EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
24085291	Inhibition of Snail1-DNA-PKcs protein-protein interface sensitizes cancer cells and inhibits tumor metastasis.	J Biol Chem	2013 Nov 8	Kang GY	doi: 10.1074/jbc.M113.479840
27856181	Down-regulation of protein kinase, DNA-activated, catalytic polypeptide attenuates tumor progression and is an independent prognostic predictor of survival in prostate cancer.	Urol Oncol	2017 Mar	Zhang X	doi: 10.1016/j.urolonc.2016.10.012
27629740	Expression of Interactive Genes Associated with Apoptosis and Their Prognostic Value for Ovarian Serous Adenocarcinoma.	Adv Clin Exp Med	2016 May-Jun	Shin K	doi: 10.17219/acem/62540.
17626748	[Potentials of DNA-PKcs, Ku80, and ATM in enhancing radiosensitivity of cervical carcinoma cells].	Ai Zheng	2007 Jul	Zhuang L	-
18246802	[Expression of GLUT-1, p63 and DNA-Pkcs in serous ovarian tumors and their significance].	Zhonghua Zhong Liu Za Zhi	2007 Sep	Shao SL	-
26065416	Proteomic Identification of DNA-PK Involvement within the RET Signaling Pathway.	PLoS One	2015 Jun 11	Burdine LJ	doi: 10.1371/journal.pone.0127943
15286704	Effects of novel inhibitors of poly(ADP-ribose) polymerase-1 and the DNA-dependent protein kinase on enzyme activities and DNA repair.	Oncogene	2004 Sep 23	Veuger SJ	-
24662822	DNA-PK/Chk2 induces centrosome amplification during prolonged replication stress.	Oncogene	2015 Mar 5	Wang CY	doi: 10.1038/onc.2014.74
25823795	Knockdown of microRNA-1323 restores sensitivity to radiation by suppression of PRKDC activity in radiation-resistant lung cancer cells.	Oncol Rep	2015 Jun	Li Y	doi: 10.3892/or.2015.3884
23108991	Current evidence on the relationship between three polymorphisms in the XRCC7 gene and cancer risk.	Mol Biol Rep	2013 Jan	Zhang J	doi: 10.1007/s11033-012-2018-9
29397516	Role of polymorphic XRCC6 (Ku70)/XRCC7 (DNA-PKcs) genes towards susceptibility and prognosis of lung cancer patients undergoing platinum based doublet chemotherapy.	Mol Biol Rep	2018 Jun	Singh A	doi: 10.1007/s11033-018-4158-z
25925375	The Catalytic Subunit of DNA-Dependent Protein Kinase Coordinates with Polo-Like Kinase 1 to Facilitate Mitotic Entry.	Neoplasia	2015 Apr	Lee KJ	doi: 10.1016/j.neo.2015.02.004.
23505488	Inactivation of DNA-dependent protein kinase promotes heat-induced apoptosis independently of heat-shock protein induction in human cancer cell lines.	PLoS One	2013	Okazawa S	doi: 10.1371/journal.pone.0058325
17786318	Altered expression of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) during gastric carcinogenesis and its clinical implications on gastric cancer.	Int J Oncol	2007 Oct	Lee HS	-
27499034	Downregulation of DNA-PKcs suppresses P-gp expression via inhibition of the Akt/NF-??B pathway in CD133-positive osteosarcoma MG-63 cells.	Oncol Rep	2016 Oct	Li K	doi: 10.3892/or.2016.4991
26175416	DNA-PKcs-Mediated Transcriptional Regulation Drives Prostate Cancer Progression and Metastasis.	Cancer Cell	2015 Jul 13	Goodwin JF	doi: 10.1016/j.ccell.2015.06.004.
16000400	The association of DNA-dependent protein kinase activity with chromosomal instability and risk of cancer.	Carcinogenesis	2006 Jan	Someya M	-
25503126	Genotype of DNA double-strand break repair gene XRCC7 is associated with lung cancer risk in Taiwan males and smokers.	Anticancer Res	2014 Dec	Hsia TC	-
25078033	TRIP13 promotes error-prone nonhomologous end joining and induces chemoresistance in head and neck cancer.	Nat Commun	2014 Jul 31	Banerjee R	doi: 10.1038/ncomms5527.
24013362	DNA-PKcs inhibition sensitizes cancer cells to carbon-ion irradiation via telomere capping disruption.	PLoS One	2013 Aug 27	Zhou X	doi: 10.1371/journal.pone.0072641
19815090	Do DNA repair genes OGG1, XRCC3 and XRCC7 have an impact on susceptibility to bladder cancer in the North Indian population?	Mutat Res	2009 Nov-Dec	Gangwar R	doi: 10.1016/j.mrgentox.2009.09.008
26017556	DNA-PKcs plays role in cancer metastasis through regulation of secreted proteins involved in migration and invasion.	Cell Cycle	2015	Kotula E	doi: 10.1080/15384101.2015.1026522.
18550272	Processing of clustered DNA damage in human breast cancer cells MCF-7 with partial DNA-PKcs deficiency.	Cancer Lett	2008 Sep 28	Peddi P	doi: 10.1016/j.canlet.2008.04.049
23183621	The role of Ile3434Thr XRCC7 gene polymorphism in differentiated thyroid cancer risk in an Iranian population.	Iran Biomed J	2012	Rahimi M	-
17441731	Phosphorylation of RNA helicase A by DNA-dependent protein kinase is indispensable for expression of the MDR1 gene product P-glycoprotein in multidrug-resistant human leukemia cells.	Biochemistry	2007 May 15	Zhong X	-
19624897	[Correlation of DNA-dependent protein kinase catalytic subunit expression to radiosensitivity of non-small cell lung cancer cell lines].	Ai Zheng	2009 Jul	Pan Y	-
24535266	The rs7003908 (T>G) polymorphism in the XRCC7 gene and the risk of cancers.	Mol Biol Rep	2014 Jun	Xiao M	doi: 10.1007/s11033-014-3220-8
17786349	Association of DNA-PK activity and radiation-induced NBS1 foci formation in lymphocytes with clinical malignancy in breast cancer patients.	Oncol Rep	2007 Oct	Someya M	-
22634101	Genetic variation in DNA repair gene XRCC7 (G6721T) and susceptibility to breast cancer.	Gene	2012 Aug 15	Nasiri M	doi: 10.1016/j.gene.2012.04.065
20219974	Interaction of the double-strand break repair kinase DNA-PK and estrogen receptor-alpha.	Mol Biol Cell	2010 May 1	Medunjanin S	doi: 10.1091/mbc.E09-08-0724
23603433	Instability at the FRA8I common fragile site disrupts the genomic integrity of the KIAA0146, CEBPD and PRKDC genes in colorectal cancer.	Cancer Lett	2013 Aug 9	Brueckner LM	doi: 10.1016/j.canlet.2013.04.007
18422577	Genetic variants of the XRCC7 gene involved in DNA repair and risk of human bladder cancer.	Int J Urol	2008 Jun	Wang SY	doi: 10.1111/j.1442-2042.2008.02049.x
18644989	Targeting of AKT1 enhances radiation toxicity of human tumor cells by inhibiting DNA-PKcs-dependent DNA double-strand break repair.	Mol Cancer Ther	2008 Jul	Toulany M	doi: 10.1158/1535-7163.MCT-07-2200.
18508926	DNA-ligase IV and DNA-protein kinase play a critical role in deficient caspases activation in apoptosis-resistant cancer cells by using doxorubicin.	Mol Biol Cell	2008 Aug	Friesen C	doi: 10.1091/mbc.E08-03-0306
20590474	Polymorphic variants of DNA repair gene XRCC3 and XRCC7 and risk of prostate cancer: a study from North Indian population.	DNA Cell Biol	2010 Nov	Mandal RK	doi: 10.1089/dna.2010.1047
23098447	Association between XRCC5, 6 and 7 gene polymorphisms and the risk of breast cancer: a HuGE review and meta-analysis.	Asian Pac J Cancer Prev	2012	Zhou LP	-
21559021	The association of DNA-dependent protein kinase activity of peripheral blood lymphocytes with prognosis of cancer.	Br J Cancer	2011 May 24	Someya M	doi: 10.1038/bjc.2011.158
27988337	micorRNA-101 silences DNA-PKcs and sensitizes pancreatic cancer cells to gemcitabine.	Biochem Biophys Res Commun	2017 Jan 29	Hu H	doi: 10.1016/j.bbrc.2016.12.074
27693638	DNA-PKcs, a novel functional target of acriflavine, mediates acriflavine's p53-dependent synergistic anti-tumor efficiency with melphalan.	Cancer Lett	2016 Dec 1	Cao J	doi: 10.1016/j.canlet.2016.09.029
28399576	Local tumor control and DNA-PK activity of peripheral blood lymphocytes in prostate cancer patients receiving radiotherapy.	J Radiat Res	2017 Mar 1	Someya M	doi: 10.1093/jrr/rrw099.
