EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr14	68789825	Missense_Mutation	novel	T242S	0.15
BLCA	chr14	68789856	Silent	novel	L232L	0.34
BLCA	chr14	68792952	5'UTR	novel		0.28
BLCA	chr14	68793044	5'UTR	novel		0.33
BLCA	chr14	68790451	Frame_Shift_Ins	NA	*C34Lfs41**	0.98
BLCA	chr14	68789653	Silent	novel	L299L	0.32
BLCA	chr14	68790275	Nonsense_Mutation	novel	S92*	0.29
BLCA	chr14	68790399	Missense_Mutation	novel	R51W	0.29
BLCA	chr14	68789956	Frame_Shift_Ins	novel	*Q199Pfs3**	0.53
BLCA	chr14	68789670	Frame_Shift_Ins	novel	*S294Qfs45**	0.26
BLCA	chr14	68789913	Frame_Shift_Ins	novel	*T213Hfs24**	0.19
BLCA	chr14	68790031	Nonsense_Mutation	novel	C173*	0.92	zf-CCCH
BLCA	chr14	68792884	Nonsense_Mutation	novel	K19*	0.48
BLCA	chr14	68796343	5'Flank	novel		0.35
BLCA	chr14	68789738	Frame_Shift_Del	NA	*G271Vfs36**	0.5
BLCA	chr14	68790119	Frame_Shift_Del	novel	*F137Sfs4**	0.3
BLCA	chr14	68790044	Missense_Mutation	novel	Y169C	0.35	zf-CCCH
BLCA	chr14	68789861	Frame_Shift_Del	novel	*P230Lfs3**	0.42
BLCA	chr14	68792889	Frame_Shift_Del	novel	*F11Yfs63**	0.31
BLCA	chr14	68790389	Nonsense_Mutation	NA	S54*	0.31
BLCA	chr14	68790266	Missense_Mutation	novel	G95V	0.45
BLCA	chr14	68796089	5'Flank	NA		0.35
BLCA	chr14	68789965	Frame_Shift_Ins	novel	*P196Sfs6**	0.73
BLCA	chr14	68790067	Frame_Shift_Ins	novel	*H162Pfs19**	0.21	zf-CCCH
BLCA	chr14	68790318	Frame_Shift_Ins	novel	*A78Pfs3**	0.21
BLCA	chr14	68790424	Frame_Shift_Ins	novel	*T43Hfs32**	0.15
BLCA	chr14	68795983	5'Flank	NA		0.14
BLCA	chr14	68790130	Frame_Shift_Ins	novel	*I141Hfs40**	0.5
BLCA	chr14	68789994	Missense_Mutation	NA	A186T	0.21
BLCA	chr14	68789734	Frame_Shift_Ins	novel	*S273Lfs18**	0.17
BLCA	chr14	68789826	Frame_Shift_Ins	novel	*T242Lfs66**	0.09
BLCA	chr14	68790209	Frame_Shift_Ins	novel	*R114Qfs12**	0.18
BLCA	chr14	68789582	Frame_Shift_Ins	novel	*N323Tfs40**	0.26
BLCA	chr14	68790333	Missense_Mutation	novel	G73S	0.42
BLCA	chr14	68789951	Frame_Shift_Ins	novel	*H200Rfs34**	0.33
BLCA	chr14	68796176	5'Flank	rs771102502		0.18
BLCA	chr14	68789817	Frame_Shift_Ins	novel	*D245Rfs5**	0.4
BLCA	chr14	68795840	5'Flank	NA		0.49
BLCA	chr14	68789616	Missense_Mutation	rs756918933	S312R	0.23
BLCA	chr14	68790264	Frame_Shift_Ins	novel	*E96Rfs29**	0.36
BLCA	chr14	68790291	Missense_Mutation	novel	R87G	0.18
BLCA	chr14	68796329	5'Flank	novel		0.26
BLCA	chr14	68789806	Frame_Shift_Ins	rs775692081	*N248Kfs2**	0.17
BLCA	chr14	68790061	In_Frame_Del	novel	H162_T163del	0.61	zf-CCCH
BLCA	chr14	68792967	5'UTR	novel		0.56
BRCA	chr14	68789642	Frame_Shift_Ins	novel	*E303Gfs36**	0.09
BRCA	chr14	68792894	Frame_Shift_Del	novel	*I10Ffs64**	0.23
BRCA	chr14	68795280	5'Flank	novel		0.33
BRCA	chr14	68790175	Frame_Shift_Del	novel	Y115*	0.22
BRCA	chr14	68789872	Frame_Shift_Ins	novel	*T227Afs11**	0.24
BRCA	chr14	68793068	5'UTR	novel		0.13
BRCA	chr14	68790022	In_Frame_Del	NA	I176del	0.27	zf-CCCH
BRCA	chr14	68790044	Missense_Mutation	NA	Y169S	0.36	zf-CCCH
BRCA	chr14	68790310	Frame_Shift_Del	novel	*P77Rfs67**	0.41
BRCA	chr14	68790207	Frame_Shift_Ins	NA	*Y115Afs34**	0.79
BRCA	chr14	68788593	3'Flank	novel		0.05
BRCA	chr14	68792905	Missense_Mutation	novel	D12N	0.08
BRCA	chr14	68787676	3'Flank	novel		0.5
BRCA	chr14	68790090	Nonsense_Mutation	NA	K154*	0.69	zf-CCCH
BRCA	chr14	68790451	Frame_Shift_Ins	NA	*C34Lfs41**	0.48
BRCA	chr14	68792979	5'UTR	novel		0.21
BRCA	chr14	68790424	Frame_Shift_Ins	novel	*T43Hfs32**	0.26
BRCA	chr14	68787876	3'Flank	novel		0.15
CESC	chr14	68788618	3'UTR	novel		0.49
CESC	chr14	68795977	5'Flank	NA		0.26
CESC	chr14	68789597	Missense_Mutation	NA	S318F	0.1
CESC	chr14	68790058	Silent	NA	I164I	0.09
CESC	chr14	68788617	3'UTR	novel		0.37
CESC	chr14	68788454	3'Flank	novel		0.41
CESC	chr14	68795831	5'Flank	novel		0.52
CESC	chr14	68796436	5'Flank	novel		0.45
CESC	chr14	68790074	Missense_Mutation	novel	R159H	0.44	zf-CCCH
CESC	chr14	68790258	Missense_Mutation	novel	L98M	0.35
CESC	chr14	68789651	Nonsense_Mutation	novel	S300*	0.36
CESC	chr14	68793062	5'UTR	novel		0.4
CESC	chr14	68795800	5'Flank	novel		0.48
CESC	chr14	68796089	5'Flank	NA		0.53
CESC	chr14	68792924	Silent	NA	L5L	0.25
CESC	chr14	68789123	Intron	novel		0.22
CESC	chr14	68787876	3'Flank	novel		0.33
CESC	chr14	68788427	3'Flank	novel		0.25
CESC	chr14	68794958	5'Flank	novel		0.31
CESC	chr14	68792983	5'UTR	novel		0.49
CESC	chr14	68788618	3'UTR	novel		0.27
CESC	chr14	68795644	5'Flank	novel		0.46
CESC	chr14	68795217	5'Flank	novel		0.27
CHOL	chr14	68795259	5'Flank	novel		0.26
COAD	chr14	68789456	Intron	novel		0.35
COAD	chr14	68790069	Missense_Mutation	NA	F161V	0.26	zf-CCCH
COAD	chr14	68795672	5'Flank	novel		0.29
COAD	chr14	68790290	Missense_Mutation	NA	R87Q	0.3
COAD	chr14	68789738	Frame_Shift_Del	NA	*G271Vfs36**	0.32
COAD	chr14	68790094	Silent	NA	K152K	0.56
COAD	chr14	68796238	5'Flank	novel		0.25
COAD	chr14	68789708	Missense_Mutation	NA	P281L	0.14
COAD	chr14	68789671	Frame_Shift_Del	NA	*S294Afs13**	0.33
COAD	chr14	68789848	Silent	rs754764949	A234A	0.3
COAD	chr14	68790042	Missense_Mutation	NA	G170W	0.41	zf-CCCH
COAD	chr14	68796240	5'Flank	novel		0.3
COAD	chr14	68790186	Missense_Mutation	NA	P122S	0.28
COAD	chr14	68789687	Missense_Mutation	NA	M288T	0.23
COAD	chr14	68789297	Intron	novel		0.8
COAD	chr14	68790021	Frame_Shift_Del	NA	*H177Tfs56**	0.79	zf-CCCH
COAD	chr14	68789729	Frame_Shift_Del	NA	*P274Rfs33**	0.26
COAD	chr14	68796240	5'Flank	novel		0.51
DLBC	chr14	68790198	Frame_Shift_Del	novel	*S113Rfs7**	0.16
ESCA	chr14	68796240	5'Flank	novel		0.28
ESCA	chr14	68793006	5'UTR	novel		0.18
ESCA	chr14	68788634	3'UTR	novel		0.42
GBM	chr14	68790344	Frame_Shift_Ins	novel	*S69Tfs17**	0.13
GBM	chr14	68790237	Missense_Mutation	NA	P105S	0.3
HNSC	chr14	68790319	Silent	novel	P77P	0.17
HNSC	chr14	68796279	5'Flank	novel		0.27
HNSC	chr14	68790328	Frame_Shift_Ins	novel	*P75Afs50**	0.36
HNSC	chr14	68789860	Silent	novel	P230P	0.08
HNSC	chr14	68789816	Missense_Mutation	novel	D245V	0.42
HNSC	chr14	68790409	Silent	novel	G47G	0.28
HNSC	chr14	68790303	Missense_Mutation	novel	D83H	0.32
HNSC	chr14	68789851	Silent	rs750342662	S233S	0.09
KIRC	chr14	68789460	Intron	novel		0.17
KIRC	chr14	68789590	Frame_Shift_Del	NA	*L321Wfs41**	0.05
KIRC	chr14	68789511	Intron	novel		0.27
KIRP	chr14	68790115	Silent	novel	R145R	0.41
KIRP	chr14	68790045	Missense_Mutation	novel	Y169H	0.48	zf-CCCH
KIRP	chr14	68792965	5'UTR	novel		0.52
KIRP	chr14	68789774	In_Frame_Del	novel	F251_A259del	0.2
KIRP	chr14	68789632	Silent	novel	L306L	0.42
LAML	chr14	68789649	Missense_Mutation	novel	D301H	0.07
