EuRBPDB

Description

RBDs

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSDARG00000008472 (Gene tree)
Gene ID: 393115
Gene Symbol: apex2
Alias: zgc:55889
Full Name: APEX nuclease (apurinic/apyrimidinic endonuclease) 2
Gene Type: protein_coding
Species: Danio_rerio
Status: putative
Strand: Minus strand
Length: 5535 bases
Position: chr8:22509508-22515042
Accession: ZDB-GENE-040426-835
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSDARP00000021896	Exo_endo_phos	PF03372.23	2.6e-17	1	1
ENSDARP00000149485	Exo_endo_phos	PF03372.23	1.7e-08	1	1

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSDART00000189272	-	3390	-	ENSDARP00000149485	545 (aa)	-	A0A2R8QCQ7
ENSDART00000021514	-	1852	-	ENSDARP00000021896	558 (aa)	-	F1Q865

Gene Model

Click here to download ENSDARG00000008472's gene model file

Pathways

Pathway ID	Pathway Name	Source
dre03410	Base excision repair	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSDARG00000008472's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSDARG00000008472	apex2	99	45.503	ENSG00000169188	APEX2	99	44.930	Homo_sapiens
ENSDARG00000008472	apex2	100	63.204	ENSAPOG00000005805	apex2	100	63.204	Acanthochromis_polyacanthus
ENSDARG00000008472	apex2	99	45.150	ENSAMEG00000003608	APEX2	99	44.974	Ailuropoda_melanoleuca
ENSDARG00000008472	apex2	100	60.000	ENSACIG00000010000	apex2	100	60.494	Amphilophus_citrinellus
ENSDARG00000008472	apex2	100	63.204	ENSAOCG00000021774	apex2	100	63.204	Amphiprion_ocellaris
ENSDARG00000008472	apex2	100	63.204	ENSAPEG00000020890	apex2	94	63.204	Amphiprion_percula
ENSDARG00000008472	apex2	100	61.207	ENSATEG00000023600	apex2	100	61.207	Anabas_testudineus
ENSDARG00000008472	apex2	99	46.085	ENSACAG00000011201	APEX2	99	45.893	Anolis_carolinensis
ENSDARG00000008472	apex2	97	39.928	ENSANAG00000020845	-	99	39.568	Aotus_nancymaae
ENSDARG00000008472	apex2	99	46.316	ENSANAG00000021907	-	99	45.614	Aotus_nancymaae
ENSDARG00000008472	apex2	100	65.371	ENSAMXG00000007422	apex2	100	65.371	Astyanax_mexicanus
ENSDARG00000008472	apex2	99	47.100	ENSBTAG00000013177	APEX2	99	46.397	Bos_taurus
ENSDARG00000008472	apex2	99	45.965	ENSCJAG00000016584	APEX2	99	45.789	Callithrix_jacchus
ENSDARG00000008472	apex2	99	44.367	ENSCAFG00000014310	APEX2	99	43.902	Canis_familiaris
ENSDARG00000008472	apex2	99	45.234	ENSCAFG00020013818	APEX2	93	57.589	Canis_lupus_dingo
ENSDARG00000008472	apex2	99	46.573	ENSCHIG00000019916	APEX2	99	46.573	Capra_hircus
ENSDARG00000008472	apex2	99	46.316	ENSTSYG00000005612	APEX2	99	46.140	Carlito_syrichta
ENSDARG00000008472	apex2	99	43.739	ENSCPOG00000007265	APEX2	99	43.386	Cavia_porcellus
ENSDARG00000008472	apex2	96	39.926	ENSCCAG00000025405	-	96	40.111	Cebus_capucinus
ENSDARG00000008472	apex2	99	44.948	ENSCATG00000044854	APEX2	99	44.948	Cercocebus_atys
ENSDARG00000008472	apex2	99	45.326	ENSCLAG00000017315	APEX2	99	45.150	Chinchilla_lanigera
ENSDARG00000008472	apex2	99	45.122	ENSCSAG00000012124	APEX2	99	45.122	Chlorocebus_sabaeus
ENSDARG00000008472	apex2	100	45.552	ENSCPBG00000016631	APEX2	99	45.907	Chrysemys_picta_bellii
ENSDARG00000008472	apex2	85	56.757	ENSCSAVG00000006052	-	97	56.757	Ciona_savignyi
ENSDARG00000008472	apex2	99	44.640	ENSCANG00000003053	APEX2	99	44.640	Colobus_angolensis_palliatus
