EuRBPDB

Description

RBDs

Transcripts

Gene Model

Pathways

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSDARG00000040523 (Gene tree)
Gene ID: 567548
Gene Symbol: smpd2a
Alias: nSMase1|neutral SMase I|neutral sphingomyelinase|smpd2
Full Name: sphingomyelin phosphodiesterase 2a%2C neutral membrane (neutral sphingomyelinase)
Gene Type: protein_coding
Species: Danio_rerio
Status: putative
Strand: Plus strand
Length: 22674 bases
Position: chr23:5565261-5587934
Accession: ZDB-GENE-051014-1
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSDARP00000059306	Exo_endo_phos	PF03372.23	3.9e-13	1	1
ENSDARP00000134756	Exo_endo_phos	PF03372.23	3.9e-13	1	1

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSDART00000059307	-	2263	-	ENSDARP00000059306	421 (aa)	-	F1QUD7
ENSDART00000169904	-	2017	XM_005170835	ENSDARP00000134756	421 (aa)	XP_005170892	F1QUD7

Gene Model

Click here to download ENSDARG00000040523's gene model file

Pathways

Pathway ID	Pathway Name	Source
dre00600	Sphingolipid metabolism	KEGG
dre01100	Metabolic pathways	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSDARG00000040523's network

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSDARG00000040523	smpd2a	93	54.839	ENSDARG00000052701	smpd2b	94	55.335

