EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
28178669	ERCC6L, a DNA helicase, is involved in cell proliferation and associated with survival and progress in breast and kidney cancers.	Oncotarget	2017 Jun 27	Pu SY	doi: 10.18632/oncotarget.14998.
30066865	shRNA knockdown of DNA helicase ERCC6L expression inhibits human breast cancer growth.	Mol Med Rep	2018 Sep	Liu J	doi: 10.3892/mmr.2018.9317

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chrX	72206566	Missense_Mutation	novel	P734H	0.27
BLCA	chrX	72206554	Missense_Mutation	novel	S738F	0.29
BLCA	chrX	72208591	Missense_Mutation	novel	R59T	0.23	ResIII
BLCA	chrX	72207811	Missense_Mutation	novel	A319E	0.06
BLCA	chrX	72207314	Missense_Mutation	novel	S485T	0.15
BLCA	chrX	72207605	Missense_Mutation	novel	D388H	0.39
BLCA	chrX	72207953	Missense_Mutation	novel	D272H	0.14
BRCA	chrX	72205008	3'UTR	novel		0.1
BRCA	chrX	72205625	Missense_Mutation	NA	T1048A	0.2
BRCA	chrX	72208419	Missense_Mutation	NA	K116N	0.1	ResIII
BRCA	chrX	72207213	Silent	NA	K518K	0.19
BRCA	chrX	72206184	Silent	NA	P861P	0.16
BRCA	chrX	72205839	Missense_Mutation	NA	E976D	0.39
BRCA	chrX	72207144	Silent	rs781419143	V541V	0.41
BRCA	chrX	72204838	3'UTR	novel		0.17
BRCA	chrX	72205358	Missense_Mutation	rs754122902	E1137K	0.06
BRCA	chrX	72207635	Missense_Mutation	novel	E378K	0.09
BRCA	chrX	72206893	Missense_Mutation	NA	R625T	0.26
BRCA	chrX	72208376	Nonsense_Mutation	novel	Q131*	0.13	ResIII
CESC	chrX	72208088	Missense_Mutation	NA	L227F	0.26
CESC	chrX	72238908	Missense_Mutation	novel	E2K	0.26	ResIII
CESC	chrX	72207036	Missense_Mutation	NA	E577D	0.24
CESC	chrX	72206232	Missense_Mutation	NA	K845N	0.29
CESC	chrX	72207253	Missense_Mutation	NA	R505Q	0.39
CESC	chrX	72207597	Missense_Mutation	NA	I390M	0.18
CESC	chrX	72207531	Silent	novel	D412D	0.47
CESC	chrX	72208012	Missense_Mutation	rs201800132	R252H	0.29
CESC	chrX	72206429	Silent	novel	L780L	0.13
CHOL	chrX	72207833	Missense_Mutation	novel	K312E	0.06
COAD	chrX	72206701	Missense_Mutation	NA	D689V	0.48
COAD	chrX	72205465	Missense_Mutation	NA	N1101I	0.37
COAD	chrX	72207253	Missense_Mutation	NA	R505Q	0.07
COAD	chrX	72207205	Missense_Mutation	novel	N521T	0.05
COAD	chrX	72205530	Missense_Mutation	novel	I1079M	0.06
COAD	chrX	72207771	Silent	rs780525195	D332D	0.27
COAD	chrX	72206132	Missense_Mutation	novel	P879T	0.15
COAD	chrX	72205843	Missense_Mutation	novel	V975G	0.3
COAD	chrX	72205189	Missense_Mutation	novel	A1193V	0.1
COAD	chrX	72204994	3'UTR	novel		0.76
COAD	chrX	72205242	Silent	NA	G1175G	0.71
COAD	chrX	72206572	Missense_Mutation	NA	R732K	0.41
COAD	chrX	72207574	Missense_Mutation	rs139313430	R398H	0.32
COAD	chrX	72206316	Silent	NA	G817G	0.09
DLBC	chrX	72206412	Silent	novel	E785E	0.28
GBM	chrX	72207881	Nonsense_Mutation	novel	R296*	0.08
GBM	chrX	72205992	Silent	novel	H925H	0.15
GBM	chrX	72205498	Missense_Mutation	novel	R1090I	0.04
GBM	chrX	72208657	Missense_Mutation	NA	L37Q	0.28	ResIII
GBM	chrX	72205807	Missense_Mutation	NA	N987S	0.43
GBM	chrX	72205550	Missense_Mutation	novel	R1073W	0.24
GBM	chrX	72206101	Missense_Mutation	novel	I889S	0.24
GBM	chrX	72206754	Silent	novel	I671I	0.32
GBM	chrX	72207178	Missense_Mutation	novel	S530F	0.31
GBM	chrX	72207736	Missense_Mutation	novel	R344I	0.31
GBM	chrX	72207845	Missense_Mutation	novel	A308S	0.06
GBM	chrX	72205089	Silent	NA	A1226A	0.26
HNSC	chrX	72206315	Missense_Mutation	NA	F818V	0.67
HNSC	chrX	72204973	3'UTR	novel		0.9
HNSC	chrX	72205081	Frame_Shift_Ins	novel	*I1229Nfs7**	0.27
HNSC	chrX	72205810	Missense_Mutation	novel	P986R	0.36
