EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
29056512	Acetyl-CoA Carboxylase 1-Dependent Protein Acetylation Controls Breast Cancer Metastasis and Recurrence.	Cell Metab	2017 Dec 5	Rios Garcia M	doi: 10.1016/j.cmet.2017.09.018
24924473	Increased expression of phospho-acetyl-CoA carboxylase protein is an independent prognostic factor for human gastric cancer without lymph node metastasis.	Med Oncol	2014 Jul	Fang W	doi: 10.1007/s12032-014-0015-7
16326698	BRCA1 affects lipid synthesis through its interaction with acetyl-CoA carboxylase.	J Biol Chem	2006 Feb 10	Moreau K	-
21726077	The lipogenesis pathway as a cancer target.	J Med Chem	2011 Aug 25	Abramson HN	doi: 10.1021/jm2005805
25246709	Chemical inhibition of acetyl-CoA carboxylase suppresses self-renewal growth of cancer stem cells.	Oncotarget	2014 Sep 30	Corominas-Faja B	-
18056116	Aldo-keto reductase family 1 B10 affects fatty acid synthesis by regulating the stability of acetyl-CoA carboxylase-alpha in breast cancer cells.	J Biol Chem	2008 Feb 8	Ma J	-
17372234	Haplotype-based analysis of common variation in the acetyl-coA carboxylase alpha gene and breast cancer risk: a case-control study nested within the European Prospective Investigation into Cancer and Nutrition.	Cancer Epidemiol Biomarkers Prev	2007 Mar	Sinilnikova OM	-
19710915	Inhibition of stearoylCoA desaturase-1 inactivates acetyl-CoA carboxylase and impairs proliferation in cancer cells: role of AMPK.	PLoS One	2009 Aug 27	Scaglia N	doi: 10.1371/journal.pone.0006812.
17631500	Up-regulation of acetyl-CoA carboxylase alpha and fatty acid synthase by human epidermal growth factor receptor 2 at the translational level in breast cancer cells.	J Biol Chem	2007 Sep 7	Yoon S	-
15333468	Acetyl-CoA carboxylase alpha gene and breast cancer susceptibility.	Carcinogenesis	2004 Dec	Sinilnikova OM	-
27693630	Acetyl-CoA carboxylase rewires cancer metabolism to allow cancer cells to survive inhibition of the Warburg effect by cetuximab.	Cancer Lett	2017 Jan 1	Luo J	doi: 10.1016/j.canlet.2016.09.020
29899443	Structural basis for regulation of human acetyl-CoA carboxylase.	Nature	2018 Jun	Hunkeler M	doi: 10.1038/s41586-018-0201-4

