EuRBPDB

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000004059 (Gene tree)
Gene ID: 381
Gene Symbol: ARF5
Alias: -
Full Name: ADP ribosylation factor 5
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 3,361 bases
Position: chr7:127,588,345-127,591,705
Accession: 658
RBP type: canonical RBP
Summary: This gene is a member of the human ADP-ribosylation factor (ARF) gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 6 ARF proteins and 11 ARF-like proteins and constitute 1 family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2,and ARF3), class II (ARF4 and ARF5) and class III (ARF6). The members of each class share a common gene organization. [provided by RefSeq, Dec 2010]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000412701	MMR_HSR1	PF01926.23	0.0001	1	1
ENSP00000000233	MMR_HSR1	PF01926.23	0.00013	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
30655362	Rab1b and ARF5 are novel RNA-binding proteins involved in FMDV IRES-driven RNA localization.	Life Sci Alliance	2019 Jan 17	Fernandez-Chamorro J	doi: 10.26508/lsa.201800131

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000463733	ARF5-204	1509	-	-	- (aa)	-	-
ENST00000459680	ARF5-203	466	-	-	- (aa)	-	-
ENST00000000233	ARF5-201	1103	-	ENSP00000000233	180 (aa)	-	P84085
ENST00000467281	ARF5-205	567	-	-	- (aa)	-	-
ENST00000489673	ARF5-206	566	-	-	- (aa)	-	-
ENST00000415666	ARF5-202	546	-	ENSP00000412701	150 (aa)	-	C9J1Z8

Gene Model

Click here to download ENSG00000004059's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa04144	Endocytosis	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000004059's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000004059	ARF5	100	86.184	ENSAPOG00000000667	-	99	86.034	Acanthochromis_polyacanthus
ENSG00000004059	ARF5	100	100.000	ENSAMEG00000004635	ARF5	100	100.000	Ailuropoda_melanoleuca
ENSG00000004059	ARF5	100	91.111	ENSACIG00000005843	arf5	100	91.111	Amphilophus_citrinellus
ENSG00000004059	ARF5	100	88.158	ENSACIG00000000467	-	99	87.709	Amphilophus_citrinellus
ENSG00000004059	ARF5	96	73.973	ENSACIG00000014610	zgc:110286	100	69.444	Amphilophus_citrinellus
ENSG00000004059	ARF5	100	90.132	ENSAOCG00000023329	arf5	100	90.000	Amphiprion_ocellaris
ENSG00000004059	ARF5	100	86.184	ENSAOCG00000008113	-	99	86.034	Amphiprion_ocellaris
ENSG00000004059	ARF5	100	90.132	ENSAPEG00000024614	arf5	100	90.000	Amphiprion_percula
ENSG00000004059	ARF5	100	86.184	ENSAPEG00000003087	-	99	86.034	Amphiprion_percula
ENSG00000004059	ARF5	100	91.111	ENSATEG00000003053	ARF5	100	91.111	Anabas_testudineus
ENSG00000004059	ARF5	100	87.500	ENSATEG00000001302	-	99	86.592	Anabas_testudineus
ENSG00000004059	ARF5	100	100.000	ENSANAG00000026446	ARF5	100	100.000	Aotus_nancymaae
ENSG00000004059	ARF5	100	91.667	ENSACLG00000005705	arf5	100	91.667	Astatotilapia_calliptera
ENSG00000004059	ARF5	100	87.500	ENSACLG00000025604	-	99	87.151	Astatotilapia_calliptera
ENSG00000004059	ARF5	100	91.667	ENSAMXG00000031467	arf4a	100	91.667	Astyanax_mexicanus
ENSG00000004059	ARF5	100	93.333	ENSAMXG00000038224	-	100	93.333	Astyanax_mexicanus
