EuRBPDB

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TCGA tumor abbreviations
  • ACCAdrenocortical carcinoma
  • BLCABladder Urothelial Carcinoma
  • BRCABreast invasive carcinoma
  • CESCCervical squamous cell carcinoma and endocervical adenocarcinoma
  • CHOLCholangio carcinoma
  • COADColon adenocarcinoma
  • DLBCLymphoid Neoplasm Diffuse Large B-cell Lymphoma
  • ESCAEsophageal carcinoma
  • GBMGlioblastoma multiforme
  • HNSCHead and Neck squamous cell carcinoma
  • KICHKidney Chromophobe
  • KIRCKidney renal clear cell carcinoma
  • KIRPKidney renal papillary cell carcinoma
  • LAMLAcute Myeloid Leukemia
  • LGGBrain Lower Grade Glioma
  • LIHCLiver hepatocellular carcinoma
  • LUADLung adenocarcinoma
  • LUSCLung squamous cell carcinoma
  • MESOMesothelioma
  • OVOvarian serous cystadenocarcinoma
  • PAADPancreatic adenocarcinoma
  • PCPGPheochromocytoma and Paraganglioma
  • PRADProstate adenocarcinoma
  • READRectum adenocarcinoma
  • SARCSarcoma
  • SKCMSkin Cutaneous Melanoma
  • STADStomach adenocarcinoma
  • TGCTThyroid carcinoma
  • THCAThyroid carcinoma
  • THYMThymoma
  • UCECUterine Corpus Endometrial Carcinoma
  • UCSUterine Carcinosarcoma
  • UVMUveal Melanoma

Note: Click here to get the extension of tumor abbreviations.