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSDARG00000040523	smpd2a	75	49.533	ENSG00000135587	SMPD2	76	50.000	Homo_sapiens
ENSDARG00000040523	smpd2a	66	54.480	ENSAMEG00000016431	SMPD2	66	54.480	Ailuropoda_melanoleuca
ENSDARG00000040523	smpd2a	98	58.216	ENSACIG00000010069	smpd2b	99	57.981	Amphilophus_citrinellus
ENSDARG00000040523	smpd2a	98	55.809	ENSAOCG00000014544	smpd2b	98	55.581	Amphiprion_ocellaris
ENSDARG00000040523	smpd2a	98	56.751	ENSAPEG00000023764	smpd2b	98	56.522	Amphiprion_percula
ENSDARG00000040523	smpd2a	100	54.955	ENSATEG00000025113	smpd2b	100	54.730	Anabas_testudineus
ENSDARG00000040523	smpd2a	90	46.547	ENSACAG00000009270	SMPD2	97	47.436	Anolis_carolinensis
ENSDARG00000040523	smpd2a	75	49.688	ENSANAG00000028732	SMPD2	76	49.688	Aotus_nancymaae
ENSDARG00000040523	smpd2a	98	57.110	ENSACLG00000022892	smpd2b	98	56.881	Astatotilapia_calliptera
ENSDARG00000040523	smpd2a	92	56.618	ENSAMXG00000013614	smpd2b	95	57.108	Astyanax_mexicanus
ENSDARG00000040523	smpd2a	75	49.688	ENSBTAG00000008145	SMPD2	52	49.688	Bos_taurus
ENSDARG00000040523	smpd2a	89	36.973	WBGene00012105	T27F6.6	82	36.693	Caenorhabditis_elegans
ENSDARG00000040523	smpd2a	75	49.688	ENSCJAG00000005756	SMPD2	76	49.688	Callithrix_jacchus
ENSDARG00000040523	smpd2a	75	49.375	ENSCAFG00000003816	SMPD2	76	49.375	Canis_familiaris
ENSDARG00000040523	smpd2a	75	50.313	ENSCHIG00000022563	SMPD2	76	50.313	Capra_hircus
ENSDARG00000040523	smpd2a	74	51.258	ENSTSYG00000008525	SMPD2	75	51.258	Carlito_syrichta
ENSDARG00000040523	smpd2a	57	50.622	ENSCAPG00000008057	SMPD2	69	50.622	Cavia_aperea
ENSDARG00000040523	smpd2a	66	54.480	ENSCPOG00000003102	SMPD2	74	49.375	Cavia_porcellus
ENSDARG00000040523	smpd2a	75	50.000	ENSCCAG00000036357	SMPD2	76	50.000	Cebus_capucinus
ENSDARG00000040523	smpd2a	75	50.156	ENSCATG00000015266	SMPD2	76	50.156	Cercocebus_atys
ENSDARG00000040523	smpd2a	66	54.874	ENSCLAG00000009948	SMPD2	60	54.874	Chinchilla_lanigera
ENSDARG00000040523	smpd2a	75	50.156	ENSCSAG00000015322	SMPD2	76	50.156	Chlorocebus_sabaeus
ENSDARG00000040523	smpd2a	92	50.990	ENSCPBG00000017837	SMPD2	99	50.873	Chrysemys_picta_bellii
ENSDARG00000040523	smpd2a	75	50.621	ENSCANG00000029491	SMPD2	76	50.621	Colobus_angolensis_palliatus
ENSDARG00000040523	smpd2a	92	46.599	ENSCGRG00001019999	Smpd2	76	52.188	Cricetulus_griseus_chok1gshd
ENSDARG00000040523	smpd2a	92	46.599	ENSCGRG00000008928	Smpd2	76	52.188	Cricetulus_griseus_crigri
ENSDARG00000040523	smpd2a	97	57.176	ENSCSEG00000016030	smpd2b	94	58.993	Cynoglossus_semilaevis
ENSDARG00000040523	smpd2a	100	57.500	ENSCVAG00000020815	smpd2b	100	57.045	Cyprinodon_variegatus
ENSDARG00000040523	smpd2a	75	50.000	ENSDNOG00000003948	SMPD2	75	50.000	Dasypus_novemcinctus
ENSDARG00000040523	smpd2a	75	50.625	ENSDORG00000006485	Smpd2	76	50.625	Dipodomys_ordii
ENSDARG00000040523	smpd2a	68	36.897	FBgn0035421	CG12034	65	36.824	Drosophila_melanogaster
ENSDARG00000040523	smpd2a	93	47.962	ENSEBUG00000002962	smpd2b	97	48.175	Eptatretus_burgeri
ENSDARG00000040523	smpd2a	75	52.188	ENSEASG00005006484	SMPD2	76	52.188	Equus_asinus_asinus
ENSDARG00000040523	smpd2a	75	52.188	ENSECAG00000016972	SMPD2	76	52.188	Equus_caballus