ENSDARG00000008472	apex2	99	46.466	ENSCGRG00001008132	Apex2	99	45.936	Cricetulus_griseus_chok1gshd
ENSDARG00000008472	apex2	99	46.466	ENSCGRG00000009667	Apex2	89	58.986	Cricetulus_griseus_crigri
ENSDARG00000008472	apex2	100	57.895	ENSCSEG00000019900	apex2	99	57.385	Cynoglossus_semilaevis
ENSDARG00000008472	apex2	100	60.622	ENSCVAG00000021583	apex2	100	60.622	Cyprinodon_variegatus
ENSDARG00000008472	apex2	99	45.088	ENSDNOG00000038901	APEX2	99	45.088	Dasypus_novemcinctus
ENSDARG00000008472	apex2	74	64.615	ENSEBUG00000015654	apex2	85	64.615	Eptatretus_burgeri
ENSDARG00000008472	apex2	99	46.046	ENSEASG00005011694	APEX2	90	45.870	Equus_asinus_asinus
ENSDARG00000008472	apex2	99	46.046	ENSECAG00000026921	APEX2	90	45.870	Equus_caballus
ENSDARG00000008472	apex2	99	46.479	ENSEEUG00000013172	APEX2	99	46.479	Erinaceus_europaeus
ENSDARG00000008472	apex2	100	60.720	ENSELUG00000021417	apex2	99	60.720	Esox_lucius
ENSDARG00000008472	apex2	99	45.439	ENSFCAG00000021990	APEX2	99	45.263	Felis_catus
ENSDARG00000008472	apex2	99	44.815	ENSFDAG00000008076	APEX2	90	59.434	Fukomys_damarensis
ENSDARG00000008472	apex2	100	56.437	ENSFHEG00000021411	apex2	99	55.594	Fundulus_heteroclitus
ENSDARG00000008472	apex2	67	73.889	ENSGMOG00000019681	apex2	100	71.505	Gadus_morhua
ENSDARG00000008472	apex2	100	59.794	ENSGAFG00000005829	apex2	100	60.000	Gambusia_affinis
ENSDARG00000008472	apex2	65	78.857	ENSGACG00000012307	apex2	92	77.095	Gasterosteus_aculeatus
ENSDARG00000008472	apex2	92	43.580	ENSGAGG00000011520	APEX2	88	43.327	Gopherus_agassizii
ENSDARG00000008472	apex2	99	45.217	ENSGGOG00000002056	APEX2	99	45.043	Gorilla_gorilla
ENSDARG00000008472	apex2	100	62.007	ENSHBUG00000009938	apex2	100	62.500	Haplochromis_burtoni
ENSDARG00000008472	apex2	99	44.815	ENSHGLG00000000273	APEX2	99	54.077	Heterocephalus_glaber_female
ENSDARG00000008472	apex2	100	60.714	ENSHCOG00000010165	apex2	100	60.714	Hippocampus_comes
ENSDARG00000008472	apex2	100	63.497	ENSIPUG00000000352	APEX2	100	63.452	Ictalurus_punctatus
ENSDARG00000008472	apex2	99	46.914	ENSSTOG00000025121	APEX2	85	62.500	Ictidomys_tridecemlineatus
ENSDARG00000008472	apex2	99	46.749	ENSJJAG00000019611	Apex2	93	61.215	Jaculus_jaculus
ENSDARG00000008472	apex2	100	61.170	ENSKMAG00000006985	apex2	100	61.170	Kryptolebias_marmoratus
ENSDARG00000008472	apex2	100	61.073	ENSLBEG00000012139	apex2	100	61.073	Labrus_bergylta
ENSDARG00000008472	apex2	100	51.053	ENSLACG00000000865	APEX2	100	50.791	Latimeria_chalumnae
ENSDARG00000008472	apex2	100	57.692	ENSLOCG00000014467	apex2	100	58.333	Lepisosteus_oculatus
ENSDARG00000008472	apex2	99	44.894	ENSLAFG00000018312	APEX2	99	44.542	Loxodonta_africana
ENSDARG00000008472	apex2	99	45.503	ENSMFAG00000002486	APEX2	99	45.503	Macaca_fascicularis
ENSDARG00000008472	apex2	99	45.503	ENSMMUG00000008428	APEX2	99	45.503	Macaca_mulatta
ENSDARG00000008472	apex2	99	45.326	ENSMNEG00000036783	APEX2	99	45.326	Macaca_nemestrina
ENSDARG00000008472	apex2	99	44.948	ENSMLEG00000028208	APEX2	99	44.948	Mandrillus_leucophaeus
ENSDARG00000008472	apex2	100	61.644	ENSMAMG00000024220	apex2	100	61.644	Mastacembelus_armatus
ENSDARG00000008472	apex2	100	61.649	ENSMZEG00005026322	apex2	100	62.143	Maylandia_zebra
ENSDARG00000008472	apex2	99	43.860	ENSMICG00000043181	APEX2	99	43.333	Microcebus_murinus
