EuRBPDB

Description

RBDs

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSDARG00000045843 (Gene tree)
Gene ID: 406730
Gene Symbol: apex1
Alias: hm:zehn1532|wu:fc13d11|zap1|zgc:66204
Full Name: APEX nuclease (multifunctional DNA repair enzyme) 1
Gene Type: protein_coding
Species: Danio_rerio
Status: putative
Strand: Plus strand
Length: 6543 bases
Position: chr4:5333988-5340530
Accession: ZDB-GENE-040426-2761
RBP type: canonical RBP
Summary: -

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSDARP00000067373	Exo_endo_phos	PF03372.23	1.1e-19	1	1
ENSDARP00000156404	Exo_endo_phos	PF03372.23	1.1e-19	1	1
ENSDARP00000138791	Exo_endo_phos	PF03372.23	1.4e-19	1	1
ENSDARP00000110718	Exo_endo_phos	PF03372.23	1.5e-19	1	1
ENSDARP00000125208	Exo_endo_phos	PF03372.23	1.6e-06	1	1
ENSDARP00000125428	Exo_endo_phos	PF03372.23	2.4e-06	1	1
ENSDARP00000125593	Exo_endo_phos	PF03372.23	4.3e-06	1	1
ENSDARP00000125549	Exo_endo_phos	PF03372.23	1.5e-05	1	1

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENSDART00000180644	-	2690	-	ENSDARP00000156404	310 (aa)	-	A0A2R9YJQ0
ENSDART00000067374	-	2119	-	ENSDARP00000067373	310 (aa)	-	A0A2R9YJQ0
ENSDART00000150409	-	754	-	ENSDARP00000125428	220 (aa)	-	H0WEZ7
ENSDART00000129398	-	2139	XM_021474983	ENSDARP00000110718	341 (aa)	XP_021330658	F1QTR9
ENSDART00000150620	-	682	-	ENSDARP00000125593	116 (aa)	-	H0WFG1
ENSDART00000163850	-	2136	-	ENSDARP00000138791	340 (aa)	-	A0A0R4IWF9
ENSDART00000150780	-	709	-	ENSDARP00000125208	189 (aa)	-	H0WED1
ENSDART00000150306	-	579	-	ENSDARP00000125549	170 (aa)	-	H0WFB7
ENSDART00000150493	-	388	-	ENSDARP00000125398	105 (aa)	-	H0WEW8

Gene Model

Click here to download ENSDARG00000045843's gene model file

Pathways

Pathway ID	Pathway Name	Source
dre03410	Base excision repair	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSDARG00000045843's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSDARG00000045843	apex1	100	66.038	ENSG00000100823	APEX1	100	66.038	Homo_sapiens
ENSDARG00000045843	apex1	98	82.566	ENSAPOG00000017002	apex1	99	82.566	Acanthochromis_polyacanthus
ENSDARG00000045843	apex1	100	65.723	ENSAMEG00000005418	APEX1	100	65.723	Ailuropoda_melanoleuca
ENSDARG00000045843	apex1	89	87.365	ENSACIG00000010653	apex1	93	87.319	Amphilophus_citrinellus
ENSDARG00000045843	apex1	99	82.143	ENSAOCG00000009649	apex1	99	82.143	Amphiprion_ocellaris
ENSDARG00000045843	apex1	99	82.468	ENSAPEG00000021453	apex1	99	82.468	Amphiprion_percula
ENSDARG00000045843	apex1	99	83.766	ENSATEG00000002883	apex1	97	83.766	Anabas_testudineus
ENSDARG00000045843	apex1	100	72.414	ENSACAG00000008099	APEX1	100	71.924	Anolis_carolinensis
ENSDARG00000045843	apex1	82	30.844	ENSACAG00000011201	APEX2	59	30.820	Anolis_carolinensis
ENSDARG00000045843	apex1	100	66.667	ENSANAG00000030117	APEX1	100	66.981	Aotus_nancymaae
