EuRBPDB

Description

RBDs

Transcripts

Gene Model

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSDARG00000035954 (Gene tree)
Gene ID: 553516
Gene Symbol: tdp2b
Alias: tdp2|ttrap|ttrapl
Full Name: tyrosyl-DNA phosphodiesterase 2b
Gene Type: protein_coding
Species: Danio_rerio
Status: putative
Strand: Minus strand
Length: 7330 bases
Position: chr19:31568992-31576321
Accession: ZDB-GENE-050816-1
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSDARP00000094388	Exo_endo_phos	PF03372.23	1.2e-08	1	1

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSDART00000103612	-	1727	-	ENSDARP00000094388	383 (aa)	-	Z4YI19

Gene Model

Click here to download ENSDARG00000035954's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSDARG00000035954's network

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSDARG00000035954	tdp2b	70	53.532	ENSDARG00000069941	tdp2a	59	53.532

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSDARG00000035954	tdp2b	94	51.648	ENSG00000111802	TDP2	92	55.017	Homo_sapiens
ENSDARG00000035954	tdp2b	66	59.144	ENSAPOG00000018379	-	90	59.144	Acanthochromis_polyacanthus
ENSDARG00000035954	tdp2b	73	54.448	ENSAMEG00000010230	TDP2	99	54.448	Ailuropoda_melanoleuca
ENSDARG00000035954	tdp2b	68	57.414	ENSAPEG00000004208	-	94	57.414	Amphiprion_percula
ENSDARG00000035954	tdp2b	77	53.020	ENSATEG00000010663	-	94	53.020	Anabas_testudineus
ENSDARG00000035954	tdp2b	94	52.778	ENSACAG00000002332	TDP2	96	50.660	Anolis_carolinensis
ENSDARG00000035954	tdp2b	94	52.473	ENSANAG00000020033	TDP2	93	52.473	Aotus_nancymaae
ENSDARG00000035954	tdp2b	74	61.268	ENSACLG00000016132	tdp2b	94	61.268	Astatotilapia_calliptera
ENSDARG00000035954	tdp2b	74	61.972	ENSACLG00000016174	tdp2b	94	61.972	Astatotilapia_calliptera
ENSDARG00000035954	tdp2b	66	67.323	ENSACLG00000016148	tdp2b	90	67.323	Astatotilapia_calliptera
ENSDARG00000035954	tdp2b	97	68.490	ENSAMXG00000011775	tdp2b	99	68.490	Astyanax_mexicanus
ENSDARG00000035954	tdp2b	69	50.000	ENSAMXG00000036549	tdp2a	87	50.000	Astyanax_mexicanus
ENSDARG00000035954	tdp2b	95	51.381	ENSBTAG00000000365	TDP2	93	51.381	Bos_taurus
ENSDARG00000035954	tdp2b	94	52.198	ENSCJAG00000021963	-	93	52.198	Callithrix_jacchus
ENSDARG00000035954	tdp2b	94	53.022	ENSCJAG00000006074	TDP2	91	56.491	Callithrix_jacchus
ENSDARG00000035954	tdp2b	95	51.639	ENSCAFG00000010428	TDP2	95	56.338	Canis_familiaris
ENSDARG00000035954	tdp2b	73	56.338	ENSCAFG00020009994	TDP2	95	56.338	Canis_lupus_dingo
ENSDARG00000035954	tdp2b	73	56.786	ENSCHIG00000015294	-	94	56.786	Capra_hircus
ENSDARG00000035954	tdp2b	87	50.448	ENSTSYG00000037199	TDP2	99	51.351	Carlito_syrichta
ENSDARG00000035954	tdp2b	95	52.877	ENSCPOG00000006390	TDP2	99	51.697	Cavia_porcellus