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
ACC	chr17	37111591	Missense_Mutation	novel	D2169Y	0.12
BLCA	chr17	37188403	Silent	novel	L1550L	0.29
BLCA	chr17	37284867	Missense_Mutation	novel	R148C	0.1
BLCA	chr17	37191156	Silent	novel	L1512L	0.21
BLCA	chr17	37149959	Missense_Mutation	novel	I1862V	0.26
BLCA	chr17	37111550	Missense_Mutation	novel	I2182M	0.36
BLCA	chr17	37252942	Nonsense_Mutation	novel	Q641*	0.19
BLCA	chr17	37155727	Silent	rs757250697	L1801L	0.12
BLCA	chr17	37088979	Missense_Mutation	novel	I2329M	0.04
BLCA	chr17	37129436	Missense_Mutation	novel	R1958T	0.11
BLCA	chr17	37223596	Silent	rs753127166	L1160L	0.09
BLCA	chr17	37246967	Silent	novel	I773I	0.24
BLCA	chr17	37192292	Missense_Mutation	novel	R1405L	0.38
BLCA	chr17	37277922	Missense_Mutation	novel	D232N	0.15
BLCA	chr17	37235064	Missense_Mutation	novel	E1053Q	0.24
BLCA	chr17	37263831	Missense_Mutation	novel	L395V	0.52
BLCA	chr17	37258349	Silent	novel	R509R	0.18
BLCA	chr17	37275969	Missense_Mutation	novel	L295F	0.46
BLCA	chr17	37161918	Missense_Mutation	novel	R1738G	0.13
BLCA	chr17	37087184	3'UTR	novel		0.83
BLCA	chr17	37263720	Missense_Mutation	novel	I432V	0.08
BLCA	chr17	37258262	Missense_Mutation	rs774611562	P538S	0.12
BLCA	chr17	37270787	Silent	novel	V361V	0.09
BLCA	chr17	37097119	Silent	novel	L2256L	0.67
BLCA	chr17	37097898	Nonsense_Mutation	novel	Q2218*	0.38
BLCA	chr17	37284966	Missense_Mutation	novel	S115G	0.41
BLCA	chr17	37406366	5'UTR	novel		0.14
BLCA	chr17	37097952	Missense_Mutation	novel	E2200Q	0.24
BLCA	chr17	37188397	Silent	novel	I1552I	0.43
BLCA	chr17	37257718	Missense_Mutation	novel	R604K	0.27
BLCA	chr17	37257754	Missense_Mutation	novel	S592C	0.14
BLCA	chr17	37188294	Missense_Mutation	novel	D1587N	0.51
BLCA	chr17	37259522	Silent	novel	V446V	0.28
BLCA	chr17	37339825	Missense_Mutation	novel	Q22E	0.17
BLCA	chr17	37221735	Silent	novel	S1224S	0.2
BLCA	chr17	37155727	Silent	rs757250697	L1801L	0.33
BRCA	chr17	37097065	Silent	novel	P2274P	0.31
BRCA	chr17	37113186	Silent	rs779109355	Y2118Y	0.1
BRCA	chr17	37121384	Missense_Mutation	novel	N2082S	0.23
BRCA	chr17	37240480	Missense_Mutation	novel	Q1039H	0.18
BRCA	chr17	37086939	3'UTR	novel		0.07
BRCA	chr17	37205773	Missense_Mutation	novel	Q1350K	0.13
BRCA	chr17	37206794	Missense_Mutation	novel	D1313H	0.05
BRCA	chr17	37221734	Missense_Mutation	novel	H1225Y	0.1
BRCA	chr17	37252978	Missense_Mutation	novel	E629K	0.17
BRCA	chr17	37149910	Missense_Mutation	novel	V1878A	0.24
BRCA	chr17	37284933	Nonsense_Mutation	novel	R126*	0.23
BRCA	chr17	37258311	Silent	novel	P521P	0.21
BRCA	chr17	37087143	3'UTR	novel		0.18
BRCA	chr17	37087054	3'UTR	novel		0.21
BRCA	chr17	37257700	Splice_Region	novel		0.33
BRCA	chr17	37097119	Silent	novel	L2256L	0.38
BRCA	chr17	37161910	Silent	novel	S1740S	0.32
BRCA	chr17	37259510	Missense_Mutation	novel	K450N	0.16
BRCA	chr17	37284860	Missense_Mutation	novel	G150E	0.18
BRCA	chr17	37111599	Missense_Mutation	novel	R2166H	0.19
BRCA	chr17	37206872	Missense_Mutation	novel	D1287H	0.43
BRCA	chr17	37248595	Nonsense_Mutation	novel	K721*	0.53
CESC	chr17	37330233	Missense_Mutation	novel	S93L	0.22
CESC	chr17	37299314	Intron	novel		0.43
CESC	chr17	37130161	Missense_Mutation	novel	H1913Y	0.25
CESC	chr17	37257847	Frame_Shift_Ins	novel	*G561Efs12**	0.12
CESC	chr17	37097055	Missense_Mutation	novel	D2278H	0.42
CESC	chr17	37149965	Missense_Mutation	rs758980216	R1860W	0.43
CESC	chr17	37192124	Missense_Mutation	novel	R1461H	0.34
CESC	chr17	37258319	Missense_Mutation	novel	V519I	0.42
CESC	chr17	37248110	Missense_Mutation	novel	S737L	0.26
CESC	chr17	37406303	5'UTR	novel		0.3
CESC	chr17	37129472	Nonsense_Mutation	novel	S1946*	0.26
CESC	chr17	37221791	Missense_Mutation	novel	R1206C	0.36
CESC	chr17	37406433	5'UTR	novel		0.18
CESC	chr17	37122594	Frame_Shift_Del	novel	*E2026Kfs5**	0.24
CESC	chr17	37087043	3'UTR	novel		0.35
COAD	chr17	37257850	Missense_Mutation	novel	S560L	0.44
COAD	chr17	37191145	Missense_Mutation	novel	P1516H	0.33
COAD	chr17	37192125	Missense_Mutation	rs769240769	R1461C	0.31
COAD	chr17	37235076	Missense_Mutation	rs758519292	A1049T	0.44
COAD	chr17	37263748	Missense_Mutation	novel	Q422H	0.28
COAD	chr17	37244601	Missense_Mutation	novel	F910S	0.09
COAD	chr17	37113122	Missense_Mutation	novel	R2140W	0.4
COAD	chr17	37188389	Missense_Mutation	rs764599804	R1555H	0.3
COAD	chr17	37283329	Missense_Mutation	novel	R183Q	0.31
COAD	chr17	37274231	Nonsense_Mutation	novel	E324*	0.39
COAD	chr17	37284890	Missense_Mutation	novel	A140V	0.35
COAD	chr17	37252903	Missense_Mutation	novel	I654L	0.1
COAD	chr17	37130200	Missense_Mutation	novel	Y1900H	0.16
COAD	chr17	37235038	Silent	novel	V1061V	0.31
COAD	chr17	37248058	Silent	novel	S754S	0.43
COAD	chr17	37130073	Splice_Site	novel	X1941_splice	0.14
COAD	chr17	37221632	Intron	novel		0.16
COAD	chr17	37248076	Silent	rs369806793	D748D	0.85
COAD	chr17	37113122	Silent	novel	R2140R	0.27
COAD	chr17	37111570	Missense_Mutation	rs778168950	R2176W	0.45
COAD	chr17	37246878	Missense_Mutation	novel	I803T	0.33
COAD	chr17	37235091	Missense_Mutation	novel	D1044N	0.07
COAD	chr17	37248076	Silent	rs369806793	D748D	0.36
COAD	chr17	37240559	Missense_Mutation	novel	R1013Q	0.46
COAD	chr17	37129483	Splice_Region	rs201284070	S1942S	0.19
COAD	chr17	37221632	Intron	novel		0.4
COAD	chr17	37240526	Missense_Mutation	novel	V1024A	0.15
COAD	chr17	37122717	Intron	novel		0.11
COAD	chr17	37161995	Missense_Mutation	novel	R1712Q	0.07
COAD	chr17	37246900	Missense_Mutation	novel	A796S	0.15
COAD	chr17	37207744	Missense_Mutation	rs758156281	S1255N	0.08
COAD	chr17	37252057	Missense_Mutation	novel	A677P	0.37
