EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
27123562	Driver Mutations in Uveal Melanoma: Associations With Gene Expression Profile and Patient Outcomes.	JAMA Ophthalmol	2016 Jul 1	Decatur CL	doi: 10.1001/jamaophthalmol.2016.0903.
27916271	Correlation of Gene Mutation Status with Copy Number Profile in Uveal Melanoma.	Ophthalmology	2017 Apr	Yavuzyigitoglu S	doi: 10.1016/j.ophtha.2016.10.039
29476293	Whole-exome sequencing of a meningeal melanocytic tumour reveals activating CYSLTR2 and EIF1AX hotspot mutations and similarities to uveal melanoma.	Brain Tumor Pathol	2018 Apr	K??sters-Vandevelde HVN	doi: 10.1007/s10014-018-0308-1
26911375	Prevalence and phenotypic correlations of EIF1AX mutations in thyroid nodules.	Endocr Relat Cancer	2016 Apr	Karunamurthy A	doi: 10.1530/ERC-16-0043
28646021	EIF1AX and NRAS Mutations Co-occur and Cooperate in Low-Grade Serous Ovarian Carcinomas.	Cancer Res	2017 Aug 15	Etemadmoghadam D	doi: 10.1158/0008-5472.CAN-16-2224

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BRCA	chrX	20132224	Missense_Mutation	NA	E99K	0.14
BRCA	chrX	20130596	Nonsense_Mutation	NA	E117*	0.22
BRCA	chrX	20138614	Missense_Mutation	NA	G9R	0.11	eIF-1a
CESC	chrX	20141632	Missense_Mutation	novel	K3N	0.29
CESC	chrX	20125957	3'UTR	novel		0.47
CESC	chrX	20138616	Missense_Mutation	NA	G8E	0.28	eIF-1a
CHOL	chrX	20141647	5'UTR	novel		0.36
COAD	chrX	20141763	5'UTR	novel		0.38
COAD	chrX	20134002	Missense_Mutation	NA	W70C	0.51
COAD	chrX	20141807	5'UTR	novel		0.42
ESCA	chrX	20141648	5'UTR	novel		0.63
ESCA	chrX	20125809	3'UTR	novel		0.13
ESCA	chrX	20127667	3'UTR	novel		0.63
GBM	chrX	20136329	Intron	novel		0.15
GBM	chrX	20130516	Splice_Region	rs768926880	D143D	0.36
HNSC	chrX	20138613	Missense_Mutation	NA	G9D	0.8	eIF-1a
KIRP	chrX	20134003	Missense_Mutation	NA	W70L	0.6
LGG	chrX	20138595	Missense_Mutation	NA	G15V	0.85	eIF-1a
LGG	chrX	20138595	Missense_Mutation	NA	G15D	0.73	eIF-1a
LGG	chrX	20132204	Silent	novel	A105A	0.32
LGG	chrX	20138611	Missense_Mutation	rs757280897	K10E	0.91	eIF-1a
LIHC	chrX	20128268	3'UTR	novel		0.13
LIHC	chrX	20136066	Intron	novel		0.85
LUAD	chrX	20128219	3'UTR	novel		0.25
LUAD	chrX	20138599	Missense_Mutation	NA	R14W	0.14	eIF-1a
LUAD	chrX	20130598	Missense_Mutation	NA	N116S	0.79
LUSC	chrX	20130566	Missense_Mutation	novel	D127N	0.27
OV	chrX	20138624	Splice_Site	NA	X6_splice	0.69
OV	chrX	20138616	Missense_Mutation	NA	G8V	0.46	eIF-1a
SARC	chrX	20141756	5'UTR	novel		0.86
SARC	chrX	20138594	Silent	novel	G15G	0.32
SKCM	chrX	20138605	Missense_Mutation	NA	R12G	0.9	eIF-1a
SKCM	chrX	20138619	Missense_Mutation	NA	K7R	0.73	eIF-1a
SKCM	chrX	20138611	Missense_Mutation	rs757280897	K10E	0.29	eIF-1a
STAD	chrX	20135781	Missense_Mutation	NA	G54D	0.15	eIF-1a
STAD	chrX	20135836	Missense_Mutation	NA	A36T	0.24	eIF-1a
STAD	chrX	20135786	Silent	rs151115944	F52F	0.47
THCA	chrX	20138617	Missense_Mutation	NA	G8R	0.31	eIF-1a
THCA	chrX	20130608	Splice_Site	NA	X113_splice	0.18
THCA	chrX	20138613	Missense_Mutation	NA	G9D	0.21	eIF-1a
THCA	chrX	20138613	Missense_Mutation	NA	G9D	0.6	eIF-1a
THCA	chrX	20138576	In_Frame_Ins	novel	R14_S21dup	0.19	eIF-1a
THCA	chrX	20130574	Missense_Mutation	novel	G124V	0.31
THCA	chrX	20130575	Nonsense_Mutation	novel	G124*	0.31
THCA	chrX	20138614	Missense_Mutation	NA	G9R	0.8	eIF-1a
THCA	chrX	20130607	Missense_Mutation	novel	A113V	0.35
THYM	chrX	20141625	Missense_Mutation	novel	G6S	0.08	eIF-1a
THYM	chrX	20141630	Missense_Mutation	novel	N4S	0.15
UCEC	chrX	20133991	Missense_Mutation	NA	S74L	0.3
UCEC	chrX	20138602	Missense_Mutation	NA	R13C	0.2	eIF-1a
