EuRBPDB

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TCGA tumor abbreviations
  • ACCAdrenocortical carcinoma
  • BLCABladder Urothelial Carcinoma
  • BRCABreast invasive carcinoma
  • CESCCervical squamous cell carcinoma and endocervical adenocarcinoma
  • CHOLCholangio carcinoma
  • COADColon adenocarcinoma
  • DLBCLymphoid Neoplasm Diffuse Large B-cell Lymphoma
  • ESCAEsophageal carcinoma
  • GBMGlioblastoma multiforme
  • HNSCHead and Neck squamous cell carcinoma
  • KICHKidney Chromophobe
  • KIRCKidney renal clear cell carcinoma
  • KIRPKidney renal papillary cell carcinoma
  • LAMLAcute Myeloid Leukemia
  • LGGBrain Lower Grade Glioma
  • LIHCLiver hepatocellular carcinoma
  • LUADLung adenocarcinoma
  • LUSCLung squamous cell carcinoma
  • MESOMesothelioma
  • OVOvarian serous cystadenocarcinoma
  • PAADPancreatic adenocarcinoma
  • PCPGPheochromocytoma and Paraganglioma
  • PRADProstate adenocarcinoma
  • READRectum adenocarcinoma
  • SARCSarcoma
  • SKCMSkin Cutaneous Melanoma
  • STADStomach adenocarcinoma
  • TGCTThyroid carcinoma
  • THCAThyroid carcinoma
  • THYMThymoma
  • UCECUterine Corpus Endometrial Carcinoma
  • UCSUterine Carcinosarcoma
  • UVMUveal Melanoma

Note: Click here to get the extension of tumor abbreviations.


