EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
BLCA	chr15	40335358	Missense_Mutation	novel	E469K	0.35
BLCA	chr15	40339996	Missense_Mutation	NA	S55F	0.69
BLCA	chr15	40335321	Missense_Mutation	NA	G481E	0.16
BLCA	chr15	40335288	Missense_Mutation	novel	S492F	0.53
BLCA	chr15	40335132	3'UTR	novel		0.21
BLCA	chr15	40337838	Frame_Shift_Ins	novel	*D234Gfs26**	0.26
BLCA	chr15	40335358	Missense_Mutation	novel	E469K	0.59
BLCA	chr15	40340862	Silent	novel	L30L	0.27
BLCA	chr15	40338909	Splice_Region	novel		0.11
BLCA	chr15	40335307	Missense_Mutation	novel	E486K	0.18
BLCA	chr15	40335308	Silent	rs372988249	P485P	0.19
BLCA	chr15	40339453	Intron	novel		0.39
BLCA	chr15	40335354	Missense_Mutation	NA	L470P	0.33
BLCA	chr15	40340021	Splice_Region	novel		0.36
BLCA	chr15	40338750	Missense_Mutation	novel	E173K	0.43
BRCA	chr15	40339957	Missense_Mutation	NA	R68Q	0.16
BRCA	chr15	40331711	3'Flank	novel		0.62
BRCA	chr15	40335139	3'UTR	novel		0.28
BRCA	chr15	40335455	Frame_Shift_Ins	novel	*C437Vfs21**	0.32
BRCA	chr15	40339935	Missense_Mutation	NA	K75N	0.32
BRCA	chr15	40338977	Intron	novel		0.18
BRCA	chr15	40335523	Missense_Mutation	NA	E414Q	0.18
BRCA	chr15	40337751	Missense_Mutation	novel	P263R	0.5
CESC	chr15	40335786	Missense_Mutation	novel	E354K	0.32
CESC	chr15	40331679	3'Flank	novel		0.43
CESC	chr15	40339979	Missense_Mutation	NA	E61Q	0.27
CESC	chr15	40337759	Nonsense_Mutation	novel	W260*	0.29
CESC	chr15	40335105	3'UTR	novel		0.39
CESC	chr15	40340876	Frame_Shift_Del	novel	*L26Sfs32**	0.14
CESC	chr15	40335656	Silent	novel	A369A	0.27
CESC	chr15	40337341	Intron	novel		0.26
CESC	chr15	40331711	3'Flank	novel		0.2
CHOL	chr15	40336577	Missense_Mutation	rs370895955	R339Q	0.41
CHOL	chr15	40340963	5'UTR	novel		0.32
COAD	chr15	40339581	Frame_Shift_Del	NA	*M99Wfs3**	0.35
COAD	chr15	40335006	3'UTR	novel		0.63
COAD	chr15	40338947	Intron	NA		0.23
COAD	chr15	40339614	Silent	NA	I87I	0.17
COAD	chr15	40340046	Intron	novel		0.25
COAD	chr15	40335326	Silent	NA	Q479Q	0.48
COAD	chr15	40339014	Intron	novel		0.6
COAD	chr15	40339581	Frame_Shift_Del	NA	*M99Wfs3**	0.38
COAD	chr15	40339581	Frame_Shift_Del	NA	*M99Wfs3**	0.32
COAD	chr15	40339581	Frame_Shift_Del	NA	*M99Wfs3**	0.43
COAD	chr15	40338782	Missense_Mutation	NA	V162A	0.25
COAD	chr15	40340903	Missense_Mutation	NA	G17C	0.37
COAD	chr15	40339971	Silent	NA	D63D	0.24
COAD	chr15	40337803	Missense_Mutation	NA	D246N	0.37
COAD	chr15	40339581	Frame_Shift_Del	NA	*M99Wfs3**	0.53
COAD	chr15	40335240	Missense_Mutation	rs572485964	T508M	0.7
COAD	chr15	40335467	Silent	novel	P432P	0.11
COAD	chr15	40339581	Frame_Shift_Del	NA	*M99Wfs3**	0.39
COAD	chr15	40335360	Missense_Mutation	NA	A468V	0.39
COAD	chr15	40338570	Frame_Shift_Ins	rs772754432	*T204Hfs56**	0.23
COAD	chr15	40336788	Silent	NA	Q300Q	0.41
COAD	chr15	40339581	Frame_Shift_Del	NA	*M99Wfs3**	0.16
ESCA	chr15	40336869	Intron	novel		0.52
ESCA	chr15	40331642	3'Flank	novel		0.33
GBM	chr15	40338620	Missense_Mutation	novel	N187S	0.51
GBM	chr15	40336689	Intron	novel		0.11
HNSC	chr15	40338832	Silent	rs778068788	E145E	0.1
HNSC	chr15	40337314	Intron	novel		0.16
HNSC	chr15	40338997	Intron	novel		0.23
HNSC	chr15	40336915	Intron	novel		0.2
HNSC	chr15	40338607	Missense_Mutation	rs548213771	E191D	0.24
HNSC	chr15	40338781	Silent	rs772371096	V162V	0.17
HNSC	chr15	40335326	Silent	NA	Q479Q	0.38
HNSC	chr15	40335327	Missense_Mutation	novel	Q479R	0.38
KIRC	chr15	40336600	Silent	NA	K331K	0.42
KIRP	chr15	40340878	Frame_Shift_Del	novel	*F25Sfs33**	0.26
KIRP	chr15	40339567	Missense_Mutation	rs762002395	T103I	0.45
LAML	chr15	40339396	Intron	novel		0.21
LIHC	chr15	40336794	Silent	rs143912259	K298K	0.54
LUAD	chr15	40338750	Missense_Mutation	NA	E173Q	0.23
LUAD	chr15	40339592	Missense_Mutation	novel	E95K	0.21
LUAD	chr15	40338567	Missense_Mutation	novel	Q205K	0.15
LUAD	chr15	40337815	Silent	novel	R242R	0.75
LUAD	chr15	40338826	Silent	novel	E147E	0.22
LUAD	chr15	40338605	Missense_Mutation	novel	G192V	0.38
LUAD	chr15	40336595	Missense_Mutation	NA	R333K	0.17
LUAD	chr15	40338568	Silent	rs751019527	T204T	0.05
LUAD	chr15	40336577	Missense_Mutation	rs370895955	R339Q	0.1
LUSC	chr15	40338822	Missense_Mutation	novel	A149T	0.22
LUSC	chr15	40335218	Silent	NA	S515S	0.17
LUSC	chr15	40335276	Missense_Mutation	novel	G496V	0.08
LUSC	chr15	40335240	Missense_Mutation	rs572485964	T508K	0.34
LUSC	chr15	40336769	Missense_Mutation	NA	D307H	0.26