28450160	A novel histone deacetylase inhibitor TMU-35435 enhances etoposide cytotoxicity through the proteasomal degradation of DNA-PKcs in triple-negative breast cancer.	Cancer Lett	2017 Aug 1	Wu YH	doi: 10.1016/j.canlet.2017.04.023
29150048	DNA-dependent protein kinase modulates the anti-cancer properties of silver nanoparticles in human cancer cells.	Mutat Res	2017 Dec	Lim HK	doi: 10.1016/j.mrgentox.2017.10.001
28498431	PRKDC regulates chemosensitivity and is a potential prognostic and predictive marker of response to adjuvant chemotherapy in breast cancer patients.	Oncol Rep	2017 Jun	Sun G	doi: 10.3892/or.2017.5634
28970727	Aberrant DNA-PKcs and ERGIC1 expression may be involved in initiation of gastric cancer.	World J Gastroenterol	2017 Sep 7	Wang FR	doi: 10.3748/wjg.v23.i33.6119.
29084207	Upregulation of the ALDOA/DNA-PK/p53 pathway by dietary restriction suppresses tumor growth.	Oncogene	2018 Feb 22	Ma D	doi: 10.1038/onc.2017.398

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
ACC	chr8	47776843	Splice_Site	novel	X4061_splice	0.7
ACC	chr8	47877764	Nonsense_Mutation	novel	E1775*	0.48
BLCA	chr8	47807203	Silent	novel	I3227I	0.44
BLCA	chr8	47864685	Silent	NA	F1814F	0.2
BLCA	chr8	47890329	Missense_Mutation	novel	S1333R	0.2
BLCA	chr8	47913952	Silent	rs575267352	F910F	0.24
BLCA	chr8	47890458	Silent	NA	L1290L	0.29
BLCA	chr8	47777835	Missense_Mutation	rs775955634	R3965C	0.16
BLCA	chr8	47834296	Silent	novel	R2684R	0.33
BLCA	chr8	47893242	Silent	rs200729621	F1248F	0.16
BLCA	chr8	47837241	Missense_Mutation	NA	E2578K	0.25
BLCA	chr8	47897274	Nonsense_Mutation	novel	S1162*	0.08
BLCA	chr8	47953712	Missense_Mutation	novel	S210L	0.48
BLCA	chr8	47799370	Silent	NA	Q3379Q	0.38
BLCA	chr8	47889134	Missense_Mutation	NA	G1387V	0.26
BLCA	chr8	47828168	Splice_Region	NA	Q2859Q	0.59
BLCA	chr8	47826795	Missense_Mutation	NA	A2882T	0.27
BLCA	chr8	47836412	Missense_Mutation	novel	S2626L	0.22
BLCA	chr8	47858581	Missense_Mutation	novel	G2134R	0.44
BLCA	chr8	47927268	Missense_Mutation	novel	R782K	0.17
BLCA	chr8	47826750	Missense_Mutation	novel	L2897V	0.31
BLCA	chr8	47803482	Splice_Site	novel	X3250_splice	0.26
BLCA	chr8	47777796	Missense_Mutation	NA	G3978S	0.1
BLCA	chr8	47859646	Missense_Mutation	NA	D2058N	0.12
BLCA	chr8	47828288	Silent	novel	E2819E	0.32
BLCA	chr8	47782203	Silent	NA	L3816L	0.12
BLCA	chr8	47778459	Splice_Region	novel	Q3951Q	0.52
BLCA	chr8	47819429	Missense_Mutation	novel	E3140K	0.16
BLCA	chr8	47807286	Missense_Mutation	NA	L3200V	0.17
BLCA	chr8	47902711	Missense_Mutation	NA	Q1043E	0.1
BLCA	chr8	47881986	Missense_Mutation	novel	D1630N	0.52
BLCA	chr8	47858575	Missense_Mutation	novel	P2136S	0.45
BLCA	chr8	47807164	Missense_Mutation	rs753361989	M3240I	0.14
BLCA	chr8	47935830	Missense_Mutation	novel	S450I	0.11
BLCA	chr8	47819432	Nonsense_Mutation	novel	Q3139*	0.12
BLCA	chr8	47831912	Missense_Mutation	rs371797273	T2723P	0.15
BLCA	chr8	47849297	Missense_Mutation	NA	M2379I	0.09
BLCA	chr8	47953655	Nonsense_Mutation	novel	S229*	0.39
BLCA	chr8	47889217	Silent	novel	L1359L	0.41
BLCA	chr8	47953639	Missense_Mutation	novel	F234L	0.29
BLCA	chr8	47904960	Missense_Mutation	NA	Y984C	0.44
BRCA	chr8	47888615	Missense_Mutation	novel	P1439L	0.2
BRCA	chr8	47800977	Missense_Mutation	NA	N3311S	0.29
BRCA	chr8	47817549	Missense_Mutation	NA	S3153C	0.33
BRCA	chr8	47913976	Missense_Mutation	NA	K902N	0.2
BRCA	chr8	47877809	Nonsense_Mutation	novel	E1760*	0.08
BRCA	chr8	47936494	Missense_Mutation	novel	K379N	0.65
BRCA	chr8	47852775	Missense_Mutation	NA	Q2301H	0.36
BRCA	chr8	47893326	Silent	novel	L1220L	0.37
BRCA	chr8	47930709	Missense_Mutation	novel	D619H	0.14
BRCA	chr8	47864732	Nonsense_Mutation	novel	E1799*	0.04
BRCA	chr8	47935042	Silent	novel	I488I	0.09
BRCA	chr8	47782215	Silent	NA	L3812L	0.33
BRCA	chr8	47785293	Frame_Shift_Ins	NA	*H3643Tfs8**	0.3
BRCA	chr8	47830694	Missense_Mutation	rs764298664	V2770I	0.34
BRCA	chr8	47927205	Nonsense_Mutation	NA	S803*	0.53
BRCA	chr8	47778629	Missense_Mutation	NA	E3895K	0.15
BRCA	chr8	47943253	Missense_Mutation	novel	L308V	0.05
BRCA	chr8	47930715	Missense_Mutation	NA	P617T	0.22
BRCA	chr8	47849433	Missense_Mutation	NA	K2359T	0.57
BRCA	chr8	47939617	Silent	rs762669277	I349I	0.41
BRCA	chr8	47798306	Silent	novel	L3463L	0.08
BRCA	chr8	47900462	Missense_Mutation	novel	E1092A	0.11
BRCA	chr8	47887582	Nonsense_Mutation	novel	G1513*	0.11
BRCA	chr8	47957407	Missense_Mutation	NA	S60Y	0.35
BRCA	chr8	47898523	Silent	NA	I1137I	0.32
BRCA	chr8	47893328	Missense_Mutation	novel	L1220V	0.18
BRCA	chr8	47934084	Missense_Mutation	novel	E502K	0.23
BRCA	chr8	47904922	Missense_Mutation	novel	N997Y	0.05
BRCA	chr8	47794349	Silent	rs765260421	S3537S	0.06
BRCA	chr8	47912551	Splice_Site	novel	X928_splice	0.37
BRCA	chr8	47927820	Missense_Mutation	NA	P737L	0.7
BRCA	chr8	47863404	Missense_Mutation	novel	L1915F	0.21
BRCA	chr8	47858614	Missense_Mutation	NA	P2123S	0.13
BRCA	chr8	47879620	Silent	NA	L1702L	0.18
BRCA	chr8	47898540	Missense_Mutation	NA	D1132N	0.34
BRCA	chr8	47789201	Missense_Mutation	NA	D3570Y	0.14
BRCA	chr8	47823971	Missense_Mutation	NA	D2937N	0.21
BRCA	chr8	47837408	Missense_Mutation	rs773817275	R2522Q	0.31
BRCA	chr8	47840087	Silent	rs761453930	F2461F	0.16
BRCA	chr8	47898482	Missense_Mutation	NA	R1151Q	0.2
BRCA	chr8	47912449	Silent	NA	T965T	0.04