  • Cancer Related Information
  • Basic Information

Differential Expression

Expression in 33 cancers

Mutations
CancerChrPosition Mutation TypedbSNPProtein-change Allele FreqRBD
BLCAchr1151779975Nonsense_MutationnovelQ133*0.15
BLCAchr1151778791Silentrs369680847G259G0.5
BLCAchr1151776576Missense_MutationNAH303Y0.45
BLCAchr1151775821Splice_RegionnovelS427S0.16
BLCAchr1151775529Missense_MutationnovelE433Q0.33
BRCAchr1151780069SilentNAI101I0.04
BRCAchr1151776113SilentNAK400K0.14
BRCAchr1151775077Missense_MutationNAM508I0.21
BRCAchr1151780038Missense_MutationnovelK112E0.04
BRCAchr1151781493SilentnovelA73A0.09
BRCAchr1151775127Missense_Mutationrs767475622A492T0.26
BRCAchr1151778851Silentrs763419568N239N0.52
BRCAchr1151781516Missense_MutationNAL66F0.13
CESCchr1151775100Missense_Mutationrs766740216E501Q0.09
CESCchr1151778763Missense_MutationNAG269C0.04
CESCchr1151779188Frame_Shift_InsnovelT159Ifs*30.04
CESCchr1151774727Missense_MutationnovelS539F0.33
CESCchr1151780090Silentrs373154310G94G0.23
COADchr1151780026Missense_MutationnovelH116Y0.49
COADchr1151776530Missense_MutationnovelP318H0.33KH_1
COADchr1151779196SilentNAA156A0.39
COADchr1151778870Missense_MutationnovelE233G0.62
COADchr1151775152SilentnovelG483G0.28
COADchr1151778790Missense_Mutationrs201963923D260N0.39
COADchr1151775511Missense_MutationnovelF439L0.06
COADchr1151774277Intronnovel0.24
COADchr1151774289Intronnovel0.27
COADchr1151780021Missense_MutationnovelQ117H0.31
COADchr1151778791Silentrs369680847G259G0.32
COADchr1151775518Frame_Shift_InsnovelL436Ffs*30.26
COADchr1151779222Missense_MutationNAR148C0.05
COADchr1151781503Missense_Mutationrs368367936R70Q0.17
ESCAchr1151776541Silentrs773081754A314A0.24
ESCAchr1151776456Missense_MutationnovelH343N0.35KH_1
ESCAchr1151774754Frame_Shift_DelnovelT527Lfs*220.1
GBMchr1151779212Missense_MutationnovelC151S0.23
GBMchr1151780133Missense_MutationnovelK80R0.1
GBMchr1151776223Missense_MutationnovelL364I0.05KH_1
GBMchr1151782997Missense_MutationnovelT9I0.24
GBMchr1151782913Missense_MutationnovelY37F0.06
GBMchr1151782957SilentNAG22G0.05
HNSCchr1151776558Missense_Mutationrs773992753E309Q0.28KH_1
HNSCchr1151779239Missense_MutationnovelR142K0.28
HNSCchr1151778738Missense_MutationnovelD277G0.32
HNSCchr1151778843Missense_MutationnovelS242C0.14
HNSCchr1151781546Missense_MutationnovelE56Q0.23
KIRCchr1151778743SilentNAS275S0.19
KIRPchr1151775536Missense_MutationnovelQ430H0.5
LGGchr1151780018Silentrs752323682I118I0.45
LIHCchr1151779157SilentNAL169L0.14
LUADchr1151782966SilentNAL19L0.23
LUADchr1151776122SilentnovelC397C0.06
LUADchr1151775473SilentnovelL451L0.1
LUSCchr1151776443Missense_MutationnovelS347I0.16KH_1
LUSCchr1151778871Missense_MutationnovelE233K0.07
LUSCchr1151782971Missense_Mutationrs369717003A18S0.1
LUSCchr1151780108SilentnovelV88V0.72
LUSCchr1151778759Missense_MutationNAS270F0.38
LUSCchr1151780122Missense_MutationNAA84S0.53
OVchr1151778701Missense_MutationnovelE289D0.24
OVchr1151776110SilentnovelD401D0.05
OVchr1151782909SilentNAR38R0.41
OVchr1151779955SilentnovelI139I0.04
OVchr1151783010Missense_Mutationrs373623190R5W0.33
OVchr1151774469Missense_MutationnovelD557N0.1
PAADchr1151779235Silentrs751347895G143G0.16
PRADchr1151779120Missense_MutationNAE182Q0.25
PRADchr1151776191SilentNAR374R0.09
PRADchr1151780090Silentrs373154310G94G0.28
READchr1151776508SilentNAI325I0.3
READchr1151779222Missense_MutationNAR148C0.24
SARCchr1151778888Missense_MutationnovelE227G0.13
SKCMchr1151779222Missense_MutationNAR148C0.24
SKCMchr1151779222Missense_MutationNAR148C0.16
SKCMchr1151779120Missense_MutationNAE182K0.68
SKCMchr1151776169Missense_Mutationrs779627175G382R0.25KH_1
SKCMchr1151780139Missense_MutationnovelL78R0.39
SKCMchr1151774773Missense_MutationNAL524F0.29
SKCMchr1151778967Missense_Mutationrs747773276R201W0.24
SKCMchr1151779222Missense_MutationNAR148C0.23
SKCMchr1151776576Missense_MutationNAH303Y0.59
SKCMchr1151778982Missense_MutationNAE196K0.76
SKCMchr1151780069SilentNAI101I0.48
SKCMchr1151779222Missense_MutationNAR148C0.19
SKCMchr1151774789SilentnovelA518A0.17
SKCMchr1151778778Missense_MutationnovelV264I0.48
SKCMchr1151782953Missense_MutationNAP24S0.41
SKCMchr1151781534Missense_MutationNAP60S0.21
SKCMchr1151775440SilentNAG462G0.3
SKCMchr1151776199Nonsense_Mutationrs749386396R372*0.38KH_1
SKCMchr1151776199Nonsense_Mutationrs749386396R372*0.39KH_1
SKCMchr1151782910Missense_MutationNAR38K0.41
SKCMchr1151776161SilentNAL384L0.35
SKCMchr1151778835Missense_MutationNAE245K0.46
SKCMchr1151779978Missense_MutationNAP132S0.38
SKCMchr1151776508SilentNAI325I0.16
SKCMchr1151776199Nonsense_Mutationrs749386396R372*0.29KH_1
SKCMchr1151781534Missense_MutationNAP60S0.44
SKCMchr1151781544SilentNAE56E0.15
SKCMchr1151775833SilentNAR423R0.28
SKCMchr1151778804Missense_MutationnovelP255L0.36
STADchr1151781504Missense_MutationNAR70W0.24
STADchr1151775506SilentnovelD440D0.04
STADchr1151775127Missense_Mutationrs767475622A492T0.19
STADchr1151776094Splice_SiteNAX406_splice0.16
STADchr1151776221Silentrs765152360L364L0.18
STADchr1151775127Missense_Mutationrs767475622A492T0.16
UCECchr1151776508SilentNAI325I0.26
UCECchr1151774756Missense_MutationnovelK529N0.38
UCECchr1151776558Nonsense_MutationNAE309*0.4KH_1
UCECchr1151778967Missense_Mutationrs747773276R201W0.3
UCECchr1151778789Missense_MutationnovelD260G0.39
UCECchr1151778927Missense_Mutationrs191124174R214H0.44
UCECchr1151780067Missense_MutationnovelS102N0.11
UCECchr1151779007Splice_SitenovelX188_splice0.19
UCECchr1151774365Intronrs5444485820.29
UCECchr11517734963'UTRnovel0.32
UCECchr1151776458Missense_MutationnovelQ342P0.09KH_1
UCECchr1151779222Missense_MutationNAR148C0.42
UCECchr1151774709Splice_SiteNAX545_splice0.26
UCECchr1151775504Missense_MutationnovelR441K0.34
UCECchr1151778946Missense_MutationnovelA208T0.44
UCECchr1151781503Missense_Mutationrs368367936R70Q0.61
UCECchr1151775128Silentrs752865957Y491Y0.34
UCECchr11517735263'UTRnovel0.38
UCECchr1151774236Intronnovel0.5
UCECchr11517735643'UTRnovel0.45
UCECchr1151778687Missense_MutationnovelE294G0.22
UCECchr1151778973Nonsense_MutationnovelE199*0.34
UCECchr1151780136Missense_Mutationrs758798421R79Q0.3
UCECchr1151783003Missense_MutationnovelS7Y0.48
UCECchr1151775071Missense_MutationnovelK510N0.37
UCECchr1151776144Missense_MutationnovelD390G0.07KH_1
UCECchr1151775874Missense_MutationnovelL410I0.1KH_1
UCECchr1151778889Missense_MutationnovelE227K0.23
UCECchr1151781583SilentnovelE43E0.19
UCECchr1151780090Silentrs373154310G94G0.17

