EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
26722446	MicroRNA-214 targets PCBP2 to suppress the proliferation and growth of glioma cells.	Int J Clin Exp Pathol	2015 Oct 1	Tang SL	-
24607900	The histone deacetylase SIRT6 suppresses the expression of the RNA-binding protein PCBP2 in glioma.	Biochem Biophys Res Commun	2014 Mar 28	Chen X	doi: 10.1016/j.bbrc.2014.02.116
24796666	The RNA-binding protein PCBP2 facilitates gastric carcinoma growth by targeting miR-34a.	Biochem Biophys Res Commun	2014 Jun 13	Hu CE	doi: 10.1016/j.bbrc.2014.04.124
12011088	Novel binding of HuR and poly(C)-binding protein to a conserved UC-rich motif within the 3'-untranslated region of the androgen receptor messenger RNA.	J Biol Chem	2002 Jul 26	Yeap BB	-
17145707	Selection and cloning of poly(rC)-binding protein 2 and Raf kinase inhibitor protein RNA activators of 2',5'-oligoadenylate synthetase from prostate cancer cells.	Nucleic Acids Res	2006	Molinaro RJ	-
17219427	HnRNP E2 is downregulated in human oral cancer cells and the overexpression of hnRNP E2 induces apoptosis.	Mol Carcinog	2007 Mar	Roychoudhury P	-

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr12	53464822	Silent	NA	L218L	0.26
BLCA	chr12	53467340	Intron	novel		0.5
BRCA	chr12	53459283	Missense_Mutation	NA	S85R	0.38
BRCA	chr12	53461121	Frame_Shift_Ins	NA	*Q161Hfs61**	0.46
BRCA	chr12	53455490	Silent	NA	E41E	0.32
BRCA	chr12	53461027	Missense_Mutation	novel	Q130E	0.05
BRCA	chr12	53461061	Nonsense_Mutation	NA	S141*	0.22
BRCA	chr12	53467423	Intron	novel		0.1
BRCA	chr12	53454858	Missense_Mutation	NA	M20V	0.31	KH_1
CESC	chr12	53460808	Intron	novel		0.4
CESC	chr12	53462500	Missense_Mutation	NA	P175L	0.49
CESC	chr12	53454815	Silent	novel	V5V	0.1
COAD	chr12	53460949	Intron	NA		0.06
COAD	chr12	53464773	Frame_Shift_Del	NA	*T202Kfs26**	0.32
COAD	chr12	53467352	Intron	novel		0.15
ESCA	chr12	53479575	3'UTR	novel		0.25
ESCA	chr12	53479549	3'UTR	novel		0.31
GBM	chr12	53471771	Missense_Mutation	novel	A342V	0.04
GBM	chr12	53455939	Silent	novel	L61L	0.17
GBM	chr12	53459355	Missense_Mutation	novel	C109W	0.07
HNSC	chr12	53455935	Silent	novel	I59I	0.27
HNSC	chr12	53455999	Nonsense_Mutation	novel	E81*	0.08
HNSC	chr12	53467299	Splice_Region	novel		0.42
HNSC	chr12	53461014	Splice_Site	novel	X126_splice	0.28
HNSC	chr12	53462493	Frame_Shift_Ins	rs776329515	*K176Efs46**	0.49
HNSC	chr12	53461009	Splice_Region	novel		0.15
KIRC	chr12	53459335	Missense_Mutation	NA	V103M	0.36
KIRP	chr12	53454830	Missense_Mutation	novel	L10F	0.24
LGG	chr12	53467842	Nonsense_Mutation	novel	W279*	0.06
LGG	chr12	53471660	Missense_Mutation	NA	R305H	0.12
LGG	chr12	53455365	Missense_Mutation	novel	G30R	0.32	KH_1
LIHC	chr12	53479494	3'UTR	novel		0.29
LUAD	chr12	53459318	Missense_Mutation	rs111807426	P97L	0.29
LUAD	chr12	53455924	Missense_Mutation	NA	E56Q	0.07
LUAD	chr12	53455488	Nonsense_Mutation	novel	E41*	0.09	KH_1
LUSC	chr12	53479493	3'UTR	novel		0.25
LUSC	chr12	53459378	Missense_Mutation	NA	G117V	0.46
MESO	chr12	53467368	Intron	novel		0.3
OV	chr12	53467283	Silent	rs75582496	T263T	0.2
OV	chr12	53455469	Frame_Shift_Ins	novel	*S35Nfs48**	0.04	KH_1
OV	chr12	53455343	Splice_Site	novel	X24_splice	0.28
OV	chr12	53479456	3'UTR	novel		0.06
PAAD	chr12	53467285	Missense_Mutation	novel	G264E	0.19
PAAD	chr12	53479442	Silent	novel	*366*	0.23
PRAD	chr12	53467270	Missense_Mutation	NA	T259M	0.33
PRAD	chr12	53471659	Missense_Mutation	novel	R305C	0.46
READ	chr12	53460973	Intron	novel		0.32
READ	chr12	53461070	Missense_Mutation	NA	R144Q	0.59
READ	chr12	53479420	Missense_Mutation	NA	T359M	0.29
SKCM	chr12	53467387	Intron	novel		0.22
SKCM	chr12	53459291	Missense_Mutation	NA	T88I	0.25
SKCM	chr12	53462565	Nonsense_Mutation	NA	Q197*	0.15
SKCM	chr12	53454803	Translation_Start_Site	NA	M1?	0.29
SKCM	chr12	53461001	Intron	novel		0.41
SKCM	chr12	53471686	Missense_Mutation	NA	R314C	0.12
SKCM	chr12	53459285	Missense_Mutation	NA	S86Y	0.3
SKCM	chr12	53467387	Intron	novel		0.59
SKCM	chr12	53461100	Missense_Mutation	NA	S154F	0.57
STAD	chr12	53459319	Silent	rs571129099	P97P	0.15
STAD	chr12	53460987	Intron	novel		0.06
STAD	chr12	53464776	Missense_Mutation	novel	G203D	0.52
STAD	chr12	53467270	Missense_Mutation	NA	T259M	0.43
STAD	chr12	53455372	Splice_Site	NA	X31_splice	0.35
STAD	chr12	53461080	Frame_Shift_Del	novel	*I148Cfs9**	0.32
THYM	chr12	53471660	Missense_Mutation	NA	R305H	0.08
UCEC	chr12	53467298	Splice_Region	novel		0.52
UCEC	chr12	53467426	Intron	novel		0.45
UCEC	chr12	53455486	Missense_Mutation	NA	R40H	0.39	KH_1
UCEC	chr12	53465949	Silent	novel	G234G	0.06
UCEC	chr12	53462499	Missense_Mutation	novel	P175T	0.44
UCEC	chr12	53455895	Missense_Mutation	NA	R46H	0.08	KH_1
UCEC	chr12	53479524	3'UTR	novel		0.06
UCEC	chr12	53462484	Missense_Mutation	NA	L170I	0.24
UCEC	chr12	53471764	Missense_Mutation	novel	S340T	0.29
UCEC	chr12	53467815	Silent	novel	S270S	0.53
UCEC	chr12	53460772	Intron	novel		0.44
UCEC	chr12	53460841	Intron	novel		0.29
UCEC	chr12	53462493	Frame_Shift_Ins	rs776329515	*K176Efs46**	0.39
UCEC	chr12	53479421	Silent	rs756725675	T359T	0.54
UCEC	chr12	53464810	Silent	rs778927182	P214P	0.39
UCEC	chr12	53461133	Missense_Mutation	novel	V165A	0.2
UCEC	chr12	53471749	Missense_Mutation	NA	V335F	0.13
UCEC	chr12	53455895	Missense_Mutation	NA	R46H	0.41	KH_1
UCEC	chr12	53462493	Frame_Shift_Ins	rs776329515	*K176Efs46**	0.38
UCEC	chr12	53471703	Silent	rs759662942	A319A	0.33
UCEC	chr12	53471663	Missense_Mutation	novel	Q306R	0.37
UCEC	chr12	53462494	Frame_Shift_Del	NA	*P175Rfs4**	0.45
UCEC	chr12	53468807	Missense_Mutation	NA	S289Y	0.3
UCEC	chr12	53460909	Intron	novel		0.16
UCEC	chr12	53460917	Intron	novel		0.49
UCEC	chr12	53455895	Missense_Mutation	NA	R46H	0.36	KH_1

