EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr19	54462519	Missense_Mutation	novel	Q336H	0.21	AKAP7_NLS
BLCA	chr19	54462447	Silent	novel	L360L	0.18
BLCA	chr19	54462886	Missense_Mutation	novel	A214V	0.37
BLCA	chr19	54462192	Silent	novel	L445L	0.46
BRCA	chr19	54462656	Frame_Shift_Del	novel	*D282Pfs15**	0.58
CESC	chr19	54463108	Missense_Mutation	novel	S140W	0.24
COAD	chr19	54462125	Frame_Shift_Ins	rs757537115	*P468Afs7**	0.47
COAD	chr19	54462888	Silent	novel	A213A	0.45
COAD	chr19	54462816	Silent	novel	V237V	0.19
COAD	chr19	54462770	Missense_Mutation	novel	G253W	0.11
ESCA	chr19	54462605	Missense_Mutation	novel	P308S	0.17	AKAP7_NLS
ESCA	chr19	54462272	Missense_Mutation	rs756283596	G419R	0.22	AKAP7_NLS
ESCA	chr19	54462537	Silent	novel	N330N	0.24
GBM	chr19	54462051	3'UTR	novel		0.16
HNSC	chr19	54462570	Frame_Shift_Del	novel	*E319Dfs14**	0.42	AKAP7_NLS
HNSC	chr19	54462203	Missense_Mutation	novel	E442Q	0.15	AKAP7_NLS
HNSC	chr19	54462474	Silent	novel	G351G	0.25
HNSC	chr19	54462714	Missense_Mutation	novel	E271D	0.13
HNSC	chr19	54462673	Missense_Mutation	novel	A285V	0.17
LGG	chr19	54462894	Silent	novel	L211L	0.24
LGG	chr19	54462942	Silent	rs765760584	P195P	0.19
LGG	chr19	54462280	Frame_Shift_Del	rs778740821	*Q416Vfs58**	0.47	AKAP7_NLS
LGG	chr19	54462608	Missense_Mutation	rs142325287	E307K	0.44	AKAP7_NLS
LIHC	chr19	54462937	Missense_Mutation	novel	C197F	0.09
LIHC	chr19	54463156	Frame_Shift_Del	novel	*R124Pfs114**	0.32
LUAD	chr19	54462105	Missense_Mutation	novel	E474D	0.15
LUSC	chr19	54462135	Silent	rs771904400	R464R	0.31
LUSC	chr19	54462971	Missense_Mutation	novel	A186S	0.22
LUSC	chr19	54462965	Frame_Shift_Ins	novel	*P188Cfs38**	0.42
LUSC	chr19	54463014	Missense_Mutation	novel	E171D	0.16
LUSC	chr19	54462572	Missense_Mutation	novel	E319K	0.26	AKAP7_NLS
LUSC	chr19	54462275	Missense_Mutation	novel	P418A	0.27	AKAP7_NLS
LUSC	chr19	54463108	Missense_Mutation	rs766062750	S140L	0.42
LUSC	chr19	54462822	Silent	novel	A235A	0.31
LUSC	chr19	54462407	Missense_Mutation	novel	R374W	0.24	AKAP7_NLS
OV	chr19	54462798	Frame_Shift_Ins	novel	*T244Dfs29**	0.06
READ	chr19	54462534	Missense_Mutation	novel	F331L	0.55	AKAP7_NLS
SKCM	chr19	54462041	3'UTR	novel		0.34
SKCM	chr19	54462926	Nonsense_Mutation	novel	Q201*	0.43
SKCM	chr19	54462927	Silent	novel	H200H	0.42
STAD	chr19	54462766	Frame_Shift_Del	novel	*G254Afs52**	0.18
STAD	chr19	54462477	Silent	novel	A350A	0.12
STAD	chr19	54463072	Missense_Mutation	novel	A152V	0.25
STAD	chr19	54462960	Missense_Mutation	novel	K189N	0.11
STAD	chr19	54462409	Frame_Shift_Del	novel	*P373Lfs3**	0.37	AKAP7_NLS
STAD	chr19	54462152	Silent	rs139044470	L459L	0.41
STAD	chr19	54462191	Missense_Mutation	novel	S446C	0.35	AKAP7_NLS
STAD	chr19	54462280	Frame_Shift_Del	rs778740821	*Q416Vfs58**	0.13	AKAP7_NLS
THCA	chr19	54462720	Frame_Shift_Del	novel	*T270Qfs36**	0.05
UCEC	chr19	54462404	Silent	novel	L375L	0.34
UCEC	chr19	54463097	Missense_Mutation	novel	L144F	0.33
UCEC	chr19	54462426	Silent	novel	P367P	0.31
UCEC	chr19	54462076	3'UTR	novel		0.21
UCEC	chr19	54462557	Missense_Mutation	novel	V324M	0.16	AKAP7_NLS
UCEC	chr19	54462684	Missense_Mutation	novel	E281D	0.13
UCEC	chr19	54462373	Missense_Mutation	rs542592473	P385L	0.54	AKAP7_NLS
UCEC	chr19	54462340	Missense_Mutation	novel	L396P	0.39	AKAP7_NLS
UCEC	chr19	54462579	Missense_Mutation	novel	K316N	0.25	AKAP7_NLS
UCEC	chr19	54462491	Nonsense_Mutation	novel	R346*	0.33	AKAP7_NLS
UCEC	chr19	54462409	Frame_Shift_Del	novel	*P373Lfs3**	0.43	AKAP7_NLS
UCEC	chr19	54462530	Missense_Mutation	novel	V333M	0.33	AKAP7_NLS
UCEC	chr19	54462426	Silent	rs375081831	P367P	0.38
UCEC	chr19	54462640	Missense_Mutation	rs368668472	R296H	0.3
UCEC	chr19	54462728	Missense_Mutation	rs757534030	A267T	0.42
UCEC	chr19	54462652	Frame_Shift_Del	novel	*P292Lfs14**	0.52
UCEC	chr19	54462299	Nonsense_Mutation	novel	E410*	0.09	AKAP7_NLS
UCEC	chr19	54462542	Missense_Mutation	rs755113750	A329T	0.28	AKAP7_NLS
UCEC	chr19	54462711	Silent	rs376993009	A272A	0.37
UCEC	chr19	54462285	Silent	novel	T414T	0.4
UCEC	chr19	54462095	Missense_Mutation	novel	E478K	0.4
UCEC	chr19	54462175	Missense_Mutation	novel	C451Y	0.47	AKAP7_NLS
UCEC	chr19	54462377	Missense_Mutation	novel	G384S	0.45	AKAP7_NLS
UCEC	chr19	54462491	Nonsense_Mutation	novel	R346*	0.43	AKAP7_NLS
UCEC	chr19	54462162	Silent	novel	Q455Q	0.23
UCEC	chr19	54462289	Missense_Mutation	novel	S413I	0.5	AKAP7_NLS
UCS	chr19	54462042	3'UTR	novel		0.38