Copy Number Variations (CNVs)
CancerTypeFreq Q-value
ACCAMP0.14440.11282
CESCAMP0.48143.2002e-05
DLBCDEL0.04170.0017831
ESCAAMP0.40760.0022446
KIRCAMP0.09280.059566
LUSCAMP0.43311.6618e-06
PAADAMP0.21740.085665
PCPGAMP0.14810.00029562
READAMP0.26670.025154
SARCAMP0.34244.3422e-08
SKCMAMP0.48239.6912e-06
TGCTAMP0.34670.088103

Survival Analysis
CancerP-value Q-value
THYM0.026

Kaplan-Meier Survival Analysis

SKCM0.0014

Kaplan-Meier Survival Analysis

LUSC0.033

Kaplan-Meier Survival Analysis

ESCA0.022

Kaplan-Meier Survival Analysis

KIRP0.0032

Kaplan-Meier Survival Analysis

PCPG0.025

Kaplan-Meier Survival Analysis

LAML0.027

Kaplan-Meier Survival Analysis

UCEC0.00061

Kaplan-Meier Survival Analysis

LIHC0.0014

Kaplan-Meier Survival Analysis

LGG0.006

Kaplan-Meier Survival Analysis

THCA0.0041

Kaplan-Meier Survival Analysis

LUAD0.005

Kaplan-Meier Survival Analysis

Drugs

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Eesembl ID



Cell lines and drugs in GSE70138 or GSE92742

  • Description
  • RBDs
  • Literatures
  • Expression
  • Transcripts
  • Gene Model
  • Phenotypes
  • GWAS
  • PPI
  • Orthologs
  • Gene Ontology
Description
Ensembl ID
ENSG00000182134 (Gene tree)
Gene ID
11022
Gene Symbol
TDRKH
Alias
TDRD2
Full Name
tudor and KH domain containing
Gene Type
protein_coding
Species
Homo_sapiens
Status
confidence
Strand
Minus strand
Length
21,310 bases
Position
chr1:151,770,107-151,791,416
Accession
11713
RBP type
canonical RBP
Summary
(Tudor And KH Domain Containing) is a Protein Coding gene. Diseases associated with TDRKH include Ewing Sarcoma. Among its related pathways are Mitotic Prophase and Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and RNA binding. An important paralog of this gene is TDRD1.
RNA binding domains(RBDs)
Protein IDDomain Pfam IDE-value Domain number Total number
ENSP00000357812KH_1PF00013.293.1e-3312
ENSP00000357812KH_1PF00013.293.1e-3322
ENSP00000357815KH_1PF00013.293.1e-3312
ENSP00000357815KH_1PF00013.293.1e-3322
ENSP00000357819KH_1PF00013.293.1e-3312
ENSP00000357819KH_1PF00013.293.1e-3322
ENSP00000395718KH_1PF00013.293.1e-3312
ENSP00000395718KH_1PF00013.293.1e-3322
ENSP00000416645KH_1PF00013.293.8e-3312
ENSP00000416645KH_1PF00013.293.8e-3322
ENSP00000357813KH_1PF00013.291.5e-2712
ENSP00000357813KH_1PF00013.291.5e-2722
ENSP00000357817KH_1PF00013.296.8e-1911
ENSP00000431557KH_1PF00013.299.6e-1711
ENSP00000357817TUDORPF00567.245e-3011
ENSP00000357813TUDORPF00567.246.2e-3011
ENSP00000357812TUDORPF00567.246.3e-3011
ENSP00000357815TUDORPF00567.246.3e-3011
ENSP00000357819TUDORPF00567.246.3e-3011
ENSP00000395718TUDORPF00567.246.3e-3011
ENSP00000416645TUDORPF00567.246.8e-3011