BRCA	chr8	47929112	Missense_Mutation	novel	F707I	0.08
BRCA	chr8	47927333	Silent	NA	L760L	0.33
BRCA	chr8	47888571	Missense_Mutation	NA	A1454S	0.19
BRCA	chr8	47879498	Missense_Mutation	NA	M1743K	0.46
BRCA	chr8	47927307	Missense_Mutation	NA	G769D	0.2
BRCA	chr8	47863497	Silent	novel	L1884L	0.1
CESC	chr8	47788994	Frame_Shift_Del	NA	*N3605Tfs48**	0.13
CESC	chr8	47877752	Nonsense_Mutation	novel	Q1779*	0.35
CESC	chr8	47854153	Missense_Mutation	rs765893792	Q2275E	0.43
CESC	chr8	47918373	Missense_Mutation	novel	K810N	0.7
CESC	chr8	47819438	Missense_Mutation	novel	E3137K	0.38
CESC	chr8	47864685	Silent	NA	F1814F	0.23
CESC	chr8	47879535	Missense_Mutation	novel	P1731S	0.18
CESC	chr8	47849255	Missense_Mutation	NA	L2393F	0.1
CESC	chr8	47918345	Missense_Mutation	novel	R820G	0.3
CESC	chr8	47820914	Silent	novel	S3047S	0.31
CESC	chr8	47918345	Missense_Mutation	NA	R820W	0.15
CESC	chr8	47782407	Silent	NA	R3789R	0.26
CESC	chr8	47879628	Missense_Mutation	NA	T1700A	0.5
CESC	chr8	47862542	Splice_Site	NA	X1917_splice	0.39
CESC	chr8	47889039	Silent	novel	L1419L	0.51
CESC	chr8	47828348	Splice_Site	NA	X2800_splice	0.27
CESC	chr8	47789204	Missense_Mutation	NA	Q3569E	0.2
CESC	chr8	47882041	Missense_Mutation	NA	Q1611H	0.17
CESC	chr8	47782586	Missense_Mutation	novel	A3730T	0.13
CESC	chr8	47798346	Missense_Mutation	novel	M3450T	0.38
CESC	chr8	47799334	Silent	rs368284467	A3391A	0.41
CESC	chr8	47831889	Silent	novel	R2730R	0.45
CESC	chr8	47862450	Missense_Mutation	NA	A1948T	0.38
CESC	chr8	47888552	Missense_Mutation	novel	R1460K	0.3
CESC	chr8	47902694	Missense_Mutation	novel	Q1048H	0.52
CESC	chr8	47817516	Missense_Mutation	novel	W3164L	0.25
CESC	chr8	47927887	Missense_Mutation	novel	A715S	0.21
CESC	chr8	47778600	Frame_Shift_Del	novel	*F3904Lfs7**	0.26
CESC	chr8	47774315	Missense_Mutation	novel	R4082P	0.28
CESC	chr8	47823869	Nonsense_Mutation	novel	Q2971*	0.34
CESC	chr8	47852785	Splice_Site	NA	X2298_splice	0.27
CESC	chr8	47943217	Missense_Mutation	NA	L320V	0.13
CESC	chr8	47849438	Missense_Mutation	novel	E2357D	0.4
CESC	chr8	47774239	Silent	NA	L4107L	0.3
CESC	chr8	47863490	Missense_Mutation	novel	D1887H	0.19
CESC	chr8	47789204	Missense_Mutation	NA	Q3569E	0.16
CESC	chr8	47882059	Silent	NA	F1605F	0.4
CESC	chr8	47929962	Nonsense_Mutation	novel	S648*	0.56
CESC	chr8	47957184	Missense_Mutation	novel	S104C	0.24
CESC	chr8	47912515	Silent	novel	G943G	0.24
CESC	chr8	47839233	Missense_Mutation	NA	E2490K	0.49
CESC	chr8	47927303	Silent	NA	L770L	0.38
CHOL	chr8	47798235	Splice_Site	novel	X3486_splice	0.12
CHOL	chr8	47929979	Frame_Shift_Del	novel	*F642Lfs12**	0.43
COAD	chr8	47785174	Frame_Shift_Del	NA	*K3681Nfs6**	0.32
COAD	chr8	47930009	Silent	rs774814292	E632E	0.15
COAD	chr8	47859660	Nonsense_Mutation	NA	S2053*	0.3
COAD	chr8	47889049	Silent	rs750460161	L1415L	0.35
COAD	chr8	47783773	Missense_Mutation	NA	Y3715C	0.26
COAD	chr8	47877819	Silent	NA	P1756P	0.14
COAD	chr8	47886051	Frame_Shift_Del	NA	*E1557Sfs16**	0.16
COAD	chr8	47936516	Missense_Mutation	rs778630373	P372L	0.24
COAD	chr8	47849471	Silent	rs754824486	A2346A	0.35
COAD	chr8	47881957	Silent	rs529999429	L1639L	0.29
COAD	chr8	47898471	Nonsense_Mutation	NA	R1155*	0.31
COAD	chr8	47934089	Missense_Mutation	novel	G500D	0.29
COAD	chr8	47935769	Silent	novel	A470A	0.35
COAD	chr8	47953825	Silent	novel	L201L	0.12
COAD	chr8	47953826	Missense_Mutation	NA	L201P	0.12
COAD	chr8	47860967	Missense_Mutation	NA	P1997H	0.05
COAD	chr8	47933113	Missense_Mutation	NA	N561K	0.08
COAD	chr8	47777761	Silent	NA	R3989R	0.17
COAD	chr8	47849471	Silent	rs754824486	A2346A	0.21
COAD	chr8	47862451	Silent	rs546063249	C1947C	0.24
COAD	chr8	47889021	Missense_Mutation	novel	A1425T	0.08
COAD	chr8	47774288	Missense_Mutation	NA	A4091V	0.12
COAD	chr8	47782246	Nonsense_Mutation	NA	L3802*	0.37
COAD	chr8	47877823	Missense_Mutation	NA	S1755N	0.2
COAD	chr8	47957245	Nonsense_Mutation	NA	E84*	0.22
COAD	chr8	47777724	Missense_Mutation	novel	M4002L	0.26
COAD	chr8	47898510	Missense_Mutation	novel	H1142N	0.1
COAD	chr8	47927786	Silent	rs534226541	Y748Y	0.16
COAD	chr8	47862101	Silent	NA	I1982I	0.23
COAD	chr8	47782241	Missense_Mutation	NA	E3804K	0.41
COAD	chr8	47849377	Splice_Site	NA	X2377_splice	0.32
COAD	chr8	47885945	Missense_Mutation	NA	M1592T	0.21
COAD	chr8	47820918	Missense_Mutation	rs373925433	R3046H	0.47
COAD	chr8	47794292	Splice_Region	novel	A3556A	0.04
COAD	chr8	47826713	Missense_Mutation	novel	R2909Q	0.17
COAD	chr8	47893179	Silent	NA	T1269T	0.56
COAD	chr8	47776910	Missense_Mutation	novel	Y4039C	0.46
COAD	chr8	47834238	Frame_Shift_Del	NA	*R2704Gfs13**	0.42
COAD	chr8	47774122	3'UTR	novel		0.07
COAD	chr8	47929851	Splice_Site	NA	X684_splice	0.21
COAD	chr8	47840161	Frame_Shift_Ins	NA	*D2437Wfs3**	0.11
COAD	chr8	47777770	Silent	rs56405602	H3986H	0.35
COAD	chr8	47823962	Missense_Mutation	rs756866332	R2940C	0.34
COAD	chr8	47954350	Frame_Shift_Del	novel	*K165Nfs11**	0.12
COAD	chr8	47854080	Splice_Region	NA		0.35
COAD	chr8	47799257	Missense_Mutation	NA	A3417V	0.3
COAD	chr8	47826834	Silent	NA	L2869L	0.44
COAD	chr8	47834323	Silent	NA	S2675S	0.48
COAD	chr8	47779047	Frame_Shift_Del	novel	*M3846Cfs12**	0.13
COAD	chr8	47794349	Silent	rs765260421	S3537S	0.4
COAD	chr8	47893306	Frame_Shift_Del	NA	*G1227Vfs50**	0.25
COAD	chr8	47803426	Frame_Shift_Del	NA	*T3268Pfs7**	0.5