LGG	chr14	68790050	Frame_Shift_Ins	novel	*C167Lfs14**	0.33	zf-CCCH
LGG	chr14	68795798	5'Flank	novel		0.18
LIHC	chr14	68789550	Frame_Shift_Del	novel	*S334Pfs28**	0.07
LIHC	chr14	68789596	Silent	novel	S318S	0.47
LIHC	chr14	68795774	5'Flank	novel		0.25
LIHC	chr14	68789695	Silent	novel	S285S	0.76
LIHC	chr14	68792968	5'UTR	novel		0.22
LIHC	chr14	68789718	Missense_Mutation	NA	L278I	0.57
LIHC	chr14	68792948	5'UTR	novel		0.39
LIHC	chr14	68789578	Silent	novel	S324S	0.14
LIHC	chr14	68795778	5'Flank	novel		0.18
LIHC	chr14	68790039	Missense_Mutation	novel	P171S	0.7	zf-CCCH
LUAD	chr14	68790027	In_Frame_Ins	novel	T163_H174dup	0.07	zf-CCCH
LUAD	chr14	68790067	Missense_Mutation	NA	F161L	0.41	zf-CCCH
LUAD	chr14	68795759	5'Flank	novel		0.53
LUAD	chr14	68789781	Nonsense_Mutation	NA	E257*	0.06
LUAD	chr14	68790036	Missense_Mutation	NA	R172C	0.17	zf-CCCH
LUAD	chr14	68789742	Frame_Shift_Ins	novel	*G270Rfs21**	0.43
LUAD	chr14	68790273	Nonsense_Mutation	NA	E93*	0.15
LUAD	chr14	68792965	5'UTR	novel		0.17
LUAD	chr14	68789781	Nonsense_Mutation	NA	E257*	0.07
LUAD	chr14	68792996	5'UTR	novel		0.29
LUAD	chr14	68789781	Missense_Mutation	NA	E257K	0.29
LUAD	chr14	68790268	Silent	NA	G94G	0.53
LUAD	chr14	68789883	Missense_Mutation	novel	P223S	0.22
LUAD	chr14	68789781	Missense_Mutation	NA	E257K	0.16
LUAD	chr14	68790234	Missense_Mutation	novel	G106W	0.22
LUAD	chr14	68789648	Missense_Mutation	NA	D301V	0.32
LUSC	chr14	68790402	Missense_Mutation	novel	P50S	0.5
LUSC	chr14	68793067	5'UTR	novel		0.2
LUSC	chr14	68795853	5'Flank	novel		0.24
LUSC	chr14	68792906	Missense_Mutation	novel	F11L	0.04
LUSC	chr14	68789817	Missense_Mutation	novel	D245N	0.44
LUSC	chr14	68789919	Missense_Mutation	NA	A211S	0.12
LUSC	chr14	68789883	Frame_Shift_Del	novel	*L219Hfs13**	0.44
LUSC	chr14	68790009	Missense_Mutation	NA	E181Q	0.13
LUSC	chr14	68790061	Silent	novel	T163T	0.3
LUSC	chr14	68790206	Missense_Mutation	novel	Y115C	0.3
LUSC	chr14	68795911	5'Flank	NA		0.13
LUSC	chr14	68789728	Silent	novel	P274P	0.21
LUSC	chr14	68790134	Missense_Mutation	novel	H139L	0.71
LUSC	chr14	68796303	5'Flank	novel		0.13
OV	chr14	68788121	3'Flank	novel		0.88
OV	chr14	68796173	5'Flank	NA		0.21
OV	chr14	68795732	5'Flank	novel		0.36
OV	chr14	68792909	Silent	NA	I10I	0.19
OV	chr14	68790376	Frame_Shift_Del	novel	*S59Afs21**	0.36
PRAD	chr14	68790146	Missense_Mutation	NA	C135F	0.19
PRAD	chr14	68795940	5'Flank	novel		0.36
PRAD	chr14	68789738	Frame_Shift_Del	NA	*G271Vfs36**	0.1
PRAD	chr14	68790003	Missense_Mutation	NA	R183G	0.49
READ	chr14	68789467	Intron	novel		0.42
SARC	chr14	68788059	3'Flank	novel		0.61
SARC	chr14	68787968	3'Flank	novel		0.54
SARC	chr14	68788113	3'Flank	novel		0.29
SARC	chr14	68789671	Frame_Shift_Del	NA	*S294Afs13**	0.36
SKCM	chr14	68796166	5'Flank	NA		0.33
SKCM	chr14	68789719	Silent	NA	F277F	0.25
SKCM	chr14	68790139	Silent	NA	F137F	0.1
SKCM	chr14	68796165	5'Flank	NA		0.3
SKCM	chr14	68795741	5'Flank	novel		0.5
SKCM	chr14	68792896	Missense_Mutation	NA	E15K	0.58
SKCM	chr14	68793022	5'UTR	novel		0.23
SKCM	chr14	68796295	5'Flank	rs770887270		0.09
SKCM	chr14	68789824	Silent	novel	T242T	0.27
SKCM	chr14	68789716	Silent	rs760082533	L278L	0.18
SKCM	chr14	68789716	Silent	rs760082533	L278L	0.45
SKCM	chr14	68790322	Silent	rs752733615	A76A	0.3
SKCM	chr14	68789675	Missense_Mutation	novel	P292L	0.33
SKCM	chr14	68789882	Missense_Mutation	novel	P223L	0.49
STAD	chr14	68796394	5'Flank	novel		0.35
STAD	chr14	68790050	Frame_Shift_Ins	novel	*C167Lfs14**	0.56	zf-CCCH
STAD	chr14	68789880	Frame_Shift_Ins	novel	*T224Hfs13**	0.49
STAD	chr14	68789738	Frame_Shift_Del	NA	*G271Vfs36**	0.14
STAD	chr14	68790230	Frame_Shift_Del	novel	*G107Afs41**	0.26
STAD	chr14	68789738	Frame_Shift_Del	NA	*G271Vfs36**	0.15
STAD	chr14	68789738	Frame_Shift_Del	NA	*G271Vfs36**	0.26
STAD	chr14	68789738	Frame_Shift_Del	NA	*G271Vfs36**	0.19
STAD	chr14	68789689	Silent	novel	H287H	0.43
UCEC	chr14	68792959	5'UTR	novel		0.34
UCEC	chr14	68790210	Missense_Mutation	novel	R114C	0.23
UCEC	chr14	68788728	3'UTR	novel		0.52
UCEC	chr14	68788836	Intron	novel		0.11
UCEC	chr14	68788785	3'UTR	novel		0.29
UCEC	chr14	68790014	Missense_Mutation	novel	A179D	0.29
UCEC	chr14	68789728	Silent	rs773937725	P274P	0.31
UCEC	chr14	68787944	3'Flank	novel		0.44
UCEC	chr14	68789868	Missense_Mutation	novel	P228S	0.09
UCEC	chr14	68788492	3'Flank	novel		0.4
UCEC	chr14	68788593	3'Flank	novel		0.5
UCEC	chr14	68790025	Missense_Mutation	novel	F175L	0.08	zf-CCCH
UCEC	chr14	68790308	Frame_Shift_Del	NA	*S81Cfs67**	0.33
UCEC	chr14	68788593	3'Flank	novel		0.28
UCEC	chr14	68789738	Frame_Shift_Del	NA	*G271Vfs36**	0.28
UCEC	chr14	68788326	3'Flank	novel		0.33
UCEC	chr14	68788618	3'UTR	novel		0.44
UCEC	chr14	68788506	3'Flank	novel		0.28
UCEC	chr14	68788618	3'UTR	novel		0.36
UCEC	chr14	68789074	Intron	novel		0.37
UCEC	chr14	68788635	3'UTR	novel		0.14
UCEC	chr14	68788618	3'UTR	novel		0.38
UCEC	chr14	68788071	3'Flank	novel		0.33
UCEC	chr14	68790168	Missense_Mutation	novel	A128T	0.44
UCEC	chr14	68789368	Intron	novel		0.23
UCEC	chr14	68790085	Silent	novel	T155T	0.47
UCEC	chr14	68796240	5'Flank	novel		0.46
UCEC	chr14	68790386	Missense_Mutation	novel	V55D	0.44
UCEC	chr14	68789738	Frame_Shift_Del	NA	*G271Vfs36**	0.26
UCEC	chr14	68788326	3'Flank	novel		0.82
UCEC	chr14	68787829	3'Flank	novel		0.36
UCEC	chr14	68790145	Nonsense_Mutation	novel	C135*	0.32
UCEC	chr14	68789947	Missense_Mutation	novel	S201R	0.45
UCEC	chr14	68788617	3'UTR	novel		0.38
UCEC	chr14	68790266	Frame_Shift_Del	novel	*G95Afs53**	0.19
UCEC	chr14	68795089	5'Flank	novel		0.4
UCEC	chr14	68789738	Frame_Shift_Del	NA	*G271Vfs36**	0.4
UCEC	chr14	68796203	5'Flank	novel		0.46
UCEC	chr14	68789433	Intron	novel		0.31
UCEC	chr14	68795207	5'Flank	novel		0.17
UCEC	chr14	68792940	5'UTR	novel		0.19
UCEC	chr14	68789671	Frame_Shift_Del	NA	*S294Afs13**	0.08
UCEC	chr14	68787942	3'Flank	novel		0.49
UCEC	chr14	68788625	3'UTR	novel		0.38
UCEC	chr14	68789719	Silent	NA	F277F	0.23
UCEC	chr14	68790215	Missense_Mutation	novel	S112F	0.38
UCEC	chr14	68790324	Missense_Mutation	novel	A76S	0.26
UCEC	chr14	68788622	3'UTR	novel		0.55
UCEC	chr14	68790141	Missense_Mutation	novel	F137L	0.48
UCEC	chr14	68787901	3'Flank	novel		0.43
UCEC	chr14	68787688	3'Flank	novel		0.45
UCEC	chr14	68789382	Intron	novel		0.15
UCEC	chr14	68788697	3'UTR	novel		0.44
UCEC	chr14	68787812	3'Flank	novel		0.43
UCEC	chr14	68789852	Missense_Mutation	novel	S233N	0.35
UCS	chr14	68790329	Frame_Shift_Del	novel	*N65Sfs6**	0.44
UCS	chr14	68789579	Nonsense_Mutation	NA	S324*	0.54