ENSDARG00000008472	apex2	99	45.679	ENSMOCG00000004339	Apex2	91	58.986	Microtus_ochrogaster
ENSDARG00000008472	apex2	100	60.140	ENSMMOG00000017340	apex2	100	60.315	Mola_mola
ENSDARG00000008472	apex2	99	49.462	ENSMODG00000005341	APEX2	82	75.806	Monodelphis_domestica
ENSDARG00000008472	apex2	100	58.844	ENSMALG00000014179	apex2	100	58.814	Monopterus_albus
ENSDARG00000008472	apex2	99	46.113	MGP_CAROLIEiJ_G0033484	Apex2	100	53.763	Mus_caroli
ENSDARG00000008472	apex2	99	45.518	ENSMUSG00000025269	Apex2	99	53.405	Mus_musculus
ENSDARG00000008472	apex2	99	46.303	MGP_PahariEiJ_G0032023	Apex2	100	54.122	Mus_pahari
ENSDARG00000008472	apex2	99	45.694	MGP_SPRETEiJ_G0034654	Apex2	100	53.763	Mus_spretus
ENSDARG00000008472	apex2	99	45.026	ENSMPUG00000003293	APEX2	99	45.407	Mustela_putorius_furo
ENSDARG00000008472	apex2	99	46.737	ENSMLUG00000016298	-	99	46.384	Myotis_lucifugus
ENSDARG00000008472	apex2	99	45.922	ENSMLUG00000004562	-	99	45.053	Myotis_lucifugus
ENSDARG00000008472	apex2	99	46.032	ENSNGAG00000013576	Apex2	99	45.150	Nannospalax_galili
ENSDARG00000008472	apex2	100	61.307	ENSNBRG00000010099	apex2	100	61.796	Neolamprologus_brichardi
ENSDARG00000008472	apex2	56	66.129	ENSNLEG00000032067	-	75	66.129	Nomascus_leucogenys
ENSDARG00000008472	apex2	100	61.620	ENSONIG00000016881	apex2	100	61.620	Oreochromis_niloticus
ENSDARG00000008472	apex2	95	53.831	ENSOANG00000000689	-	96	54.215	Ornithorhynchus_anatinus
ENSDARG00000008472	apex2	81	59.906	ENSOCUG00000000570	APEX2	82	59.906	Oryctolagus_cuniculus
ENSDARG00000008472	apex2	100	59.965	ENSORLG00000014053	apex2	100	59.965	Oryzias_latipes
ENSDARG00000008472	apex2	100	59.649	ENSORLG00020013253	apex2	100	59.649	Oryzias_latipes_hni
ENSDARG00000008472	apex2	100	59.441	ENSORLG00015007515	apex2	100	59.441	Oryzias_latipes_hsok
ENSDARG00000008472	apex2	100	58.772	ENSOMEG00000003655	apex2	100	58.772	Oryzias_melastigma
ENSDARG00000008472	apex2	99	46.573	ENSOGAG00000007797	APEX2	99	45.951	Otolemur_garnettii
ENSDARG00000008472	apex2	99	46.573	ENSOARG00000005742	APEX2	99	46.573	Ovis_aries
ENSDARG00000008472	apex2	99	45.105	ENSPPAG00000035747	APEX2	99	44.930	Pan_paniscus
ENSDARG00000008472	apex2	99	45.679	ENSPPRG00000002440	APEX2	99	45.503	Panthera_pardus
ENSDARG00000008472	apex2	99	45.679	ENSPTIG00000021651	APEX2	99	45.503	Panthera_tigris_altaica
ENSDARG00000008472	apex2	99	45.105	ENSPTRG00000021946	APEX2	99	44.930	Pan_troglodytes
ENSDARG00000008472	apex2	99	44.948	ENSPANG00000003595	APEX2	99	44.948	Papio_anubis
ENSDARG00000008472	apex2	100	59.266	ENSPKIG00000007752	apex2	100	59.965	Paramormyrops_kingsleyae
ENSDARG00000008472	apex2	100	62.500	ENSPMGG00000009151	apex2	100	61.620	Periophthalmus_magnuspinnatus
ENSDARG00000008472	apex2	99	45.518	ENSPEMG00000016475	Apex2	89	58.257	Peromyscus_maniculatus_bairdii
ENSDARG00000008472	apex2	75	74.603	ENSPCIG00000007633	APEX2	85	74.603	Phascolarctos_cinereus
ENSDARG00000008472	apex2	100	61.207	ENSPFOG00000000408	apex2	100	61.207	Poecilia_formosa
ENSDARG00000008472	apex2	100	60.862	ENSPLAG00000023814	apex2	100	60.862	Poecilia_latipinna
ENSDARG00000008472	apex2	100	61.512	ENSPMEG00000023222	apex2	100	61.512	Poecilia_mexicana
ENSDARG00000008472	apex2	99	44.870	ENSPPYG00000020388	APEX2	99	44.696	Pongo_abelii