ENSDARG00000035954	tdp2b	94	52.747	ENSCCAG00000022734	TDP2	90	56.537	Cebus_capucinus
ENSDARG00000035954	tdp2b	95	51.639	ENSCATG00000022076	TDP2	90	55.830	Cercocebus_atys
ENSDARG00000035954	tdp2b	95	52.603	ENSCLAG00000002072	TDP2	94	52.603	Chinchilla_lanigera
ENSDARG00000035954	tdp2b	94	51.923	ENSCSAG00000007769	TDP2	94	51.923	Chlorocebus_sabaeus
ENSDARG00000035954	tdp2b	96	51.499	ENSCPBG00000006551	TDP2	91	50.131	Chrysemys_picta_bellii
ENSDARG00000035954	tdp2b	94	51.374	ENSCANG00000040122	TDP2	91	55.477	Colobus_angolensis_palliatus
ENSDARG00000035954	tdp2b	95	45.055	ENSCGRG00001000384	Tdp2	93	43.467	Cricetulus_griseus_chok1gshd
ENSDARG00000035954	tdp2b	95	43.956	ENSCGRG00000010250	Tdp2	96	42.480	Cricetulus_griseus_crigri
ENSDARG00000035954	tdp2b	98	63.926	ENSCVAG00000003114	tdp2b	98	64.191	Cyprinodon_variegatus
ENSDARG00000035954	tdp2b	95	51.359	ENSDNOG00000044082	TDP2	93	51.359	Dasypus_novemcinctus
ENSDARG00000035954	tdp2b	73	55.872	ENSETEG00000019096	TDP2	99	55.872	Echinops_telfairi
ENSDARG00000035954	tdp2b	92	36.408	ENSEBUG00000006535	tdp2a	96	36.408	Eptatretus_burgeri
ENSDARG00000035954	tdp2b	95	53.039	ENSEASG00005007656	TDP2	93	53.039	Equus_asinus_asinus
ENSDARG00000035954	tdp2b	95	53.315	ENSECAG00000014264	TDP2	93	53.315	Equus_caballus
ENSDARG00000035954	tdp2b	94	52.632	ENSEEUG00000010776	TDP2	92	52.632	Erinaceus_europaeus
ENSDARG00000035954	tdp2b	96	63.613	ENSELUG00000016449	tdp2b	97	63.613	Esox_lucius
ENSDARG00000035954	tdp2b	78	44.333	ENSELUG00000009321	tdp2a	79	49.213	Esox_lucius
ENSDARG00000035954	tdp2b	95	52.055	ENSFCAG00000025612	TDP2	93	52.055	Felis_catus
ENSDARG00000035954	tdp2b	96	47.541	ENSFALG00000004710	TDP2	94	48.361	Ficedula_albicollis
ENSDARG00000035954	tdp2b	73	56.228	ENSFDAG00000006512	TDP2	95	56.228	Fukomys_damarensis
ENSDARG00000035954	tdp2b	68	53.506	ENSFHEG00000013560	-	92	53.506	Fundulus_heteroclitus
ENSDARG00000035954	tdp2b	96	48.907	ENSGALG00000013637	TDP2	92	50.000	Gallus_gallus
ENSDARG00000035954	tdp2b	96	52.044	ENSGAGG00000002853	TDP2	87	52.044	Gopherus_agassizii
ENSDARG00000035954	tdp2b	94	51.648	ENSGGOG00000014237	TDP2	93	54.795	Gorilla_gorilla
ENSDARG00000035954	tdp2b	52	68.182	ENSHBUG00000005421	-	82	68.182	Haplochromis_burtoni
ENSDARG00000035954	tdp2b	96	65.405	ENSHBUG00000002714	tdp2b	96	65.405	Haplochromis_burtoni
ENSDARG00000035954	tdp2b	95	51.374	ENSHGLG00000008655	TDP2	94	51.374	Heterocephalus_glaber_female
ENSDARG00000035954	tdp2b	95	51.374	ENSHGLG00100019087	TDP2	94	51.374	Heterocephalus_glaber_male
ENSDARG00000035954	tdp2b	96	68.817	ENSIPUG00000013691	tdp2b	97	68.817	Ictalurus_punctatus
ENSDARG00000035954	tdp2b	97	46.381	ENSJJAG00000021685	Tdp2	97	46.381	Jaculus_jaculus