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	DEL	0.1444	0.19769
BLCA	DEL	0.2647	1.3074e-08
BRCA	DEL	0.2722	1.4717e-06
CESC	DEL	0.1051	0.00086239
CHOL	DEL	0.5556	0.00040262
COAD	DEL	0.2882	0.050084
GBM	DEL	0.2721	5.7274e-07
HNSC	DEL	0.092	0.0057325
KIRC	DEL	0.3807	0.0074281
KIRP	DEL	0.1667	0.085174
LGG	DEL	0.2047	1.1681e-13
LIHC	DEL	0.3135	8.4799e-08
LUAD	DEL	0.2016	0.0018747
LUSC	AMP	0.1756	0.064655
MESO	DEL	0.4023	0.088547
OV	AMP	0.095	0.0046435
OV	DEL	0.4698	6.0694e-08
PAAD	DEL	0.0652	0.11332
READ	DEL	0.3576	0.189
SARC	DEL	0.2879	0.0013077
SKCM	DEL	0.2779	0.10277
STAD	DEL	0.2132	0.0031145

Survival Analysis

Cancer	P-value	Q-value
THYM	0.0026	Kaplan-Meier Survival Analysis
UCS	0.0012	Kaplan-Meier Survival Analysis
KIRP	0.0049	Kaplan-Meier Survival Analysis
COAD	0.034	Kaplan-Meier Survival Analysis
PAAD	0.0037	Kaplan-Meier Survival Analysis
PCPG	0.033	Kaplan-Meier Survival Analysis
GBM	0.021	Kaplan-Meier Survival Analysis
LIHC	0.024	Kaplan-Meier Survival Analysis
LGG	0.00034	Kaplan-Meier Survival Analysis
CHOL	0.04	Kaplan-Meier Survival Analysis
OV	0.0028	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000185650 (Gene tree)
Gene ID: 677
Gene Symbol: ZFP36L1
Alias: RNF162B|Berg36|ERF1|TIS11B|cMG1|BRF1
Full Name: ZFP36 ring finger protein like 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 8,599 bases
Position: chr14:68,787,655-68,796,253
Accession: 1107
RBP type: canonical RBP
Summary: This gene is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000450600	zf-CCCH	PF00642.24	9.2e-23	1	2
ENSP00000450600	zf-CCCH	PF00642.24	9.2e-23	2	2
ENSP00000450784	zf-CCCH	PF00642.24	1.5e-22	1	2
ENSP00000450784	zf-CCCH	PF00642.24	1.5e-22	2	2
ENSP00000337386	zf-CCCH	PF00642.24	5.6e-22	1	2
ENSP00000337386	zf-CCCH	PF00642.24	5.6e-22	2	2
ENSP00000388402	zf-CCCH	PF00642.24	5.6e-22	1	2
ENSP00000388402	zf-CCCH	PF00642.24	5.6e-22	2	2