COAD	chr17	37097829	Splice_Site	novel	X2240_splice	0.09
COAD	chr17	37130080	Missense_Mutation	novel	P1940T	0.11
COAD	chr17	37221708	Intron	novel		0.08
COAD	chr17	37283329	Missense_Mutation	novel	R183Q	0.09
COAD	chr17	37330244	Silent	novel	A89A	0.04
COAD	chr17	37129395	Nonsense_Mutation	novel	R1972*	0.33
COAD	chr17	37258302	Missense_Mutation	novel	D524E	0.18
COAD	chr17	37206875	Missense_Mutation	novel	F1286V	0.14
COAD	chr17	37226350	Nonsense_Mutation	novel	R1117*	0.21
COAD	chr17	37188450	Missense_Mutation	novel	R1535W	0.28
COAD	chr17	37277925	Missense_Mutation	novel	L231I	0.25
COAD	chr17	37235017	Silent	rs112050484	H1068H	0.49
COAD	chr17	37129401	Missense_Mutation	rs765097577	D1970N	0.49
COAD	chr17	37299327	Intron	rs777706096		0.06
COAD	chr17	37161903	Missense_Mutation	rs199723320	A1743T	0.2
COAD	chr17	37129460	Missense_Mutation	novel	L1950Q	0.27
COAD	chr17	37192158	Missense_Mutation	novel	G1450S	0.36
COAD	chr17	37149887	In_Frame_Ins	novel	L1885_T1886insY	0.11
COAD	chr17	37097953	Frame_Shift_Ins	novel	*E2200Gfs26**	0.48
COAD	chr17	37193385	Missense_Mutation	novel	A1397T	0.11
DLBC	chr17	37252978	Missense_Mutation	novel	E629K	0.19
ESCA	chr17	37210476	Missense_Mutation	novel	T1233M	0.49
ESCA	chr17	37330369	Missense_Mutation	novel	L48V	0.08
ESCA	chr17	37277040	Silent	novel	A265A	0.49
ESCA	chr17	37161999	Missense_Mutation	novel	G1711S	0.38
ESCA	chr17	37089062	Missense_Mutation	novel	D2302N	0.35
ESCA	chr17	37242005	Missense_Mutation	novel	E994Q	0.25
ESCA	chr17	37161983	Missense_Mutation	novel	V1716A	0.33
ESCA	chr17	37207782	Missense_Mutation	novel	N1242K	0.2
ESCA	chr17	37221593	Intron	novel		0.25
GBM	chr17	37188407	Missense_Mutation	novel	E1549V	0.1
GBM	chr17	37241980	Missense_Mutation	novel	T1002I	0.15
GBM	chr17	37277104	Frame_Shift_Del	novel	*A244Vfs17**	0.39
GBM	chr17	37274261	Missense_Mutation	novel	R314C	0.73
GBM	chr17	37248038	Missense_Mutation	novel	T761S	0.07
GBM	chr17	37122720	Intron	novel		0.4
GBM	chr17	37207703	Missense_Mutation	novel	R1269W	0.43
GBM	chr17	37284915	Missense_Mutation	novel	D132Y	0.18
GBM	chr17	37277057	Silent	novel	L260L	0.17
GBM	chr17	37257823	Missense_Mutation	rs781293486	R569H	0.49
GBM	chr17	37244600	Missense_Mutation	novel	F910L	0.03
GBM	chr17	37240549	Silent	novel	I1016I	0.32
GBM	chr17	37257703	Missense_Mutation	novel	S609L	0.11
GBM	chr17	37087320	Missense_Mutation	rs762756380	T2383M	0.86
GBM	chr17	37206818	Missense_Mutation	novel	E1305Q	0.1
GBM	chr17	37248024	Nonsense_Mutation	novel	E766*	0.52
GBM	chr17	37258340	Missense_Mutation	novel	D512H	0.17
HNSC	chr17	37257865	Missense_Mutation	novel	G555D	0.23
HNSC	chr17	37200165	Missense_Mutation	novel	N1378D	0.07
HNSC	chr17	37248075	Missense_Mutation	novel	G749S	0.12
HNSC	chr17	37225079	Silent	novel	S1129S	0.07
HNSC	chr17	37299332	Intron	novel		0.2
HNSC	chr17	37207771	Missense_Mutation	rs749437417	Y1246C	0.18
HNSC	chr17	37274293	Missense_Mutation	rs73982299	R303H	0.34
HNSC	chr17	37277114	Missense_Mutation	novel	A241S	0.19
HNSC	chr17	37223547	Missense_Mutation	novel	H1177D	0.23
HNSC	chr17	37235069	Missense_Mutation	novel	R1051Q	0.16
HNSC	chr17	37243456	Missense_Mutation	rs371689992	P949H	0.13
HNSC	chr17	37257825	Silent	novel	F568F	0.2
HNSC	chr17	37111613	Silent	novel	V2161V	0.27
HNSC	chr17	37263777	Missense_Mutation	novel	R413C	0.09
HNSC	chr17	37245085	Missense_Mutation	novel	Q864E	0.06
HNSC	chr17	37243378	Missense_Mutation	novel	S975N	0.1
HNSC	chr17	37274206	Missense_Mutation	novel	D332V	0.18
HNSC	chr17	37243411	Missense_Mutation	novel	S964N	0.31
HNSC	chr17	37192178	Missense_Mutation	novel	G1443E	0.18
HNSC	chr17	37113258	Silent	rs372559158	Y2094Y	0.09
HNSC	chr17	37257817	Frame_Shift_Del	novel	*N571Ifs45**	0.16
HNSC	chr17	37192292	Missense_Mutation	rs779594669	R1405H	0.35
HNSC	chr17	37284959	Missense_Mutation	novel	S117C	0.14
KIRC	chr17	37243435	Missense_Mutation	rs760725326	K956R	0.33
KIRC	chr17	37188460	Missense_Mutation	novel	S1531R	0.13
KIRP	chr17	37181234	Silent	novel	T1633T	0.61
KIRP	chr17	37263813	Missense_Mutation	novel	A401P	0.08
KIRP	chr17	37258359	Silent	novel	I505I	0.57
KIRP	chr17	37192297	Missense_Mutation	novel	E1403D	0.34
KIRP	chr17	37253027	Silent	novel	V612V	0.64
LAML	chr17	37122577	Missense_Mutation	novel	E2031G	0.18
LAML	chr17	37283271	Missense_Mutation	novel	N202K	0.26
LAML	chr17	37248033	Missense_Mutation	novel	Y763H	0.1
LGG	chr17	37192125	Missense_Mutation	rs769240769	R1461C	0.52
LGG	chr17	37243540	Missense_Mutation	rs770987352	R921Q	0.25
LGG	chr17	37188420	Missense_Mutation	novel	V1545I	0.22
LGG	chr17	37223523	Missense_Mutation	novel	A1185T	0.13
LGG	chr17	37284972	Splice_Site	novel	X113_splice	0.14
LGG	chr17	37283272	Missense_Mutation	novel	N202S	0.26
LGG	chr17	37243394	Missense_Mutation	novel	L970F	0.39
LGG	chr17	37244680	Missense_Mutation	novel	E884K	0.35
LGG	chr17	37097940	Nonsense_Mutation	novel	K2204*	0.14
LIHC	chr17	37263759	Missense_Mutation	rs747343847	R419C	0.44
LIHC	chr17	37274220	Silent	novel	Y327Y	0.32
LIHC	chr17	37406340	5'UTR	novel		0.35
LIHC	chr17	37406341	5'UTR	novel		0.33
LIHC	chr17	37257812	Missense_Mutation	novel	N573D	0.11
LIHC	chr17	37097899	Frame_Shift_Del	novel	*Y2216Rfs2**	0.23
LIHC	chr17	37129412	Frame_Shift_Del	novel	*K1966Rfs10**	0.37
LIHC	chr17	37299502	Intron	novel		0.39
LIHC	chr17	37299359	Intron	novel		0.44
LIHC	chr17	37258324	Missense_Mutation	novel	Y517F	0.17
LIHC	chr17	37188286	Silent	novel	R1589R	0.41
LIHC	chr17	37181305	Missense_Mutation	novel	I1610V	0.5
LUAD	chr17	37330389	Missense_Mutation	novel	P41L	0.16
LUAD	chr17	37221744	Silent	novel	L1221L	0.2