ENSG00000004059	ARF5	100	93.889	ENSAMXG00000004249	-	100	93.889	Astyanax_mexicanus
ENSG00000004059	ARF5	100	91.667	ENSAMXG00000031774	ARF5	100	91.667	Astyanax_mexicanus
ENSG00000004059	ARF5	100	100.000	ENSBTAG00000009366	ARF5	100	100.000	Bos_taurus
ENSG00000004059	ARF5	99	85.430	WBGene00000183	arf-3	99	84.916	Caenorhabditis_elegans
ENSG00000004059	ARF5	100	100.000	ENSCJAG00000017604	ARF5	100	100.000	Callithrix_jacchus
ENSG00000004059	ARF5	100	98.684	ENSCAFG00020021629	ARF5	100	84.112	Canis_lupus_dingo
ENSG00000004059	ARF5	100	100.000	ENSCHIG00000018906	ARF5	100	100.000	Capra_hircus
ENSG00000004059	ARF5	99	98.675	ENSCPOG00000006239	ARF5	100	97.238	Cavia_porcellus
ENSG00000004059	ARF5	100	100.000	ENSCCAG00000027943	-	100	100.000	Cebus_capucinus
ENSG00000004059	ARF5	100	100.000	ENSCATG00000010217	ARF5	100	100.000	Cercocebus_atys
ENSG00000004059	ARF5	100	100.000	ENSCLAG00000007930	ARF5	100	100.000	Chinchilla_lanigera
ENSG00000004059	ARF5	100	100.000	ENSCSAG00000010208	ARF5	100	100.000	Chlorocebus_sabaeus
ENSG00000004059	ARF5	99	77.095	ENSCING00000004846	-	99	77.095	Ciona_intestinalis
ENSG00000004059	ARF5	99	74.033	ENSCSAVG00000001959	-	99	74.033	Ciona_savignyi
ENSG00000004059	ARF5	89	98.137	ENSCANG00000037234	ARF5	98	98.137	Colobus_angolensis_palliatus
ENSG00000004059	ARF5	100	100.000	ENSCGRG00001024919	Arf5	100	100.000	Cricetulus_griseus_chok1gshd
ENSG00000004059	ARF5	100	86.667	ENSCSEG00000006004	arf5	100	86.667	Cynoglossus_semilaevis
ENSG00000004059	ARF5	100	91.667	ENSCVAG00000007314	-	100	91.667	Cyprinodon_variegatus
ENSG00000004059	ARF5	100	91.667	ENSCVAG00000009124	ARF5	100	91.667	Cyprinodon_variegatus
ENSG00000004059	ARF5	100	88.158	ENSCVAG00000011381	-	99	87.709	Cyprinodon_variegatus
ENSG00000004059	ARF5	100	93.333	ENSDARG00000070472	arf5	100	93.333	Danio_rerio
ENSG00000004059	ARF5	100	93.889	ENSDARG00000113899	zgc:77650	100	93.889	Danio_rerio
ENSG00000004059	ARF5	100	91.667	ENSDARG00000045989	arf4a	100	91.667	Danio_rerio
ENSG00000004059	ARF5	100	71.271	ENSDARG00000074210	ARF5	89	71.271	Danio_rerio
ENSG00000004059	ARF5	100	100.000	ENSDORG00000000325	Arf5	100	100.000	Dipodomys_ordii
ENSG00000004059	ARF5	99	85.430	FBgn0013749	Arf102F	100	83.889	Drosophila_melanogaster
ENSG00000004059	ARF5	97	96.571	ENSETEG00000009275	ARF5	100	96.571	Echinops_telfairi
ENSG00000004059	ARF5	100	84.211	ENSEBUG00000014420	-	100	83.889	Eptatretus_burgeri
ENSG00000004059	ARF5	100	69.737	ENSEBUG00000004484	-	99	69.274	Eptatretus_burgeri
ENSG00000004059	ARF5	97	77.703	ENSELUG00000014428	arf4	99	74.860	Esox_lucius
ENSG00000004059	ARF5	100	100.000	ENSFCAG00000005482	ARF5	100	100.000	Felis_catus
ENSG00000004059	ARF5	100	91.111	ENSFHEG00000023119	arf5	100	91.111	Fundulus_heteroclitus
ENSG00000004059	ARF5	100	88.889	ENSGMOG00000008747	arf5	100	88.889	Gadus_morhua
ENSG00000004059	ARF5	100	88.889	ENSGMOG00000019109	-	99	88.889	Gadus_morhua
ENSG00000004059	ARF5	100	91.667	ENSGAFG00000018703	arf5	100	91.667	Gambusia_affinis
ENSG00000004059	ARF5	99	86.755	ENSGAFG00000005163	-	99	86.034	Gambusia_affinis