COAD	chr8	47799302	Frame_Shift_Ins	novel	*S3402Ifs16**	0.04
COAD	chr8	47799304	Frame_Shift_Ins	novel	*W3401Cfs4**	0.01
COAD	chr8	47849235	Missense_Mutation	NA	V2400A	0.12
COAD	chr8	47778796	Silent	rs202104334	G3861G	0.3
COAD	chr8	47794379	Missense_Mutation	NA	Q3527H	0.24
COAD	chr8	47794364	Silent	NA	P3532P	0.21
COAD	chr8	47934007	Silent	rs551598588	Y527Y	0.06
COAD	chr8	47893306	Frame_Shift_Del	NA	*G1227Vfs50**	0.38
COAD	chr8	47953712	Missense_Mutation	novel	S210L	0.12
COAD	chr8	47785212	Frame_Shift_Del	NA	M3670*	0.5
COAD	chr8	47788993	Frame_Shift_Ins	NA	*N3605Kfs3**	0.22
COAD	chr8	47794428	Missense_Mutation	NA	A3511V	0.57
COAD	chr8	47862422	Missense_Mutation	NA	N1957S	0.19
COAD	chr8	47803474	Missense_Mutation	novel	F3252V	0.15
COAD	chr8	47828289	Missense_Mutation	novel	E2819V	0.17
COAD	chr8	47934055	Silent	novel	S511S	0.23
COAD	chr8	47774265	Frame_Shift_Del	NA	*S4099Qfs6**	0.25
COAD	chr8	47831893	Missense_Mutation	NA	R2729H	0.36
COAD	chr8	47836433	Missense_Mutation	rs138740003	R2619H	0.29
COAD	chr8	47854116	Missense_Mutation	NA	P2287L	0.23
COAD	chr8	47820828	Missense_Mutation	rs370147042	A3076V	0.21
COAD	chr8	47837408	Missense_Mutation	rs773817275	R2522Q	0.3
COAD	chr8	47862517	Missense_Mutation	NA	E1925D	0.25
COAD	chr8	47912432	Missense_Mutation	rs528650708	R971Q	0.32
COAD	chr8	47915390	Missense_Mutation	novel	R852I	0.41
COAD	chr8	47776916	Frame_Shift_Del	NA	*N4037Ifs15**	0.17
COAD	chr8	47803459	Nonsense_Mutation	NA	K3257*	0.28
COAD	chr8	47834238	Frame_Shift_Del	NA	*R2704Gfs13**	0.26
COAD	chr8	47782577	Nonsense_Mutation	NA	R3733*	0.22
COAD	chr8	47837408	Missense_Mutation	rs773817275	R2522Q	0.28
COAD	chr8	47776968	Frame_Shift_Del	NA	*M4020Cfs2**	0.31
COAD	chr8	47881513	Nonsense_Mutation	NA	S1657*	0.22
COAD	chr8	47929879	Missense_Mutation	NA	N676H	0.18
COAD	chr8	47862090	Missense_Mutation	rs199898990	R1986H	0.43
COAD	chr8	47776881	Nonsense_Mutation	NA	R4049*	0.23
COAD	chr8	47836491	Missense_Mutation	novel	T2600A	0.2
COAD	chr8	47862531	Missense_Mutation	rs373832970	D1921N	0.15
ESCA	chr8	47893306	Frame_Shift_Del	NA	*G1227Vfs50**	0.24
ESCA	chr8	47863537	Missense_Mutation	novel	M1871T	0.18
ESCA	chr8	47782409	Missense_Mutation	novel	R3789G	0.11
ESCA	chr8	47953655	Nonsense_Mutation	novel	S229*	0.19
ESCA	chr8	47954438	Silent	novel	Q136Q	0.38
ESCA	chr8	47826769	Missense_Mutation	novel	I2890M	0.38
ESCA	chr8	47782256	Splice_Site	novel	X3799_splice	0.23
ESCA	chr8	47831835	Silent	novel	V2748V	0.56
ESCA	chr8	47820876	Missense_Mutation	novel	S3060F	0.27
ESCA	chr8	47778600	Silent	rs765475039	F3904F	0.14
ESCA	chr8	47821793	Splice_Site	novel	X2975_splice	0.26
ESCA	chr8	47839171	Frame_Shift_Ins	novel	*L2510Ffs4**	0.27
ESCA	chr8	47915332	Silent	novel	L871L	0.05
ESCA	chr8	47821710	Missense_Mutation	novel	Y3002C	0.43
GBM	chr8	47782435	Missense_Mutation	novel	A3780V	0.41
GBM	chr8	47830667	Missense_Mutation	novel	D2779Y	0.48
GBM	chr8	47839227	Missense_Mutation	novel	D2492Y	0.26
GBM	chr8	47774200	Silent	novel	T4120T	0.25
GBM	chr8	47936364	Missense_Mutation	novel	Y423N	0.08
GBM	chr8	47953657	Silent	novel	S228S	0.12
GBM	chr8	47782190	Missense_Mutation	novel	S3821P	0.09
GBM	chr8	47828221	Missense_Mutation	novel	R2842C	0.4
GBM	chr8	47849174	Silent	rs764299256	F2420F	0.11
GBM	chr8	47934017	Missense_Mutation	novel	Y524C	0.14
GBM	chr8	47957248	Nonsense_Mutation	novel	E83*	0.42
GBM	chr8	47799292	Silent	novel	P3405P	0.11
GBM	chr8	47893318	Missense_Mutation	NA	T1223I	0.23
GBM	chr8	47788938	Missense_Mutation	novel	G3624C	0.32
GBM	chr8	47859694	Nonsense_Mutation	NA	Q2042*	0.23
HNSC	chr8	47785122	Nonsense_Mutation	novel	E3700*	0.4
HNSC	chr8	47834307	Missense_Mutation	novel	A2681T	0.21
HNSC	chr8	47823992	Missense_Mutation	novel	Y2930H	0.09
HNSC	chr8	47902751	Silent	novel	C1029C	0.06
HNSC	chr8	47785243	Silent	novel	F3659F	0.15
HNSC	chr8	47929978	Nonsense_Mutation	novel	E643*	0.06
HNSC	chr8	47886031	Missense_Mutation	novel	F1563L	0.11
HNSC	chr8	47886112	Silent	rs371799969	A1536A	0.43
HNSC	chr8	47914058	Missense_Mutation	novel	S875F	0.36
HNSC	chr8	47955938	Missense_Mutation	novel	T112I	0.1
HNSC	chr8	47785252	Silent	novel	L3656L	0.27
HNSC	chr8	47933049	Missense_Mutation	novel	L583V	0.22
HNSC	chr8	47849160	Missense_Mutation	novel	R2425T	0.23
HNSC	chr8	47794403	Missense_Mutation	novel	E3519D	0.09
HNSC	chr8	47889088	Silent	novel	L1402L	0.09
HNSC	chr8	47939574	Missense_Mutation	rs373460300	R364C	0.25
HNSC	chr8	47893258	Missense_Mutation	novel	Y1243F	0.5
HNSC	chr8	47893253	Missense_Mutation	rs200017529	R1245W	0.5
HNSC	chr8	47897238	Missense_Mutation	novel	A1174G	0.55
HNSC	chr8	47943334	Missense_Mutation	NA	Q281E	0.09
HNSC	chr8	47834210	Missense_Mutation	novel	D2713G	0.32
HNSC	chr8	47893253	Missense_Mutation	rs200017529	R1245W	0.22
HNSC	chr8	47807299	Missense_Mutation	novel	E3195D	0.27
HNSC	chr8	47882084	Missense_Mutation	novel	L1597S	0.34
HNSC	chr8	47927195	Splice_Region	novel	S806S	0.38
HNSC	chr8	47800841	Silent	novel	A3356A	0.48
HNSC	chr8	47849423	Silent	novel	V2362V	0.18
HNSC	chr8	47863441	Missense_Mutation	novel	S1903L	0.2
HNSC	chr8	47820778	Nonsense_Mutation	novel	Q3093*	0.25
HNSC	chr8	47776848	Missense_Mutation	novel	T4060S	0.14
HNSC	chr8	47794348	Missense_Mutation	novel	E3538K	0.27
HNSC	chr8	47929999	Missense_Mutation	novel	E636Q	0.08