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
16306087	Antagonistic functions of tetradecanoyl phorbol acetate-inducible-sequence 11b and HuR in the hormonal regulation of vascular endothelial growth factor messenger ribonucleic acid stability by adrenocorticotropin.	Mol Endocrinol	2006 Apr	Cherradi N	-
23423171	Ovarian regulation of neuromedin U and its local actions in the ovary, mediated through neuromedin U receptor 2.	Am J Physiol Endocrinol Metab	2013 Apr 15	Lin TY	doi: 10.1152/ajpendo.00548.2012
30962286	AU-rich element-mediated mRNA decay via the butyrate response factor 1 controls cellular levels of polyadenylated replication-dependent histone mRNAs.	J Biol Chem	2019 May 10	Ryu I	doi: 10.1074/jbc.AC118.006766
15226444	Chorioallantoic fusion defects and embryonic lethality resulting from disruption of Zfp36L1, a gene encoding a CCCH tandem zinc finger protein of the Tristetraprolin family.	Mol Cell Biol	2004 Jul	Stumpo DJ	-
11796723	Members of the tristetraprolin family of tandem CCCH zinc finger proteins exhibit CRM1-dependent nucleocytoplasmic shuttling.	J Biol Chem	2002 Mar 29	Phillips RS	-
19801654	Von Hippel-Lindau gene product modulates TIS11B expression in renal cell carcinoma: impact on vascular endothelial growth factor expression in hypoxia.	J Biol Chem	2009 Nov 20	Sinha S	doi: 10.1074/jbc.M109.058065
18419273	Biological clocks and the coordination theory of RNA operons and regulons.	Cold Spring Harb Symp Quant Biol	2007	Keene JD	doi: 10.1101/sqb.2007.72.013.
17013884	The RNA binding protein Zfp36l1 is required for normal vascularisation and post-transcriptionally regulates VEGF expression.	Dev Dyn	2006 Nov	Bell SE	-
23266986	Involvement of XZFP36L1, an RNA-binding protein, in Xenopus neural development.	Dongwuxue Yanjiu	2012 Dec	Xia YJ	doi: 10.3724/SP.J.1141.2012.E05-06E82.
21278925	The roles of TTP and BRF proteins in regulated mRNA decay.	Wiley Interdiscip Rev RNA	2011 Jan-Feb	Sanduja S	doi: 10.1002/wrna.28.
20622884	Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia.	Nat Immunol	2010 Aug	Hodson DJ	doi: 10.1038/ni.1901
25014217	Post-transcriptional regulation of BCL2 mRNA by the RNA-binding protein ZFP36L1 in malignant B cells.	PLoS One	2014 Jul 11	Zekavati A	doi: 10.1371/journal.pone.0102625
27708140	The cAMP pathway regulates mRNA decay through phosphorylation of the RNA-binding protein TIS11b/BRF1.	Mol Biol Cell	2016 Dec 1	Rataj F	-
27102483	RNA-binding proteins ZFP36L1 and ZFP36L2 promote cell quiescence.	Science	2016 Apr 22	Galloway A	doi: 10.1126/science.aad5978.
27566829	The RNA-Binding Proteins Zfp36l1 and Zfp36l2 Enforce the Thymic β-Selection Checkpoint by Limiting DNA Damage Response Signaling and Cell Cycle Progression.	J Immunol	2016 Oct 1	Vogel KU	doi: 10.4049/jimmunol.1600854
26280535	mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype.	Nat Cell Biol	2015 Sep	Herranz N	doi: 10.1038/ncb3225
28394372	Maintenance of the marginal-zone B cell compartment specifically requires the RNA-binding protein ZFP36L1.	Nat Immunol	2017 Jun	Newman R	doi: 10.1038/ni.3724
28891815	RNA-binding protein ZFP36L1 maintains posttranscriptional regulation of bile acid metabolism.	J Clin Invest	2017 Oct 2	Tarling EJ	doi: 10.1172/JCI94029
29880481	Reciprocal Regulation of DUSP9 and DUSP16 Expression by HIF1 Controls ERK and p38 MAP Kinase Activity and Mediates Chemotherapy-Induced Breast Cancer Stem Cell Enrichment.	Cancer Res	2018 Aug 1	Lu H	doi: 10.1158/0008-5472.CAN-18-0270
30449617	A Membraneless Organelle Associated with the Endoplasmic Reticulum Enables 3'UTR-Mediated Protein-Protein Interactions.	Cell	2018 Nov 29	Ma W	doi: 10.1016/j.cell.2018.10.007
30526691	The RNA-binding proteins Zfp36l1 and Zfp36l2 act redundantly in myogenesis.	Skelet Muscle	2018 Dec 7	Bye-A-Jee H	doi: 10.1186/s13395-018-0183-9.
30622281	RNA-binding protein ZFP36L1 regulates osteoarthritis by modulating members of the heat shock protein 70 family.	Nat Commun	2019 Jan 8	Son YO	doi: 10.1038/s41467-018-08035-7.

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000557022	ZFP36L1-205	577	-	ENSP00000450600	176 (aa)	-	G3V2D5
ENST00000557086	ZFP36L1-206	727	-	ENSP00000450784	207 (aa)	-	G3V2P5
ENST00000439696	ZFP36L1-202	3190	-	ENSP00000388402	338 (aa)	-	Q07352
ENST00000336440	ZFP36L1-201	3026	-	ENSP00000337386	338 (aa)	-	Q07352
ENST00000555997	ZFP36L1-204	3094	-	ENSP00000451093	69 (aa)	-	G3V382
ENST00000553375	ZFP36L1-203	633	-	ENSP00000452119	189 (aa)	-	G3V515

Gene Model

Click here to download ENSG00000185650's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa04218	Cellular senescence	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000185650	Platelet Function Tests	1.2086900E-005	-
ENSG00000185650	Age-Related Hearing Impairment 1	8E-9	24939585
ENSG00000185650	Inflammatory Bowel Diseases	1E-8	26192919
ENSG00000185650	Diabetes Mellitus, Type 1	2E-12	19430480
ENSG00000185650	Fibrinogen	1E-8	23969696
ENSG00000185650	Fibrinogen	4E-13	28107422
ENSG00000185650	Inflammatory Bowel Diseases	3E-10	23128233
ENSG00000185650	Crohn Disease	1E-7	26192919
ENSG00000185650	Fibrinogen	8E-14	28107422
ENSG00000185650	Fibrinogen	2E-12	26561523
ENSG00000185650	Celiac Disease	4E-7	20190752
ENSG00000185650	Multiple Sclerosis	9E-12	21833088

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000185650	rs2236262	14	68794755	A	Multiple sclerosis	24076602		1.08	EFO_0003885
ENSG00000185650	rs11851414	14	68792785	?	Celiac disease	22057235		1.13	EFO_0001060
ENSG00000185650	rs3825568	14	68793871	?	Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular)	23603761	[1.19-1.43]	1.2987013	EFO_1001999\|EFO_1002020\|EFO_1002019
ENSG00000185650	rs57786342	14	68793311	G	Macrophage inflammatory protein 1a levels	27989323	[0.076-0.187] SD units decrease	0.1314	EFO_0008218
ENSG00000185650	rs12889006	14	68793846	?	Respiratory diseases	30595370			EFO_0000684
ENSG00000185650	rs927292	14	68792124	?	Red cell distribution width	30595370			EFO_0005192
ENSG00000185650	rs2236262	14	68794755	?	Systolic blood pressure	30595370			EFO_0006335
ENSG00000185650	rs57786342	14	68793311	G	Diastolic blood pressure	30224653	[0.1-0.185] mmHg decrease	0.1423	EFO_0006336

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000185650's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000185650	ZFP36L1	60	75.893	ENSG00000152518	ZFP36L2	75	60.241