ENSG00000004059	ARF5	99	87.417	ENSGACG00000012500	-	99	84.916	Gasterosteus_aculeatus
ENSG00000004059	ARF5	100	89.474	ENSGACG00000000686	arf5	100	89.444	Gasterosteus_aculeatus
ENSG00000004059	ARF5	100	98.333	ENSGAGG00000000231	ARF5	100	98.333	Gopherus_agassizii
ENSG00000004059	ARF5	100	100.000	ENSGGOG00000016749	ARF5	100	100.000	Gorilla_gorilla
ENSG00000004059	ARF5	100	87.500	ENSHBUG00000011041	-	99	87.151	Haplochromis_burtoni
ENSG00000004059	ARF5	100	91.667	ENSHBUG00000008546	arf5	100	91.667	Haplochromis_burtoni
ENSG00000004059	ARF5	100	100.000	ENSHGLG00000007494	ARF5	100	100.000	Heterocephalus_glaber_female
ENSG00000004059	ARF5	100	98.684	ENSHGLG00100006040	ARF5	60	98.333	Heterocephalus_glaber_male
ENSG00000004059	ARF5	99	84.106	ENSHCOG00000015577	-	100	83.799	Hippocampus_comes
ENSG00000004059	ARF5	100	93.889	ENSIPUG00000004159	Arf5	100	93.889	Ictalurus_punctatus
ENSG00000004059	ARF5	100	92.778	ENSIPUG00000004215	arf5	100	92.778	Ictalurus_punctatus
ENSG00000004059	ARF5	100	92.222	ENSIPUG00000007016	arf4	100	92.222	Ictalurus_punctatus
ENSG00000004059	ARF5	100	71.111	ENSIPUG00000006913	-	70	71.111	Ictalurus_punctatus
ENSG00000004059	ARF5	100	100.000	ENSSTOG00000002104	ARF5	100	100.000	Ictidomys_tridecemlineatus
ENSG00000004059	ARF5	100	100.000	ENSJJAG00000005105	Arf5	100	100.000	Jaculus_jaculus
ENSG00000004059	ARF5	100	88.816	ENSKMAG00000012816	-	99	87.709	Kryptolebias_marmoratus
ENSG00000004059	ARF5	100	85.000	ENSLBEG00000012002	-	99	85.000	Labrus_bergylta
ENSG00000004059	ARF5	100	90.000	ENSLBEG00000026532	arf5	100	90.000	Labrus_bergylta
ENSG00000004059	ARF5	100	100.000	ENSLAFG00000011469	ARF5	100	100.000	Loxodonta_africana
ENSG00000004059	ARF5	100	100.000	ENSMFAG00000019772	ARF5	100	100.000	Macaca_fascicularis
ENSG00000004059	ARF5	100	100.000	ENSMMUG00000046381	ARF5	100	100.000	Macaca_mulatta
ENSG00000004059	ARF5	100	100.000	ENSMNEG00000040893	ARF5	100	100.000	Macaca_nemestrina
ENSG00000004059	ARF5	100	90.556	ENSMAMG00000021160	arf5	100	90.556	Mastacembelus_armatus
ENSG00000004059	ARF5	100	88.158	ENSMAMG00000008223	-	99	87.151	Mastacembelus_armatus
ENSG00000004059	ARF5	87	88.535	ENSMZEG00005019741	-	93	88.535	Maylandia_zebra
ENSG00000004059	ARF5	100	91.667	ENSMZEG00005015033	arf5	67	91.667	Maylandia_zebra
ENSG00000004059	ARF5	100	100.000	ENSMAUG00000014825	Arf5	100	100.000	Mesocricetus_auratus
ENSG00000004059	ARF5	100	100.000	ENSMICG00000000091	ARF5	100	100.000	Microcebus_murinus
ENSG00000004059	ARF5	100	100.000	ENSMOCG00000022861	Arf5	100	100.000	Microtus_ochrogaster
ENSG00000004059	ARF5	100	98.889	ENSMODG00000015229	ARF5	100	98.889	Monodelphis_domestica
ENSG00000004059	ARF5	97	70.946	ENSMALG00000022638	zgc:110286	100	68.715	Monopterus_albus
ENSG00000004059	ARF5	100	91.111	ENSMALG00000010117	-	100	91.111	Monopterus_albus
ENSG00000004059	ARF5	100	88.816	ENSMALG00000006020	-	99	87.709	Monopterus_albus
ENSG00000004059	ARF5	100	100.000	MGP_CAROLIEiJ_G0028156	Arf5	100	100.000	Mus_caroli
ENSG00000004059	ARF5	100	100.000	ENSMUSG00000020440	Arf5	100	100.000	Mus_musculus
