EuRBPDB

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TCGA tumor abbreviations
  • ACCAdrenocortical carcinoma
  • BLCABladder Urothelial Carcinoma
  • BRCABreast invasive carcinoma
  • CESCCervical squamous cell carcinoma and endocervical adenocarcinoma
  • CHOLCholangio carcinoma
  • COADColon adenocarcinoma
  • DLBCLymphoid Neoplasm Diffuse Large B-cell Lymphoma
  • ESCAEsophageal carcinoma
  • GBMGlioblastoma multiforme
  • HNSCHead and Neck squamous cell carcinoma
  • KICHKidney Chromophobe
  • KIRCKidney renal clear cell carcinoma
  • KIRPKidney renal papillary cell carcinoma
  • LAMLAcute Myeloid Leukemia
  • LGGBrain Lower Grade Glioma
  • LIHCLiver hepatocellular carcinoma
  • LUADLung adenocarcinoma
  • LUSCLung squamous cell carcinoma
  • MESOMesothelioma
  • OVOvarian serous cystadenocarcinoma
  • PAADPancreatic adenocarcinoma
  • PCPGPheochromocytoma and Paraganglioma
  • PRADProstate adenocarcinoma
  • READRectum adenocarcinoma
  • SARCSarcoma
  • SKCMSkin Cutaneous Melanoma
  • STADStomach adenocarcinoma
  • TGCTThyroid carcinoma
  • THCAThyroid carcinoma
  • THYMThymoma
  • UCECUterine Corpus Endometrial Carcinoma
  • UCSUterine Carcinosarcoma
  • UVMUveal Melanoma

Note: Click here to get the extension of tumor abbreviations.


  • Cancer Related Information
  • Basic Information

Cancer associated literatures
PIDTitleArticle TimeAuthorDoi
23391111The genetics of neuroendocrine tumors.Semin Oncol2013 Febberg Kdoi: 10.1053/j.seminoncol.2012.11.005.
28591701DAXX/ATRX and MEN1 genes are strong prognostic markers in pancreatic neuroendocrine tumors.Oncotarget2017 Jul 25Park JKdoi: 10.18632/oncotarget.17964.
23954140Clinicopathologic significance of immunostaining of α-thalassemia/mental retardation syndrome X-linked protein and death domain-associated protein in neuroendocrine tumors.Hum Pathol2013 OctChen SFdoi: 10.1016/j.humpath.2013.04.025
23539629Death domain-associated protein DAXX promotes ovarian cancer development and chemoresistance.J Biol Chem2013 May 10Pan WWdoi: 10.1074/jbc.M112.446369
25748050Silencing Daxx increases the anti-tumor activity of a TRAIL/shRNA Bcl-xL-expressing oncolytic adenovirus through enhanced viral replication and cellular arrest.Cell Signal2015 JunKang Sdoi: 10.1016/j.cellsig.2015.02.028
25903140Transcriptional Repressor DAXX Promotes Prostate Cancer Tumorigenicity via Suppression of Autophagy.J Biol Chem2015 Jun 19Puto LAdoi: 10.1074/jbc.M115.658765
17938171A suppressive role of the prolyl isomerase Pin1 in cellular apoptosis mediated by the death-associated protein Daxx.J Biol Chem2007 Dec 14Ryo A-
22614022Cross-talk between phosphorylation and SUMOylation regulates transforming activities of an adenoviral oncoprotein.Oncogene2013 Mar 28Wimmer Pdoi: 10.1038/onc.2012.187
27872097Menin and Daxx Interact to Suppress Neuroendocrine Tumors through Epigenetic Control of the Membrane Metallo-Endopeptidase.Cancer Res2017 Jan 15Feng Zdoi: 10.1158/0008-5472.CAN-16-1567
29599123Tumor suppressor functions of DAXX through histone H3.3/H3K9me3 pathway in pancreatic NETs.Endocr Relat Cancer2018 JunUeda Hdoi: 10.1530/ERC-17-0328
23239745Daxx regulates mitotic progression and prostate cancer predisposition.Carcinogenesis2013 AprKwan PSdoi: 10.1093/carcin/bgs391
23642739Overexpression of the chromatin remodeler death-domain-associated protein in prostate cancer is an independent predictor of early prostate-specific antigen recurrence.Hum Pathol2013 SepTsourlakis MCdoi: 10.1016/j.humpath.2013.01.022
23295648Berberine represses DAXX gene transcription and induces cancer cell apoptosis.Lab Invest2013 MarLi Jdoi: 10.1038/labinvest.2012.172
24398161Distribution and location of Daxx in cervical epithelial cells with high risk human papillomavirus positive.Diagn Pathol2014 Jan 8Tang SYdoi: 10.1186/1746-1596-9-1.
28062559ATRX and DAXX: Mechanisms and Mutations.Cold Spring Harb Perspect Med2017 Mar 1Dyer MAdoi: 10.1101/cshperspect.a026567.
27578458Switch telomerase to ALT mechanism by inducing telomeric DNA damages and dysfunction of ATRX and DAXX.Sci Rep2016 Aug 31Hu Ydoi: 10.1038/srep32280.