HNSC	chrX	72206095	Missense_Mutation	rs146534560	R891H	0.28
HNSC	chrX	72207761	Missense_Mutation	novel	K336E	0.74
KIRC	chrX	72206322	Silent	NA	P815P	0.25
KIRC	chrX	72207735	Silent	NA	R344R	0.21
KIRC	chrX	72208002	Silent	novel	L255L	0.53
KIRP	chrX	72206959	Nonsense_Mutation	NA	S603*	0.07
KIRP	chrX	72207843	Silent	NA	A308A	0.04
LAML	chrX	72207501	Nonsense_Mutation	novel	C422*	0.04
LGG	chrX	72206290	Missense_Mutation	novel	T826I	0.08
LGG	chrX	72207189	Silent	novel	N526N	0.35
LIHC	chrX	72205302	Missense_Mutation	novel	N1155K	0.8
LIHC	chrX	72206464	Missense_Mutation	NA	I768T	0.87
LUAD	chrX	72208611	Silent	novel	P52P	0.16
LUAD	chrX	72206997	Silent	NA	V590V	0.14
LUAD	chrX	72207805	Missense_Mutation	novel	I321T	0.46
LUAD	chrX	72208607	Nonsense_Mutation	NA	E54*	0.28	ResIII
LUAD	chrX	72207340	Frame_Shift_Del	novel	*G476Dfs14**	0.06
LUAD	chrX	72205166	Nonsense_Mutation	NA	E1201*	0.41
LUAD	chrX	72205605	Silent	NA	S1054S	0.72
LUAD	chrX	72205267	Missense_Mutation	novel	A1167D	0.45
LUAD	chrX	72206830	Missense_Mutation	novel	H646P	0.34
LUAD	chrX	72205155	Silent	novel	V1204V	0.16
LUAD	chrX	72205787	Missense_Mutation	novel	H994N	0.12
LUAD	chrX	72206204	Frame_Shift_Ins	novel	*E855Rfs12**	0.14
LUAD	chrX	72207054	Nonsense_Mutation	novel	Y571*	0.1
LUAD	chrX	72205472	Frame_Shift_Del	rs769073969	*I1100Lfs5**	0.49
LUAD	chrX	72205015	Silent	novel	*1251*	0.1
LUAD	chrX	72207456	Silent	NA	E437E	0.05
LUAD	chrX	72205095	Silent	NA	V1224V	0.08
LUSC	chrX	72207807	Silent	NA	I320I	0.45
LUSC	chrX	72206418	Missense_Mutation	novel	E783D	0.59
LUSC	chrX	72206784	Silent	novel	A661A	0.19
LUSC	chrX	72238854	Missense_Mutation	novel	H20Y	0.29	ResIII
LUSC	chrX	72205189	Missense_Mutation	NA	A1193G	0.12
LUSC	chrX	72206103	Missense_Mutation	NA	E888D	0.08
LUSC	chrX	72208133	Missense_Mutation	novel	L212F	0.08
LUSC	chrX	72206236	Missense_Mutation	NA	Q844R	0.4
OV	chrX	72206518	Missense_Mutation	rs777094514	P750L	0.07
OV	chrX	72206444	Missense_Mutation	novel	V775I	0.16
OV	chrX	72208432	Missense_Mutation	rs777548557	R112K	0.07	ResIII
OV	chrX	72207883	Missense_Mutation	NA	T295S	0.89
OV	chrX	72204838	3'UTR	novel		0.08
OV	chrX	72207504	Silent	novel	A421A	0.04
OV	chrX	72204838	3'UTR	novel		0.1
OV	chrX	72208698	Missense_Mutation	novel	R23S	0.04	ResIII
OV	chrX	72204838	3'UTR	novel		0.09
PAAD	chrX	72207685	Frame_Shift_Ins	novel	*L361Pfs6**	0.23
PCPG	chrX	72205331	Missense_Mutation	novel	P1146T	0.48
PRAD	chrX	72205525	Missense_Mutation	novel	S1081T	0.13
READ	chrX	72208441	Missense_Mutation	NA	S109N	0.53	ResIII
READ	chrX	72205706	Missense_Mutation	novel	S1021G	0.06
READ	chrX	72207770	Missense_Mutation	rs746565139	V333I	0.53
READ	chrX	72205513	Missense_Mutation	novel	K1085T	0.06
READ	chrX	72207031	Missense_Mutation	novel	V579A	0.05
READ	chrX	72207253	Missense_Mutation	NA	R505Q	0.18
READ	chrX	72207723	Missense_Mutation	NA	K348N	0.82
READ	chrX	72207230	Missense_Mutation	novel	L513V	0.36
READ	chrX	72205379	Missense_Mutation	NA	G1130R	0.74
READ	chrX	72207182	Missense_Mutation	NA	Y529H	0.85
SARC	chrX	72205070	Missense_Mutation	novel	D1233Y	0.29
SKCM	chrX	72205763	Missense_Mutation	novel	E1002K	0.56
SKCM	chrX	72207543	Silent	NA	K408K	0.45
SKCM	chrX	72206084	Missense_Mutation	novel	P895S	0.41
SKCM	chrX	72206160	Silent	NA	L869L	0.29
SKCM	chrX	72205324	Missense_Mutation	novel	G1148E	0.9
SKCM	chrX	72205325	Missense_Mutation	rs78660817	G1148R	0.88
SKCM	chrX	72208231	Missense_Mutation	rs759122393	P179L	0.68
SKCM	chrX	72208232	Missense_Mutation	novel	P179S	0.68
SKCM	chrX	72207349	Missense_Mutation	NA	R473Q	0.21
