24085291 | Inhibition of Snail1-DNA-PKcs protein-protein interface sensitizes cancer cells and inhibits tumor metastasis. | J Biol Chem | 2013 Nov 8 | Kang GY | doi: 10.1074/jbc.M113.479840 |
27856181 | Down-regulation of protein kinase, DNA-activated, catalytic polypeptide attenuates tumor progression and is an independent prognostic predictor of survival in prostate cancer. | Urol Oncol | 2017 Mar | Zhang X | doi: 10.1016/j.urolonc.2016.10.012 |
27629740 | Expression of Interactive Genes Associated with Apoptosis and Their Prognostic Value for Ovarian Serous Adenocarcinoma. | Adv Clin Exp Med | 2016 May-Jun | Shin K | doi: 10.17219/acem/62540. |
17626748 | [Potentials of DNA-PKcs, Ku80, and ATM in enhancing radiosensitivity of cervical carcinoma cells]. | Ai Zheng | 2007 Jul | Zhuang L | - |
18246802 | [Expression of GLUT-1, p63 and DNA-Pkcs in serous ovarian tumors and their significance]. | Zhonghua Zhong Liu Za Zhi | 2007 Sep | Shao SL | - |
26065416 | Proteomic Identification of DNA-PK Involvement within the RET Signaling Pathway. | PLoS One | 2015 Jun 11 | Burdine LJ | doi: 10.1371/journal.pone.0127943 |
15286704 | Effects of novel inhibitors of poly(ADP-ribose) polymerase-1 and the DNA-dependent protein kinase on enzyme activities and DNA repair. | Oncogene | 2004 Sep 23 | Veuger SJ | - |
24662822 | DNA-PK/Chk2 induces centrosome amplification during prolonged replication stress. | Oncogene | 2015 Mar 5 | Wang CY | doi: 10.1038/onc.2014.74 |
25823795 | Knockdown of microRNA-1323 restores sensitivity to radiation by suppression of PRKDC activity in radiation-resistant lung cancer cells. | Oncol Rep | 2015 Jun | Li Y | doi: 10.3892/or.2015.3884 |
23108991 | Current evidence on the relationship between three polymorphisms in the XRCC7 gene and cancer risk. | Mol Biol Rep | 2013 Jan | Zhang J | doi: 10.1007/s11033-012-2018-9 |
29397516 | Role of polymorphic XRCC6 (Ku70)/XRCC7 (DNA-PKcs) genes towards susceptibility and prognosis of lung cancer patients undergoing platinum based doublet chemotherapy. | Mol Biol Rep | 2018 Jun | Singh A | doi: 10.1007/s11033-018-4158-z |
25925375 | The Catalytic Subunit of DNA-Dependent Protein Kinase Coordinates with Polo-Like Kinase 1 to Facilitate Mitotic Entry. | Neoplasia | 2015 Apr | Lee KJ | doi: 10.1016/j.neo.2015.02.004. |
23505488 | Inactivation of DNA-dependent protein kinase promotes heat-induced apoptosis independently of heat-shock protein induction in human cancer cell lines. | PLoS One | 2013 | Okazawa S | doi: 10.1371/journal.pone.0058325 |
17786318 | Altered expression of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) during gastric carcinogenesis and its clinical implications on gastric cancer. | Int J Oncol | 2007 Oct | Lee HS | - |
27499034 | Downregulation of DNA-PKcs suppresses P-gp expression via inhibition of the Akt/NF-??B pathway in CD133-positive osteosarcoma MG-63 cells. | Oncol Rep | 2016 Oct | Li K | doi: 10.3892/or.2016.4991 |
26175416 | DNA-PKcs-Mediated Transcriptional Regulation Drives Prostate Cancer Progression and Metastasis. | Cancer Cell | 2015 Jul 13 | Goodwin JF | doi: 10.1016/j.ccell.2015.06.004. |
16000400 | The association of DNA-dependent protein kinase activity with chromosomal instability and risk of cancer. | Carcinogenesis | 2006 Jan | Someya M | - |
25503126 | Genotype of DNA double-strand break repair gene XRCC7 is associated with lung cancer risk in Taiwan males and smokers. | Anticancer Res | 2014 Dec | Hsia TC | - |
25078033 | TRIP13 promotes error-prone nonhomologous end joining and induces chemoresistance in head and neck cancer. | Nat Commun | 2014 Jul 31 | Banerjee R | doi: 10.1038/ncomms5527. |
24013362 | DNA-PKcs inhibition sensitizes cancer cells to carbon-ion irradiation via telomere capping disruption. | PLoS One | 2013 Aug 27 | Zhou X | doi: 10.1371/journal.pone.0072641 |
19815090 | Do DNA repair genes OGG1, XRCC3 and XRCC7 have an impact on susceptibility to bladder cancer in the North Indian population? | Mutat Res | 2009 Nov-Dec | Gangwar R | doi: 10.1016/j.mrgentox.2009.09.008 |
26017556 | DNA-PKcs plays role in cancer metastasis through regulation of secreted proteins involved in migration and invasion. | Cell Cycle | 2015 | Kotula E | doi: 10.1080/15384101.2015.1026522. |
18550272 | Processing of clustered DNA damage in human breast cancer cells MCF-7 with partial DNA-PKcs deficiency. | Cancer Lett | 2008 Sep 28 | Peddi P | doi: 10.1016/j.canlet.2008.04.049 |