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
DLBC	AMP	0.1875	0.085003
READ	DEL	0.0667	0.064633
STAD	DEL	0.0907	0.22179

Survival Analysis

Cancer	P-value	Q-value
THYM	0.0087	Kaplan-Meier Survival Analysis
KIRC	0.017	Kaplan-Meier Survival Analysis
SARC	0.047	Kaplan-Meier Survival Analysis
ACC	0.00012	Kaplan-Meier Survival Analysis
UCS	0.0024	Kaplan-Meier Survival Analysis
HNSC	0.021	Kaplan-Meier Survival Analysis
LUSC	0.019	Kaplan-Meier Survival Analysis
KIRP	0.023	Kaplan-Meier Survival Analysis
PAAD	0.012	Kaplan-Meier Survival Analysis
LAML	0.027	Kaplan-Meier Survival Analysis
UCEC	0.022	Kaplan-Meier Survival Analysis
GBM	0.018	Kaplan-Meier Survival Analysis
LIHC	0.0001	Kaplan-Meier Survival Analysis
LUAD	0.025	Kaplan-Meier Survival Analysis
UVM	0.00011	Kaplan-Meier Survival Analysis
OV	0.0014	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

PRI

Literatures

Expression

Transcripts

Gene Model

Pathways

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000197111 (Gene tree)
Gene ID: 5094
Gene Symbol: PCBP2
Alias: HNRPE2|hnRNP-E2|HNRNPE2
Full Name: poly(rC) binding protein 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 29,061 bases
Position: chr12:53,452,102-53,481,162
Accession: 8648
RBP type: canonical RBP
Summary: The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. This gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2018]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000388008	KH_1	PF00013.29	2.7e-49	1	3
ENSP00000388008	KH_1	PF00013.29	2.7e-49	2	3
ENSP00000388008	KH_1	PF00013.29	2.7e-49	3	3
ENSP00000390304	KH_1	PF00013.29	2.7e-49	1	3
ENSP00000390304	KH_1	PF00013.29	2.7e-49	2	3
ENSP00000390304	KH_1	PF00013.29	2.7e-49	3	3
ENSP00000447670	KH_1	PF00013.29	2.9e-49	1	3
ENSP00000447670	KH_1	PF00013.29	2.9e-49	2	3
ENSP00000447670	KH_1	PF00013.29	2.9e-49	3	3
ENSP00000449070	KH_1	PF00013.29	2.9e-49	1	3
ENSP00000449070	KH_1	PF00013.29	2.9e-49	2	3
ENSP00000449070	KH_1	PF00013.29	2.9e-49	3	3
ENSP00000352228	KH_1	PF00013.29	3.3e-49	1	3
ENSP00000352228	KH_1	PF00013.29	3.3e-49	2	3
ENSP00000352228	KH_1	PF00013.29	3.3e-49	3	3
ENSP00000394116	KH_1	PF00013.29	3.5e-49	1	3
ENSP00000394116	KH_1	PF00013.29	3.5e-49	2	3
ENSP00000394116	KH_1	PF00013.29	3.5e-49	3	3
ENSP00000449062	KH_1	PF00013.29	3.5e-49	1	3
ENSP00000449062	KH_1	PF00013.29	3.5e-49	2	3
ENSP00000449062	KH_1	PF00013.29	3.5e-49	3	3
ENSP00000448927	KH_1	PF00013.29	5e-49	1	3
ENSP00000448927	KH_1	PF00013.29	5e-49	2	3
ENSP00000448927	KH_1	PF00013.29	5e-49	3	3
ENSP00000448762	KH_1	PF00013.29	5e-49	1	3
ENSP00000448762	KH_1	PF00013.29	5e-49	2	3
ENSP00000448762	KH_1	PF00013.29	5e-49	3	3
ENSP00000408949	KH_1	PF00013.29	5.2e-49	1	3
ENSP00000408949	KH_1	PF00013.29	5.2e-49	2	3
ENSP00000408949	KH_1	PF00013.29	5.2e-49	3	3
ENSP00000352438	KH_1	PF00013.29	5.3e-49	1	3
ENSP00000352438	KH_1	PF00013.29	5.3e-49	2	3
ENSP00000352438	KH_1	PF00013.29	5.3e-49	3	3
ENSP00000456412	KH_1	PF00013.29	5.9e-48	1	3
ENSP00000456412	KH_1	PF00013.29	5.9e-48	2	3
ENSP00000456412	KH_1	PF00013.29	5.9e-48	3	3
ENSP00000446601	KH_1	PF00013.29	6.5e-31	1	2
ENSP00000446601	KH_1	PF00013.29	6.5e-31	2	2
ENSP00000448847	KH_1	PF00013.29	1.3e-27	1	2
ENSP00000448847	KH_1	PF00013.29	1.3e-27	2	2
ENSP00000448672	KH_1	PF00013.29	6.6e-21	1	1
ENSP00000456842	KH_1	PF00013.29	6.6e-18	1	1
ENSP00000448079	KH_1	PF00013.29	6.8e-12	1	1
ENSP00000447670	KH_2	PF07650.17	3e-14	1	1
ENSP00000449070	KH_2	PF07650.17	3e-14	1	1
ENSP00000394116	KH_2	PF07650.17	3.5e-14	1	1
ENSP00000449062	KH_2	PF07650.17	3.5e-14	1	1
ENSP00000388008	KH_2	PF07650.17	3.5e-14	1	1
ENSP00000390304	KH_2	PF07650.17	3.5e-14	1	1
ENSP00000352228	KH_2	PF07650.17	4.2e-14	1	1
ENSP00000408949	KH_2	PF07650.17	4.8e-14	1	1
ENSP00000352438	KH_2	PF07650.17	5.3e-14	1	1
ENSP00000448927	KH_2	PF07650.17	5.8e-14	1	1
ENSP00000448762	KH_2	PF07650.17	6.4e-14	1	1
ENSP00000456412	KH_2	PF07650.17	7.5e-14	1	1
ENSP00000446601	KH_2	PF07650.17	3.4e-11	1	1
ENSP00000448847	KH_2	PF07650.17	2.6e-08	1	1
ENSP00000448079	KH_2	PF07650.17	0.00047	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Protein-RNA interaction（RNA-Binding Site）

