EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
26282217	MiR-661 contributed to cell proliferation of human ovarian cancer cells by repressing INPP5J expression.	Biomed Pharmacother	2015 Oct	Zhu T	doi: 10.1016/j.biopha.2015.07.023
26267533	The Inositol Polyphosphate 5-Phosphatase PIPP Regulates AKT1-Dependent Breast Cancer Growth and Metastasis.	Cancer Cell	2015 Aug 10	Ooms LM	doi: 10.1016/j.ccell.2015.07.003.

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr22	31127902	Intron	novel		0.6
BLCA	chr22	31126463	Missense_Mutation	NA	S453R	0.32
BLCA	chr22	31126357	Intron	novel		0.27
BRCA	chr22	31133485	Splice_Site	NA	X803_splice	0.16
BRCA	chr22	31128142	Intron	novel		0.13
BRCA	chr22	31128143	Intron	novel		0.13
BRCA	chr22	31128548	Nonsense_Mutation	NA	S696*	0.14
BRCA	chr22	31126405	Missense_Mutation	NA	T434N	0.13
BRCA	chr22	31126482	Missense_Mutation	rs767028605	A460T	0.27
BRCA	chr22	31127355	Splice_Site	novel	X538_splice	0.45
CESC	chr22	31134065	Silent	rs374129564	P889P	0.29
CESC	chr22	31127372	Missense_Mutation	rs529365616	V543M	0.28
CESC	chr22	31125565	Missense_Mutation	novel	R276G	0.16	Exo_endo_phos
CESC	chr22	31125313	Nonsense_Mutation	NA	E192*	0.21	Exo_endo_phos
CESC	chr22	31127902	Intron	novel		0.33
CESC	chr22	31126869	Intron	NA		0.44
CHOL	chr22	31125350	Missense_Mutation	novel	P204L	0.27	Exo_endo_phos
COAD	chr22	31133205	Silent	NA	R767R	0.44
COAD	chr22	31128197	Intron	novel		0.06
COAD	chr22	31133416	Missense_Mutation	rs759418802	R781H	0.32
COAD	chr22	31127970	Missense_Mutation	NA	D603N	0.38
COAD	chr22	31127982	Missense_Mutation	rs369582455	R607C	0.2
COAD	chr22	31133442	Missense_Mutation	NA	V790I	0.08
COAD	chr22	31128204	Intron	novel		0.31
COAD	chr22	31126869	Intron	NA		0.35
COAD	chr22	31127891	Intron	novel		0.07
COAD	chr22	31126973	Missense_Mutation	NA	Y516C	0.43
COAD	chr22	31128503	Missense_Mutation	rs374379847	R681H	0.15
COAD	chr22	31127015	Missense_Mutation	rs760092310	R530H	0.11
COAD	chr22	31133815	Intron	novel		0.46
COAD	chr22	31128108	Intron	rs751672094		0.18
COAD	chr22	31123109	Missense_Mutation	NA	A32V	0.23	Exo_endo_phos
COAD	chr22	31133107	Missense_Mutation	NA	R735G	0.09
COAD	chr22	31134150	Missense_Mutation	novel	R918C	0.33
COAD	chr22	31134440	3'UTR	novel		0.22
COAD	chr22	31133223	Silent	rs767376371	I773I	0.2
COAD	chr22	31127387	Missense_Mutation	NA	A548T	0.17
COAD	chr22	31127015	Missense_Mutation	rs760092310	R530H	0.19
GBM	chr22	31127372	Missense_Mutation	rs529365616	V543M	0.42
GBM	chr22	31127959	Missense_Mutation	NA	F599Y	0.88
GBM	chr22	31126448	Silent	rs779254212	G448G	0.17
GBM	chr22	31127950	Splice_Site	novel	X596_splice	0.16
GBM	chr22	31127510	Missense_Mutation	rs772172960	A589T	0.67
GBM	chr22	31128571	Nonsense_Mutation	NA	Q704*	0.45
GBM	chr22	31133621	Missense_Mutation	novel	S807R	0.14
HNSC	chr22	31126704	Missense_Mutation	novel	P493S	0.21
HNSC	chr22	31133926	Missense_Mutation	novel	S843F	0.38
HNSC	chr22	31126464	Missense_Mutation	rs150976596	D454N	0.06
HNSC	chr22	31126429	Missense_Mutation	novel	T442I	0.08
HNSC	chr22	31127324	Intron	novel		0.46
HNSC	chr22	31126010	Missense_Mutation	novel	R424L	0.43
HNSC	chr22	31126011	Splice_Site	novel	X424_splice	0.36
HNSC	chr22	31124897	Missense_Mutation	rs763939360	S53L	0.23	Exo_endo_phos
HNSC	chr22	31126659	Missense_Mutation	novel	L478F	0.22
KIRC	chr22	31125884	Missense_Mutation	novel	R382K	0.36
KIRP	chr22	31128156	Intron	novel		0.31
KIRP	chr22	31134000	Missense_Mutation	NA	L868F	0.21
KIRP	chr22	31127962	Missense_Mutation	NA	W600S	0.43
KIRP	chr22	31133912	Splice_Site	novel	X839_splice	0.56
LAML	chr22	31126475	Silent	novel	D457D	0.05
LGG	chr22	31126457	Silent	rs773142651	D451D	0.37
LIHC	chr22	31125219	Silent	novel	A160A	0.52