UCEC	chrX	20133990	Silent	novel	S74S	0.37
UCEC	chrX	20125915	3'UTR	novel		0.32
UCEC	chrX	20134002	Missense_Mutation	NA	W70C	0.11
UCEC	chrX	20134003	Missense_Mutation	novel	W70S	0.37
UCEC	chrX	20132201	Silent	rs148556006	Y106Y	0.34
UCEC	chrX	20134002	Missense_Mutation	NA	W70C	0.16
UCEC	chrX	20141649	5'UTR	novel		0.37
UCEC	chrX	20127261	3'UTR	novel		0.32
UCEC	chrX	20125967	3'UTR	novel		0.44
UCEC	chrX	20132200	Missense_Mutation	novel	G107S	0.43
UCEC	chrX	20127434	3'UTR	novel		0.38
UCEC	chrX	20125779	3'UTR	novel		0.33
UCEC	chrX	20141735	5'UTR	novel		0.17
UCEC	chrX	20138601	Missense_Mutation	NA	R13H	0.46	eIF-1a
UCEC	chrX	20125662	3'UTR	novel		0.67
UCEC	chrX	20125954	3'UTR	novel		0.2
UCEC	chrX	20133990	Silent	novel	S74S	0.36
UCEC	chrX	20135822	Silent	novel	K40K	0.28
UCEC	chrX	20127256	3'UTR	novel		0.39
UCEC	chrX	20138602	Missense_Mutation	NA	R13C	0.27	eIF-1a
UCEC	chrX	20125951	3'UTR	novel		0.4
UCEC	chrX	20127442	3'UTR	novel		0.47
UCEC	chrX	20128292	3'UTR	novel		0.51
UCEC	chrX	20128249	3'UTR	novel		0.17
UCEC	chrX	20138601	Missense_Mutation	NA	R13H	0.31	eIF-1a
UCEC	chrX	20138601	Missense_Mutation	NA	R13H	0.27	eIF-1a
UCEC	chrX	20132225	Silent	rs142945049	D98D	0.25
UCEC	chrX	20141637	Missense_Mutation	NA	P2S	0.29
UCEC	chrX	20127499	3'UTR	novel		0.36
UCEC	chrX	20127628	3'UTR	novel		0.35
UCEC	chrX	20132224	Missense_Mutation	NA	E99K	0.41
UCS	chrX	20136311	Intron	novel		0.44
UVM	chrX	20138622	Missense_Mutation	NA	G6D	0.93	eIF-1a
UVM	chrX	20138595	Missense_Mutation	NA	G15D	1	eIF-1a
UVM	chrX	20138617	Missense_Mutation	novel	G8R	0.47	eIF-1a
UVM	chrX	20138614	Missense_Mutation	NA	G9R	0.87	eIF-1a
UVM	chrX	20138622	Missense_Mutation	NA	G6D	0.93	eIF-1a
UVM	chrX	20138617	In_Frame_Del	novel	K7_G8delinsR	1	eIF-1a
UVM	chrX	20134004	Missense_Mutation	novel	W70R	0.93
UVM	chrX	20138613	Missense_Mutation	NA	G9D	0.49	eIF-1a
UVM	chrX	20138617	Missense_Mutation	NA	G8R	0.42	eIF-1a
UVM	chrX	20138595	Missense_Mutation	NA	G15D	0.23	eIF-1a

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
READ	AMP	0.1091	0.13718
SARC	AMP	0.2879	0.19108
THCA	DEL	0.002	0.21991

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0029	Kaplan-Meier Survival Analysis
STAD	0.043	Kaplan-Meier Survival Analysis
SARC	0.044	Kaplan-Meier Survival Analysis
MESO	0.03	Kaplan-Meier Survival Analysis
HNSC	0.0014	Kaplan-Meier Survival Analysis
SKCM	0.0023	Kaplan-Meier Survival Analysis
PRAD	0.042	Kaplan-Meier Survival Analysis
LUSC	0.0097	Kaplan-Meier Survival Analysis
ESCA	0.022	Kaplan-Meier Survival Analysis
KIRP	0.003	Kaplan-Meier Survival Analysis
COAD	0.021	Kaplan-Meier Survival Analysis
LIHC	0.0099	Kaplan-Meier Survival Analysis
LGG	0.0035	Kaplan-Meier Survival Analysis
OV	0.00075	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000173674 (Gene tree)
Gene ID: 1964
Gene Symbol: EIF1AX
Alias: eIF-1A|eIF-4C|EIF4C|EIF1A
Full Name: eukaryotic translation initiation factor 1A X-linked
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 17,331 bases
Position: chrX:20,124,518-20,141,848
Accession: 3250
RBP type: canonical RBP
Summary: This gene encodes an essential eukaryotic translation initiation factor. The protein is required for the binding of the 43S complex (a 40S subunit, eIF2/GTP/Met-tRNAi and eIF3) to the 5' end of capped RNA. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000368927	eIF-1a	PF01176.19	8.3e-21	1	1
ENSP00000368912	eIF-1a	PF01176.19	1.5e-20	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
7890705	Protein synthesis initiation factor eIF-1A is a moderately abundant RNA-binding protein.	J Biol Chem	1995 Mar 17	Wei CL	-