ENSDARG00000035954	tdp2b	67	57.308	ENSKMAG00000015485	-	83	57.308	Kryptolebias_marmoratus
ENSDARG00000035954	tdp2b	96	53.406	ENSLACG00000008852	TDP2	95	53.406	Latimeria_chalumnae
ENSDARG00000035954	tdp2b	73	62.989	ENSLOCG00000005817	tdp2b	98	62.989	Lepisosteus_oculatus
ENSDARG00000035954	tdp2b	94	51.099	ENSLAFG00000002567	TDP2	95	51.099	Loxodonta_africana
ENSDARG00000035954	tdp2b	95	51.781	ENSMFAG00000045296	TDP2	91	55.634	Macaca_fascicularis
ENSDARG00000035954	tdp2b	95	51.781	ENSMMUG00000009803	TDP2	94	51.781	Macaca_mulatta
ENSDARG00000035954	tdp2b	95	51.781	ENSMNEG00000038003	TDP2	91	55.634	Macaca_nemestrina
ENSDARG00000035954	tdp2b	94	51.923	ENSMLEG00000028883	TDP2	94	51.923	Mandrillus_leucophaeus
ENSDARG00000035954	tdp2b	95	65.753	ENSMAMG00000013654	tdp2b	95	65.753	Mastacembelus_armatus
ENSDARG00000035954	tdp2b	74	61.972	ENSMZEG00005004126	tdp2b	94	61.972	Maylandia_zebra
ENSDARG00000035954	tdp2b	64	58.130	ENSMZEG00005003980	-	78	58.130	Maylandia_zebra
ENSDARG00000035954	tdp2b	69	64.552	ENSMZEG00005004077	tdp2b	91	64.552	Maylandia_zebra
ENSDARG00000035954	tdp2b	66	61.176	ENSMZEG00005004103	tdp2b	85	61.176	Maylandia_zebra
ENSDARG00000035954	tdp2b	69	63.534	ENSMZEG00005004153	tdp2b	94	63.534	Maylandia_zebra
ENSDARG00000035954	tdp2b	96	63.342	ENSMZEG00005003950	tdp2b	96	63.342	Maylandia_zebra
ENSDARG00000035954	tdp2b	64	64.516	ENSMZEG00005004055	tdp2b	82	64.516	Maylandia_zebra
ENSDARG00000035954	tdp2b	96	48.634	ENSMGAG00000008014	TDP2	91	49.180	Meleagris_gallopavo
ENSDARG00000035954	tdp2b	95	46.703	ENSMAUG00000014451	Tdp2	93	45.333	Mesocricetus_auratus
ENSDARG00000035954	tdp2b	95	52.893	ENSMICG00000000039	TDP2	94	56.890	Microcebus_murinus
ENSDARG00000035954	tdp2b	95	46.429	ENSMOCG00000002823	Tdp2	94	44.709	Microtus_ochrogaster
ENSDARG00000035954	tdp2b	85	54.268	ENSMODG00000011653	TDP2	94	54.573	Monodelphis_domestica
ENSDARG00000035954	tdp2b	65	58.730	ENSMALG00000005368	-	85	58.730	Monopterus_albus
ENSDARG00000035954	tdp2b	95	48.626	MGP_CAROLIEiJ_G0018354	Tdp2	90	48.626	Mus_caroli
ENSDARG00000035954	tdp2b	95	47.802	ENSMUSG00000035958	Tdp2	90	47.802	Mus_musculus
ENSDARG00000035954	tdp2b	94	46.006	MGP_PahariEiJ_G0019417	Tdp2	90	46.006	Mus_pahari
ENSDARG00000035954	tdp2b	95	47.802	MGP_SPRETEiJ_G0019220	Tdp2	90	47.802	Mus_spretus
ENSDARG00000035954	tdp2b	95	52.210	ENSMPUG00000004516	TDP2	94	52.210	Mustela_putorius_furo
ENSDARG00000035954	tdp2b	94	48.209	ENSMLUG00000013506	TDP2	93	48.485	Myotis_lucifugus
ENSDARG00000035954	tdp2b	93	45.902	ENSNGAG00000001375	Tdp2	90	45.902	Nannospalax_galili
ENSDARG00000035954	tdp2b	94	51.923	ENSNLEG00000002447	TDP2	94	51.923	Nomascus_leucogenys
ENSDARG00000035954	tdp2b	95	53.168	ENSOPRG00000016299	TDP2	96	53.168	Ochotona_princeps