LIHC	chr22	31133885	Intron	novel		0.3
LUAD	chr22	31126661	Silent	novel	L478L	0.44
LUAD	chr22	31127968	Missense_Mutation	NA	G602V	0.3
LUAD	chr22	31133615	Silent	novel	T805T	0.2
LUAD	chr22	31128571	Missense_Mutation	novel	Q704K	0.19
LUAD	chr22	31133939	Silent	NA	A847A	0.44
LUSC	chr22	31128535	Missense_Mutation	novel	G692C	0.16
LUSC	chr22	31128248	Missense_Mutation	NA	K645R	0.15
LUSC	chr22	31133792	Intron	novel		0.17
LUSC	chr22	31126947	Silent	novel	V507V	0.27
PAAD	chr22	31127366	Missense_Mutation	rs540212879	G541S	0.18
PAAD	chr22	31133989	Missense_Mutation	novel	S864N	0.09
PRAD	chr22	31134096	Missense_Mutation	NA	R900W	0.5
PRAD	chr22	31124912	Missense_Mutation	novel	A58V	0.54	Exo_endo_phos
READ	chr22	31133169	Silent	rs544342010	A755A	0.47
READ	chr22	31124928	Silent	novel	G63G	0.42
SARC	chr22	31127811	Intron	novel		0.45
SKCM	chr22	31125835	Missense_Mutation	NA	P366S	0.21
SKCM	chr22	31126482	Missense_Mutation	rs767028605	A460T	0.25
SKCM	chr22	31126878	Intron	novel		0.25
SKCM	chr22	31126879	Intron	novel		0.17
SKCM	chr22	31126002	Silent	rs551093566	P421P	0.56
SKCM	chr22	31126002	Silent	rs551093566	P421P	0.46
SKCM	chr22	31128558	Silent	NA	K699K	0.48
SKCM	chr22	31125811	Missense_Mutation	rs752788280	R358C	0.29
SKCM	chr22	31128568	Missense_Mutation	NA	L703F	0.31
SKCM	chr22	31126691	Missense_Mutation	NA	M488I	0.27
SKCM	chr22	31133742	Intron	novel		0.55
SKCM	chr22	31133906	Splice_Region	novel		0.46
SKCM	chr22	31133427	Missense_Mutation	NA	D785N	0.45
SKCM	chr22	31126365	Intron	novel		0.27
SKCM	chr22	31126394	Nonsense_Mutation	NA	W430*	0.32
SKCM	chr22	31126768	Intron	novel		0.39
SKCM	chr22	31128544	Missense_Mutation	rs745466849	P695S	0.38
SKCM	chr22	31125807	Silent	rs765710038	P356P	0.33
SKCM	chr22	31133483	Missense_Mutation	rs5997883	Q803H	0.48
SKCM	chr22	31125875	Missense_Mutation	novel	G379E	0.25
SKCM	chr22	31133917	Missense_Mutation	rs200880716	S840L	0.23
SKCM	chr22	31125965	Missense_Mutation	NA	S409F	0.38
SKCM	chr22	31127893	Intron	novel		0.43
SKCM	chr22	31133906	Splice_Region	novel		0.26
SKCM	chr22	31128604	Missense_Mutation	NA	E715K	0.39
SKCM	chr22	31126715	Silent	rs371594436	F496F	0.38
STAD	chr22	31126421	Silent	rs751134714	D439D	0.14
STAD	chr22	31133099	Missense_Mutation	novel	F732S	0.3
STAD	chr22	31126002	Silent	rs551093566	P421P	0.4
STAD	chr22	31125812	Missense_Mutation	rs201675306	R358H	0.27
STAD	chr22	31126667	Silent	rs753469127	T480T	0.19
STAD	chr22	31127371	Silent	rs560088748	G542G	0.3
STAD	chr22	31134018	Missense_Mutation	NA	R874C	0.29
STAD	chr22	31128023	Silent	NA	I620I	0.35
STAD	chr22	31127382	Missense_Mutation	rs180831123	R546H	0.34
UCEC	chr22	31125776	Missense_Mutation	rs762412525	R346Q	0.27
UCEC	chr22	31126928	Missense_Mutation	rs762702897	S501L	0.4
UCEC	chr22	31133917	Missense_Mutation	rs200880716	S840L	0.23
UCEC	chr22	31133199	Silent	rs371320449	F765F	0.33
UCEC	chr22	31133657	Silent	NA	I819I	0.34
UCEC	chr22	31128060	Nonsense_Mutation	novel	Q633*	0.19
UCEC	chr22	31125194	Frame_Shift_Ins	novel	*V153Sfs40**	0.44	Exo_endo_phos
UCEC	chr22	31126656	Missense_Mutation	novel	A477T	0.41
UCEC	chr22	31123073	Missense_Mutation	novel	S20Y	0.46
UCEC	chr22	31126466	Silent	rs752568470	D454D	0.35
UCEC	chr22	31133204	Missense_Mutation	rs768633050	R767H	0.2
UCEC	chr22	31133657	Silent	NA	I819I	0.15
UCEC	chr22	31127906	Intron	NA		0.55
UCEC	chr22	31126659	Missense_Mutation	novel	L478I	0.14
UCEC	chr22	31126732	Intron	novel		0.39
UCEC	chr22	31127015	Missense_Mutation	rs760092310	R530H	0.45
UCEC	chr22	31134347	Silent	novel	A983A	0.44
UCEC	chr22	31126696	Missense_Mutation	rs757811420	A490V	0.41
UCEC	chr22	31128316	Missense_Mutation	novel	D668N	0.47
UCEC	chr22	31134045	Nonsense_Mutation	rs750558234	R883*	0.51