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BLCA	AMP	0.3113	0.013691
CESC	DEL	0.0712	0.027508
KIRP	DEL	0.0486	0.054726
LGG	DEL	0.4971	1.4433e-28
PAAD	DEL	0.0761	0.035089
PRAD	AMP	0.0346	0.17703
READ	DEL	0.097	0.23023
TGCT	DEL	0.2867	0.0046229
UCS	DEL	0.1607	0.12448

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0001	Kaplan-Meier Survival Analysis
STAD	0.0015	Kaplan-Meier Survival Analysis
ACC	0.016	Kaplan-Meier Survival Analysis
HNSC	0.0032	Kaplan-Meier Survival Analysis
PAAD	0.041	Kaplan-Meier Survival Analysis
LAML	0.027	Kaplan-Meier Survival Analysis
UCEC	0.00017	Kaplan-Meier Survival Analysis
GBM	0.00018	Kaplan-Meier Survival Analysis
LGG	0.0001	Kaplan-Meier Survival Analysis
CHOL	0.027	Kaplan-Meier Survival Analysis
UVM	0.0061	Kaplan-Meier Survival Analysis

Description

RBDs

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000275183 (Gene tree)
Gene ID: 94059
Gene Symbol: LENG9
Alias: N
Full Name: leukocyte receptor cluster member 9
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 1,916 bases
Position: chr19:54,461,796-54,463,711
Accession: 16306
RBP type: canonical RBP
Summary: (Leukocyte Receptor Cluster Member 9) is a Protein Coding gene. An important paralog of this gene is NUP42.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000479355	AKAP7_NLS	PF10469.9	2.2e-15	1	1

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000611161	LENG9-203	1916	-	ENSP00000479355	478 (aa)	-	A0A087WVD1