  • Cancer Related Information
  • Basic Information

Differential Expression

Expression in 33 cancers

Mutations
CancerChrPosition Mutation TypedbSNPProtein-change Allele FreqRBD
ACCchr1468789825Missense_MutationnovelT242S0.15
BLCAchr1468789856SilentnovelL232L0.34
BLCAchr14687929525'UTRnovel0.28
BLCAchr14687930445'UTRnovel0.33
BLCAchr1468790451Frame_Shift_InsNAC34Lfs*410.98
BLCAchr1468789653SilentnovelL299L0.32
BLCAchr1468790275Nonsense_MutationnovelS92*0.29
BLCAchr1468790399Missense_MutationnovelR51W0.29
BLCAchr1468789956Frame_Shift_InsnovelQ199Pfs*30.53
BLCAchr1468789670Frame_Shift_InsnovelS294Qfs*450.26
BLCAchr1468789913Frame_Shift_InsnovelT213Hfs*240.19
BLCAchr1468790031Nonsense_MutationnovelC173*0.92zf-CCCH
BLCAchr1468792884Nonsense_MutationnovelK19*0.48
BLCAchr14687963435'Flanknovel0.35
BLCAchr1468789738Frame_Shift_DelNAG271Vfs*360.5
BLCAchr1468790119Frame_Shift_DelnovelF137Sfs*40.3
BLCAchr1468790044Missense_MutationnovelY169C0.35zf-CCCH
BLCAchr1468789861Frame_Shift_DelnovelP230Lfs*30.42
BLCAchr1468792889Frame_Shift_DelnovelF11Yfs*630.31
BLCAchr1468790389Nonsense_MutationNAS54*0.31
BLCAchr1468790266Missense_MutationnovelG95V0.45
BLCAchr14687960895'FlankNA0.35
BLCAchr1468789965Frame_Shift_InsnovelP196Sfs*60.73
BLCAchr1468790067Frame_Shift_InsnovelH162Pfs*190.21zf-CCCH
BLCAchr1468790318Frame_Shift_InsnovelA78Pfs*30.21
BLCAchr1468790424Frame_Shift_InsnovelT43Hfs*320.15
BLCAchr14687959835'FlankNA0.14
BLCAchr1468790130Frame_Shift_InsnovelI141Hfs*400.5
BLCAchr1468789994Missense_MutationNAA186T0.21
BLCAchr1468789734Frame_Shift_InsnovelS273Lfs*180.17
BLCAchr1468789826Frame_Shift_InsnovelT242Lfs*660.09
BLCAchr1468790209Frame_Shift_InsnovelR114Qfs*120.18
BLCAchr1468789582Frame_Shift_InsnovelN323Tfs*400.26
BLCAchr1468790333Missense_MutationnovelG73S0.42
BLCAchr1468789951Frame_Shift_InsnovelH200Rfs*340.33
BLCAchr14687961765'Flankrs7711025020.18
BLCAchr1468789817Frame_Shift_InsnovelD245Rfs*50.4
BLCAchr14687958405'FlankNA0.49
BLCAchr1468789616Missense_Mutationrs756918933S312R0.23
BLCAchr1468790264Frame_Shift_InsnovelE96Rfs*290.36
BLCAchr1468790291Missense_MutationnovelR87G0.18
BLCAchr14687963295'Flanknovel0.26
BLCAchr1468789806Frame_Shift_Insrs775692081N248Kfs*20.17
BLCAchr1468790061In_Frame_DelnovelH162_T163del0.61zf-CCCH
BLCAchr14687929675'UTRnovel0.56
BRCAchr1468789642Frame_Shift_InsnovelE303Gfs*360.09
BRCAchr1468792894Frame_Shift_DelnovelI10Ffs*640.23
BRCAchr14687952805'Flanknovel0.33
BRCAchr1468790175Frame_Shift_DelnovelY115*0.22
BRCAchr1468789872Frame_Shift_InsnovelT227Afs*110.24
BRCAchr14687930685'UTRnovel0.13
BRCAchr1468790022In_Frame_DelNAI176del0.27zf-CCCH
BRCAchr1468790044Missense_MutationNAY169S0.36zf-CCCH
BRCAchr1468790310Frame_Shift_DelnovelP77Rfs*670.41
BRCAchr1468790207Frame_Shift_InsNAY115Afs*340.79
BRCAchr14687885933'Flanknovel0.05
BRCAchr1468792905Missense_MutationnovelD12N0.08
BRCAchr14687876763'Flanknovel0.5
BRCAchr1468790090Nonsense_MutationNAK154*0.69zf-CCCH
BRCAchr1468790451Frame_Shift_InsNAC34Lfs*410.48
BRCAchr14687929795'UTRnovel0.21
BRCAchr1468790424Frame_Shift_InsnovelT43Hfs*320.26
BRCAchr14687878763'Flanknovel0.15
CESCchr14687886183'UTRnovel0.49
CESCchr14687959775'FlankNA0.26
CESCchr1468789597Missense_MutationNAS318F0.1
CESCchr1468790058SilentNAI164I0.09
CESCchr14687886173'UTRnovel0.37
CESCchr14687884543'Flanknovel0.41
CESCchr14687958315'Flanknovel0.52
CESCchr14687964365'Flanknovel0.45
CESCchr1468790074Missense_MutationnovelR159H0.44zf-CCCH
CESCchr1468790258Missense_MutationnovelL98M0.35
CESCchr1468789651Nonsense_MutationnovelS300*0.36
CESCchr14687930625'UTRnovel0.4
CESCchr14687958005'Flanknovel0.48
CESCchr14687960895'FlankNA0.53
CESCchr1468792924SilentNAL5L0.25
CESCchr1468789123Intronnovel0.22
CESCchr14687878763'Flanknovel0.33
CESCchr14687884273'Flanknovel0.25
CESCchr14687949585'Flanknovel0.31
CESCchr14687929835'UTRnovel0.49
CESCchr14687886183'UTRnovel0.27
CESCchr14687956445'Flanknovel0.46
CESCchr14687952175'Flanknovel0.27
CHOLchr14687952595'Flanknovel0.26
COADchr1468789456Intronnovel0.35
COADchr1468790069Missense_MutationNAF161V0.26zf-CCCH
COADchr14687956725'Flanknovel0.29
COADchr1468790290Missense_MutationNAR87Q0.3
COADchr1468789738Frame_Shift_DelNAG271Vfs*360.32
COADchr1468790094SilentNAK152K0.56
COADchr14687962385'Flanknovel0.25
COADchr1468789708Missense_MutationNAP281L0.14
COADchr1468789671Frame_Shift_DelNAS294Afs*130.33
COADchr1468789848Silentrs754764949A234A0.3
COADchr1468790042Missense_MutationNAG170W0.41zf-CCCH
COADchr14687962405'Flanknovel0.3
COADchr1468790186Missense_MutationNAP122S0.28
COADchr1468789687Missense_MutationNAM288T0.23
COADchr1468789297Intronnovel0.8
COADchr1468790021Frame_Shift_DelNAH177Tfs*560.79zf-CCCH
COADchr1468789729Frame_Shift_DelNAP274Rfs*330.26
COADchr14687962405'Flanknovel0.51
DLBCchr1468790198Frame_Shift_DelnovelS113Rfs*70.16
ESCAchr14687962405'Flanknovel0.28
ESCAchr14687930065'UTRnovel0.18
ESCAchr14687886343'UTRnovel0.42
GBMchr1468790344Frame_Shift_InsnovelS69Tfs*170.13
GBMchr1468790237Missense_MutationNAP105S0.3
HNSCchr1468790319SilentnovelP77P0.17
HNSCchr14687962795'Flanknovel0.27
HNSCchr1468790328Frame_Shift_InsnovelP75Afs*500.36
HNSCchr1468789860SilentnovelP230P0.08
HNSCchr1468789816Missense_MutationnovelD245V0.42
HNSCchr1468790409SilentnovelG47G0.28
HNSCchr1468790303Missense_MutationnovelD83H0.32
HNSCchr1468789851Silentrs750342662S233S0.09
KIRCchr1468789460Intronnovel0.17
KIRCchr1468789590Frame_Shift_DelNAL321Wfs*410.05
KIRCchr1468789511Intronnovel0.27
KIRPchr1468790115SilentnovelR145R0.41
KIRPchr1468790045Missense_MutationnovelY169H0.48zf-CCCH
KIRPchr14687929655'UTRnovel0.52
KIRPchr1468789774In_Frame_DelnovelF251_A259del0.2