UCEC	chr22	31128024	Missense_Mutation	rs775173716	D621N	0.55
UCEC	chr22	31125096	Silent	novel	S119S	0.2
UCEC	chr22	31133183	Missense_Mutation	rs199693963	R760H	0.27
UCEC	chr22	31128482	Missense_Mutation	rs199529595	R674Q	0.44
UCEC	chr22	31123113	Silent	novel	P33P	0.37
UCEC	chr22	31126962	Silent	rs765371794	F512F	0.24
UCEC	chr22	31125043	Missense_Mutation	rs546477641	R102C	0.55	Exo_endo_phos
UCEC	chr22	31126381	Missense_Mutation	novel	T426N	0.09
UCEC	chr22	31125776	Missense_Mutation	rs762412525	R346Q	0.4
UCEC	chr22	31128136	Intron	novel		0.3
UCEC	chr22	31127378	Missense_Mutation	rs371488095	V545M	0.7
UCEC	chr22	31133741	Intron	novel		0.82
UCEC	chr22	31125112	Frame_Shift_Del	novel	*P126Qfs16**	0.53	Exo_endo_phos
UCEC	chr22	31125127	Missense_Mutation	novel	G130C	0.33	Exo_endo_phos
UCEC	chr22	31125644	Missense_Mutation	novel	Q302R	0.22
UCEC	chr22	31125992	Missense_Mutation	novel	K418T	0.33
UCEC	chr22	31127906	Intron	NA		0.29
UCEC	chr22	31134096	Missense_Mutation	NA	R900W	0.26
UCEC	chr22	31134284	Silent	novel	P962P	0.36
UCEC	chr22	31125623	Missense_Mutation	novel	P295L	0.45
UCEC	chr22	31125982	Missense_Mutation	novel	P415S	0.09
UCEC	chr22	31133983	Missense_Mutation	novel	D862G	0.42
UCEC	chr22	31133168	Missense_Mutation	NA	A755V	0.26
UCEC	chr22	31134116	Silent	novel	R906R	0.67
UCEC	chr22	31125860	Missense_Mutation	NA	G374V	0.31
UCEC	chr22	31125308	Missense_Mutation	novel	A190V	0.36	Exo_endo_phos
UCEC	chr22	31122954	5'Flank	novel		0.18
UCEC	chr22	31124981	Missense_Mutation	novel	S81Y	0.4	Exo_endo_phos
UCEC	chr22	31125955	Missense_Mutation	novel	L406M	0.15
UCEC	chr22	31126467	Missense_Mutation	rs762781847	G455S	0.33
UCEC	chr22	31125143	Missense_Mutation	rs773974208	P135L	0.34	Exo_endo_phos
UCEC	chr22	31128554	Missense_Mutation	rs375990503	R698Q	0.29
UCEC	chr22	31128481	Missense_Mutation	rs762380312	R674W	0.17
UCEC	chr22	31125721	Missense_Mutation	rs546001465	R328W	0.5
UCEC	chr22	31128204	Intron	novel		0.43
UCEC	chr22	31125058	Missense_Mutation	novel	A107T	0.32	Exo_endo_phos
UCEC	chr22	31125209	Missense_Mutation	rs776093227	P157L	0.43	Exo_endo_phos
UCEC	chr22	31125936	Silent	novel	T399T	0.42
UCEC	chr22	31127114	Intron	novel		0.25
UCEC	chr22	31127434	Silent	rs370529192	A563A	0.45
UCEC	chr22	31127936	Intron	novel		0.25
UCEC	chr22	31125725	Missense_Mutation	novel	P329H	0.4

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BLCA	AMP	0.1618	0.00055806

Survival Analysis

Cancer	P-value	Q-value
THYM	0.018	Kaplan-Meier Survival Analysis
STAD	0.002	Kaplan-Meier Survival Analysis
SARC	0.0088	Kaplan-Meier Survival Analysis
MESO	0.0035	Kaplan-Meier Survival Analysis
HNSC	0.041	Kaplan-Meier Survival Analysis
SKCM	0.02	Kaplan-Meier Survival Analysis
KIRP	0.017	Kaplan-Meier Survival Analysis
PAAD	0.013	Kaplan-Meier Survival Analysis
BLCA	0.0017	Kaplan-Meier Survival Analysis
READ	0.028	Kaplan-Meier Survival Analysis
LIHC	0.00046	Kaplan-Meier Survival Analysis
LGG	0.0037	Kaplan-Meier Survival Analysis
LUAD	0.00011	Kaplan-Meier Survival Analysis
UVM	0.0017	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000185133 (Gene tree)
Gene ID: 27124
Gene Symbol: INPP5J
Alias: INPP5|PIPP|PIB5PA
Full Name: inositol polyphosphate-5-phosphatase J
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 26,962 bases
Position: chr22:31,107,736-31,134,697
Accession: 8956
RBP type: canonical RBP
Summary: INPP5J (Inositol Polyphosphate-5-Phosphatase J) is a Protein Coding gene. Diseases associated with INPP5J include Lowe Oculocerebrorenal Syndrome and Exudative Vitreoretinopathy 1. Among its related pathways are Metabolism and superpathway of inositol phosphate compounds. Gene Ontology (GO) annotations related to this gene include SH3 domain binding and inositol-1,4,5-trisphosphate 5-phosphatase activity. An important paralog of this gene is INPP5K.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000383150	Exo_endo_phos	PF03372.23	2.2e-10	1	1