10678173	The eIF1A solution structure reveals a large RNA-binding surface important for scanning function.	Mol Cell	2000 Jan	Battiste JL	-
16971461	Zfp206 regulates ES cell gene expression and differentiation.	Nucleic Acids Res	2006	Zhang W	-
17673174	Translation initiation factor eIF1A possesses RNA annealing activity in its oligonucleotide-binding fold.	Biochem Biophys Res Commun	2007 Sep 28	Kwon SH	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000379607	EIF1AX-202	4427	-	ENSP00000368927	144 (aa)	-	P47813
ENST00000379593	EIF1AX-201	765	-	ENSP00000368912	116 (aa)	-	X6RAC9

Gene Model

Click here to download ENSG00000173674's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03013	RNA transport	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000173674's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000173674	EIF1AX	100	99.306	ENSG00000198692	EIF1AY	100	99.306

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000173674	EIF1AX	100	86.806	ENSAPOG00000017330	eif1axb	94	86.806	Acanthochromis_polyacanthus
ENSG00000173674	EIF1AX	100	99.306	ENSAPOG00000005336	eif1axb	100	99.306	Acanthochromis_polyacanthus
ENSG00000173674	EIF1AX	99	97.887	ENSAMEG00000016604	EIF1AX	100	97.887	Ailuropoda_melanoleuca
ENSG00000173674	EIF1AX	100	86.806	ENSACIG00000009147	eif1axb	88	86.806	Amphilophus_citrinellus
ENSG00000173674	EIF1AX	100	99.306	ENSAOCG00000018986	eif1axb	100	99.306	Amphiprion_ocellaris
ENSG00000173674	EIF1AX	100	99.306	ENSAPEG00000005361	eif1axb	100	99.306	Amphiprion_percula
ENSG00000173674	EIF1AX	100	98.611	ENSATEG00000021109	eif1axb	90	98.611	Anabas_testudineus
ENSG00000173674	EIF1AX	100	99.306	ENSACAG00000012660	-	100	99.306	Anolis_carolinensis
ENSG00000173674	EIF1AX	100	100.000	ENSANAG00000030856	EIF1AX	100	100.000	Aotus_nancymaae
ENSG00000173674	EIF1AX	89	91.262	ENSANAG00000029127	-	88	91.262	Aotus_nancymaae
ENSG00000173674	EIF1AX	99	97.391	ENSANAG00000036820	-	97	97.391	Aotus_nancymaae
ENSG00000173674	EIF1AX	96	78.986	ENSANAG00000029064	-	90	79.200	Aotus_nancymaae
ENSG00000173674	EIF1AX	100	98.611	ENSACLG00000015402	eif1axb	100	98.611	Astatotilapia_calliptera
ENSG00000173674	EIF1AX	100	98.611	ENSAMXG00000032495	eif1axb	100	98.611	Astyanax_mexicanus
ENSG00000173674	EIF1AX	100	97.917	ENSAMXG00000031325	eif1axa	100	97.917	Astyanax_mexicanus
ENSG00000173674	EIF1AX	100	100.000	ENSBTAG00000017633	EIF1AX	100	100.000	Bos_taurus
ENSG00000173674	EIF1AX	97	69.286	WBGene00019162	eif-1.A	59	70.992	Caenorhabditis_elegans
ENSG00000173674	EIF1AX	100	100.000	ENSCJAG00000005371	EIF1AX	100	100.000	Callithrix_jacchus
ENSG00000173674	EIF1AX	100	100.000	ENSCAFG00000032071	EIF1AX	100	100.000	Canis_familiaris
ENSG00000173674	EIF1AX	100	100.000	ENSCAFG00020004588	EIF1AX	100	100.000	Canis_lupus_dingo
ENSG00000173674	EIF1AX	98	66.087	ENSCHIG00000000406	-	89	70.192	Capra_hircus
ENSG00000173674	EIF1AX	100	100.000	ENSCHIG00000021471	EIF1AX	100	100.000	Capra_hircus
ENSG00000173674	EIF1AX	100	100.000	ENSTSYG00000012460	EIF1AX	100	100.000	Carlito_syrichta
ENSG00000173674	EIF1AX	90	82.171	ENSCAPG00000006145	-	99	83.200	Cavia_aperea
ENSG00000173674	EIF1AX	91	96.183	ENSCAPG00000006533	-	91	96.183	Cavia_aperea
ENSG00000173674	EIF1AX	91	87.786	ENSCAPG00000002546	-	91	87.786	Cavia_aperea
ENSG00000173674	EIF1AX	100	98.611	ENSCAPG00000005844	-	100	98.611	Cavia_aperea
ENSG00000173674	EIF1AX	100	100.000	ENSCPOG00000039205	-	100	100.000	Cavia_porcellus
ENSG00000173674	EIF1AX	100	100.000	ENSCCAG00000020517	-	100	100.000	Cebus_capucinus