ENSDARG00000008472	apex2	99	46.316	ENSPCOG00000016083	APEX2	99	46.140	Propithecus_coquereli
ENSDARG00000008472	apex2	94	46.318	ENSPVAG00000007851	APEX2	99	45.930	Pteropus_vampyrus
ENSDARG00000008472	apex2	100	60.417	ENSPNYG00000015698	apex2	100	60.900	Pundamilia_nyererei
ENSDARG00000008472	apex2	100	65.247	ENSPNAG00000011666	apex2	100	65.247	Pygocentrus_nattereri
ENSDARG00000008472	apex2	99	46.303	ENSRNOG00000000166	Apex2	99	46.303	Rattus_norvegicus
ENSDARG00000008472	apex2	99	44.599	ENSRBIG00000036500	APEX2	99	44.599	Rhinopithecus_bieti
ENSDARG00000008472	apex2	99	44.599	ENSRROG00000032674	APEX2	99	44.599	Rhinopithecus_roxellana
ENSDARG00000008472	apex2	65	43.137	YBL019W	APN2	76	43.137	Saccharomyces_cerevisiae
ENSDARG00000008472	apex2	99	45.167	ENSSBOG00000030500	-	99	45.263	Saimiri_boliviensis_boliviensis
ENSDARG00000008472	apex2	96	38.547	ENSSBOG00000003489	-	96	37.989	Saimiri_boliviensis_boliviensis
ENSDARG00000008472	apex2	99	50.626	ENSSHAG00000007846	APEX2	99	50.805	Sarcophilus_harrisii
ENSDARG00000008472	apex2	100	61.607	ENSSFOG00015010354	apex2	100	62.032	Scleropages_formosus
ENSDARG00000008472	apex2	100	61.796	ENSSMAG00000012753	apex2	100	62.214	Scophthalmus_maximus
ENSDARG00000008472	apex2	100	63.540	ENSSDUG00000022892	apex2	100	64.021	Seriola_dumerili
ENSDARG00000008472	apex2	100	62.857	ENSSLDG00000024347	apex2	100	63.167	Seriola_lalandi_dorsalis
ENSDARG00000008472	apex2	99	45.184	ENSSARG00000010297	APEX2	99	45.884	Sorex_araneus
ENSDARG00000008472	apex2	100	61.905	ENSSPAG00000016279	apex2	100	61.905	Stegastes_partitus
ENSDARG00000008472	apex2	99	47.443	ENSSSCG00000012348	-	99	47.090	Sus_scrofa
ENSDARG00000008472	apex2	100	61.053	ENSTRUG00000015660	apex2	100	61.053	Takifugu_rubripes
ENSDARG00000008472	apex2	87	56.879	ENSTNIG00000003725	apex2	100	56.879	Tetraodon_nigroviridis
ENSDARG00000008472	apex2	94	44.272	ENSTBEG00000010520	APEX2	99	44.078	Tupaia_belangeri
ENSDARG00000008472	apex2	99	45.679	ENSUAMG00000004720	APEX2	93	57.589	Ursus_americanus
ENSDARG00000008472	apex2	99	43.463	ENSUMAG00000002892	APEX2	99	42.933	Ursus_maritimus
ENSDARG00000008472	apex2	99	45.088	ENSVVUG00000005989	APEX2	99	44.251	Vulpes_vulpes
ENSDARG00000008472	apex2	99	50.089	ENSXETG00000022026	apex2	99	49.911	Xenopus_tropicalis
ENSDARG00000008472	apex2	100	61.340	ENSXMAG00000025740	apex2	100	61.340	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003677	DNA binding	-	IEA	Function
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	21873635.	IBA	Function
GO:0004518	nuclease activity	-	IEA	Function
GO:0004519	endonuclease activity	-	IEA	Function
GO:0004528	phosphodiesterase I activity	21873635.	IBA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	-	IEA	Component
GO:0005737	cytoplasm	-	IEA	Component
GO:0005739	mitochondrion	-	IEA	Component
GO:0006281	DNA repair	-	IEA	Process
GO:0006284	base-excision repair	21873635.	IBA	Process
GO:0006974	cellular response to DNA damage stimulus	-	IEA	Process
GO:0008270	zinc ion binding	-	IEA	Function
GO:0008311	double-stranded DNA 3'-5' exodeoxyribonuclease activity	21873635.	IBA	Function
GO:0016787	hydrolase activity	-	IEA	Function
GO:0016829	lyase activity	-	IEA	Function
GO:0046872	metal ion binding	-	IEA	Function
GO:0140078	class I DNA-(apurinic or apyrimidinic site) endonuclease activity	-	IEA	Function