Literatures on RNA binding capacity
PIDTitleArticle TimeAuthorDoi
18085409Proteomic analysis of RNA-binding proteins in dry seeds of rice after fractionation by ssDNA affinity column chromatography.Biotechnol Lett2008 MayMasaki S-
9858671Fluorescent differential display analysis of gene expression in apoptotic neuroblastoma cells.Gene1998 Nov 26Choi DK-
12530963Two RNA binding proteins, HEN4 and HUA1, act in the processing of AGAMOUS pre-mRNA in Arabidopsis thaliana.Dev Cell2003 JanCheng Y-
10564819Molecular analyses of the possible RNA-binding protein gene located in the human leukocyte antigen (HLA)--DR subregion.Gene1999 Nov 15Chida S-
19143842A neomorphic sgs3 allele stabilizing miRNA cleavage products reveals that SGS3 acts as a homodimer.FEBS J2009 FebElmayan Tdoi: 10.1111/j.1742-4658.2008.06828.x.
9143498Gene sequence, localization, and evolutionary conservation of DAZLA, a candidate male sterility gene.Genomics1997 Apr 15Seboun E-
17940093Trypanosome MTR4 is involved in rRNA processing.Nucleic Acids Res2007Cristodero M-
17617174Mutations in CHLOROPLAST RNA BINDING provide evidence for the involvement of the chloroplast in the regulation of the circadian clock in Arabidopsis.Plant J2007 AugHassidim M-
26310847Novel roles for LIX1L in promoting cancer cell proliferation through ROS1-mediated LIX1L phosphorylation.Sci Rep2015 Aug 27Nakamura Sdoi: 10.1038/srep13474.
7547471Isolation and embryonic expression of Xel-1, a nervous system-specific Xenopus gene related to the elav gene family.Mech Dev1995 JunPerron M-
7867501Patterns of localization and cytoskeletal association of two vegetally localized RNAs, Vg1 and Xcat-2.Development1995 JanForristall C-
12932328dead end, a novel vertebrate germ plasm component, is required for zebrafish primordial germ cell migration and survival.Curr Biol2003 Aug 19Weidinger G-
10842088Expression of the RNA recognition motif-containing protein SEB-4 during Xenopus embryonic development.Mech Dev2000 JunFetka I-
16872451Esg1, expressed exclusively in preimplantation embryos, germline, and embryonic stem cells, is a putative RNA-binding protein with broad RNA targets.Dev Growth Differ2006 AugTanaka TS-
20410137Mug28, a meiosis-specific protein of Schizosaccharomyces pombe, regulates spore wall formation.Mol Biol Cell2010 Jun 15Shigehisa Adoi: 10.1091/mbc.E09-12-0997
25604992Identification of genes that may regulate the expression of the transcription factor production of anthocyanin pigment 1 (PAP1)/MYB75 involved in Arabidopsis anthocyanin biosynthesis.Plant Cell Rep2015 MayShin DHdoi: 10.1007/s00299-015-1743-7
28656601Silencing of AtRAP, a target gene of a bacteria-induced small RNA, triggers antibacterial defense responses through activation of LSU2 and down-regulation of GLK1.New Phytol2017 AugWang Hdoi: 10.1111/nph.14654
11342549A novel nucleolar protein, NIFK, interacts with the forkhead associated domain of Ki-67 antigen in mitosis.J Biol Chem2001 Jul 6Takagi M-
16772403The nucleolar protein Esf2 interacts directly with the DExD/H box RNA helicase, Dbp8, to stimulate ATP hydrolysis.Nucleic Acids Res2006 Jun 13Granneman S-
21284850Analysis of electric moments of RNA-binding proteins: implications for mechanism and prediction.BMC Struct Biol2011 Feb 1Ahmad Sdoi: 10.1186/1472-6807-11-8.
7503813EWS/Fli-1 chimeric protein is a transcriptional activator.Cancer Res1993 Dec 15Ohno T-
7499316Cloning of a novel RNA binding polypeptide (RA301) induced by hypoxia/reoxygenation.J Biol Chem1995 Nov 24Matsuo N-
10199401NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation.Cell1999 Apr 2Yamaguchi Y-
10096065The RNA-binding protein gene, hermes, is expressed at high levels in the developing heart.Mech Dev1999 JanGerber WV-
9848653Cbf5p, a potential pseudouridine synthase, and Nhp2p, a putative RNA-binding protein, are present together with Gar1p in all H BOX/ACA-motif snoRNPs and constitute a common bipartite structure.RNA1998 DecWatkins NJ-
3144434The sex-determining gene tra-2 of Drosophila encodes a putative RNA binding protein.Cell1988 Dec 23Amrein H-
9799600Four ubiquitously expressed genes, RD (D6S45)-SKI2W (SKIV2L)-DOM3Z-RP1 (D6S60E), are present between complement component genes factor B and C4 in the class III region of the HLA.Genomics1998 Nov 1Yang Z-
2026327Autoregulation of the splicing of transcripts from the transformer-2 gene of Drosophila.Genes Dev1991 MayMattox W-
1708282A developmentally regulated, nervous system-specific gene in Xenopus encodes a putative RNA-binding protein.New Biol1990 JunRichter K-
9655917Cloning and sequencing of the cDNA for an RNA-binding protein from the Mexican axolotl: binding affinity of the in vitro synthesized protein.Biochim Biophys Acta1998 Jul 9Bhatia R-