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000185650	ZFP36L1	71	36.877	ENSAPOG00000014920	zgc:162730	68	36.545	Acanthochromis_polyacanthus
ENSG00000185650	ZFP36L1	90	68.391	ENSAPOG00000020931	zfp36l1a	100	58.205	Acanthochromis_polyacanthus
ENSG00000185650	ZFP36L1	67	39.286	ENSAPOG00000014912	zgc:114130	64	38.869	Acanthochromis_polyacanthus
ENSG00000185650	ZFP36L1	100	98.817	ENSAMEG00000014353	ZFP36L1	100	98.817	Ailuropoda_melanoleuca
ENSG00000185650	ZFP36L1	99	62.371	ENSACIG00000016314	zfp36l1a	100	59.621	Amphilophus_citrinellus
ENSG00000185650	ZFP36L1	67	45.594	ENSACIG00000009027	sb:cb81	62	45.420	Amphilophus_citrinellus
ENSG00000185650	ZFP36L1	90	68.208	ENSAOCG00000019239	zfp36l1a	100	58.098	Amphiprion_ocellaris
ENSG00000185650	ZFP36L1	71	36.545	ENSAOCG00000002001	zgc:162730	68	36.545	Amphiprion_ocellaris
ENSG00000185650	ZFP36L1	90	68.208	ENSAPEG00000010246	zfp36l1a	100	58.098	Amphiprion_percula
ENSG00000185650	ZFP36L1	71	36.545	ENSAPEG00000015490	zgc:162730	71	36.545	Amphiprion_percula
ENSG00000185650	ZFP36L1	71	43.066	ENSATEG00000003462	sb:cb81	64	42.909	Anabas_testudineus
ENSG00000185650	ZFP36L1	90	68.208	ENSATEG00000004546	zfp36l1a	100	57.841	Anabas_testudineus
ENSG00000185650	ZFP36L1	99	66.845	ENSATEG00000014086	zfp36l1b	100	57.784	Anabas_testudineus
ENSG00000185650	ZFP36L1	100	99.408	ENSANAG00000037142	ZFP36L1	100	99.408	Aotus_nancymaae
ENSG00000185650	ZFP36L1	67	45.769	ENSACLG00000013759	sb:cb81	62	45.977	Astatotilapia_calliptera
ENSG00000185650	ZFP36L1	90	66.092	ENSACLG00000007768	zfp36l1a	100	56.154	Astatotilapia_calliptera
ENSG00000185650	ZFP36L1	90	72.674	ENSAMXG00000036093	zfp36l1a	99	60.825	Astyanax_mexicanus
ENSG00000185650	ZFP36L1	93	63.158	ENSAMXG00000029887	zfp36l1b	100	53.279	Astyanax_mexicanus
ENSG00000185650	ZFP36L1	93	46.341	ENSAMXG00000034874	sb:cb81	94	41.470	Astyanax_mexicanus
ENSG00000185650	ZFP36L1	67	41.270	ENSAMXG00000035945	zgc:162730	68	41.667	Astyanax_mexicanus
ENSG00000185650	ZFP36L1	67	44.106	ENSAMXG00000038581	zgc:114130	64	45.283	Astyanax_mexicanus
ENSG00000185650	ZFP36L1	100	99.112	ENSBTAG00000025434	ZFP36L1	100	99.112	Bos_taurus
ENSG00000185650	ZFP36L1	100	99.408	ENSCJAG00000042187	ZFP36L1	100	99.408	Callithrix_jacchus
ENSG00000185650	ZFP36L1	100	98.295	ENSCAFG00000016497	ZFP36L1	100	98.225	Canis_familiaris
ENSG00000185650	ZFP36L1	100	98.295	ENSCAFG00020005951	ZFP36L1	100	98.225	Canis_lupus_dingo
ENSG00000185650	ZFP36L1	100	99.112	ENSCHIG00000022716	ZFP36L1	100	99.112	Capra_hircus
ENSG00000185650	ZFP36L1	100	98.225	ENSTSYG00000034276	ZFP36L1	100	98.225	Carlito_syrichta
ENSG00000185650	ZFP36L1	100	97.727	ENSCAPG00000005988	ZFP36L1	98	95.783	Cavia_aperea
ENSG00000185650	ZFP36L1	100	98.521	ENSCPOG00000040127	ZFP36L1	100	98.521	Cavia_porcellus
ENSG00000185650	ZFP36L1	100	99.704	ENSCCAG00000007439	ZFP36L1	100	99.704	Cebus_capucinus
ENSG00000185650	ZFP36L1	100	99.408	ENSCATG00000043529	ZFP36L1	100	99.408	Cercocebus_atys
ENSG00000185650	ZFP36L1	100	98.225	ENSCLAG00000003695	ZFP36L1	100	98.225	Chinchilla_lanigera
ENSG00000185650	ZFP36L1	100	99.704	ENSCSAG00000013114	ZFP36L1	100	99.704	Chlorocebus_sabaeus
ENSG00000185650	ZFP36L1	100	89.266	ENSCPBG00000021516	ZFP36L1	100	86.510	Chrysemys_picta_bellii
ENSG00000185650	ZFP36L1	100	99.704	ENSCANG00000031505	ZFP36L1	100	99.704	Colobus_angolensis_palliatus
ENSG00000185650	ZFP36L1	100	98.817	ENSCGRG00001010926	Zfp36l1	100	98.817	Cricetulus_griseus_chok1gshd
ENSG00000185650	ZFP36L1	100	98.521	ENSCGRG00000007735	Zfp36l1	100	98.521	Cricetulus_griseus_crigri
ENSG00000185650	ZFP36L1	100	56.777	ENSCSEG00000007039	zfp36l1a	100	57.033	Cynoglossus_semilaevis
ENSG00000185650	ZFP36L1	67	43.083	ENSCSEG00000018283	zgc:162730	95	34.234	Cynoglossus_semilaevis
ENSG00000185650	ZFP36L1	99	62.944	ENSCVAG00000008482	zfp36l1a	100	55.897	Cyprinodon_variegatus
ENSG00000185650	ZFP36L1	93	54.645	ENSCVAG00000020132	-	97	46.814	Cyprinodon_variegatus
ENSG00000185650	ZFP36L1	67	43.373	ENSDARG00000103720	zgc:162730	72	44.000	Danio_rerio
ENSG00000185650	ZFP36L1	67	48.148	ENSDARG00000040725	zgc:114130	62	48.178	Danio_rerio
ENSG00000185650	ZFP36L1	86	47.644	ENSDARG00000040503	sb:cb81	90	42.373	Danio_rerio
ENSG00000185650	ZFP36L1	99	64.767	ENSDARG00000016154	zfp36l1a	100	58.763	Danio_rerio
ENSG00000185650	ZFP36L1	98	61.905	ENSDARG00000021443	zfp36l1b	99	58.919	Danio_rerio
ENSG00000185650	ZFP36L1	100	97.159	ENSDNOG00000005159	ZFP36L1	100	98.084	Dasypus_novemcinctus
ENSG00000185650	ZFP36L1	100	98.817	ENSDORG00000029853	Zfp36l1	100	98.817	Dipodomys_ordii
ENSG00000185650	ZFP36L1	100	98.817	ENSEASG00005008760	ZFP36L1	100	98.817	Equus_asinus_asinus
ENSG00000185650	ZFP36L1	100	98.817	ENSECAG00000018860	ZFP36L1	100	98.817	Equus_caballus
ENSG00000185650	ZFP36L1	97	39.276	ENSELUG00000013151	zgc:114130	95	39.276	Esox_lucius
ENSG00000185650	ZFP36L1	67	43.307	ENSELUG00000013158	zgc:162730	68	43.307	Esox_lucius
ENSG00000185650	ZFP36L1	99	57.320	ENSELUG00000021506	zfp36l1a	99	58.025	Esox_lucius
ENSG00000185650	ZFP36L1	67	48.498	ENSELUG00000013045	sb:cb81	63	48.069	Esox_lucius
ENSG00000185650	ZFP36L1	94	67.213	ENSELUG00000008675	zfp36l1b	100	59.126	Esox_lucius
ENSG00000185650	ZFP36L1	100	99.112	ENSFCAG00000026617	ZFP36L1	100	99.112	Felis_catus
ENSG00000185650	ZFP36L1	100	89.266	ENSFALG00000015146	ZFP36L1	100	87.812	Ficedula_albicollis
ENSG00000185650	ZFP36L1	100	98.225	ENSFDAG00000014938	ZFP36L1	100	98.225	Fukomys_damarensis
ENSG00000185650	ZFP36L1	90	68.786	ENSFHEG00000001313	zfp36l1a	100	55.928	Fundulus_heteroclitus
ENSG00000185650	ZFP36L1	67	47.126	ENSFHEG00000022187	sb:cb81	62	47.710	Fundulus_heteroclitus
ENSG00000185650	ZFP36L1	57	59.000	ENSGMOG00000006664	zfp36l1b	50	60.000	Gadus_morhua
ENSG00000185650	ZFP36L1	100	88.136	ENSGALG00000039228	ZFP36L1	100	86.510	Gallus_gallus
