EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000005100 (Gene tree)
Gene ID: 56919
Gene Symbol: DHX33
Alias: FLJ21972|DKFZp762F2011|DDX33
Full Name: DEAH-box helicase 33
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 28,149 bases
Position: chr17:5,440,912-5,469,060
Accession: 16718
RBP type: canonical RBP
Summary: This gene encodes a member of the DEAD box protein family. The DEAD box proteins are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000225296	DEAD	PF00270.29	5.7e-06	1	1
ENSP00000413779	HA2	PF04408.23	1.6e-19	1	1
ENSP00000458925	HA2	PF04408.23	2.3e-19	1	1
ENSP00000225296	HA2	PF04408.23	2.7e-19	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
21930779	Identification of DHX33 as a mediator of rRNA synthesis and cell growth.	Mol Cell Biol	2011 Dec	Zhang Y	doi: 10.1128/MCB.05832-11
29870660	Recombinant DHX33 Protein Possesses Dual DNA/RNA Helicase Activity.	Biochemistry	2019 Jan 29	Wang X	doi: 10.1021/acs.biochem.8b00166
30684270	A 54-kDa short variant of DHX33 functions in regulating mRNA translation.	J Cell Physiol	2019 Jan 26	Su D	doi: 10.1002/jcp.28178

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000433302	DHX33-202	2225	XM_017024877	ENSP00000413779	483 (aa)	XP_016880366	Q05BE5
ENST00000574023	DHX33-204	2040	-	ENSP00000458203	93 (aa)	-	I3L0M5
ENST00000225296	DHX33-201	5618	-	ENSP00000225296	707 (aa)	-	Q9H6R0
ENST00000575153	DHX33-205	2416	-	-	- (aa)	-	-
ENST00000572490	DHX33-203	2564	-	ENSP00000458925	617 (aa)	-	I3L1L6

Gene Model

Click here to download ENSG00000005100's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa04621	NOD-like receptor signaling pathway	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000005100	Erythrocyte Indices	4.2420000E-006	-
ENSG00000005100	lycopene	3.5250000E-005	-

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000005100's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000005100	DHX33	90	42.085	ENSG00000150990	DHX37	73	41.007
ENSG00000005100	DHX33	91	44.665	ENSG00000101452	DHX35	92	44.665
ENSG00000005100	DHX33	91	42.478	ENSG00000140829	DHX38	78	41.905
ENSG00000005100	DHX33	82	36.816	ENSG00000174953	DHX36	92	34.951
ENSG00000005100	DHX33	89	47.393	ENSG00000067596	DHX8	89	30.894
ENSG00000005100	DHX33	91	30.344	ENSG00000144045	DQX1	91	30.643
ENSG00000005100	DHX33	91	46.177	ENSG00000204560	DHX16	90	44.639
ENSG00000005100	DHX33	98	33.281	ENSG00000108406	DHX40	88	44.915
ENSG00000005100	DHX33	89	42.724	ENSG00000109606	DHX15	80	42.724

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000005100	DHX33	100	68.883	ENSAPOG00000010132	dhx33	100	68.883	Acanthochromis_polyacanthus
ENSG00000005100	DHX33	92	87.018	ENSAMEG00000006026	DHX33	95	87.988	Ailuropoda_melanoleuca