9394616The chromosomal signal for sex determination in Caenorhabditis elegans.Bioessays1997 NovMeneely PM-
9334257Identification of several human homologs of hamster DNA damage-inducible transcripts. Cloning and characterization of a novel UV-inducible cDNA that codes for a putative RNA-binding protein.J Biol Chem1997 Oct 17Sheikh MS-
9344542A novel KH-domain protein mediates cell adhesion processes in Drosophila.Dev Biol1997 Oct 15Lo PC-
9303534The KH domain protein encoded by quaking functions as a dimer and is essential for notochord development in Xenopus embryos.Genes Dev1997 Sep 1Zorn AM-
9254700Sce3, a suppressor of the Schizosaccharomyces pombe septation mutant cdc11, encodes a putative RNA-binding protein.Nucleic Acids Res1997 Sep 1Schmidt S-
9214641Mex67p, a novel factor for nuclear mRNA export, binds to both poly(A)+ RNA and nuclear pores.EMBO J1997 Jun 2Segref A-
9217163X-chromosome-counting mechanisms that determine nematode sex.Nature1997 Jul 10Nicoll M-
9169854The held out wings (how) Drosophila gene encodes a putative RNA-binding protein involved in the control of muscular and cardiac activity.Development1997 MayZaffran S-
9120432Regulation of a specific circadian clock output pathway by lark, a putative RNA-binding protein with repressor activity.J Neurobiol1996 SepNewby LM-
8948583GLD-1, a cytoplasmic protein essential for oocyte differentiation, shows stage- and sex-specific expression during Caenorhabditis elegans germline development.Dev Biol1996 Nov 25Jones AR-
8954779Cloning and mapping of a human RBP56 gene encoding a putative RNA binding protein similar to FUS/TLS and EWS proteins.Genomics1996 Nov 15Morohoshi F-
8923298Temporally manipulated rescue of visual and courtship abnormalities caused by a nonA mutation in Drosophila.J Neurogenet1996 SepRendahl KG-
8778301Defects in courtship and vision caused by amino acid substitutions in a putative RNA-binding protein encoded by the no-on-transient A (nonA) gene of Drosophila.J Neurosci1996 Feb 15Rendahl KG-
8661148Mouse autosomal homolog of DAZ, a candidate male sterility gene in humans, is expressed in male germ cells before and after puberty.Genomics1996 Jul 15Reijo R-
8573167PIPPin, a putative RNA-binding protein specifically expressed in the rat brain.Biochem Biophys Res Commun1996 Jan 5Castiglia D-
8336942Analysis of the DNA-binding and transcriptional activation functions of human Fli-1 protein.Oncogene1993 AugRao VN-
8224861The Saccharomyces cerevisiae MTS1 gene encodes a putative RNA-binding protein involved in mitochondrial protein targeting.Gene1993 Oct 15Ellis EM-
8241770Segmentation of the Drosophila embryo.Curr Opin Genet Dev1993 AugKornberg TB-
10331608Search for a Caenorhabditis elegans FMR1 homologue: identification of a new putative RNA-binding protein (PRP-1) that hybridizes to the mouse FMR1 double K homology domain.Am J Med Genet1999 May 28Shtang S-
8043282Musashi, a neural RNA-binding protein required for Drosophila adult external sensory organ development.Neuron1994 JulNakamura M-
7941739Organization of the centromeric region of chromosome XIV in Saccharomyces cerevisiae.Yeast1994 AprLalo D-
7829090Cloning and chromosome localization of the mouse Ews gene.Genomics1994 Sep 1Plougastel B-
16541125Leafy head2, which encodes a putative RNA-binding protein, regulates shoot development of rice.Cell Res2006 MarXiong GS-
12649177A novel gene, MSI2, encoding a putative RNA-binding protein is recurrently rearranged at disease progression of chronic myeloid leukemia and forms a fusion gene with HOXA9 as a result of the cryptic t(7;17)(p15;q23).Cancer Res2003 Mar 15Barbouti A-
16528049Purification and characterization of infectious myonecrosis virus of penaeid shrimp.J Gen Virol2006 AprPoulos BT-
12397108MEC-8 regulates alternative splicing of unc-52 transcripts in C. elegans hypodermal cells.Development2002 NovSpike CA-
12360533Structure of HI1333 (YhbY), a putative RNA-binding protein from Haemophilus influenzae.Proteins2002 Nov 15Willis MA-
11940650Evidence that negative elongation factor represses transcription elongation through binding to a DRB sensitivity-inducing factor/RNA polymerase II complex and RNA.Mol Cell Biol2002 MayYamaguchi Y-
11813105Nucleotide variation at the no-on-transient A gene in Drosophila littoralis.Heredity (Edinb)2002 JanHuttunen S-
11685576Spatio-temporal expression of a gene encoding a putative RNA-binding protein during the early larval development of the mollusc Patella vulgata.Dev Genes Evol2001 SepKlerkx AH-
11438655Analysis of smu-1, a gene that regulates the alternative splicing of unc-52 pre-mRNA in Caenorhabditis elegans.Mol Cell Biol2001 AugSpike CA-