Click here to download all RNA binding sites

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
18512313	[Targeted blockage of RNA binding protein E2 by decoy RNA induces the granulocytic differentiation of K562 cells].	Zhonghua Xue Ye Xue Za Zhi	2008 Jan	Chen XM	-
10608888	The N-terminal K homology domain of the poly(rC)-binding protein is a major determinant for binding to the poliovirus 5'-untranslated region and acts as an inhibitor of viral translation.	J Biol Chem	1999 Dec 31	Silvera D	-
15247434	Multimerization of poly(rC) binding protein 2 is required for translation initiation mediated by a viral IRES.	RNA	2004 Aug	Bedard KM	-
10507322	Rhinovirus 2A proteinase mediated stimulation of rhinovirus RNA translation is additive to the stimulation effected by cellular RNA binding proteins.	Virus Res	1999 Aug	Hunt SL	-
8855318	Poly(rC) binding protein 2 binds to stem-loop IV of the poliovirus RNA 5' noncoding region: identification by automated liquid chromatography-tandem mass spectrometry.	Proc Natl Acad Sci U S A	1996 Oct 1	Blyn LB	-
25717101	Cellular STAT3 functions via PCBP2 to restrain Epstein-Barr Virus lytic activation in B lymphocytes.	J Virol	2015 May	Koganti S	doi: 10.1128/JVI.00121-15
24371074	Inhibition of poliovirus-induced cleavage of cellular protein PCBP2 reduces the levels of viral RNA replication.	J Virol	2014 Mar	Chase AJ	doi: 10.1128/JVI.02503-13
29744291	Poly(rC) binding protein 2 (PCBP2) promotes the viability of human gastric cancer cells by regulating CDK2.	FEBS Open Bio	2018 Mar 22	Chen C	doi: 10.1002/2211-5463.12408
31010886	eIF4G2 balances its own mRNA translation via a PCBP2-based feedback loop.	RNA	2019 Jul	Smirnova VV	doi: 10.1261/rna.065623.118
9811700	Interaction of poly(rC) binding protein 2 with the 5' noncoding region of hepatitis A virus RNA and its effects on translation.	J Virol	1998 Dec	Graff J	-
20519371	The poly(c)-binding protein-1 regulates expression of the androgen receptor.	Endocrinology	2010 Aug	Cloke B	doi: 10.1210//en.2009-1264
23776146	Specificity factors in cytoplasmic polyadenylation.	Wiley Interdiscip Rev RNA	2013 Jul-Aug	Charlesworth A	doi: 10.1002/wrna.1171.
7556077	Identification of two KH domain proteins in the alpha-globin mRNP stability complex.	EMBO J	1995 Sep 1	Kiledjian M	-
9326487	Poly (rC) binding protein 2 forms a ternary complex with the 5'-terminal sequences of poliovirus RNA and the viral 3CD proteinase.	RNA	1997 Oct	Parsley TB	-
12476304	Post-transcriptional mechanisms in BCR/ABL leukemogenesis: role of shuttling RNA-binding proteins.	Oncogene	2002 Dec 9	Perrotti D	-
12414943	Distinct poly(rC) binding protein KH domain determinants for poliovirus translation initiation and viral RNA replication.	J Virol	2002 Dec	Walter BL	-
23077311	Induction of stress granule-like structures in vesicular stomatitis virus-infected cells.	J Virol	2013 Jan	Dinh PX	doi: 10.1128/JVI.02305-12
18252259	Protein-RNA tethering: the role of poly(C) binding protein 2 in poliovirus RNA replication.	Virology	2008 May 10	Spear A	doi: 10.1016/j.virol.2007.12.039
17475908	High levels of the BCR/ABL oncoprotein are required for the MAPK-hnRNP-E2 dependent suppression of C/EBPalpha-driven myeloid differentiation.	Blood	2007 Aug 1	Chang JS	-
17363515	From mRNA metabolism to cancer therapy: chronic myelogenous leukemia shows the way.	Clin Cancer Res	2007 Mar 15	Perrotti D	-
17327219	The myotonic dystrophy type 2 protein ZNF9 is part of an ITAF complex that promotes cap-independent translation.	Mol Cell Proteomics	2007 Jun	Gerbasi VR	-
17183366	A nucleo-cytoplasmic SR protein functions in viral IRES-mediated translation initiation.	EMBO J	2007 Jan 24	Bedard KM	-
24998228	Ribotrap analysis of proteins associated with FHL3 3'untranslated region in glioma cells.	Chin Med Sci J	2014 Jun	Han W	-
24796666	The RNA-binding protein PCBP2 facilitates gastric carcinoma growth by targeting miR-34a.	Biochem Biophys Res Commun	2014 Jun 13	Hu CE	doi: 10.1016/j.bbrc.2014.04.124
24607900	The histone deacetylase SIRT6 suppresses the expression of the RNA-binding protein PCBP2 in glioma.	Biochem Biophys Res Commun	2014 Mar 28	Chen X	doi: 10.1016/j.bbrc.2014.02.116
24480778	Specific enrichment of the RNA-binding proteins PCBP1 and PCBP2 in chief cells of the murine gastric mucosa.	Gene Expr Patterns	2014 Mar	Ghanem LR	doi: 10.1016/j.gep.2014.01.004
23585479	RNA-binding protein PCBP2 modulates glioma growth by regulating FHL3.	J Clin Invest	2013 May	Han W	doi: 10.1172/JCI61820
26907686	RNA-binding Protein PCBP2 Regulates p73 Expression and p73-dependent Antioxidant Defense.	J Biol Chem	2016 Apr 29	Ren C	doi: 10.1074/jbc.M115.712125
26761212	Interplay between PCBP2 and miRNA modulates ARHGDIA expression and function in glioma migration and invasion.	Oncotarget	2016 Apr 12	Lin X	doi: 10.18632/oncotarget.6869.
26116532	The RNA-binding protein PCBP2 inhibits Ang II-induced hypertrophy of cardiomyocytes though promoting GPR56 mRNA degeneration.	Biochem Biophys Res Commun	2015 Aug 28	Zhang Y	doi: 10.1016/j.bbrc.2015.06.139
26002461	PCBP2 regulates hepatic insulin sensitivity via HIF-1α and STAT3 pathway in HepG2 cells.	Biochem Biophys Res Commun	2015 Jul 17-24	Xia N	doi: 10.1016/j.bbrc.2015.04.150
29335020	Ensemble genomic analysis in human lung tissue identifies novel genes for chronic obstructive pulmonary disease.	Hum Genomics	2018 Jan 15	Morrow JD	doi: 10.1186/s40246-018-0132-z.
11001936	Nuclear inclusions in oculopharyngeal muscular dystrophy consist of poly(A) binding protein 2 aggregates which sequester poly(A) RNA.	Hum Mol Genet	2000 Sep 22	Calado A	-
16831266	[Effect and possible mechanism of HnRNP E2 decoy RNA on proliferation of K562 leukemia cells].	Ai Zheng	2006 Jul	Chen XM	-
15331611	Specific recognition of the C-rich strand of human telomeric DNA and the RNA template of human telomerase by the first KH domain of human poly(C)-binding protein-2.	J Biol Chem	2004 Nov 12	Du Z	-
24719423	hnRNP L and NF90 interact with hepatitis C virus 5'-terminal untranslated RNA and promote efficient replication.	J Virol	2014 Jul	Li Y	doi: 10.1128/JVI.00225-14
28539455	Functional Consequences of RNA 5'-Terminal Deletions on Coxsackievirus B3 RNA Replication and Ribonucleoprotein Complex Formation.	J Virol	2017 Jul 27	Leveque N	doi: 10.1128/JVI.00423-17
9223526	Requirement of poly(rC) binding protein 2 for translation of poliovirus RNA.	J Virol	1997 Aug	Blyn LB	-
19446305	Altered interactions between stem-loop IV within the 5' noncoding region of coxsackievirus RNA and poly(rC) binding protein 2: effects on IRES-mediated translation and viral infectivity.	Virology	2009 Jun 20	Sean P	doi: 10.1016/j.virol.2009.03.012
18929541	Interaction of poly(rC)-binding protein 2 domains KH1 and KH3 with coxsackievirus RNA.	Biochem Biophys Res Commun	2008 Dec 12	Zell R	doi: 10.1016/j.bbrc.2008.09.156
17967440	RNA interaction and cleavage of poly(C)-binding protein 2 by hepatitis A virus protease.	Biochem Biophys Res Commun	2007 Dec 28	Zhang B	-
17145707	Selection and cloning of poly(rC)-binding protein 2 and Raf kinase inhibitor protein RNA activators of 2',5'-oligoadenylate synthetase from prostate cancer cells.	Nucleic Acids Res	2006	Molinaro RJ	-
22366449	Inhibition of mRNA maturation in trypanosomes causes the formation of novel foci at the nuclear periphery containing cytoplasmic regulators of mRNA fate.	J Cell Sci	2012 Jun 15	Kramer S	doi: 10.1242/jcs.099275
21632751	Poly(C)-binding protein 2 interacts with sequences required for viral replication in the hepatitis C virus (HCV) 5' untranslated region and directs HCV RNA replication through circularizing the viral genome.	J Virol	2011 Aug	Wang L	doi: 10.1128/JVI.00339-11
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29327729	H5N1 influenza virus-specific miRNA-like small RNA increases cytokine production and mouse mortality via targeting poly(rC)-binding protein 2.	Cell Res	2018 Feb	Li X	doi: 10.1038/cr.2018.3
30925703	A Combined ELONA-(RT)qPCR Approach for Characterizing DNA and RNA Aptamers Selected against PCBP-2.	Molecules	2019 Mar 28	Moreno M	doi: 10.3390/molecules24071213.
15134450	NMR structures of loop B RNAs from the stem-loop IV domain of the enterovirus internal ribosome entry site: a single C to U substitution drastically changes the shape and flexibility of RNA.	Biochemistry	2004 May 18	Du Z	-
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18054780	Dynamic endogenous association of neurofilament mRNAs with K-homology domain ribonucleoproteins in developing cerebral cortex.	Brain Res	2008 Jan 16	Thyagarajan A	-
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Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000550585	PCBP2-218	2543	-	ENSP00000454797	112 (aa)	-	H3BND9
ENST00000549863	PCBP2-215	1619	-	ENSP00000447670	321 (aa)	-	F8VZX2
ENST00000550910	PCBP2-220	449	-	-	- (aa)	-	-
ENST00000437231	PCBP2-203	3026	-	ENSP00000390304	318 (aa)	-	Q15366
ENST00000549272	PCBP2-214	445	-	-	- (aa)	-	-
ENST00000546652	PCBP2-208	823	-	ENSP00000447068	202 (aa)	-	F8W1G6
ENST00000562264	PCBP2-226	1145	-	ENSP00000456412	301 (aa)	-	H3BRU6
ENST00000359282	PCBP2-201	1730	-	ENSP00000352228	331 (aa)	-	Q15366
ENST00000553064	PCBP2-225	1786	-	ENSP00000448672	310 (aa)	-	F8VRH0
ENST00000547987	PCBP2-211	681	-	-	- (aa)	-	-
ENST00000552296	PCBP2-222	1342	-	ENSP00000448927	361 (aa)	-	Q15366
ENST00000552980	PCBP2-224	527	-	ENSP00000456795	36 (aa)	-	H3BSP4
ENST00000439930	PCBP2-204	1296	-	ENSP00000408949	365 (aa)	-	Q15366
ENST00000359462	PCBP2-202	1814	-	ENSP00000352438	366 (aa)	-	Q15366
ENST00000548190	PCBP2-212	581	-	-	- (aa)	-	-
ENST00000547859	PCBP2-210	1919	-	ENSP00000456842	184 (aa)	-	H3BSS4
ENST00000550733	PCBP2-219	754	-	-	- (aa)	-	-
ENST00000455667	PCBP2-206	2741	-	ENSP00000388008	318 (aa)	-	Q15366
ENST00000550192	PCBP2-216	734	-	ENSP00000448079	64 (aa)	-	F8VTZ0
ENST00000551104	PCBP2-221	681	-	ENSP00000446601	158 (aa)	-	F8W0G4
ENST00000547048	PCBP2-209	1696	-	-	- (aa)	-	-
ENST00000552819	PCBP2-223	1418	-	ENSP00000449070	322 (aa)	-	Q15366
ENST00000550520	PCBP2-217	753	-	ENSP00000448847	160 (aa)	-	F8VXH9
ENST00000546463	PCBP2-207	1457	-	ENSP00000448762	362 (aa)	-	Q15366
ENST00000447282	PCBP2-205	3077	-	ENSP00000394116	335 (aa)	-	Q15366
ENST00000548933	PCBP2-213	1202	-	ENSP00000449062	335 (aa)	-	Q15366