Expression in 33 cancers

Mutations
CancerChrPosition Mutation TypedbSNPProtein-change Allele FreqRBD
ACCchr633320847Nonsense_MutationnovelQ310*0.81
ACCchr633321057Frame_Shift_DelnovelC240*0.29
ACCchr633320451Frame_Shift_DelNAR394Sfs*220.9
ACCchr633320546Missense_MutationnovelR362P0.71
BLCAchr633321740Missense_MutationnovelE62D0.21
BLCAchr633320809SilentnovelI322I0.22
BLCAchr633321293Missense_MutationnovelP161R0.27
BLCAchr633320965SilentNAR270R0.41
BLCAchr633319658SilentnovelE554E0.34
BLCAchr633319058Missense_MutationnovelP701L0.37
BLCAchr633319423Missense_Mutationrs773398360R633W0.17
BLCAchr633321466SilentNAA103A0.03
BLCAchr633320818Missense_MutationnovelD319E0.09
BLCAchr633319557Missense_MutationNAS588F0.08
BLCAchr633319012SilentnovelR716R0.14
BLCAchr633319160Missense_MutationnovelP667L0.23
BLCAchr633321511SilentNAL88L0.16
BRCAchr633320589Missense_Mutationrs758422357V348I0.28
BRCAchr633320489Missense_MutationNAM381R0.16
BRCAchr633320800In_Frame_DelnovelL324_Q325del0.21
BRCAchr633321348Missense_MutationnovelL143M0.1
BRCAchr633321678Intronnovel0.34
BRCAchr633318781Missense_MutationNAD729N0.26
BRCAchr633321448SilentnovelL109L0.17
CESCchr633320536SilentNAR365R0.26
CESCchr633319743Missense_Mutationrs141395832R526H0.49
CESCchr633321139SilentnovelL212L0.41
CESCchr6333186263'UTRnovel0.18
CESCchr633319055Missense_Mutationrs763046918S702F0.31
CESCchr633321261Missense_MutationnovelE172K0.45
CHOLchr633321900Missense_MutationnovelV9E0.56
COADchr633319435Frame_Shift_InsNAC629Lfs*290.36
COADchr633320421Missense_MutationnovelH404Y0.36
COADchr633319737Missense_MutationnovelV528G0.11
COADchr633321917SilentNAT3T0.35
COADchr633318782SilentnovelC728C0.56
COADchr633321677Intronnovel0.54
COADchr633319436Frame_Shift_DelNAC629Afs*160.36
COADchr633321918Missense_MutationNAT3I0.22
COADchr633321854SilentnovelP24P0.45
COADchr633321724Missense_MutationNAE68K0.63
COADchr633321884Silentrs767653980D14D0.26
COADchr633321791SilentNAH45H0.28
COADchr633318756Nonsense_MutationNAS737*0.23
COADchr633320248Intronnovel0.25
COADchr633319144SilentNAP672P0.36
COADchr633321207Missense_MutationnovelR190C0.49
ESCAchr633319191Missense_MutationnovelE657Q0.09
ESCAchr633321757Missense_MutationnovelK57E0.58
GBMchr633320835Nonsense_MutationnovelQ314*0.5
GBMchr633319169Missense_MutationNAC664F0.11
GBMchr633319186Missense_MutationnovelK658N0.25
GBMchr633320352Intronnovel0.28
GBMchr633319381Missense_MutationnovelS647C0.63
GBMchr633319762Missense_MutationnovelE520K0.06
GBMchr6333228745'UTRnovel0.12
GBMchr633320894Missense_MutationnovelE294V0.1
GBMchr633319561Missense_MutationNAS587P0.45
HNSCchr633319148Missense_MutationnovelS671F0.06
HNSCchr633321028Silentrs140033328T249T0.34
HNSCchr633319529SilentnovelF597F0.36
HNSCchr633319174Missense_MutationnovelK662N0.26
HNSCchr633319787SilentnovelG511G0.07
HNSCchr633320965SilentNAR270R0.3
KIRCchr633321727Missense_MutationNAF67I0.16
KIRCchr633320387Missense_Mutationrs775804750S415F0.05
KIRCchr633320106Missense_MutationNAE457V0.18
KIRCchr633321075Missense_Mutationrs767991311R234C0.21
KIRCchr633319115Missense_Mutationrs377663648S682C0.26
KIRPchr633320044Frame_Shift_InsnovelE478*0.43
KIRPchr633321526SilentnovelE83E0.21
LAMLchr633321284Missense_MutationnovelL164P0.11
LAMLchr633321023Missense_Mutationrs200273259R251H0.03
LGGchr633320085Missense_MutationnovelE464V0.08
LGGchr633320829Missense_MutationnovelA316T0.41
LIHCchr633320457Missense_MutationnovelK392Q0.43