HNSC	chr8	47803370	Silent	rs750682248	C3286C	0.28
KIRC	chr8	47898561	Nonsense_Mutation	novel	Q1125*	0.26
KIRC	chr8	47882036	Missense_Mutation	rs767235558	H1613R	0.36
KIRC	chr8	47782237	Nonsense_Mutation	NA	W3805*	0.15
KIRC	chr8	47854116	Missense_Mutation	novel	P2287R	0.2
KIRC	chr8	47779093	Frame_Shift_Ins	novel	*S3830Rfs18**	0.04
KIRC	chr8	47779095	Splice_Site	novel	X3830_splice	0.02
KIRC	chr8	47817549	Missense_Mutation	NA	S3153Y	0.28
KIRC	chr8	47927808	Missense_Mutation	novel	I741T	0.41
KIRC	chr8	47855252	Missense_Mutation	NA	C2244Y	0.32
KIRP	chr8	47955879	Missense_Mutation	novel	I132F	0.38
KIRP	chr8	47831862	Silent	NA	L2739L	0.4
KIRP	chr8	47902693	Nonsense_Mutation	novel	Q1049*	0.09
KIRP	chr8	47913945	Nonsense_Mutation	NA	R913*	0.31
KIRP	chr8	47800844	Silent	novel	K3355K	0.4
KIRP	chr8	47858895	Missense_Mutation	novel	L2100R	0.34
KIRP	chr8	47897254	Missense_Mutation	NA	V1169L	0.4
KIRP	chr8	47930672	Nonsense_Mutation	novel	C630_R631delins*	0.47
KIRP	chr8	47902748	Silent	novel	G1030G	0.17
LAML	chr8	47777876	Splice_Site	rs760681934	X3952_splice	0.2
LGG	chr8	47794354	Missense_Mutation	NA	S3536G	0.4
LGG	chr8	47879643	Missense_Mutation	NA	L1695V	0.14
LGG	chr8	47939681	Missense_Mutation	rs769059077	A328V	0.17
LGG	chr8	47837272	Silent	novel	S2567S	0.35
LGG	chr8	47849292	Missense_Mutation	novel	A2381V	0.29
LGG	chr8	47854156	Missense_Mutation	novel	I2274V	0.32
LGG	chr8	47858900	Silent	rs544510562	T2098T	0.49
LGG	chr8	47913936	Nonsense_Mutation	novel	E916*	0.1
LGG	chr8	47831880	Missense_Mutation	NA	M2733I	0.14
LGG	chr8	47877757	Nonsense_Mutation	novel	L1777*	0.04
LIHC	chr8	47831893	Missense_Mutation	novel	R2729L	0.19
LIHC	chr8	47877779	Nonsense_Mutation	novel	Q1770*	0.09
LIHC	chr8	47943852	Splice_Site	NA	X270_splice	0.3
LIHC	chr8	47882095	Splice_Region	NA	V1593V	0.17
LIHC	chr8	47927239	Missense_Mutation	NA	I792V	0.44
LIHC	chr8	47803423	Silent	NA	R3269R	0.14
LIHC	chr8	47881499	Missense_Mutation	NA	N1662D	0.42
LIHC	chr8	47943287	Silent	novel	V296V	0.13
LIHC	chr8	47882076	Missense_Mutation	NA	M1600V	0.33
LIHC	chr8	47927808	Missense_Mutation	novel	I741T	0.23
LIHC	chr8	47927337	Missense_Mutation	NA	G759D	0.24
LIHC	chr8	47789012	Missense_Mutation	NA	T3599I	0.72
LIHC	chr8	47902618	Nonsense_Mutation	NA	K1074*	0.49
LIHC	chr8	47863466	Missense_Mutation	novel	K1895E	0.1
LIHC	chr8	47934091	Splice_Site	novel	X500_splice	0.72
LIHC	chr8	47782504	Missense_Mutation	NA	D3757V	0.26
LIHC	chr8	47834398	Splice_Site	novel	X2651_splice	0.28
LIHC	chr8	47879600	Frame_Shift_Del	novel	*G1704Dfs35**	0.24
LIHC	chr8	47819508	Splice_Region	NA	N3113N	0.22
LIHC	chr8	47785245	Missense_Mutation	NA	F3659V	0.45
LIHC	chr8	47935734	Missense_Mutation	novel	V482E	0.51
LIHC	chr8	47890322	In_Frame_Ins	novel	C1335dup	0.57
LIHC	chr8	47930761	Missense_Mutation	novel	W601C	0.33
LIHC	chr8	47862128	Splice_Site	novel	X1974_splice	0.11
LIHC	chr8	47855374	Splice_Site	novel	X2204_splice	0.44
LIHC	chr8	47789174	Missense_Mutation	NA	S3579P	0.14
LUAD	chr8	47859675	Missense_Mutation	NA	G2048E	0.31
LUAD	chr8	47858903	Silent	rs562591745	L2097L	0.61
LUAD	chr8	47803391	Missense_Mutation	novel	S3279R	0.09
LUAD	chr8	47857214	Missense_Mutation	novel	Y2184C	0.2
LUAD	chr8	47820894	Missense_Mutation	NA	Q3054P	0.3
LUAD	chr8	47830685	Missense_Mutation	rs182343050	R2773G	0.12
LUAD	chr8	47799282	Missense_Mutation	novel	V3409L	0.07
LUAD	chr8	47834217	Missense_Mutation	rs746188479	E2711K	0.1
LUAD	chr8	47889030	Missense_Mutation	novel	K1422E	0.15
LUAD	chr8	47927272	Missense_Mutation	novel	D781Y	0.08
LUAD	chr8	47799283	Silent	NA	G3408G	0.59
LUAD	chr8	47834390	Missense_Mutation	NA	R2653T	0.05
LUAD	chr8	47859698	Missense_Mutation	NA	M2040I	0.06
LUAD	chr8	47836416	Missense_Mutation	novel	L2625F	0.35
LUAD	chr8	47800886	Silent	novel	L3341L	0.2
LUAD	chr8	47933108	Nonsense_Mutation	novel	L563*	0.53
LUAD	chr8	47831872	Missense_Mutation	NA	Q2736R	0.11
LUAD	chr8	47862519	Nonsense_Mutation	novel	E1925*	0.32
LUAD	chr8	47864695	Missense_Mutation	novel	R1811L	0.13
LUAD	chr8	47789234	Frame_Shift_Ins	novel	*K3559Qfs13**	0.07
LUAD	chr8	47904976	Missense_Mutation	novel	V979L	0.1
LUAD	chr8	47897279	Frame_Shift_Del	novel	*A1161Hfs13**	0.06
LUAD	chr8	47817463	Missense_Mutation	novel	I3182V	0.11
LUAD	chr8	47776918	Missense_Mutation	NA	K4036N	0.46
LUAD	chr8	47849255	Missense_Mutation	NA	L2393F	0.07
LUAD	chr8	47877750	Missense_Mutation	novel	Q1779H	0.14
LUAD	chr8	47953705	Silent	novel	V212V	0.13
LUAD	chr8	47799225	Nonsense_Mutation	novel	E3428*	0.56
LUAD	chr8	47799226	Missense_Mutation	novel	E3427D	0.55
LUAD	chr8	47864607	Silent	NA	F1840F	0.23
LUAD	chr8	47913976	Missense_Mutation	NA	K902N	0.28
LUAD	chr8	47849486	Silent	NA	L2341L	0.09
LUAD	chr8	47858916	Missense_Mutation	novel	C2093S	0.08
LUAD	chr8	47877761	Missense_Mutation	NA	E1776K	0.07
LUAD	chr8	47830703	Missense_Mutation	novel	A2767S	0.86
LUAD	chr8	47893156	Missense_Mutation	NA	G1277A	0.16
LUAD	chr8	47834397	Splice_Site	novel	X2651_splice	0.11
LUAD	chr8	47862517	Missense_Mutation	NA	E1925D	0.53
LUAD	chr8	47914050	Nonsense_Mutation	novel	E878*	0.33
LUAD	chr8	47855341	Silent	NA	R2214R	0.4
LUAD	chr8	47913936	Missense_Mutation	novel	E916Q	0.21
LUAD	chr8	47789238	Missense_Mutation	NA	R3557S	0.34
LUAD	chr8	47807301	Missense_Mutation	NA	E3195K	0.34