ENSG00000005100	DHX33	100	69.307	ENSACIG00000012591	dhx33	100	69.307	Amphilophus_citrinellus
ENSG00000005100	DHX33	100	68.458	ENSAOCG00000007008	dhx33	100	68.458	Amphiprion_ocellaris
ENSG00000005100	DHX33	100	65.493	ENSAPEG00000013599	dhx33	100	65.493	Amphiprion_percula
ENSG00000005100	DHX33	100	68.883	ENSATEG00000005019	dhx33	100	68.883	Anabas_testudineus
ENSG00000005100	DHX33	92	84.683	ENSAPLG00000015593	DHX33	100	86.579	Anas_platyrhynchos
ENSG00000005100	DHX33	91	77.379	ENSACAG00000015095	DHX33	97	76.263	Anolis_carolinensis
ENSG00000005100	DHX33	100	95.652	ENSANAG00000037748	DHX33	100	97.626	Aotus_nancymaae
ENSG00000005100	DHX33	100	68.883	ENSACLG00000025610	dhx33	100	68.883	Astatotilapia_calliptera
ENSG00000005100	DHX33	100	71.429	ENSAMXG00000015875	dhx33	88	71.429	Astyanax_mexicanus
ENSG00000005100	DHX33	100	91.655	ENSBTAG00000032083	DHX33	100	91.372	Bos_taurus
ENSG00000005100	DHX33	88	38.218	WBGene00020263	let-355	77	38.218	Caenorhabditis_elegans
ENSG00000005100	DHX33	100	97.171	ENSCJAG00000011321	DHX33	100	97.171	Callithrix_jacchus
ENSG00000005100	DHX33	92	89.437	ENSCAFG00000015535	DHX33	99	90.865	Canis_familiaris
ENSG00000005100	DHX33	100	88.826	ENSCAFG00020016360	DHX33	100	88.543	Canis_lupus_dingo
ENSG00000005100	DHX33	100	91.655	ENSCHIG00000014722	DHX33	100	91.372	Capra_hircus
ENSG00000005100	DHX33	100	91.089	ENSTSYG00000005995	DHX33	100	91.089	Carlito_syrichta
ENSG00000005100	DHX33	92	93.486	ENSCAPG00000009660	DHX33	97	94.754	Cavia_aperea
ENSG00000005100	DHX33	98	92.785	ENSCPOG00000003681	DHX33	99	92.641	Cavia_porcellus
ENSG00000005100	DHX33	100	97.595	ENSCCAG00000027955	DHX33	100	97.595	Cebus_capucinus
ENSG00000005100	DHX33	100	97.878	ENSCATG00000029157	DHX33	100	97.878	Cercocebus_atys
ENSG00000005100	DHX33	100	93.026	ENSCLAG00000014171	DHX33	100	93.305	Chinchilla_lanigera
ENSG00000005100	DHX33	94	98.851	ENSCSAG00000012784	DHX33	93	82.378	Chlorocebus_sabaeus
ENSG00000005100	DHX33	94	86.364	ENSCHOG00000008707	DHX33	90	86.667	Choloepus_hoffmanni
ENSG00000005100	DHX33	100	80.339	ENSCPBG00000027741	DHX33	100	80.395	Chrysemys_picta_bellii
ENSG00000005100	DHX33	92	55.810	ENSCING00000009139	-	100	55.730	Ciona_intestinalis
ENSG00000005100	DHX33	100	98.303	ENSCANG00000034385	DHX33	100	98.303	Colobus_angolensis_palliatus
ENSG00000005100	DHX33	100	92.948	ENSCGRG00001023101	Dhx33	100	92.948	Cricetulus_griseus_chok1gshd
ENSG00000005100	DHX33	92	92.958	ENSCGRG00000010329	Dhx33	100	94.754	Cricetulus_griseus_crigri
ENSG00000005100	DHX33	100	69.590	ENSCSEG00000011017	dhx33	100	69.590	Cynoglossus_semilaevis
ENSG00000005100	DHX33	100	67.610	ENSCVAG00000008998	dhx33	100	67.327	Cyprinodon_variegatus
ENSG00000005100	DHX33	100	71.004	ENSDARG00000051785	dhx33	100	70.721	Danio_rerio