SKCM	chrX	72206020	Missense_Mutation	NA	E916G	0.74
SKCM	chrX	72207507	Silent	NA	R420R	0.13
SKCM	chrX	72207220	Missense_Mutation	NA	R516Q	0.17
SKCM	chrX	72208275	Silent	novel	F164F	0.1
SKCM	chrX	72207528	Silent	NA	H413H	0.96
SKCM	chrX	72207582	Missense_Mutation	NA	M395I	0.1
SKCM	chrX	72205340	Missense_Mutation	NA	E1143K	0.29
SKCM	chrX	72207678	Silent	rs761863545	R363R	0.33
SKCM	chrX	72205130	Missense_Mutation	NA	C1213R	0.21
STAD	chrX	72208112	Missense_Mutation	novel	E219K	0.58
STAD	chrX	72205440	Silent	NA	D1109D	0.32
STAD	chrX	72205869	Missense_Mutation	NA	N966K	0.54
STAD	chrX	72208158	Silent	novel	Q203Q	0.85
STAD	chrX	72205978	Missense_Mutation	NA	D930V	0.07
STAD	chrX	72208492	Missense_Mutation	NA	L92P	0.31	ResIII
STAD	chrX	72207576	Silent	rs776324309	T397T	0.21
STAD	chrX	72206198	Frame_Shift_Del	novel	*L857Afs9**	0.18
STAD	chrX	72205325	Missense_Mutation	rs78660817	G1148R	0.56
STAD	chrX	72208416	Silent	NA	G117G	0.28
STAD	chrX	72206954	Frame_Shift_Del	novel	*L604Kfs6**	0.63
STAD	chrX	72205508	Missense_Mutation	NA	M1087V	0.58
STAD	chrX	72205192	Missense_Mutation	novel	K1192T	0.21
UCEC	chrX	72206412	Missense_Mutation	NA	E785D	0.35
UCEC	chrX	72238918	5'UTR	rs757328589		0.29
UCEC	chrX	72205506	Missense_Mutation	NA	M1087I	0.17
UCEC	chrX	72207723	Missense_Mutation	NA	K348N	0.03
UCEC	chrX	72207771	Silent	rs780525195	D332D	0.03
UCEC	chrX	72205077	Silent	novel	K1230K	0.21
UCEC	chrX	72205835	Nonsense_Mutation	novel	E978*	0.19
UCEC	chrX	72206699	Missense_Mutation	novel	V690M	0.19
UCEC	chrX	72207622	Missense_Mutation	novel	R382M	0.54
UCEC	chrX	72238908	Missense_Mutation	novel	E2K	0.53	ResIII
UCEC	chrX	72206237	Nonsense_Mutation	novel	Q844*	0.46
UCEC	chrX	72204838	3'UTR	novel		0.12
UCEC	chrX	72207602	Missense_Mutation	NA	H389N	0.37
UCEC	chrX	72204838	3'UTR	novel		0.13
UCEC	chrX	72204994	3'UTR	novel		0.28
UCEC	chrX	72207294	Silent	novel	I491I	0.41
UCEC	chrX	72207951	Missense_Mutation	novel	D272E	0.19
UCEC	chrX	72206480	Missense_Mutation	novel	T763A	0.28
UCEC	chrX	72207510	Silent	novel	A419A	0.37
UCEC	chrX	72207220	Missense_Mutation	NA	R516Q	0.2
UCEC	chrX	72206690	Nonsense_Mutation	NA	E693*	0.17
UCEC	chrX	72206554	Missense_Mutation	NA	S738Y	0.15
UCEC	chrX	72205843	Frame_Shift_Ins	novel	*V975Dfs9**	0.12
UCEC	chrX	72208644	Silent	novel	F41F	0.41
UCEC	chrX	72205133	Nonsense_Mutation	NA	E1212*	0.2
UCEC	chrX	72207276	Missense_Mutation	NA	K497N	0.29
UCEC	chrX	72206636	Missense_Mutation	rs750289131	E711K	0.22
UCEC	chrX	72205459	Missense_Mutation	NA	V1103A	0.57
UCEC	chrX	72205988	Missense_Mutation	NA	A927T	0.51
UCEC	chrX	72207253	Missense_Mutation	NA	R505Q	0.42
UCEC	chrX	72204838	3'UTR	novel		0.42
UCEC	chrX	72204927	3'UTR	novel		0.26
UCEC	chrX	72205273	Missense_Mutation	novel	P1165L	0.08
UCEC	chrX	72206268	Missense_Mutation	novel	E833D	0.29
UCEC	chrX	72206881	Missense_Mutation	rs201713434	T629I	0.11
UCEC	chrX	72208280	Nonsense_Mutation	novel	E163*	0.36
UCEC	chrX	72206541	Missense_Mutation	novel	K742N	0.29
UCEC	chrX	72206682	Silent	novel	H695H	0.44
UCEC	chrX	72207253	Missense_Mutation	NA	R505Q	0.25
UCEC	chrX	72207602	Missense_Mutation	NA	H389N	0.17
UCEC	chrX	72208280	Nonsense_Mutation	novel	E163*	0.17
UCEC	chrX	72205072	Missense_Mutation	novel	A1232V	0.24
UCEC	chrX	72207287	Missense_Mutation	rs765128241	R494C	0.16
UCEC	chrX	72207995	Missense_Mutation	novel	T258A	0.27
UCEC	chrX	72206298	Silent	novel	E823E	0.47
UCEC	chrX	72207723	Missense_Mutation	NA	K348N	0.13
UCEC	chrX	72208198	Missense_Mutation	rs778615639	R190Q	0.45
UCEC	chrX	72205431	Silent	NA	E1112E	0.39