11170747Characterization of a widely expressed gene (LUC7-LIKE; LUC7L) defining the centromeric boundary of the human alpha-globin domain.Genomics2001 Feb 1Tufarelli C-
10806425An RNA-binding protein homologue that promotes sporulation-specific gene expression in Saccharomyces cerevisiae.Yeast2000 MaySoushko M-
16896214Spo5/Mug12, a putative meiosis-specific RNA-binding protein, is essential for meiotic progression and forms Mei2 dot-like nuclear foci.Eukaryot Cell2006 AugKasama T-
16329940Retrieval of first genome data for rice cluster I methanogens by a combination of cultivation and molecular techniques.FEMS Microbiol Ecol2005 Jul 1Erkel C-
10602519Fusion of the RBP56 and CHN genes in extraskeletal myxoid chondrosarcomas with translocation t(9;17)(q22;q11).Oncogene1999 Dec 9Panagopoulos I-
15917470Stimulation of Oct-4 activity by Ewing's sarcoma protein.Stem Cells2005 Jun-JulLee J-
15310842Regulation of flowering time in Arabidopsis by K homology domain proteins.Proc Natl Acad Sci U S A2004 Aug 24Mockler TC-
15213438Solution structure of the hypothetical protein SAV1595 from Staphylococcus aureus, a putative RNA binding protein.J Biomol NMR2004 JulLiu D-
15166138A novel gene, msa1, inhibits sexual differentiation in Schizosaccharomyces pombe.Genetics2004 MayJeong HT-
15010206A collection of cDNAs enriched in upper cortical layers of the embryonic mouse brain.Brain Res Mol Brain Res2004 Mar 30Garcia-Frigola C-
14973162A new Arabidopsis gene, FLK, encodes an RNA binding protein with K homology motifs and regulates flowering time via FLOWERING LOCUS C.Plant Cell2004 MarLim MH-
14563563Genetic analysis of an important oxidative stress locus in the anaerobe Bacteroides fragilis.Gene2003 Oct 16Herren CD-
23110899Mutation of Arabidopsis spliceosomal timekeeper locus1 causes circadian clock defects.Plant Cell2012 OctJones MAdoi: 10.1105/tpc.112.104828
23087326A KH domain-containing putative RNA-binding protein is critical for heat stress-responsive gene regulation and thermotolerance in Arabidopsis.Mol Plant2013 MarGuan Qdoi: 10.1093/mp/sss119
19639222The effect of cadmium on brain cells in culture.Int J Mol Med2009 SepGerspacher C-
23040517An ABA-regulated putative RNA-binding protein affects seed germination of Arabidopsis under ABA or abiotic stress conditions.J Plant Physiol2013 Jan 15Jung HJdoi: 10.1016/j.jplph.2012.09.002
19168622Overexpression of MazFsa in Staphylococcus aureus induces bacteriostasis by selectively targeting mRNAs for cleavage.J Bacteriol2009 AprFu Zdoi: 10.1128/JB.00907-08
19081077The conserved protein SZY-20 opposes the Plk4-related kinase ZYG-1 to limit centrosome size.Dev Cell2008 DecSong MHdoi: 10.1016/j.devcel.2008.09.018.
18705885A putative RNA-binding protein has a role in virulence in Ralstonia solanacearum GMI1000.Mol Plant Pathol2008 JanFranks Adoi: 10.1111/j.1364-3703.2007.00442.x.
17932509Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells.EMBO Rep2007 NovHock J-
17415412Ewing sarcoma gene EWS is essential for meiosis and B lymphocyte development.J Clin Invest2007 MayLi H-
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Expression
Transcripts
Transcript IDNameLengthRefSeq ID Protein IDLengthRefSeq IDUniportKB ID
ENST00000368827TDRKH-2052318XM_017000126ENSP00000357819561 (aa)XP_016855615Q9Y2W6
ENST00000368824TDRKH-2032824XM_017000122ENSP00000357815561 (aa)XP_016855611Q9Y2W6
ENST00000368825TDRKH-2042651XM_005244856ENSP00000357817516 (aa)XP_005244913Q9Y2W6
ENST00000368822TDRKH-2013093-ENSP00000357812561 (aa)-Q9Y2W6
ENST00000368823TDRKH-2022751-ENSP00000357813557 (aa)-Q5SZR4
ENST00000484421TDRKH-209862--- (aa)--
ENST00000463553TDRKH-208371--- (aa)--
ENST00000486986TDRKH-210760--- (aa)--
ENST00000458431TDRKH-2072768XM_017000124ENSP00000395718561 (aa)XP_016855613Q9Y2W6
ENST00000440583TDRKH-2062296-ENSP00000416645605 (aa)-F6TB26
ENST00000494725TDRKH-211548--- (aa)--
ENST00000530202TDRKH-215477-ENSP0000043245258 (aa)-E9PQX4
ENST00000526413TDRKH-2141807-ENSP00000433678140 (aa)-B7ZAG4
ENST00000525790TDRKH-2122217-ENSP00000437147140 (aa)-B7ZAG4
ENST00000526378TDRKH-213568-ENSP00000431557131 (aa)-E9PKN8
Gene Model
Click here to download ENSG00000182134's gene model file
Phenotypes
ensgIDTraitpValuePubmed ID
ENSG00000182134Triglycerides1.23020318463272E-2117903299
ENSG00000182134Lipids1.77177900746748E-617903299
ENSG00000182134Hemoglobins3.87474530679068E-1317903294
ENSG00000182134Hemoglobins9.82361694088194E-817903294
GWAS
ensgIDSNPChromosomePositionSNP-risk TraitPubmedID95% CIOr or BEAT EFO ID
ENSG00000182134rs48455701151786628TCoronary artery disease29212778[0.04-0.076] unit increase0.058EFO_0000378
ENSG00000182134rs118105711151789832CCoronary artery disease29212778[0.039-0.071] unit decrease0.0553EFO_0000378
Protein-Protein Interaction (PPI)

