Cancer | Chr | Position | Mutation Type | dbSNP | Protein-change | Allele Freq | RBD |
---|---|---|---|---|---|---|---|
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BRCA | |||||||
BRCA | |||||||
BRCA | |||||||
BRCA | |||||||
CESC | |||||||
CESC | |||||||
CESC | |||||||
CESC | |||||||
CESC | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
GBM | |||||||
GBM | |||||||
HNSC | |||||||
HNSC | |||||||
KIRC | |||||||
KIRP | |||||||
KIRP | |||||||
LAML | |||||||
LGG | |||||||
LIHC | |||||||
LUAD | |||||||
LUAD | |||||||
LUAD | |||||||
LUAD | |||||||
LUAD | |||||||
LUAD | |||||||
LUSC | |||||||
OV | |||||||
PAAD | |||||||
PRAD | |||||||
SARC | |||||||
SARC | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC |
Cancer | Type | Freq | Q-value |
---|---|---|---|
BRCA | |||
ESCA | |||
TGCT |
Cancer | P-value | Q-value |
---|---|---|
KIRC | ||
STAD | ||
SKCM | ||
BRCA | ||
ESCA | ||
KIRP | ||
PAAD | ||
UCEC | ||
LGG | ||
LUAD | ||
UVM |
Protein ID | Domain | Pfam ID | E-value | Domain number | Total number |
---|---|---|---|---|---|
ENSP00000434220 | zf-C2H2 | PF00096.26 | 1.2e-13 | 1 | 3 |
ENSP00000434220 | zf-C2H2 | PF00096.26 | 1.2e-13 | 2 | 3 |
ENSP00000434220 | zf-C2H2 | PF00096.26 | 1.2e-13 | 3 | 3 |
ENSP00000337862 | zf-C2H2 | PF00096.26 | 3.7e-13 | 1 | 3 |
ENSP00000337862 | zf-C2H2 | PF00096.26 | 3.7e-13 | 2 | 3 |
ENSP00000337862 | zf-C2H2 | PF00096.26 | 3.7e-13 | 3 | 3 |
ENSP00000434220 | zf-met | PF12874.7 | 0.0005 | 1 | 2 |
ENSP00000434220 | zf-met | PF12874.7 | 0.0005 | 2 | 2 |
ENSP00000337862 | zf-met | PF12874.7 | 0.0015 | 1 | 2 |
ENSP00000337862 | zf-met | PF12874.7 | 0.0015 | 2 | 2 |
Transcript ID | Name | Length | RefSeq ID | Protein ID | Length | RefSeq ID | UniportKB ID |
---|---|---|---|---|---|---|---|
ENST00000532448 | OVOL1-203 | 1774 | XM_005274018 | ENSP00000434220 | 205 (aa) | XP_005274075 | G3V1B0 |
ENST00000531907 | OVOL1-202 | 558 | - | - | - (aa) | - | - |
ENST00000335987 | OVOL1-201 | 3034 | - | ENSP00000337862 | 267 (aa) | - | O14753 |
ensgID | SNP | Chromosome | Position | SNP-risk | Trait | PubmedID | 95% CI | Or or BEAT | EFO ID |
---|---|---|---|---|---|---|---|---|---|
ENSG00000172818 | rs10896045 | 11 | 65788053 | G | Blood protein levels | 29875488 | [0.12-0.24] unit decrease | 0.18 | EFO_0007937 |
ENSG00000172818 | rs642803 | 11 | 65793149 | T | Urate levels | 23263486 | [0.026-0.045] mg/dl decrease | 0.036 | EFO_0004531 |
ENSG00000172818 | rs642803 | 11 | 65793149 | T | Educational attainment (MTAG) | 30038396 | [0.0049-0.0099] unit increase | 0.0074 | EFO_0004784 |
ENSG00000172818 | rs642803 | 11 | 65793149 | T | Highest math class taken (MTAG) | 30038396 | [0.0058-0.0124] unit increase | 0.0091 | EFO_0004875 |
ENSG00000172818 | rs56019505 | 11 | 65794334 | G | Blond vs. brown/black hair color | 30531825 | NR | 1.087 | EFO_0003924 |
ENSG00000172818 | rs12797706 | 11 | 65793898 | ? | Hair color | 30595370 | EFO_0007822 | ||
ENSG00000172818 | rs10791824 | 11 | 65791795 | ? | Eczema | 30595370 | HP_0000964 | ||
ENSG00000172818 | rs11227302 | 11 | 65787031 | A | Systemic lupus erythematosus | 28714469 | [1.08-1.21] | 1.15 | EFO_0002690 |
ENSG00000172818 | rs644740 | 11 | 65793997 | T | Age of smoking initiation (MTAG) | 30643251 | [0.0059-0.0117] unit increase | 0.00881013 | EFO_0005670 |
ENSG00000172818 | rs644740 | 11 | 65793997 | T | Smoking initiation (ever regular vs never regular) (MTAG) | 30643251 | [0.0051-0.0093] unit decrease | 0.00719881 | EFO_0006527 |