ENSP00000384596	Exo_endo_phos	PF03372.23	2.2e-10	1	1
ENSP00000384534	Exo_endo_phos	PF03372.23	2.2e-10	1	1
ENSP00000392924	Exo_endo_phos	PF03372.23	4.2e-10	1	1
ENSP00000333262	Exo_endo_phos	PF03372.23	4.8e-10	1	1
ENSP00000479645	Exo_endo_phos	PF03372.23	2.3e-08	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000461241	INPP5J-211	2810	-	-	- (aa)	-	-
ENST00000401755	INPP5J-203	1751	-	ENSP00000384540	371 (aa)	-	B5MBZ3
ENST00000404453	INPP5J-206	1613	-	ENSP00000385343	371 (aa)	-	B5MBZ3
ENST00000620191	INPP5J-213	2306	-	ENSP00000479645	571 (aa)	-	A0A087WVS7
ENST00000331075	INPP5J-201	3347	-	ENSP00000333262	1006 (aa)	-	Q15735
ENST00000405300	INPP5J-207	2515	-	ENSP00000384596	639 (aa)	-	Q15735
ENST00000412277	INPP5J-208	3512	-	ENSP00000392924	939 (aa)	-	B4DF95
ENST00000404390	INPP5J-205	2215	-	ENSP00000384534	638 (aa)	-	Q15735
ENST00000400294	INPP5J-202	2393	XM_011530143	ENSP00000383150	639 (aa)	XP_011528445	Q15735
ENST00000463528	INPP5J-212	526	-	-	- (aa)	-	-
ENST00000412985	INPP5J-209	805	-	ENSP00000401124	144 (aa)	-	C9K0M5
ENST00000402238	INPP5J-204	1564	-	ENSP00000385264	345 (aa)	-	B5MCL8
ENST00000420017	INPP5J-210	558	-	ENSP00000406570	102 (aa)	-	C9J0H5

Gene Model

Click here to download ENSG00000185133's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa00562	Inositol phosphate metabolism	KEGG
hsa01100	Metabolic pathways	KEGG
hsa04070	Phosphatidylinositol signaling system	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000185133	Gastrointestinal Microbiome	5E-8	27723756

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000185133	rs9917541	22	31133057	?	Gut microbiota (beta diversity)	27723756	NR percent increase	0.71	EFO_0007874

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000185133's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000185133	INPP5J	100	70.874	ENSAPOG00000022396	inpp5ja	99	59.161	Acanthochromis_polyacanthus
ENSG00000185133	INPP5J	60	61.017	ENSAPOG00000014146	inpp5jb	96	61.017	Acanthochromis_polyacanthus
ENSG00000185133	INPP5J	100	95.146	ENSAMEG00000007209	INPP5J	100	86.957	Ailuropoda_melanoleuca
ENSG00000185133	INPP5J	100	68.627	ENSACIG00000018686	inpp5ja	100	63.235	Amphilophus_citrinellus
ENSG00000185133	INPP5J	99	73.267	ENSACIG00000001231	inpp5jb	88	60.181	Amphilophus_citrinellus
ENSG00000185133	INPP5J	100	71.845	ENSAOCG00000005452	inpp5ja	96	58.499	Amphiprion_ocellaris
ENSG00000185133	INPP5J	60	61.714	ENSAPEG00000024494	inpp5jb	93	61.299	Amphiprion_percula
ENSG00000185133	INPP5J	100	65.686	ENSATEG00000017009	inpp5ja	100	61.029	Anabas_testudineus
ENSG00000185133	INPP5J	99	70.297	ENSATEG00000011290	inpp5jb	74	61.033	Anabas_testudineus
ENSG00000185133	INPP5J	100	82.353	ENSAPLG00000012501	INPP5J	94	71.363	Anas_platyrhynchos
ENSG00000185133	INPP5J	100	83.333	ENSACAG00000010115	INPP5J	84	69.072	Anolis_carolinensis
ENSG00000185133	INPP5J	100	99.020	ENSANAG00000026483	INPP5J	100	94.737	Aotus_nancymaae
ENSG00000185133	INPP5J	99	70.297	ENSACLG00000024547	inpp5jb	78	60.849	Astatotilapia_calliptera
ENSG00000185133	INPP5J	77	55.654	ENSAMXG00000035124	-	91	55.506	Astyanax_mexicanus
ENSG00000185133	INPP5J	100	64.706	ENSAMXG00000018608	inpp5ja	90	57.283	Astyanax_mexicanus
ENSG00000185133	INPP5J	100	94.175	ENSBTAG00000017023	INPP5J	97	85.134	Bos_taurus
ENSG00000185133	INPP5J	100	99.020	ENSCJAG00000010779	INPP5J	100	94.141	Callithrix_jacchus
ENSG00000185133	INPP5J	100	95.146	ENSCAFG00000012969	INPP5J	100	87.030	Canis_familiaris