ENSDARG00000045843	apex1	91	87.619	ENSACLG00000018441	apex1	99	85.761	Astatotilapia_calliptera
ENSDARG00000045843	apex1	100	88.782	ENSAMXG00000034699	apex1	100	87.179	Astyanax_mexicanus
ENSDARG00000045843	apex1	100	65.094	ENSBTAG00000002745	APEX1	100	65.094	Bos_taurus
ENSDARG00000045843	apex1	91	42.958	WBGene00001372	exo-3	91	44.318	Caenorhabditis_elegans
ENSDARG00000045843	apex1	100	66.667	ENSCJAG00000009726	APEX1	100	66.981	Callithrix_jacchus
ENSDARG00000045843	apex1	100	65.109	ENSCAFG00000032033	APEX1	100	66.667	Canis_familiaris
ENSDARG00000045843	apex1	100	65.109	ENSCAFG00020014377	-	100	66.667	Canis_lupus_dingo
ENSDARG00000045843	apex1	91	60.000	ENSCAFG00020023002	-	96	58.721	Canis_lupus_dingo
ENSDARG00000045843	apex1	100	65.094	ENSCHIG00000007298	-	100	65.094	Capra_hircus
ENSDARG00000045843	apex1	89	55.036	ENSCHIG00000014537	-	86	56.089	Capra_hircus
ENSDARG00000045843	apex1	100	65.094	ENSTSYG00000034813	APEX1	100	64.780	Carlito_syrichta
ENSDARG00000045843	apex1	87	64.000	ENSCAPG00000016235	APEX1	91	70.763	Cavia_aperea
ENSDARG00000045843	apex1	100	66.352	ENSCPOG00000030909	APEX1	100	66.038	Cavia_porcellus
ENSDARG00000045843	apex1	100	66.667	ENSCCAG00000033056	-	100	66.981	Cebus_capucinus
ENSDARG00000045843	apex1	100	58.491	ENSCCAG00000031931	-	100	58.491	Cebus_capucinus
ENSDARG00000045843	apex1	100	65.723	ENSCATG00000015580	APEX1	100	65.723	Cercocebus_atys
ENSDARG00000045843	apex1	100	65.723	ENSCLAG00000001002	APEX1	100	65.409	Chinchilla_lanigera
ENSDARG00000045843	apex1	100	66.038	ENSCSAG00000016670	-	100	66.038	Chlorocebus_sabaeus
ENSDARG00000045843	apex1	100	66.038	ENSCSAG00000016685	-	100	66.038	Chlorocebus_sabaeus
ENSDARG00000045843	apex1	100	71.698	ENSCPBG00000009567	APEX1	100	71.698	Chrysemys_picta_bellii
ENSDARG00000045843	apex1	95	57.095	ENSCING00000008137	-	85	60.448	Ciona_intestinalis
ENSDARG00000045843	apex1	86	52.985	ENSCSAVG00000007144	-	100	54.651	Ciona_savignyi
ENSDARG00000045843	apex1	100	66.038	ENSCANG00000030726	APEX1	100	66.038	Colobus_angolensis_palliatus
ENSDARG00000045843	apex1	100	64.353	ENSCGRG00001017046	Apex1	100	64.669	Cricetulus_griseus_chok1gshd
ENSDARG00000045843	apex1	100	64.353	ENSCGRG00000008984	Apex1	100	64.669	Cricetulus_griseus_crigri
ENSDARG00000045843	apex1	99	81.230	ENSCSEG00000017499	apex1	99	81.230	Cynoglossus_semilaevis
ENSDARG00000045843	apex1	99	85.761	ENSCVAG00000022075	apex1	99	85.761	Cyprinodon_variegatus
ENSDARG00000045843	apex1	100	62.264	ENSDNOG00000042234	APEX1	95	62.264	Dasypus_novemcinctus
ENSDARG00000045843	apex1	100	65.723	ENSDORG00000001616	Apex1	100	65.094	Dipodomys_ordii
ENSDARG00000045843	apex1	100	66.667	ENSETEG00000004855	-	100	66.667	Echinops_telfairi
ENSDARG00000045843	apex1	76	60.924	ENSEBUG00000000622	-	92	60.924	Eptatretus_burgeri
ENSDARG00000045843	apex1	100	66.352	ENSEASG00005017489	APEX1	74	66.038	Equus_asinus_asinus