ENSG00000004059	ARF5	100	100.000	MGP_PahariEiJ_G0021914	Arf5	100	100.000	Mus_pahari
ENSG00000004059	ARF5	100	100.000	MGP_SPRETEiJ_G0029156	Arf5	100	100.000	Mus_spretus
ENSG00000004059	ARF5	100	100.000	ENSMPUG00000006675	ARF5	100	100.000	Mustela_putorius_furo
ENSG00000004059	ARF5	100	100.000	ENSMLUG00000017122	ARF5	100	100.000	Myotis_lucifugus
ENSG00000004059	ARF5	100	100.000	ENSNGAG00000011743	Arf5	100	100.000	Nannospalax_galili
ENSG00000004059	ARF5	100	91.667	ENSNBRG00000018854	arf5	100	91.667	Neolamprologus_brichardi
ENSG00000004059	ARF5	100	100.000	ENSODEG00000011800	ARF5	100	100.000	Octodon_degus
ENSG00000004059	ARF5	100	91.667	ENSONIG00000007594	arf5	100	91.667	Oreochromis_niloticus
ENSG00000004059	ARF5	100	87.500	ENSONIG00000014890	-	99	87.151	Oreochromis_niloticus
ENSG00000004059	ARF5	100	100.000	ENSOCUG00000024365	ARF5	100	100.000	Oryctolagus_cuniculus
ENSG00000004059	ARF5	100	87.500	ENSORLG00020001755	-	99	87.151	Oryzias_latipes_hni
ENSG00000004059	ARF5	100	87.500	ENSOMEG00000000211	-	64	87.151	Oryzias_melastigma
ENSG00000004059	ARF5	100	91.111	ENSOMEG00000020821	ARF5	100	91.111	Oryzias_melastigma
ENSG00000004059	ARF5	100	100.000	ENSOGAG00000013336	ARF5	100	100.000	Otolemur_garnettii
ENSG00000004059	ARF5	100	100.000	ENSPPAG00000037755	ARF5	100	100.000	Pan_paniscus
ENSG00000004059	ARF5	100	100.000	ENSPPRG00000004674	ARF5	100	100.000	Panthera_pardus
ENSG00000004059	ARF5	100	100.000	ENSPTRG00000019651	ARF5	100	100.000	Pan_troglodytes
ENSG00000004059	ARF5	100	100.000	ENSPANG00000032970	ARF5	100	100.000	Papio_anubis
ENSG00000004059	ARF5	100	91.111	ENSPKIG00000025381	-	100	91.111	Paramormyrops_kingsleyae
ENSG00000004059	ARF5	100	90.556	ENSPKIG00000013814	-	100	90.556	Paramormyrops_kingsleyae
ENSG00000004059	ARF5	100	91.667	ENSPKIG00000025349	arf4a	100	91.667	Paramormyrops_kingsleyae
ENSG00000004059	ARF5	100	85.526	ENSPMGG00000009985	-	100	85.000	Periophthalmus_magnuspinnatus
ENSG00000004059	ARF5	100	100.000	ENSPEMG00000021476	Arf5	100	100.000	Peromyscus_maniculatus_bairdii
ENSG00000004059	ARF5	100	78.947	ENSPMAG00000009600	arf4a	100	78.771	Petromyzon_marinus
ENSG00000004059	ARF5	100	91.667	ENSPFOG00000015817	arf5	100	91.667	Poecilia_formosa
ENSG00000004059	ARF5	99	86.184	ENSPFOG00000017992	-	99	85.556	Poecilia_formosa
ENSG00000004059	ARF5	99	86.755	ENSPLAG00000015630	-	99	86.034	Poecilia_latipinna
ENSG00000004059	ARF5	100	91.667	ENSPLAG00000006742	arf5	100	91.667	Poecilia_latipinna
ENSG00000004059	ARF5	99	86.755	ENSPMEG00000004624	-	99	86.034	Poecilia_mexicana
ENSG00000004059	ARF5	100	91.667	ENSPMEG00000009605	arf5	100	91.667	Poecilia_mexicana
ENSG00000004059	ARF5	100	100.000	ENSPCOG00000027640	ARF5	100	100.000	Propithecus_coquereli
ENSG00000004059	ARF5	100	100.000	ENSPVAG00000013940	ARF5	100	100.000	Pteropus_vampyrus
ENSG00000004059	ARF5	100	91.667	ENSPNYG00000001663	arf5	100	91.667	Pundamilia_nyererei
ENSG00000004059	ARF5	100	87.500	ENSPNYG00000004931	-	99	87.151	Pundamilia_nyererei
ENSG00000004059	ARF5	100	72.778	ENSPNAG00000005054	-	100	72.778	Pygocentrus_nattereri
