15665816 | Inhibition of histone deacetylase 2 increases apoptosis and p21Cip1/WAF1 expression, independent of histone deacetylase 1. | Cell Death Differ | 2005 Apr | Huang BH | - |
23975430 | Significance of PELP1/HDAC2/miR-200 regulatory network in EMT and metastasis of breast cancer. | Oncogene | 2014 Jul 10 | Roy SS | doi: 10.1038/onc.2013.332 |
23440245 | A dual role for Hdac1: oncosuppressor in tumorigenesis, oncogene in tumor maintenance. | Blood | 2013 Apr 25 | Santoro F | doi: 10.1182/blood-2012-10-461988 |
21143702 | Expression of nuclear receptor corepressors and class I histone deacetylases in astrocytic gliomas. | Cancer Sci | 2011 Feb | Campos B | doi: 10.1111/j.1349-7006.2010.01792.x |
19416910 | Genetic dissection of histone deacetylase requirement in tumor cells. | Proc Natl Acad Sci U S A | 2009 May 12 | Haberland M | doi: 10.1073/pnas.0903139106 |
17935135 | Protein kinase CK2 is a key activator of histone deacetylase in hypoxia-associated tumors. | Int J Cancer | 2008 Jan 15 | Pluemsampant S | - |
25605253 | Selective inhibition of histone deacetylase 2 induces p53-dependent survivin downregulation through MDM2 proteasomal degradation. | Oncotarget | 2015 Sep 22 | Seo SK | doi: 10.18632/oncotarget.3100. |
21527555 | Physical association of HDAC1 and HDAC2 with p63 mediates transcriptional repression and tumor maintenance in squamous cell carcinoma. | Cancer Res | 2011 Jul 1 | Ramsey MR | doi: 10.1158/0008-5472.CAN-11-0046 |
20398369 | HDAC2 attenuates TRAIL-induced apoptosis of pancreatic cancer cells. | Mol Cancer | 2010 Apr 16 | Sch??ler S | doi: 10.1186/1476-4598-9-80. |
22641068 | Histone deacetylases activate hepatocyte growth factor signaling by repressing microRNA-449 in hepatocellular carcinoma cells. | Gastroenterology | 2012 Sep | Buurman R | doi: 10.1053/j.gastro.2012.05.033 |
26729194 | p21 and CK2 interaction-mediated HDAC2 phosphorylation modulates KLF4 acetylation to regulate bladder cancer cell proliferation. | Tumour Biol | 2016 Jun | Jia ZM | doi: 10.1007/s13277-015-4618-1 |
29333444 | MicroRNA-31 Function as a Suppressor Was Regulated by Epigenetic Mechanisms in Gastric Cancer. | Biomed Res Int | 2017 | Wei J | doi: 10.1155/2017/5348490 |
18212746 | Histone deacetylases 1, 2 and 3 are highly expressed in prostate cancer and HDAC2 expression is associated with shorter PSA relapse time after radical prostatectomy. | Br J Cancer | 2008 Feb 12 | Weichert W | doi: 10.1038/sj.bjc.6604199 |
30250993 | Expression profiles of histone modification genes in gastric cancer progression. | Mol Biol Rep | 2018 Dec | Orenay-Boyacioglu S | doi: 10.1007/s11033-018-4389-z |
19099586 | Class I histone deacetylases 1, 2 and 3 are highly expressed in renal cell cancer. | BMC Cancer | 2008 Dec 19 | Fritzsche FR | doi: 10.1186/1471-2407-8-381. |
23110995 | X-radiation inhibits histone deacetylase 1 and 2, upregulates Axin expression and induces apoptosis in non-small cell lung cancer. | Radiat Oncol | 2012 Oct 31 | Han Y | doi: 10.1186/1748-717X-7-183. |
24218540 | Chemopreventive effects of an HDAC2-selective inhibitor on rat colon carcinogenesis and APCmin/+ mouse intestinal tumorigenesis. | J Pharmacol Exp Ther | 2014 Jan | Ravillah D | doi: 10.1124/jpet.113.208645 |
18408217 | Lysophosphatidic acid protects cancer cells from histone deacetylase (HDAC) inhibitor-induced apoptosis through activation of HDAC. | J Biol Chem | 2008 Jun 13 | Ishdorj G | doi: 10.1074/jbc.M710177200 |
23251689 | Class I and class II histone deacetylases are potential therapeutic targets for treating pancreatic cancer. | PLoS One | 2012 | Wang G | doi: 10.1371/journal.pone.0052095 |
