Cancer | Chr | Position | Mutation Type | dbSNP | Protein-change | Allele Freq | RBD |
---|---|---|---|---|---|---|---|
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BRCA | |||||||
BRCA | |||||||
CESC | |||||||
CESC | |||||||
CESC | |||||||
CESC | |||||||
CESC | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
ESCA | |||||||
ESCA | |||||||
ESCA | |||||||
ESCA | |||||||
GBM | |||||||
HNSC | |||||||
KIRP | |||||||
LGG | |||||||
LGG | |||||||
LUAD | |||||||
LUAD | |||||||
LUAD | |||||||
LUSC | |||||||
LUSC | |||||||
LUSC | |||||||
LUSC | |||||||
MESO | |||||||
OV | |||||||
PAAD | |||||||
PRAD | |||||||
READ | |||||||
SARC | |||||||
STAD | |||||||
STAD | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCS |
Cancer | Type | Freq | Q-value |
---|---|---|---|
DLBC |
Cancer | P-value | Q-value |
---|---|---|
THYM | ||
SARC | ||
MESO | ||
UCS | ||
ESCA | ||
KIRP | ||
COAD | ||
BLCA | ||
LAML | ||
LIHC | ||
LGG | ||
THCA | ||
LUAD | ||
UVM | ||
OV |
Transcript ID | Name | Length | RefSeq ID | Protein ID | Length | RefSeq ID | UniportKB ID |
---|---|---|---|---|---|---|---|
ENST00000375650 | HSPA1B-201 | 2521 | - | ENSP00000364801 | 641 (aa) | - | P0DMV9 |
Pathway ID | Pathway Name | Source |
---|---|---|
hsa03040 | Spliceosome | KEGG |
hsa04010 | MAPK signaling pathway | KEGG |
hsa04141 | Protein processing in endoplasmic reticulum | KEGG |
hsa04144 | Endocytosis | KEGG |
hsa04213 | Longevity regulating pathway - multiple species | KEGG |
hsa04612 | Antigen processing and presentation | KEGG |
hsa04915 | Estrogen signaling pathway | KEGG |
hsa05134 | Legionellosis | KEGG |
hsa05145 | Toxoplasmosis | KEGG |
hsa05162 | Measles | KEGG |
Ensembl ID | Gene Symbol | Coverage | Identiy | Ortholog | Gene Symbol | Coverage | Identiy | Species |
---|---|---|---|---|---|---|---|---|
ENSG00000204388 | HSPA1B | 100 | 93.458 | ENSMUSG00000090877 | Hspa1b | 95 | 95.745 | Mus_musculus |
Go ID | Go_term | PubmedID | Evidence | Category |
---|---|---|---|---|
GO:0000151 | ubiquitin ligase complex | 12150907. | IDA | Component |
GO:0001618 | virus receptor activity | - | IEA | Function |
GO:0001664 | G protein-coupled receptor binding | 12150907. | IDA | Function |
GO:0003723 | RNA binding | 22658674.22681889. | HDA | Function |
GO:0005102 | signaling receptor binding | 24790089. | IPI | Function |
GO:0005515 | protein binding | 15603737.15671022.18975920.21081504.22528486.23349634.24318877.27133716.27137183.27708256.28298427. | IPI | Function |
GO:0005524 | ATP binding | 21873635. | IBA | Function |
GO:0005524 | ATP binding | 23921388. | IDA | Function |
GO:0005576 | extracellular region | - | TAS | Component |
GO:0005634 | nucleus | 21873635. | IBA | Component |
GO:0005634 | nucleus | 10205060.17167422. | IDA | Component |
GO:0005654 | nucleoplasm | - | TAS | Component |
GO:0005737 | cytoplasm | 21873635. | IBA | Component |
GO:0005737 | cytoplasm | 9553041.10859165.24061851.24790089. | IDA | Component |
GO:0005737 | cytoplasm | 16130169. | TAS | Component |
GO:0005739 | mitochondrion | 16130169. | TAS | Component |
GO:0005783 | endoplasmic reticulum | 16130169. | TAS | Component |
GO:0005813 | centrosome | 27137183. | IDA | Component |
GO:0005814 | centriole | 24061851. | IDA | Component |
GO:0005829 | cytosol | 21873635. | IBA | Component |
GO:0005829 | cytosol | 21231916. | IDA | Component |
GO:0005829 | cytosol | - | TAS | Component |
GO:0005925 | focal adhesion | 21423176. | HDA | Component |
GO:0006402 | mRNA catabolic process | 10205060. | IDA | Process |
GO:0006986 | response to unfolded protein | 21873635. | IBA | Process |
GO:0008180 | COP9 signalosome | 21873635. | IBA | Component |
GO:0008285 | negative regulation of cell proliferation | 9553041. | IMP | Process |
GO:0010628 | positive regulation of gene expression | 25281747. | IMP | Process |
GO:0010941 | regulation of cell death | 21231916. | IMP | Process |
GO:0016234 | inclusion body | 15603737. | IDA | Component |
GO:0016235 | aggresome | 15885686. | IDA | Component |
GO:0016607 | nuclear speck | 9553041. | IDA | Component |
GO:0016887 | ATPase activity | 21873635. | IBA | Function |
GO:0016887 | ATPase activity | 23921388. | IDA | Function |
GO:0019899 | enzyme binding | 23921388. | IPI | Function |
GO:0030308 | negative regulation of cell growth | 9553041. | IMP | Process |
GO:0031072 | heat shock protein binding | 21873635. | IBA | Function |