ENSDARG00000045843	apex1	100	66.352	ENSECAG00000022325	APEX1	82	66.038	Equus_caballus
ENSDARG00000045843	apex1	86	69.517	ENSEEUG00000012569	APEX1	97	65.203	Erinaceus_europaeus
ENSDARG00000045843	apex1	100	83.013	ENSELUG00000021706	apex1	100	83.333	Esox_lucius
ENSDARG00000045843	apex1	100	66.667	ENSFCAG00000030869	APEX1	100	66.352	Felis_catus
ENSDARG00000045843	apex1	100	66.667	ENSFDAG00000006120	APEX1	100	66.352	Fukomys_damarensis
ENSDARG00000045843	apex1	99	85.437	ENSFHEG00000009031	apex1	91	79.240	Fundulus_heteroclitus
ENSDARG00000045843	apex1	99	77.097	ENSGMOG00000007943	apex1	99	77.346	Gadus_morhua
ENSDARG00000045843	apex1	99	85.437	ENSGAFG00000005311	apex1	99	85.437	Gambusia_affinis
ENSDARG00000045843	apex1	99	84.142	ENSGACG00000019497	apex1	99	86.466	Gasterosteus_aculeatus
ENSDARG00000045843	apex1	100	71.384	ENSGAGG00000014999	APEX1	100	71.384	Gopherus_agassizii
ENSDARG00000045843	apex1	100	65.723	ENSGGOG00000002128	APEX1	100	65.723	Gorilla_gorilla
ENSDARG00000045843	apex1	99	85.390	ENSHBUG00000005894	apex1	99	85.390	Haplochromis_burtoni
ENSDARG00000045843	apex1	100	67.610	ENSHGLG00000002848	APEX1	100	66.352	Heterocephalus_glaber_female
ENSDARG00000045843	apex1	100	67.610	ENSHGLG00100017878	APEX1	100	66.352	Heterocephalus_glaber_male
ENSDARG00000045843	apex1	99	83.226	ENSHCOG00000009961	apex1	99	83.226	Hippocampus_comes
ENSDARG00000045843	apex1	100	86.495	ENSIPUG00000005799	apex1	100	84.887	Ictalurus_punctatus
ENSDARG00000045843	apex1	100	66.038	ENSSTOG00000010096	APEX1	100	66.038	Ictidomys_tridecemlineatus
ENSDARG00000045843	apex1	100	64.780	ENSJJAG00000012067	-	100	64.780	Jaculus_jaculus
ENSDARG00000045843	apex1	100	57.547	ENSJJAG00000003660	-	100	57.547	Jaculus_jaculus
ENSDARG00000045843	apex1	90	62.007	ENSJJAG00000020465	-	93	58.497	Jaculus_jaculus
ENSDARG00000045843	apex1	99	83.172	ENSKMAG00000021171	apex1	99	83.172	Kryptolebias_marmoratus
ENSDARG00000045843	apex1	99	83.172	ENSLBEG00000010248	apex1	99	83.172	Labrus_bergylta
ENSDARG00000045843	apex1	100	76.115	ENSLACG00000008617	APEX1	100	75.159	Latimeria_chalumnae
ENSDARG00000045843	apex1	100	81.587	ENSLOCG00000015516	apex1	100	81.073	Lepisosteus_oculatus
ENSDARG00000045843	apex1	100	66.667	ENSLAFG00000021872	APEX1	100	66.981	Loxodonta_africana
ENSDARG00000045843	apex1	100	65.409	ENSMFAG00000002565	APEX1	100	65.409	Macaca_fascicularis
ENSDARG00000045843	apex1	100	65.409	ENSMMUG00000048039	APEX1	100	65.409	Macaca_mulatta
ENSDARG00000045843	apex1	100	65.409	ENSMNEG00000036944	APEX1	100	65.409	Macaca_nemestrina
ENSDARG00000045843	apex1	100	65.723	ENSMLEG00000042125	APEX1	100	65.723	Mandrillus_leucophaeus
ENSDARG00000045843	apex1	99	84.142	ENSMAMG00000023526	apex1	99	84.142	Mastacembelus_armatus
ENSDARG00000045843	apex1	91	87.619	ENSMZEG00005014187	apex1	99	85.761	Maylandia_zebra