ENSG00000173674	EIF1AX	100	99.306	ENSCCAG00000020815	EIF1AY	100	99.306	Cebus_capucinus
ENSG00000173674	EIF1AX	91	92.366	ENSCCAG00000026888	-	93	92.366	Cebus_capucinus
ENSG00000173674	EIF1AX	100	100.000	ENSCATG00000033237	EIF1AX	100	100.000	Cercocebus_atys
ENSG00000173674	EIF1AX	100	87.500	ENSCATG00000029207	-	100	87.500	Cercocebus_atys
ENSG00000173674	EIF1AX	100	100.000	ENSCLAG00000000709	EIF1AX	100	100.000	Chinchilla_lanigera
ENSG00000173674	EIF1AX	100	100.000	ENSCSAG00000014562	EIF1AX	100	100.000	Chlorocebus_sabaeus
ENSG00000173674	EIF1AX	100	99.306	ENSCSAG00000018313	EIF1AY	100	99.306	Chlorocebus_sabaeus
ENSG00000173674	EIF1AX	100	98.611	ENSCHOG00000008111	EIF1AX	100	98.611	Choloepus_hoffmanni
ENSG00000173674	EIF1AX	100	99.306	ENSCPBG00000006126	EIF1AY	100	99.306	Chrysemys_picta_bellii
ENSG00000173674	EIF1AX	94	80.147	ENSCING00000006224	-	70	80.916	Ciona_intestinalis
ENSG00000173674	EIF1AX	83	76.042	ENSCSAVG00000004949	-	62	76.923	Ciona_savignyi
ENSG00000173674	EIF1AX	100	100.000	ENSCANG00000013429	EIF1AX	100	100.000	Colobus_angolensis_palliatus
ENSG00000173674	EIF1AX	100	98.611	ENSCGRG00001005357	Eif1a	100	98.611	Cricetulus_griseus_chok1gshd
ENSG00000173674	EIF1AX	100	100.000	ENSCGRG00001022852	-	100	100.000	Cricetulus_griseus_chok1gshd
ENSG00000173674	EIF1AX	85	74.747	ENSCGRG00001012123	-	84	77.064	Cricetulus_griseus_chok1gshd
ENSG00000173674	EIF1AX	100	96.528	ENSCGRG00000015188	-	86	96.528	Cricetulus_griseus_crigri
ENSG00000173674	EIF1AX	100	98.611	ENSCGRG00000018882	Eif1a	100	98.611	Cricetulus_griseus_crigri
ENSG00000173674	EIF1AX	85	74.747	ENSCGRG00000000728	-	84	77.064	Cricetulus_griseus_crigri
ENSG00000173674	EIF1AX	91	90.076	ENSCSEG00000015312	eif1axb	90	90.076	Cynoglossus_semilaevis
ENSG00000173674	EIF1AX	100	98.611	ENSCVAG00000016422	eif1axb	100	98.611	Cyprinodon_variegatus
ENSG00000173674	EIF1AX	100	96.528	ENSDARG00000029003	eif1axa	100	96.528	Danio_rerio
ENSG00000173674	EIF1AX	100	99.306	ENSDARG00000057912	eif1axb	100	99.306	Danio_rerio
ENSG00000173674	EIF1AX	100	100.000	ENSDNOG00000045675	EIF1AX	100	100.000	Dasypus_novemcinctus
ENSG00000173674	EIF1AX	100	99.306	ENSDORG00000030047	-	100	99.306	Dipodomys_ordii
ENSG00000173674	EIF1AX	97	99.107	ENSDORG00000011536	-	100	100.000	Dipodomys_ordii
ENSG00000173674	EIF1AX	100	77.241	FBgn0026250	eIF1A	89	82.576	Drosophila_melanogaster
ENSG00000173674	EIF1AX	59	100.000	ENSETEG00000009320	-	100	100.000	Echinops_telfairi
ENSG00000173674	EIF1AX	90	97.692	ENSETEG00000001849	-	92	97.692	Echinops_telfairi
ENSG00000173674	EIF1AX	99	89.510	ENSETEG00000020091	-	91	90.000	Echinops_telfairi
ENSG00000173674	EIF1AX	91	92.366	ENSEBUG00000008167	EIF1AY	91	92.366	Eptatretus_burgeri
ENSG00000173674	EIF1AX	100	100.000	ENSEASG00005014703	EIF1AX	100	100.000	Equus_asinus_asinus
ENSG00000173674	EIF1AX	100	98.276	ENSEASG00005009834	EIF1AY	97	98.276	Equus_asinus_asinus
ENSG00000173674	EIF1AX	100	99.306	ENSECAG00000006469	EIF1AX	100	99.306	Equus_caballus
ENSG00000173674	EIF1AX	91	78.626	ENSEEUG00000007518	EIF1AX	92	78.626	Erinaceus_europaeus
ENSG00000173674	EIF1AX	100	97.917	ENSELUG00000012432	eif1ax	78	96.460	Esox_lucius
ENSG00000173674	EIF1AX	100	97.917	ENSELUG00000021070	IF1AX	100	97.917	Esox_lucius
ENSG00000173674	EIF1AX	100	100.000	ENSFCAG00000035249	EIF1AX	100	100.000	Felis_catus
ENSG00000173674	EIF1AX	90	98.077	ENSFALG00000004207	EIF1AY	100	98.077	Ficedula_albicollis
ENSG00000173674	EIF1AX	100	100.000	ENSFDAG00000011608	-	100	100.000	Fukomys_damarensis
ENSG00000173674	EIF1AX	100	77.083	ENSFDAG00000010943	-	80	76.336	Fukomys_damarensis