UCEC	chrX	72206570	Missense_Mutation	novel	E733K	0.45
UCEC	chrX	72208563	Silent	rs377168003	E68E	0.5
UCEC	chrX	72207543	Missense_Mutation	NA	K408N	0.3
UCEC	chrX	72206900	Nonsense_Mutation	novel	E623*	0.27
UCEC	chrX	72207211	Missense_Mutation	novel	R519I	0.29
UCEC	chrX	72207467	Missense_Mutation	novel	D434Y	0.16
UCEC	chrX	72208186	Missense_Mutation	novel	R194M	0.32
UCEC	chrX	72205572	Silent	novel	K1065K	0.33
UCEC	chrX	72205676	Missense_Mutation	rs752142569	E1031K	0.3
UCEC	chrX	72206883	Silent	rs112298003	F628F	0.24
UCEC	chrX	72208545	Nonsense_Mutation	novel	*D76Yfs5**	0.04	ResIII
UCEC	chrX	72205443	Missense_Mutation	novel	E1108D	0.09
UCEC	chrX	72238897	Silent	novel	R5R	0.16
UCEC	chrX	72207331	Missense_Mutation	novel	T479I	0.41
UCEC	chrX	72207845	Missense_Mutation	novel	A308S	0.38
UCEC	chrX	72208662	Silent	novel	G35G	0.33
UCEC	chrX	72206923	Missense_Mutation	novel	P615H	0.22
UCEC	chrX	72207518	Missense_Mutation	novel	L417M	0.42
UCEC	chrX	72208072	Missense_Mutation	novel	K232I	0.56
UCEC	chrX	72208479	Silent	novel	L96L	0.49
UCEC	chrX	72204838	3'UTR	novel		0.14
UCEC	chrX	72204838	3'UTR	novel		0.16
UCEC	chrX	72206103	Missense_Mutation	NA	E888D	0.46
UCEC	chrX	72208280	Nonsense_Mutation	novel	E163*	0.05
UCEC	chrX	72208551	Silent	novel	E72E	0.08
UCEC	chrX	72206146	Missense_Mutation	novel	K874R	0.13
UCEC	chrX	72208578	Missense_Mutation	novel	I63M	0.17	ResIII
UCEC	chrX	72207838	Missense_Mutation	novel	G310V	0.29
UCEC	chrX	72204838	3'UTR	novel		0.26
UCEC	chrX	72208545	Frame_Shift_Ins	novel	*D75Rfs2**	0.05	ResIII
UCEC	chrX	72208546	Nonsense_Mutation	novel	*G74Efs2**	0.05	ResIII
UCEC	chrX	72207313	Missense_Mutation	rs762834270	S485L	0.12
UCEC	chrX	72207575	Missense_Mutation	rs144123832	R398C	0.06
UCEC	chrX	72207637	Frame_Shift_Ins	novel	*Q377Pfs45**	0.02
UCEC	chrX	72208114	Frame_Shift_Ins	novel	*Q218Lfs17**	0.05
UCEC	chrX	72207652	Missense_Mutation	NA	R372Q	0.36
UCEC	chrX	72205676	Missense_Mutation	rs752142569	E1031K	0.43
UCEC	chrX	72206876	Missense_Mutation	rs147328766	E631K	0.45
UCEC	chrX	72207052	Missense_Mutation	NA	R572Q	0.34
UCEC	chrX	72205510	Missense_Mutation	NA	S1086Y	0.39
UCEC	chrX	72207672	Frame_Shift_Ins	novel	*N365Kfs2**	0.46
UCEC	chrX	72206690	Nonsense_Mutation	NA	E693*	0.26
UCEC	chrX	72205983	Silent	NA	L928L	0.35
UCEC	chrX	72206636	Missense_Mutation	rs750289131	E711K	0.39
UCEC	chrX	72206918	Nonsense_Mutation	novel	R617*	0.06
UCEC	chrX	72207747	Missense_Mutation	novel	N340K	0.05
UCEC	chrX	72205422	Silent	rs748979456	D1115D	0.35
UCEC	chrX	72206877	Silent	novel	I630I	0.36
UCEC	chrX	72205316	Silent	NA	L1151L	0.35
UCEC	chrX	72207576	Silent	rs776324309	T397T	0.45
UCEC	chrX	72206463	Silent	novel	I768I	0.37
UCEC	chrX	72207770	Missense_Mutation	rs746565139	V333I	0.41
UCS	chrX	72205254	Missense_Mutation	novel	E1171D	0.45
UCS	chrX	72205492	Missense_Mutation	novel	S1092Y	0.28
UVM	chrX	72207249	Silent	novel	I506I	0.24

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
THCA	DEL	0	0.21991

Survival Analysis

Cancer	P-value	Q-value
THYM	0.011	Kaplan-Meier Survival Analysis
KIRC	0.0001	Kaplan-Meier Survival Analysis
STAD	0.0037	Kaplan-Meier Survival Analysis
SARC	0.011	Kaplan-Meier Survival Analysis
ACC	0.00012	Kaplan-Meier Survival Analysis
SKCM	0.025	Kaplan-Meier Survival Analysis
PRAD	0.043	Kaplan-Meier Survival Analysis
BRCA	0.0025	Kaplan-Meier Survival Analysis
KIRP	0.00011	Kaplan-Meier Survival Analysis
PAAD	0.00016	Kaplan-Meier Survival Analysis
PCPG	0.039	Kaplan-Meier Survival Analysis
KICH	0.001	Kaplan-Meier Survival Analysis