Clik here to download ENSG00000182134's network

* RBP PPI network refers to all genes directly bind to RBP
Orthologs
Ensembl IDGene SymbolCoverageIdentiy OrthologGene SymbolCoverageIdentiy Species
ENSG00000182134TDRKH100100.000ENSAMEG00000000421TDRKH10089.894Ailuropoda_melanoleuca
ENSG00000182134TDRKH10062.595ENSACAG00000007457TDRKH9556.967Anolis_carolinensis
ENSG00000182134TDRKH10097.710ENSANAG00000021663TDRKH10096.078Aotus_nancymaae
ENSG00000182134TDRKH10098.473ENSBTAG00000021594TDRKH10090.731Bos_taurus
ENSG00000182134TDRKH10098.473ENSCJAG00000007955TDRKH10096.435Callithrix_jacchus
ENSG00000182134TDRKH10099.237ENSCAFG00000012856TDRKH10091.312Canis_familiaris
ENSG00000182134TDRKH10099.237ENSCAFG00020009606TDRKH10091.312Canis_lupus_dingo
ENSG00000182134TDRKH10098.473ENSCHIG00000025326TDRKH10090.731Capra_hircus
ENSG00000182134TDRKH10098.473ENSTSYG00000010405TDRKH10091.979Carlito_syrichta
ENSG00000182134TDRKH10098.473ENSCAPG00000007565TDRKH9788.132Cavia_aperea
ENSG00000182134TDRKH10098.473ENSCPOG00000003556TDRKH10090.196Cavia_porcellus
ENSG00000182134TDRKH10097.710ENSCCAG00000033931TDRKH10095.900Cebus_capucinus
ENSG00000182134TDRKH10099.237ENSCATG00000041878TDRKH10098.396Cercocebus_atys
ENSG00000182134TDRKH10096.947ENSCLAG00000001088TDRKH10088.948Chinchilla_lanigera
ENSG00000182134TDRKH10099.237ENSCSAG00000001820TDRKH10098.574Chlorocebus_sabaeus
ENSG00000182134TDRKH9586.232ENSCHOG00000000264TDRKH8886.998Choloepus_hoffmanni
ENSG00000182134TDRKH10080.916ENSCPBG00000008824TDRKH9063.768Chrysemys_picta_bellii
ENSG00000182134TDRKH10097.710ENSCANG00000037367TDRKH10096.970Colobus_angolensis_palliatus
ENSG00000182134TDRKH9696.032ENSCGRG00001006583-9989.693Cricetulus_griseus_chok1gshd
ENSG00000182134TDRKH9650.794ENSCGRG00001010793-9063.799Cricetulus_griseus_chok1gshd
ENSG00000182134TDRKH9685.714ENSCGRG00001011699-9964.815Cricetulus_griseus_chok1gshd
ENSG00000182134TDRKH9685.714ENSCGRG00000013230-9964.630Cricetulus_griseus_crigri
ENSG00000182134TDRKH9696.032ENSCGRG00000012937-9989.693Cricetulus_griseus_crigri
ENSG00000182134TDRKH9650.000ENSCGRG00000012138-9063.441Cricetulus_griseus_crigri
ENSG00000182134TDRKH10099.237ENSDNOG00000035650TDRKH10087.984Dasypus_novemcinctus
ENSG00000182134TDRKH10098.473ENSDORG00000015322Tdrkh10092.513Dipodomys_ordii
ENSG00000182134TDRKH10089.313ENSETEG00000008020TDRKH10081.915Echinops_telfairi
ENSG00000182134TDRKH9532.639ENSEBUG00000010481TDRKH8335.867Eptatretus_burgeri
ENSG00000182134TDRKH10098.473ENSEASG00005005213TDRKH10091.087Equus_asinus_asinus
ENSG00000182134TDRKH10098.473ENSECAG00000013096TDRKH10091.444Equus_caballus
ENSG00000182134TDRKH10096.183ENSEEUG00000015952TDRKH7296.429Erinaceus_europaeus
ENSG00000182134TDRKH100100.000ENSFCAG00000010980TDRKH10090.764Felis_catus
ENSG00000182134TDRKH10094.656ENSFDAG00000015315TDRKH10089.127Fukomys_damarensis
ENSG00000182134TDRKH10058.333ENSGALG00000031812TDRKH9655.797Gallus_gallus
ENSG00000182134TDRKH10081.679ENSGAGG00000005447TDRKH10063.194Gopherus_agassizii
ENSG00000182134TDRKH10099.287ENSGGOG00000025419TDRKH10099.287Gorilla_gorilla
ENSG00000182134TDRKH10093.130ENSHGLG00000007478TDRKH10088.810Heterocephalus_glaber_female
ENSG00000182134TDRKH10093.130ENSHGLG00100007927TDRKH10088.810Heterocephalus_glaber_male
ENSG00000182134TDRKH10099.237ENSSTOG00000006506TDRKH10092.335Ictidomys_tridecemlineatus
ENSG00000182134TDRKH10094.656ENSJJAG00000000323Tdrkh10088.810Jaculus_jaculus
ENSG00000182134TDRKH9566.154ENSLACG00000017639TDRKH9855.854Latimeria_chalumnae
ENSG00000182134TDRKH10093.893ENSLAFG00000006274TDRKH10087.567Loxodonta_africana
ENSG00000182134TDRKH10099.237ENSMFAG00000041641TDRKH10098.574Macaca_fascicularis
ENSG00000182134TDRKH10099.237ENSMMUG00000009096TDRKH9898.611Macaca_mulatta
ENSG00000182134TDRKH10099.237ENSMNEG00000021524TDRKH10098.574Macaca_nemestrina
ENSG00000182134TDRKH10099.237ENSMLEG00000033882TDRKH10098.396Mandrillus_leucophaeus
ENSG00000182134TDRKH5060.595ENSMGAG00000017286TDRKH9460.595Meleagris_gallopavo
ENSG00000182134TDRKH10094.656ENSMAUG00000019159Tdrkh10088.372Mesocricetus_auratus
ENSG00000182134TDRKH10079.389ENSMICG00000042330-10075.714Microcebus_murinus
ENSG00000182134TDRKH100100.000ENSMICG00000010682-10093.939Microcebus_murinus