LUSC	chr15	40336654	Frame_Shift_Del	novel	*Q314Kfs21**	0.31
LUSC	chr15	40336587	Missense_Mutation	NA	G336C	0.27
LUSC	chr15	40335195	Missense_Mutation	rs139346626	R523H	0.05
LUSC	chr15	40340868	Silent	NA	L28L	0.31
LUSC	chr15	40335255	Missense_Mutation	rs558204056	P503L	0.16
OV	chr15	40339966	Missense_Mutation	novel	E65V	0.28
OV	chr15	40337827	Frame_Shift_Del	novel	*W238Gfs10**	0.11
PAAD	chr15	40338993	Intron	novel		0.13
PRAD	chr15	40340953	5'UTR	novel		0.39
SARC	chr15	40336891	Intron	novel		0.41
SARC	chr15	40338581	Missense_Mutation	rs755954950	R200Q	0.3
SARC	chr15	40331781	3'Flank	novel		0.28
SKCM	chr15	40337357	Intron	novel		0.38
SKCM	chr15	40336821	Splice_Region	novel		0.41
SKCM	chr15	40335588	Missense_Mutation	novel	S392F	0.5
SKCM	chr15	40336661	Missense_Mutation	novel	R311Q	0.14
SKCM	chr15	40335085	3'UTR	novel		0.26
SKCM	chr15	40337425	Silent	NA	L279L	0.15
SKCM	chr15	40336856	Intron	novel		0.21
SKCM	chr15	40339944	Silent	NA	A72A	0.2
SKCM	chr15	40336828	Intron	novel		0.19
SKCM	chr15	40335419	Silent	novel	S448S	0.55
SKCM	chr15	40335094	3'UTR	novel		0.41
SKCM	chr15	40335216	Missense_Mutation	novel	R516K	0.38
STAD	chr15	40338878	Missense_Mutation	novel	W130S	0.84
STAD	chr15	40337869	Missense_Mutation	NA	P224S	0.29
STAD	chr15	40336879	Intron	novel		0.42
STAD	chr15	40336650	Frame_Shift_Ins	novel	*A315Sfs51**	0.3
STAD	chr15	40336716	Intron	novel		0.12
STAD	chr15	40337408	Missense_Mutation	NA	A285V	0.37
STAD	chr15	40336923	Intron	novel		0.24
STAD	chr15	40339581	Frame_Shift_Del	NA	*M99Wfs3**	0.31
STAD	chr15	40339581	Frame_Shift_Del	NA	*M99Wfs3**	0.14
STAD	chr15	40339581	Frame_Shift_Del	NA	*M99Wfs3**	0.16
STAD	chr15	40339581	Frame_Shift_Del	NA	*M99Wfs3**	0.14
THYM	chr15	40340963	5'UTR	novel		0.17
UCEC	chr15	40335028	3'UTR	novel		0.31
UCEC	chr15	40337225	Intron	novel		0.32
UCEC	chr15	40337438	Missense_Mutation	novel	D275G	0.26
UCEC	chr15	40340963	5'UTR	novel		0.47
UCEC	chr15	40339958	Missense_Mutation	NA	R68W	0.35
UCEC	chr15	40335374	Nonsense_Mutation	NA	W463*	0.32
UCEC	chr15	40340930	Nonsense_Mutation	novel	R8*	0.19
UCEC	chr15	40338958	Intron	novel		0.41
UCEC	chr15	40339460	Intron	novel		0.42
UCEC	chr15	40336694	Intron	NA		0.21
UCEC	chr15	40339581	Frame_Shift_Del	NA	*M99Wfs3**	0.41
UCEC	chr15	40338590	Frame_Shift_Del	NA	*R197Lfs2**	0.1
UCEC	chr15	40339580	Missense_Mutation	novel	M99V	0.4
UCEC	chr15	40335313	Missense_Mutation	novel	L484F	0.18
UCEC	chr15	40340023	Splice_Region	novel		0.28
UCEC	chr15	40340174	Intron	novel		0.3
UCEC	chr15	40339957	Missense_Mutation	NA	R68Q	0.16
UCEC	chr15	40336913	Intron	novel		0.56
UCEC	chr15	40337317	Intron	novel		0.55
UCEC	chr15	40334316	3'UTR	novel		0.36
UCEC	chr15	40335012	3'UTR	novel		0.56
UCEC	chr15	40338653	Missense_Mutation	NA	R176Q	0.42
UCEC	chr15	40338923	Intron	novel		0.39
UCEC	chr15	40336671	Splice_Region	novel		0.49
UCEC	chr15	40339581	Frame_Shift_Del	NA	*M99Wfs3**	1
UCEC	chr15	40338571	Frame_Shift_Del	NA	*T204Rfs44**	0.38
UCEC	chr15	40337408	Missense_Mutation	NA	A285V	0.42
UCEC	chr15	40339063	Intron	novel		0.21
UCEC	chr15	40335184	Missense_Mutation	rs369701147	R527C	0.39
UCEC	chr15	40338897	Missense_Mutation	rs761209673	R124W	0.47
UCEC	chr15	40339116	Intron	NA		0.54
UCEC	chr15	40339605	Missense_Mutation	novel	D90E	0.38
UCEC	chr15	40333995	3'UTR	novel		0.33
UCEC	chr15	40340899	Missense_Mutation	novel	P18Q	0.46
UCEC	chr15	40331646	3'Flank	novel		0.47
UCEC	chr15	40335235	Nonsense_Mutation	NA	G510*	0.28
UCEC	chr15	40336833	Intron	novel		0.17
UCEC	chr15	40339915	Missense_Mutation	novel	R82P	0.49
UCEC	chr15	40334219	3'UTR	rs781180605		0.39
UCEC	chr15	40336881	Intron	novel		0.3
UCEC	chr15	40338570	Frame_Shift_Ins	rs772754432	*T204Hfs56**	0.53
UCEC	chr15	40335255	Missense_Mutation	rs558204056	P503L	0.25
UCEC	chr15	40339542	Silent	novel	G111G	0.31
UCEC	chr15	40335247	Missense_Mutation	rs146699813	R506W	0.2
UCEC	chr15	40336781	Missense_Mutation	novel	P303S	0.21
UCEC	chr15	40338844	Silent	rs368967516	N141N	0.28
UCEC	chr15	40339458	Intron	novel		0.42
UCEC	chr15	40339566	Silent	novel	T103T	0.18
UCEC	chr15	40339939	Missense_Mutation	rs200856504	R74H	0.17
UCEC	chr15	40335095	3'UTR	novel		0.35
UCEC	chr15	40339974	Missense_Mutation	NA	K62N	0.35
UCEC	chr15	40339581	Frame_Shift_Del	NA	*M99Wfs3**	0.43
UCEC	chr15	40335570	Missense_Mutation	novel	G398V	0.43
UCEC	chr15	40336755	Splice_Region	novel		0.41
UCEC	chr15	40338940	Intron	novel		0.3