KIRPchr1468789632SilentnovelL306L0.42
LAMLchr1468789649Missense_MutationnovelD301H0.07
LGGchr1468790050Frame_Shift_InsnovelC167Lfs*140.33zf-CCCH
LGGchr14687957985'Flanknovel0.18
LIHCchr1468789550Frame_Shift_DelnovelS334Pfs*280.07
LIHCchr1468789596SilentnovelS318S0.47
LIHCchr14687957745'Flanknovel0.25
LIHCchr1468789695SilentnovelS285S0.76
LIHCchr14687929685'UTRnovel0.22
LIHCchr1468789718Missense_MutationNAL278I0.57
LIHCchr14687929485'UTRnovel0.39
LIHCchr1468789578SilentnovelS324S0.14
LIHCchr14687957785'Flanknovel0.18
LIHCchr1468790039Missense_MutationnovelP171S0.7zf-CCCH
LUADchr1468790027In_Frame_InsnovelT163_H174dup0.07zf-CCCH
LUADchr1468790067Missense_MutationNAF161L0.41zf-CCCH
LUADchr14687957595'Flanknovel0.53
LUADchr1468789781Nonsense_MutationNAE257*0.06
LUADchr1468790036Missense_MutationNAR172C0.17zf-CCCH
LUADchr1468789742Frame_Shift_InsnovelG270Rfs*210.43
LUADchr1468790273Nonsense_MutationNAE93*0.15
LUADchr14687929655'UTRnovel0.17
LUADchr1468789781Nonsense_MutationNAE257*0.07
LUADchr14687929965'UTRnovel0.29
LUADchr1468789781Missense_MutationNAE257K0.29
LUADchr1468790268SilentNAG94G0.53
LUADchr1468789883Missense_MutationnovelP223S0.22
LUADchr1468789781Missense_MutationNAE257K0.16
LUADchr1468790234Missense_MutationnovelG106W0.22
LUADchr1468789648Missense_MutationNAD301V0.32
LUSCchr1468790402Missense_MutationnovelP50S0.5
LUSCchr14687930675'UTRnovel0.2
LUSCchr14687958535'Flanknovel0.24
LUSCchr1468792906Missense_MutationnovelF11L0.04
LUSCchr1468789817Missense_MutationnovelD245N0.44
LUSCchr1468789919Missense_MutationNAA211S0.12
LUSCchr1468789883Frame_Shift_DelnovelL219Hfs*130.44
LUSCchr1468790009Missense_MutationNAE181Q0.13
LUSCchr1468790061SilentnovelT163T0.3
LUSCchr1468790206Missense_MutationnovelY115C0.3
LUSCchr14687959115'FlankNA0.13
LUSCchr1468789728SilentnovelP274P0.21
LUSCchr1468790134Missense_MutationnovelH139L0.71
LUSCchr14687963035'Flanknovel0.13
OVchr14687881213'Flanknovel0.88
OVchr14687961735'FlankNA0.21
OVchr14687957325'Flanknovel0.36
OVchr1468792909SilentNAI10I0.19
OVchr1468790376Frame_Shift_DelnovelS59Afs*210.36
PRADchr1468790146Missense_MutationNAC135F0.19
PRADchr14687959405'Flanknovel0.36
PRADchr1468789738Frame_Shift_DelNAG271Vfs*360.1
PRADchr1468790003Missense_MutationNAR183G0.49
READchr1468789467Intronnovel0.42
SARCchr14687880593'Flanknovel0.61
SARCchr14687879683'Flanknovel0.54
SARCchr14687881133'Flanknovel0.29
SARCchr1468789671Frame_Shift_DelNAS294Afs*130.36
SKCMchr14687961665'FlankNA0.33
SKCMchr1468789719SilentNAF277F0.25
SKCMchr1468790139SilentNAF137F0.1
SKCMchr14687961655'FlankNA0.3
SKCMchr14687957415'Flanknovel0.5
SKCMchr1468792896Missense_MutationNAE15K0.58
SKCMchr14687930225'UTRnovel0.23
SKCMchr14687962955'Flankrs7708872700.09
SKCMchr1468789824SilentnovelT242T0.27
SKCMchr1468789716Silentrs760082533L278L0.18
SKCMchr1468789716Silentrs760082533L278L0.45
SKCMchr1468790322Silentrs752733615A76A0.3
SKCMchr1468789675Missense_MutationnovelP292L0.33
SKCMchr1468789882Missense_MutationnovelP223L0.49
STADchr14687963945'Flanknovel0.35
STADchr1468790050Frame_Shift_InsnovelC167Lfs*140.56zf-CCCH
STADchr1468789880Frame_Shift_InsnovelT224Hfs*130.49
STADchr1468789738Frame_Shift_DelNAG271Vfs*360.14
STADchr1468790230Frame_Shift_DelnovelG107Afs*410.26
STADchr1468789738Frame_Shift_DelNAG271Vfs*360.15
STADchr1468789738Frame_Shift_DelNAG271Vfs*360.26
STADchr1468789738Frame_Shift_DelNAG271Vfs*360.19
STADchr1468789689SilentnovelH287H0.43
UCECchr14687929595'UTRnovel0.34
UCECchr1468790210Missense_MutationnovelR114C0.23
UCECchr14687887283'UTRnovel0.52
UCECchr1468788836Intronnovel0.11
UCECchr14687887853'UTRnovel0.29
UCECchr1468790014Missense_MutationnovelA179D0.29
UCECchr1468789728Silentrs773937725P274P0.31
UCECchr14687879443'Flanknovel0.44
UCECchr1468789868Missense_MutationnovelP228S0.09
UCECchr14687884923'Flanknovel0.4
UCECchr14687885933'Flanknovel0.5
UCECchr1468790025Missense_MutationnovelF175L0.08zf-CCCH
UCECchr1468790308Frame_Shift_DelNAS81Cfs*670.33
UCECchr14687885933'Flanknovel0.28
UCECchr1468789738Frame_Shift_DelNAG271Vfs*360.28
UCECchr14687883263'Flanknovel0.33
UCECchr14687886183'UTRnovel0.44
UCECchr14687885063'Flanknovel0.28
UCECchr14687886183'UTRnovel0.36
UCECchr1468789074Intronnovel0.37
UCECchr14687886353'UTRnovel0.14
UCECchr14687886183'UTRnovel0.38
UCECchr14687880713'Flanknovel0.33
UCECchr1468790168Missense_MutationnovelA128T0.44
UCECchr1468789368Intronnovel0.23
UCECchr1468790085SilentnovelT155T0.47
UCECchr14687962405'Flanknovel0.46
UCECchr1468790386Missense_MutationnovelV55D0.44
UCECchr1468789738Frame_Shift_DelNAG271Vfs*360.26
UCECchr14687883263'Flanknovel0.82
UCECchr14687878293'Flanknovel0.36
UCECchr1468790145Nonsense_MutationnovelC135*0.32
UCECchr1468789947Missense_MutationnovelS201R0.45
UCECchr14687886173'UTRnovel0.38
UCECchr1468790266Frame_Shift_DelnovelG95Afs*530.19
UCECchr14687950895'Flanknovel0.4
UCECchr1468789738Frame_Shift_DelNAG271Vfs*360.4
UCECchr14687962035'Flanknovel0.46
UCECchr1468789433Intronnovel0.31
UCECchr14687952075'Flanknovel0.17
UCECchr14687929405'UTRnovel0.19
UCECchr1468789671Frame_Shift_DelNAS294Afs*130.08
UCECchr14687879423'Flanknovel0.49
UCECchr14687886253'UTRnovel0.38
UCECchr1468789719SilentNAF277F0.23
UCECchr1468790215Missense_MutationnovelS112F0.38
UCECchr1468790324Missense_MutationnovelA76S0.26
UCECchr14687886223'UTRnovel0.55
UCECchr1468790141Missense_MutationnovelF137L0.48
UCECchr14687879013'Flanknovel0.43
UCECchr14687876883'Flanknovel0.45
UCECchr1468789382Intronnovel0.15
UCECchr14687886973'UTRnovel0.44
UCECchr14687878123'Flanknovel0.43
UCECchr1468789852Missense_MutationnovelS233N0.35
UCSchr1468790329Frame_Shift_DelnovelN65Sfs*60.44
UCSchr1468789579Nonsense_MutationNAS324*0.54