LUAD	chr17	37207723	Missense_Mutation	novel	S1262L	0.11
LUAD	chr17	37087239	3'UTR	novel		0.18
LUAD	chr17	37129478	Missense_Mutation	novel	H1944L	0.16
LUAD	chr17	37258368	Frame_Shift_Del	novel	*M503Wfs13**	0.25
LUAD	chr17	37149959	Missense_Mutation	novel	I1862F	0.24
LUAD	chr17	37206869	Missense_Mutation	novel	E1288K	0.06
LUAD	chr17	37206870	Nonsense_Mutation	novel	*D1287Efs3**	0.07
LUAD	chr17	37406305	5'UTR	novel		0.3
LUAD	chr17	37257745	Missense_Mutation	novel	G595V	0.06
LUAD	chr17	37284926	Missense_Mutation	novel	R128K	0.2
LUAD	chr17	37235013	Missense_Mutation	novel	Q1070E	0.11
LUAD	chr17	37406270	Missense_Mutation	novel	L10F	0.12
LUAD	chr17	37161897	Frame_Shift_Del	novel	*A1745Qfs32**	0.56
LUAD	chr17	37257839	Nonsense_Mutation	novel	Q564*	0.04
LUAD	chr17	37097023	Missense_Mutation	novel	W2288C	0.56
LUAD	chr17	37155722	Missense_Mutation	novel	S1803C	0.21
LUAD	chr17	37252942	Nonsense_Mutation	novel	Q641*	0.05
LUAD	chr17	37149908	Missense_Mutation	novel	E1879K	0.16
LUAD	chr17	37089040	Frame_Shift_Ins	novel	*E2309Gfs164**	0.07
LUAD	chr17	37270823	Silent	novel	A349A	0.19
LUAD	chr17	37130177	Silent	novel	G1907G	0.07
LUAD	chr17	37221687	Intron	novel		0.07
LUAD	chr17	37283363	Silent	novel	R172R	0.25
LUAD	chr17	37089041	Nonsense_Mutation	rs750543369	E2309*	0.14
LUAD	chr17	37149911	Missense_Mutation	novel	V1878F	0.11
LUAD	chr17	37330349	Silent	novel	S54S	0.14
LUAD	chr17	37245199	Missense_Mutation	novel	M826V	0.06
LUSC	chr17	37087184	3'UTR	novel		0.33
LUSC	chr17	37234987	Silent	rs768329159	V1078V	0.22
LUSC	chr17	37192180	Silent	rs61746137	L1442L	0.3
LUSC	chr17	37225033	Missense_Mutation	novel	I1145V	0.5
LUSC	chr17	37122545	Missense_Mutation	novel	D2042Y	0.24
LUSC	chr17	37257730	Missense_Mutation	novel	W600L	0.33
LUSC	chr17	37089074	Missense_Mutation	novel	A2298S	0.12
LUSC	chr17	37243411	Missense_Mutation	novel	S964I	0.22
LUSC	chr17	37205869	Missense_Mutation	rs768387542	P1318A	0.36
LUSC	chr17	37122596	Missense_Mutation	novel	V2025L	0.21
LUSC	chr17	37257847	Missense_Mutation	novel	G561E	0.61
LUSC	chr17	37270774	Missense_Mutation	novel	D366Y	0.17
LUSC	chr17	37242012	Silent	novel	R991R	0.43
LUSC	chr17	37274261	Missense_Mutation	novel	R314C	0.4
LUSC	chr17	37130144	Silent	novel	T1918T	0.4
LUSC	chr17	37248157	Splice_Site	novel	X722_splice	0.3
LUSC	chr17	37278006	Splice_Site	novel	X204_splice	0.31
LUSC	chr17	37225024	Missense_Mutation	novel	Y1148H	0.19
LUSC	chr17	37130108	Missense_Mutation	novel	F1930L	0.21
LUSC	chr17	37270821	Missense_Mutation	novel	S350L	0.12
LUSC	chr17	37283357	Missense_Mutation	novel	I174L	0.62
LUSC	chr17	37210491	Splice_Site	novel	X1228_splice	0.07
OV	chr17	37089015	Missense_Mutation	novel	E2317D	0.06
OV	chr17	37206802	Missense_Mutation	novel	S1310F	0.09
OV	chr17	37097914	Silent	novel	L2212L	0.72
OV	chr17	37339815	Frame_Shift_Del	rs752401577	*V24Efs3**	0.09
OV	chr17	37221842	Missense_Mutation	novel	V1189L	0.06
OV	chr17	37252957	Missense_Mutation	novel	E636Q	0.06
OV	chr17	37248016	Silent	novel	V768V	0.03
OV	chr17	37252018	Missense_Mutation	novel	H690Y	0.05
PAAD	chr17	37089073	Missense_Mutation	novel	A2298D	0.19
PAAD	chr17	37097163	Missense_Mutation	novel	I2242V	0.14
PAAD	chr17	37129479	Missense_Mutation	novel	H1944Y	0.12
PAAD	chr17	37192206	Missense_Mutation	novel	A1434T	0.14
PCPG	chr17	37270833	Missense_Mutation	novel	M346T	0.1
PRAD	chr17	37122584	Missense_Mutation	novel	T2029A	0.23
PRAD	chr17	37248657	Missense_Mutation	novel	A700V	0.33
PRAD	chr17	37113151	Missense_Mutation	novel	W2130L	0.36
PRAD	chr17	37179374	Silent	novel	T1655T	0.24
PRAD	chr17	37181275	Missense_Mutation	novel	L1620V	0.37
PRAD	chr17	37206782	Splice_Site	novel	X1316_splice	0.44
PRAD	chr17	37235070	Nonsense_Mutation	rs753014287	R1051*	0.37
PRAD	chr17	37276039	Silent	novel	S271S	0.39
READ	chr17	37188356	Missense_Mutation	novel	R1566H	0.25
READ	chr17	37253005	Missense_Mutation	novel	I620F	0.13
READ	chr17	37263862	Missense_Mutation	novel	F384L	0.34
READ	chr17	37097890	Silent	rs548821816	A2220A	0.24
READ	chr17	37179401	Silent	novel	L1646L	0.34
READ	chr17	37257707	Missense_Mutation	novel	I608V	0.35
READ	chr17	37161828	Missense_Mutation	novel	R1768C	0.39
READ	chr17	37225068	Missense_Mutation	novel	R1133H	0.33
READ	chr17	37192165	Silent	novel	V1447V	0.28
READ	chr17	37242012	Silent	novel	R991R	0.38
SARC	chr17	37258264	Missense_Mutation	novel	C537F	0.85
SKCM	chr17	37111569	Missense_Mutation	novel	R2176Q	0.24
SKCM	chr17	37243499	Missense_Mutation	novel	E935K	0.33
SKCM	chr17	37122714	Intron	novel		0.27
SKCM	chr17	37122715	Intron	novel		0.25
SKCM	chr17	37245128	Silent	novel	G849G	0.46
SKCM	chr17	37130206	Missense_Mutation	novel	E1898K	0.38
SKCM	chr17	37179352	Missense_Mutation	novel	P1663S	0.44
SKCM	chr17	37221693	Intron	novel		0.42
SKCM	chr17	37155685	Splice_Region	novel	S1815S	0.35
SKCM	chr17	37088947	Missense_Mutation	novel	Q2340L	0.33
SKCM	chr17	37088949	Silent	novel	K2339K	0.29
SKCM	chr17	37246905	Missense_Mutation	novel	P794L	0.42
SKCM	chr17	37263839	Frame_Shift_Ins	novel	*S392Ffs23**	0.15
SKCM	chr17	37244605	Missense_Mutation	novel	P909S	0.04
SKCM	chr17	37274245	Missense_Mutation	novel	P319L	0.35
SKCM	chr17	37263715	Silent	novel	A433A	0.08
SKCM	chr17	37257811	Missense_Mutation	novel	N573I	0.25
SKCM	chr17	37263848	Missense_Mutation	novel	A389G	0.47
SKCM	chr17	37270769	Silent	novel	F367F	0.34
SKCM	chr17	37283307	Silent	rs752507997	F190F	0.45
SKCM	chr17	37179352	Missense_Mutation	novel	P1663S	0.47
SKCM	chr17	37205871	Missense_Mutation	novel	V1317A	0.2
SKCM	chr17	37277905	Silent	novel	I237I	0.38
SKCM	chr17	37089007	Missense_Mutation	novel	G2320D	0.33