ENSG00000185650	ZFP36L1	97	43.684	ENSGAFG00000015700	sb:cb81	98	43.307	Gambusia_affinis
ENSG00000185650	ZFP36L1	88	68.023	ENSGAFG00000018711	zfp36l1a	100	55.216	Gambusia_affinis
ENSG00000185650	ZFP36L1	97	64.583	ENSGACG00000011271	zfp36l1a	99	58.808	Gasterosteus_aculeatus
ENSG00000185650	ZFP36L1	100	89.831	ENSGAGG00000007315	ZFP36L1	100	86.510	Gopherus_agassizii
ENSG00000185650	ZFP36L1	100	100.000	ENSGGOG00000041615	ZFP36L1	100	100.000	Gorilla_gorilla
ENSG00000185650	ZFP36L1	67	45.769	ENSHBUG00000002383	sb:cb81	61	45.594	Haplochromis_burtoni
ENSG00000185650	ZFP36L1	90	66.092	ENSHBUG00000016051	zfp36l1a	100	56.154	Haplochromis_burtoni
ENSG00000185650	ZFP36L1	100	98.521	ENSHGLG00000016491	ZFP36L1	100	98.521	Heterocephalus_glaber_female
ENSG00000185650	ZFP36L1	100	98.521	ENSHGLG00100018163	ZFP36L1	100	98.521	Heterocephalus_glaber_male
ENSG00000185650	ZFP36L1	100	60.104	ENSHCOG00000013932	zfp36l1a	100	60.104	Hippocampus_comes
ENSG00000185650	ZFP36L1	57	55.882	ENSHCOG00000012747	zfp36l1b	92	55.882	Hippocampus_comes
ENSG00000185650	ZFP36L1	67	42.366	ENSIPUG00000018248	zgc:162730	70	42.748	Ictalurus_punctatus
ENSG00000185650	ZFP36L1	99	67.708	ENSIPUG00000023681	ZFP36L1	99	60.104	Ictalurus_punctatus
ENSG00000185650	ZFP36L1	97	39.323	ENSIPUG00000011378	sb:cb81	98	41.842	Ictalurus_punctatus
ENSG00000185650	ZFP36L1	66	43.038	ENSIPUG00000018256	zgc:114130	53	45.188	Ictalurus_punctatus
ENSG00000185650	ZFP36L1	100	99.408	ENSSTOG00000009758	ZFP36L1	100	99.408	Ictidomys_tridecemlineatus
ENSG00000185650	ZFP36L1	100	97.159	ENSJJAG00000017247	Zfp36l1	91	98.077	Jaculus_jaculus
ENSG00000185650	ZFP36L1	90	68.786	ENSKMAG00000013156	zfp36l1a	100	56.812	Kryptolebias_marmoratus
ENSG00000185650	ZFP36L1	67	41.696	ENSLBEG00000018387	zgc:114130	65	42.199	Labrus_bergylta
ENSG00000185650	ZFP36L1	99	63.542	ENSLBEG00000008102	zfp36l1a	89	60.511	Labrus_bergylta
ENSG00000185650	ZFP36L1	100	65.278	ENSLACG00000015967	ZFP36L1	100	65.556	Latimeria_chalumnae
ENSG00000185650	ZFP36L1	81	44.693	ENSLACG00000015980	-	92	38.504	Latimeria_chalumnae
ENSG00000185650	ZFP36L1	68	51.230	ENSLACG00000015732	sb:cb81	98	42.507	Latimeria_chalumnae
ENSG00000185650	ZFP36L1	99	50.498	ENSLACG00000012879	-	99	51.244	Latimeria_chalumnae
ENSG00000185650	ZFP36L1	100	45.667	ENSLOCG00000016446	-	97	45.667	Lepisosteus_oculatus
ENSG00000185650	ZFP36L1	67	41.313	ENSLOCG00000014597	zgc:162730	86	37.920	Lepisosteus_oculatus
ENSG00000185650	ZFP36L1	96	72.376	ENSLOCG00000013957	zfp36l1a	100	65.600	Lepisosteus_oculatus
ENSG00000185650	ZFP36L1	70	46.442	ENSLOCG00000014587	sb:cb81	66	46.237	Lepisosteus_oculatus
ENSG00000185650	ZFP36L1	100	98.864	ENSLAFG00000028594	ZFP36L1	100	98.521	Loxodonta_africana
ENSG00000185650	ZFP36L1	100	99.704	ENSMFAG00000033125	ZFP36L1	100	99.704	Macaca_fascicularis
ENSG00000185650	ZFP36L1	100	99.704	ENSMMUG00000044603	ZFP36L1	100	99.704	Macaca_mulatta
ENSG00000185650	ZFP36L1	100	99.432	ENSMNEG00000032614	ZFP36L1	100	97.929	Macaca_nemestrina
ENSG00000185650	ZFP36L1	100	99.408	ENSMLEG00000044247	ZFP36L1	100	99.408	Mandrillus_leucophaeus
ENSG00000185650	ZFP36L1	90	68.235	ENSMAMG00000000274	zfp36l1a	88	58.901	Mastacembelus_armatus
ENSG00000185650	ZFP36L1	90	66.092	ENSMZEG00005014679	zfp36l1a	100	56.154	Maylandia_zebra
ENSG00000185650	ZFP36L1	67	46.332	ENSMZEG00005016001	-	61	45.594	Maylandia_zebra
ENSG00000185650	ZFP36L1	67	46.304	ENSMZEG00005024684	sb:cb81	61	46.512	Maylandia_zebra
ENSG00000185650	ZFP36L1	100	98.817	ENSMAUG00000020087	Zfp36l1	100	98.817	Mesocricetus_auratus
ENSG00000185650	ZFP36L1	100	99.112	ENSMICG00000037296	ZFP36L1	100	99.112	Microcebus_murinus
ENSG00000185650	ZFP36L1	100	98.521	ENSMOCG00000003189	Zfp36l1	100	98.521	Microtus_ochrogaster
ENSG00000185650	ZFP36L1	90	68.786	ENSMMOG00000011231	zfp36l1a	99	58.140	Mola_mola
ENSG00000185650	ZFP36L1	67	43.939	ENSMMOG00000010073	sb:cb81	66	45.382	Mola_mola
ENSG00000185650	ZFP36L1	100	84.956	ENSMODG00000010122	ZFP36L1	100	84.071	Monodelphis_domestica
ENSG00000185650	ZFP36L1	91	67.429	ENSMALG00000021238	zfp36l1a	100	58.639	Monopterus_albus
ENSG00000185650	ZFP36L1	94	66.292	ENSMALG00000016768	zfp36l1b	100	52.770	Monopterus_albus
ENSG00000185650	ZFP36L1	100	98.521	MGP_CAROLIEiJ_G0017893	Zfp36l1	100	98.521	Mus_caroli
ENSG00000185650	ZFP36L1	100	98.521	ENSMUSG00000021127	Zfp36l1	100	98.521	Mus_musculus
ENSG00000185650	ZFP36L1	100	98.521	MGP_PahariEiJ_G0029649	Zfp36l1	100	98.521	Mus_pahari
ENSG00000185650	ZFP36L1	100	98.521	MGP_SPRETEiJ_G0018738	Zfp36l1	100	98.521	Mus_spretus
ENSG00000185650	ZFP36L1	100	92.308	ENSMPUG00000007282	ZFP36L1	100	92.308	Mustela_putorius_furo
ENSG00000185650	ZFP36L1	100	98.817	ENSNGAG00000024367	Zfp36l1	100	98.817	Nannospalax_galili
ENSG00000185650	ZFP36L1	86	40.741	ENSNBRG00000006231	sb:cb81	89	41.643	Neolamprologus_brichardi
ENSG00000185650	ZFP36L1	100	56.410	ENSNBRG00000010827	zfp36l1a	100	56.154	Neolamprologus_brichardi
ENSG00000185650	ZFP36L1	100	100.000	ENSNLEG00000001046	ZFP36L1	100	99.704	Nomascus_leucogenys
ENSG00000185650	ZFP36L1	100	94.915	ENSMEUG00000003070	ZFP36L1	100	94.690	Notamacropus_eugenii
ENSG00000185650	ZFP36L1	100	98.521	ENSODEG00000014162	ZFP36L1	100	98.521	Octodon_degus
ENSG00000185650	ZFP36L1	100	58.090	ENSONIG00000000973	zfp36l1a	100	57.825	Oreochromis_niloticus
ENSG00000185650	ZFP36L1	67	44.358	ENSONIG00000001259	sb:cb81	61	44.788	Oreochromis_niloticus
ENSG00000185650	ZFP36L1	100	96.450	ENSOCUG00000003168	ZFP36L1	100	96.450	Oryctolagus_cuniculus
ENSG00000185650	ZFP36L1	67	45.736	ENSORLG00000024026	sb:cb81	84	39.163	Oryzias_latipes
ENSG00000185650	ZFP36L1	90	69.006	ENSORLG00000029605	zfp36l1a	100	58.486	Oryzias_latipes
ENSG00000185650	ZFP36L1	99	64.398	ENSORLG00020021609	zfp36l1a	100	58.793	Oryzias_latipes_hni
ENSG00000185650	ZFP36L1	90	69.006	ENSORLG00015019460	zfp36l1a	100	58.486	Oryzias_latipes_hsok