ENSDARG00000035954	tdp2b	73	56.338	ENSODEG00000014018	TDP2	94	56.338	Octodon_degus
ENSDARG00000035954	tdp2b	94	52.198	ENSOCUG00000013773	TDP2	93	52.198	Oryctolagus_cuniculus
ENSDARG00000035954	tdp2b	66	56.202	ENSORLG00000001661	-	94	56.202	Oryzias_latipes
ENSDARG00000035954	tdp2b	73	53.004	ENSORLG00020004634	-	94	56.202	Oryzias_latipes_hni
ENSDARG00000035954	tdp2b	66	48.425	ENSORLG00015008190	-	92	48.425	Oryzias_latipes_hsok
ENSDARG00000035954	tdp2b	71	52.015	ENSOMEG00000015899	-	93	52.381	Oryzias_melastigma
ENSDARG00000035954	tdp2b	94	51.374	ENSOGAG00000025303	TDP2	91	51.374	Otolemur_garnettii
ENSDARG00000035954	tdp2b	95	51.507	ENSPPAG00000029023	TDP2	94	54.608	Pan_paniscus
ENSDARG00000035954	tdp2b	95	51.507	ENSPPRG00000015398	TDP2	93	51.507	Panthera_pardus
ENSDARG00000035954	tdp2b	73	55.477	ENSPTIG00000018574	TDP2	94	55.477	Panthera_tigris_altaica
ENSDARG00000035954	tdp2b	95	51.507	ENSPTRG00000017778	TDP2	93	54.608	Pan_troglodytes
ENSDARG00000035954	tdp2b	95	50.964	ENSPANG00000017590	TDP2	90	56.537	Papio_anubis
ENSDARG00000035954	tdp2b	96	64.151	ENSPKIG00000006483	tdp2b	96	64.151	Paramormyrops_kingsleyae
ENSDARG00000035954	tdp2b	73	55.872	ENSPSIG00000004948	TDP2	95	55.872	Pelodiscus_sinensis
ENSDARG00000035954	tdp2b	94	47.383	ENSPEMG00000001788	Tdp2	90	47.253	Peromyscus_maniculatus_bairdii
ENSDARG00000035954	tdp2b	67	43.173	ENSPMAG00000001570	tdp2b	99	43.542	Petromyzon_marinus
ENSDARG00000035954	tdp2b	95	51.923	ENSPCIG00000007316	TDP2	92	50.663	Phascolarctos_cinereus
ENSDARG00000035954	tdp2b	70	52.963	ENSPFOG00000017990	-	97	52.963	Poecilia_formosa
ENSDARG00000035954	tdp2b	72	52.158	ENSPLAG00000019439	-	83	52.158	Poecilia_latipinna
ENSDARG00000035954	tdp2b	72	51.264	ENSPMEG00000010824	-	93	51.264	Poecilia_mexicana
ENSDARG00000035954	tdp2b	95	51.093	ENSPPYG00000016282	TDP2	85	51.374	Pongo_abelii
ENSDARG00000035954	tdp2b	95	51.381	ENSPCOG00000021415	TDP2	97	55.160	Propithecus_coquereli
ENSDARG00000035954	tdp2b	60	47.619	ENSPNYG00000001944	-	75	56.354	Pundamilia_nyererei
ENSDARG00000035954	tdp2b	69	59.929	ENSPNYG00000011504	tdp2b	92	59.929	Pundamilia_nyererei
ENSDARG00000035954	tdp2b	96	62.973	ENSPNYG00000011532	tdp2b	96	62.973	Pundamilia_nyererei
ENSDARG00000035954	tdp2b	69	54.753	ENSPNAG00000022162	tdp2a	67	54.753	Pygocentrus_nattereri
ENSDARG00000035954	tdp2b	92	47.887	ENSRNOG00000018246	Tdp2	89	47.887	Rattus_norvegicus
ENSDARG00000035954	tdp2b	94	51.374	ENSRBIG00000037119	TDP2	91	55.477	Rhinopithecus_bieti
ENSDARG00000035954	tdp2b	95	51.093	ENSRROG00000005025	TDP2	91	55.477	Rhinopithecus_roxellana
ENSDARG00000035954	tdp2b	95	52.055	ENSSBOG00000028734	TDP2	91	55.634	Saimiri_boliviensis_boliviensis
ENSDARG00000035954	tdp2b	95	52.762	ENSSHAG00000002506	TDP2	90	52.762	Sarcophilus_harrisii