23183621 | The role of Ile3434Thr XRCC7 gene polymorphism in differentiated thyroid cancer risk in an Iranian population. | Iran Biomed J | 2012 | Rahimi M | - |
17441731 | Phosphorylation of RNA helicase A by DNA-dependent protein kinase is indispensable for expression of the MDR1 gene product P-glycoprotein in multidrug-resistant human leukemia cells. | Biochemistry | 2007 May 15 | Zhong X | - |
19624897 | [Correlation of DNA-dependent protein kinase catalytic subunit expression to radiosensitivity of non-small cell lung cancer cell lines]. | Ai Zheng | 2009 Jul | Pan Y | - |
24535266 | The rs7003908 (T>G) polymorphism in the XRCC7 gene and the risk of cancers. | Mol Biol Rep | 2014 Jun | Xiao M | doi: 10.1007/s11033-014-3220-8 |
17786349 | Association of DNA-PK activity and radiation-induced NBS1 foci formation in lymphocytes with clinical malignancy in breast cancer patients. | Oncol Rep | 2007 Oct | Someya M | - |
22634101 | Genetic variation in DNA repair gene XRCC7 (G6721T) and susceptibility to breast cancer. | Gene | 2012 Aug 15 | Nasiri M | doi: 10.1016/j.gene.2012.04.065 |
20219974 | Interaction of the double-strand break repair kinase DNA-PK and estrogen receptor-alpha. | Mol Biol Cell | 2010 May 1 | Medunjanin S | doi: 10.1091/mbc.E09-08-0724 |
23603433 | Instability at the FRA8I common fragile site disrupts the genomic integrity of the KIAA0146, CEBPD and PRKDC genes in colorectal cancer. | Cancer Lett | 2013 Aug 9 | Brueckner LM | doi: 10.1016/j.canlet.2013.04.007 |
18422577 | Genetic variants of the XRCC7 gene involved in DNA repair and risk of human bladder cancer. | Int J Urol | 2008 Jun | Wang SY | doi: 10.1111/j.1442-2042.2008.02049.x |
18644989 | Targeting of AKT1 enhances radiation toxicity of human tumor cells by inhibiting DNA-PKcs-dependent DNA double-strand break repair. | Mol Cancer Ther | 2008 Jul | Toulany M | doi: 10.1158/1535-7163.MCT-07-2200. |
18508926 | DNA-ligase IV and DNA-protein kinase play a critical role in deficient caspases activation in apoptosis-resistant cancer cells by using doxorubicin. | Mol Biol Cell | 2008 Aug | Friesen C | doi: 10.1091/mbc.E08-03-0306 |
20590474 | Polymorphic variants of DNA repair gene XRCC3 and XRCC7 and risk of prostate cancer: a study from North Indian population. | DNA Cell Biol | 2010 Nov | Mandal RK | doi: 10.1089/dna.2010.1047 |
23098447 | Association between XRCC5, 6 and 7 gene polymorphisms and the risk of breast cancer: a HuGE review and meta-analysis. | Asian Pac J Cancer Prev | 2012 | Zhou LP | - |
21559021 | The association of DNA-dependent protein kinase activity of peripheral blood lymphocytes with prognosis of cancer. | Br J Cancer | 2011 May 24 | Someya M | doi: 10.1038/bjc.2011.158 |
27988337 | micorRNA-101 silences DNA-PKcs and sensitizes pancreatic cancer cells to gemcitabine. | Biochem Biophys Res Commun | 2017 Jan 29 | Hu H | doi: 10.1016/j.bbrc.2016.12.074 |
27693638 | DNA-PKcs, a novel functional target of acriflavine, mediates acriflavine's p53-dependent synergistic anti-tumor efficiency with melphalan. | Cancer Lett | 2016 Dec 1 | Cao J | doi: 10.1016/j.canlet.2016.09.029 |
28399576 | Local tumor control and DNA-PK activity of peripheral blood lymphocytes in prostate cancer patients receiving radiotherapy. | J Radiat Res | 2017 Mar 1 | Someya M | doi: 10.1093/jrr/rrw099. |
28450160 | A novel histone deacetylase inhibitor TMU-35435 enhances etoposide cytotoxicity through the proteasomal degradation of DNA-PKcs in triple-negative breast cancer. | Cancer Lett | 2017 Aug 1 | Wu YH | doi: 10.1016/j.canlet.2017.04.023 |
29150048 | DNA-dependent protein kinase modulates the anti-cancer properties of silver nanoparticles in human cancer cells. | Mutat Res | 2017 Dec | Lim HK | doi: 10.1016/j.mrgentox.2017.10.001 |
28498431 | PRKDC regulates chemosensitivity and is a potential prognostic and predictive marker of response to adjuvant chemotherapy in breast cancer patients. | Oncol Rep | 2017 Jun | Sun G | doi: 10.3892/or.2017.5634 |
28970727 | Aberrant DNA-PKcs and ERGIC1 expression may be involved in initiation of gastric cancer. | World J Gastroenterol | 2017 Sep 7 | Wang FR | doi: 10.3748/wjg.v23.i33.6119. |
29084207 | Upregulation of the ALDOA/DNA-PK/p53 pathway by dietary restriction suppresses tumor growth. | Oncogene | 2018 Feb 22 | Ma D | doi: 10.1038/onc.2017.398 |