ENSDARG00000045843	apex1	100	64.241	ENSMAUG00000013994	Apex1	100	64.241	Mesocricetus_auratus
ENSDARG00000045843	apex1	100	65.094	ENSMICG00000043554	APEX1	100	65.409	Microcebus_murinus
ENSDARG00000045843	apex1	100	64.669	ENSMOCG00000013721	Apex1	100	64.669	Microtus_ochrogaster
ENSDARG00000045843	apex1	98	84.043	ENSMMOG00000010031	apex1	100	81.562	Mola_mola
ENSDARG00000045843	apex1	100	64.062	ENSMODG00000007125	APEX1	100	64.688	Monodelphis_domestica
ENSDARG00000045843	apex1	91	84.762	ENSMALG00000011699	apex1	79	79.522	Monopterus_albus
ENSDARG00000045843	apex1	99	66.139	MGP_CAROLIEiJ_G0019209	Apex1	99	66.456	Mus_caroli
ENSDARG00000045843	apex1	100	65.931	ENSMUSG00000035960	Apex1	100	65.931	Mus_musculus
ENSDARG00000045843	apex1	100	65.931	MGP_PahariEiJ_G0030232	Apex1	100	65.931	Mus_pahari
ENSDARG00000045843	apex1	100	65.931	MGP_SPRETEiJ_G0020101	Apex1	100	65.931	Mus_spretus
ENSDARG00000045843	apex1	100	64.688	ENSMLUG00000028957	APEX1	100	64.688	Myotis_lucifugus
ENSDARG00000045843	apex1	99	45.408	ENSNGAG00000021748	-	86	53.763	Nannospalax_galili
ENSDARG00000045843	apex1	100	65.409	ENSNGAG00000002725	-	100	65.409	Nannospalax_galili
ENSDARG00000045843	apex1	100	78.886	ENSNBRG00000005334	apex1	97	80.909	Neolamprologus_brichardi
ENSDARG00000045843	apex1	100	66.454	ENSNLEG00000010839	APEX1	100	66.773	Nomascus_leucogenys
ENSDARG00000045843	apex1	100	65.287	ENSMEUG00000014519	APEX1	100	64.650	Notamacropus_eugenii
ENSDARG00000045843	apex1	100	66.246	ENSOPRG00000014029	APEX1	100	65.931	Ochotona_princeps
ENSDARG00000045843	apex1	100	66.038	ENSODEG00000001703	-	100	65.723	Octodon_degus
ENSDARG00000045843	apex1	100	51.543	ENSODEG00000006583	-	100	51.543	Octodon_degus
ENSDARG00000045843	apex1	97	52.318	ENSODEG00000004777	-	83	56.746	Octodon_degus
ENSDARG00000045843	apex1	91	87.619	ENSONIG00000012089	apex1	99	85.437	Oreochromis_niloticus
ENSDARG00000045843	apex1	88	70.909	ENSOANG00000008836	APEX1	82	63.526	Ornithorhynchus_anatinus
ENSDARG00000045843	apex1	100	67.296	ENSOCUG00000005022	APEX1	100	67.610	Oryctolagus_cuniculus
ENSDARG00000045843	apex1	99	85.484	ENSORLG00000012378	apex1	99	85.484	Oryzias_latipes
ENSDARG00000045843	apex1	99	85.484	ENSORLG00020021371	apex1	99	85.484	Oryzias_latipes_hni
ENSDARG00000045843	apex1	99	85.484	ENSORLG00015020089	apex1	99	85.484	Oryzias_latipes_hsok
ENSDARG00000045843	apex1	99	86.452	ENSOMEG00000018876	apex1	99	86.452	Oryzias_melastigma
ENSDARG00000045843	apex1	90	61.649	ENSOGAG00000029355	-	88	61.733	Otolemur_garnettii
ENSDARG00000045843	apex1	100	65.409	ENSOGAG00000013335	-	100	65.723	Otolemur_garnettii
ENSDARG00000045843	apex1	96	56.291	ENSOARG00000014424	-	88	58.333	Ovis_aries
ENSDARG00000045843	apex1	100	65.094	ENSOARG00000019740	-	100	65.094	Ovis_aries
ENSDARG00000045843	apex1	97	62.013	ENSOARG00000001876	-	100	62.013	Ovis_aries