UCEC	0.0054	Kaplan-Meier Survival Analysis
LIHC	0.0001	Kaplan-Meier Survival Analysis
CHOL	0.02	Kaplan-Meier Survival Analysis
LUAD	0.0014	Kaplan-Meier Survival Analysis
UVM	0.019	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000186871 (Gene tree)
Gene ID: 54821
Gene Symbol: ERCC6L
Alias: FLJ20105|PICH|RAD26L
Full Name: ERCC excision repair 6 like, spindle assembly checkpoint helicase
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 34,391 bases
Position: chrX:72,204,657-72,239,047
Accession: 20794
RBP type: canonical RBP
Summary: This gene encodes a member of the SWItch/Sucrose Non-Fermentable (SWI/SNF2) family of proteins, and contains a SNF2-like ATPase domain and a PICH family domain. One distinguishing feature of this SWI/SNF protein family member is that during interphase, the protein is excluded from the nucleus, and only associates with chromatin after the nuclear envelope has broken down. This protein is a DNA translocase that is thought to bind double-stranded DNA that is exposed to stretching forces, such as those exerted by the mitotic spindle. This protein associates with ribosomal DNA and ultra-fine DNA bridges (UFBs), fine structures that connect sister chromatids during anaphase at some sites such as fragile sites, telomeres and centromeres. This gene is required for the faithful segregation of sister chromatids during mitosis, and the ATPase activity of this protein required for the resolution of UFBs before cytokinesis. [provided by RefSeq, May 2017]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000334675	ResIII	PF04851.15	6.5e-13	1	1
ENSP00000362761	ResIII	PF04851.15	1.8e-10	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000334463	ERCC6L-201	4243	-	ENSP00000334675	1250 (aa)	-	Q2NKX8
ENST00000373657	ERCC6L-202	4344	-	ENSP00000362761	1127 (aa)	-	B5MDQ0

Gene Model

Click here to download ENSG00000186871's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000186871's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000186871	ERCC6L	53	62.727	ENSAPOG00000011392	ercc6l	98	62.727	Acanthochromis_polyacanthus
ENSG00000186871	ERCC6L	99	80.717	ENSAMEG00000005804	ERCC6L	100	80.717	Ailuropoda_melanoleuca
ENSG00000186871	ERCC6L	70	57.935	ENSAOCG00000016285	-	75	58.612	Amphiprion_ocellaris
ENSG00000186871	ERCC6L	77	60.908	ENSAPEG00000022533	ERCC6L	83	60.908	Amphiprion_percula
ENSG00000186871	ERCC6L	77	60.029	ENSAPEG00000022499	ercc6l	84	57.935	Amphiprion_percula
ENSG00000186871	ERCC6L	73	64.496	ENSATEG00000012969	ercc6l	83	62.567	Anabas_testudineus
ENSG00000186871	ERCC6L	52	67.622	ENSACAG00000028866	-	93	66.866	Anolis_carolinensis
ENSG00000186871	ERCC6L	92	53.515	ENSACAG00000001226	-	99	53.436	Anolis_carolinensis
ENSG00000186871	ERCC6L	53	67.450	ENSACAG00000029354	-	96	66.716	Anolis_carolinensis
ENSG00000186871	ERCC6L	99	93.541	ENSANAG00000022378	ERCC6L	99	93.541	Aotus_nancymaae
ENSG00000186871	ERCC6L	59	63.378	ENSACLG00000006555	ercc6l	59	63.378	Astatotilapia_calliptera
ENSG00000186871	ERCC6L	73	65.884	ENSAMXG00000004780	ercc6l	79	64.334	Astyanax_mexicanus
ENSG00000186871	ERCC6L	99	82.390	ENSBTAG00000005607	ERCC6L	99	82.550	Bos_taurus
ENSG00000186871	ERCC6L	99	91.946	ENSCJAG00000022332	ERCC6L	99	91.946	Callithrix_jacchus
ENSG00000186871	ERCC6L	99	80.812	ENSCAFG00000023690	ERCC6L	98	80.812	Canis_familiaris
ENSG00000186871	ERCC6L	99	79.523	ENSCAFG00020021313	ERCC6L	99	79.523	Canis_lupus_dingo
ENSG00000186871	ERCC6L	99	81.912	ENSCHIG00000009967	ERCC6L	99	81.912	Capra_hircus