Copy Number Variations (CNVs)
CancerTypeFreq Q-value
ACCDEL0.14440.19769
BLCADEL0.26471.3074e-08
BRCADEL0.27221.4717e-06
CESCDEL0.10510.00086239
CHOLDEL0.55560.00040262
COADDEL0.28820.050084
GBMDEL0.27215.7274e-07
HNSCDEL0.0920.0057325
KIRCDEL0.38070.0074281
KIRPDEL0.16670.085174
LGGDEL0.20471.1681e-13
LIHCDEL0.31358.4799e-08
LUADDEL0.20160.0018747
LUSCAMP0.17560.064655
MESODEL0.40230.088547
OVAMP0.0950.0046435
OVDEL0.46986.0694e-08
PAADDEL0.06520.11332
READDEL0.35760.189
SARCDEL0.28790.0013077
SKCMDEL0.27790.10277
STADDEL0.21320.0031145

Survival Analysis
CancerP-value Q-value
THYM0.0026

Kaplan-Meier Survival Analysis

UCS0.0012

Kaplan-Meier Survival Analysis

KIRP0.0049

Kaplan-Meier Survival Analysis

COAD0.034

Kaplan-Meier Survival Analysis

PAAD0.0037

Kaplan-Meier Survival Analysis

PCPG0.033

Kaplan-Meier Survival Analysis

GBM0.021

Kaplan-Meier Survival Analysis

LIHC0.024

Kaplan-Meier Survival Analysis

LGG0.00034

Kaplan-Meier Survival Analysis

CHOL0.04

Kaplan-Meier Survival Analysis

OV0.0028

Kaplan-Meier Survival Analysis

Drugs

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Eesembl ID



Cell lines and drugs in GSE70138 or GSE92742

  • Description
  • RBDs
  • RBPome
  • Literatures
  • Expression
  • Transcripts
  • Gene Model
  • Pathways
  • Phenotypes
  • GWAS
  • PPI
  • Paralogs
  • Orthologs
  • Gene Ontology
Description
Ensembl ID
ENSG00000185650 (Gene tree)
Gene ID
677
Gene Symbol
ZFP36L1
Alias
RNF162B|Berg36|ERF1|TIS11B|cMG1|BRF1
Full Name
ZFP36 ring finger protein like 1
Gene Type
protein_coding
Species
Homo_sapiens
Status
confidence
Strand
Minus strand
Length
8,599 bases
Position
chr14:68,787,655-68,796,253
Accession
1107
RBP type
canonical RBP
Summary
This gene is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
RNA binding domains(RBDs)
Protein IDDomain Pfam IDE-value Domain number Total number
ENSP00000450600zf-CCCHPF00642.249.2e-2312
ENSP00000450600zf-CCCHPF00642.249.2e-2322
ENSP00000450784zf-CCCHPF00642.241.5e-2212
ENSP00000450784zf-CCCHPF00642.241.5e-2222
ENSP00000337386zf-CCCHPF00642.245.6e-2212
ENSP00000337386zf-CCCHPF00642.245.6e-2222
ENSP00000388402zf-CCCHPF00642.245.6e-2212
ENSP00000388402zf-CCCHPF00642.245.6e-2222
RNA binding proteome (RBPome)
PIDTitleMethod TimeAuthorDoi
29431736Capturing the interactome of newly transcribed RNARIC & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
22658674Insights into RNA biology from an atlas of mammalian mRNA-binding proteinsRIC & Hela2012 May 31Castello ADOI: 10.1016/j.cell.2012.04.031