LUAD	chr8	47935887	Missense_Mutation	novel	Y431F	0.08
LUAD	chr8	47953660	Missense_Mutation	NA	L227F	0.35
LUAD	chr8	47889152	Missense_Mutation	NA	S1381I	0.33
LUAD	chr8	47886029	Nonsense_Mutation	novel	S1564*	0.35
LUAD	chr8	47957406	Frame_Shift_Ins	novel	*R61Tfs27**	0.2
LUAD	chr8	47893251	Silent	novel	R1245R	0.63
LUAD	chr8	47776984	Splice_Site	NA	X4015_splice	0.3
LUAD	chr8	47933099	Missense_Mutation	novel	D566G	0.33
LUAD	chr8	47776896	Missense_Mutation	novel	I4044L	0.09
LUAD	chr8	47830728	Missense_Mutation	rs148855050	K2758N	0.13
LUSC	chr8	47849456	Silent	novel	Q2351Q	0.33
LUSC	chr8	47800919	Missense_Mutation	novel	L3330F	0.13
LUSC	chr8	47807327	Splice_Site	NA	X3186_splice	0.34
LUSC	chr8	47783785	Missense_Mutation	novel	P3711L	0.48
LUSC	chr8	47881976	Missense_Mutation	NA	W1633L	0.19
LUSC	chr8	47849400	Missense_Mutation	novel	S2370T	0.19
LUSC	chr8	47779054	Silent	novel	L3843L	0.18
LUSC	chr8	47803345	Missense_Mutation	novel	E3295Q	0.19
LUSC	chr8	47864588	Missense_Mutation	novel	A1847P	0.5
LUSC	chr8	47927272	Missense_Mutation	novel	D781H	0.44
LUSC	chr8	47798386	Missense_Mutation	novel	A3437S	0.22
LUSC	chr8	47807243	Missense_Mutation	NA	P3214H	0.31
LUSC	chr8	47823920	Missense_Mutation	novel	Q2954E	0.08
LUSC	chr8	47798315	Missense_Mutation	novel	E3460D	0.13
LUSC	chr8	47902571	Missense_Mutation	NA	F1089L	0.19
LUSC	chr8	47798322	Nonsense_Mutation	novel	S3458*	0.17
LUSC	chr8	47957237	Silent	NA	L86L	0.81
LUSC	chr8	47834324	Missense_Mutation	rs369642176	S2675F	0.29
LUSC	chr8	47803479	Missense_Mutation	novel	N3250S	0.24
LUSC	chr8	47826676	Silent	novel	L2921L	0.26
LUSC	chr8	47794406	Silent	novel	V3518V	0.13
LUSC	chr8	47953645	Missense_Mutation	novel	C232W	0.14
LUSC	chr8	47849215	Nonsense_Mutation	novel	G2407*	0.35
LUSC	chr8	47830695	Silent	NA	V2769V	0.16
LUSC	chr8	47943340	Missense_Mutation	NA	A279T	0.37
LUSC	chr8	47929913	Silent	novel	S664S	0.67
LUSC	chr8	47859757	Missense_Mutation	rs541975682	G2021C	0.27
LUSC	chr8	47897284	Missense_Mutation	NA	P1159S	0.54
LUSC	chr8	47778472	Missense_Mutation	novel	G3947V	0.22
LUSC	chr8	47799212	Nonsense_Mutation	NA	S3432*	0.41
LUSC	chr8	47774315	Missense_Mutation	rs778808256	R4082Q	0.2
LUSC	chr8	47858978	Silent	novel	R2072R	0.16
LUSC	chr8	47890313	Frame_Shift_Del	novel	*V1339Sfs11**	0.27
LUSC	chr8	47877770	Missense_Mutation	novel	V1773I	0.15
LUSC	chr8	47897194	Missense_Mutation	novel	E1189Q	0.27
LUSC	chr8	47862462	Missense_Mutation	novel	A1944S	0.38
LUSC	chr8	47857282	Silent	novel	A2161A	0.49
LUSC	chr8	47794375	Missense_Mutation	NA	I3529V	0.3
LUSC	chr8	47849179	Missense_Mutation	NA	D2419Y	0.06
MESO	chr8	47831909	Missense_Mutation	novel	D2724N	0.34
OV	chr8	47927836	Missense_Mutation	novel	F732I	0.07
OV	chr8	47849408	In_Frame_Ins	novel	V2367_T2368insGISEEKVKA	0.04
OV	chr8	47834276	Missense_Mutation	novel	A2691E	0.04
OV	chr8	47929118	Missense_Mutation	novel	A705T	0.18
OV	chr8	47788981	Frame_Shift_Ins	novel	*M3609Ifs3**	0.41
OV	chr8	47912550	Frame_Shift_Del	novel	*E932Nfs48**	0.03
OV	chr8	47777811	Frame_Shift_Ins	novel	*P3973Afs40**	0.09
OV	chr8	47912525	Missense_Mutation	novel	F940Y	0.04
OV	chr8	47857244	Missense_Mutation	novel	S2174Y	0.04
OV	chr8	47893287	Silent	rs774629196	S1233S	0.36
OV	chr8	47898537	Missense_Mutation	novel	H1133D	0.33
OV	chr8	47855320	Frame_Shift_Del	novel	*K2221Nfs18**	0.7
OV	chr8	47927836	Missense_Mutation	novel	F732I	0.16
OV	chr8	47821630	Missense_Mutation	novel	K3029E	0.28
OV	chr8	47837265	Missense_Mutation	novel	P2570S	0.19
OV	chr8	47834198	Missense_Mutation	NA	K2717R	0.12
OV	chr8	47826768	Missense_Mutation	rs565638844	R2891C	0.14
OV	chr8	47858909	Silent	rs767858150	A2095A	0.46
OV	chr8	47788973	Missense_Mutation	novel	R3612I	0.04
OV	chr8	47823899	Missense_Mutation	novel	A2961T	0.03
OV	chr8	47893379	Missense_Mutation	novel	S1203P	0.14
PAAD	chr8	47831897	Silent	novel	L2728L	0.15
PAAD	chr8	47778794	Missense_Mutation	novel	A3862V	0.07
PAAD	chr8	47778795	Missense_Mutation	rs568709506	A3862T	0.08
PAAD	chr8	47789047	Splice_Region	novel	D3587D	0.19
PAAD	chr8	47830687	Missense_Mutation	novel	Y2772C	0.14
PAAD	chr8	47877806	Missense_Mutation	novel	L1761V	0.19
PAAD	chr8	47778622	Missense_Mutation	novel	F3897C	0.2
PRAD	chr8	47890364	Missense_Mutation	novel	T1322A	0.09
PRAD	chr8	47777854	Missense_Mutation	novel	L3958F	0.36
PRAD	chr8	47819414	Missense_Mutation	novel	I3145L	0.33
PRAD	chr8	47888594	Missense_Mutation	NA	S1446N	0.57
PRAD	chr8	47826708	Missense_Mutation	NA	R2911S	0.16
PRAD	chr8	47898474	Missense_Mutation	NA	P1154S	0.3
PRAD	chr8	47863512	Silent	novel	V1879V	0.33
PRAD	chr8	47778599	Missense_Mutation	rs762000221	A3905T	0.42
PRAD	chr8	47849379	Missense_Mutation	novel	R2377M	0.37
READ	chr8	47788993	Frame_Shift_Ins	NA	*N3605Kfs3**	0.6
READ	chr8	47943281	Silent	NA	L298L	0.2
READ	chr8	47927836	Missense_Mutation	NA	F732V	0.15
READ	chr8	47890363	Missense_Mutation	rs747889965	T1322K	0.18
READ	chr8	47855343	Nonsense_Mutation	NA	R2214*	0.08
READ	chr8	47888611	Silent	NA	D1440D	0.42
READ	chr8	47782210	Missense_Mutation	novel	D3814A	0.11
READ	chr8	47840087	Silent	rs761453930	F2461F	0.35
READ	chr8	47837408	Missense_Mutation	rs773817275	R2522Q	0.5
READ	chr8	47927806	Nonsense_Mutation	NA	E742*	0.54
READ	chr8	47831858	Missense_Mutation	novel	L2741V	0.11