ENSG00000185650	ZFP36L1	90	68.571	ENSOMEG00000018296	zfp36l1a	100	58.140	Oryzias_melastigma
ENSG00000185650	ZFP36L1	51	67.778	ENSOMEG00000017752	zgc:162730	67	39.024	Oryzias_melastigma
ENSG00000185650	ZFP36L1	93	57.222	ENSOMEG00000001264	-	97	47.277	Oryzias_melastigma
ENSG00000185650	ZFP36L1	100	97.929	ENSOGAG00000010033	ZFP36L1	100	97.929	Otolemur_garnettii
ENSG00000185650	ZFP36L1	100	82.840	ENSOARG00000021177	ZFP36L1	100	82.840	Ovis_aries
ENSG00000185650	ZFP36L1	100	99.704	ENSPPAG00000027452	ZFP36L1	100	99.704	Pan_paniscus
ENSG00000185650	ZFP36L1	100	99.112	ENSPPRG00000015094	ZFP36L1	100	99.112	Panthera_pardus
ENSG00000185650	ZFP36L1	100	86.686	ENSPTIG00000019155	ZFP36L1	100	86.686	Panthera_tigris_altaica
ENSG00000185650	ZFP36L1	100	99.704	ENSPTRG00000051193	ZFP36L1	100	99.704	Pan_troglodytes
ENSG00000185650	ZFP36L1	100	99.704	ENSPANG00000009731	ZFP36L1	100	99.704	Papio_anubis
ENSG00000185650	ZFP36L1	94	71.429	ENSPKIG00000009504	-	100	61.538	Paramormyrops_kingsleyae
ENSG00000185650	ZFP36L1	99	69.312	ENSPKIG00000007298	ZFP36L1	100	60.950	Paramormyrops_kingsleyae
ENSG00000185650	ZFP36L1	100	89.831	ENSPSIG00000008151	ZFP36L1	100	88.270	Pelodiscus_sinensis
ENSG00000185650	ZFP36L1	67	47.521	ENSPMGG00000009232	sb:cb81	79	47.521	Periophthalmus_magnuspinnatus
ENSG00000185650	ZFP36L1	100	62.117	ENSPMGG00000000442	zfp36l1a	100	61.838	Periophthalmus_magnuspinnatus
ENSG00000185650	ZFP36L1	50	64.865	ENSPMGG00000011911	zgc:162730	58	62.500	Periophthalmus_magnuspinnatus
ENSG00000185650	ZFP36L1	100	98.521	ENSPEMG00000011361	Zfp36l1	100	98.521	Peromyscus_maniculatus_bairdii
ENSG00000185650	ZFP36L1	100	94.395	ENSPCIG00000019895	ZFP36L1	88	94.395	Phascolarctos_cinereus
ENSG00000185650	ZFP36L1	97	41.995	ENSPFOG00000013806	sb:cb81	98	42.147	Poecilia_formosa
ENSG00000185650	ZFP36L1	90	66.480	ENSPFOG00000017436	zfp36l1a	100	54.684	Poecilia_formosa
ENSG00000185650	ZFP36L1	90	68.235	ENSPLAG00000005641	zfp36l1a	100	55.065	Poecilia_latipinna
ENSG00000185650	ZFP36L1	79	54.217	ENSPLAG00000020158	sb:cb81	96	44.543	Poecilia_latipinna
ENSG00000185650	ZFP36L1	90	66.480	ENSPMEG00000013028	zfp36l1a	100	54.822	Poecilia_mexicana
ENSG00000185650	ZFP36L1	81	84.211	ENSPMEG00000022425	sb:cb81	98	42.147	Poecilia_mexicana
ENSG00000185650	ZFP36L1	90	68.639	ENSPREG00000013484	zfp36l1a	100	55.729	Poecilia_reticulata
ENSG00000185650	ZFP36L1	97	40.104	ENSPREG00000017495	sb:cb81	98	41.470	Poecilia_reticulata
ENSG00000185650	ZFP36L1	100	99.704	ENSPPYG00000005933	ZFP36L1	100	99.704	Pongo_abelii
ENSG00000185650	ZFP36L1	100	99.112	ENSPCAG00000005383	ZFP36L1	100	99.112	Procavia_capensis
ENSG00000185650	ZFP36L1	100	98.864	ENSPCOG00000022518	ZFP36L1	100	98.817	Propithecus_coquereli
ENSG00000185650	ZFP36L1	100	97.159	ENSPVAG00000011686	ZFP36L1	100	97.806	Pteropus_vampyrus
ENSG00000185650	ZFP36L1	90	66.092	ENSPNYG00000004953	zfp36l1a	100	56.154	Pundamilia_nyererei
ENSG00000185650	ZFP36L1	86	40.336	ENSPNYG00000007502	sb:cb81	98	39.798	Pundamilia_nyererei
ENSG00000185650	ZFP36L1	90	41.000	ENSPNAG00000023029	zgc:114130	65	42.125	Pygocentrus_nattereri
ENSG00000185650	ZFP36L1	97	42.199	ENSPNAG00000030063	sb:cb81	94	43.324	Pygocentrus_nattereri
ENSG00000185650	ZFP36L1	96	64.773	ENSPNAG00000000386	zfp36l1b	98	56.620	Pygocentrus_nattereri
ENSG00000185650	ZFP36L1	67	42.975	ENSPNAG00000023018	zgc:162730	69	42.975	Pygocentrus_nattereri
ENSG00000185650	ZFP36L1	94	69.231	ENSPNAG00000015712	zfp36l1a	99	60.363	Pygocentrus_nattereri
ENSG00000185650	ZFP36L1	100	98.521	ENSRNOG00000058646	Zfp36l1	100	98.521	Rattus_norvegicus
ENSG00000185650	ZFP36L1	100	99.432	ENSRBIG00000040496	-	98	98.758	Rhinopithecus_bieti
ENSG00000185650	ZFP36L1	100	99.704	ENSRROG00000040595	ZFP36L1	100	99.704	Rhinopithecus_roxellana
ENSG00000185650	ZFP36L1	100	99.704	ENSSBOG00000025671	ZFP36L1	100	99.704	Saimiri_boliviensis_boliviensis
ENSG00000185650	ZFP36L1	100	94.915	ENSSHAG00000011647	ZFP36L1	100	94.395	Sarcophilus_harrisii
ENSG00000185650	ZFP36L1	96	69.444	ENSSFOG00015002575	-	99	59.200	Scleropages_formosus
ENSG00000185650	ZFP36L1	96	66.129	ENSSFOG00015020649	ZFP36L1	100	61.433	Scleropages_formosus
ENSG00000185650	ZFP36L1	67	38.866	ENSSFOG00015003179	sb:cb81	98	34.257	Scleropages_formosus
ENSG00000185650	ZFP36L1	90	66.286	ENSSMAG00000012821	zfp36l1a	65	55.416	Scophthalmus_maximus
ENSG00000185650	ZFP36L1	83	63.226	ENSSMAG00000018208	-	98	50.314	Scophthalmus_maximus
ENSG00000185650	ZFP36L1	93	66.102	ENSSDUG00000001019	zfp36l1b	99	55.914	Seriola_dumerili
ENSG00000185650	ZFP36L1	90	68.208	ENSSDUG00000009669	zfp36l1a	100	57.841	Seriola_dumerili
ENSG00000185650	ZFP36L1	90	68.208	ENSSLDG00000021382	zfp36l1a	100	57.841	Seriola_lalandi_dorsalis
ENSG00000185650	ZFP36L1	100	55.556	ENSSLDG00000011048	zfp36l1b	99	54.447	Seriola_lalandi_dorsalis
ENSG00000185650	ZFP36L1	100	87.006	ENSSPUG00000002037	ZFP36L1	100	86.510	Sphenodon_punctatus
ENSG00000185650	ZFP36L1	90	68.208	ENSSPAG00000010371	zfp36l1a	100	58.355	Stegastes_partitus
ENSG00000185650	ZFP36L1	71	35.880	ENSSPAG00000006851	zgc:162730	68	36.213	Stegastes_partitus
ENSG00000185650	ZFP36L1	100	99.408	ENSSSCG00000028304	ZFP36L1	100	99.408	Sus_scrofa
ENSG00000185650	ZFP36L1	77	81.439	ENSTGUG00000011494	ZFP36L1	100	81.439	Taeniopygia_guttata
ENSG00000185650	ZFP36L1	90	68.208	ENSTRUG00000022418	zfp36l1	100	57.841	Takifugu_rubripes
ENSG00000185650	ZFP36L1	97	39.055	ENSTRUG00000020720	sb:cb81	98	40.547	Takifugu_rubripes
ENSG00000185650	ZFP36L1	99	60.615	ENSTNIG00000002277	zfp36l1a	100	60.615	Tetraodon_nigroviridis
ENSG00000185650	ZFP36L1	70	39.223	ENSTNIG00000000183	zgc:162730	71	39.100	Tetraodon_nigroviridis
ENSG00000185650	ZFP36L1	67	43.651	ENSTNIG00000019802	sb:cb81	76	46.122	Tetraodon_nigroviridis
ENSG00000185650	ZFP36L1	100	99.112	ENSTTRG00000003475	ZFP36L1	100	99.112	Tursiops_truncatus
ENSG00000185650	ZFP36L1	100	99.112	ENSUAMG00000010751	ZFP36L1	100	99.112	Ursus_americanus