GO:0031072 | heat shock protein binding | 17182002.21231916.23921388. | IPI | Function |
GO:0031396 | regulation of protein ubiquitination | 16809764. | IDA | Process |
GO:0031397 | negative regulation of protein ubiquitination | 12150907. | IDA | Process |
GO:0031625 | ubiquitin protein ligase binding | 21873635. | IBA | Function |
GO:0031625 | ubiquitin protein ligase binding | 12150907.15603737. | IPI | Function |
GO:0031982 | vesicle | 19190083. | HDA | Component |
GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | 21873635. | IBA | Process |
GO:0032757 | positive regulation of interleukin-8 production | 24790089. | IMP | Process |
GO:0032991 | protein-containing complex | 21873635. | IBA | Component |
GO:0032991 | protein-containing complex | 23349634. | IDA | Component |
GO:0034599 | cellular response to oxidative stress | 24252804. | TAS | Process |
GO:0034605 | cellular response to heat | 21873635. | IBA | Process |
GO:0034605 | cellular response to heat | 24061851. | IDA | Process |
GO:0034620 | cellular response to unfolded protein | 21873635. | IBA | Process |
GO:0042026 | protein refolding | 21873635. | IBA | Process |
GO:0042026 | protein refolding | 15603737.21231916. | IDA | Process |
GO:0042026 | protein refolding | 27708256. | IMP | Process |
GO:0042623 | ATPase activity, coupled | 21873635. | IBA | Function |
GO:0042623 | ATPase activity, coupled | 21231916. | IDA | Function |
GO:0042623 | ATPase activity, coupled | - | TAS | Function |
GO:0042826 | histone deacetylase binding | 16809764. | IPI | Function |
GO:0043066 | negative regulation of apoptotic process | 17167422. | IMP | Process |
GO:0043066 | negative regulation of apoptotic process | 16130169. | TAS | Process |
GO:0043312 | neutrophil degranulation | - | TAS | Process |
GO:0044183 | protein binding involved in protein folding | 21873635. | IBA | Function |
GO:0044183 | protein binding involved in protein folding | 15603737. | IDA | Function |
GO:0045648 | positive regulation of erythrocyte differentiation | 17167422. | IMP | Process |
GO:0046034 | ATP metabolic process | 23921388. | IDA | Process |
GO:0046718 | viral entry into host cell | - | IEA | Process |
GO:0047485 | protein N-terminus binding | 9553041. | IPI | Function |
GO:0048471 | perinuclear region of cytoplasm | 10205060.15603737. | IDA | Component |
GO:0050821 | protein stabilization | 24790089. | IMP | Process |
GO:0050821 | protein stabilization | 24252804. | TAS | Process |
GO:0051082 | unfolded protein binding | 21873635. | IBA | Function |
GO:0051082 | unfolded protein binding | 21231916. | IDA | Function |
GO:0051082 | unfolded protein binding | 12150907. | NAS | Function |
GO:0051082 | unfolded protein binding | 16130169. | TAS | Function |
GO:0051085 | chaperone cofactor-dependent protein refolding | 21873635. | IBA | Process |
GO:0051092 | positive regulation of NF-kappaB transcription factor activity | 24790089. | IMP | Process |
GO:0051787 | misfolded protein binding | 21873635. | IBA | Function |
GO:0055131 | C3HC4-type RING finger domain binding | 25281747. | IPI | Function |
GO:0060548 | negative regulation of cell death | 12150907. | IDA | Process |
GO:0060548 | negative regulation of cell death | 21231916. | IMP | Process |
GO:0070062 | extracellular exosome | 19199708.20458337.23533145. | HDA | Component |
GO:0070370 | cellular heat acclimation | 21231916. | IMP | Process |
GO:0070434 | positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway | 24790089. | IMP | Process |
GO:0072562 | blood microparticle | 22516433. | HDA | Component |
GO:0090063 | positive regulation of microtubule nucleation | 27137183. | IMP | Process |
GO:0090084 | negative regulation of inclusion body assembly | 15603737.21231916. | IDA | Process |
GO:1900034 | regulation of cellular response to heat | - | TAS | Process |
GO:1901673 | regulation of mitotic spindle assembly | 21873635. | IBA | Process |
GO:1901673 | regulation of mitotic spindle assembly | 27137183. | IMP | Process |
GO:1903265 | positive regulation of tumor necrosis factor-mediated signaling pathway | 24790089. | IMP | Process |
GO:1904813 | ficolin-1-rich granule lumen | - | TAS | Component |
GO:1990904 | ribonucleoprotein complex | 17289661. | IDA | Component |
GO:2001240 | negative regulation of extrinsic apoptotic signaling pathway in absence of ligand | 17167422. | IMP | Process |