ENSDARG00000045843	apex1	100	66.773	ENSPPAG00000038760	APEX1	100	66.773	Pan_paniscus
ENSDARG00000045843	apex1	100	66.667	ENSPPRG00000011794	APEX1	100	66.667	Panthera_pardus
ENSDARG00000045843	apex1	100	66.667	ENSPTIG00000014829	APEX1	100	66.352	Panthera_tigris_altaica
ENSDARG00000045843	apex1	100	66.773	ENSPTRG00000006093	APEX1	100	66.773	Pan_troglodytes
ENSDARG00000045843	apex1	100	65.723	ENSPANG00000022757	APEX1	100	65.723	Papio_anubis
ENSDARG00000045843	apex1	89	88.406	ENSPKIG00000003504	apex1	100	85.032	Paramormyrops_kingsleyae
ENSDARG00000045843	apex1	86	76.404	ENSPMGG00000016596	apex1	78	76.404	Periophthalmus_magnuspinnatus
ENSDARG00000045843	apex1	100	64.669	ENSPEMG00000019097	Apex1	100	64.984	Peromyscus_maniculatus_bairdii
ENSDARG00000045843	apex1	93	73.196	ENSPMAG00000007275	-	94	74.368	Petromyzon_marinus
ENSDARG00000045843	apex1	100	63.950	ENSPCIG00000023274	APEX1	100	63.636	Phascolarctos_cinereus
ENSDARG00000045843	apex1	99	85.113	ENSPFOG00000004178	apex1	99	85.113	Poecilia_formosa
ENSDARG00000045843	apex1	99	85.761	ENSPLAG00000012779	apex1	99	85.761	Poecilia_latipinna
ENSDARG00000045843	apex1	99	85.113	ENSPMEG00000019623	apex1	99	85.113	Poecilia_mexicana
ENSDARG00000045843	apex1	99	84.466	ENSPREG00000014298	apex1	100	83.601	Poecilia_reticulata
ENSDARG00000045843	apex1	100	65.409	ENSPPYG00000005565	APEX1	100	65.409	Pongo_abelii
ENSDARG00000045843	apex1	100	64.151	ENSPCAG00000010376	APEX1	100	64.465	Procavia_capensis
ENSDARG00000045843	apex1	100	65.409	ENSPCOG00000021564	APEX1	100	65.723	Propithecus_coquereli
ENSDARG00000045843	apex1	100	65.421	ENSPVAG00000010736	APEX1	100	65.625	Pteropus_vampyrus
ENSDARG00000045843	apex1	91	87.619	ENSPNYG00000023940	apex1	99	85.761	Pundamilia_nyererei
ENSDARG00000045843	apex1	100	86.387	ENSPNAG00000020897	apex1	96	85.017	Pygocentrus_nattereri
ENSDARG00000045843	apex1	100	65.300	ENSRNOG00000009663	Apex1	100	65.615	Rattus_norvegicus
ENSDARG00000045843	apex1	100	66.038	ENSRBIG00000038325	APEX1	99	66.038	Rhinopithecus_bieti
ENSDARG00000045843	apex1	100	66.667	ENSSBOG00000018921	-	100	66.981	Saimiri_boliviensis_boliviensis
ENSDARG00000045843	apex1	100	58.842	ENSSBOG00000031372	-	100	59.355	Saimiri_boliviensis_boliviensis
ENSDARG00000045843	apex1	100	63.272	ENSSHAG00000013524	APEX1	100	63.272	Sarcophilus_harrisii
ENSDARG00000045843	apex1	100	80.707	ENSSFOG00015001948	apex1	100	83.280	Scleropages_formosus
ENSDARG00000045843	apex1	96	84.899	ENSSMAG00000013348	apex1	99	82.484	Scophthalmus_maximus
ENSDARG00000045843	apex1	99	85.113	ENSSDUG00000016377	apex1	99	85.113	Seriola_dumerili
ENSDARG00000045843	apex1	99	85.113	ENSSLDG00000023005	apex1	99	85.113	Seriola_lalandi_dorsalis
ENSDARG00000045843	apex1	99	70.874	ENSSPUG00000000531	APEX1	99	70.130	Sphenodon_punctatus
