EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
BLCA	chr6	116279380	Missense_Mutation	NA	E151K	0.31
BLCA	chr6	116279038	Missense_Mutation	NA	L265V	0.08
BLCA	chr6	116279326	Missense_Mutation	NA	E169K	0.4
BLCA	chr6	116279875	5'UTR	novel		0.48
BLCA	chr6	116279386	Missense_Mutation	novel	E149K	0.7
BLCA	chr6	116279212	Missense_Mutation	rs758399636	E207K	0.89
BLCA	chr6	116279363	Missense_Mutation	novel	K156N	0.75
BLCA	chr6	116279479	Missense_Mutation	novel	D118N	0.59
BLCA	chr6	116279046	Missense_Mutation	NA	R262P	0.2
BLCA	chr6	116279386	Missense_Mutation	novel	E149Q	0.12
BRCA	chr6	116277465	3'UTR	novel		0.5
BRCA	chr6	116279518	Missense_Mutation	NA	A105T	0.12
BRCA	chr6	116278782	Missense_Mutation	novel	S350C	0.3
BRCA	chr6	116278611	Missense_Mutation	NA	Y407C	0.45
BRCA	chr6	116278922	Silent	novel	Y303Y	0.03
CESC	chr6	116279528	Silent	novel	G101G	0.3
CESC	chr6	116277364	3'UTR	novel		0.29
CESC	chr6	116279429	Silent	novel	I134I	0.45
CESC	chr6	116279617	Missense_Mutation	novel	Q72K	0.42
CESC	chr6	116279007	Missense_Mutation	NA	I275N	0.93
CESC	chr6	116279515	Missense_Mutation	rs377352006	E106K	0.48
CESC	chr6	116277146	3'UTR	novel		0.56
CESC	chr6	116278980	Missense_Mutation	novel	R284Q	0.63
COAD	chr6	116278573	Missense_Mutation	rs755262799	R420C	0.32
COAD	chr6	116279779	Missense_Mutation	NA	I18F	0.56
COAD	chr6	116279109	Missense_Mutation	NA	T241I	0.23
COAD	chr6	116278981	Nonsense_Mutation	NA	R284*	0.06
COAD	chr6	116278599	Missense_Mutation	rs537676463	R411H	0.42
ESCA	chr6	116279352	Missense_Mutation	novel	C160F	0.26
ESCA	chr6	116279463	Missense_Mutation	NA	K123R	0.48
GBM	chr6	116279536	Missense_Mutation	novel	E99K	0.3
GBM	chr6	116279102	Missense_Mutation	novel	N243K	0.14
GBM	chr6	116279698	Missense_Mutation	novel	V45M	0.39
HNSC	chr6	116278771	Missense_Mutation	novel	P354A	0.29
KIRC	chr6	116278640	Frame_Shift_Del	novel	*K397Rfs15**	0.28
KIRC	chr6	116279540	Frame_Shift_Del	novel	*Q98Rfs17**	0.2
LAML	chr6	116278670	Silent	novel	P387P	0.06
LGG	chr6	116279475	Missense_Mutation	novel	R119H	0.29
LIHC	chr6	116279386	Missense_Mutation	novel	E149Q	0.33
LUAD	chr6	116279326	Missense_Mutation	NA	E169K	0.16
LUAD	chr6	116279859	5'UTR	novel		0.17
LUAD	chr6	116279098	Missense_Mutation	novel	Q245E	0.2
LUSC	chr6	116279716	Missense_Mutation	NA	Q39K	0.14
LUSC	chr6	116279592	Missense_Mutation	novel	T80I	0.08
OV	chr6	116278963	Nonsense_Mutation	novel	*S290Tfs2**	0.03
OV	chr6	116278774	Missense_Mutation	NA	T353S	0.25
PAAD	chr6	116279618	Silent	novel	P71P	0.07
PRAD	chr6	116279889	5'UTR	novel		0.26
READ	chr6	116278912	Missense_Mutation	novel	L307V	0.46
SARC	chr6	116279542	Missense_Mutation	novel	G97R	0.13
SKCM	chr6	116278886	Silent	NA	P315P	0.26
SKCM	chr6	116278541	Silent	NA	R430R	0.23
SKCM	chr6	116278437	3'UTR	novel		0.39
SKCM	chr6	116279895	5'UTR	novel		0.5
SKCM	chr6	116279468	Silent	novel	L121L	0.44
STAD	chr6	116278642	Nonsense_Mutation	novel	K397*	0.26
STAD	chr6	116279463	Frame_Shift_Del	NA	*K123Rfs10**	0.13
STAD	chr6	116278923	Missense_Mutation	NA	Y303C	0.04
STAD	chr6	116279346	Missense_Mutation	novel	T162I	0.35
STAD	chr6	116278829	Silent	NA	K334K	0.26
THCA	chr6	116279098	Nonsense_Mutation	NA	Q245*	0.36
UCEC	chr6	116277145	3'UTR	novel		0.33
UCEC	chr6	116279380	Missense_Mutation	NA	E151K	0.21
UCEC	chr6	116278934	Missense_Mutation	NA	E299D	0.14
UCEC	chr6	116279463	Missense_Mutation	NA	K123R	0.24
UCEC	chr6	116278541	Silent	NA	R430R	0.21
UCEC	chr6	116277154	3'UTR	rs192585221		0.21
UCEC	chr6	116278650	Missense_Mutation	rs745484190	E394G	0.36
UCEC	chr6	116279446	Nonsense_Mutation	novel	E129*	0.38
UCEC	chr6	116279666	Missense_Mutation	novel	E55D	0.58
UCEC	chr6	116277103	3'UTR	novel		0.35
UCEC	chr6	116278658	Missense_Mutation	novel	K391N	0.31
UCEC	chr6	116278759	Missense_Mutation	novel	R358C	0.05
UCEC	chr6	116277391	3'UTR	novel		0.18
UCEC	chr6	116277405	3'UTR	novel		0.48
UCEC	chr6	116279391	Missense_Mutation	novel	G147E	0.12
UCEC	chr6	116279393	Silent	novel	A146A	0.12
UCEC	chr6	116278716	Missense_Mutation	NA	D372G	0.13
UCEC	chr6	116279678	Missense_Mutation	novel	E51D	0.36
UCEC	chr6	116279254	Missense_Mutation	NA	E193K	0.22
UCEC	chr6	116279031	Missense_Mutation	novel	R267Q	0.3
UCEC	chr6	116277146	3'UTR	novel		0.53
UCEC	chr6	116279837	5'UTR	novel		0.42
UCEC	chr6	116277220	3'UTR	novel		0.35