ENSG00000005100	DHX33	100	93.777	ENSDNOG00000016865	DHX33	92	93.494	Dasypus_novemcinctus
ENSG00000005100	DHX33	94	78.409	ENSDORG00000014344	Dhx33	100	89.510	Dipodomys_ordii
ENSG00000005100	DHX33	91	45.636	FBgn0032194	CG4901	94	45.636	Drosophila_melanogaster
ENSG00000005100	DHX33	90	43.069	ENSEBUG00000008342	dhx33	95	44.593	Eptatretus_burgeri
ENSG00000005100	DHX33	100	95.474	ENSEASG00005015338	DHX33	100	95.332	Equus_asinus_asinus
ENSG00000005100	DHX33	100	95.332	ENSECAG00000010272	DHX33	100	95.191	Equus_caballus
ENSG00000005100	DHX33	87	88.923	ENSEEUG00000008589	-	72	96.491	Erinaceus_europaeus
ENSG00000005100	DHX33	100	69.165	ENSELUG00000020257	dhx33	100	69.165	Esox_lucius
ENSG00000005100	DHX33	100	88.967	ENSFCAG00000014755	DHX33	100	88.967	Felis_catus
ENSG00000005100	DHX33	92	77.289	ENSFALG00000009785	DHX33	99	75.149	Ficedula_albicollis
ENSG00000005100	DHX33	100	88.826	ENSFDAG00000003334	DHX33	100	88.826	Fukomys_damarensis
ENSG00000005100	DHX33	86	67.585	ENSFHEG00000014253	dhx33	95	67.261	Fundulus_heteroclitus
ENSG00000005100	DHX33	100	68.317	ENSGMOG00000012350	dhx33	100	68.317	Gadus_morhua
ENSG00000005100	DHX33	100	68.034	ENSGAFG00000014811	dhx33	96	73.977	Gambusia_affinis
ENSG00000005100	DHX33	100	68.883	ENSGACG00000020229	dhx33	100	69.448	Gasterosteus_aculeatus
ENSG00000005100	DHX33	92	85.366	ENSGAGG00000013448	DHX33	99	85.366	Gopherus_agassizii
ENSG00000005100	DHX33	100	99.151	ENSGGOG00000002748	DHX33	100	99.151	Gorilla_gorilla
ENSG00000005100	DHX33	100	68.883	ENSHBUG00000017415	dhx33	100	68.883	Haplochromis_burtoni
ENSG00000005100	DHX33	100	92.500	ENSHGLG00000014753	DHX33	100	92.350	Heterocephalus_glaber_female
ENSG00000005100	DHX33	94	94.570	ENSHGLG00100012963	DHX33	99	94.368	Heterocephalus_glaber_male
ENSG00000005100	DHX33	100	68.317	ENSHCOG00000011161	dhx33	100	68.317	Hippocampus_comes
ENSG00000005100	DHX33	100	71.711	ENSIPUG00000011594	dhx33	100	71.711	Ictalurus_punctatus
ENSG00000005100	DHX33	100	93.927	ENSSTOG00000003298	DHX33	100	94.492	Ictidomys_tridecemlineatus
ENSG00000005100	DHX33	100	91.796	ENSJJAG00000016626	Dhx33	100	91.513	Jaculus_jaculus
ENSG00000005100	DHX33	100	68.741	ENSKMAG00000013595	dhx33	100	68.600	Kryptolebias_marmoratus
ENSG00000005100	DHX33	100	69.590	ENSLBEG00000005703	dhx33	100	69.590	Labrus_bergylta
ENSG00000005100	DHX33	99	75.036	ENSLACG00000018174	DHX33	94	80.062	Latimeria_chalumnae
ENSG00000005100	DHX33	90	63.701	ENSLOCG00000002764	dhx33	97	63.701	Lepisosteus_oculatus
ENSG00000005100	DHX33	100	93.512	ENSLAFG00000007136	DHX33	100	93.230	Loxodonta_africana
ENSG00000005100	DHX33	100	98.161	ENSMFAG00000042578	DHX33	100	98.161	Macaca_fascicularis
ENSG00000005100	DHX33	100	98.161	ENSMMUG00000006594	DHX33	100	98.161	Macaca_mulatta
ENSG00000005100	DHX33	94	98.851	ENSMNEG00000034809	DHX33	100	91.304	Macaca_nemestrina