Gene Model

Click here to download ENSG00000197111's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa04216	Ferroptosis	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000197111's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000197111	PCBP2	89	36.486	ENSG00000104967	NOVA2	50	41.096
ENSG00000197111	PCBP2	100	93.038	ENSG00000169564	PCBP1	100	82.834
ENSG00000197111	PCBP2	84	34.437	ENSG00000107164	FUBP3	79	30.201
ENSG00000197111	PCBP2	94	69.799	ENSG00000090097	PCBP4	92	70.130
ENSG00000197111	PCBP2	100	87.500	ENSG00000183570	PCBP3	91	84.177
ENSG00000197111	PCBP2	98	36.800	ENSG00000073792	IGF2BP2	68	35.075
ENSG00000197111	PCBP2	74	33.333	ENSG00000088247	KHSRP	99	34.247
ENSG00000197111	PCBP2	95	32.353	ENSG00000159217	IGF2BP1	57	34.646
ENSG00000197111	PCBP2	96	30.400	ENSG00000136231	IGF2BP3	61	30.400
ENSG00000197111	PCBP2	94	39.726	ENSG00000139910	NOVA1	71	35.135
ENSG00000197111	PCBP2	97	41.121	ENSG00000165119	HNRNPK	96	44.898

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000197111	PCBP2	100	98.438	ENSAPOG00000019824	PCBP2	93	94.937	Acanthochromis_polyacanthus
ENSG00000197111	PCBP2	100	93.750	ENSAPOG00000003089	pcbp2	100	88.679	Acanthochromis_polyacanthus
ENSG00000197111	PCBP2	100	100.000	ENSAMEG00000012520	PCBP2	97	92.308	Ailuropoda_melanoleuca
ENSG00000197111	PCBP2	100	88.889	ENSACIG00000000035	pcbp2	100	82.704	Amphilophus_citrinellus
ENSG00000197111	PCBP2	100	88.125	ENSACIG00000016893	PCBP2	93	88.125	Amphilophus_citrinellus
ENSG00000197111	PCBP2	100	98.438	ENSAOCG00000005296	PCBP2	93	94.937	Amphiprion_ocellaris
ENSG00000197111	PCBP2	100	93.750	ENSAOCG00000010959	pcbp2	100	88.679	Amphiprion_ocellaris
ENSG00000197111	PCBP2	100	98.438	ENSAPEG00000008226	PCBP2	93	94.937	Amphiprion_percula
ENSG00000197111	PCBP2	100	93.750	ENSAPEG00000017523	pcbp2	100	88.679	Amphiprion_percula
ENSG00000197111	PCBP2	100	98.438	ENSATEG00000025007	PCBP2	93	94.937	Anabas_testudineus
ENSG00000197111	PCBP2	100	92.188	ENSATEG00000019272	pcbp2	100	88.365	Anabas_testudineus
ENSG00000197111	PCBP2	100	100.000	ENSACAG00000000783	PCBP2	100	98.489	Anolis_carolinensis
ENSG00000197111	PCBP2	100	100.000	ENSANAG00000032275	PCBP2	100	100.000	Aotus_nancymaae
ENSG00000197111	PCBP2	100	98.438	ENSACLG00000018264	PCBP2	100	89.623	Astatotilapia_calliptera
ENSG00000197111	PCBP2	100	96.875	ENSAMXG00000016858	-	100	87.421	Astyanax_mexicanus
ENSG00000197111	PCBP2	100	98.438	ENSAMXG00000037819	pcbp2	100	89.937	Astyanax_mexicanus
ENSG00000197111	PCBP2	100	100.000	ENSBTAG00000020757	PCBP2	100	100.000	Bos_taurus
ENSG00000197111	PCBP2	100	100.000	ENSCJAG00000034075	-	93	98.113	Callithrix_jacchus
ENSG00000197111	PCBP2	100	100.000	ENSCJAG00000018590	-	100	100.000	Callithrix_jacchus
ENSG00000197111	PCBP2	100	100.000	ENSCAFG00000013587	-	100	96.855	Canis_familiaris
ENSG00000197111	PCBP2	100	100.000	ENSCAFG00000006821	-	100	100.000	Canis_familiaris
ENSG00000197111	PCBP2	97	93.617	ENSCAFG00020020983	-	100	93.617	Canis_lupus_dingo
ENSG00000197111	PCBP2	100	100.000	ENSCAFG00020004084	-	89	95.699	Canis_lupus_dingo
ENSG00000197111	PCBP2	100	100.000	ENSCHIG00000019895	PCBP2	100	100.000	Capra_hircus
ENSG00000197111	PCBP2	99	81.737	ENSTSYG00000028815	-	100	81.737	Carlito_syrichta
ENSG00000197111	PCBP2	100	100.000	ENSTSYG00000009771	PCBP2	100	100.000	Carlito_syrichta
ENSG00000197111	PCBP2	86	70.803	ENSCAPG00000012696	PCBP2	84	76.695	Cavia_aperea
ENSG00000197111	PCBP2	100	100.000	ENSCPOG00000000967	PCBP2	100	100.000	Cavia_porcellus
ENSG00000197111	PCBP2	100	100.000	ENSCCAG00000012038	PCBP2	100	100.000	Cebus_capucinus
ENSG00000197111	PCBP2	100	97.222	ENSCATG00000031513	-	100	74.792	Cercocebus_atys
ENSG00000197111	PCBP2	100	98.438	ENSCATG00000031376	-	100	91.900	Cercocebus_atys
ENSG00000197111	PCBP2	100	100.000	ENSCATG00000036013	PCBP2	100	100.000	Cercocebus_atys
ENSG00000197111	PCBP2	99	100.000	ENSCLAG00000012230	PCBP2	100	94.751	Chinchilla_lanigera
ENSG00000197111	PCBP2	99	90.446	ENSCLAG00000006163	-	100	84.677	Chinchilla_lanigera
ENSG00000197111	PCBP2	100	96.875	ENSCSAG00000017221	-	100	87.850	Chlorocebus_sabaeus
ENSG00000197111	PCBP2	100	98.408	ENSCSAG00000005487	-	86	98.408	Chlorocebus_sabaeus
ENSG00000197111	PCBP2	99	93.367	ENSCHOG00000012759	-	100	100.000	Choloepus_hoffmanni
ENSG00000197111	PCBP2	100	100.000	ENSCPBG00000001467	PCBP2	100	99.686	Chrysemys_picta_bellii
ENSG00000197111	PCBP2	100	100.000	ENSCANG00000004436	PCBP2	100	100.000	Colobus_angolensis_palliatus
ENSG00000197111	PCBP2	100	93.750	ENSCANG00000027678	-	100	87.736	Colobus_angolensis_palliatus
ENSG00000197111	PCBP2	98	87.302	ENSCGRG00001005050	-	99	77.910	Cricetulus_griseus_chok1gshd
ENSG00000197111	PCBP2	100	93.671	ENSCGRG00001000897	-	98	85.337	Cricetulus_griseus_chok1gshd
ENSG00000197111	PCBP2	100	100.000	ENSCGRG00001012894	Pcbp2	100	100.000	Cricetulus_griseus_chok1gshd
ENSG00000197111	PCBP2	100	94.444	ENSCGRG00001019293	-	100	76.438	Cricetulus_griseus_chok1gshd
ENSG00000197111	PCBP2	96	90.395	ENSCGRG00001023034	-	100	82.271	Cricetulus_griseus_chok1gshd
ENSG00000197111	PCBP2	100	100.000	ENSCGRG00000017884	-	100	99.724	Cricetulus_griseus_crigri
