EuRBPDB

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TCGA tumor abbreviations
  • ACCAdrenocortical carcinoma
  • BLCABladder Urothelial Carcinoma
  • BRCABreast invasive carcinoma
  • CESCCervical squamous cell carcinoma and endocervical adenocarcinoma
  • CHOLCholangio carcinoma
  • COADColon adenocarcinoma
  • DLBCLymphoid Neoplasm Diffuse Large B-cell Lymphoma
  • ESCAEsophageal carcinoma
  • GBMGlioblastoma multiforme
  • HNSCHead and Neck squamous cell carcinoma
  • KICHKidney Chromophobe
  • KIRCKidney renal clear cell carcinoma
  • KIRPKidney renal papillary cell carcinoma
  • LAMLAcute Myeloid Leukemia
  • LGGBrain Lower Grade Glioma
  • LIHCLiver hepatocellular carcinoma
  • LUADLung adenocarcinoma
  • LUSCLung squamous cell carcinoma
  • MESOMesothelioma
  • OVOvarian serous cystadenocarcinoma
  • PAADPancreatic adenocarcinoma
  • PCPGPheochromocytoma and Paraganglioma
  • PRADProstate adenocarcinoma
  • READRectum adenocarcinoma
  • SARCSarcoma
  • SKCMSkin Cutaneous Melanoma
  • STADStomach adenocarcinoma
  • TGCTThyroid carcinoma
  • THCAThyroid carcinoma
  • THYMThymoma
  • UCECUterine Corpus Endometrial Carcinoma
  • UCSUterine Carcinosarcoma
  • UVMUveal Melanoma

Note: Click here to get the extension of tumor abbreviations.


  • Cancer Related Information
  • Basic Information

Differential Expression

Expression in 33 cancers

Mutations
CancerChrPosition Mutation TypedbSNPProtein-change Allele FreqRBD
BLCAchr1781670222Splice_Regionnovel0.66
BRCAchr1781672618Missense_MutationNAY262H0.17
BRCAchr1781667780Missense_MutationNAE62D0.48
CESCchr17816667425'UTRnovel0.42
CESCchr17816667425'UTRnovel0.47
COADchr17816728513'UTRnovel0.35
COADchr1781672519Missense_Mutationrs371084134R229W0.42
COADchr1781671758Missense_MutationnovelR171Q0.21
COADchr1781671804SilentNAR186R0.21
COADchr1781667772Missense_MutationNAE60K0.19
COADchr1781670294Missense_MutationnovelK113T0.12
COADchr1781672653Silentrs377260728H273H0.49
ESCAchr1781672141Missense_Mutationrs201656915V216I0.17
ESCAchr1781666862SilentnovelL32L0.33
GBMchr1781670354Missense_MutationnovelA133D0.24
KIRCchr1781672101SilentnovelV202V0.23
LGGchr1781671794Missense_Mutationrs79563828A183V0.29
LIHCchr1781672155Splice_Regionrs373550389Q220Q0.55
LIHCchr1781671772Nonsense_MutationNAR176*0.2
LIHCchr17816667535'UTRnovel0.45
LUADchr1781671773Missense_Mutationrs748766769R176L0.08
LUSCchr1781672083SilentnovelV196V0.36
LUSCchr1781667844Missense_MutationNAK84E0.5
OVchr1781670376SilentnovelS140S0.14
PAADchr1781670453Missense_Mutationrs779033426A166V0.19
SKCMchr1781667726Splice_Regionnovel0.31
SKCMchr1781670289Silentrs769022420V111V0.28
SKCMchr1781670290Missense_MutationnovelP112T0.28
SKCMchr17816667285'UTRrs7604598650.51
SKCMchr1781670454Splice_Siters201831605X166_splice0.61
SKCMchr1781672131SilentNAP212P0.19
STADchr1781672108Frame_Shift_DelnovelP206Qfs*30.39
UCECchr1781670444Frame_Shift_InsNAA166Sfs*90.3
UCECchr1781672536Silentrs749149362P234P0.47
UCECchr1781670445Frame_Shift_DelNAA166Rfs*70.44
UCECchr1781667836Missense_MutationnovelI81S0.06
UCECchr1781670406SilentnovelV150V0.38
UCECchr17816729203'UTRnovel0.67
UCECchr1781671823Nonsense_Mutationrs752861811R193*0.38
UCECchr1781672560Silentrs75933860T242T0.36
UCECchr1781671765Frame_Shift_InsNAV175Sfs*260.4
UCECchr1781672605SilentNAR257R0.31
UCECchr1781667829Missense_MutationnovelN79D0.38
UCECchr1781670278Missense_MutationnovelD108N0.67
UCECchr1781670444Frame_Shift_InsNAA166Sfs*90.37
UCECchr1781667735Missense_MutationnovelE47D0.07