Literatures on RNA binding capacity
PIDTitleArticle TimeAuthorDoi
16306087Antagonistic functions of tetradecanoyl phorbol acetate-inducible-sequence 11b and HuR in the hormonal regulation of vascular endothelial growth factor messenger ribonucleic acid stability by adrenocorticotropin.Mol Endocrinol2006 AprCherradi N-
23423171Ovarian regulation of neuromedin U and its local actions in the ovary, mediated through neuromedin U receptor 2.Am J Physiol Endocrinol Metab2013 Apr 15Lin TYdoi: 10.1152/ajpendo.00548.2012
30962286AU-rich element-mediated mRNA decay via the butyrate response factor 1 controls cellular levels of polyadenylated replication-dependent histone mRNAs.J Biol Chem2019 May 10Ryu Idoi: 10.1074/jbc.AC118.006766
15226444Chorioallantoic fusion defects and embryonic lethality resulting from disruption of Zfp36L1, a gene encoding a CCCH tandem zinc finger protein of the Tristetraprolin family.Mol Cell Biol2004 JulStumpo DJ-
11796723Members of the tristetraprolin family of tandem CCCH zinc finger proteins exhibit CRM1-dependent nucleocytoplasmic shuttling.J Biol Chem2002 Mar 29Phillips RS-
19801654Von Hippel-Lindau gene product modulates TIS11B expression in renal cell carcinoma: impact on vascular endothelial growth factor expression in hypoxia.J Biol Chem2009 Nov 20Sinha Sdoi: 10.1074/jbc.M109.058065
18419273Biological clocks and the coordination theory of RNA operons and regulons.Cold Spring Harb Symp Quant Biol2007Keene JDdoi: 10.1101/sqb.2007.72.013.
17013884The RNA binding protein Zfp36l1 is required for normal vascularisation and post-transcriptionally regulates VEGF expression.Dev Dyn2006 NovBell SE-
23266986Involvement of XZFP36L1, an RNA-binding protein, in Xenopus neural development.Dongwuxue Yanjiu2012 DecXia YJdoi: 10.3724/SP.J.1141.2012.E05-06E82.
21278925The roles of TTP and BRF proteins in regulated mRNA decay.Wiley Interdiscip Rev RNA2011 Jan-FebSanduja Sdoi: 10.1002/wrna.28.
20622884Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia.Nat Immunol2010 AugHodson DJdoi: 10.1038/ni.1901
25014217Post-transcriptional regulation of BCL2 mRNA by the RNA-binding protein ZFP36L1 in malignant B cells.PLoS One2014 Jul 11Zekavati Adoi: 10.1371/journal.pone.0102625
27708140The cAMP pathway regulates mRNA decay through phosphorylation of the RNA-binding protein TIS11b/BRF1.Mol Biol Cell2016 Dec 1Rataj F-
27102483RNA-binding proteins ZFP36L1 and ZFP36L2 promote cell quiescence.Science2016 Apr 22Galloway Adoi: 10.1126/science.aad5978.
27566829The RNA-Binding Proteins Zfp36l1 and Zfp36l2 Enforce the Thymic β-Selection Checkpoint by Limiting DNA Damage Response Signaling and Cell Cycle Progression.J Immunol2016 Oct 1Vogel KUdoi: 10.4049/jimmunol.1600854
26280535mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype.Nat Cell Biol2015 SepHerranz Ndoi: 10.1038/ncb3225
28394372Maintenance of the marginal-zone B cell compartment specifically requires the RNA-binding protein ZFP36L1.Nat Immunol2017 JunNewman Rdoi: 10.1038/ni.3724
28891815RNA-binding protein ZFP36L1 maintains posttranscriptional regulation of bile acid metabolism.J Clin Invest2017 Oct 2Tarling EJdoi: 10.1172/JCI94029
29880481Reciprocal Regulation of DUSP9 and DUSP16 Expression by HIF1 Controls ERK and p38 MAP Kinase Activity and Mediates Chemotherapy-Induced Breast Cancer Stem Cell Enrichment.Cancer Res2018 Aug 1Lu Hdoi: 10.1158/0008-5472.CAN-18-0270
30449617A Membraneless Organelle Associated with the Endoplasmic Reticulum Enables 3'UTR-Mediated Protein-Protein Interactions.Cell2018 Nov 29Ma Wdoi: 10.1016/j.cell.2018.10.007
30526691The RNA-binding proteins Zfp36l1 and Zfp36l2 act redundantly in myogenesis.Skelet Muscle2018 Dec 7Bye-A-Jee Hdoi: 10.1186/s13395-018-0183-9.
30622281RNA-binding protein ZFP36L1 regulates osteoarthritis by modulating members of the heat shock protein 70 family.Nat Commun2019 Jan 8Son YOdoi: 10.1038/s41467-018-08035-7.
Expression
Transcripts
Transcript IDNameLengthRefSeq ID Protein IDLengthRefSeq IDUniportKB ID
ENST00000557022ZFP36L1-205577-ENSP00000450600176 (aa)-G3V2D5
ENST00000557086ZFP36L1-206727-ENSP00000450784207 (aa)-G3V2P5
ENST00000439696ZFP36L1-2023190-ENSP00000388402338 (aa)-Q07352
ENST00000336440ZFP36L1-2013026-ENSP00000337386338 (aa)-Q07352
ENST00000555997ZFP36L1-2043094-ENSP0000045109369 (aa)-G3V382
ENST00000553375ZFP36L1-203633-ENSP00000452119189 (aa)-G3V515
Gene Model
Click here to download ENSG00000185650's gene model file
Pathways
Pathway IDPathway NameSource
hsa04218Cellular senescenceKEGG
Phenotypes
ensgIDTraitpValuePubmed ID
ENSG00000185650Platelet Function Tests1.2086900E-005-
ENSG00000185650Age-Related Hearing Impairment 18E-924939585
ENSG00000185650Inflammatory Bowel Diseases1E-826192919
ENSG00000185650Diabetes Mellitus, Type 12E-1219430480
ENSG00000185650Fibrinogen1E-823969696
ENSG00000185650Fibrinogen4E-1328107422
ENSG00000185650Inflammatory Bowel Diseases3E-1023128233
ENSG00000185650Crohn Disease1E-726192919
ENSG00000185650Fibrinogen8E-1428107422
ENSG00000185650Fibrinogen2E-1226561523
ENSG00000185650Celiac Disease4E-720190752
ENSG00000185650Multiple Sclerosis9E-1221833088
GWAS
ensgIDSNPChromosomePositionSNP-risk TraitPubmedID95% CIOr or BEAT EFO ID
ENSG00000185650rs22362621468794755AMultiple sclerosis240766021.08EFO_0003885
ENSG00000185650rs118514141468792785?Celiac disease220572351.13EFO_0001060
ENSG00000185650rs38255681468793871?Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)23603761[1.19-1.43]1.2987013EFO_1001999|EFO_1002020|EFO_1002019
ENSG00000185650rs577863421468793311GMacrophage inflammatory protein 1a levels27989323[0.076-0.187] SD units decrease0.1314EFO_0008218
ENSG00000185650rs128890061468793846?Respiratory diseases30595370EFO_0000684
ENSG00000185650rs9272921468792124?Red cell distribution width30595370EFO_0005192
ENSG00000185650rs22362621468794755?Systolic blood pressure30595370EFO_0006335
ENSG00000185650rs577863421468793311GDiastolic blood pressure30224653[0.1-0.185] mmHg decrease0.1423EFO_0006336
Protein-Protein Interaction (PPI)