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	DEL	0.2222	0.079424
CESC	DEL	0.1966	0.00049652
COAD	DEL	0.3548	2.3878e-07
GBM	DEL	0.2184	3.453e-12
HNSC	DEL	0.1667	0.11567
KICH	AMP	0.2727	0.21756
KIRP	DEL	0.1111	0.2062
LUAD	DEL	0.3992	6.8561e-07
LUSC	DEL	0.2695	5.9764e-05
MESO	DEL	0.3103	4.5411e-10
PAAD	DEL	0.1359	0.13216
READ	DEL	0.4364	0.025797
SARC	DEL	0.1984	0.18974
UCEC	DEL	0.2375	7.1012e-08
UCS	DEL	0.6786	4.9548e-10

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.00033	Kaplan-Meier Survival Analysis
SARC	0.0031	Kaplan-Meier Survival Analysis
ACC	0.00024	Kaplan-Meier Survival Analysis
SKCM	0.027	Kaplan-Meier Survival Analysis
LUSC	0.048	Kaplan-Meier Survival Analysis
BRCA	0.0074	Kaplan-Meier Survival Analysis
ESCA	0.011	Kaplan-Meier Survival Analysis
KIRP	0.0082	Kaplan-Meier Survival Analysis
COAD	0.0064	Kaplan-Meier Survival Analysis
PAAD	0.013	Kaplan-Meier Survival Analysis
LAML	0.037	Kaplan-Meier Survival Analysis
UCEC	0.046	Kaplan-Meier Survival Analysis
GBM	0.015	Kaplan-Meier Survival Analysis
LGG	0.043	Kaplan-Meier Survival Analysis
THCA	0.046	Kaplan-Meier Survival Analysis
OV	0.0035	Kaplan-Meier Survival Analysis