SKCM	chr17	37111565	Silent	novel	V2177V	0.38
SKCM	chr17	37221792	Silent	novel	H1205H	0.21
SKCM	chr17	37181354	Splice_Region	novel	I1593I	0.22
SKCM	chr17	37179361	Missense_Mutation	novel	P1660S	0.22
SKCM	chr17	37221750	Silent	novel	F1219F	0.4
SKCM	chr17	37299324	Intron	novel		0.4
SKCM	chr17	37258312	Missense_Mutation	novel	P521L	0.24
SKCM	chr17	37200183	Missense_Mutation	novel	D1372N	0.33
SKCM	chr17	37283307	Silent	rs752507997	F190F	0.27
SKCM	chr17	37161828	Missense_Mutation	novel	R1768C	0.35
SKCM	chr17	37339806	Missense_Mutation	novel	R28K	0.23
SKCM	chr17	37149935	Missense_Mutation	novel	R1870W	0.44
SKCM	chr17	37121479	Silent	novel	Q2050Q	0.48
SKCM	chr17	37244660	Silent	novel	F890F	0.07
SKCM	chr17	37188456	Missense_Mutation	novel	V1533I	0.18
SKCM	chr17	37188457	Missense_Mutation	novel	M1532I	0.18
SKCM	chr17	37087305	3'UTR	novel		0.13
SKCM	chr17	37263813	Missense_Mutation	novel	A401T	0.4
SKCM	chr17	37283307	Silent	rs752507997	F190F	0.09
SKCM	chr17	37252960	Silent	novel	L635L	0.36
SKCM	chr17	37191144	Silent	novel	P1516P	0.22
SKCM	chr17	37111601	Silent	novel	F2165F	0.27
SKCM	chr17	37277066	Missense_Mutation	novel	E257K	0.32
SKCM	chr17	37193406	Missense_Mutation	novel	P1390S	0.08
SKCM	chr17	37179355	Missense_Mutation	novel	P1662S	0.29
SKCM	chr17	37258335	Silent	novel	I513I	0.73
SKCM	chr17	37113177	Silent	novel	P2121P	0.19
SKCM	chr17	37097855	Missense_Mutation	novel	R2232Q	0.35
SKCM	chr17	37181354	Splice_Region	novel	I1593I	0.81
SKCM	chr17	37192182	Missense_Mutation	novel	L1442F	0.8
SKCM	chr17	37284949	Silent	novel	H120H	0.79
SKCM	chr17	37257703	Missense_Mutation	novel	S609L	0.46
SKCM	chr17	37161885	Missense_Mutation	novel	P1749S	0.25
STAD	chr17	37188394	Silent	novel	N1553N	0.11
STAD	chr17	37111639	Missense_Mutation	novel	S2153T	0.18
STAD	chr17	37263751	Silent	novel	H421H	0.07
STAD	chr17	37244694	Missense_Mutation	rs764378176	T879M	0.16
STAD	chr17	37258287	Silent	novel	F529F	0.42
STAD	chr17	37223570	Missense_Mutation	novel	D1169V	0.28
STAD	chr17	37113098	Nonsense_Mutation	novel	R2148*	0.3
STAD	chr17	37121475	Missense_Mutation	novel	G2052S	0.21
STAD	chr17	37257787	Missense_Mutation	novel	A581V	0.13
STAD	chr17	37129402	Silent	novel	Y1969Y	0.24
STAD	chr17	37161882	Missense_Mutation	novel	R1750C	0.34
STAD	chr17	37330348	Nonsense_Mutation	novel	R55*	0.26
STAD	chr17	37193398	Missense_Mutation	novel	F1392L	0.35
STAD	chr17	37226343	Missense_Mutation	novel	R1119H	0.4
STAD	chr17	37234977	Missense_Mutation	novel	I1082V	0.04
STAD	chr17	37226397	Missense_Mutation	novel	T1101I	0.35
STAD	chr17	37244681	Silent	novel	G883G	0.15
STAD	chr17	37406293	Missense_Mutation	novel	W3R	0.11
STAD	chr17	37221632	Intron	novel		0.31
STAD	chr17	37179351	Frame_Shift_Del	novel	*P1663Lfs7**	0.14
STAD	chr17	37339823	Frame_Shift_Ins	novel	*T23Dfs18**	0.18
STAD	chr17	37179302	Missense_Mutation	novel	Q1679H	0.32
STAD	chr17	37097835	Missense_Mutation	novel	I2239V	0.05
STAD	chr17	37221632	Intron	novel		0.5
STAD	chr17	37284857	Missense_Mutation	novel	G151E	0.45
STAD	chr17	37122659	Intron	novel		0.57
STAD	chr17	37192133	Missense_Mutation	novel	F1458C	0.22
STAD	chr17	37181256	Missense_Mutation	novel	Q1626R	0.08
STAD	chr17	37130212	Missense_Mutation	novel	G1896R	0.2
STAD	chr17	37097969	Missense_Mutation	novel	S2194T	0.24
STAD	chr17	37258281	Missense_Mutation	novel	D531E	0.22
STAD	chr17	37221632	Intron	novel		0.25
STAD	chr17	37210474	Silent	novel	L1234L	0.2
STAD	chr17	37121415	Missense_Mutation	novel	R2072W	0.08
STAD	chr17	37246971	Missense_Mutation	novel	R772H	0.07
STAD	chr17	37257787	Missense_Mutation	novel	A581V	0.07
TGCT	chr17	37088981	Missense_Mutation	novel	I2329L	0.28
UCEC	chr17	37181215	Nonsense_Mutation	novel	E1640*	0.32
UCEC	chr17	37191272	Missense_Mutation	novel	A1474T	0.34
UCEC	chr17	37235093	Missense_Mutation	rs756018152	Y1043C	0.26
UCEC	chr17	37240559	Missense_Mutation	novel	R1013Q	0.32
UCEC	chr17	37097115	Missense_Mutation	rs761713389	R2258C	0.32
UCEC	chr17	37149906	Missense_Mutation	novel	E1879D	0.32
UCEC	chr17	37221833	Nonsense_Mutation	novel	R1192*	0.32
UCEC	chr17	37235062	Missense_Mutation	novel	E1053D	0.31
UCEC	chr17	37086985	3'UTR	novel		0.11
UCEC	chr17	37097028	Missense_Mutation	novel	R2287C	0.36
UCEC	chr17	37206831	Silent	novel	S1300S	0.45
UCEC	chr17	37244735	Splice_Site	novel	X866_splice	0.52
UCEC	chr17	37248149	Missense_Mutation	novel	R724Q	0.14
UCEC	chr17	37257779	Frame_Shift_Ins	novel	*G584Rfs5**	0.09
UCEC	chr17	37097025	Missense_Mutation	novel	W2288G	0.31
UCEC	chr17	37161906	Missense_Mutation	novel	L1742I	0.39
UCEC	chr17	37240547	Missense_Mutation	novel	R1017Q	0.37
UCEC	chr17	37257824	Missense_Mutation	rs145246486	R569C	0.3
UCEC	chr17	37299453	Intron	novel		0.4
UCEC	chr17	37087088	3'UTR	novel		0.29
UCEC	chr17	37111600	Missense_Mutation	novel	R2166C	0.37
UCEC	chr17	37207673	Missense_Mutation	novel	F1279V	0.19
UCEC	chr17	37270799	Silent	novel	G357G	0.2
UCEC	chr17	37283322	Silent	novel	E185E	0.35
UCEC	chr17	37191142	Missense_Mutation	novel	T1517M	0.22
UCEC	chr17	37087350	Missense_Mutation	rs773877053	R2373Q	0.31
UCEC	chr17	37206869	Nonsense_Mutation	novel	E1288*	0.03
UCEC	chr17	37221673	Intron	novel		0.45
UCEC	chr17	37097951	Missense_Mutation	novel	E2200V	0.43
UCEC	chr17	37243411	Missense_Mutation	novel	S964N	0.54
UCEC	chr17	37151317	Missense_Mutation	novel	I1851T	0.42
UCEC	chr17	37087319	Silent	rs775240328	T2383T	0.32
UCEC	chr17	37085979	3'UTR	novel		0.2
UCEC	chr17	37225001	Missense_Mutation	novel	E1155D	0.27
UCEC	chr17	37244686	Silent	novel	R882R	0.27
UCEC	chr17	37161959	Missense_Mutation	novel	R1724Q	0.3