ENSG00000186871	ERCC6L	99	86.523	ENSTSYG00000013701	ERCC6L	99	86.523	Carlito_syrichta
ENSG00000186871	ERCC6L	99	76.856	ENSCPOG00000011407	ERCC6L	99	76.856	Cavia_porcellus
ENSG00000186871	ERCC6L	99	93.142	ENSCCAG00000023790	ERCC6L	99	93.142	Cebus_capucinus
ENSG00000186871	ERCC6L	100	97.440	ENSCATG00000038031	ERCC6L	100	97.440	Cercocebus_atys
ENSG00000186871	ERCC6L	99	75.530	ENSCLAG00000017785	-	99	75.458	Chinchilla_lanigera
ENSG00000186871	ERCC6L	99	77.787	ENSCLAG00000015218	-	99	78.185	Chinchilla_lanigera
ENSG00000186871	ERCC6L	100	97.259	ENSCSAG00000011173	ERCC6L	99	96.166	Chlorocebus_sabaeus
ENSG00000186871	ERCC6L	99	51.695	ENSCPBG00000011965	ERCC6L	82	72.233	Chrysemys_picta_bellii
ENSG00000186871	ERCC6L	100	96.880	ENSCANG00000016909	ERCC6L	100	96.880	Colobus_angolensis_palliatus
ENSG00000186871	ERCC6L	100	74.153	ENSCGRG00001016668	Ercc6l	100	74.310	Cricetulus_griseus_chok1gshd
ENSG00000186871	ERCC6L	100	74.153	ENSCGRG00000006223	Ercc6l	100	74.310	Cricetulus_griseus_crigri
ENSG00000186871	ERCC6L	72	64.869	ENSCSEG00000010268	ercc6l	68	61.696	Cynoglossus_semilaevis
ENSG00000186871	ERCC6L	55	61.877	ENSCVAG00000008090	ercc6l	96	61.877	Cyprinodon_variegatus
ENSG00000186871	ERCC6L	67	62.435	ENSDARG00000002479	ercc6l	63	62.581	Danio_rerio
ENSG00000186871	ERCC6L	99	81.659	ENSDNOG00000032356	ERCC6L	99	81.659	Dasypus_novemcinctus
ENSG00000186871	ERCC6L	99	75.639	ENSDORG00000007865	Ercc6l	99	75.520	Dipodomys_ordii
ENSG00000186871	ERCC6L	90	90.311	ENSETEG00000018007	ERCC6L	94	90.311	Echinops_telfairi
ENSG00000186871	ERCC6L	99	82.686	ENSEASG00005007025	ERCC6L	99	82.686	Equus_asinus_asinus
ENSG00000186871	ERCC6L	99	83.825	ENSECAG00000002513	ERCC6L	99	83.825	Equus_caballus
ENSG00000186871	ERCC6L	94	88.584	ENSEEUG00000015724	ERCC6L	94	88.584	Erinaceus_europaeus
ENSG00000186871	ERCC6L	83	66.303	ENSELUG00000007917	ercc6l	99	47.494	Esox_lucius
ENSG00000186871	ERCC6L	99	81.876	ENSFCAG00000012038	ERCC6L	99	81.876	Felis_catus
ENSG00000186871	ERCC6L	99	50.683	ENSFALG00000011797	ERCC6L	99	50.951	Ficedula_albicollis
ENSG00000186871	ERCC6L	99	78.088	ENSFDAG00000019713	ERCC6L	99	78.088	Fukomys_damarensis
ENSG00000186871	ERCC6L	52	61.920	ENSFHEG00000007269	-	94	61.920	Fundulus_heteroclitus
ENSG00000186871	ERCC6L	57	63.762	ENSFHEG00000007205	ercc6l	79	61.558	Fundulus_heteroclitus
ENSG00000186871	ERCC6L	99	51.469	ENSGALG00000003881	ERCC6L	99	52.267	Gallus_gallus
ENSG00000186871	ERCC6L	99	52.519	ENSGAGG00000018784	ERCC6L	99	52.775	Gopherus_agassizii
ENSG00000186871	ERCC6L	100	99.379	ENSGGOG00000022367	ERCC6L	100	99.360	Gorilla_gorilla
ENSG00000186871	ERCC6L	56	65.881	ENSHBUG00000007810	ercc6l	60	63.870	Haplochromis_burtoni
ENSG00000186871	ERCC6L	99	79.124	ENSHGLG00000016594	ERCC6L	99	79.124	Heterocephalus_glaber_female
ENSG00000186871	ERCC6L	99	79.124	ENSHGLG00100003339	ERCC6L	99	79.124	Heterocephalus_glaber_male
ENSG00000186871	ERCC6L	70	66.389	ENSHCOG00000001051	ercc6l	64	63.830	Hippocampus_comes
ENSG00000186871	ERCC6L	57	63.472	ENSIPUG00000016117	ercc6l	57	63.472	Ictalurus_punctatus
ENSG00000186871	ERCC6L	99	75.177	ENSJJAG00000022875	Ercc6l	98	76.075	Jaculus_jaculus
ENSG00000186871	ERCC6L	65	61.282	ENSKMAG00000011587	ercc6l	67	61.200	Kryptolebias_marmoratus
ENSG00000186871	ERCC6L	73	62.725	ENSLBEG00000000091	ercc6l	80	61.176	Labrus_bergylta
ENSG00000186871	ERCC6L	98	48.206	ENSLACG00000002634	ERCC6L	99	48.006	Latimeria_chalumnae
ENSG00000186871	ERCC6L	99	47.595	ENSLOCG00000013925	ercc6l	99	48.468	Lepisosteus_oculatus
ENSG00000186871	ERCC6L	99	79.761	ENSLAFG00000014985	ERCC6L	100	79.761	Loxodonta_africana