ENSG00000197111	PCBP2	100	93.671	ENSCGRG00000004207	-	98	85.337	Cricetulus_griseus_crigri
ENSG00000197111	PCBP2	100	94.444	ENSCGRG00000018025	-	100	76.164	Cricetulus_griseus_crigri
ENSG00000197111	PCBP2	100	84.375	ENSCSEG00000021490	pcbp2	100	80.000	Cynoglossus_semilaevis
ENSG00000197111	PCBP2	100	98.438	ENSCSEG00000010540	PCBP2	100	85.933	Cynoglossus_semilaevis
ENSG00000197111	PCBP2	100	93.750	ENSCVAG00000015775	pcbp2	100	88.994	Cyprinodon_variegatus
ENSG00000197111	PCBP2	100	96.875	ENSCVAG00000009913	PCBP2	100	89.308	Cyprinodon_variegatus
ENSG00000197111	PCBP2	100	98.438	ENSDARG00000099039	pcbp2	100	90.879	Danio_rerio
ENSG00000197111	PCBP2	100	98.413	ENSDNOG00000035361	-	86	98.413	Dasypus_novemcinctus
ENSG00000197111	PCBP2	94	76.667	ENSDNOG00000038064	-	86	83.824	Dasypus_novemcinctus
ENSG00000197111	PCBP2	89	75.000	ENSDNOG00000044136	-	95	52.805	Dasypus_novemcinctus
ENSG00000197111	PCBP2	100	100.000	ENSDNOG00000032621	-	100	99.686	Dasypus_novemcinctus
ENSG00000197111	PCBP2	98	74.603	ENSDNOG00000045706	-	99	69.375	Dasypus_novemcinctus
ENSG00000197111	PCBP2	99	90.506	ENSDNOG00000048307	-	100	90.506	Dasypus_novemcinctus
ENSG00000197111	PCBP2	99	71.154	ENSDNOG00000047920	-	99	58.663	Dasypus_novemcinctus
ENSG00000197111	PCBP2	100	69.444	ENSDNOG00000034227	-	100	60.839	Dasypus_novemcinctus
ENSG00000197111	PCBP2	100	69.444	ENSDNOG00000044742	-	95	66.421	Dasypus_novemcinctus
ENSG00000197111	PCBP2	99	93.631	ENSDORG00000025809	-	99	86.854	Dipodomys_ordii
ENSG00000197111	PCBP2	100	87.500	ENSDORG00000029549	-	100	80.818	Dipodomys_ordii
ENSG00000197111	PCBP2	100	100.000	ENSDORG00000001384	-	100	100.000	Dipodomys_ordii
ENSG00000197111	PCBP2	100	100.000	ENSETEG00000014741	PCBP2	100	98.066	Echinops_telfairi
ENSG00000197111	PCBP2	100	100.000	ENSEASG00005010021	PCBP2	100	100.000	Equus_asinus_asinus
ENSG00000197111	PCBP2	94	73.333	ENSEASG00005000781	-	80	76.543	Equus_asinus_asinus
ENSG00000197111	PCBP2	100	95.570	ENSECAG00000022389	-	100	96.785	Equus_caballus
ENSG00000197111	PCBP2	94	73.333	ENSECAG00000017851	-	78	76.829	Equus_caballus
ENSG00000197111	PCBP2	100	99.367	ENSEEUG00000001077	PCBP2	100	82.787	Erinaceus_europaeus
ENSG00000197111	PCBP2	100	98.438	ENSELUG00000010754	PCBP2	100	87.156	Esox_lucius
ENSG00000197111	PCBP2	100	98.438	ENSELUG00000014427	pcbp2	100	88.889	Esox_lucius
ENSG00000197111	PCBP2	100	100.000	ENSFCAG00000023348	PCBP2	100	100.000	Felis_catus
ENSG00000197111	PCBP2	100	100.000	ENSFALG00000002980	PCBP2	100	97.143	Ficedula_albicollis
ENSG00000197111	PCBP2	100	100.000	ENSFDAG00000017467	-	100	77.950	Fukomys_damarensis
ENSG00000197111	PCBP2	100	89.062	ENSFDAG00000021521	-	88	88.667	Fukomys_damarensis
ENSG00000197111	PCBP2	100	100.000	ENSFDAG00000003404	PCBP2	100	100.000	Fukomys_damarensis
ENSG00000197111	PCBP2	100	93.750	ENSFHEG00000009608	pcbp2	100	87.654	Fundulus_heteroclitus
ENSG00000197111	PCBP2	100	95.000	ENSFHEG00000016024	PCBP2	82	95.000	Fundulus_heteroclitus
ENSG00000197111	PCBP2	100	96.875	ENSGMOG00000009787	pcbp2	100	89.937	Gadus_morhua
ENSG00000197111	PCBP2	100	96.875	ENSGMOG00000001342	PCBP2	95	85.321	Gadus_morhua
ENSG00000197111	PCBP2	100	100.000	ENSGALG00000041030	PCBP2	100	99.396	Gallus_gallus
ENSG00000197111	PCBP2	100	93.750	ENSGAFG00000007972	pcbp2	100	89.308	Gambusia_affinis
ENSG00000197111	PCBP2	100	98.438	ENSGAFG00000013273	PCBP2	93	94.937	Gambusia_affinis
ENSG00000197111	PCBP2	100	93.750	ENSGACG00000003197	pcbp2	100	87.736	Gasterosteus_aculeatus
ENSG00000197111	PCBP2	100	98.438	ENSGACG00000006681	PCBP2	100	86.810	Gasterosteus_aculeatus
ENSG00000197111	PCBP2	100	100.000	ENSGAGG00000010410	PCBP2	100	99.698	Gopherus_agassizii
ENSG00000197111	PCBP2	100	100.000	ENSGGOG00000012613	PCBP2	100	100.000	Gorilla_gorilla
ENSG00000197111	PCBP2	100	93.750	ENSHBUG00000008769	pcbp2	100	86.728	Haplochromis_burtoni
ENSG00000197111	PCBP2	100	98.438	ENSHBUG00000018512	PCBP2	93	94.937	Haplochromis_burtoni
ENSG00000197111	PCBP2	97	94.286	ENSHGLG00000006371	-	95	84.142	Heterocephalus_glaber_female
ENSG00000197111	PCBP2	99	91.720	ENSHGLG00000017847	-	97	89.590	Heterocephalus_glaber_female
ENSG00000197111	PCBP2	100	96.409	ENSHGLG00000019854	-	100	96.409	Heterocephalus_glaber_female
ENSG00000197111	PCBP2	100	100.000	ENSHGLG00000001776	PCBP2	100	100.000	Heterocephalus_glaber_female
ENSG00000197111	PCBP2	99	91.083	ENSHGLG00100013811	-	100	83.281	Heterocephalus_glaber_male
ENSG00000197111	PCBP2	92	93.077	ENSHGLG00100012826	-	90	91.034	Heterocephalus_glaber_male
ENSG00000197111	PCBP2	100	100.000	ENSHGLG00100009675	PCBP2	100	100.000	Heterocephalus_glaber_male
ENSG00000197111	PCBP2	100	96.409	ENSHGLG00100020807	-	100	96.409	Heterocephalus_glaber_male
ENSG00000197111	PCBP2	97	94.286	ENSHGLG00100000389	-	95	77.937	Heterocephalus_glaber_male
ENSG00000197111	PCBP2	100	98.438	ENSHCOG00000020951	PCBP2	100	88.365	Hippocampus_comes
ENSG00000197111	PCBP2	100	88.889	ENSHCOG00000019886	pcbp2	100	82.075	Hippocampus_comes
ENSG00000197111	PCBP2	100	96.875	ENSIPUG00000024819	pcbp2	100	88.679	Ictalurus_punctatus
ENSG00000197111	PCBP2	100	88.889	ENSSTOG00000033478	-	100	76.276	Ictidomys_tridecemlineatus