ENSDARG00000040523	smpd2a	100	57.336	ENSELUG00000021534	smpd2b	94	60.192	Esox_lucius
ENSDARG00000040523	smpd2a	75	50.313	ENSFCAG00000006358	SMPD2	76	50.313	Felis_catus
ENSDARG00000040523	smpd2a	91	49.246	ENSFALG00000003639	SMPD2	97	49.246	Ficedula_albicollis
ENSDARG00000040523	smpd2a	100	57.045	ENSFHEG00000017395	smpd2b	100	56.591	Fundulus_heteroclitus
ENSDARG00000040523	smpd2a	95	52.184	ENSGMOG00000015239	smpd2b	94	53.652	Gadus_morhua
ENSDARG00000040523	smpd2a	72	58.306	ENSGALG00000033245	SMPD2	97	50.503	Gallus_gallus
ENSDARG00000040523	smpd2a	100	56.591	ENSGAFG00000016345	smpd2b	100	56.591	Gambusia_affinis
ENSDARG00000040523	smpd2a	95	56.835	ENSGACG00000005132	smpd2b	97	56.731	Gasterosteus_aculeatus
ENSDARG00000040523	smpd2a	94	51.843	ENSGAGG00000023942	SMPD2	99	52.217	Gopherus_agassizii
ENSDARG00000040523	smpd2a	75	50.311	ENSGGOG00000003394	SMPD2	76	50.311	Gorilla_gorilla
ENSDARG00000040523	smpd2a	70	51.689	ENSHGLG00000000226	SMPD2	73	50.327	Heterocephalus_glaber_female
ENSDARG00000040523	smpd2a	70	51.689	ENSHGLG00100016698	SMPD2	73	50.327	Heterocephalus_glaber_male
ENSDARG00000040523	smpd2a	98	53.917	ENSHCOG00000001358	smpd2b	93	56.897	Hippocampus_comes
ENSDARG00000040523	smpd2a	100	60.329	ENSIPUG00000017284	smpd2a	93	63.590	Ictalurus_punctatus
ENSDARG00000040523	smpd2a	93	56.049	ENSIPUG00000024794	smpd2b	95	57.778	Ictalurus_punctatus
ENSDARG00000040523	smpd2a	75	50.938	ENSSTOG00000028661	SMPD2	76	50.938	Ictidomys_tridecemlineatus
ENSDARG00000040523	smpd2a	91	44.987	ENSJJAG00000019368	Smpd2	76	51.553	Jaculus_jaculus
ENSDARG00000040523	smpd2a	100	56.818	ENSKMAG00000015753	smpd2b	100	56.364	Kryptolebias_marmoratus
ENSDARG00000040523	smpd2a	99	54.333	ENSLBEG00000024878	smpd2b	99	54.567	Labrus_bergylta
ENSDARG00000040523	smpd2a	92	52.369	ENSLACG00000016351	smpd2b	97	52.120	Latimeria_chalumnae
ENSDARG00000040523	smpd2a	92	59.113	ENSLOCG00000009741	smpd2b	94	59.360	Lepisosteus_oculatus
ENSDARG00000040523	smpd2a	75	47.516	ENSLAFG00000003298	SMPD2	77	47.516	Loxodonta_africana
ENSDARG00000040523	smpd2a	75	50.156	ENSMFAG00000033236	SMPD2	76	50.156	Macaca_fascicularis
ENSDARG00000040523	smpd2a	75	50.156	ENSMNEG00000042401	SMPD2	76	50.156	Macaca_nemestrina
ENSDARG00000040523	smpd2a	63	50.368	ENSMLEG00000039457	SMPD2	72	50.368	Mandrillus_leucophaeus
ENSDARG00000040523	smpd2a	100	55.856	ENSMAMG00000004710	smpd2b	100	55.631	Mastacembelus_armatus
ENSDARG00000040523	smpd2a	98	56.881	ENSMZEG00005002958	smpd2b	98	56.651	Maylandia_zebra
ENSDARG00000040523	smpd2a	72	57.097	ENSMGAG00000006821	SMPD2	97	49.624	Meleagris_gallopavo
ENSDARG00000040523	smpd2a	70	54.266	ENSMAUG00000008721	Smpd2	70	54.266	Mesocricetus_auratus
ENSDARG00000040523	smpd2a	75	50.938	ENSMICG00000014442	SMPD2	76	50.938	Microcebus_murinus
ENSDARG00000040523	smpd2a	74	51.250	ENSMOCG00000019666	Smpd2	77	51.250	Microtus_ochrogaster
ENSDARG00000040523	smpd2a	98	57.210	ENSMMOG00000012679	smpd2b	99	56.974	Mola_mola
ENSDARG00000040523	smpd2a	72	48.607	ENSMODG00000017971	SMPD2	91	43.035	Monodelphis_domestica
ENSDARG00000040523	smpd2a	97	56.381	ENSMALG00000000267	smpd2b	98	58.151	Monopterus_albus
ENSDARG00000040523	smpd2a	73	51.603	MGP_CAROLIEiJ_G0015268	Smpd2	74	51.603	Mus_caroli