LIHCchr633321477Missense_MutationnovelL100V0.43
LIHCchr633320219Splice_SitenovelX418_splice0.14
LUADchr633321174Missense_MutationnovelE201K0.13
LUADchr633319820SilentNAL500L0.35
LUADchr633321406SilentnovelL123L0.16
LUADchr633319624Missense_MutationNAL566F0.3
LUADchr633320229Splice_Regionnovel0.07
LUADchr633321396Missense_MutationnovelI127V0.27
LUADchr633319557Missense_MutationNAS588Y0.24
LUADchr633321895Missense_Mutationrs780256009D11N0.23
LUADchr633321915Missense_MutationnovelA4V0.22
LUADchr6333229345'UTRnovel0.43
LUADchr6333229585'UTRnovel0.37
LUADchr633318758Silentrs755206233L736L0.21
LUSCchr633320842SilentnovelL311L0.04
LUSCchr633319719Nonsense_MutationnovelS534*0.14
LUSCchr633320426Missense_MutationnovelS402F0.16
LUSCchr633321446Missense_MutationnovelS110F0.11
LUSCchr6333229825'UTRnovel0.24
LUSCchr6333229715'UTRnovel0.5
LUSCchr633321026Missense_MutationNAG250D0.5
LUSCchr633320463Missense_Mutationrs573854582E390K0.14
LUSCchr633320506SilentnovelV375V0.22
LUSCchr633320779SilentnovelL332L0.22
LUSCchr633319695Missense_MutationnovelS542I0.51
LUSCchr633320047Missense_MutationnovelD477Y0.74
LUSCchr6333229665'UTRnovel0.26
LUSCchr633321470Missense_MutationNAS102L0.13
LUSCchr633319560Missense_Mutationrs760084261S587F0.29
LUSCchr633321248Missense_MutationnovelS176C0.32
LUSCchr633321483Missense_MutationnovelL98V0.24
LUSCchr633320201SilentnovelQ425Q0.33
LUSCchr633320340Intronnovel0.13
OVchr633321646Intronnovel0.06
OVchr633321285Missense_MutationnovelL164F0.1
OVchr633318772Nonsense_MutationnovelE732*0.03
OVchr6333186623'UTRnovel0.17
OVchr633319151Missense_MutationnovelP670H0.04
OVchr6333219665'UTRnovel0.11
OVchr633321091Frame_Shift_DelnovelK229Sfs*40.07
OVchr633320880Nonsense_MutationNAR299*0.39
PAADchr633319696Missense_MutationnovelS542G0.17
PAADchr633320886Missense_MutationnovelA297S0.21
PAADchr633321025SilentnovelG250G0.17
PAADchr633320938Frame_Shift_DelnovelP280Lfs*140.55
PRADchr633319676Frame_Shift_DelnovelN548Kfs*80.25
PRADchr633319501Missense_MutationNAM607V0.08
READchr633319836Missense_MutationnovelS495N0.32
READchr633321883Missense_Mutationrs758327720E15K0.22
READchr633319436Frame_Shift_DelNAC629Afs*160.14
READchr633320831Missense_MutationnovelD315V0.28
SARCchr6333186263'UTRnovel0.11
SKCMchr6333219385'UTRnovel0.24
SKCMchr633320214Missense_MutationNAG421E0.23
SKCMchr633319111SilentnovelS683S0.15
SKCMchr6333229405'UTRnovel0.45
SKCMchr6333229965'UTRnovel0.35
SKCMchr6333229965'UTRnovel0.73
SKCMchr633318750Missense_MutationnovelS739F0.19
SKCMchr6333229665'UTRnovel0.23
SKCMchr633321002Missense_MutationnovelP258L0.14
SKCMchr633321465Missense_MutationnovelE104K0.47
SKCMchr633321804Missense_MutationNAS41F0.33
SKCMchr6333229665'UTRnovel0.33
SKCMchr633319635Missense_MutationNAP562L0.52
SKCMchr6333229665'UTRnovel0.33
SKCMchr6333229755'UTRrs5499986120.41
SKCMchr633319423Missense_Mutationrs773398360R633W0.23
SKCMchr633320398Silentrs561840459A411A0.22
SKCMchr633321420Missense_Mutationrs773142629R119W0.32
SKCMchr633321273Missense_MutationnovelP168S0.33
SKCMchr633321274SilentnovelD167D0.33
SKCMchr633320411Missense_MutationNAD407V0.25
SKCMchr633320937Missense_MutationNAP280S0.3
SKCMchr633319141SilentNAL673L0.38
SKCMchr6333229655'UTRnovel0.61
SKCMchr633320421Missense_MutationnovelH404Y0.33
SKCMchr633320422SilentnovelS403S0.33
SKCMchr633321312Missense_MutationNAP155S0.4
SKCMchr633321785SilentnovelA47A0.17