ENSG00000197111	PCBP2	100	100.000	ENSSTOG00000003635	PCBP2	100	100.000	Ictidomys_tridecemlineatus
ENSG00000197111	PCBP2	98	79.558	ENSSTOG00000024304	-	99	76.836	Ictidomys_tridecemlineatus
ENSG00000197111	PCBP2	100	97.222	ENSJJAG00000019375	-	100	91.667	Jaculus_jaculus
ENSG00000197111	PCBP2	99	81.122	ENSJJAG00000019148	-	100	74.033	Jaculus_jaculus
ENSG00000197111	PCBP2	100	95.570	ENSJJAG00000019739	-	100	97.122	Jaculus_jaculus
ENSG00000197111	PCBP2	100	92.188	ENSKMAG00000011367	-	100	87.037	Kryptolebias_marmoratus
ENSG00000197111	PCBP2	100	98.438	ENSKMAG00000012031	PCBP2	97	90.506	Kryptolebias_marmoratus
ENSG00000197111	PCBP2	100	93.750	ENSLBEG00000010080	pcbp2	100	86.728	Labrus_bergylta
ENSG00000197111	PCBP2	100	98.438	ENSLBEG00000015211	PCBP2	93	95.000	Labrus_bergylta
ENSG00000197111	PCBP2	100	97.222	ENSLACG00000001442	PCBP2	97	95.570	Latimeria_chalumnae
ENSG00000197111	PCBP2	100	98.438	ENSLOCG00000005598	pcbp2	70	92.787	Lepisosteus_oculatus
ENSG00000197111	PCBP2	100	100.000	ENSLAFG00000013187	-	100	88.736	Loxodonta_africana
ENSG00000197111	PCBP2	100	100.000	ENSLAFG00000025534	-	100	94.199	Loxodonta_africana
ENSG00000197111	PCBP2	100	100.000	ENSMFAG00000003437	-	100	74.792	Macaca_fascicularis
ENSG00000197111	PCBP2	100	100.000	ENSMFAG00000044356	PCBP2	100	100.000	Macaca_fascicularis
ENSG00000197111	PCBP2	100	97.222	ENSMFAG00000042984	-	100	91.900	Macaca_fascicularis
ENSG00000197111	PCBP2	100	97.222	ENSMMUG00000048920	-	100	79.560	Macaca_mulatta
ENSG00000197111	PCBP2	100	100.000	ENSMMUG00000006608	-	100	100.000	Macaca_mulatta
ENSG00000197111	PCBP2	100	97.222	ENSMMUG00000016086	-	93	96.835	Macaca_mulatta
ENSG00000197111	PCBP2	100	100.000	ENSMNEG00000006864	-	100	77.285	Macaca_nemestrina
ENSG00000197111	PCBP2	99	94.983	ENSMNEG00000033408	-	96	95.318	Macaca_nemestrina
ENSG00000197111	PCBP2	100	100.000	ENSMNEG00000031958	PCBP2	100	100.000	Macaca_nemestrina
ENSG00000197111	PCBP2	100	100.000	ENSMLEG00000030333	-	100	75.069	Mandrillus_leucophaeus
ENSG00000197111	PCBP2	100	100.000	ENSMLEG00000033368	-	100	100.000	Mandrillus_leucophaeus
ENSG00000197111	PCBP2	100	98.438	ENSMAMG00000010416	PCBP2	93	95.570	Mastacembelus_armatus
ENSG00000197111	PCBP2	100	93.750	ENSMAMG00000024156	pcbp2	100	88.679	Mastacembelus_armatus
ENSG00000197111	PCBP2	100	98.438	ENSMZEG00005006692	PCBP2	93	94.937	Maylandia_zebra
ENSG00000197111	PCBP2	100	93.750	ENSMZEG00005026186	pcbp2	100	88.365	Maylandia_zebra
ENSG00000197111	PCBP2	89	95.775	ENSMGAG00000003191	PCBP2	99	96.089	Meleagris_gallopavo
ENSG00000197111	PCBP2	97	91.429	ENSMAUG00000018893	-	97	91.429	Mesocricetus_auratus
ENSG00000197111	PCBP2	100	80.189	ENSMAUG00000007839	Pcbp2	100	80.189	Mesocricetus_auratus
ENSG00000197111	PCBP2	100	100.000	ENSMICG00000027264	-	100	95.963	Microcebus_murinus
ENSG00000197111	PCBP2	100	100.000	ENSMICG00000011651	PCBP2	100	100.000	Microcebus_murinus
ENSG00000197111	PCBP2	100	96.875	ENSMICG00000029452	-	100	81.791	Microcebus_murinus
ENSG00000197111	PCBP2	100	100.000	ENSMOCG00000010409	Pcbp2	100	96.409	Microtus_ochrogaster
ENSG00000197111	PCBP2	100	89.431	ENSMOCG00000000686	-	100	89.431	Microtus_ochrogaster
ENSG00000197111	PCBP2	100	89.062	ENSMOCG00000016813	-	100	68.595	Microtus_ochrogaster
ENSG00000197111	PCBP2	99	77.576	ENSMOCG00000013934	-	94	78.528	Microtus_ochrogaster
ENSG00000197111	PCBP2	100	88.125	ENSMMOG00000010385	PCBP2	93	88.125	Mola_mola
ENSG00000197111	PCBP2	100	93.750	ENSMMOG00000011746	pcbp2	97	90.506	Mola_mola
ENSG00000197111	PCBP2	100	95.342	ENSMODG00000017748	-	100	95.342	Monodelphis_domestica
ENSG00000197111	PCBP2	100	100.000	ENSMODG00000000280	-	100	100.000	Monodelphis_domestica
ENSG00000197111	PCBP2	75	84.768	ENSMODG00000016543	-	100	93.377	Monodelphis_domestica
ENSG00000197111	PCBP2	100	85.938	ENSMODG00000020653	-	100	82.698	Monodelphis_domestica
ENSG00000197111	PCBP2	100	98.438	ENSMALG00000009673	PCBP2	100	87.156	Monopterus_albus
ENSG00000197111	PCBP2	100	92.188	ENSMALG00000022422	pcbp2	100	90.228	Monopterus_albus
ENSG00000197111	PCBP2	100	100.000	MGP_CAROLIEiJ_G0020353	Pcbp2	100	100.000	Mus_caroli
ENSG00000197111	PCBP2	100	100.000	ENSMUSG00000056851	Pcbp2	100	100.000	Mus_musculus
ENSG00000197111	PCBP2	100	100.000	MGP_SPRETEiJ_G0021246	Pcbp2	100	100.000	Mus_spretus
ENSG00000197111	PCBP2	100	100.000	ENSMPUG00000005980	PCBP2	100	100.000	Mustela_putorius_furo
ENSG00000197111	PCBP2	100	100.000	ENSMLUG00000009971	PCBP2	100	100.000	Myotis_lucifugus
ENSG00000197111	PCBP2	100	100.000	ENSNGAG00000018457	-	100	95.821	Nannospalax_galili
ENSG00000197111	PCBP2	100	100.000	ENSNGAG00000012054	Pcbp2	100	100.000	Nannospalax_galili
ENSG00000197111	PCBP2	100	98.438	ENSNBRG00000003872	PCBP2	93	95.000	Neolamprologus_brichardi
ENSG00000197111	PCBP2	100	93.750	ENSNBRG00000023314	pcbp2	100	86.728	Neolamprologus_brichardi
ENSG00000197111	PCBP2	100	100.000	ENSNLEG00000017693	PCBP2	100	100.000	Nomascus_leucogenys
ENSG00000197111	PCBP2	100	100.000	ENSMEUG00000001887	PCBP2	100	95.902	Notamacropus_eugenii
ENSG00000197111	PCBP2	100	100.000	ENSOPRG00000004680	PCBP2	81	100.000	Ochotona_princeps
ENSG00000197111	PCBP2	100	91.772	ENSODEG00000013422	-	100	83.934	Octodon_degus