ENSDARG00000040523	smpd2a	73	52.244	ENSMUSG00000019822	Smpd2	74	52.244	Mus_musculus
ENSDARG00000040523	smpd2a	73	52.244	MGP_PahariEiJ_G0030686	Smpd2	74	52.244	Mus_pahari
ENSDARG00000040523	smpd2a	73	52.244	MGP_SPRETEiJ_G0016077	Smpd2	74	52.244	Mus_spretus
ENSDARG00000040523	smpd2a	72	50.974	ENSMPUG00000010005	SMPD2	73	51.299	Mustela_putorius_furo
ENSDARG00000040523	smpd2a	73	50.321	ENSMLUG00000003793	SMPD2	74	50.321	Myotis_lucifugus
ENSDARG00000040523	smpd2a	58	58.436	ENSNGAG00000013670	Smpd2	92	58.436	Nannospalax_galili
ENSDARG00000040523	smpd2a	96	55.711	ENSNBRG00000008403	smpd2b	98	55.478	Neolamprologus_brichardi
ENSDARG00000040523	smpd2a	75	50.000	ENSNLEG00000012570	SMPD2	76	50.000	Nomascus_leucogenys
ENSDARG00000040523	smpd2a	72	46.452	ENSMEUG00000004602	SMPD2	77	45.092	Notamacropus_eugenii
ENSDARG00000040523	smpd2a	75	48.438	ENSOPRG00000012612	SMPD2	75	48.438	Ochotona_princeps
ENSDARG00000040523	smpd2a	98	56.948	ENSONIG00000014702	smpd2b	98	56.720	Oreochromis_niloticus
ENSDARG00000040523	smpd2a	75	51.250	ENSOCUG00000008607	SMPD2	76	51.250	Oryctolagus_cuniculus
ENSDARG00000040523	smpd2a	100	57.466	ENSORLG00000006334	smpd2b	94	59.375	Oryzias_latipes
ENSDARG00000040523	smpd2a	100	57.692	ENSORLG00020015231	smpd2b	94	59.615	Oryzias_latipes_hni
ENSDARG00000040523	smpd2a	100	57.692	ENSORLG00015010424	smpd2b	94	59.615	Oryzias_latipes_hsok
ENSDARG00000040523	smpd2a	98	59.039	ENSOMEG00000016121	smpd2b	98	58.810	Oryzias_melastigma
ENSDARG00000040523	smpd2a	91	45.361	ENSOGAG00000015505	SMPD2	92	45.361	Otolemur_garnettii
ENSDARG00000040523	smpd2a	75	46.319	ENSOARG00000010409	SMPD2	76	46.319	Ovis_aries
ENSDARG00000040523	smpd2a	75	49.844	ENSPPAG00000031363	SMPD2	76	50.311	Pan_paniscus
ENSDARG00000040523	smpd2a	75	49.062	ENSPPRG00000000099	SMPD2	76	49.062	Panthera_pardus
ENSDARG00000040523	smpd2a	75	49.062	ENSPTIG00000008954	SMPD2	76	49.062	Panthera_tigris_altaica
ENSDARG00000040523	smpd2a	75	49.844	ENSPTRG00000018484	SMPD2	76	50.311	Pan_troglodytes
ENSDARG00000040523	smpd2a	75	50.156	ENSPANG00000024480	SMPD2	76	50.156	Papio_anubis
ENSDARG00000040523	smpd2a	94	58.432	ENSPKIG00000011322	smpd2a	92	59.233	Paramormyrops_kingsleyae
ENSDARG00000040523	smpd2a	95	56.145	ENSPMGG00000000230	smpd2b	100	56.386	Periophthalmus_magnuspinnatus
ENSDARG00000040523	smpd2a	75	53.125	ENSPEMG00000018109	Smpd2	78	53.125	Peromyscus_maniculatus_bairdii
ENSDARG00000040523	smpd2a	74	52.201	ENSPMAG00000002460	smpd2b	92	52.025	Petromyzon_marinus
ENSDARG00000040523	smpd2a	72	50.318	ENSPCIG00000005984	SMPD2	77	48.788	Phascolarctos_cinereus
ENSDARG00000040523	smpd2a	100	56.591	ENSPFOG00000014164	smpd2b	100	56.591	Poecilia_formosa
ENSDARG00000040523	smpd2a	100	56.591	ENSPLAG00000014950	smpd2b	100	56.591	Poecilia_latipinna
ENSDARG00000040523	smpd2a	100	56.591	ENSPMEG00000002286	smpd2b	100	56.591	Poecilia_mexicana
ENSDARG00000040523	smpd2a	100	56.818	ENSPREG00000012181	smpd2b	100	56.818	Poecilia_reticulata
ENSDARG00000040523	smpd2a	73	50.955	ENSPPYG00000016908	-	55	50.311	Pongo_abelii
ENSDARG00000040523	smpd2a	91	43.939	ENSPCAG00000011808	SMPD2	77	49.221	Procavia_capensis
ENSDARG00000040523	smpd2a	75	51.250	ENSPCOG00000001714	SMPD2	76	51.250	Propithecus_coquereli
