Cancer | Chr | Position | Mutation Type | dbSNP | Protein-change | Allele Freq | RBD |
---|---|---|---|---|---|---|---|
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
BLCA | |||||||
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BLCA | |||||||
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BRCA | |||||||
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BRCA | |||||||
BRCA | |||||||
CESC | |||||||
CESC | |||||||
CESC | |||||||
CESC | |||||||
CESC | |||||||
CESC | |||||||
CESC | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
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COAD | |||||||
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COAD | |||||||
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COAD | |||||||
COAD | |||||||
COAD | |||||||
COAD | |||||||
ESCA | |||||||
ESCA | |||||||
ESCA | |||||||
GBM | |||||||
GBM | |||||||
GBM | |||||||
GBM | |||||||
GBM | |||||||
GBM | |||||||
HNSC | |||||||
HNSC | |||||||
HNSC | |||||||
KIRC | |||||||
KIRP | |||||||
LGG | |||||||
LGG | |||||||
LIHC | |||||||
LIHC | |||||||
LIHC | |||||||
LIHC | |||||||
LIHC | |||||||
LIHC | |||||||
LUAD | |||||||
LUAD | |||||||
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LUAD | |||||||
LUAD | |||||||
LUAD | |||||||
LUAD | |||||||
LUAD | |||||||
LUAD | |||||||
LUAD | |||||||
LUSC | |||||||
LUSC | |||||||
LUSC | |||||||
LUSC | |||||||
LUSC | |||||||
LUSC | |||||||
LUSC | |||||||
LUSC | |||||||
LUSC | |||||||
LUSC | |||||||
LUSC | |||||||
LUSC | |||||||
OV | |||||||
OV | |||||||
OV | |||||||
OV | |||||||
OV | |||||||
OV | |||||||
PAAD | |||||||
PRAD | |||||||
PRAD | |||||||
PRAD | |||||||
READ | |||||||
READ | |||||||
READ | |||||||
SARC | |||||||
SARC | |||||||
SARC | |||||||
SARC | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
STAD | |||||||
THYM | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCS |
Cancer | Type | Freq | Q-value |
---|---|---|---|
DLBC |
Cancer | P-value | Q-value |
---|---|---|
THYM | ||
KIRC | ||
SARC | ||
SKCM | ||
TGCT | ||
PAAD | ||
READ | ||
LAML | ||
UCEC | ||
LIHC | ||
UVM |
Transcript ID | Name | Length | RefSeq ID | Protein ID | Length | RefSeq ID | UniportKB ID |
---|---|---|---|---|---|---|---|
ENST00000424176 | BAG6-239 | 747 | - | ENSP00000391783 | 215 (aa) | - | F6XTU0 |
ENST00000438149 | BAG6-246 | 714 | - | ENSP00000410280 | 238 (aa) | - | H0Y759 |
ENST00000428326 | BAG6-241 | 1051 | - | ENSP00000413561 | 262 (aa) | - | F6U341 |
ENST00000362049 | BAG6-235 | 3626 | XM_017011291 | ENSP00000354875 | 1077 (aa) | XP_016866780 | P46379 |
ENST00000465348 | BAG6-260 | 639 | - | - | - (aa) | - | - |
ENST00000462875 | BAG6-257 | 972 | - | - | - (aa) | - | - |
ENST00000464126 | BAG6-258 | 609 | - | - | - (aa) | - | - |
ENST00000441054 | BAG6-248 | 654 | - | ENSP00000406302 | 206 (aa) | - | F6U1F2 |
ENST00000456286 | BAG6-254 | 807 | - | ENSP00000406436 | 197 (aa) | - | F6UR09 |
ENST00000435080 | BAG6-244 | 1710 | - | ENSP00000411083 | 515 (aa) | - | F6S6P2 |
ENST00000464869 | BAG6-259 | 488 | - | - | - (aa) | - | - |
ENST00000470875 | BAG6-262 | 1000 | - | - | - (aa) | - | - |
ENST00000211379 | BAG6-234 | 3779 | XM_011514892 | ENSP00000211379 | 1126 (aa) | XP_011513194 | P46379 |
ENST00000422948 | BAG6-238 | 513 | - | ENSP00000413225 | 136 (aa) | - | H0Y4L1 |
ENST00000453833 | BAG6-252 | 554 | - | ENSP00000406434 | 185 (aa) | - | H0Y7K4 |
ENST00000469182 | BAG6-261 | 653 | - | - | - (aa) | - | - |
ENST00000451898 | BAG6-250 | 993 | - | ENSP00000391613 | 243 (aa) | - | A0A1B0GX79 |
ENST00000434444 | BAG6-243 | 766 | - | ENSP00000394856 | 244 (aa) | - | F6WML8 |
ENST00000437771 | BAG6-245 | 2407 | - | ENSP00000397978 | 742 (aa) | - | X6REW1 |