UCEC	chr17	37263758	Missense_Mutation	novel	R419H	0.05
UCEC	chr17	37111537	Nonsense_Mutation	novel	R2187*	0.22
UCEC	chr17	37406387	5'UTR	novel		0.18
UCEC	chr17	37226437	Missense_Mutation	novel	R1088W	0.11
UCEC	chr17	37122541	Missense_Mutation	novel	S2043F	0.05
UCEC	chr17	37151376	Frame_Shift_Del	novel	*E1832Rfs8**	0.31
UCEC	chr17	37284916	Missense_Mutation	novel	I131M	0.36
UCEC	chr17	37161793	Missense_Mutation	novel	E1779D	0.21
UCEC	chr17	37406461	5'UTR	novel		0.23
UCEC	chr17	37284867	Missense_Mutation	novel	R148C	0.33
UCEC	chr17	37406454	5'UTR	novel		0.45
UCEC	chr17	37221832	Missense_Mutation	novel	R1192Q	0.04
UCEC	chr17	37188463	Silent	novel	R1530R	0.37
UCEC	chr17	37086014	3'UTR	novel		0.67
UCEC	chr17	37192233	Missense_Mutation	novel	N1425H	0.44
UCEC	chr17	37257818	Missense_Mutation	novel	N571D	0.28
UCEC	chr17	37330259	Silent	novel	G84G	0.1
UCEC	chr17	37162016	Missense_Mutation	novel	S1705I	0.32
UCEC	chr17	37206819	Silent	novel	P1304P	0.41
UCEC	chr17	37226434	Missense_Mutation	novel	D1089Y	0.37
UCEC	chr17	37086862	3'UTR	novel		0.3
UCEC	chr17	37181203	Nonsense_Mutation	novel	Q1644*	0.25
UCEC	chr17	37192187	Missense_Mutation	novel	L1440P	0.27
UCEC	chr17	37406330	5'UTR	novel		0.3
UCEC	chr17	37085639	3'UTR	novel		0.28
UCEC	chr17	37097115	Missense_Mutation	rs761713389	R2258C	0.46
UCEC	chr17	37161993	Missense_Mutation	novel	D1713Y	0.34
UCEC	chr17	37242033	Silent	novel	S984S	0.37
UCEC	chr17	37245077	Splice_Region	novel		0.3
UCEC	chr17	37149969	Silent	rs777992403	T1858T	0.44
UCEC	chr17	37284870	Missense_Mutation	novel	T147A	0.23
UCEC	chr17	37087310	3'UTR	novel		0.33
UCEC	chr17	37188437	Missense_Mutation	novel	R1539H	0.48
UCEC	chr17	37263836	Missense_Mutation	rs187880919	R393H	0.42
UCEC	chr17	37330392	Missense_Mutation	novel	E40G	0.05
UCEC	chr17	37087143	3'UTR	novel		0.46
UCEC	chr17	37243446	Missense_Mutation	novel	E952D	0.61
UCEC	chr17	37252009	Nonsense_Mutation	novel	E693*	0.43
UCEC	chr17	37161959	Missense_Mutation	novel	R1724Q	0.28
UCEC	chr17	37259475	Missense_Mutation	novel	Y462C	0.41
UCEC	chr17	37283368	Missense_Mutation	novel	C170Y	0.36
UCEC	chr17	37111534	Missense_Mutation	novel	L2188V	0.31
UCEC	chr17	37161947	Missense_Mutation	novel	F1728S	0.08
UCEC	chr17	37179328	Missense_Mutation	novel	Y1671H	0.29
UCEC	chr17	37235076	Missense_Mutation	rs758519292	A1049T	0.31
UCEC	chr17	37277074	Missense_Mutation	novel	K254T	0.35
UCEC	chr17	37086969	3'UTR	novel		0.32
UCEC	chr17	37221798	Silent	novel	V1203V	0.09
UCEC	chr17	37226389	Missense_Mutation	novel	T1104A	0.26
UCEC	chr17	37270800	Missense_Mutation	novel	G357E	0.31
UCEC	chr17	37111569	Missense_Mutation	novel	R2176Q	0.33
UCEC	chr17	37226384	Missense_Mutation	novel	Q1105H	0.35
UCEC	chr17	37087310	3'UTR	novel		0.49
UCEC	chr17	37149961	Missense_Mutation	novel	A1861V	0.43
UCEC	chr17	37245097	Missense_Mutation	novel	P860S	0.42
UCEC	chr17	37259526	Missense_Mutation	rs570639605	A445V	0.39
UCEC	chr17	37406519	5'UTR	novel		0.52
UCEC	chr17	37245119	Silent	novel	L852L	0.18
UCEC	chr17	37086841	3'UTR	novel		0.23
UCEC	chr17	37097855	Missense_Mutation	novel	R2232Q	0.41
UCEC	chr17	37155750	Missense_Mutation	novel	D1794Y	0.45
UCEC	chr17	37406357	5'UTR	novel		0.22
UCEC	chr17	37129401	Missense_Mutation	rs765097577	D1970N	0.38
UCEC	chr17	37191201	Silent	novel	A1497A	0.38
UCEC	chr17	37191202	Missense_Mutation	novel	A1497V	0.4
UCEC	chr17	37246862	Silent	novel	G808G	0.11
UCEC	chr17	37088945	Missense_Mutation	novel	I2341F	0.35
UCEC	chr17	37161909	Missense_Mutation	novel	E1741K	0.46
UCEC	chr17	37206843	Silent	novel	S1296S	0.45
UCEC	chr17	37221564	Intron	novel		0.24
UCEC	chr17	37243545	Silent	novel	V919V	0.33
UCEC	chr17	37205803	Missense_Mutation	novel	R1340G	0.47
UCEC	chr17	37248112	Silent	novel	G736G	0.23
UCEC	chr17	37111575	In_Frame_Ins	novel	T2173_M2174insSKKKKKREKKKDLVKT	0
UCEC	chr17	37277904	Missense_Mutation	novel	P238T	0.34
UCEC	chr17	37235073	Missense_Mutation	rs547263573	L1050F	0.22
UCEC	chr17	37086815	3'UTR	novel		0.2
UCEC	chr17	37086821	3'UTR	novel		0.37
UCEC	chr17	37221632	Intron	novel		0.21
UCEC	chr17	37161909	Missense_Mutation	novel	E1741K	0.46
UCEC	chr17	37207801	Splice_Site	novel	X1236_splice	0.33
UCEC	chr17	37235062	Missense_Mutation	novel	E1053D	0.43
UCEC	chr17	37257703	Missense_Mutation	novel	S609L	0.43
UCEC	chr17	37330419	Missense_Mutation	novel	R31I	0.43
UCEC	chr17	37244709	Missense_Mutation	novel	P874L	0.36
UCEC	chr17	37111612	Nonsense_Mutation	novel	E2162*	0.19
UCEC	chr17	37161828	Missense_Mutation	novel	R1768C	0.38
UCEC	chr17	37192292	Missense_Mutation	rs779594669	R1405H	0.2
UCEC	chr17	37097944	Missense_Mutation	novel	E2202D	0.3
UCEC	chr17	37221833	Nonsense_Mutation	novel	R1192*	0.3
UCEC	chr17	37149964	Missense_Mutation	novel	R1860Q	0.44
UCEC	chr17	37225008	Missense_Mutation	novel	C1153Y	0.23
UCEC	chr17	37243423	Missense_Mutation	novel	A960D	0.4
UCEC	chr17	37248150	Nonsense_Mutation	novel	R724*	0.2
UCEC	chr17	37259530	Missense_Mutation	novel	C444R	0.19
UCEC	chr17	37284920	Missense_Mutation	novel	K130T	0.05
UCEC	chr17	37097922	Missense_Mutation	novel	E2210K	0.36
UCEC	chr17	37248126	Missense_Mutation	novel	V732M	0.29
UCEC	chr17	37257749	Missense_Mutation	novel	F594L	0.34
UCEC	chr17	37161910	Silent	novel	S1740S	0.29
UCEC	chr17	37246949	Silent	novel	T779T	0.29
UCEC	chr17	37274260	Missense_Mutation	rs756880093	R314H	0.3
UCEC	chr17	37161801	Missense_Mutation	novel	D1777N	0.33
UCEC	chr17	37181206	Missense_Mutation	novel	R1643W	0.39
UCEC	chr17	37221833	Nonsense_Mutation	novel	R1192*	0.31
UCEC	chr17	37129368	Missense_Mutation	novel	P1981S	0.32
UCS	chr17	37283359	Missense_Mutation	novel	S173C	0.1