Gene Model

Click here to download ENSG00000275183's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000275183's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000275183	LENG9	62	53.543	ENSAPOG00000016038	-	94	32.967	Acanthochromis_polyacanthus
ENSG00000275183	LENG9	65	43.949	ENSAOCG00000012343	-	89	30.297	Amphiprion_ocellaris
ENSG00000275183	LENG9	65	43.312	ENSAPEG00000008438	-	89	30.196	Amphiprion_percula
ENSG00000275183	LENG9	99	33.198	ENSACAG00000016906	LENG9	94	33.535	Anolis_carolinensis
ENSG00000275183	LENG9	81	79.310	ENSBTAG00000011693	LENG9	99	56.015	Bos_taurus
ENSG00000275183	LENG9	100	86.458	ENSCJAG00000001244	LENG9	100	86.458	Callithrix_jacchus
ENSG00000275183	LENG9	99	61.587	ENSCHIG00000016786	LENG9	99	61.378	Capra_hircus
ENSG00000275183	LENG9	76	50.785	ENSCPBG00000016763	LENG9	88	52.632	Chrysemys_picta_bellii
ENSG00000275183	LENG9	98	61.523	ENSCGRG00001004238	Leng9	97	61.814	Cricetulus_griseus_chok1gshd
ENSG00000275183	LENG9	94	30.937	ENSCSEG00000018718	-	99	30.937	Cynoglossus_semilaevis
ENSG00000275183	LENG9	95	30.242	ENSCVAG00000007812	-	94	30.185	Cyprinodon_variegatus
ENSG00000275183	LENG9	95	59.915	ENSDNOG00000005144	LENG9	96	59.660	Dasypus_novemcinctus
ENSG00000275183	LENG9	95	62.140	ENSEASG00005021529	LENG9	99	61.983	Equus_asinus_asinus
ENSG00000275183	LENG9	99	61.886	ENSECAG00000018281	LENG9	99	62.672	Equus_caballus
ENSG00000275183	LENG9	92	31.070	ENSGACG00000010726	-	96	30.474	Gasterosteus_aculeatus
ENSG00000275183	LENG9	71	53.704	ENSGAGG00000018912	LENG9	77	53.691	Gopherus_agassizii
ENSG00000275183	LENG9	64	52.000	ENSLACG00000012924	LENG9	79	50.000	Latimeria_chalumnae
ENSG00000275183	LENG9	82	52.955	ENSLAFG00000025939	-	97	52.955	Loxodonta_africana
ENSG00000275183	LENG9	100	67.223	ENSMFAG00000037144	LENG9	100	68.267	Macaca_fascicularis
ENSG00000275183	LENG9	100	72.500	ENSMMUG00000021631	LENG9	96	72.500	Macaca_mulatta
ENSG00000275183	LENG9	100	73.958	ENSMNEG00000036994	LENG9	100	73.958	Macaca_nemestrina
ENSG00000275183	LENG9	93	47.768	ENSMODG00000023541	-	95	47.982	Monodelphis_domestica
ENSG00000275183	LENG9	95	60.788	MGP_CAROLIEiJ_G0029106	Leng9	98	60.915	Mus_caroli
ENSG00000275183	LENG9	98	59.838	ENSMUSG00000043432	Leng9	97	60.499	Mus_musculus
ENSG00000275183	LENG9	98	61.663	MGP_PahariEiJ_G0020974	Leng9	97	62.370	Mus_pahari
ENSG00000275183	LENG9	98	60.526	MGP_SPRETEiJ_G0030159	Leng9	97	61.203	Mus_spretus
ENSG00000275183	LENG9	94	63.694	ENSMPUG00000018631	LENG9	99	63.694	Mustela_putorius_furo
ENSG00000275183	LENG9	100	86.221	ENSNLEG00000019192	LENG9	100	86.221	Nomascus_leucogenys
ENSG00000275183	LENG9	61	74.820	ENSOANG00000005166	-	80	74.820	Ornithorhynchus_anatinus
ENSG00000275183	LENG9	90	50.417	ENSOARG00000002644	-	90	50.734	Ovis_aries
ENSG00000275183	LENG9	97	63.694	ENSPPRG00000012303	LENG9	97	63.181	Panthera_pardus
ENSG00000275183	LENG9	100	98.747	ENSPTRG00000050721	-	96	98.747	Pan_troglodytes
ENSG00000275183	LENG9	100	98.956	ENSPTRG00000011460	-	96	98.956	Pan_troglodytes
ENSG00000275183	LENG9	84	31.678	ENSPMGG00000012138	-	96	31.678	Periophthalmus_magnuspinnatus
ENSG00000275183	LENG9	98	60.446	ENSPEMG00000006776	Leng9	97	60.707	Peromyscus_maniculatus_bairdii
ENSG00000275183	LENG9	73	70.513	ENSPCIG00000009911	-	85	70.470	Phascolarctos_cinereus
ENSG00000275183	LENG9	100	93.528	ENSPPYG00000010383	LENG9	100	93.528	Pongo_abelii
ENSG00000275183	LENG9	99	62.834	ENSPCAG00000005749	LENG9	99	62.834	Procavia_capensis
ENSG00000275183	LENG9	95	60.291	ENSRNOG00000018621	Leng9	97	60.291	Rattus_norvegicus
ENSG00000275183	LENG9	71	30.923	ENSSDUG00000008877	-	86	30.426	Seriola_dumerili
ENSG00000275183	LENG9	71	30.769	ENSSLDG00000022376	-	87	30.080	Seriola_lalandi_dorsalis
ENSG00000275183	LENG9	64	50.962	ENSSPUG00000002762	LENG9	99	32.422	Sphenodon_punctatus
ENSG00000275183	LENG9	99	57.196	ENSSSCG00000003269	LENG9	99	56.449	Sus_scrofa
ENSG00000275183	LENG9	95	33.049	ENSTNIG00000008093	-	99	32.623	Tetraodon_nigroviridis
ENSG00000275183	LENG9	99	63.673	ENSTTRG00000006593	LENG9	99	64.490	Tursiops_truncatus
ENSG00000275183	LENG9	97	67.021	ENSUAMG00000009573	LENG9	91	66.812	Ursus_americanus
ENSG00000275183	LENG9	67	54.795	ENSXETG00000027476	leng9	78	54.545	Xenopus_tropicalis

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0046872	metal ion binding	-	IEA	Function

Note: Click here to get the extension of tumor abbreviations.

Note: to get the extension of tumor abbreviations.