ENSG00000004059	ARF5	100	71.111	ENSPNAG00000004475	-	100	71.111	Pygocentrus_nattereri
ENSG00000004059	ARF5	100	92.778	ENSPNAG00000024427	-	100	92.778	Pygocentrus_nattereri
ENSG00000004059	ARF5	100	92.222	ENSPNAG00000004745	arf4a	100	92.222	Pygocentrus_nattereri
ENSG00000004059	ARF5	100	100.000	ENSRNOG00000007806	Arf5	100	100.000	Rattus_norvegicus
ENSG00000004059	ARF5	100	100.000	ENSRBIG00000039868	ARF5	100	100.000	Rhinopithecus_bieti
ENSG00000004059	ARF5	100	100.000	ENSRROG00000041157	ARF5	100	100.000	Rhinopithecus_roxellana
ENSG00000004059	ARF5	100	100.000	ENSSBOG00000021669	ARF5	100	100.000	Saimiri_boliviensis_boliviensis
ENSG00000004059	ARF5	100	98.889	ENSSHAG00000015053	ARF5	100	98.889	Sarcophilus_harrisii
ENSG00000004059	ARF5	100	90.556	ENSSFOG00015020707	ARF5	100	90.556	Scleropages_formosus
ENSG00000004059	ARF5	100	80.000	ENSSFOG00015007701	-	100	80.000	Scleropages_formosus
ENSG00000004059	ARF5	100	90.556	ENSSMAG00000011361	arf5	100	90.556	Scophthalmus_maximus
ENSG00000004059	ARF5	100	85.526	ENSSMAG00000004541	-	99	83.799	Scophthalmus_maximus
ENSG00000004059	ARF5	100	91.111	ENSSDUG00000005105	arf5	100	91.111	Seriola_dumerili
ENSG00000004059	ARF5	100	91.111	ENSSLDG00000017188	arf5	100	91.111	Seriola_lalandi_dorsalis
ENSG00000004059	ARF5	100	90.000	ENSSPAG00000014434	arf5	100	90.000	Stegastes_partitus
ENSG00000004059	ARF5	100	87.500	ENSSPAG00000022680	-	99	87.151	Stegastes_partitus
ENSG00000004059	ARF5	100	100.000	ENSSSCG00000016593	ARF5	100	100.000	Sus_scrofa
ENSG00000004059	ARF5	99	82.781	ENSTRUG00000025462	-	100	81.006	Takifugu_rubripes
ENSG00000004059	ARF5	99	83.444	ENSTNIG00000017954	-	100	81.006	Tetraodon_nigroviridis
ENSG00000004059	ARF5	99	90.066	ENSTNIG00000003348	arf5	100	89.385	Tetraodon_nigroviridis
ENSG00000004059	ARF5	90	99.383	ENSTTRG00000006043	ARF5	100	99.383	Tursiops_truncatus
ENSG00000004059	ARF5	100	100.000	ENSUAMG00000012982	ARF5	100	100.000	Ursus_americanus
ENSG00000004059	ARF5	100	100.000	ENSVVUG00000007062	ARF5	100	100.000	Vulpes_vulpes
ENSG00000004059	ARF5	99	86.755	ENSXCOG00000020384	-	99	86.034	Xiphophorus_couchianus
ENSG00000004059	ARF5	100	91.667	ENSXMAG00000015306	arf5	100	91.667	Xiphophorus_maculatus
ENSG00000004059	ARF5	99	86.755	ENSXMAG00000004558	-	99	86.034	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003924	GTPase activity	1993656.	TAS	Function
GO:0005515	protein binding	17030804.	IPI	Function
GO:0005525	GTP binding	21873635.	IBA	Function
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005794	Golgi apparatus	21873635.	IBA	Component
GO:0005886	plasma membrane	21873635.	IBA	Component
GO:0006886	intracellular protein transport	21873635.	IBA	Process
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	21873635.	IBA	Process
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	24768165.	IGI	Process
GO:0006893	Golgi to plasma membrane transport	21873635.	IBA	Process
GO:0016192	vesicle-mediated transport	21873635.	IBA	Process
GO:0048471	perinuclear region of cytoplasm	-	IEA	Component
GO:0070062	extracellular exosome	23533145.	HDA	Component