ENSG00000185133	INPP5J	100	95.146	ENSCAFG00020001294	INPP5J	100	87.030	Canis_lupus_dingo
ENSG00000185133	INPP5J	100	93.204	ENSCHIG00000023367	INPP5J	100	85.934	Capra_hircus
ENSG00000185133	INPP5J	100	98.039	ENSTSYG00000028578	INPP5J	100	89.583	Carlito_syrichta
ENSG00000185133	INPP5J	100	96.078	ENSCAPG00000008537	INPP5J	93	85.714	Cavia_aperea
ENSG00000185133	INPP5J	100	96.078	ENSCPOG00000012375	INPP5J	100	82.185	Cavia_porcellus
ENSG00000185133	INPP5J	100	99.020	ENSCCAG00000031908	INPP5J	100	93.942	Cebus_capucinus
ENSG00000185133	INPP5J	100	98.285	ENSCATG00000044969	INPP5J	100	96.226	Cercocebus_atys
ENSG00000185133	INPP5J	100	96.078	ENSCLAG00000008189	INPP5J	100	82.846	Chinchilla_lanigera
ENSG00000185133	INPP5J	100	98.456	ENSCSAG00000008805	INPP5J	100	96.326	Chlorocebus_sabaeus
ENSG00000185133	INPP5J	100	85.294	ENSCPBG00000007417	INPP5J	60	66.724	Chrysemys_picta_bellii
ENSG00000185133	INPP5J	100	98.628	ENSCANG00000029374	INPP5J	100	96.226	Colobus_angolensis_palliatus
ENSG00000185133	INPP5J	100	96.078	ENSCGRG00001022460	Inpp5j	100	84.508	Cricetulus_griseus_chok1gshd
ENSG00000185133	INPP5J	100	96.078	ENSCGRG00000007203	Inpp5j	100	84.508	Cricetulus_griseus_crigri
ENSG00000185133	INPP5J	100	68.932	ENSCSEG00000001743	inpp5ja	91	54.563	Cynoglossus_semilaevis
ENSG00000185133	INPP5J	100	65.686	ENSCVAG00000006319	inpp5ja	100	60.539	Cyprinodon_variegatus
ENSG00000185133	INPP5J	99	69.307	ENSCVAG00000022654	inpp5jb	79	60.993	Cyprinodon_variegatus
ENSG00000185133	INPP5J	100	69.608	ENSDARG00000078542	inpp5ja	100	63.235	Danio_rerio
ENSG00000185133	INPP5J	100	68.627	ENSDARG00000093359	inpp5jb	76	61.982	Danio_rerio
ENSG00000185133	INPP5J	100	95.098	ENSDNOG00000047201	INPP5J	100	85.802	Dasypus_novemcinctus
ENSG00000185133	INPP5J	100	94.118	ENSETEG00000015676	INPP5J	67	87.786	Echinops_telfairi
ENSG00000185133	INPP5J	100	93.162	ENSEASG00005010404	INPP5J	94	90.155	Equus_asinus_asinus
ENSG00000185133	INPP5J	100	93.151	ENSECAG00000006664	INPP5J	97	87.500	Equus_caballus
ENSG00000185133	INPP5J	100	71.569	ENSELUG00000019615	inpp5ja	87	60.952	Esox_lucius
ENSG00000185133	INPP5J	100	71.569	ENSELUG00000014418	inpp5jb	91	62.736	Esox_lucius
ENSG00000185133	INPP5J	100	82.353	ENSFALG00000006819	INPP5J	81	74.178	Ficedula_albicollis
ENSG00000185133	INPP5J	100	96.078	ENSFDAG00000011459	INPP5J	100	81.546	Fukomys_damarensis
ENSG00000185133	INPP5J	100	67.961	ENSFHEG00000001522	inpp5ja	86	53.846	Fundulus_heteroclitus
ENSG00000185133	INPP5J	99	70.297	ENSFHEG00000017114	inpp5jb	93	61.240	Fundulus_heteroclitus
ENSG00000185133	INPP5J	100	71.845	ENSGMOG00000010250	inpp5ja	99	62.264	Gadus_morhua
ENSG00000185133	INPP5J	100	74.510	ENSGMOG00000012173	inpp5jb	100	64.524	Gadus_morhua
ENSG00000185133	INPP5J	100	84.314	ENSGALG00000054099	-	73	79.000	Gallus_gallus
ENSG00000185133	INPP5J	99	71.287	ENSGAFG00000018442	inpp5jb	92	56.389	Gambusia_affinis
ENSG00000185133	INPP5J	100	67.647	ENSGAFG00000008160	inpp5ja	100	60.244	Gambusia_affinis
ENSG00000185133	INPP5J	100	68.932	ENSGACG00000017154	inpp5ja	93	60.280	Gasterosteus_aculeatus
ENSG00000185133	INPP5J	99	71.287	ENSGACG00000008367	inpp5jb	96	62.529	Gasterosteus_aculeatus
ENSG00000185133	INPP5J	100	100.000	ENSGGOG00000002644	INPP5J	100	98.617	Gorilla_gorilla
ENSG00000185133	INPP5J	100	67.647	ENSHBUG00000021461	inpp5ja	100	62.255	Haplochromis_burtoni
ENSG00000185133	INPP5J	100	98.039	ENSHGLG00000006736	INPP5J	100	84.127	Heterocephalus_glaber_female
ENSG00000185133	INPP5J	100	98.039	ENSHGLG00100004490	INPP5J	100	84.722	Heterocephalus_glaber_male
ENSG00000185133	INPP5J	100	65.385	ENSHCOG00000009490	inpp5ja	99	61.538	Hippocampus_comes