Clik here to download ENSG00000185650's network

* RBP PPI network refers to all genes directly bind to RBP
Paralogs
Ensembl IDGene SymbolCoverageIdentiy ParalogGene SymbolCoverageIdentiy
ENSG00000185650ZFP36L16075.893ENSG00000152518ZFP36L27560.241
Orthologs
Ensembl IDGene SymbolCoverageIdentiy OrthologGene SymbolCoverageIdentiy Species
ENSG00000185650ZFP36L17136.877ENSAPOG00000014920zgc:1627306836.545Acanthochromis_polyacanthus
ENSG00000185650ZFP36L19068.391ENSAPOG00000020931zfp36l1a10058.205Acanthochromis_polyacanthus
ENSG00000185650ZFP36L16739.286ENSAPOG00000014912zgc:1141306438.869Acanthochromis_polyacanthus
ENSG00000185650ZFP36L110098.817ENSAMEG00000014353ZFP36L110098.817Ailuropoda_melanoleuca
ENSG00000185650ZFP36L19962.371ENSACIG00000016314zfp36l1a10059.621Amphilophus_citrinellus
ENSG00000185650ZFP36L16745.594ENSACIG00000009027sb:cb816245.420Amphilophus_citrinellus
ENSG00000185650ZFP36L19068.208ENSAOCG00000019239zfp36l1a10058.098Amphiprion_ocellaris
ENSG00000185650ZFP36L17136.545ENSAOCG00000002001zgc:1627306836.545Amphiprion_ocellaris
ENSG00000185650ZFP36L19068.208ENSAPEG00000010246zfp36l1a10058.098Amphiprion_percula
ENSG00000185650ZFP36L17136.545ENSAPEG00000015490zgc:1627307136.545Amphiprion_percula
ENSG00000185650ZFP36L17143.066ENSATEG00000003462sb:cb816442.909Anabas_testudineus
ENSG00000185650ZFP36L19068.208ENSATEG00000004546zfp36l1a10057.841Anabas_testudineus
ENSG00000185650ZFP36L19966.845ENSATEG00000014086zfp36l1b10057.784Anabas_testudineus
ENSG00000185650ZFP36L110099.408ENSANAG00000037142ZFP36L110099.408Aotus_nancymaae
ENSG00000185650ZFP36L16745.769ENSACLG00000013759sb:cb816245.977Astatotilapia_calliptera
ENSG00000185650ZFP36L19066.092ENSACLG00000007768zfp36l1a10056.154Astatotilapia_calliptera
ENSG00000185650ZFP36L19072.674ENSAMXG00000036093zfp36l1a9960.825Astyanax_mexicanus
ENSG00000185650ZFP36L19363.158ENSAMXG00000029887zfp36l1b10053.279Astyanax_mexicanus
ENSG00000185650ZFP36L19346.341ENSAMXG00000034874sb:cb819441.470Astyanax_mexicanus
ENSG00000185650ZFP36L16741.270ENSAMXG00000035945zgc:1627306841.667Astyanax_mexicanus
ENSG00000185650ZFP36L16744.106ENSAMXG00000038581zgc:1141306445.283Astyanax_mexicanus
ENSG00000185650ZFP36L110099.112ENSBTAG00000025434ZFP36L110099.112Bos_taurus
ENSG00000185650ZFP36L110099.408ENSCJAG00000042187ZFP36L110099.408Callithrix_jacchus
ENSG00000185650ZFP36L110098.295ENSCAFG00000016497ZFP36L110098.225Canis_familiaris
ENSG00000185650ZFP36L110098.295ENSCAFG00020005951ZFP36L110098.225Canis_lupus_dingo
ENSG00000185650ZFP36L110099.112ENSCHIG00000022716ZFP36L110099.112Capra_hircus
ENSG00000185650ZFP36L110098.225ENSTSYG00000034276ZFP36L110098.225Carlito_syrichta
ENSG00000185650ZFP36L110097.727ENSCAPG00000005988ZFP36L19895.783Cavia_aperea
ENSG00000185650ZFP36L110098.521ENSCPOG00000040127ZFP36L110098.521Cavia_porcellus
ENSG00000185650ZFP36L110099.704ENSCCAG00000007439ZFP36L110099.704Cebus_capucinus
ENSG00000185650ZFP36L110099.408ENSCATG00000043529ZFP36L110099.408Cercocebus_atys
ENSG00000185650ZFP36L110098.225ENSCLAG00000003695ZFP36L110098.225Chinchilla_lanigera
ENSG00000185650ZFP36L110099.704ENSCSAG00000013114ZFP36L110099.704Chlorocebus_sabaeus
ENSG00000185650ZFP36L110089.266ENSCPBG00000021516ZFP36L110086.510Chrysemys_picta_bellii
ENSG00000185650ZFP36L110099.704ENSCANG00000031505ZFP36L110099.704Colobus_angolensis_palliatus
ENSG00000185650ZFP36L110098.817ENSCGRG00001010926Zfp36l110098.817Cricetulus_griseus_chok1gshd
ENSG00000185650ZFP36L110098.521ENSCGRG00000007735Zfp36l110098.521Cricetulus_griseus_crigri
ENSG00000185650ZFP36L110056.777ENSCSEG00000007039zfp36l1a10057.033Cynoglossus_semilaevis
ENSG00000185650ZFP36L16743.083ENSCSEG00000018283zgc:1627309534.234Cynoglossus_semilaevis
ENSG00000185650ZFP36L19962.944ENSCVAG00000008482zfp36l1a10055.897Cyprinodon_variegatus
ENSG00000185650ZFP36L19354.645ENSCVAG00000020132-9746.814Cyprinodon_variegatus
ENSG00000185650ZFP36L16743.373ENSDARG00000103720zgc:1627307244.000Danio_rerio
ENSG00000185650ZFP36L16748.148ENSDARG00000040725zgc:1141306248.178Danio_rerio
ENSG00000185650ZFP36L18647.644ENSDARG00000040503sb:cb819042.373Danio_rerio
ENSG00000185650ZFP36L19964.767ENSDARG00000016154zfp36l1a10058.763Danio_rerio
ENSG00000185650ZFP36L19861.905ENSDARG00000021443zfp36l1b9958.919Danio_rerio
ENSG00000185650ZFP36L110097.159ENSDNOG00000005159ZFP36L110098.084Dasypus_novemcinctus
ENSG00000185650ZFP36L110098.817ENSDORG00000029853Zfp36l110098.817Dipodomys_ordii
ENSG00000185650ZFP36L110098.817ENSEASG00005008760ZFP36L110098.817Equus_asinus_asinus
ENSG00000185650ZFP36L110098.817ENSECAG00000018860ZFP36L110098.817Equus_caballus
ENSG00000185650ZFP36L19739.276ENSELUG00000013151zgc:1141309539.276Esox_lucius
ENSG00000185650ZFP36L16743.307ENSELUG00000013158zgc:1627306843.307Esox_lucius
ENSG00000185650ZFP36L19957.320ENSELUG00000021506zfp36l1a9958.025Esox_lucius
ENSG00000185650ZFP36L16748.498ENSELUG00000013045sb:cb816348.069Esox_lucius
ENSG00000185650ZFP36L19467.213ENSELUG00000008675zfp36l1b10059.126Esox_lucius
ENSG00000185650ZFP36L110099.112ENSFCAG00000026617ZFP36L110099.112Felis_catus
ENSG00000185650ZFP36L110089.266ENSFALG00000015146ZFP36L110087.812Ficedula_albicollis
ENSG00000185650ZFP36L110098.225ENSFDAG00000014938ZFP36L110098.225Fukomys_damarensis
ENSG00000185650ZFP36L19068.786ENSFHEG00000001313zfp36l1a10055.928Fundulus_heteroclitus
ENSG00000185650ZFP36L16747.126ENSFHEG00000022187sb:cb816247.710Fundulus_heteroclitus
ENSG00000185650ZFP36L15759.000ENSGMOG00000006664zfp36l1b5060.000Gadus_morhua
ENSG00000185650ZFP36L110088.136ENSGALG00000039228ZFP36L110086.510Gallus_gallus
ENSG00000185650ZFP36L19743.684ENSGAFG00000015700sb:cb819843.307Gambusia_affinis
ENSG00000185650ZFP36L18868.023ENSGAFG00000018711zfp36l1a10055.216Gambusia_affinis
ENSG00000185650ZFP36L19764.583ENSGACG00000011271zfp36l1a9958.808Gasterosteus_aculeatus
ENSG00000185650ZFP36L110089.831ENSGAGG00000007315ZFP36L110086.510Gopherus_agassizii
ENSG00000185650ZFP36L1100100.000ENSGGOG00000041615ZFP36L1100100.000Gorilla_gorilla
ENSG00000185650ZFP36L16745.769ENSHBUG00000002383sb:cb816145.594Haplochromis_burtoni
ENSG00000185650ZFP36L19066.092ENSHBUG00000016051zfp36l1a10056.154Haplochromis_burtoni
ENSG00000185650ZFP36L110098.521ENSHGLG00000016491ZFP36L110098.521Heterocephalus_glaber_female
ENSG00000185650ZFP36L110098.521ENSHGLG00100018163ZFP36L110098.521Heterocephalus_glaber_male
ENSG00000185650ZFP36L110060.104ENSHCOG00000013932zfp36l1a10060.104Hippocampus_comes
ENSG00000185650ZFP36L15755.882ENSHCOG00000012747zfp36l1b9255.882Hippocampus_comes
ENSG00000185650ZFP36L16742.366ENSIPUG00000018248zgc:1627307042.748Ictalurus_punctatus
ENSG00000185650ZFP36L19967.708ENSIPUG00000023681ZFP36L19960.104Ictalurus_punctatus
ENSG00000185650ZFP36L19739.323ENSIPUG00000011378sb:cb819841.842Ictalurus_punctatus
ENSG00000185650ZFP36L16643.038ENSIPUG00000018256zgc:1141305345.188Ictalurus_punctatus
ENSG00000185650ZFP36L110099.408ENSSTOG00000009758ZFP36L110099.408Ictidomys_tridecemlineatus
ENSG00000185650ZFP36L110097.159ENSJJAG00000017247Zfp36l19198.077Jaculus_jaculus
ENSG00000185650ZFP36L19068.786ENSKMAG00000013156zfp36l1a10056.812Kryptolebias_marmoratus
ENSG00000185650ZFP36L16741.696ENSLBEG00000018387zgc:1141306542.199Labrus_bergylta