READ	chr8	47837408	Missense_Mutation	rs773817275	R2522Q	0.19
SARC	chr8	47834222	Missense_Mutation	novel	G2709E	0.08
SARC	chr8	47889201	Frame_Shift_Ins	novel	N1365*	0.38
SARC	chr8	47933050	Silent	novel	T582T	0.18
SARC	chr8	47820835	Nonsense_Mutation	novel	Q3074*	0.25
SARC	chr8	47953897	Silent	novel	L177L	0.65
SARC	chr8	47852728	Missense_Mutation	novel	A2317G	0.26
SARC	chr8	47789009	Frame_Shift_Del	novel	*P3600Lfs2**	0.68
SARC	chr8	47826812	Frame_Shift_Del	novel	Q2864*	0.36
SARC	chr8	47889130	Missense_Mutation	novel	D1388E	0.07
SKCM	chr8	47828191	Missense_Mutation	NA	P2852S	0.35
SKCM	chr8	47785166	Missense_Mutation	novel	P3685L	0.18
SKCM	chr8	47935871	Missense_Mutation	NA	E436D	0.42
SKCM	chr8	47858862	Missense_Mutation	rs755702932	P2111L	0.37
SKCM	chr8	47831882	Missense_Mutation	novel	M2733L	0.45
SKCM	chr8	47837249	Missense_Mutation	NA	P2575L	0.38
SKCM	chr8	47943238	Missense_Mutation	rs571168592	L313F	0.54
SKCM	chr8	47943239	Silent	novel	A312A	0.53
SKCM	chr8	47881478	Missense_Mutation	NA	P1669S	0.36
SKCM	chr8	47893276	Missense_Mutation	novel	A1237V	0.23
SKCM	chr8	47890321	Missense_Mutation	novel	T1336I	0.38
SKCM	chr8	47785192	Silent	novel	P3676P	0.28
SKCM	chr8	47902630	Missense_Mutation	NA	P1070S	0.43
SKCM	chr8	47777745	Missense_Mutation	NA	P3995S	0.37
SKCM	chr8	47794488	Missense_Mutation	NA	P3491L	0.39
SKCM	chr8	47834317	Silent	novel	S2677S	0.4
SKCM	chr8	47849174	Silent	rs764299256	F2420F	0.27
SKCM	chr8	47840087	Silent	rs761453930	F2461F	0.27
SKCM	chr8	47859625	Missense_Mutation	NA	R2065C	0.26
SKCM	chr8	47936517	Missense_Mutation	NA	P372S	0.31
SKCM	chr8	47953671	Silent	NA	L224L	0.22
SKCM	chr8	47943221	Silent	NA	S318S	0.34
SKCM	chr8	47859668	Silent	NA	Q2050Q	0.23
SKCM	chr8	47863520	Silent	novel	L1877L	0.63
SKCM	chr8	47933083	Silent	rs373088662	S571S	0.17
SKCM	chr8	47877791	Missense_Mutation	rs767425926	L1766F	0.23
SKCM	chr8	47955908	Missense_Mutation	novel	K122R	0.36
SKCM	chr8	47823962	Missense_Mutation	rs756866332	R2940C	0.2
SKCM	chr8	47831913	Silent	novel	R2722R	0.32
SKCM	chr8	47927232	Missense_Mutation	novel	P794L	0.42
SKCM	chr8	47839168	Silent	rs748416748	I2511I	0.42
SKCM	chr8	47785143	Missense_Mutation	NA	E3693K	0.24
SKCM	chr8	47893326	Silent	NA	L1220L	0.09
SKCM	chr8	47800856	Silent	NA	I3351I	0.26
SKCM	chr8	47834330	Missense_Mutation	NA	P2673L	0.35
SKCM	chr8	47828323	Missense_Mutation	novel	L2808F	0.26
SKCM	chr8	47831918	Missense_Mutation	rs748936147	G2721S	0.32
SKCM	chr8	47837342	Missense_Mutation	NA	S2544F	0.14
SKCM	chr8	47788960	Silent	NA	A3616A	0.21
SKCM	chr8	47889143	Missense_Mutation	NA	F1384Y	0.59
SKCM	chr8	47927833	Missense_Mutation	novel	L733F	0.25
SKCM	chr8	47863448	Missense_Mutation	novel	H1901Y	0.51
SKCM	chr8	47778621	Silent	NA	F3897F	0.35
SKCM	chr8	47879538	Missense_Mutation	novel	P1730S	0.33
SKCM	chr8	47900442	Missense_Mutation	novel	F1099L	0.59
SKCM	chr8	47882090	Missense_Mutation	NA	A1595V	0.67
SKCM	chr8	47889217	Silent	novel	L1359L	0.53
SKCM	chr8	47957425	Missense_Mutation	NA	Q54L	0.37
SKCM	chr8	47857283	Missense_Mutation	NA	A2161G	0.48
SKCM	chr8	47778469	Missense_Mutation	NA	S3948F	0.36
SKCM	chr8	47943221	Silent	NA	S318S	0.31
SKCM	chr8	47837324	Missense_Mutation	rs373258150	I2550T	0.28
SKCM	chr8	47927234	Silent	NA	L793L	0.34
SKCM	chr8	47830695	Silent	novel	V2769V	0.3
SKCM	chr8	47785169	Missense_Mutation	novel	S3684L	0.38
SKCM	chr8	47890340	Missense_Mutation	NA	Y1330H	0.14
SKCM	chr8	47837255	Missense_Mutation	NA	P2573L	0.56
SKCM	chr8	47778600	Silent	rs765475039	F3904F	0.35
SKCM	chr8	47857291	Silent	NA	R2158R	0.33
SKCM	chr8	47893247	Missense_Mutation	NA	P1247S	0.16
STAD	chr8	47777763	Missense_Mutation	NA	R3989W	0.27
STAD	chr8	47902768	Missense_Mutation	novel	T1024A	0.09
STAD	chr8	47831888	Missense_Mutation	novel	R2731W	0.13
STAD	chr8	47889152	Missense_Mutation	novel	S1381N	0.13
STAD	chr8	47831923	Missense_Mutation	NA	A2719V	0.2
STAD	chr8	47935739	Silent	NA	S480S	0.19
STAD	chr8	47828265	Missense_Mutation	novel	S2827C	0.17
STAD	chr8	47934023	Missense_Mutation	NA	P522H	0.2
STAD	chr8	47863514	Missense_Mutation	NA	V1879M	0.27
STAD	chr8	47783764	Missense_Mutation	rs780805923	R3718Q	0.23
STAD	chr8	47788994	Frame_Shift_Del	NA	*N3605Tfs48**	0.26
STAD	chr8	47834238	Frame_Shift_Del	NA	*R2704Gfs13**	0.16
STAD	chr8	47943277	Missense_Mutation	novel	W300R	0.11
STAD	chr8	47902746	Missense_Mutation	rs773506987	R1031Q	0.29
STAD	chr8	47933058	Frame_Shift_Del	novel	*D580Ifs23**	0.5
STAD	chr8	47788994	Frame_Shift_Del	NA	*N3605Tfs48**	0.2
STAD	chr8	47939583	Missense_Mutation	NA	I361V	0.09
STAD	chr8	47828189	Silent	NA	P2852P	0.26
STAD	chr8	47849288	Silent	NA	V2382V	0.22
STAD	chr8	47830715	Frame_Shift_Del	novel	M2763*	0.38
STAD	chr8	47831922	Silent	rs750298710	A2719A	0.26
STAD	chr8	47854185	Missense_Mutation	NA	D2264V	0.25
STAD	chr8	47889129	Missense_Mutation	NA	V1389I	0.39
STAD	chr8	47936499	Missense_Mutation	NA	A378T	0.33
STAD	chr8	47830671	Silent	NA	H2777H	0.44
STAD	chr8	47834357	Missense_Mutation	NA	T2664I	0.44
STAD	chr8	47857293	Missense_Mutation	NA	R2158C	0.32
STAD	chr8	47882007	Missense_Mutation	NA	L1623M	0.29
STAD	chr8	47902650	Missense_Mutation	NA	L1063R	0.27
STAD	chr8	47778557	Missense_Mutation	novel	G3919R	0.3
STAD	chr8	47828255	Frame_Shift_Ins	NA	*N2830Kfs16**	0.26
STAD	chr8	47936475	Missense_Mutation	NA	V386I	0.08