ENSG00000185133	INPP5J	99	72.277	ENSHCOG00000000342	inpp5jb	72	62.322	Hippocampus_comes
ENSG00000185133	INPP5J	89	64.835	ENSIPUG00000024179	inpp5ja	93	54.545	Ictalurus_punctatus
ENSG00000185133	INPP5J	100	68.932	ENSIPUG00000020611	inpp5jb	73	60.606	Ictalurus_punctatus
ENSG00000185133	INPP5J	100	97.059	ENSSTOG00000002241	INPP5J	100	85.094	Ictidomys_tridecemlineatus
ENSG00000185133	INPP5J	100	95.098	ENSJJAG00000013285	Inpp5j	100	84.211	Jaculus_jaculus
ENSG00000185133	INPP5J	100	71.154	ENSKMAG00000009393	inpp5ja	88	58.391	Kryptolebias_marmoratus
ENSG00000185133	INPP5J	99	70.297	ENSKMAG00000018294	inpp5jb	78	61.939	Kryptolebias_marmoratus
ENSG00000185133	INPP5J	100	67.961	ENSLBEG00000022361	inpp5ja	97	56.941	Labrus_bergylta
ENSG00000185133	INPP5J	100	69.608	ENSLBEG00000013694	inpp5jb	92	59.670	Labrus_bergylta
ENSG00000185133	INPP5J	100	75.490	ENSLACG00000018176	INPP5J	76	67.451	Latimeria_chalumnae
ENSG00000185133	INPP5J	100	74.510	ENSLOCG00000007855	inpp5ja	81	63.458	Lepisosteus_oculatus
ENSG00000185133	INPP5J	100	98.039	ENSLAFG00000012529	INPP5J	100	85.375	Loxodonta_africana
ENSG00000185133	INPP5J	100	98.799	ENSMFAG00000032773	INPP5J	100	96.425	Macaca_fascicularis
ENSG00000185133	INPP5J	100	98.799	ENSMMUG00000022395	INPP5J	100	96.425	Macaca_mulatta
ENSG00000185133	INPP5J	100	98.599	ENSMNEG00000005244	INPP5J	100	95.957	Macaca_nemestrina
ENSG00000185133	INPP5J	100	98.456	ENSMLEG00000034838	INPP5J	100	95.929	Mandrillus_leucophaeus
ENSG00000185133	INPP5J	99	72.277	ENSMAMG00000016963	inpp5jb	94	63.357	Mastacembelus_armatus
ENSG00000185133	INPP5J	100	67.647	ENSMAMG00000010239	inpp5ja	100	62.439	Mastacembelus_armatus
ENSG00000185133	INPP5J	100	67.647	ENSMZEG00005018143	inpp5ja	100	62.500	Maylandia_zebra
ENSG00000185133	INPP5J	99	70.297	ENSMZEG00005000556	inpp5jb	78	60.849	Maylandia_zebra
ENSG00000185133	INPP5J	100	83.333	ENSMGAG00000009309	INPP5J	96	73.412	Meleagris_gallopavo
ENSG00000185133	INPP5J	100	97.059	ENSMAUG00000013975	Inpp5j	100	84.226	Mesocricetus_auratus
ENSG00000185133	INPP5J	100	97.059	ENSMICG00000008559	INPP5J	100	89.573	Microcebus_murinus
ENSG00000185133	INPP5J	100	97.059	ENSMOCG00000016640	Inpp5j	100	83.449	Microtus_ochrogaster
ENSG00000185133	INPP5J	100	66.019	ENSMMOG00000008021	inpp5ja	90	55.598	Mola_mola
ENSG00000185133	INPP5J	99	70.297	ENSMMOG00000017184	inpp5jb	80	61.466	Mola_mola
ENSG00000185133	INPP5J	100	66.667	ENSMALG00000017345	inpp5ja	100	62.010	Monopterus_albus
ENSG00000185133	INPP5J	99	70.297	ENSMALG00000012659	inpp5jb	78	61.466	Monopterus_albus
ENSG00000185133	INPP5J	100	95.098	MGP_CAROLIEiJ_G0016012	Inpp5j	100	81.764	Mus_caroli
ENSG00000185133	INPP5J	100	95.098	ENSMUSG00000034570	Inpp5j	100	81.944	Mus_musculus
ENSG00000185133	INPP5J	100	97.059	MGP_PahariEiJ_G0016879	Inpp5j	100	82.242	Mus_pahari
ENSG00000185133	INPP5J	100	95.098	MGP_SPRETEiJ_G0016851	-	100	81.944	Mus_spretus
ENSG00000185133	INPP5J	100	95.146	ENSMPUG00000012832	INPP5J	78	84.442	Mustela_putorius_furo
ENSG00000185133	INPP5J	100	93.204	ENSMLUG00000009439	INPP5J	100	83.383	Myotis_lucifugus
ENSG00000185133	INPP5J	100	97.059	ENSNGAG00000012771	Inpp5j	100	85.119	Nannospalax_galili
ENSG00000185133	INPP5J	100	67.647	ENSNBRG00000001367	inpp5ja	100	62.500	Neolamprologus_brichardi
ENSG00000185133	INPP5J	99	73.267	ENSNBRG00000007700	inpp5jb	91	61.838	Neolamprologus_brichardi
ENSG00000185133	INPP5J	100	100.000	ENSNLEG00000004208	INPP5J	100	97.418	Nomascus_leucogenys
ENSG00000185133	INPP5J	100	97.059	ENSODEG00000003778	INPP5J	100	84.387	Octodon_degus
ENSG00000185133	INPP5J	99	73.267	ENSONIG00000013324	inpp5jb	69	59.016	Oreochromis_niloticus
ENSG00000185133	INPP5J	100	69.903	ENSONIG00000003553	inpp5ja	68	54.741	Oreochromis_niloticus