ENSDARG00000040523	smpd2a	81	48.105	ENSPVAG00000006556	SMPD2	70	51.342	Pteropus_vampyrus
ENSDARG00000040523	smpd2a	98	58.080	ENSPNYG00000005567	smpd2b	98	57.845	Pundamilia_nyererei
ENSDARG00000040523	smpd2a	93	56.659	ENSPNAG00000007986	smpd2b	94	57.143	Pygocentrus_nattereri
ENSDARG00000040523	smpd2a	73	50.321	ENSRNOG00000000306	Smpd2	74	50.321	Rattus_norvegicus
ENSDARG00000040523	smpd2a	75	50.467	ENSRBIG00000033388	SMPD2	76	50.932	Rhinopithecus_bieti
ENSDARG00000040523	smpd2a	75	50.156	ENSRROG00000037705	SMPD2	76	50.621	Rhinopithecus_roxellana
ENSDARG00000040523	smpd2a	75	50.313	ENSSBOG00000033929	SMPD2	76	50.313	Saimiri_boliviensis_boliviensis
ENSDARG00000040523	smpd2a	94	62.077	ENSSFOG00015022890	smpd2	94	61.111	Scleropages_formosus
ENSDARG00000040523	smpd2a	97	57.176	ENSSMAG00000008963	smpd2b	95	58.612	Scophthalmus_maximus
ENSDARG00000040523	smpd2a	98	58.352	ENSSDUG00000000098	smpd2b	99	58.124	Seriola_dumerili
ENSDARG00000040523	smpd2a	98	58.962	ENSSLDG00000009497	smpd2b	99	58.726	Seriola_lalandi_dorsalis
ENSDARG00000040523	smpd2a	74	50.158	ENSSARG00000006192	SMPD2	75	50.158	Sorex_araneus
ENSDARG00000040523	smpd2a	92	49.505	ENSSPUG00000013852	SMPD2	98	50.124	Sphenodon_punctatus
ENSDARG00000040523	smpd2a	100	56.054	ENSSPAG00000001844	smpd2b	100	55.830	Stegastes_partitus
ENSDARG00000040523	smpd2a	75	49.062	ENSSSCG00000004408	SMPD2	76	49.062	Sus_scrofa
ENSDARG00000040523	smpd2a	91	48.628	ENSTGUG00000001713	SMPD2	98	47.188	Taeniopygia_guttata
ENSDARG00000040523	smpd2a	97	57.809	ENSTRUG00000025701	smpd2b	99	57.243	Takifugu_rubripes
ENSDARG00000040523	smpd2a	93	60.250	ENSTNIG00000018297	smpd2b	100	59.500	Tetraodon_nigroviridis
ENSDARG00000040523	smpd2a	66	55.914	ENSTBEG00000009336	SMPD2	66	55.914	Tupaia_belangeri
ENSDARG00000040523	smpd2a	74	46.082	ENSTTRG00000004183	SMPD2	75	46.082	Tursiops_truncatus
ENSDARG00000040523	smpd2a	66	54.839	ENSUAMG00000018011	SMPD2	66	54.839	Ursus_americanus
ENSDARG00000040523	smpd2a	56	55.556	ENSUMAG00000025505	SMPD2	57	55.844	Ursus_maritimus
ENSDARG00000040523	smpd2a	81	49.003	ENSXETG00000000421	smpd2	71	55.319	Xenopus_tropicalis
ENSDARG00000040523	smpd2a	96	57.488	ENSXCOG00000015987	smpd2b	99	57.971	Xiphophorus_couchianus
ENSDARG00000040523	smpd2a	100	56.818	ENSXMAG00000018088	smpd2b	100	57.273	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000165	MAPK cascade	25168245.	IDA	Process
GO:0004767	sphingomyelin phosphodiesterase activity	21873635.	IBA	Function
GO:0004767	sphingomyelin phosphodiesterase activity	18678863.	IDA	Function
GO:0004767	sphingomyelin phosphodiesterase activity	15741222.18678863.	IMP	Function
GO:0005794	Golgi apparatus	18678863.	IDA	Component
GO:0005901	caveola	21873635.	IBA	Component
GO:0006684	sphingomyelin metabolic process	21873635.	IBA	Process
GO:0006684	sphingomyelin metabolic process	18678863.	IMP	Process
GO:0016020	membrane	-	IEA	Component
GO:0016021	integral component of membrane	-	IEA	Component
GO:0046513	ceramide biosynthetic process	18678863.	IMP	Process
GO:0071466	cellular response to xenobiotic stimulus	15741222.	IMP	Process
GO:0071502	cellular response to temperature stimulus	25168245.	IDA	Process
GO:0090520	sphingolipid mediated signaling pathway	25168245.	IDA	Process