Copy Number Variations (CNVs)
CancerTypeFreq Q-value
BLCAAMP0.38970.00012456
CESCDEL0.10510.00067839
KIRPAMP0.67010.14801
LGGAMP0.07211.52e-05
SARCAMP0.20230.032181
SKCMAMP0.28347.0388e-08
THCADEL0.0020.221
UVMAMP0.16250.054583

Survival Analysis
CancerP-value Q-value
MESO0.014

Kaplan-Meier Survival Analysis

ACC0.0013

Kaplan-Meier Survival Analysis

SKCM0.023

Kaplan-Meier Survival Analysis

LUSC0.036

Kaplan-Meier Survival Analysis

PAAD0.027

Kaplan-Meier Survival Analysis

LAML0.00053

Kaplan-Meier Survival Analysis

UCEC0.047

Kaplan-Meier Survival Analysis

GBM0.037

Kaplan-Meier Survival Analysis

LIHC0.0001

Kaplan-Meier Survival Analysis

LGG0.00011

Kaplan-Meier Survival Analysis

LUAD0.0035

Kaplan-Meier Survival Analysis

UVM0.025

Kaplan-Meier Survival Analysis

OV0.041

Kaplan-Meier Survival Analysis

  • Description
  • RBPome
  • Expression
  • Transcripts
  • Gene Model
  • PPI
  • Orthologs
  • Gene Ontology
Description
Ensembl ID
ENSG00000185298 (Gene tree)
Gene ID
339230
Gene Symbol
CCDC137
Alias
MGC16597
Full Name
coiled-coil domain containing 137
Gene Type
protein_coding
Species
Homo_sapiens
Status
putative
Strand
Plus strand
Length
7,544 bases
Position
chr17:81,666,364-81,673,907
Accession
33451
RBP type
non-canonical RBP
Summary
(Coiled-Coil Domain Containing 137) is a Protein Coding gene.
RNA binding proteome (RBPome)
PIDTitleMethod TimeAuthorDoi
22681889The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts4SURIC & HEK2932012 MayBaltz AGDOI: 10.1016/j.molcel.2012.05.021
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & HEK2932019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & HEK2932018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
29431736Capturing the interactome of newly transcribed RNAPolyT-RICK & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
29431736Capturing the interactome of newly transcribed RNARIC & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
22658674Insights into RNA biology from an atlas of mammalian mRNA-binding proteinsRIC & Hela2012 May 31Castello ADOI: 10.1016/j.cell.2012.04.031
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & Hela2018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & MCF10A2019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & MCF72018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & U2OS2019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
Expression
Transcripts
Transcript IDNameLengthRefSeq ID Protein IDLengthRefSeq IDUniportKB ID
ENST00000329214CCDC137-2012468XM_011524738ENSP00000329360289 (aa)XP_011523040Q6PK04
ENST00000575223CCDC137-2061888-ENSP00000458884289 (aa)-Q6PK04
ENST00000572531CCDC137-203265--- (aa)--
ENST00000574200CCDC137-205437-ENSP0000046120744 (aa)-I3L4F6
ENST00000571916CCDC137-202708-ENSP0000046026161 (aa)-I3L385
ENST00000574107CCDC137-204890-ENSP00000458350292 (aa)-I3L0U5
Gene Model
Click here to download ENSG00000185298's gene model file
Protein-Protein Interaction (PPI)

Clik here to download ENSG00000185298's network

* RBP PPI network refers to all genes directly bind to RBP
Orthologs identified by RBPome
Ensembl IDGene SymbolCoverageIdentiy OrthologGene SymbolCoverageIdentiy Species
ENSG00000185298CCDC1378777.358ENSMUSG00000049957Ccdc1379372.894Mus_musculus
Gene Ontology
Go IDGo_termPubmedIDEvidenceCategory
GO:0001650fibrillar center-IDAComponent
GO:0003723RNA binding22658674.22681889.HDAFunction
GO:0005515protein binding21044950.IPIFunction
GO:0005694chromosome20813266.IDAComponent
GO:0005730nucleolus-IDAComponent
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