ENST00000456622 | BAG6-255 | 859 | - | ENSP00000401031 | 244 (aa) | - | F6WML8 |
ENST00000462682 | BAG6-256 | 349 | - | - | - (aa) | - | - |
ENST00000441793 | BAG6-249 | 783 | - | ENSP00000416633 | 226 (aa) | - | H0Y710 |
ENST00000454165 | BAG6-253 | 544 | - | ENSP00000396503 | 158 (aa) | - | F6TC96 |
ENST00000375976 | BAG6-237 | 3644 | XM_017011277 | ENSP00000365143 | 1126 (aa) | XP_016866766 | P46379 |
ENST00000452994 | BAG6-251 | 880 | - | ENSP00000404971 | 262 (aa) | - | F6U341 |
ENST00000424480 | BAG6-240 | 1056 | - | ENSP00000411043 | 258 (aa) | - | F6VEM6 |
ENST00000439687 | BAG6-247 | 3104 | - | ENSP00000402856 | 903 (aa) | - | P46379 |
ENST00000433828 | BAG6-242 | 902 | - | ENSP00000388244 | 259 (aa) | - | F6X9W3 |
ENST00000375964 | BAG6-236 | 3815 | - | ENSP00000365131 | 1132 (aa) | - | P46379 |
ensgID | Trait | pValue | Pubmed ID |
---|---|---|---|
ENSG00000204463 | Lupus Erythematosus, Systemic | 1.24541E-9 | 18204098 |
ENSG00000204463 | Lupus Erythematosus, Systemic | 3.8264E-11 | 18204098 |
ENSG00000204463 | Lupus Erythematosus, Systemic | 3.3307E-16 | 18204098 |
ENSG00000204463 | Breast Neoplasms | 9.724E-20 | 17660530 |
ENSG00000204463 | Diabetes Mellitus, Type 1 | 2.79E-119 | 19430480 |
ENSG00000204463 | Diabetes Mellitus, Type 1 | 2.62E-83 | 19430480 |
ENSG00000204463 | Diabetes Mellitus, Type 1 | 1.52E-71 | 19430480 |
ENSG00000204463 | Diabetes Mellitus, Type 1 | 6.29E-135 | 19430480 |
ENSG00000204463 | Lupus Erythematosus, Systemic | 4.53E-8 | 18204446 |
ENSG00000204463 | Platelet Function Tests | 3.1500000E-006 | - |
ENSG00000204463 | Platelet Function Tests | 3.1500000E-006 | - |
ENSG00000204463 | Blood Pressure | 2E-11 | 21909115 |
ENSG00000204463 | Adenocarcinoma of lung | 5E-12 | 19836008 |
ENSG00000204463 | Lung Neoplasms | 4E-10 | 19654303 |
ENSG00000204463 | Hypertension | 1E-10 | 21909115 |
ENSG00000204463 | Blood Pressure | 3E-11 | 21909115 |
ENSG00000204463 | Lung Neoplasms | 5E-10 | 18978787 |
ENSG00000204463 | Arthritis, Rheumatoid | 3E-10 | 21844665 |
ensgID | SNP | Chromosome | Position | SNP-risk | Trait | PubmedID | 95% CI | Or or BEAT | EFO ID |
---|---|---|---|---|---|---|---|---|---|
ENSG00000204463 | rs805303 | 6 | 31648589 | A | Diastolic blood pressure | 28739976 | [0.13-0.33] unit decrease | 0.23 | EFO_0006336 |
ENSG00000204463 | rs805303 | 6 | 31648589 | A | Systolic blood pressure | 28739976 | [0.21-0.53] unit decrease | 0.368 | EFO_0006335 |
ENSG00000204463 | rs115441327 | 6 | 31645962 | C | Small cell lung carcinoma | 28604730 | [1.087902659-1.240674335] | 1.1617801 | EFO_0000702 |
ENSG00000204463 | rs805303 | 6 | 31648589 | A | Systolic blood pressure | 27618447 | unit decrease | 0.0174 | EFO_0006335 |
ENSG00000204463 | rs1077393 | 6 | 31642752 | A | Feeling worry | 29500382 | unit decrease | 6.267 | EFO_0009589 |
ENSG00000204463 | rs805303 | 6 | 31648589 | G | Diastolic blood pressure | 21909115 | [NR] mmHg increase | 0.228 | EFO_0006336 |
ENSG00000204463 | rs805303 | 6 | 31648589 | G | Hypertension | 21909115 | [NR] unit increase | 0.054 | EFO_0000537 |
ENSG00000204463 | rs805303 | 6 | 31648589 | G | Systolic blood pressure | 21909115 | [NR] mmHg increase | 0.376 | EFO_0006335 |
ENSG00000204463 | rs1077393 | 6 | 31642752 | A | Neurociticism | 29500382 | z score decrease | 5.65 | EFO_0007660 |
ENSG00000204463 | rs115872194 | 6 | 31639897 | ? | Psoriatic arthritis | 30552173 | [NR] z-score increase | 6.12 | EFO_0003778 |
Ensembl ID | Gene Symbol | Coverage | Identiy | Ortholog | Gene Symbol | Coverage | Identiy | Species |
---|---|---|---|---|---|---|---|---|
ENSG00000204463 | BAG6 | 99 | 97.778 | ENSMUSG00000024392 | Bag6 | 100 | 93.913 | Mus_musculus |