ENSG00000185650ZFP36L19963.542ENSLBEG00000008102zfp36l1a8960.511Labrus_bergylta
ENSG00000185650ZFP36L110065.278ENSLACG00000015967ZFP36L110065.556Latimeria_chalumnae
ENSG00000185650ZFP36L18144.693ENSLACG00000015980-9238.504Latimeria_chalumnae
ENSG00000185650ZFP36L16851.230ENSLACG00000015732sb:cb819842.507Latimeria_chalumnae
ENSG00000185650ZFP36L19950.498ENSLACG00000012879-9951.244Latimeria_chalumnae
ENSG00000185650ZFP36L110045.667ENSLOCG00000016446-9745.667Lepisosteus_oculatus
ENSG00000185650ZFP36L16741.313ENSLOCG00000014597zgc:1627308637.920Lepisosteus_oculatus
ENSG00000185650ZFP36L19672.376ENSLOCG00000013957zfp36l1a10065.600Lepisosteus_oculatus
ENSG00000185650ZFP36L17046.442ENSLOCG00000014587sb:cb816646.237Lepisosteus_oculatus
ENSG00000185650ZFP36L110098.864ENSLAFG00000028594ZFP36L110098.521Loxodonta_africana
ENSG00000185650ZFP36L110099.704ENSMFAG00000033125ZFP36L110099.704Macaca_fascicularis
ENSG00000185650ZFP36L110099.704ENSMMUG00000044603ZFP36L110099.704Macaca_mulatta
ENSG00000185650ZFP36L110099.432ENSMNEG00000032614ZFP36L110097.929Macaca_nemestrina
ENSG00000185650ZFP36L110099.408ENSMLEG00000044247ZFP36L110099.408Mandrillus_leucophaeus
ENSG00000185650ZFP36L19068.235ENSMAMG00000000274zfp36l1a8858.901Mastacembelus_armatus
ENSG00000185650ZFP36L19066.092ENSMZEG00005014679zfp36l1a10056.154Maylandia_zebra
ENSG00000185650ZFP36L16746.332ENSMZEG00005016001-6145.594Maylandia_zebra
ENSG00000185650ZFP36L16746.304ENSMZEG00005024684sb:cb816146.512Maylandia_zebra
ENSG00000185650ZFP36L110098.817ENSMAUG00000020087Zfp36l110098.817Mesocricetus_auratus
ENSG00000185650ZFP36L110099.112ENSMICG00000037296ZFP36L110099.112Microcebus_murinus
ENSG00000185650ZFP36L110098.521ENSMOCG00000003189Zfp36l110098.521Microtus_ochrogaster
ENSG00000185650ZFP36L19068.786ENSMMOG00000011231zfp36l1a9958.140Mola_mola
ENSG00000185650ZFP36L16743.939ENSMMOG00000010073sb:cb816645.382Mola_mola
ENSG00000185650ZFP36L110084.956ENSMODG00000010122ZFP36L110084.071Monodelphis_domestica
ENSG00000185650ZFP36L19167.429ENSMALG00000021238zfp36l1a10058.639Monopterus_albus
ENSG00000185650ZFP36L19466.292ENSMALG00000016768zfp36l1b10052.770Monopterus_albus
ENSG00000185650ZFP36L110098.521MGP_CAROLIEiJ_G0017893Zfp36l110098.521Mus_caroli
ENSG00000185650ZFP36L110098.521ENSMUSG00000021127Zfp36l110098.521Mus_musculus
ENSG00000185650ZFP36L110098.521MGP_PahariEiJ_G0029649Zfp36l110098.521Mus_pahari
ENSG00000185650ZFP36L110098.521MGP_SPRETEiJ_G0018738Zfp36l110098.521Mus_spretus
ENSG00000185650ZFP36L110092.308ENSMPUG00000007282ZFP36L110092.308Mustela_putorius_furo
ENSG00000185650ZFP36L110098.817ENSNGAG00000024367Zfp36l110098.817Nannospalax_galili
ENSG00000185650ZFP36L18640.741ENSNBRG00000006231sb:cb818941.643Neolamprologus_brichardi
ENSG00000185650ZFP36L110056.410ENSNBRG00000010827zfp36l1a10056.154Neolamprologus_brichardi
ENSG00000185650ZFP36L1100100.000ENSNLEG00000001046ZFP36L110099.704Nomascus_leucogenys
ENSG00000185650ZFP36L110094.915ENSMEUG00000003070ZFP36L110094.690Notamacropus_eugenii
ENSG00000185650ZFP36L110098.521ENSODEG00000014162ZFP36L110098.521Octodon_degus
ENSG00000185650ZFP36L110058.090ENSONIG00000000973zfp36l1a10057.825Oreochromis_niloticus
ENSG00000185650ZFP36L16744.358ENSONIG00000001259sb:cb816144.788Oreochromis_niloticus
ENSG00000185650ZFP36L110096.450ENSOCUG00000003168ZFP36L110096.450Oryctolagus_cuniculus
ENSG00000185650ZFP36L16745.736ENSORLG00000024026sb:cb818439.163Oryzias_latipes
ENSG00000185650ZFP36L19069.006ENSORLG00000029605zfp36l1a10058.486Oryzias_latipes
ENSG00000185650ZFP36L19964.398ENSORLG00020021609zfp36l1a10058.793Oryzias_latipes_hni
ENSG00000185650ZFP36L19069.006ENSORLG00015019460zfp36l1a10058.486Oryzias_latipes_hsok
ENSG00000185650ZFP36L19068.571ENSOMEG00000018296zfp36l1a10058.140Oryzias_melastigma
ENSG00000185650ZFP36L15167.778ENSOMEG00000017752zgc:1627306739.024Oryzias_melastigma
ENSG00000185650ZFP36L19357.222ENSOMEG00000001264-9747.277Oryzias_melastigma
ENSG00000185650ZFP36L110097.929ENSOGAG00000010033ZFP36L110097.929Otolemur_garnettii
ENSG00000185650ZFP36L110082.840ENSOARG00000021177ZFP36L110082.840Ovis_aries
ENSG00000185650ZFP36L110099.704ENSPPAG00000027452ZFP36L110099.704Pan_paniscus
ENSG00000185650ZFP36L110099.112ENSPPRG00000015094ZFP36L110099.112Panthera_pardus
ENSG00000185650ZFP36L110086.686ENSPTIG00000019155ZFP36L110086.686Panthera_tigris_altaica
ENSG00000185650ZFP36L110099.704ENSPTRG00000051193ZFP36L110099.704Pan_troglodytes
ENSG00000185650ZFP36L110099.704ENSPANG00000009731ZFP36L110099.704Papio_anubis
ENSG00000185650ZFP36L19471.429ENSPKIG00000009504-10061.538Paramormyrops_kingsleyae
ENSG00000185650ZFP36L19969.312ENSPKIG00000007298ZFP36L110060.950Paramormyrops_kingsleyae
ENSG00000185650ZFP36L110089.831ENSPSIG00000008151ZFP36L110088.270Pelodiscus_sinensis
ENSG00000185650ZFP36L16747.521ENSPMGG00000009232sb:cb817947.521Periophthalmus_magnuspinnatus
ENSG00000185650ZFP36L110062.117ENSPMGG00000000442zfp36l1a10061.838Periophthalmus_magnuspinnatus
ENSG00000185650ZFP36L15064.865ENSPMGG00000011911zgc:1627305862.500Periophthalmus_magnuspinnatus
ENSG00000185650ZFP36L110098.521ENSPEMG00000011361Zfp36l110098.521Peromyscus_maniculatus_bairdii
ENSG00000185650ZFP36L110094.395ENSPCIG00000019895ZFP36L18894.395Phascolarctos_cinereus
ENSG00000185650ZFP36L19741.995ENSPFOG00000013806sb:cb819842.147Poecilia_formosa
ENSG00000185650ZFP36L19066.480ENSPFOG00000017436zfp36l1a10054.684Poecilia_formosa
ENSG00000185650ZFP36L19068.235ENSPLAG00000005641zfp36l1a10055.065Poecilia_latipinna
ENSG00000185650ZFP36L17954.217ENSPLAG00000020158sb:cb819644.543Poecilia_latipinna
ENSG00000185650ZFP36L19066.480ENSPMEG00000013028zfp36l1a10054.822Poecilia_mexicana
ENSG00000185650ZFP36L18184.211ENSPMEG00000022425sb:cb819842.147Poecilia_mexicana
ENSG00000185650ZFP36L19068.639ENSPREG00000013484zfp36l1a10055.729Poecilia_reticulata
ENSG00000185650ZFP36L19740.104ENSPREG00000017495sb:cb819841.470Poecilia_reticulata
ENSG00000185650ZFP36L110099.704ENSPPYG00000005933ZFP36L110099.704Pongo_abelii
ENSG00000185650ZFP36L110099.112ENSPCAG00000005383ZFP36L110099.112Procavia_capensis
ENSG00000185650ZFP36L110098.864ENSPCOG00000022518ZFP36L110098.817Propithecus_coquereli
ENSG00000185650ZFP36L110097.159ENSPVAG00000011686ZFP36L110097.806Pteropus_vampyrus
ENSG00000185650ZFP36L19066.092ENSPNYG00000004953zfp36l1a10056.154Pundamilia_nyererei
ENSG00000185650ZFP36L18640.336ENSPNYG00000007502sb:cb819839.798Pundamilia_nyererei
ENSG00000185650ZFP36L19041.000ENSPNAG00000023029zgc:1141306542.125Pygocentrus_nattereri
ENSG00000185650ZFP36L19742.199ENSPNAG00000030063sb:cb819443.324Pygocentrus_nattereri
ENSG00000185650ZFP36L19664.773ENSPNAG00000000386zfp36l1b9856.620Pygocentrus_nattereri
ENSG00000185650ZFP36L16742.975ENSPNAG00000023018zgc:1627306942.975Pygocentrus_nattereri
ENSG00000185650ZFP36L19469.231ENSPNAG00000015712zfp36l1a9960.363Pygocentrus_nattereri
ENSG00000185650ZFP36L110098.521ENSRNOG00000058646Zfp36l110098.521Rattus_norvegicus
ENSG00000185650ZFP36L110099.432ENSRBIG00000040496-9898.758Rhinopithecus_bieti
ENSG00000185650ZFP36L110099.704ENSRROG00000040595ZFP36L110099.704Rhinopithecus_roxellana
ENSG00000185650ZFP36L110099.704ENSSBOG00000025671ZFP36L110099.704Saimiri_boliviensis_boliviensis