ENSG00000186871	ERCC6L	100	97.680	ENSMFAG00000045509	ERCC6L	100	97.680	Macaca_fascicularis
ENSG00000186871	ERCC6L	100	97.680	ENSMMUG00000012957	ERCC6L	100	97.680	Macaca_mulatta
ENSG00000186871	ERCC6L	100	97.680	ENSMNEG00000030867	ERCC6L	100	97.680	Macaca_nemestrina
ENSG00000186871	ERCC6L	100	97.200	ENSMLEG00000000190	ERCC6L	100	97.200	Mandrillus_leucophaeus
ENSG00000186871	ERCC6L	59	63.378	ENSMZEG00005001556	ercc6l	59	63.378	Maylandia_zebra
ENSG00000186871	ERCC6L	99	51.893	ENSMGAG00000002094	ERCC6L	99	52.811	Meleagris_gallopavo
ENSG00000186871	ERCC6L	99	74.185	ENSMAUG00000015560	Ercc6l	98	75.264	Mesocricetus_auratus
ENSG00000186871	ERCC6L	99	86.572	ENSMICG00000035415	ERCC6L	99	86.534	Microcebus_murinus
ENSG00000186871	ERCC6L	99	73.806	ENSMOCG00000021344	Ercc6l	99	73.806	Microtus_ochrogaster
ENSG00000186871	ERCC6L	72	66.181	ENSMMOG00000020762	ercc6l	93	75.177	Mola_mola
ENSG00000186871	ERCC6L	98	58.435	ENSMODG00000010916	ERCC6L	98	58.598	Monodelphis_domestica
ENSG00000186871	ERCC6L	99	45.129	ENSMALG00000003609	ercc6l	99	44.812	Monopterus_albus
ENSG00000186871	ERCC6L	71	54.116	ENSMALG00000003561	-	56	61.260	Monopterus_albus
ENSG00000186871	ERCC6L	99	72.178	MGP_CAROLIEiJ_G0033297	Ercc6l	99	72.258	Mus_caroli
ENSG00000186871	ERCC6L	99	72.597	ENSMUSG00000051220	Ercc6l	99	72.836	Mus_musculus
ENSG00000186871	ERCC6L	99	72.879	MGP_PahariEiJ_G0031835	Ercc6l	99	73.117	Mus_pahari
ENSG00000186871	ERCC6L	99	72.633	MGP_SPRETEiJ_G0034461	Ercc6l	99	72.893	Mus_spretus
ENSG00000186871	ERCC6L	99	78.725	ENSMPUG00000005291	ERCC6L	99	78.725	Mustela_putorius_furo
ENSG00000186871	ERCC6L	98	83.725	ENSMLUG00000011670	ERCC6L	99	83.725	Myotis_lucifugus
ENSG00000186871	ERCC6L	100	77.884	ENSNGAG00000021063	Ercc6l	100	77.407	Nannospalax_galili
ENSG00000186871	ERCC6L	100	98.160	ENSNLEG00000036284	ERCC6L	100	98.160	Nomascus_leucogenys
ENSG00000186871	ERCC6L	99	74.028	ENSODEG00000002328	ERCC6L	99	74.898	Octodon_degus
ENSG00000186871	ERCC6L	79	64.253	ENSONIG00000000589	ercc6l	88	62.614	Oreochromis_niloticus
ENSG00000186871	ERCC6L	100	56.969	ENSOANG00000014708	ERCC6L	98	58.960	Ornithorhynchus_anatinus
ENSG00000186871	ERCC6L	98	82.996	ENSOCUG00000008724	ERCC6L	99	82.996	Oryctolagus_cuniculus
ENSG00000186871	ERCC6L	54	57.353	ENSORLG00000024240	ercc6l	95	57.500	Oryzias_latipes
ENSG00000186871	ERCC6L	76	65.635	ENSORLG00020014999	ercc6l	73	59.440	Oryzias_latipes_hni
ENSG00000186871	ERCC6L	67	59.796	ENSOMEG00000009481	ercc6l	66	59.796	Oryzias_melastigma
ENSG00000186871	ERCC6L	99	84.894	ENSOGAG00000034301	-	100	85.888	Otolemur_garnettii
ENSG00000186871	ERCC6L	100	84.897	ENSOGAG00000031470	-	100	85.135	Otolemur_garnettii
ENSG00000186871	ERCC6L	99	81.890	ENSOARG00000005908	ERCC6L	99	82.524	Ovis_aries
ENSG00000186871	ERCC6L	100	99.600	ENSPPAG00000031861	ERCC6L	100	99.600	Pan_paniscus
ENSG00000186871	ERCC6L	98	81.700	ENSPPRG00000012408	ERCC6L	99	81.700	Panthera_pardus
ENSG00000186871	ERCC6L	100	99.680	ENSPTRG00000022023	ERCC6L	100	99.680	Pan_troglodytes
ENSG00000186871	ERCC6L	100	97.680	ENSPANG00000011598	ERCC6L	100	97.680	Papio_anubis
ENSG00000186871	ERCC6L	79	63.241	ENSPKIG00000022325	ercc6l	75	64.817	Paramormyrops_kingsleyae
ENSG00000186871	ERCC6L	99	52.977	ENSPSIG00000004789	ERCC6L	99	53.244	Pelodiscus_sinensis
ENSG00000186871	ERCC6L	55	64.460	ENSPMGG00000023343	ercc6l	74	65.036	Periophthalmus_magnuspinnatus
ENSG00000186871	ERCC6L	99	74.306	ENSPEMG00000007920	Ercc6l	99	74.306	Peromyscus_maniculatus_bairdii
ENSG00000186871	ERCC6L	63	55.680	ENSPMAG00000005064	ercc6l	98	58.881	Petromyzon_marinus