ENSG00000172818 | rs644740 | 11 | 65793997 | T | Smoking initiation (ever regular vs never regular) | 30643251 | [0.0091-0.0191] unit decrease | 0.014078517 | EFO_0006527 |
Ensembl ID | Gene Symbol | Coverage | Identiy | Ortholog | Gene Symbol | Coverage | Identiy | Species |
---|---|---|---|---|---|---|---|---|
ENSG00000172818 | OVOL1 | 100 | 94.634 | ENSCLAG00000016426 | OVOL1 | 79 | 94.068 | Chinchilla_lanigera |
ENSG00000172818 | OVOL1 | 100 | 71.220 | ENSCPBG00000023411 | OVOL1 | 100 | 71.161 | Chrysemys_picta_bellii |
ENSG00000172818 | OVOL1 | 100 | 90.732 | ENSDNOG00000024062 | OVOL1 | 98 | 89.496 | Dasypus_novemcinctus |
ENSG00000172818 | OVOL1 | 100 | 95.131 | ENSDORG00000028510 | Ovol1 | 100 | 95.131 | Dipodomys_ordii |
ENSG00000172818 | OVOL1 | 77 | 97.452 | ENSEEUG00000010161 | OVOL1 | 99 | 96.835 | Erinaceus_europaeus |
ENSG00000172818 | OVOL1 | 80 | 68.902 | ENSGALG00000049996 | OVOL1 | 73 | 67.429 | Gallus_gallus |
ENSG00000172818 | OVOL1 | 100 | 72.195 | ENSGAGG00000008199 | OVOL1 | 100 | 71.536 | Gopherus_agassizii |
ENSG00000172818 | OVOL1 | 100 | 94.757 | ENSJJAG00000024400 | Ovol1 | 100 | 94.757 | Jaculus_jaculus |
ENSG00000172818 | OVOL1 | 100 | 95.506 | MGP_CAROLIEiJ_G0022558 | Ovol1 | 100 | 95.506 | Mus_caroli |
ENSG00000172818 | OVOL1 | 100 | 95.506 | ENSMUSG00000024922 | Ovol1 | 100 | 95.506 | Mus_musculus |
ENSG00000172818 | OVOL1 | 100 | 94.757 | MGP_PahariEiJ_G0014055 | Ovol1 | 100 | 94.757 | Mus_pahari |
ENSG00000172818 | OVOL1 | 100 | 95.880 | MGP_SPRETEiJ_G0023472 | Ovol1 | 100 | 95.880 | Mus_spretus |
ENSG00000172818 | OVOL1 | 100 | 96.255 | ENSOGAG00000016496 | OVOL1 | 100 | 96.255 | Otolemur_garnettii |
ENSG00000172818 | OVOL1 | 95 | 70.769 | ENSPSIG00000002913 | OVOL1 | 100 | 64.748 | Pelodiscus_sinensis |
ENSG00000172818 | OVOL1 | 100 | 94.382 | ENSRNOG00000020669 | Ovol1 | 100 | 94.382 | Rattus_norvegicus |
Go ID | Go_term | PubmedID | Evidence | Category |
---|---|---|---|---|
GO:0000122 | negative regulation of transcription by RNA polymerase II | - | IEA | Process |
GO:0000978 | RNA polymerase II proximal promoter sequence-specific DNA binding | - | IEA | Function |
GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | - | ISA | Function |
GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific | 21873635. | IBA | Function |
GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific | 21873635. | IBA | Function |
GO:0001822 | kidney development | - | IEA | Process |
GO:0005634 | nucleus | 21873635. | IBA | Component |
GO:0007283 | spermatogenesis | - | IEA | Process |
GO:0007498 | mesoderm development | - | IEA | Process |
GO:0009913 | epidermal cell differentiation | 21873635. | IBA | Process |
GO:0043565 | sequence-specific DNA binding | 21873635. | IBA | Function |
GO:0043588 | skin development | - | IEA | Process |
GO:0045892 | negative regulation of transcription, DNA-templated | 21873635. | IBA | Process |
GO:0045944 | positive regulation of transcription by RNA polymerase II | - | IEA | Process |
GO:0046872 | metal ion binding | - | IEA | Function |
GO:0051729 | germline cell cycle switching, mitotic to meiotic cell cycle | - | IEA | Process |
GO:1901994 | negative regulation of meiotic cell cycle phase transition | - | IEA | Process |
GO:2000647 | negative regulation of stem cell proliferation | - | IEA | Process |