ENSG00000173674	EIF1AX	100	99.306	ENSFHEG00000006145	eif1axb	100	99.306	Fundulus_heteroclitus
ENSG00000173674	EIF1AX	99	100.000	ENSGMOG00000004469	eif1axb	100	100.000	Gadus_morhua
ENSG00000173674	EIF1AX	100	99.306	ENSGALG00000016410	EIF1AY	100	99.306	Gallus_gallus
ENSG00000173674	EIF1AX	100	99.306	ENSGAFG00000004972	eif1axb	100	99.306	Gambusia_affinis
ENSG00000173674	EIF1AX	100	99.306	ENSGACG00000012829	eif1axb	100	99.306	Gasterosteus_aculeatus
ENSG00000173674	EIF1AX	100	99.306	ENSGAGG00000023700	EIF1AY	100	99.306	Gopherus_agassizii
ENSG00000173674	EIF1AX	91	91.603	ENSGGOG00000043430	-	91	91.603	Gorilla_gorilla
ENSG00000173674	EIF1AX	91	91.603	ENSGGOG00000037004	-	91	91.603	Gorilla_gorilla
ENSG00000173674	EIF1AX	100	100.000	ENSGGOG00000012186	-	100	100.000	Gorilla_gorilla
ENSG00000173674	EIF1AX	100	98.611	ENSHBUG00000011962	eif1axb	100	98.611	Haplochromis_burtoni
ENSG00000173674	EIF1AX	100	100.000	ENSHGLG00000001280	EIF1AX	100	100.000	Heterocephalus_glaber_female
ENSG00000173674	EIF1AX	100	100.000	ENSHGLG00100020787	-	100	100.000	Heterocephalus_glaber_male
ENSG00000173674	EIF1AX	100	96.528	ENSHGLG00100001863	-	100	100.000	Heterocephalus_glaber_male
ENSG00000173674	EIF1AX	97	98.214	ENSHGLG00100008297	-	86	97.561	Heterocephalus_glaber_male
ENSG00000173674	EIF1AX	97	95.536	ENSHGLG00100018032	-	100	94.964	Heterocephalus_glaber_male
ENSG00000173674	EIF1AX	100	98.611	ENSHCOG00000007746	eif1axb	82	98.611	Hippocampus_comes
ENSG00000173674	EIF1AX	100	98.611	ENSIPUG00000013916	-	100	98.611	Ictalurus_punctatus
ENSG00000173674	EIF1AX	100	99.306	ENSIPUG00000021259	EIF1AX	100	99.306	Ictalurus_punctatus
ENSG00000173674	EIF1AX	100	100.000	ENSSTOG00000026117	EIF1AX	100	100.000	Ictidomys_tridecemlineatus
ENSG00000173674	EIF1AX	99	92.174	ENSJJAG00000021591	-	96	92.174	Jaculus_jaculus
ENSG00000173674	EIF1AX	100	97.222	ENSJJAG00000011849	-	100	97.222	Jaculus_jaculus
ENSG00000173674	EIF1AX	78	87.611	ENSJJAG00000021929	-	95	82.677	Jaculus_jaculus
ENSG00000173674	EIF1AX	100	97.222	ENSJJAG00000014189	-	100	97.222	Jaculus_jaculus
ENSG00000173674	EIF1AX	100	99.306	ENSJJAG00000016949	-	100	99.306	Jaculus_jaculus
ENSG00000173674	EIF1AX	100	98.611	ENSKMAG00000011900	eif1axb	85	98.611	Kryptolebias_marmoratus
ENSG00000173674	EIF1AX	100	99.306	ENSLBEG00000017217	eif1axb	100	99.306	Labrus_bergylta
ENSG00000173674	EIF1AX	100	98.611	ENSLOCG00000003622	eif1axb	95	98.611	Lepisosteus_oculatus
ENSG00000173674	EIF1AX	100	97.241	ENSLAFG00000007016	EIF1AX	100	97.241	Loxodonta_africana
ENSG00000173674	EIF1AX	100	100.000	ENSMFAG00000000439	-	100	100.000	Macaca_fascicularis
ENSG00000173674	EIF1AX	100	99.306	ENSMMUG00000043715	EIF1AY	100	99.306	Macaca_mulatta
ENSG00000173674	EIF1AX	100	100.000	ENSMMUG00000000193	EIF1AX	100	100.000	Macaca_mulatta
ENSG00000173674	EIF1AX	100	100.000	ENSMNEG00000035197	EIF1AX	100	100.000	Macaca_nemestrina
ENSG00000173674	EIF1AX	100	85.417	ENSMLEG00000043398	-	100	85.417	Mandrillus_leucophaeus
ENSG00000173674	EIF1AX	100	100.000	ENSMLEG00000031392	EIF1AX	100	100.000	Mandrillus_leucophaeus
ENSG00000173674	EIF1AX	100	99.306	ENSMAMG00000008210	eif1axb	100	99.306	Mastacembelus_armatus
ENSG00000173674	EIF1AX	100	98.611	ENSMZEG00005020621	eif1axb	100	98.611	Maylandia_zebra
ENSG00000173674	EIF1AX	97	99.281	ENSMGAG00000014664	EIF1AY	100	99.281	Meleagris_gallopavo
ENSG00000173674	EIF1AX	100	98.611	ENSMAUG00000019719	-	100	98.611	Mesocricetus_auratus
ENSG00000173674	EIF1AX	100	100.000	ENSMAUG00000012396	-	100	100.000	Mesocricetus_auratus