ENSG00000005100	DHX33	100	98.020	ENSMLEG00000034236	DHX33	100	98.020	Mandrillus_leucophaeus
ENSG00000005100	DHX33	100	69.873	ENSMAMG00000005936	dhx33	100	70.438	Mastacembelus_armatus
ENSG00000005100	DHX33	100	68.741	ENSMZEG00005023292	dhx33	100	68.741	Maylandia_zebra
ENSG00000005100	DHX33	92	83.888	ENSMGAG00000003125	DHX33	100	85.993	Meleagris_gallopavo
ENSG00000005100	DHX33	100	93.211	ENSMAUG00000011100	Dhx33	100	93.069	Mesocricetus_auratus
ENSG00000005100	DHX33	100	95.898	ENSMICG00000012715	DHX33	100	95.898	Microcebus_murinus
ENSG00000005100	DHX33	100	92.928	ENSMOCG00000016069	Dhx33	100	92.645	Microtus_ochrogaster
ENSG00000005100	DHX33	100	66.761	ENSMMOG00000005732	dhx33	100	66.761	Mola_mola
ENSG00000005100	DHX33	99	78.895	ENSMODG00000016649	DHX33	99	78.470	Monodelphis_domestica
ENSG00000005100	DHX33	99	69.405	ENSMALG00000000923	dhx33	99	69.405	Monopterus_albus
ENSG00000005100	DHX33	100	92.928	MGP_CAROLIEiJ_G0016657	Dhx33	100	92.928	Mus_caroli
ENSG00000005100	DHX33	100	92.645	ENSMUSG00000040620	Dhx33	100	92.362	Mus_musculus
ENSG00000005100	DHX33	100	92.938	MGP_PahariEiJ_G0017788	Dhx33	100	92.797	Mus_pahari
ENSG00000005100	DHX33	100	92.645	MGP_SPRETEiJ_G0017493	Dhx33	100	92.504	Mus_spretus
ENSG00000005100	DHX33	87	89.326	ENSMPUG00000011250	DHX33	100	89.326	Mustela_putorius_furo
ENSG00000005100	DHX33	100	91.983	ENSMLUG00000014439	DHX33	92	92.264	Myotis_lucifugus
ENSG00000005100	DHX33	100	92.504	ENSNGAG00000017139	Dhx33	100	92.504	Nannospalax_galili
ENSG00000005100	DHX33	100	68.600	ENSNBRG00000017674	dhx33	100	69.165	Neolamprologus_brichardi
ENSG00000005100	DHX33	67	97.846	ENSNLEG00000009098	-	100	98.267	Nomascus_leucogenys
ENSG00000005100	DHX33	83	79.966	ENSMEUG00000009202	DHX33	100	79.966	Notamacropus_eugenii
ENSG00000005100	DHX33	100	88.967	ENSOPRG00000013163	DHX33	100	89.958	Ochotona_princeps
ENSG00000005100	DHX33	100	92.645	ENSODEG00000017026	DHX33	100	92.504	Octodon_degus
ENSG00000005100	DHX33	99	69.373	ENSONIG00000017480	dhx33	95	69.373	Oreochromis_niloticus
ENSG00000005100	DHX33	58	66.140	ENSOANG00000000524	-	100	66.140	Ornithorhynchus_anatinus
ENSG00000005100	DHX33	63	70.380	ENSOANG00000002808	-	100	70.380	Ornithorhynchus_anatinus
ENSG00000005100	DHX33	100	86.890	ENSOCUG00000004805	DHX33	100	86.750	Oryctolagus_cuniculus
ENSG00000005100	DHX33	100	67.327	ENSORLG00000011817	dhx33	100	67.044	Oryzias_latipes
ENSG00000005100	DHX33	100	67.751	ENSORLG00020016766	dhx33	100	67.468	Oryzias_latipes_hni
ENSG00000005100	DHX33	91	72.231	ENSORLG00015022753	dhx33	98	72.231	Oryzias_latipes_hsok
ENSG00000005100	DHX33	99	68.272	ENSOMEG00000010438	dhx33	99	68.130	Oryzias_melastigma
ENSG00000005100	DHX33	99	94.625	ENSOGAG00000001611	DHX33	93	94.499	Otolemur_garnettii