ENSG00000185650ZFP36L110094.915ENSSHAG00000011647ZFP36L110094.395Sarcophilus_harrisii
ENSG00000185650ZFP36L19669.444ENSSFOG00015002575-9959.200Scleropages_formosus
ENSG00000185650ZFP36L19666.129ENSSFOG00015020649ZFP36L110061.433Scleropages_formosus
ENSG00000185650ZFP36L16738.866ENSSFOG00015003179sb:cb819834.257Scleropages_formosus
ENSG00000185650ZFP36L19066.286ENSSMAG00000012821zfp36l1a6555.416Scophthalmus_maximus
ENSG00000185650ZFP36L18363.226ENSSMAG00000018208-9850.314Scophthalmus_maximus
ENSG00000185650ZFP36L19366.102ENSSDUG00000001019zfp36l1b9955.914Seriola_dumerili
ENSG00000185650ZFP36L19068.208ENSSDUG00000009669zfp36l1a10057.841Seriola_dumerili
ENSG00000185650ZFP36L19068.208ENSSLDG00000021382zfp36l1a10057.841Seriola_lalandi_dorsalis
ENSG00000185650ZFP36L110055.556ENSSLDG00000011048zfp36l1b9954.447Seriola_lalandi_dorsalis
ENSG00000185650ZFP36L110087.006ENSSPUG00000002037ZFP36L110086.510Sphenodon_punctatus
ENSG00000185650ZFP36L19068.208ENSSPAG00000010371zfp36l1a10058.355Stegastes_partitus
ENSG00000185650ZFP36L17135.880ENSSPAG00000006851zgc:1627306836.213Stegastes_partitus
ENSG00000185650ZFP36L110099.408ENSSSCG00000028304ZFP36L110099.408Sus_scrofa
ENSG00000185650ZFP36L17781.439ENSTGUG00000011494ZFP36L110081.439Taeniopygia_guttata
ENSG00000185650ZFP36L19068.208ENSTRUG00000022418zfp36l110057.841Takifugu_rubripes
ENSG00000185650ZFP36L19739.055ENSTRUG00000020720sb:cb819840.547Takifugu_rubripes
ENSG00000185650ZFP36L19960.615ENSTNIG00000002277zfp36l1a10060.615Tetraodon_nigroviridis
ENSG00000185650ZFP36L17039.223ENSTNIG00000000183zgc:1627307139.100Tetraodon_nigroviridis
ENSG00000185650ZFP36L16743.651ENSTNIG00000019802sb:cb817646.122Tetraodon_nigroviridis
ENSG00000185650ZFP36L110099.112ENSTTRG00000003475ZFP36L110099.112Tursiops_truncatus
ENSG00000185650ZFP36L110099.112ENSUAMG00000010751ZFP36L110099.112Ursus_americanus
ENSG00000185650ZFP36L110099.112ENSUMAG00000010126ZFP36L110099.112Ursus_maritimus
ENSG00000185650ZFP36L110097.929ENSVVUG00000003551ZFP36L110097.929Vulpes_vulpes
ENSG00000185650ZFP36L110073.770ENSXETG00000016987zfp36l110074.148Xenopus_tropicalis
ENSG00000185650ZFP36L16452.941ENSXETG00000023255zfp36l2.16352.941Xenopus_tropicalis
ENSG00000185650ZFP36L16156.322ENSXETG00000023254zfp36l2.25060.811Xenopus_tropicalis
ENSG00000185650ZFP36L18161.290ENSXCOG00000010688sb:cb818642.411Xiphophorus_couchianus
ENSG00000185650ZFP36L18869.186ENSXCOG00000001799zfp36l1a10055.102Xiphophorus_couchianus
ENSG00000185650ZFP36L19742.818ENSXMAG00000004681sb:cb819842.973Xiphophorus_maculatus
ENSG00000185650ZFP36L18868.786ENSXMAG00000022234zfp36l1a10055.216Xiphophorus_maculatus
Gene Ontology
Go IDGo_termPubmedIDEvidenceCategory
GO:0000165MAPK cascade18326031.20166898.IDAProcess
GO:0000288nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay-IEAProcess
GO:0000932P-body17369404.IDAComponent
GO:0000981DNA-binding transcription factor activity, RNA polymerase II-specific19274049.ISMFunction
GO:0001570vasculogenesis-IEAProcess
GO:0003342proepicardium development-IEAProcess
GO:0003677DNA binding-IEAFunction
GO:0003700DNA-binding transcription factor activity8595910.NASFunction
GO:0003723RNA binding22658674.HDAFunction
GO:0003729mRNA binding15467755.IDAFunction
GO:0003730mRNA 3'-UTR binding21873635.IBAFunction
GO:0005515protein binding15687258.16189514.18326031.25106868.IPIFunction
GO:0005634nucleus12198173.21832157.IDAComponent
GO:0005737cytoplasm12198173.IDAComponent
GO:0005829cytosol21873635.IBAComponent
GO:0005829cytosol-TASComponent
GO:0006357regulation of transcription by RNA polymerase II-IEAProcess
GO:0006397mRNA processing-IEAProcess
GO:0006915apoptotic process-IEAProcess
GO:0007507heart development-IEAProcess
GO:0008283cell proliferation-IEAProcess
GO:0009611response to wounding27182009.IDAProcess
GO:0010468regulation of gene expression20166898.IDAProcess
GO:0010837regulation of keratinocyte proliferation27182009.IMPProcess
GO:0014065phosphatidylinositol 3-kinase signaling15538381.IDAProcess
GO:0021915neural tube development-IEAProcess
GO:0031086nuclear-transcribed mRNA catabolic process, deadenylation-independent decay-ISSProcess
GO:0031440regulation of mRNA 3'-end processing21832157.IDAProcess
GO:0032869cellular response to insulin stimulus15538381.IDAProcess
GO:0033077T cell differentiation in thymus-ISSProcess
GO:0035264multicellular organism growth-IEAProcess
GO:0035925mRNA 3'-UTR AU-rich region binding12198173.15467755.15538381.18326031.19179481.20702587.21832157.24700863.25014217.25106868.26542173.IDAFunction
GO:0038066p38MAPK cascade-ISSProcess
GO:0043488regulation of mRNA stability15467755.15538381.15687258.18326031.19179481.20702587.24700863.25014217.26542173.IDAProcess
GO:0043488regulation of mRNA stability12198173.25106868.IMPProcess
GO:0043488regulation of mRNA stability-TASProcess
GO:0043491protein kinase B signaling-ISSProcess
GO:0044344cellular response to fibroblast growth factor stimulus-ISSProcess
GO:0045577regulation of B cell differentiation-ISSProcess
GO:0045600positive regulation of fat cell differentiation-ISSProcess
GO:0045616regulation of keratinocyte differentiation27182009.IMPProcess
GO:0045647negative regulation of erythrocyte differentiation20702587.IDAProcess
GO:0045657positive regulation of monocyte differentiation26542173.IDAProcess
GO:0045661regulation of myoblast differentiation-ISSProcess
GO:0046872metal ion binding-IEAFunction
GO:0048382mesendoderm development-ISSProcess
GO:0051028mRNA transport17369404.IMPProcess
GO:0060710chorio-allantoic fusion-IEAProcess
GO:0060712spongiotrophoblast layer development-IEAProcess
GO:00611583'-UTR-mediated mRNA destabilization21873635.IBAProcess
GO:00611583'-UTR-mediated mRNA destabilization15467755.15538381.15687258.18326031.19179481.24700863.26542173.IDAProcess
GO:00611583'-UTR-mediated mRNA destabilization12198173.25014217.25106868.IMPProcess
GO:0070371ERK1 and ERK2 cascade25106868.IDAProcess
GO:0071320cellular response to cAMP19179481.IDAProcess
GO:0071356cellular response to tumor necrosis factor20166898.IDAProcess
GO:0071364cellular response to epidermal growth factor stimulus20166898.IDAProcess
GO:0071375cellular response to peptide hormone stimulus15467755.19179481.IDAProcess
GO:0071385cellular response to glucocorticoid stimulus20166898.IDAProcess
GO:0071456cellular response to hypoxia21832157.IMPProcess
GO:0071472cellular response to salt stress-ISSProcess
GO:0071560cellular response to transforming growth factor beta stimulus20166898.IDAProcess
GO:007188914-3-3 protein binding15538381.18326031.IDAFunction
GO:0072091regulation of stem cell proliferation-ISSProcess
GO:0097403cellular response to raffinose-ISSProcess
GO:1900153positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay-ISSProcess
GO:1901991negative regulation of mitotic cell cycle phase transition-ISSProcess
GO:1902172regulation of keratinocyte apoptotic process27182009.IMPProcess
GO:1904582positive regulation of intracellular mRNA localization17369404.IMPProcess
GO:1990904ribonucleoprotein complex15687258.20702587.21832157.26542173.IDAComponent
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