SKCMchr633321786Missense_MutationnovelA47V0.17
SKCMchr633319586SilentNAT578T0.26
SKCMchr633320577SilentnovelL352L0.29
SKCMchr633320578SilentnovelA351A0.29
SKCMchr6333230045'UTRnovel0.4
SKCMchr6333230055'UTRnovel0.38
STADchr633320120SilentNAE452E0.23
STADchr633320440SilentNAR397R0.19
STADchr633321420Missense_Mutationrs773142629R119W0.07
STADchr633320823Nonsense_Mutationrs779014832R318*0.2
STADchr633321634Intronnovel0.08
STADchr633319741Missense_MutationNAI527V0.34
STADchr633319736SilentNAV528V0.31
STADchr633321745SilentNAL61L0.25
STADchr633319610Missense_MutationnovelE570D0.08
STADchr6333219385'UTRnovel0.34
STADchr633321491Missense_MutationNAA95V0.28
STADchr633319435Frame_Shift_InsNAC629Lfs*290.31
STADchr633321096Missense_MutationnovelR227W0.26
STADchr6333229885'UTRnovel0.33
STADchr6333229795'UTRnovel0.33
STADchr633321063Nonsense_MutationNAR238*0.29
STADchr633320062Missense_MutationNAE472K0.4
STADchr633319705Missense_MutationNAA539P0.26
STADchr633320987Missense_MutationNAR263H0.21
STADchr633319743Missense_Mutationrs141395832R526H0.22
UCECchr633320111Missense_MutationNAE455D0.16
UCECchr633320161Missense_MutationNAD439Y0.31
UCECchr633319471Missense_Mutationrs148540788V617I0.39
UCECchr633321027Missense_Mutationrs751767798G250S0.37
UCECchr633319820SilentNAL500L0.38
UCECchr633320508Missense_Mutationrs61737694V375I0.43
UCECchr633321252Missense_MutationnovelA175T0.48
UCECchr6333228765'UTRNA0.52
UCECchr633320589Missense_Mutationrs758422357V348I0.28
UCECchr633321227Missense_MutationnovelG183V0.45
UCECchr633321883Missense_Mutationrs758327720E15K0.42
UCECchr633319786Missense_MutationnovelK512E0.31
UCECchr633320374Splice_Regionnovel0.32
UCECchr633321627Intronnovel0.5
UCECchr633320345Intronnovel0.11
UCECchr633318781Missense_MutationNAD729N0.04
UCECchr633321489Missense_MutationNAH96Y0.29
UCECchr633320159Silentrs148860789D439D0.17
UCECchr633320463Missense_Mutationrs573854582E390K0.18
UCECchr633320158Missense_Mutationrs375012684D440N0.16
UCECchr633319181Missense_MutationnovelG660E0.26
UCECchr633319472SilentnovelG616G0.38
UCECchr633320966Missense_Mutationrs533137350R270H0.29
UCECchr633318781Missense_MutationNAD729N0.46
UCECchr633321725Silentrs781311994F67F0.33
UCECchr633318763Missense_MutationnovelV735M0.46
UCECchr633319486Missense_MutationnovelS612T0.51
UCECchr633321045Missense_MutationnovelD244Y0.46
UCECchr633321781Nonsense_MutationnovelG49*0.09
UCECchr633321611Intronnovel0.41
UCECchr633321220SilentnovelR185R0.14
UCECchr633320098Missense_MutationNAD460Y0.29
UCECchr633321172Missense_MutationNAE201D0.4
UCECchr633320375Splice_Regionnovel0.37
UCECchr633321763Missense_Mutationrs749662897G55S0.47
UCECchr633320401Missense_MutationnovelE410D0.56
UCECchr633320784Missense_MutationnovelD331N0.46
UCECchr633319383Missense_MutationnovelN646S0.37
UCECchr633321236Missense_MutationnovelR180M0.38
UCECchr633319667SilentnovelQ551Q0.25
UCECchr633318764Silentrs372800743I734I0.26
UCECchr633321530Missense_MutationnovelP82H0.45
UCECchr633319435Frame_Shift_InsNAC629Lfs*290.21
UCECchr633320820Missense_MutationNAD319N0.36
UCECchr633321758Missense_MutationNAK56N0.29
UCECchr633319429Missense_MutationnovelK631Q0.21
UCECchr633321406Silentrs142969892L123L0.24
UCECchr633321883Missense_Mutationrs758327720E15K0.4
UCECchr633320247Intronnovel0.34
UCECchr633321187Silentrs768909481A196A0.41
UCECchr633321164Missense_MutationnovelR204Q0.33
UCECchr633321329Missense_Mutationrs776829106A149V0.36