ENSG00000185650	ZFP36L1	100	99.112	ENSUMAG00000010126	ZFP36L1	100	99.112	Ursus_maritimus
ENSG00000185650	ZFP36L1	100	97.929	ENSVVUG00000003551	ZFP36L1	100	97.929	Vulpes_vulpes
ENSG00000185650	ZFP36L1	100	73.770	ENSXETG00000016987	zfp36l1	100	74.148	Xenopus_tropicalis
ENSG00000185650	ZFP36L1	64	52.941	ENSXETG00000023255	zfp36l2.1	63	52.941	Xenopus_tropicalis
ENSG00000185650	ZFP36L1	61	56.322	ENSXETG00000023254	zfp36l2.2	50	60.811	Xenopus_tropicalis
ENSG00000185650	ZFP36L1	81	61.290	ENSXCOG00000010688	sb:cb81	86	42.411	Xiphophorus_couchianus
ENSG00000185650	ZFP36L1	88	69.186	ENSXCOG00000001799	zfp36l1a	100	55.102	Xiphophorus_couchianus
ENSG00000185650	ZFP36L1	97	42.818	ENSXMAG00000004681	sb:cb81	98	42.973	Xiphophorus_maculatus
ENSG00000185650	ZFP36L1	88	68.786	ENSXMAG00000022234	zfp36l1a	100	55.216	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000165	MAPK cascade	18326031.20166898.	IDA	Process
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	-	IEA	Process
GO:0000932	P-body	17369404.	IDA	Component
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	19274049.	ISM	Function
GO:0001570	vasculogenesis	-	IEA	Process
GO:0003342	proepicardium development	-	IEA	Process
GO:0003677	DNA binding	-	IEA	Function
GO:0003700	DNA-binding transcription factor activity	8595910.	NAS	Function
GO:0003723	RNA binding	22658674.	HDA	Function
GO:0003729	mRNA binding	15467755.	IDA	Function
GO:0003730	mRNA 3'-UTR binding	21873635.	IBA	Function
GO:0005515	protein binding	15687258.16189514.18326031.25106868.	IPI	Function
GO:0005634	nucleus	12198173.21832157.	IDA	Component
GO:0005737	cytoplasm	12198173.	IDA	Component
GO:0005829	cytosol	21873635.	IBA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006357	regulation of transcription by RNA polymerase II	-	IEA	Process
GO:0006397	mRNA processing	-	IEA	Process
GO:0006915	apoptotic process	-	IEA	Process
GO:0007507	heart development	-	IEA	Process
GO:0008283	cell proliferation	-	IEA	Process
GO:0009611	response to wounding	27182009.	IDA	Process
GO:0010468	regulation of gene expression	20166898.	IDA	Process
GO:0010837	regulation of keratinocyte proliferation	27182009.	IMP	Process
GO:0014065	phosphatidylinositol 3-kinase signaling	15538381.	IDA	Process
GO:0021915	neural tube development	-	IEA	Process
GO:0031086	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay	-	ISS	Process
GO:0031440	regulation of mRNA 3'-end processing	21832157.	IDA	Process
GO:0032869	cellular response to insulin stimulus	15538381.	IDA	Process
GO:0033077	T cell differentiation in thymus	-	ISS	Process
GO:0035264	multicellular organism growth	-	IEA	Process
GO:0035925	mRNA 3'-UTR AU-rich region binding	12198173.15467755.15538381.18326031.19179481.20702587.21832157.24700863.25014217.25106868.26542173.	IDA	Function
GO:0038066	p38MAPK cascade	-	ISS	Process
GO:0043488	regulation of mRNA stability	15467755.15538381.15687258.18326031.19179481.20702587.24700863.25014217.26542173.	IDA	Process
GO:0043488	regulation of mRNA stability	12198173.25106868.	IMP	Process
GO:0043488	regulation of mRNA stability	-	TAS	Process
GO:0043491	protein kinase B signaling	-	ISS	Process
GO:0044344	cellular response to fibroblast growth factor stimulus	-	ISS	Process
GO:0045577	regulation of B cell differentiation	-	ISS	Process
GO:0045600	positive regulation of fat cell differentiation	-	ISS	Process
GO:0045616	regulation of keratinocyte differentiation	27182009.	IMP	Process
GO:0045647	negative regulation of erythrocyte differentiation	20702587.	IDA	Process
GO:0045657	positive regulation of monocyte differentiation	26542173.	IDA	Process
GO:0045661	regulation of myoblast differentiation	-	ISS	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:0048382	mesendoderm development	-	ISS	Process
GO:0051028	mRNA transport	17369404.	IMP	Process
GO:0060710	chorio-allantoic fusion	-	IEA	Process
GO:0060712	spongiotrophoblast layer development	-	IEA	Process
GO:0061158	3'-UTR-mediated mRNA destabilization	21873635.	IBA	Process
GO:0061158	3'-UTR-mediated mRNA destabilization	15467755.15538381.15687258.18326031.19179481.24700863.26542173.	IDA	Process
GO:0061158	3'-UTR-mediated mRNA destabilization	12198173.25014217.25106868.	IMP	Process
GO:0070371	ERK1 and ERK2 cascade	25106868.	IDA	Process
GO:0071320	cellular response to cAMP	19179481.	IDA	Process
GO:0071356	cellular response to tumor necrosis factor	20166898.	IDA	Process
GO:0071364	cellular response to epidermal growth factor stimulus	20166898.	IDA	Process
GO:0071375	cellular response to peptide hormone stimulus	15467755.19179481.	IDA	Process
GO:0071385	cellular response to glucocorticoid stimulus	20166898.	IDA	Process
GO:0071456	cellular response to hypoxia	21832157.	IMP	Process
GO:0071472	cellular response to salt stress	-	ISS	Process
GO:0071560	cellular response to transforming growth factor beta stimulus	20166898.	IDA	Process
GO:0071889	14-3-3 protein binding	15538381.18326031.	IDA	Function
GO:0072091	regulation of stem cell proliferation	-	ISS	Process
GO:0097403	cellular response to raffinose	-	ISS	Process
GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	-	ISS	Process
GO:1901991	negative regulation of mitotic cell cycle phase transition	-	ISS	Process
GO:1902172	regulation of keratinocyte apoptotic process	27182009.	IMP	Process
GO:1904582	positive regulation of intracellular mRNA localization	17369404.	IMP	Process
GO:1990904	ribonucleoprotein complex	15687258.20702587.21832157.26542173.	IDA	Component

EuRBPDB

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

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GWAS

PPI

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Gene Ontology

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Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.