ENSG00000182134TDRKH10097.710ENSMOCG00000002113-9983.333Microtus_ochrogaster
ENSG00000182134TDRKH10075.573ENSMOCG00000014074-9964.884Microtus_ochrogaster
ENSG00000182134TDRKH10093.893ENSMODG00000018906TDRKH9682.250Monodelphis_domestica
ENSG00000182134TDRKH10098.473MGP_CAROLIEiJ_G0025310Tdrkh10091.250Mus_caroli
ENSG00000182134TDRKH10098.473ENSMUSG00000041912Tdrkh10091.429Mus_musculus
ENSG00000182134TDRKH10098.473MGP_PahariEiJ_G0026753Tdrkh9992.517Mus_pahari
ENSG00000182134TDRKH10098.473MGP_SPRETEiJ_G0026252Tdrkh10091.250Mus_spretus
ENSG00000182134TDRKH100100.000ENSMPUG00000003558TDRKH10090.231Mustela_putorius_furo
ENSG00000182134TDRKH10096.947ENSMLUG00000002213TDRKH10088.414Myotis_lucifugus
ENSG00000182134TDRKH10096.947ENSNGAG00000017825Tdrkh10091.250Nannospalax_galili
ENSG00000182134TDRKH10099.237ENSNLEG00000010284TDRKH10098.574Nomascus_leucogenys
ENSG00000182134TDRKH9493.506ENSMEUG00000006144TDRKH8993.506Notamacropus_eugenii
ENSG00000182134TDRKH8788.889ENSOPRG00000016049TDRKH8188.889Ochotona_princeps
ENSG00000182134TDRKH10096.947ENSODEG00000009532-10088.414Octodon_degus
ENSG00000182134TDRKH10091.603ENSODEG00000001075-10086.894Octodon_degus
ENSG00000182134TDRKH6272.340ENSOANG00000001094-8872.340Ornithorhynchus_anatinus
ENSG00000182134TDRKH10091.603ENSOCUG00000001387TDRKH10078.788Oryctolagus_cuniculus
ENSG00000182134TDRKH10092.366ENSOGAG00000001839-9982.540Otolemur_garnettii
ENSG00000182134TDRKH10076.122ENSOGAG00000032601-10076.122Otolemur_garnettii
ENSG00000182134TDRKH9679.365ENSOGAG00000030085-9774.653Otolemur_garnettii
ENSG00000182134TDRKH10098.473ENSOARG00000021052TDRKH10090.731Ovis_aries
ENSG00000182134TDRKH100100.000ENSPPAG00000028994TDRKH10099.287Pan_paniscus
ENSG00000182134TDRKH100100.000ENSPPRG00000001585TDRKH10091.119Panthera_pardus
ENSG00000182134TDRKH100100.000ENSPTIG00000019916TDRKH10091.119Panthera_tigris_altaica
ENSG00000182134TDRKH100100.000ENSPTRG00000001297TDRKH10099.287Pan_troglodytes
ENSG00000182134TDRKH10099.237ENSPANG00000001986TDRKH10098.574Papio_anubis
ENSG00000182134TDRKH10077.863ENSPSIG00000008541TDRKH10062.384Pelodiscus_sinensis
ENSG00000182134TDRKH10098.473ENSPEMG00000011171Tdrkh10091.964Peromyscus_maniculatus_bairdii
ENSG00000182134TDRKH10092.366ENSPCIG00000021201TDRKH9982.632Phascolarctos_cinereus
ENSG00000182134TDRKH10099.287ENSPPYG00000000855TDRKH10099.287Pongo_abelii
ENSG00000182134TDRKH10099.237ENSPCOG00000027505TDRKH10091.622Propithecus_coquereli
ENSG00000182134TDRKH10088.550ENSPVAG00000005234TDRKH10086.096Pteropus_vampyrus
ENSG00000182134TDRKH10098.473ENSRNOG00000020860Tdrkh10092.500Rattus_norvegicus
ENSG00000182134TDRKH10098.473ENSRBIG00000044860TDRKH10097.683Rhinopithecus_bieti
ENSG00000182134TDRKH10098.473ENSRROG00000036923TDRKH10097.683Rhinopithecus_roxellana
ENSG00000182134TDRKH10098.473ENSSBOG00000034454TDRKH10075.223Saimiri_boliviensis_boliviensis
ENSG00000182134TDRKH10094.656ENSSHAG00000015859TDRKH8882.716Sarcophilus_harrisii
ENSG00000182134TDRKH10098.473ENSSARG00000008525TDRKH10078.571Sorex_araneus
ENSG00000182134TDRKH10077.099ENSSPUG00000002369TDRKH9761.798Sphenodon_punctatus
ENSG00000182134TDRKH10097.710ENSSSCG00000027770TDRKH10089.606Sus_scrofa
ENSG00000182134TDRKH10097.710ENSTBEG00000011201TDRKH10091.622Tupaia_belangeri
ENSG00000182134TDRKH10082.353ENSTTRG00000003149TDRKH10082.353Tursiops_truncatus
ENSG00000182134TDRKH100100.000ENSUAMG00000019589TDRKH10089.876Ursus_americanus
ENSG00000182134TDRKH100100.000ENSUMAG00000001456TDRKH10090.053Ursus_maritimus
ENSG00000182134TDRKH10098.473ENSVPAG00000000666TDRKH10091.444Vicugna_pacos
ENSG00000182134TDRKH10099.237ENSVVUG00000013241TDRKH10091.652Vulpes_vulpes
ENSG00000182134TDRKH8740.625ENSXETG00000019909tdrkh8740.430Xenopus_tropicalis
Gene Ontology
Go IDGo_termPubmedIDEvidenceCategory
GO:0003723RNA binding-IEAFunction
GO:0005739mitochondrion-ISSComponent
GO:0007140male meiotic nuclear division-ISSProcess
GO:0007283spermatogenesis-ISSProcess
GO:0009566fertilization-ISSProcess
GO:0030154cell differentiation-IEAProcess
GO:0031047gene silencing by RNA-IEAProcess
GO:0034587piRNA metabolic process-ISSProcess
GO:0043046DNA methylation involved in gamete generation-ISSProcess
GO:0071546pi-body-ISSComponent
GO:0071547piP-body-ISSComponent
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