Copy Number Variations (CNVs)
CancerTypeFreq Q-value

Survival Analysis
CancerP-value Q-value
THYM0.021

Kaplan-Meier Survival Analysis

KIRC0.044

Kaplan-Meier Survival Analysis

MESO0.046

Kaplan-Meier Survival Analysis

ACC0.00093

Kaplan-Meier Survival Analysis

PRAD0.04

Kaplan-Meier Survival Analysis

BRCA0.00035

Kaplan-Meier Survival Analysis

KIRP0.0007

Kaplan-Meier Survival Analysis

COAD0.035

Kaplan-Meier Survival Analysis

READ0.03

Kaplan-Meier Survival Analysis

LAML0.0001

Kaplan-Meier Survival Analysis

LIHC0.0027

Kaplan-Meier Survival Analysis

UVM0.00011

Kaplan-Meier Survival Analysis

OV0.019

Kaplan-Meier Survival Analysis

Drugs

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Eesembl ID



Cell lines and drugs in GSE70138 or GSE92742

  • Description
  • RBPome
  • Literatures
  • Expression
  • Transcripts
  • Gene Model
  • Pathways
  • Phenotypes
  • PPI
  • Gene Ontology
Description
Ensembl ID
ENSG00000204209 (Gene tree)
Gene ID
1616
Gene Symbol
DAXX
Alias
DAP6
Full Name
death domain associated protein
Gene Type
protein_coding
Species
Homo_sapiens
Status
confidence
Strand
Minus strand
Length
4,459 bases
Position
chr6:33,318,558-33,323,016
Accession
2681
RBP type
non-canonical RBP
Summary
This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008]
RNA binding proteome (RBPome)
PIDTitleMethod TimeAuthorDoi
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & HEK2932019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & MCF10A2019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2