ENSG00000173674	EIF1AX	100	100.000	ENSMICG00000004110	EIF1AX	100	100.000	Microcebus_murinus
ENSG00000173674	EIF1AX	100	100.000	ENSMOCG00000013551	-	100	100.000	Microtus_ochrogaster
ENSG00000173674	EIF1AX	100	97.917	ENSMMOG00000013111	eif1axb	80	97.917	Mola_mola
ENSG00000173674	EIF1AX	100	100.000	ENSMODG00000027820	-	100	100.000	Monodelphis_domestica
ENSG00000173674	EIF1AX	91	92.366	ENSMODG00000024822	-	91	92.366	Monodelphis_domestica
ENSG00000173674	EIF1AX	100	99.306	ENSMALG00000017651	eif1axb	100	99.306	Monopterus_albus
ENSG00000173674	EIF1AX	100	100.000	MGP_CAROLIEiJ_G0033531	-	100	100.000	Mus_caroli
ENSG00000173674	EIF1AX	100	98.611	MGP_CAROLIEiJ_G0022256	Eif1a	100	98.611	Mus_caroli
ENSG00000173674	EIF1AX	91	92.366	ENSMUSG00000072905	Gm2016	91	92.366	Mus_musculus
ENSG00000173674	EIF1AX	91	90.840	ENSMUSG00000096049	Gm2075	91	90.840	Mus_musculus
ENSG00000173674	EIF1AX	91	93.893	ENSMUSG00000079034	Gm8300	91	93.893	Mus_musculus
ENSG00000173674	EIF1AX	91	90.840	ENSMUSG00000096803	Gm6803	91	90.840	Mus_musculus
ENSG00000173674	EIF1AX	91	90.076	ENSMUSG00000092019	Gm4027	91	90.076	Mus_musculus
ENSG00000173674	EIF1AX	100	91.667	ENSMUSG00000113201	Gm21936	91	92.366	Mus_musculus
ENSG00000173674	EIF1AX	91	93.130	ENSMUSG00000095717	Gm2056	91	93.130	Mus_musculus
ENSG00000173674	EIF1AX	91	92.366	ENSMUSG00000114075	Gm16368	91	92.366	Mus_musculus
ENSG00000173674	EIF1AX	91	93.130	ENSMUSG00000095724	Gm21319	91	93.130	Mus_musculus
ENSG00000173674	EIF1AX	91	93.893	ENSMUSG00000095799	Gm8332	91	93.893	Mus_musculus
ENSG00000173674	EIF1AX	91	93.130	ENSMUSG00000096619	Gm2035	91	93.130	Mus_musculus
ENSG00000173674	EIF1AX	100	98.611	ENSMUSG00000057561	Eif1a	100	98.611	Mus_musculus
ENSG00000173674	EIF1AX	91	93.893	ENSMUSG00000113805	Gm5788	91	93.893	Mus_musculus
ENSG00000173674	EIF1AX	91	92.366	ENSMUSG00000079029	Gm5662	91	92.366	Mus_musculus
ENSG00000173674	EIF1AX	100	100.000	ENSMUSG00000067194	Eif1ax	100	100.000	Mus_musculus
ENSG00000173674	EIF1AX	91	93.130	ENSMUSG00000113971	Gm2022	91	93.130	Mus_musculus
ENSG00000173674	EIF1AX	91	90.076	ENSMUSG00000079031	BB287469	91	90.076	Mus_musculus
ENSG00000173674	EIF1AX	91	93.893	ENSMUSG00000093847	Gm5039	91	93.893	Mus_musculus
ENSG00000173674	EIF1AX	99	100.000	MGP_PahariEiJ_G0032070	-	100	100.000	Mus_pahari
ENSG00000173674	EIF1AX	71	96.341	MGP_PahariEiJ_G0015759	-	86	96.341	Mus_pahari
ENSG00000173674	EIF1AX	85	97.541	MGP_SPRETEiJ_G0023167	-	98	97.541	Mus_spretus
ENSG00000173674	EIF1AX	91	92.366	MGP_SPRETEiJ_G0014754	-	91	92.366	Mus_spretus
ENSG00000173674	EIF1AX	100	100.000	MGP_SPRETEiJ_G0034701	-	100	100.000	Mus_spretus
ENSG00000173674	EIF1AX	97	99.281	ENSMPUG00000003337	EIF1AX	98	99.281	Mustela_putorius_furo
ENSG00000173674	EIF1AX	100	100.000	ENSMLUG00000029101	-	100	100.000	Myotis_lucifugus
ENSG00000173674	EIF1AX	94	96.296	ENSMLUG00000022390	-	100	96.296	Myotis_lucifugus
ENSG00000173674	EIF1AX	100	99.306	ENSMLUG00000012977	-	100	99.306	Myotis_lucifugus
ENSG00000173674	EIF1AX	88	85.714	ENSNGAG00000014156	-	88	85.714	Nannospalax_galili
ENSG00000173674	EIF1AX	100	100.000	ENSNGAG00000018551	-	100	100.000	Nannospalax_galili
ENSG00000173674	EIF1AX	100	77.083	ENSNGAG00000015087	-	100	77.083	Nannospalax_galili
ENSG00000173674	EIF1AX	100	98.611	ENSNGAG00000016970	Eif1a	100	98.611	Nannospalax_galili
ENSG00000173674	EIF1AX	100	98.611	ENSNBRG00000008321	eif1axb	100	98.611	Neolamprologus_brichardi
ENSG00000173674	EIF1AX	100	100.000	ENSNLEG00000009913	-	100	100.000	Nomascus_leucogenys
ENSG00000173674	EIF1AX	95	67.153	ENSMEUG00000010732	-	100	67.153	Notamacropus_eugenii