STAD	chr8	47840013	Splice_Region	novel		0.31
STAD	chr8	47776955	Missense_Mutation	NA	G4024E	0.1
STAD	chr8	47943357	Missense_Mutation	rs775322168	R273H	0.11
STAD	chr8	47777811	In_Frame_Ins	novel	L3972_P3973insNKTYF	0.04
STAD	chr8	47788968	Missense_Mutation	NA	Y3614H	0.13
STAD	chr8	47788994	Frame_Shift_Del	NA	*N3605Tfs48**	0.2
STAD	chr8	47834244	Missense_Mutation	rs8178178	K2702E	0.13
STAD	chr8	47836497	Nonsense_Mutation	NA	R2598*	0.29
STAD	chr8	47897279	Silent	NA	S1160S	0.19
STAD	chr8	47933082	Missense_Mutation	NA	V572I	0.18
STAD	chr8	47939568	Missense_Mutation	NA	Y366H	0.08
STAD	chr8	47821754	Silent	novel	T2987T	0.3
STAD	chr8	47912415	Missense_Mutation	NA	D977N	0.13
STAD	chr8	47859634	Missense_Mutation	novel	A2062T	0.22
STAD	chr8	47929879	Missense_Mutation	novel	N676D	0.28
STAD	chr8	47776926	Missense_Mutation	novel	A4034T	0.1
STAD	chr8	47849478	Missense_Mutation	NA	L2344P	0.23
STAD	chr8	47897240	Silent	NA	L1173L	0.13
STAD	chr8	47859624	Missense_Mutation	NA	R2065H	0.19
STAD	chr8	47902792	Missense_Mutation	novel	G1016R	0.43
STAD	chr8	47828294	Silent	NA	L2817L	0.23
STAD	chr8	47782201	Frame_Shift_Del	novel	L3817*	0.1
STAD	chr8	47864651	Missense_Mutation	NA	T1826A	0.29
STAD	chr8	47799217	Silent	novel	N3430N	0.32
STAD	chr8	47863573	Missense_Mutation	novel	N1859S	0.05
STAD	chr8	47837361	Missense_Mutation	rs375122519	R2538W	0.4
STAD	chr8	47939651	Missense_Mutation	NA	L338P	0.29
STAD	chr8	47902786	Missense_Mutation	rs376896763	V1018M	0.28
STAD	chr8	47788994	Frame_Shift_Del	NA	*N3605Tfs48**	0.3
STAD	chr8	47834238	Frame_Shift_Del	NA	*R2704Gfs13**	0.23
STAD	chr8	47789010	Missense_Mutation	NA	P3600T	0.16
STAD	chr8	47820927	Missense_Mutation	NA	Y3043C	0.05
STAD	chr8	47785165	Silent	NA	P3685P	0.09
STAD	chr8	47834350	Silent	rs769310297	P2666P	0.23
STAD	chr8	47776956	Frame_Shift_Ins	novel	*G4024Rfs12**	0.22
STAD	chr8	47830614	Silent	rs373077938	A2796A	0.1
STAD	chr8	47794383	Missense_Mutation	NA	P3526L	0.14
STAD	chr8	47828255	Frame_Shift_Ins	NA	*N2830Kfs16**	0.17
STAD	chr8	47789191	Missense_Mutation	NA	N3573S	0.24
STAD	chr8	47862382	Silent	NA	K1970K	0.28
STAD	chr8	47904971	Silent	NA	T980T	0.2
STAD	chr8	47859653	Silent	NA	S2055S	0.78
STAD	chr8	47912449	Silent	NA	T965T	0.14
STAD	chr8	47859653	Missense_Mutation	NA	S2055R	0.11
STAD	chr8	47788994	Frame_Shift_Del	NA	*N3605Tfs48**	0.27
TGCT	chr8	47834371	Silent	novel	L2659L	0.09
TGCT	chr8	47837218	Missense_Mutation	novel	E2585D	0.2
THCA	chr8	47886076	Silent	novel	G1548G	0.25
THCA	chr8	47886077	Missense_Mutation	novel	G1548V	0.25
THCA	chr8	47836493	Missense_Mutation	NA	S2599N	0.13
THCA	chr8	47774297	Missense_Mutation	NA	N4088S	0.4
THYM	chr8	47893284	Silent	novel	G1234G	0.29
THYM	chr8	47898527	Missense_Mutation	rs781401034	R1136H	0.3
UCEC	chr8	47840124	Missense_Mutation	novel	V2449A	0.25
UCEC	chr8	47799334	Silent	rs368284467	A3391A	0.38
UCEC	chr8	47849243	Missense_Mutation	NA	C2397W	0.43
UCEC	chr8	47877841	Missense_Mutation	NA	A1749E	0.37
UCEC	chr8	47915337	Missense_Mutation	rs368278587	L870I	0.34
UCEC	chr8	47930788	Splice_Site	NA	X593_splice	0.32
UCEC	chr8	47957397	Silent	rs372416216	F63F	0.31
UCEC	chr8	47881452	Silent	novel	S1677S	0.14
UCEC	chr8	47887675	Nonsense_Mutation	novel	E1482*	0.39
UCEC	chr8	47912453	Missense_Mutation	rs375395171	R964Q	0.32
UCEC	chr8	47890270	Missense_Mutation	rs767489623	P1353L	0.43
UCEC	chr8	47774045	3'UTR	novel		0.18
UCEC	chr8	47776897	Missense_Mutation	NA	K4043N	0.61
UCEC	chr8	47778498	Silent	rs750761283	I3938I	0.41
UCEC	chr8	47807256	Missense_Mutation	novel	Q3210K	0.06
UCEC	chr8	47837408	Missense_Mutation	rs773817275	R2522Q	0.2
UCEC	chr8	47929935	Missense_Mutation	NA	S657F	0.32
UCEC	chr8	47954371	Nonsense_Mutation	NA	E159*	0.44
UCEC	chr8	47774327	Missense_Mutation	novel	V4078A	0.46
UCEC	chr8	47859668	Silent	NA	Q2050Q	0.43
UCEC	chr8	47877835	Missense_Mutation	novel	E1751G	0.4
UCEC	chr8	47879653	Silent	novel	Q1691Q	0.24
UCEC	chr8	47890445	Missense_Mutation	novel	A1295T	0.51
UCEC	chr8	47898468	Splice_Site	novel	X1155_splice	0.32
UCEC	chr8	47935863	Missense_Mutation	novel	V439A	0.06
UCEC	chr8	47936493	Missense_Mutation	novel	D380Y	0.14
UCEC	chr8	47957425	Missense_Mutation	novel	Q54R	0.3
UCEC	chr8	47913928	Silent	rs748858597	A918A	0.3
UCEC	chr8	47776957	Frame_Shift_Del	novel	*G4024Efs8**	0.45
UCEC	chr8	47889051	Missense_Mutation	novel	L1415I	0.58
UCEC	chr8	47774045	3'UTR	novel		0.47
UCEC	chr8	47782585	Missense_Mutation	NA	A3730V	0.36
UCEC	chr8	47854168	Missense_Mutation	NA	N2270D	0.39
UCEC	chr8	47886047	Missense_Mutation	NA	Y1558S	0.38
UCEC	chr8	47898527	Missense_Mutation	rs781401034	R1136H	0.44
UCEC	chr8	47807294	Missense_Mutation	novel	L3197R	0.44
UCEC	chr8	47837408	Missense_Mutation	rs773817275	R2522Q	0.47
UCEC	chr8	47839171	Silent	novel	L2510L	0.45
UCEC	chr8	47912555	Missense_Mutation	novel	A930V	0.33
UCEC	chr8	47930739	Missense_Mutation	novel	A609S	0.35
UCEC	chr8	47933987	Missense_Mutation	novel	L534R	0.16
UCEC	chr8	47788993	Frame_Shift_Ins	NA	*N3605Kfs3**	0.38
UCEC	chr8	47890274	Missense_Mutation	NA	S1352P	0.45
UCEC	chr8	47799382	Silent	novel	A3375A	0.13
UCEC	chr8	47774292	Missense_Mutation	NA	R4090C	0.5
UCEC	chr8	47927210	Missense_Mutation	novel	K801N	0.46
UCEC	chr8	47933064</

EuRBPDB

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