ENSG00000185133	INPP5J	100	85.294	ENSOANG00000000230	INPP5J	96	64.238	Ornithorhynchus_anatinus
ENSG00000185133	INPP5J	100	93.531	ENSOCUG00000000981	INPP5J	100	80.495	Oryctolagus_cuniculus
ENSG00000185133	INPP5J	100	64.706	ENSORLG00000009212	inpp5ja	100	62.010	Oryzias_latipes
ENSG00000185133	INPP5J	99	72.277	ENSORLG00000006273	inpp5jb	97	54.779	Oryzias_latipes
ENSG00000185133	INPP5J	100	64.706	ENSORLG00020015728	inpp5ja	100	61.520	Oryzias_latipes_hni
ENSG00000185133	INPP5J	99	72.277	ENSORLG00020016735	inpp5jb	92	61.033	Oryzias_latipes_hni
ENSG00000185133	INPP5J	99	72.277	ENSORLG00015005100	inpp5jb	92	59.294	Oryzias_latipes_hsok
ENSG00000185133	INPP5J	99	68.317	ENSOMEG00000001787	inpp5jb	77	60.260	Oryzias_melastigma
ENSG00000185133	INPP5J	100	65.686	ENSOMEG00000001846	inpp5ja	100	61.707	Oryzias_melastigma
ENSG00000185133	INPP5J	100	97.059	ENSOGAG00000014553	INPP5J	100	88.183	Otolemur_garnettii
ENSG00000185133	INPP5J	99	80.902	ENSOARG00000009403	INPP5J	99	77.375	Ovis_aries
ENSG00000185133	INPP5J	100	100.000	ENSPPAG00000038214	INPP5J	100	98.908	Pan_paniscus
ENSG00000185133	INPP5J	100	94.175	ENSPPRG00000004336	INPP5J	100	86.806	Panthera_pardus
ENSG00000185133	INPP5J	100	94.175	ENSPTIG00000021441	INPP5J	100	86.905	Panthera_tigris_altaica
ENSG00000185133	INPP5J	100	100.000	ENSPTRG00000014262	INPP5J	100	99.530	Pan_troglodytes
ENSG00000185133	INPP5J	100	98.628	ENSPANG00000018617	INPP5J	100	96.326	Papio_anubis
ENSG00000185133	INPP5J	100	73.529	ENSPKIG00000017651	inpp5jb	81	59.205	Paramormyrops_kingsleyae
ENSG00000185133	INPP5J	100	84.314	ENSPSIG00000008589	-	99	79.832	Pelodiscus_sinensis
ENSG00000185133	INPP5J	60	59.078	ENSPMGG00000017183	-	82	64.664	Periophthalmus_magnuspinnatus
ENSG00000185133	INPP5J	100	62.745	ENSPMGG00000008702	inpp5ja	100	57.108	Periophthalmus_magnuspinnatus
ENSG00000185133	INPP5J	100	96.078	ENSPEMG00000014450	Inpp5j	100	85.277	Peromyscus_maniculatus_bairdii
ENSG00000185133	INPP5J	100	90.196	ENSPCIG00000024523	-	92	82.682	Phascolarctos_cinereus
ENSG00000185133	INPP5J	99	71.287	ENSPFOG00000010595	inpp5jb	56	57.829	Poecilia_formosa
ENSG00000185133	INPP5J	100	69.903	ENSPFOG00000019739	inpp5ja	72	54.064	Poecilia_formosa
ENSG00000185133	INPP5J	100	67.647	ENSPLAG00000010949	inpp5ja	100	60.244	Poecilia_latipinna
ENSG00000185133	INPP5J	99	71.287	ENSPLAG00000008480	inpp5jb	91	58.508	Poecilia_latipinna
ENSG00000185133	INPP5J	74	74.667	ENSPMEG00000009851	inpp5jb	93	60.000	Poecilia_mexicana
ENSG00000185133	INPP5J	100	67.647	ENSPMEG00000013921	inpp5ja	100	60.732	Poecilia_mexicana
ENSG00000185133	INPP5J	68	72.464	ENSPREG00000010611	inpp5ja	94	53.125	Poecilia_reticulata
ENSG00000185133	INPP5J	99	70.297	ENSPREG00000021447	inpp5jb	94	55.556	Poecilia_reticulata
ENSG00000185133	INPP5J	100	99.485	ENSPPYG00000011727	INPP5J	100	98.213	Pongo_abelii
ENSG00000185133	INPP5J	100	93.137	ENSPCAG00000006562	INPP5J	58	92.281	Procavia_capensis
ENSG00000185133	INPP5J	100	99.020	ENSPCOG00000023615	INPP5J	100	90.319	Propithecus_coquereli
ENSG00000185133	INPP5J	100	94.175	ENSPVAG00000001739	INPP5J	100	84.044	Pteropus_vampyrus
ENSG00000185133	INPP5J	99	70.297	ENSPNYG00000014708	inpp5jb	78	60.849	Pundamilia_nyererei
ENSG00000185133	INPP5J	100	67.647	ENSPNYG00000010869	inpp5ja	100	62.500	Pundamilia_nyererei
ENSG00000185133	INPP5J	100	66.667	ENSPNAG00000009242	inpp5ja	90	57.864	Pygocentrus_nattereri
ENSG00000185133	INPP5J	74	76.000	ENSPNAG00000018716	inpp5jb	69	63.542	Pygocentrus_nattereri
ENSG00000185133	INPP5J	100	97.059	ENSRNOG00000019361	Inpp5j	100	83.532	Rattus_norvegicus
ENSG00000185133	INPP5J	100	98.276	ENSRBIG00000037708	INPP5J	100	98.285	Rhinopithecus_bieti
ENSG00000185133	INPP5J	100	98.285	ENSRROG00000032322	INPP5J	100	95.631	Rhinopithecus_roxellana