ENSG00000197111	PCBP2	100	94.444	ENSODEG00000003534	-	100	83.648	Octodon_degus
ENSG00000197111	PCBP2	100	98.438	ENSODEG00000020292	-	94	89.779	Octodon_degus
ENSG00000197111	PCBP2	100	100.000	ENSODEG00000006995	-	100	96.986	Octodon_degus
ENSG00000197111	PCBP2	89	79.511	ENSODEG00000015604	-	100	79.511	Octodon_degus
ENSG00000197111	PCBP2	100	100.000	ENSODEG00000013186	PCBP2	100	100.000	Octodon_degus
ENSG00000197111	PCBP2	92	96.970	ENSODEG00000013052	-	100	86.908	Octodon_degus
ENSG00000197111	PCBP2	100	93.750	ENSONIG00000017003	pcbp2	100	88.365	Oreochromis_niloticus
ENSG00000197111	PCBP2	100	98.438	ENSONIG00000005135	PCBP2	100	87.156	Oreochromis_niloticus
ENSG00000197111	PCBP2	65	80.672	ENSOCUG00000025545	-	90	81.967	Oryctolagus_cuniculus
ENSG00000197111	PCBP2	99	79.487	ENSOCUG00000021452	-	99	75.000	Oryctolagus_cuniculus
ENSG00000197111	PCBP2	100	67.485	ENSOCUG00000021790	-	100	59.568	Oryctolagus_cuniculus
ENSG00000197111	PCBP2	100	100.000	ENSOCUG00000022490	-	99	91.436	Oryctolagus_cuniculus
ENSG00000197111	PCBP2	100	80.556	ENSOCUG00000020940	-	96	61.145	Oryctolagus_cuniculus
ENSG00000197111	PCBP2	100	72.973	ENSOCUG00000025394	-	99	65.902	Oryctolagus_cuniculus
ENSG00000197111	PCBP2	100	98.438	ENSORLG00000005176	PCBP2	100	89.623	Oryzias_latipes
ENSG00000197111	PCBP2	100	93.750	ENSORLG00000012872	pcbp2	100	86.728	Oryzias_latipes
ENSG00000197111	PCBP2	100	93.750	ENSORLG00020016290	pcbp2	100	88.365	Oryzias_latipes_hni
ENSG00000197111	PCBP2	100	98.438	ENSORLG00020017901	PCBP2	100	89.623	Oryzias_latipes_hni
ENSG00000197111	PCBP2	100	93.750	ENSORLG00015010679	pcbp2	100	88.679	Oryzias_latipes_hsok
ENSG00000197111	PCBP2	100	98.438	ENSORLG00015013439	PCBP2	100	89.623	Oryzias_latipes_hsok
ENSG00000197111	PCBP2	100	93.750	ENSOMEG00000005759	pcbp2	100	86.728	Oryzias_melastigma
ENSG00000197111	PCBP2	100	98.438	ENSOMEG00000019014	PCBP2	100	89.623	Oryzias_melastigma
ENSG00000197111	PCBP2	100	100.000	ENSOARG00000016466	PCBP2	100	100.000	Ovis_aries
ENSG00000197111	PCBP2	100	92.767	ENSPPAG00000040128	-	100	92.767	Pan_paniscus
ENSG00000197111	PCBP2	100	97.521	ENSPPAG00000027632	PCBP2	100	97.521	Pan_paniscus
ENSG00000197111	PCBP2	100	100.000	ENSPPRG00000005414	PCBP2	100	100.000	Panthera_pardus
ENSG00000197111	PCBP2	100	100.000	ENSPTIG00000020757	PCBP2	100	99.727	Panthera_tigris_altaica
ENSG00000197111	PCBP2	87	98.958	ENSPTIG00000006712	-	96	98.958	Panthera_tigris_altaica
ENSG00000197111	PCBP2	100	100.000	ENSPTRG00000005018	PCBP2	100	100.000	Pan_troglodytes
ENSG00000197111	PCBP2	100	100.000	ENSPANG00000029560	PCBP2	100	100.000	Papio_anubis
ENSG00000197111	PCBP2	100	100.000	ENSPANG00000034640	-	100	75.623	Papio_anubis
ENSG00000197111	PCBP2	100	96.875	ENSPANG00000022646	-	100	89.426	Papio_anubis
ENSG00000197111	PCBP2	100	96.875	ENSPKIG00000002205	PCBP2	100	82.736	Paramormyrops_kingsleyae
ENSG00000197111	PCBP2	100	97.222	ENSPKIG00000006570	PCBP2	100	90.881	Paramormyrops_kingsleyae
ENSG00000197111	PCBP2	100	100.000	ENSPSIG00000007484	PCBP2	100	94.017	Pelodiscus_sinensis
ENSG00000197111	PCBP2	100	91.875	ENSPMGG00000003416	PCBP2	93	91.875	Periophthalmus_magnuspinnatus
ENSG00000197111	PCBP2	100	92.188	ENSPMGG00000004381	pcbp2	100	88.179	Periophthalmus_magnuspinnatus
ENSG00000197111	PCBP2	100	100.000	ENSPEMG00000013236	Pcbp2	100	100.000	Peromyscus_maniculatus_bairdii
ENSG00000197111	PCBP2	96	98.058	ENSPEMG00000002413	-	100	98.058	Peromyscus_maniculatus_bairdii
ENSG00000197111	PCBP2	100	94.444	ENSPCIG00000013794	-	96	82.353	Phascolarctos_cinereus
ENSG00000197111	PCBP2	100	88.889	ENSPCIG00000030555	-	99	55.385	Phascolarctos_cinereus
ENSG00000197111	PCBP2	100	100.000	ENSPCIG00000006658	-	100	100.000	Phascolarctos_cinereus
ENSG00000197111	PCBP2	95	78.667	ENSPCIG00000013664	-	92	74.841	Phascolarctos_cinereus
ENSG00000197111	PCBP2	100	93.750	ENSPFOG00000010086	pcbp2	100	89.308	Poecilia_formosa
ENSG00000197111	PCBP2	100	98.438	ENSPFOG00000008011	PCBP2	100	89.937	Poecilia_formosa
ENSG00000197111	PCBP2	100	98.438	ENSPLAG00000017518	PCBP2	100	89.937	Poecilia_latipinna
ENSG00000197111	PCBP2	100	93.750	ENSPLAG00000003153	pcbp2	100	89.308	Poecilia_latipinna
ENSG00000197111	PCBP2	100	93.750	ENSPMEG00000021528	pcbp2	100	89.308	Poecilia_mexicana
ENSG00000197111	PCBP2	100	98.438	ENSPMEG00000007633	PCBP2	93	94.937	Poecilia_mexicana
ENSG00000197111	PCBP2	100	98.438	ENSPREG00000007742	PCBP2	100	87.462	Poecilia_reticulata
ENSG00000197111	PCBP2	100	93.750	ENSPREG00000006202	pcbp2	100	87.654	Poecilia_reticulata
ENSG00000197111	PCBP2	100	100.000	ENSPPYG00000004581	PCBP2	100	100.000	Pongo_abelii
ENSG00000197111	PCBP2	92	100.000	ENSPCAG00000005154	PCBP2	100	92.898	Procavia_capensis
ENSG00000197111	PCBP2	100	100.000	ENSPCOG00000025737	PCBP2	100	100.000	Propithecus_coquereli
ENSG00000197111	PCBP2	100	100.000	ENSPVAG00000012284	PCBP2	100	99.727	Pteropus_vampyrus
ENSG00000197111	PCBP2	100	98.438	ENSPNYG00000014206	PCBP2	93	94.937	Pundamilia_nyererei
ENSG00000197111	PCBP2	100	93.750	ENSPNYG00000018792	pcbp2	100	88.365	Pundamilia_nyererei
ENSG00000197111	PCBP2	100	98.438	ENSPNAG00000001885	pcbp2	100	89.308	Pygocentrus_nattereri