ENSG00000173674	EIF1AX	94	65.926	ENSODEG00000017860	-	88	66.412	Octodon_degus
ENSG00000173674	EIF1AX	100	100.000	ENSODEG00000017687	-	100	100.000	Octodon_degus
ENSG00000173674	EIF1AX	91	88.889	ENSODEG00000020083	-	91	88.889	Octodon_degus
ENSG00000173674	EIF1AX	100	97.917	ENSONIG00000008209	eif1axb	100	97.917	Oreochromis_niloticus
ENSG00000173674	EIF1AX	97	98.571	ENSOANG00000013689	EIF1AX	100	98.571	Ornithorhynchus_anatinus
ENSG00000173674	EIF1AX	100	97.917	ENSOCUG00000010188	-	100	97.917	Oryctolagus_cuniculus
ENSG00000173674	EIF1AX	97	99.281	ENSOCUG00000013646	-	100	99.281	Oryctolagus_cuniculus
ENSG00000173674	EIF1AX	100	97.222	ENSORLG00000002444	eif1axb	100	97.222	Oryzias_latipes
ENSG00000173674	EIF1AX	100	97.222	ENSORLG00020013074	eif1axb	100	97.222	Oryzias_latipes_hni
ENSG00000173674	EIF1AX	100	97.222	ENSORLG00015010034	eif1axb	100	97.222	Oryzias_latipes_hsok
ENSG00000173674	EIF1AX	84	78.512	ENSOMEG00000018980	-	78	78.512	Oryzias_melastigma
ENSG00000173674	EIF1AX	91	84.733	ENSOGAG00000028712	-	90	84.733	Otolemur_garnettii
ENSG00000173674	EIF1AX	90	96.923	ENSOGAG00000024358	-	90	96.923	Otolemur_garnettii
ENSG00000173674	EIF1AX	97	99.281	ENSOGAG00000008182	-	97	99.281	Otolemur_garnettii
ENSG00000173674	EIF1AX	99	79.021	ENSOGAG00000033839	-	90	79.070	Otolemur_garnettii
ENSG00000173674	EIF1AX	100	100.000	ENSOARG00000015373	EIF1AX	100	100.000	Ovis_aries
ENSG00000173674	EIF1AX	100	100.000	ENSPPAG00000033962	EIF1AX	100	100.000	Pan_paniscus
ENSG00000173674	EIF1AX	100	100.000	ENSPPRG00000008180	-	100	100.000	Panthera_pardus
ENSG00000173674	EIF1AX	100	100.000	ENSPTIG00000012582	-	100	100.000	Panthera_tigris_altaica
ENSG00000173674	EIF1AX	100	100.000	ENSPTIG00000002401	-	100	100.000	Panthera_tigris_altaica
ENSG00000173674	EIF1AX	100	98.611	ENSPTRG00000022504	EIF1AY	100	98.611	Pan_troglodytes
ENSG00000173674	EIF1AX	88	88.889	ENSPTRG00000021728	-	98	88.889	Pan_troglodytes
ENSG00000173674	EIF1AX	100	100.000	ENSPANG00000030224	-	100	100.000	Papio_anubis
ENSG00000173674	EIF1AX	100	93.056	ENSPANG00000035342	-	100	93.056	Papio_anubis
ENSG00000173674	EIF1AX	100	98.611	ENSPKIG00000012288	eif1axa	81	98.611	Paramormyrops_kingsleyae
ENSG00000173674	EIF1AX	100	100.000	ENSPKIG00000019062	EIF1AX	100	100.000	Paramormyrops_kingsleyae
ENSG00000173674	EIF1AX	98	98.582	ENSPSIG00000004858	EIF1AY	99	98.582	Pelodiscus_sinensis
ENSG00000173674	EIF1AX	80	95.652	ENSPMGG00000008528	eif1axb	86	95.652	Periophthalmus_magnuspinnatus
ENSG00000173674	EIF1AX	100	100.000	ENSPCIG00000007615	EIF1AX	100	100.000	Phascolarctos_cinereus
ENSG00000173674	EIF1AX	100	99.306	ENSPFOG00000002363	eif1axb	100	99.306	Poecilia_formosa
ENSG00000173674	EIF1AX	100	99.306	ENSPLAG00000011773	eif1axb	100	99.306	Poecilia_latipinna
ENSG00000173674	EIF1AX	100	99.306	ENSPMEG00000005293	eif1axb	100	99.306	Poecilia_mexicana
ENSG00000173674	EIF1AX	100	98.611	ENSPREG00000011381	eif1axb	95	98.611	Poecilia_reticulata
ENSG00000173674	EIF1AX	100	100.000	ENSPPYG00000020176	EIF1AX	100	100.000	Pongo_abelii
ENSG00000173674	EIF1AX	87	77.600	ENSPCAG00000009150	EIF1AX	91	77.600	Procavia_capensis
ENSG00000173674	EIF1AX	100	100.000	ENSPCOG00000020014	-	100	100.000	Propithecus_coquereli
ENSG00000173674	EIF1AX	100	97.222	ENSPVAG00000003521	EIF1AX	100	97.222	Pteropus_vampyrus
ENSG00000173674	EIF1AX	100	98.611	ENSPNYG00000024270	eif1axb	100	98.611	Pundamilia_nyererei
ENSG00000173674	EIF1AX	93	96.296	ENSPNAG00000010444	-	79	96.296	Pygocentrus_nattereri
ENSG00000173674	EIF1AX	100	97.917	ENSPNAG00000021235	eif1axb	100	97.917	Pygocentrus_nattereri