17786334 | Expression profile of class I histone deacetylases in human cancer tissues. | Oncol Rep | 2007 Oct | Nakagawa M | - |
19724929 | Efficacy of MS-275, a selective inhibitor of class I histone deacetylases, in human colon cancer models. | Int J Oncol | 2009 Oct | Bracker TU | - |
22492270 | HDAC2 overexpression confers oncogenic potential to human lung cancer cells by deregulating expression of apoptosis and cell cycle proteins. | J Cell Biochem | 2012 Jun | Jung KH | doi: 10.1002/jcb.24090. |
23544610 | HDAC inhibitor trichostatin A suppresses esophageal squamous cell carcinoma metastasis through HADC2 reduced MMP-2/9. | Clin Invest Med | 2013 Apr 1 | Wang F | - |
20190809 | Coordination of PAD4 and HDAC2 in the regulation of p53-target gene expression. | Oncogene | 2010 May 27 | Li P | doi: 10.1038/onc.2010.51 |
26683361 | The role of HDAC2 in chromatin remodelling and response to chemotherapy in ovarian cancer. | Oncotarget | 2016 Jan 26 | Huang R | doi: 10.18632/oncotarget.6618. |
20585871 | Histone deacetylase (HDAC) 1 and 2 expression and chemotherapy in gastric cancer. | Ann Surg Oncol | 2010 Dec | Mutze K | doi: 10.1245/s10434-010-1182-1 |
23926105 | Loss of epigenetic Kruppel-like factor 4 histone deacetylase (KLF-4-HDAC)-mediated transcriptional suppression is crucial in increasing vascular endothelial growth factor (VEGF) expression in breast cancer. | J Biol Chem | 2013 Sep 20 | Ray A | doi: 10.1074/jbc.M113.481184 |
19912635 | High class I HDAC activity and expression are associated with RelA/p65 activation in pancreatic cancer in vitro and in vivo. | BMC Cancer | 2009 Nov 13 | Lehmann A | doi: 10.1186/1471-2407-9-395. |
24390319 | VPA inhibits renal cancer cell migration by targeting HDAC2 and down-regulating HIF-1α. | Mol Biol Rep | 2014 Mar | Yang FQ | doi: 10.1007/s11033-013-2996-2 |
19383825 | Protein acetylation and histone deacetylase expression associated with malignant breast cancer progression. | Clin Cancer Res | 2009 May 1 | Suzuki J | doi: 10.1158/1078-0432.CCR-08-2319 |
22944197 | Changes in histone deacetylase (HDAC) expression patterns and activity of HDAC inhibitors in urothelial cancers. | Urol Oncol | 2013 Nov | Niegisch G | doi: 10.1016/j.urolonc.2012.06.015 |
26846508 | Histone deacetylase 2 regulates doxorubicin (Dox) sensitivity of colorectal cancer cells by targeting ABCB1 transcription. | Cancer Chemother Pharmacol | 2016 Mar | Ye P | doi: 10.1007/s00280-016-2979-9 |
18347167 | Class I histone deacetylase expression has independent prognostic impact in human colorectal cancer: specific role of class I histone deacetylases in vitro and in vivo. | Clin Cancer Res | 2008 Mar 15 | Weichert W | doi: 10.1158/1078-0432.CCR-07-0990. |
25942572 | Histone deacetylases 1 and 2 regulate DNA replication and DNA repair: potential targets for genome stability-mechanism-based therapeutics for a subset of cancers. | Cell Cycle | 2015 | Bhaskara S | doi: 10.1080/15384101.2015.1042634. |
15144953 | Induction of HDAC2 expression upon loss of APC in colorectal tumorigenesis. | Cancer Cell | 2004 May | Zhu P | - |
26352599 | HDAC1 and HDAC2 independently predict mortality in hepatocellular carcinoma by a competing risk regression model in a Southeast Asian population. | Oncol Rep | 2015 Nov | Ler SY | doi: 10.3892/or.2015.4263 |
28839465 | FKBP3 Promotes Proliferation of Non-Small Cell Lung Cancer Cells through Regulating Sp1/HDAC2/p27. | Theranostics | 2017 Jul 22 | Zhu W | doi: 10.7150/thno.18067 |