ENSG00000005100	DHX33	93	93.020	ENSOARG00000003235	DHX33	96	93.020	Ovis_aries
ENSG00000005100	DHX33	100	99.576	ENSPPAG00000038926	DHX33	100	99.576	Pan_paniscus
ENSG00000005100	DHX33	100	87.836	ENSPPRG00000009202	DHX33	100	87.694	Panthera_pardus
ENSG00000005100	DHX33	68	71.608	ENSPTIG00000018141	DHX33	85	71.784	Panthera_tigris_altaica
ENSG00000005100	DHX33	100	99.434	ENSPTRG00000008632	DHX33	100	99.434	Pan_troglodytes
ENSG00000005100	DHX33	100	97.878	ENSPANG00000024297	DHX33	100	97.878	Papio_anubis
ENSG00000005100	DHX33	100	72.560	ENSPKIG00000017401	dhx33	100	72.560	Paramormyrops_kingsleyae
ENSG00000005100	DHX33	92	83.099	ENSPSIG00000006293	DHX33	93	84.943	Pelodiscus_sinensis
ENSG00000005100	DHX33	100	68.883	ENSPMGG00000013896	dhx33	100	68.883	Periophthalmus_magnuspinnatus
ENSG00000005100	DHX33	100	92.928	ENSPEMG00000016472	Dhx33	100	92.786	Peromyscus_maniculatus_bairdii
ENSG00000005100	DHX33	100	79.379	ENSPCIG00000020074	DHX33	100	79.096	Phascolarctos_cinereus
ENSG00000005100	DHX33	100	67.327	ENSPFOG00000009426	dhx33	100	67.044	Poecilia_formosa
ENSG00000005100	DHX33	100	67.610	ENSPLAG00000017730	dhx33	100	67.327	Poecilia_latipinna
ENSG00000005100	DHX33	100	67.610	ENSPMEG00000012075	dhx33	99	73.021	Poecilia_mexicana
ENSG00000005100	DHX33	100	67.373	ENSPREG00000008239	dhx33	100	67.090	Poecilia_reticulata
ENSG00000005100	DHX33	100	99.010	ENSPPYG00000007871	DHX33	92	99.010	Pongo_abelii
ENSG00000005100	DHX33	100	83.192	ENSPCAG00000006190	DHX33	100	82.910	Procavia_capensis
ENSG00000005100	DHX33	100	96.040	ENSPCOG00000007524	DHX33	100	96.040	Propithecus_coquereli
ENSG00000005100	DHX33	100	93.918	ENSPVAG00000002467	DHX33	100	93.777	Pteropus_vampyrus
ENSG00000005100	DHX33	100	68.741	ENSPNYG00000021648	dhx33	100	69.307	Pundamilia_nyererei
ENSG00000005100	DHX33	100	71.570	ENSPNAG00000020048	dhx33	100	71.570	Pygocentrus_nattereri
ENSG00000005100	DHX33	100	93.352	ENSRNOG00000007054	Dhx33	100	93.211	Rattus_norvegicus
ENSG00000005100	DHX33	100	97.878	ENSRBIG00000040087	DHX33	100	97.878	Rhinopithecus_bieti
ENSG00000005100	DHX33	100	98.020	ENSRROG00000038052	DHX33	100	98.020	Rhinopithecus_roxellana
ENSG00000005100	DHX33	88	40.000	YKL078W	-	87	39.969	Saccharomyces_cerevisiae
ENSG00000005100	DHX33	100	94.908	ENSSBOG00000020529	DHX33	100	94.908	Saimiri_boliviensis_boliviensis
ENSG00000005100	DHX33	100	76.560	ENSSHAG00000002762	DHX33	100	83.524	Sarcophilus_harrisii
ENSG00000005100	DHX33	99	74.716	ENSSFOG00015001783	dhx33	99	74.432	Scleropages_formosus
ENSG00000005100	DHX33	100	69.165	ENSSMAG00000000497	dhx33	100	69.731	Scophthalmus_maximus
ENSG00000005100	DHX33	100	68.317	ENSSDUG00000017798	dhx33	100	68.317	Seriola_dumerili
ENSG00000005100	DHX33	100	67.751	ENSSLDG00000020132	dhx33	100	67.751	Seriola_lalandi_dorsalis