ENSG00000186871	ERCC6L	99	61.031	ENSPCIG00000026973	ERCC6L	96	61.365	Phascolarctos_cinereus
ENSG00000186871	ERCC6L	64	65.142	ENSPFOG00000010410	ercc6l	74	62.302	Poecilia_formosa
ENSG00000186871	ERCC6L	66	64.673	ENSPLAG00000005575	ercc6l	76	64.673	Poecilia_latipinna
ENSG00000186871	ERCC6L	67	63.172	ENSPMEG00000016911	ercc6l	74	62.616	Poecilia_mexicana
ENSG00000186871	ERCC6L	60	65.932	ENSPREG00000017617	ercc6l	69	65.932	Poecilia_reticulata
ENSG00000186871	ERCC6L	100	98.640	ENSPPYG00000020461	ERCC6L	100	98.640	Pongo_abelii
ENSG00000186871	ERCC6L	62	88.624	ENSPCAG00000002981	-	69	88.624	Procavia_capensis
ENSG00000186871	ERCC6L	99	87.171	ENSPCOG00000024286	ERCC6L	99	87.171	Propithecus_coquereli
ENSG00000186871	ERCC6L	100	71.848	ENSPVAG00000013596	ERCC6L	100	71.848	Pteropus_vampyrus
ENSG00000186871	ERCC6L	82	65.566	ENSPNYG00000013185	ercc6l	86	63.636	Pundamilia_nyererei
ENSG00000186871	ERCC6L	57	67.179	ENSPNAG00000006556	ercc6l	97	49.744	Pygocentrus_nattereri
ENSG00000186871	ERCC6L	99	72.611	ENSRNOG00000003208	Ercc6l	99	72.771	Rattus_norvegicus
ENSG00000186871	ERCC6L	100	96.185	ENSRBIG00000036588	ERCC6L	100	96.293	Rhinopithecus_bieti
ENSG00000186871	ERCC6L	100	97.360	ENSRROG00000042561	ERCC6L	100	97.360	Rhinopithecus_roxellana
ENSG00000186871	ERCC6L	99	92.504	ENSSBOG00000029416	ERCC6L	99	92.504	Saimiri_boliviensis_boliviensis
ENSG00000186871	ERCC6L	99	60.946	ENSSHAG00000012578	-	99	60.803	Sarcophilus_harrisii
ENSG00000186871	ERCC6L	90	61.165	ENSSHAG00000001331	-	100	60.724	Sarcophilus_harrisii
ENSG00000186871	ERCC6L	76	67.353	ENSSFOG00015009709	ercc6l	72	64.418	Scleropages_formosus
ENSG00000186871	ERCC6L	51	41.837	ENSSFOG00015014557	-	50	42.656	Scleropages_formosus
ENSG00000186871	ERCC6L	99	44.686	ENSSDUG00000013307	ercc6l	99	44.631	Seriola_dumerili
ENSG00000186871	ERCC6L	57	62.345	ENSSLDG00000014910	ercc6l	65	62.345	Seriola_lalandi_dorsalis
ENSG00000186871	ERCC6L	85	67.890	ENSSPUG00000005866	ERCC6L	92	67.150	Sphenodon_punctatus
ENSG00000186871	ERCC6L	60	61.347	ENSSPAG00000018472	ercc6l	99	45.862	Stegastes_partitus
ENSG00000186871	ERCC6L	99	82.390	ENSSSCG00000021834	ERCC6L	99	82.390	Sus_scrofa
ENSG00000186871	ERCC6L	86	62.171	ENSTRUG00000012053	ercc6l	99	45.801	Takifugu_rubripes
ENSG00000186871	ERCC6L	99	83.360	ENSTTRG00000010777	ERCC6L	99	83.360	Tursiops_truncatus
ENSG00000186871	ERCC6L	99	78.975	ENSUAMG00000015605	ERCC6L	99	78.975	Ursus_americanus
ENSG00000186871	ERCC6L	99	79.240	ENSUMAG00000004863	ERCC6L	99	79.240	Ursus_maritimus
ENSG00000186871	ERCC6L	99	83.108	ENSVPAG00000010950	ERCC6L	99	83.108	Vicugna_pacos
ENSG00000186871	ERCC6L	99	80.748	ENSVVUG00000025512	ERCC6L	98	80.748	Vulpes_vulpes
ENSG00000186871	ERCC6L	98	50.355	ENSXETG00000022574	ercc6l	99	50.750	Xenopus_tropicalis
ENSG00000186871	ERCC6L	52	64.746	ENSXCOG00000011494	ercc6l	90	64.547	Xiphophorus_couchianus
ENSG00000186871	ERCC6L	82	67.446	ENSXMAG00000000948	ercc6l	74	65.236	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000777	condensed chromosome kinetochore	-	IEA	Component
GO:0003677	DNA binding	-	IEA	Function
GO:0004386	helicase activity	-	IEA	Function
GO:0005515	protein binding	20360068.23275563.25416956.26496610.28977671.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005829	cytosol	-	TAS	Component
GO:0007049	cell cycle	-	IEA	Process
GO:0015616	DNA translocase activity	23973328.	IDA	Function
GO:0016020	membrane	19946888.	HDA	Component
GO:0051301	cell division	-	IEA	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.