ENSDARG00000045843	apex1	99	82.524	ENSSPAG00000000458	apex1	99	82.524	Stegastes_partitus
ENSDARG00000045843	apex1	94	40.067	ENSSSCG00000039705	-	83	43.426	Sus_scrofa
ENSDARG00000045843	apex1	100	65.409	ENSSSCG00000040060	-	100	65.409	Sus_scrofa
ENSDARG00000045843	apex1	76	59.574	ENSTGUG00000014378	APEX1	100	59.574	Taeniopygia_guttata
ENSDARG00000045843	apex1	89	84.477	ENSTRUG00000004268	apex1	99	76.261	Takifugu_rubripes
ENSDARG00000045843	apex1	99	82.792	ENSTNIG00000005778	apex1	99	82.792	Tetraodon_nigroviridis
ENSDARG00000045843	apex1	100	62.928	ENSTBEG00000006405	APEX1	100	63.522	Tupaia_belangeri
ENSDARG00000045843	apex1	76	69.787	ENSTTRG00000007860	APEX1	100	69.787	Tursiops_truncatus
ENSDARG00000045843	apex1	100	65.723	ENSUAMG00000010457	APEX1	100	65.409	Ursus_americanus
ENSDARG00000045843	apex1	83	30.065	ENSUMAG00000002892	APEX2	59	30.065	Ursus_maritimus
ENSDARG00000045843	apex1	100	65.723	ENSUMAG00000009178	APEX1	100	65.409	Ursus_maritimus
ENSDARG00000045843	apex1	76	65.106	ENSVPAG00000005083	APEX1	100	65.106	Vicugna_pacos
ENSDARG00000045843	apex1	100	64.798	ENSVVUG00000009010	APEX1	100	66.352	Vulpes_vulpes
ENSDARG00000045843	apex1	100	69.620	ENSXETG00000024773	apex1	100	69.937	Xenopus_tropicalis
ENSDARG00000045843	apex1	99	86.084	ENSXCOG00000015233	apex1	99	86.084	Xiphophorus_couchianus
ENSDARG00000045843	apex1	99	86.084	ENSXMAG00000006195	apex1	99	86.084	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001947	heart looping	16966376.	IMP	Process
GO:0003677	DNA binding	-	IEA	Function
GO:0003723	RNA binding	-	IEA	Function
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	21873635.	IBA	Function
GO:0004518	nuclease activity	-	IEA	Function
GO:0004519	endonuclease activity	-	IEA	Function
GO:0004528	phosphodiesterase I activity	21873635.	IBA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	-	IEA	Component
GO:0005730	nucleolus	-	IEA	Component
GO:0005737	cytoplasm	-	IEA	Component
GO:0005739	mitochondrion	-	IEA	Component
GO:0005783	endoplasmic reticulum	-	IEA	Component
GO:0006281	DNA repair	-	IEA	Process
GO:0006284	base-excision repair	21873635.	IBA	Process
GO:0006974	cellular response to DNA damage stimulus	-	IEA	Process
GO:0008311	double-stranded DNA 3'-5' exodeoxyribonuclease activity	21873635.	IBA	Function
GO:0010628	positive regulation of gene expression	21172930.	IMP	Process
GO:0016491	oxidoreductase activity	18579163.	IDA	Function
GO:0016607	nuclear speck	-	IEA	Component
GO:0016787	hydrolase activity	-	IEA	Function
GO:0016829	lyase activity	-	IEA	Function
GO:0043066	negative regulation of apoptotic process	16966376.	IMP	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:0060047	heart contraction	16966376.	IMP	Process
GO:0080111	DNA demethylation	-	ISS	Process
GO:0140078	class I DNA-(apurinic or apyrimidinic site) endonuclease activity	-	IEA	Function