Go ID | Go_term | PubmedID | Evidence | Category |
---|---|---|---|---|
GO:0001822 | kidney development | - | ISS | Process |
GO:0002429 | immune response-activating cell surface receptor signaling pathway | 18852879. | IDA | Process |
GO:0005102 | signaling receptor binding | 18852879. | IPI | Function |
GO:0005515 | protein binding | 14667819.14960581.16189514.17403783.18765639.18852879.21903422.22807449.23246001.25036637.25416956.25535373.25713138.26876100.29042515. | IPI | Function |
GO:0005634 | nucleus | 14960581.17403783.21636303.29042515. | IDA | Component |
GO:0005654 | nucleoplasm | - | IDA | Component |
GO:0005737 | cytoplasm | 21636303. | IDA | Component |
GO:0005829 | cytosol | 17403783.20676083.23246001.29042515. | IDA | Component |
GO:0006325 | chromatin organization | - | IEA | Process |
GO:0006511 | ubiquitin-dependent protein catabolic process | - | ISS | Process |
GO:0006915 | apoptotic process | 14960581. | IDA | Process |
GO:0007130 | synaptonemal complex assembly | - | ISS | Process |
GO:0007283 | spermatogenesis | - | ISS | Process |
GO:0007420 | brain development | - | ISS | Process |
GO:0010498 | proteasomal protein catabolic process | 26565908. | IMP | Process |
GO:0016020 | membrane | 19946888. | HDA | Component |
GO:0016020 | membrane | 23246001. | IDA | Component |
GO:0018393 | internal peptidyl-lysine acetylation | 17403783. | IDA | Process |
GO:0030101 | natural killer cell activation | 18852879. | IDA | Process |
GO:0030154 | cell differentiation | - | IEA | Process |
GO:0030324 | lung development | - | ISS | Process |
GO:0030433 | ubiquitin-dependent ERAD pathway | 23129660.24981174. | IDA | Process |
GO:0030433 | ubiquitin-dependent ERAD pathway | 26565908. | IMP | Process |
GO:0030544 | Hsp70 protein binding | - | IEA | Function |
GO:0031593 | polyubiquitin modification-dependent protein binding | - | ISS | Function |
GO:0031625 | ubiquitin protein ligase binding | 21636303.24981174. | IPI | Function |
GO:0032435 | negative regulation of proteasomal ubiquitin-dependent protein catabolic process | - | ISS | Process |
GO:0042127 | regulation of cell proliferation | - | IEA | Process |
GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | 17403783. | IMP | Process |
GO:0043022 | ribosome binding | 20676083. | IDA | Function |
GO:0043066 | negative regulation of apoptotic process | - | IEA | Process |
GO:0043231 | intracellular membrane-bounded organelle | - | IDA | Component |
GO:0045861 | negative regulation of proteolysis | - | ISS | Process |
GO:0045995 | regulation of embryonic development | - | ISS | Process |
GO:0050821 | protein stabilization | - | ISS | Process |
GO:0051787 | misfolded protein binding | 21636303. | IDA | Function |
GO:0061857 | endoplasmic reticulum stress-induced pre-emptive quality control | 26565908. | IMP | Process |
GO:0070059 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | - | ISS | Process |
GO:0070062 | extracellular exosome | 18852879. | IDA | Component |
GO:0070628 | proteasome binding | - | ISS | Function |
GO:0071712 | ER-associated misfolded protein catabolic process | 23129660.24981174. | IDA | Process |
GO:0071816 | tail-anchored membrane protein insertion into ER membrane | 20676083.25535373. | IDA | Process |
GO:0071818 | BAT3 complex | 20676083.21636303.25535373. | IDA | Component |
GO:1904294 | positive regulation of ERAD pathway | 24424410. | IMP | Process |
GO:1904378 | maintenance of unfolded protein involved in ERAD pathway | 21636303. | IMP | Process |
GO:1904379 | protein localization to cytosolic proteasome complex involved in ERAD pathway | 21636303. | NAS | Process |
GO:1990381 | ubiquitin-specific protease binding | 24424410. | IPI | Function |