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
DLBC	DEL	0	0.18166
THCA	DEL	0.002	0.221
UCS	DEL	0.3929	0.19877
UVM	DEL	0.0375	0.22482

Survival Analysis

Cancer	P-value	Q-value
THYM	0.0034	Kaplan-Meier Survival Analysis
KIRC	0.0048	Kaplan-Meier Survival Analysis
SARC	0.0025	Kaplan-Meier Survival Analysis
MESO	0.0024	Kaplan-Meier Survival Analysis
ACC	0.003	Kaplan-Meier Survival Analysis
SKCM	0.01	Kaplan-Meier Survival Analysis
LUSC	0.04	Kaplan-Meier Survival Analysis
ESCA	0.033	Kaplan-Meier Survival Analysis
KIRP	0.044	Kaplan-Meier Survival Analysis
BLCA	0.032	Kaplan-Meier Survival Analysis
CESC	0.0062	Kaplan-Meier Survival Analysis
READ	0.0062	Kaplan-Meier Survival Analysis
KICH	0.0032	Kaplan-Meier Survival Analysis
LIHC	0.00042	Kaplan-Meier Survival Analysis
LGG	0.0004	Kaplan-Meier Survival Analysis
UVM	0.0002	Kaplan-Meier Survival Analysis
OV	0.0031	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Literatures

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Gene Ontology

Description

Ensembl ID: ENSG00000278540 (Gene tree)
Gene ID: 31
Gene Symbol: ACACA
Alias: ACC1|ACAC|ACC
Full Name: acetyl-CoA carboxylase alpha
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 321,835 bases
Position: chr17:37,084,988-37,406,822
Accession: 84
RBP type: non-canonical RBP
Summary: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
30209975	Thyroid hormone (T3) stimulates brown adipose tissue activation via mitochondrial biogenesis and MTOR-mediated mitophagy.	Autophagy	2019 Jan	Yau WW	doi: 10.1080/15548627.2018.1511263
25048402	Supplementation dietary zinc levels on growth performance, carcass traits, and intramuscular fat deposition in weaned piglets.	Biol Trace Elem Res	2014 Oct	Zhang HB	doi: 10.1007/s12011-014-0078-5
30891825	Arctigenin improves lipid metabolism by regulating AMP-activated protein kinase and downstream signaling pathways.	J Cell Biochem	2019 Aug	Song Y	doi: 10.1002/jcb.28602
19026012	Phosphatase and tensin homolog (PTEN) regulates hepatic lipogenesis, microsomal triglyceride transfer protein, and the secretion of apolipoprotein B-containing lipoproteins.	Hepatology	2008 Dec	Qiu W	doi: 10.1002/hep.22565.
31137884	Cyanidin-3-O-galactoside-enriched Aronia melanocarpa extract attenuates weight gain and adipogenic pathways in high-fat diet-induced obese C57BL/6 mice.	Nutrients	2019 May 27	Lim SM	doi: 10.3390/nu11051190.
31297058	Emodin Induced SREBP1-Dependent and SREBP1-Independent Apoptosis in Hepatocellular Carcinoma Cells.	Front Pharmacol	2019 Jun 25	Yang N	doi: 10.3389/fphar.2019.00709
12600843	Addition of inulin to a moderately high-carbohydrate diet reduces hepatic lipogenesis and plasma triacylglycerol concentrations in humans.	Am J Clin Nutr	2003 Mar	Letexier D	-
29230863	Characterization of a Nilaparvata lugens (Stl) brummer gene and analysis of its role in lipid metabolism.	Arch Insect Biochem Physiol	2018 Mar	Zhou J	doi: 10.1002/arch.21442