ENSG00000005100	DHX33	100	89.533	ENSSARG00000009813	DHX33	100	89.250	Sorex_araneus
ENSG00000005100	DHX33	67	83.385	ENSSPUG00000010498	-	100	84.406	Sphenodon_punctatus
ENSG00000005100	DHX33	67	70.218	ENSSPAG00000003711	-	100	70.218	Stegastes_partitus
ENSG00000005100	DHX33	100	68.458	ENSSPAG00000012860	dhx33	100	68.458	Stegastes_partitus
ENSG00000005100	DHX33	100	87.270	ENSSSCG00000039064	DHX33	100	86.846	Sus_scrofa
ENSG00000005100	DHX33	92	76.761	ENSTGUG00000004226	DHX33	100	77.778	Taeniopygia_guttata
ENSG00000005100	DHX33	100	68.883	ENSTRUG00000003395	dhx33	100	68.741	Takifugu_rubripes
ENSG00000005100	DHX33	99	64.306	ENSTNIG00000008546	dhx33	100	64.306	Tetraodon_nigroviridis
ENSG00000005100	DHX33	92	84.091	ENSTBEG00000008531	DHX33	59	96.894	Tupaia_belangeri
ENSG00000005100	DHX33	76	85.193	ENSTTRG00000014788	DHX33	84	87.598	Tursiops_truncatus
ENSG00000005100	DHX33	100	90.240	ENSUAMG00000012182	DHX33	100	89.958	Ursus_americanus
ENSG00000005100	DHX33	95	90.000	ENSVVUG00000027336	DHX33	99	90.715	Vulpes_vulpes
ENSG00000005100	DHX33	99	76.681	ENSXETG00000009173	dhx33	96	76.571	Xenopus_tropicalis
ENSG00000005100	DHX33	100	67.751	ENSXCOG00000004969	dhx33	100	67.468	Xiphophorus_couchianus
ENSG00000005100	DHX33	100	67.893	ENSXMAG00000005679	dhx33	100	67.893	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000182	rDNA binding	21930779.	IDA	Function
GO:0003723	RNA binding	22658674.	HDA	Function
GO:0003723	RNA binding	21873635.	IBA	Function
GO:0003725	double-stranded RNA binding	23871209.	IDA	Function
GO:0003729	mRNA binding	26100019.	IDA	Function
GO:0005515	protein binding	23871209.26100019.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005634	nucleus	23871209.	IDA	Component
GO:0005654	nucleoplasm	21930779.	IDA	Component
GO:0005730	nucleolus	21873635.	IBA	Component
GO:0005730	nucleolus	21930779.	IDA	Component
GO:0005737	cytoplasm	23871209.	IDA	Component
GO:0006413	translational initiation	-	IEA	Process
GO:0032481	positive regulation of type I interferon production	-	ISS	Process
GO:0033613	activating transcription factor binding	-	IEA	Function
GO:0034459	ATP-dependent 3'-5' RNA helicase activity	21873635.	IBA	Function
GO:0043023	ribosomal large subunit binding	26100019.	IPI	Function
GO:0043410	positive regulation of MAPK cascade	-	ISS	Process
GO:0045943	positive regulation of transcription by RNA polymerase I	21873635.	IBA	Process
GO:0045943	positive regulation of transcription by RNA polymerase I	21930779.	IDA	Process
GO:0051092	positive regulation of NF-kappaB transcription factor activity	-	ISS	Process
GO:0072559	NLRP3 inflammasome complex	23871209.	IDA	Component
GO:1900227	positive regulation of NLRP3 inflammasome complex assembly	23871209.	IDA	Process