ENSG00000173674	EIF1AX	100	100.000	ENSRNOG00000005736	Eif1ax	100	100.000	Rattus_norvegicus
ENSG00000173674	EIF1AX	100	98.611	ENSRNOG00000031421	Eif1a	100	98.611	Rattus_norvegicus
ENSG00000173674	EIF1AX	65	98.925	ENSRBIG00000035786	-	99	98.925	Rhinopithecus_bieti
ENSG00000173674	EIF1AX	99	100.000	ENSRBIG00000028406	-	100	100.000	Rhinopithecus_bieti
ENSG00000173674	EIF1AX	100	100.000	ENSRROG00000042555	EIF1AX	100	100.000	Rhinopithecus_roxellana
ENSG00000173674	EIF1AX	100	99.306	ENSRROG00000016917	EIF1AY	100	99.306	Rhinopithecus_roxellana
ENSG00000173674	EIF1AX	86	67.000	YMR260C	-	86	65.649	Saccharomyces_cerevisiae
ENSG00000173674	EIF1AX	100	77.931	ENSSBOG00000029580	-	91	77.273	Saimiri_boliviensis_boliviensis
ENSG00000173674	EIF1AX	100	100.000	ENSSBOG00000031558	EIF1AX	100	100.000	Saimiri_boliviensis_boliviensis
ENSG00000173674	EIF1AX	97	100.000	ENSSHAG00000010995	EIF1AX	99	100.000	Sarcophilus_harrisii
ENSG00000173674	EIF1AX	100	100.000	ENSSFOG00015013214	EIF1AX	100	100.000	Scleropages_formosus
ENSG00000173674	EIF1AX	100	99.306	ENSSFOG00015017238	eif1ax	100	99.306	Scleropages_formosus
ENSG00000173674	EIF1AX	100	97.222	ENSSMAG00000009834	eif1axb	100	97.222	Scophthalmus_maximus
ENSG00000173674	EIF1AX	100	99.306	ENSSDUG00000004342	eif1axb	100	99.306	Seriola_dumerili
ENSG00000173674	EIF1AX	100	99.306	ENSSLDG00000008477	eif1axb	100	99.306	Seriola_lalandi_dorsalis
ENSG00000173674	EIF1AX	91	93.130	ENSSARG00000013528	EIF1AX	91	93.130	Sorex_araneus
ENSG00000173674	EIF1AX	100	99.306	ENSSPUG00000018499	EIF1AY	100	99.306	Sphenodon_punctatus
ENSG00000173674	EIF1AX	100	99.306	ENSSPAG00000017728	eif1axb	100	99.306	Stegastes_partitus
ENSG00000173674	EIF1AX	100	99.306	ENSSSCG00000037509	-	98	99.306	Sus_scrofa
ENSG00000173674	EIF1AX	100	99.306	ENSSSCG00000032223	EIF1AX	100	99.306	Sus_scrofa
ENSG00000173674	EIF1AX	74	98.131	ENSTGUG00000007524	EIF1AX	100	98.131	Taeniopygia_guttata
ENSG00000173674	EIF1AX	91	91.603	ENSTRUG00000007017	eif1axb	90	91.603	Takifugu_rubripes
ENSG00000173674	EIF1AX	91	93.893	ENSTNIG00000004558	eif1axb	90	93.893	Tetraodon_nigroviridis
ENSG00000173674	EIF1AX	96	95.683	ENSTBEG00000017492	EIF1AX	100	95.683	Tupaia_belangeri
ENSG00000173674	EIF1AX	91	91.603	ENSTTRG00000002012	EIF1AX	91	91.603	Tursiops_truncatus
ENSG00000173674	EIF1AX	91	88.235	ENSUAMG00000028107	-	82	88.235	Ursus_americanus
ENSG00000173674	EIF1AX	100	99.306	ENSUAMG00000023272	-	85	99.306	Ursus_americanus
ENSG00000173674	EIF1AX	99	93.007	ENSUMAG00000010717	-	95	93.007	Ursus_maritimus
ENSG00000173674	EIF1AX	100	98.611	ENSUMAG00000019373	-	100	98.611	Ursus_maritimus
ENSG00000173674	EIF1AX	96	99.275	ENSVPAG00000009927	EIF1AX	100	99.275	Vicugna_pacos
ENSG00000173674	EIF1AX	100	99.306	ENSVVUG00000030364	-	75	99.306	Vulpes_vulpes
ENSG00000173674	EIF1AX	100	100.000	ENSVVUG00000013024	EIF1AX	100	100.000	Vulpes_vulpes
ENSG00000173674	EIF1AX	100	99.306	ENSXETG00000025347	eif1ax	100	99.306	Xenopus_tropicalis
ENSG00000173674	EIF1AX	100	98.611	ENSXCOG00000015604	eif1axb	92	98.611	Xiphophorus_couchianus
ENSG00000173674	EIF1AX	100	99.306	ENSXMAG00000021594	EIF1AY	100	99.306	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0003743	translation initiation factor activity	-	IEA	Function
GO:0005515	protein binding	21139563.23435562.23623729.	IPI	Function
GO:0005829	cytosol	-	TAS	Component
GO:0006413	translational initiation	-	TAS	Process
GO:0008135	translation factor activity, RNA binding	8106356.	TAS	Function

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

PPI

Paralogs

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.