - | IEA | Component |
GO:0000784 | nuclear chromosome, telomeric region | 24270157. | IDA | Component |
GO:0004721 | phosphoprotein phosphatase activity | - | ISS | Function |
GO:0004722 | protein serine/threonine phosphatase activity | 21873635. | IBA | Function |
GO:0004722 | protein serine/threonine phosphatase activity | 10640627.16262633. | TAS | Function |
GO:0005515 | protein binding | 10807923.11739654.12434308.15231748.16263087.16732323.17274640.17318175.17511879.17965019.18068675.18842582.19389623.20186153.20305656.20424263.20467437.20516061.20826336.20926688.21094159.21382349.21518769.21666598.21998301.22321011.22365833.22940584.23396208.23555304.23937259.24366813.25416956.25544563.25593058.25785436.27173435.28330616.29109149. | IPI | Function |
GO:0005634 | nucleus | 21630459. | HDA | Component |
GO:0005634 | nucleus | 21873635. | IBA | Component |
GO:0005634 | nucleus | 11739654. | IDA | Component |
GO:0005654 | nucleoplasm | - | IDA | Component |
GO:0005730 | nucleolus | - | IEA | Component |
GO:0005737 | cytoplasm | 21873635. | IBA | Component |
GO:0005737 | cytoplasm | 11739654. | IDA | Component |
GO:0005829 | cytosol | - | IDA | Component |
GO:0005829 | cytosol | - | TAS | Component |
GO:0005886 | plasma membrane | - | IDA | Component |
GO:0005913 | cell-cell adherens junction | 25468996. | IDA | Component |
GO:0005977 | glycogen metabolic process | - | IEA | Process |
GO:0005979 | regulation of glycogen biosynthetic process | - | IEA | Process |
GO:0005981 | regulation of glycogen catabolic process | - | IEA | Process |
GO:0006470 | protein dephosphorylation | 22311981.22801782. | IMP | Process |
GO:0006470 | protein dephosphorylation | - | ISS | Process |
GO:0007049 | cell cycle | - | IEA | Process |
GO:0008157 | protein phosphatase 1 binding | 21873635. | IBA | Function |
GO:0010288 | response to lead ion | - | ISS | Process |
GO:0016311 | dephosphorylation | 22311981. | IDA | Process |
GO:0016791 | phosphatase activity | - | ISS | Function |
GO:0030324 | lung development | - | IEA | Process |
GO:0032091 | negative regulation of protein binding | - | ISS | Process |
GO:0032922 | circadian regulation of gene expression | - | ISS | Process |
GO:0035970 | peptidyl-threonine dephosphorylation | 16262633. | TAS | Process |
GO:0036496 | regulation of translational initiation by eIF2 alpha dephosphorylation | - | ISS | Process |
GO:0042587 | glycogen granule | - | IEA | Component |
GO:0042752 | regulation of circadian rhythm | 21873635. | IBA | Process |
GO:0042752 | regulation of circadian rhythm | 21712997. | IMP | Process |
GO:0043021 | ribonucleoprotein complex binding | - | IEA | Function |
GO:0043153 | entrainment of circadian clock by photoperiod | 21873635. | IBA | Process |
GO:0043153 | entrainment of circadian clock by photoperiod | - | ISS | Process |
GO:0043197 | dendritic spine | - | IEA | Component |
GO:0043204 | perikaryon | - | IEA | Component |
GO:0046872 | metal ion binding | - | IEA | Function |
GO:0048754 | branching morphogenesis of an epithelial tube | - | IEA | Process |
GO:0051301 | cell division | - | IEA | Process |
GO:0060828 | regulation of canonical Wnt signaling pathway | 17318175. | IC | Process |
GO:0070062 | extracellular exosome | 20458337. | HDA | Component |
GO:0070262 | peptidyl-serine dephosphorylation | 16262633. | TAS | Process |
GO:0072357 | PTW/PP1 phosphatase complex | 20516061. | IDA | Component |
GO:0098609 | cell-cell adhesion | - | IEA | Process |
GO:0098641 | cadherin binding involved in cell-cell adhesion | 25468996. | IDA | Function |
GO:0098793 | presynapse | - | IEA | Component |
GO:0098978 | glutamatergic synapse | - | IEA | Component |
GO:1904886 | beta-catenin destruction complex disassembly | - | ISS | Process |
GO:2001241 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand | - | IEA | Process |