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000614333	ACACA-230	655	-	-	- (aa)	-	-
ENST00000619245	ACACA-244	635	-	-	- (aa)	-	-
ENST00000617649	ACACA-240	7912	XM_005257267	ENSP00000482368	2268 (aa)	XP_005257324	Q13085
ENST00000612926	ACACA-227	339	-	-	- (aa)	-	-
ENST00000612120	ACACA-225	566	-	-	- (aa)	-	-
ENST00000618053	ACACA-241	463	-	ENSP00000482064	96 (aa)	-	A0A087WYS8
ENST00000613776	ACACA-229	1372	-	-	- (aa)	-	-
ENST00000614438	ACACA-232	569	-	ENSP00000483852	112 (aa)	-	A0A087X126
ENST00000616352	ACACA-238	1626	-	ENSP00000477912	120 (aa)	-	A0A0C4DGT1
ENST00000612895	ACACA-226	9624	-	ENSP00000482269	2288 (aa)	-	Q13085
ENST00000615229	ACACA-236	1468	-	ENSP00000482498	114 (aa)	-	A0A087WYK6
ENST00000614450	ACACA-233	591	-	-	- (aa)	-	-
ENST00000614789	ACACA-235	662	-	ENSP00000479621	42 (aa)	-	A0A087WVR6
ENST00000618351	ACACA-242	716	-	-	- (aa)	-	-
ENST00000614482	ACACA-234	2177	-	ENSP00000480371	52 (aa)	-	A0A087WWN5
ENST00000619546	ACACA-245	5315	-	ENSP00000483969	998 (aa)	-	Q59FY4
ENST00000613146	ACACA-228	3974	-	-	- (aa)	-	-
ENST00000617548	ACACA-239	1063	-	ENSP00000481900	114 (aa)	-	A0A087WYK6
ENST00000614428	ACACA-231	9554	XM_011524703	ENSP00000478547	2346 (aa)	XP_011523005	Q13085
ENST00000618575	ACACA-243	772	-	-	- (aa)	-	-
ENST00000612007	ACACA-224	451	-	ENSP00000484948	84 (aa)	-	A0A087X2F8
ENST00000621960	ACACA-246	551	-	ENSP00000483696	94 (aa)	-	A0A087X0W4
ENST00000616317	ACACA-237	9961	XM_006721853	ENSP00000483300	2383 (aa)	XP_006721916	Q13085

Gene Model

Click here to download ENSG00000278540's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa00061	Fatty acid biosynthesis	KEGG
hsa00620	Pyruvate metabolism	KEGG
hsa00640	Propanoate metabolism	KEGG
hsa01100	Metabolic pathways	KEGG
hsa01212	Fatty acid metabolism	KEGG
hsa04152	AMPK signaling pathway	KEGG
hsa04910	Insulin signaling pathway	KEGG
hsa04922	Glucagon signaling pathway	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000278540	Body Mass Index	8.5299839548396E-5	17903300
ENSG00000278540	Body Mass Index	6.44217335813154E-5	17903300
ENSG00000278540	Body Mass Index	4.46497968306523E-5	17903300
ENSG00000278540	Body Mass Index	4.18538902585292E-5	17903300
ENSG00000278540	Body Mass Index	6.334248366624E-5	17903300
ENSG00000278540	Body Mass Index	3.85504303518931E-5	17903300
ENSG00000278540	Body Mass Index	6.3610680108404E-5	17903300
ENSG00000278540	Body Mass Index	7.12717198981484E-5	17903300
ENSG00000278540	Body Mass Index	6.38799512154111E-5	17903300
ENSG00000278540	Child Development Disorders, Pervasive	5.5000000E-005	-
ENSG00000278540	Celiac Disease	8E-7	24999842

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000278540	rs182210624	17	37159111	G	Macrophage inflammatory protein 1b levels	27989323	[0.17-0.37] SD units increase	0.2695	EFO_0008219
ENSG00000278540	rs185128671	17	37365406	G	Macrophage inflammatory protein 1b levels	27989323	[0.42-0.8] SD units increase	0.6071	EFO_0008219
ENSG00000278540	rs9906044	17	37251740	?	Body mass index	30595370			EFO_0004340

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000278540's network

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001650	fibrillar center	-	IDA	Component
GO:0001894	tissue homeostasis	-	IEA	Process
GO:0003989	acetyl-CoA carboxylase activity	20952656.	ISS	Function
GO:0003989	acetyl-CoA carboxylase activity	-	TAS	Function
GO:0004075	biotin carboxylase activity	-	IEA	Function
GO:0005515	protein binding	16326698.16794074.18056116.19343720.20457939.20952656.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005829	cytosol	-	IDA	Component
GO:0005829	cytosol	-	ISS	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006084	acetyl-CoA metabolic process	-	ISS	Process
GO:0006633	fatty acid biosynthetic process	-	ISS	Process
GO:0006853	carnitine shuttle	-	TAS	Process
GO:0015629	actin cytoskeleton	-	IDA	Component
GO:0019538	protein metabolic process	-	IEA	Process
GO:0031325	positive regulation of cellular metabolic process	-	TAS	Process
GO:0042802	identical protein binding	20457939.	IPI	Function
GO:0045540	regulation of cholesterol biosynthetic process	-	TAS	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:0046949	fatty-acyl-CoA biosynthetic process	-	TAS	Process
GO:0051289	protein homotetramerization	20952656.	ISS	Process
GO:0055088	lipid homeostasis	-	IEA	Process
GO:0071380	cellular response to prostaglandin E stimulus	-	IEA	Process
GO:2001295	malonyl-CoA biosynthetic process	-	IEA	Process

EuRBPDB

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Description

RBPome

Literatures

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Gene Ontology

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