ENSDARG00000035954	tdp2b	66	55.691	ENSSFOG00015011322	-	71	55.556	Scleropages_formosus
ENSDARG00000035954	tdp2b	73	53.684	ENSSARG00000013547	TDP2	99	53.684	Sorex_araneus
ENSDARG00000035954	tdp2b	96	50.681	ENSSPUG00000008288	TDP2	97	50.267	Sphenodon_punctatus
ENSDARG00000035954	tdp2b	95	51.499	ENSSSCG00000001092	TDP2	93	51.499	Sus_scrofa
ENSDARG00000035954	tdp2b	66	55.378	ENSTGUG00000009035	TDP2	96	55.378	Taeniopygia_guttata
ENSDARG00000035954	tdp2b	98	64.550	ENSTRUG00000014347	tdp2b	99	64.550	Takifugu_rubripes
ENSDARG00000035954	tdp2b	70	55.351	ENSTRUG00000012218	-	92	55.351	Takifugu_rubripes
ENSDARG00000035954	tdp2b	98	61.478	ENSTNIG00000017792	tdp2b	99	61.478	Tetraodon_nigroviridis
ENSDARG00000035954	tdp2b	65	58.268	ENSTNIG00000010260	TDP2	96	58.268	Tetraodon_nigroviridis
ENSDARG00000035954	tdp2b	94	52.186	ENSTTRG00000016376	TDP2	93	52.459	Tursiops_truncatus
ENSDARG00000035954	tdp2b	94	49.025	ENSUAMG00000025939	TDP2	93	49.025	Ursus_americanus
ENSDARG00000035954	tdp2b	73	54.093	ENSUMAG00000020111	TDP2	92	54.093	Ursus_maritimus
ENSDARG00000035954	tdp2b	94	52.632	ENSXETG00000014826	tdp2	93	52.632	Xenopus_tropicalis
ENSDARG00000035954	tdp2b	65	55.512	ENSXCOG00000010778	-	70	55.512	Xiphophorus_couchianus
ENSDARG00000035954	tdp2b	67	54.231	ENSXMAG00000022252	-	75	54.231	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000287	magnesium ion binding	-	ISS	Function
GO:0003677	DNA binding	23104058.	IDA	Function
GO:0003697	single-stranded DNA binding	21873635.	IBA	Function
GO:0003697	single-stranded DNA binding	-	ISS	Function
GO:0004518	nuclease activity	-	IEA	Function
GO:0005634	nucleus	-	IEA	Component
GO:0005654	nucleoplasm	21873635.	IBA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0006281	DNA repair	-	IEA	Process
GO:0006302	double-strand break repair	21873635.	IBA	Process
GO:0006302	double-strand break repair	-	ISS	Process
GO:0006974	cellular response to DNA damage stimulus	-	IEA	Process
GO:0007275	multicellular organism development	-	IEA	Process
GO:0007368	determination of left/right symmetry	18039968.	IMP	Process
GO:0007369	gastrulation	18039968.	IMP	Process
GO:0016605	PML body	21873635.	IBA	Component
GO:0016605	PML body	-	ISS	Component
GO:0016787	hydrolase activity	-	IEA	Function
GO:0030145	manganese ion binding	-	ISS	Function
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	18039968.	IMP	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:0060027	convergent extension involved in gastrulation	18039968.	IMP	Process
GO:0070259	tyrosyl-DNA phosphodiesterase activity	29574079.	IDA	Function
GO:0070260	5'-tyrosyl-DNA phosphodiesterase activity	21873635.	IBA	Function
GO:0070260	5'-tyrosyl-DNA phosphodiesterase activity	-	ISS	Function