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BLCA	DEL	0.375	3.4915e-05
DLBC	DEL	0.2708	0.00052595
ESCA	DEL	0.212	0.036953
GBM	DEL	0.2149	1.056e-05
KIRC	DEL	0.233	7.439e-11
LGG	DEL	0.1404	0.0054594
LUAD	DEL	0.4167	0.0021365
MESO	DEL	0.4368	0.05642
PAAD	DEL	0.3587	0.11274
SKCM	DEL	0.5341	1.5442e-06
STAD	DEL	0.1315	0.0044196
THYM	DEL	0.1301	0.10691

Survival Analysis

Cancer	P-value	Q-value
MESO	0.00015	Kaplan-Meier Survival Analysis
ACC	0.0041	Kaplan-Meier Survival Analysis
HNSC	0.046	Kaplan-Meier Survival Analysis
SKCM	0.018	Kaplan-Meier Survival Analysis
BRCA	0.038	Kaplan-Meier Survival Analysis
KIRP	0.023	Kaplan-Meier Survival Analysis
PAAD	0.00017	Kaplan-Meier Survival Analysis
DLBC	0.039	Kaplan-Meier Survival Analysis
LGG	0.0001	Kaplan-Meier Survival Analysis
LUAD	0.022	Kaplan-Meier Survival Analysis
UVM	0.015	Kaplan-Meier Survival Analysis
OV	0.0098	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Expression

Transcripts

Gene Model

PPI

Gene Ontology

Description

Ensembl ID: ENSG00000189241 (Gene tree)
Gene ID: 7259
Gene Symbol: TSPYL1
Alias: TSPYL
Full Name: TSPY like 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 5,259 bases
Position: chr6:116,274,859-116,280,117
Accession: 12382
RBP type: non-canonical RBP
Summary: The protein encoded by this gene is found in the nucleolus and is similar to that of a family of genes on the Y-chromosome. This gene is intronless. Defects in this gene are a cause of sudden infant death with dysgenesis of the testes syndrome (SIDDT). [provided by RefSeq, Dec 2009]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000368608	TSPYL1-201	3326	-	ENSP00000357597	437 (aa)	-	Q9H0U9

Gene Model

Click here to download ENSG00000189241's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000189241's network

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005634	nucleus	-	IDA	Component
GO:0005730	nucleolus	-	IDA	Component
GO:0006334	nucleosome assembly	-	IEA	Process
GO:0008150	biological_process	-	ND	Process
GO:0019899	enzyme binding	23382074.	IPI	Function

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Expression

Transcripts

Gene Model

PPI

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.