Description

RBPome

Expression

Transcripts

Gene Model

PPI

Gene Ontology

Description

Ensembl ID: ENSG00000188549 (Gene tree)
Gene ID: 388115
Gene Symbol: CCDC9B
Alias: FLJ43339|C15orf52
Full Name: coiled-coil domain containing 9B
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 9,516 bases
Position: chr15:40,331,452-40,340,967
Accession: 33488
RBP type: non-canonical RBP
Summary: (Coiled-Coil Domain Containing 9B) is a Protein Coding gene. An important paralog of this gene is CCDC9.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000558912	CCDC9B-205	2790	-	-	- (aa)	-	-
ENST00000558858	CCDC9B-204	541	-	ENSP00000452677	34 (aa)	-	H0YK65
ENST00000557973	CCDC9B-203	326	-	-	- (aa)	-	-
ENST00000560922	CCDC9B-207	572	-	ENSP00000453500	173 (aa)	-	H0YM82
ENST00000559313	CCDC9B-206	3022	-	ENSP00000453969	534 (aa)	-	Q6ZUT6
ENST00000397536	CCDC9B-202	4717	-	ENSP00000380670	324 (aa)	-	Q6ZUT6
ENST00000382688	CCDC9B-201	5021	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000188549's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000188549's network

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22658674.	HDA	Function

Note: Click here to get the extension of tumor abbreviations.

Note: to get the extension of tumor abbreviations.