ENSG00000197111	PCBP2	100	95.312	ENSPNAG00000009446	-	99	84.227	Pygocentrus_nattereri
ENSG00000197111	PCBP2	97	91.429	ENSRNOG00000006713	AC099137.1	100	78.485	Rattus_norvegicus
ENSG00000197111	PCBP2	100	100.000	ENSRNOG00000036852	Pcbp2	100	100.000	Rattus_norvegicus
ENSG00000197111	PCBP2	100	100.000	ENSRBIG00000039085	PCBP2	100	100.000	Rhinopithecus_bieti
ENSG00000197111	PCBP2	100	97.222	ENSRBIG00000033468	-	100	85.220	Rhinopithecus_bieti
ENSG00000197111	PCBP2	100	97.222	ENSRROG00000033285	-	100	85.220	Rhinopithecus_roxellana
ENSG00000197111	PCBP2	100	100.000	ENSRROG00000041377	PCBP2	100	100.000	Rhinopithecus_roxellana
ENSG00000197111	PCBP2	100	100.000	ENSSBOG00000020308	PCBP2	100	100.000	Saimiri_boliviensis_boliviensis
ENSG00000197111	PCBP2	100	100.000	ENSSHAG00000007342	PCBP2	100	100.000	Sarcophilus_harrisii
ENSG00000197111	PCBP2	100	97.222	ENSSFOG00015017796	PCBP2	100	90.881	Scleropages_formosus
ENSG00000197111	PCBP2	100	98.438	ENSSFOG00015013231	PCBP2	100	88.000	Scleropages_formosus
ENSG00000197111	PCBP2	100	93.750	ENSSMAG00000005182	pcbp2	100	87.037	Scophthalmus_maximus
ENSG00000197111	PCBP2	100	98.438	ENSSMAG00000012889	PCBP2	100	86.850	Scophthalmus_maximus
ENSG00000197111	PCBP2	100	93.750	ENSSDUG00000021325	pcbp2	100	87.037	Seriola_dumerili
ENSG00000197111	PCBP2	100	98.438	ENSSDUG00000018636	PCBP2	93	94.937	Seriola_dumerili
ENSG00000197111	PCBP2	100	93.750	ENSSLDG00000008839	pcbp2	100	87.037	Seriola_lalandi_dorsalis
ENSG00000197111	PCBP2	100	98.438	ENSSLDG00000002018	PCBP2	100	89.623	Seriola_lalandi_dorsalis
ENSG00000197111	PCBP2	98	100.000	ENSSARG00000000999	PCBP2	84	100.000	Sorex_araneus
ENSG00000197111	PCBP2	100	100.000	ENSSPUG00000006081	PCBP2	100	98.187	Sphenodon_punctatus
ENSG00000197111	PCBP2	100	98.438	ENSSPAG00000022833	PCBP2	100	87.156	Stegastes_partitus
ENSG00000197111	PCBP2	100	93.750	ENSSPAG00000017005	pcbp2	100	88.679	Stegastes_partitus
ENSG00000197111	PCBP2	100	100.000	ENSSSCG00000000274	PCBP2	100	100.000	Sus_scrofa
ENSG00000197111	PCBP2	100	86.076	ENSSSCG00000033742	-	100	85.629	Sus_scrofa
ENSG00000197111	PCBP2	100	100.000	ENSTGUG00000016232	PCBP2	99	74.919	Taeniopygia_guttata
ENSG00000197111	PCBP2	100	96.875	ENSTRUG00000011419	PCBP2	99	85.321	Takifugu_rubripes
ENSG00000197111	PCBP2	100	93.750	ENSTRUG00000009361	pcbp2	100	88.994	Takifugu_rubripes
ENSG00000197111	PCBP2	100	93.750	ENSTNIG00000012585	pcbp2	100	88.679	Tetraodon_nigroviridis
ENSG00000197111	PCBP2	99	89.796	ENSTBEG00000015592	PCBP2	100	86.464	Tupaia_belangeri
ENSG00000197111	PCBP2	100	100.000	ENSTTRG00000017174	PCBP2	100	84.426	Tursiops_truncatus
ENSG00000197111	PCBP2	100	100.000	ENSUAMG00000023889	PCBP2	100	100.000	Ursus_americanus
ENSG00000197111	PCBP2	100	100.000	ENSUMAG00000010437	PCBP2	100	100.000	Ursus_maritimus
ENSG00000197111	PCBP2	100	100.000	ENSVPAG00000000406	PCBP2	100	97.738	Vicugna_pacos
ENSG00000197111	PCBP2	100	100.000	ENSVVUG00000028129	PCBP2	100	100.000	Vulpes_vulpes
ENSG00000197111	PCBP2	100	100.000	ENSXETG00000012658	pcbp3	100	87.535	Xenopus_tropicalis
ENSG00000197111	PCBP2	100	95.000	ENSXCOG00000013797	PCBP2	93	95.000	Xiphophorus_couchianus
ENSG00000197111	PCBP2	80	100.000	ENSXCOG00000012907	pcbp2	100	85.085	Xiphophorus_couchianus
ENSG00000197111	PCBP2	100	93.750	ENSXMAG00000021752	pcbp2	100	89.308	Xiphophorus_maculatus
ENSG00000197111	PCBP2	100	98.438	ENSXMAG00000023803	PCBP2	100	89.937	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000398	mRNA splicing, via spliceosome	-	TAS	Process
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0003723	RNA binding	7607214.	IDA	Function
GO:0005515	protein binding	16713569.17183366.19881509.22720776.25416956.	IPI	Function
GO:0005634	nucleus	22720776.	IDA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005737	cytoplasm	19029303.	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0005925	focal adhesion	21423176.	HDA	Component
GO:0016020	membrane	19946888.	HDA	Component
GO:0016070	RNA metabolic process	-	TAS	Process
GO:0016071	mRNA metabolic process	7556077.	NAS	Process
GO:0019899	enzyme binding	19881509.	IPI	Function
GO:0031625	ubiquitin protein ligase binding	19881509.	IPI	Function
GO:0032480	negative regulation of type I interferon production	-	TAS	Process
GO:0039694	viral RNA genome replication	12414943.	IDA	Process
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	19881509.	IMP	Process
GO:0045087	innate immune response	-	IEA	Process
GO:0050687	negative regulation of defense response to virus	19881509.	IMP	Process
GO:0051607	defense response to virus	-	IEA	Process
GO:0070062	extracellular exosome	23533145.	HDA	Component
GO:0075522	IRES-dependent viral translational initiation	12414943.	IDA	Process
GO:1990829	C-rich single-stranded DNA binding	-	IEA	Function

EuRBPDB

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

RBPome

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Expression

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Pathways

PPI

Paralogs

Orthologs

Gene Ontology

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Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.