ENSG00000185133	INPP5J	100	98.039	ENSSBOG00000022773	INPP5J	100	96.252	Saimiri_boliviensis_boliviensis
ENSG00000185133	INPP5J	100	88.235	ENSSHAG00000002057	-	79	78.395	Sarcophilus_harrisii
ENSG00000185133	INPP5J	100	71.569	ENSSFOG00015001597	inpp5jb	94	60.284	Scleropages_formosus
ENSG00000185133	INPP5J	100	65.686	ENSSFOG00015023011	inpp5ja	99	55.846	Scleropages_formosus
ENSG00000185133	INPP5J	100	65.686	ENSSMAG00000020448	inpp5ja	100	61.520	Scophthalmus_maximus
ENSG00000185133	INPP5J	61	64.516	ENSSMAG00000016360	inpp5jb	72	53.428	Scophthalmus_maximus
ENSG00000185133	INPP5J	100	67.647	ENSSDUG00000017189	inpp5ja	100	61.408	Seriola_dumerili
ENSG00000185133	INPP5J	69	71.429	ENSSDUG00000020027	inpp5jb	100	60.519	Seriola_dumerili
ENSG00000185133	INPP5J	99	69.307	ENSSLDG00000017063	inpp5jb	97	59.276	Seriola_lalandi_dorsalis
ENSG00000185133	INPP5J	100	67.647	ENSSLDG00000016645	inpp5ja	100	61.707	Seriola_lalandi_dorsalis
ENSG00000185133	INPP5J	100	70.874	ENSSPAG00000021608	inpp5ja	60	57.524	Stegastes_partitus
ENSG00000185133	INPP5J	99	70.297	ENSSPAG00000023452	inpp5jb	95	57.273	Stegastes_partitus
ENSG00000185133	INPP5J	100	92.466	ENSSSCG00000030345	INPP5J	100	85.233	Sus_scrofa
ENSG00000185133	INPP5J	100	82.353	ENSTGUG00000010717	INPP5J	100	73.621	Taeniopygia_guttata
ENSG00000185133	INPP5J	100	65.049	ENSTRUG00000020386	inpp5ja	100	61.520	Takifugu_rubripes
ENSG00000185133	INPP5J	99	71.287	ENSTRUG00000011059	inpp5jb	96	61.916	Takifugu_rubripes
ENSG00000185133	INPP5J	99	71.287	ENSTNIG00000015839	inpp5jb	95	63.962	Tetraodon_nigroviridis
ENSG00000185133	INPP5J	100	67.961	ENSTNIG00000009110	inpp5ja	100	60.900	Tetraodon_nigroviridis
ENSG00000185133	INPP5J	100	96.117	ENSUAMG00000010027	INPP5J	100	93.825	Ursus_americanus
ENSG00000185133	INPP5J	100	96.117	ENSUMAG00000016037	INPP5J	100	93.139	Ursus_maritimus
ENSG00000185133	INPP5J	100	95.146	ENSVVUG00000002420	INPP5J	100	86.436	Vulpes_vulpes
ENSG00000185133	INPP5J	100	74.510	ENSXETG00000016154	inpp5j	71	64.637	Xenopus_tropicalis
ENSG00000185133	INPP5J	99	66.337	ENSXCOG00000017414	inpp5jb	83	53.239	Xiphophorus_couchianus
ENSG00000185133	INPP5J	100	67.647	ENSXMAG00000027563	inpp5ja	100	60.000	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001726	ruffle	21873635.	IBA	Component
GO:0001726	ruffle	12536145.	IDA	Component
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	21873635.	IBA	Function
GO:0004445	inositol-polyphosphate 5-phosphatase activity	-	IEA	Function
GO:0005515	protein binding	25416956.	IPI	Function
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005737	cytoplasm	12536145.	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0005886	plasma membrane	21873635.	IBA	Component
GO:0006661	phosphatidylinositol biosynthetic process	-	TAS	Process
GO:0010977	negative regulation of neuron projection development	-	IEA	Process
GO:0017124	SH3 domain binding	-	IEA	Function
GO:0030426	growth cone	-	IEA	Component
GO:0031115	negative regulation of microtubule polymerization	-	IEA	Process
GO:0033137	negative regulation of peptidyl-serine phosphorylation	21873635.	IBA	Process
GO:0034485	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity	21873635.	IBA	Function
GO:0043198	dendritic shaft	-	IEA	Component
GO:0043647	inositol phosphate metabolic process	-	TAS	Process
GO:0046855	inositol phosphate dephosphorylation	21873635.	IBA	Process
GO:0046856	phosphatidylinositol dephosphorylation	21873635.	IBA	Process
GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity	-	IEA	Function
GO:0052659	inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity	-	IEA	Function

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.