Literatures on RNA binding capacity
PIDTitleArticle TimeAuthorDoi
12526053Genetic characterization of new Dobrava hantavirus isolate from Greece.J Med Virol2003 MarNemirov K-
Expression
Transcripts
Transcript IDNameLengthRefSeq ID Protein IDLengthRefSeq IDUniportKB ID
ENST00000620164DAXX-2112462-ENSP00000482399688 (aa)-Q9UER7
ENST00000266000DAXX-2012606-ENSP00000266000740 (aa)-Q9UER7
ENST00000498030DAXX-210463--- (aa)--
ENST00000374542DAXX-2022613-ENSP00000363668740 (aa)-Q9UER7
ENST00000477370DAXX-208756--- (aa)--
ENST00000446511DAXX-205371-ENSP0000039000848 (aa)-A2AB94
ENST00000477162DAXX-207847--- (aa)--
ENST00000446403DAXX-204702-ENSP00000406008178 (aa)-Q4VX54
ENST00000490173DAXX-209641--- (aa)--
ENST00000414083DAXX-2032355XM_005248860ENSP00000396876665 (aa)XP_005248917Q9UER7
ENST00000468536DAXX-206817--- (aa)--
Gene Model
Click here to download ENSG00000204209's gene model file
Pathways
Pathway IDPathway NameSource
hsa04010MAPK signaling pathwayKEGG
hsa04210ApoptosisKEGG
hsa05014Amyotrophic lateral sclerosis (ALS)KEGG
hsa05168Herpes simplex virus 1 infectionKEGG
Phenotypes
ensgIDTraitpValuePubmed ID
ENSG00000204209Cholesterol4.1100000E-005-
Protein-Protein Interaction (PPI)

Clik here to download ENSG00000204209's network

* RBP PPI network refers to all genes directly bind to RBP
Gene Ontology
Go IDGo_termPubmedIDEvidenceCategory
GO:0000775chromosome, centromeric region10504293.IDAComponent
GO:0001934positive regulation of protein phosphorylation15983381.IGIProcess
GO:0002039p53 binding16845383.IPIFunction
GO:0003713transcription coactivator activity15016915.IDAFunction
GO:0003714transcription corepressor activity12140263.IDAFunction
GO:0003714transcription corepressor activity17081986.IMPFunction
GO:0005515protein binding9215629.9743501.10669754.10698492.11003656.11112409.11483955.11495919.11799127.11948183.12140263.12529400.12953102.14517282.14557665.15016915.15033475.15364927.15572661.15983381.16331268.16569639.16810318.16845383.17362989.18566590.18583933.20185822.20195357.20211137.20651253.20936779.21134643.21573799.21840486.21988832.22102817.22609355.22810586.23260419.23395904.23455924.24209620.24651726.25241761.25416956.26496610.27029610.27107012.27211601.IPIFunction
GO:0005634nucleus15572661.15878163.15983381.17081986.IDAComponent
GO:0005654nucleoplasm-TASComponent
GO:0005730nucleolus-IEAComponent
GO:0005737cytoplasm15572661.TASComponent
GO:0005829cytosol-ISSComponent
GO:0006334nucleosome assembly20504901.20651253.IDAProcess
GO:0006338chromatin remodeling20651253.IDAProcess
GO:0006355regulation of transcription, DNA-templated15878163.IDAProcess
GO:0006915apoptotic process15572661.TASProcess
GO:0007257activation of JUN kinase activity9215629.TASProcess
GO:0008625extrinsic apoptotic signaling pathway via death domain receptors9215629.TASProcess
GO:0016032viral process-IEAProcess
GO:0016604nuclear body-IDAComponent
GO:0016605PML body18566590.IDAComponent
GO:0016605PML body15247905.TASComponent
GO:0019899enzyme binding16845383.IPIFunction
GO:0019901protein kinase binding15983381.IPIFunction
GO:0030295protein kinase activator activity15983381.IGIFunction
GO:0030521androgen receptor signaling pathway15572661.IDAProcess
GO:0031072heat shock protein binding15572661.TASFunction
GO:0031396regulation of protein ubiquitination18566590.IDAProcess
GO:0031625ubiquitin protein ligase binding16845383.IPIFunction
GO:0032183SUMO binding17081986.IPIFunction
GO:0034605cellular response to heat15016915.IDAProcess
GO:0034620cellular response to unfolded protein15016915.IDAProcess
GO:0042393histone binding12140263.20211137.20504901.IDAFunction
GO:0045860positive regulation of protein kinase activity15983381.IGIProcess
GO:0045892negative regulation of transcription, DNA-templated12140263.15572661.IDAProcess
GO:0046982protein heterodimerization activity21134643.IDAFunction
GO:0047485protein N-terminus binding15572661.18566590.IPIFunction
GO:0050681androgen receptor binding15572661.IPIFunction
GO:0071276cellular response to cadmium ion15016915.IDAProcess
GO:0071280cellular response to copper ion15016915.IDAProcess
GO:0072738cellular response to diamide15016915.IDAProcess
GO:1901216positive regulation of neuron death15983381.IGIProcess
GO:1903508positive regulation of nucleic acid-templated transcription-IEAProcess
GO:1903936cellular response to sodium arsenite15016915.IDAProcess
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